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Search of human proteins with 115334682
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115334682 SNAP25-interacting protein [Homo sapiens]
(1183 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115334682 SNAP25-interacting protein [Homo sapiens] 2338 0.0
gi|50843820 sickle tail isoform 1 [Homo sapiens] 649 0.0
gi|148612813 sickle tail isoform 2 [Homo sapiens] 644 0.0
gi|148612857 sickle tail isoform 3 [Homo sapiens] 617 e-176
gi|110832843 TBP-associated factor 4 [Homo sapiens] 64 9e-10
gi|110611914 progesterone receptor [Homo sapiens] 60 9e-09
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 56 2e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 54 7e-07
gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo sa... 54 7e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 54 9e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 53 2e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 53 2e-06
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 53 2e-06
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 52 3e-06
gi|150378478 PR domain containing 8 [Homo sapiens] 52 3e-06
gi|150378439 PR domain containing 8 [Homo sapiens] 52 3e-06
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 52 3e-06
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 51 6e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 51 7e-06
gi|153792074 proline rich 12 [Homo sapiens] 51 7e-06
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 50 1e-05
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 49 2e-05
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 49 3e-05
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 49 4e-05
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 49 4e-05
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 49 4e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 49 4e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 49 4e-05
gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapi... 49 4e-05
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 48 5e-05
>gi|115334682 SNAP25-interacting protein [Homo sapiens]
Length = 1183
Score = 2338 bits (6060), Expect = 0.0
Identities = 1183/1183 (100%), Positives = 1183/1183 (100%)
Query: 1 MGNAPSQDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVI 60
MGNAPSQDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVI
Sbjct: 1 MGNAPSQDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVI 60
Query: 61 AAQSLEALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQPNYWSFKTRSSR 120
AAQSLEALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQPNYWSFKTRSSR
Sbjct: 61 AAQSLEALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQPNYWSFKTRSSR 120
Query: 121 HTQGAQPGLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSP 180
HTQGAQPGLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSP
Sbjct: 121 HTQGAQPGLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSP 180
Query: 181 GVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVF 240
GVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVF
Sbjct: 181 GVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVF 240
Query: 241 YELEDVRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPA 300
YELEDVRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPA
Sbjct: 241 YELEDVRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPA 300
Query: 301 PHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQG 360
PHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQG
Sbjct: 301 PHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQG 360
Query: 361 VSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAY 420
VSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAY
Sbjct: 361 VSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAY 420
Query: 421 PGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLAD 480
PGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLAD
Sbjct: 421 PGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLAD 480
Query: 481 VAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPP 540
VAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPP
Sbjct: 481 VAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPP 540
Query: 541 SELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEK 600
SELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEK
Sbjct: 541 SELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEK 600
Query: 601 IEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQMQLHLRGLQNS 660
IEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQMQLHLRGLQNS
Sbjct: 601 IEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQMQLHLRGLQNS 660
Query: 661 ASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQRTLVEEERL 720
ASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQRTLVEEERL
Sbjct: 661 ASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQRTLVEEERL 720
Query: 721 RYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGETLTELKAHF 780
RYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGETLTELKAHF
Sbjct: 721 RYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGETLTELKAHF 780
Query: 781 PGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRGVTDTLAQIRRQVDEGVWPPPNNL 840
PGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRGVTDTLAQIRRQVDEGVWPPPNNL
Sbjct: 781 PGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRGVTDTLAQIRRQVDEGVWPPPNNL 840
Query: 841 LSQSPKKVTAETDFNKSVDFEMPPPSPPLNLHELSGPAEGASLTPKGGNPTKGLDTPGKR 900
LSQSPKKVTAETDFNKSVDFEMPPPSPPLNLHELSGPAEGASLTPKGGNPTKGLDTPGKR
Sbjct: 841 LSQSPKKVTAETDFNKSVDFEMPPPSPPLNLHELSGPAEGASLTPKGGNPTKGLDTPGKR 900
Query: 901 SVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAHPGPAP 960
SVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAHPGPAP
Sbjct: 901 SVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAHPGPAP 960
Query: 961 TPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLT 1020
TPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLT
Sbjct: 961 TPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLT 1020
Query: 1021 TTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKDED 1080
TTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKDED
Sbjct: 1021 TTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKDED 1080
Query: 1081 DEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQAQQQA 1140
DEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQAQQQA
Sbjct: 1081 DEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQAQQQA 1140
Query: 1141 TKPSKEMSGSNETSSPVSEKPSASRTSIPVLTSFGARNSSISF 1183
TKPSKEMSGSNETSSPVSEKPSASRTSIPVLTSFGARNSSISF
Sbjct: 1141 TKPSKEMSGSNETSSPVSEKPSASRTSIPVLTSFGARNSSISF 1183
>gi|50843820 sickle tail isoform 1 [Homo sapiens]
Length = 1943
Score = 649 bits (1674), Expect = 0.0
Identities = 453/1172 (38%), Positives = 642/1172 (54%), Gaps = 142/1172 (12%)
Query: 7 QDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVIAAQSLE 66
Q+ + + + S +DAE R L G GS + N+ RRHT+ +S +
Sbjct: 23 QEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNI------PRRHTLGGPRSSK 76
Query: 67 ALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQPNYWSFKTRSSRHTQGAQ 126
+ G+Q ++ DRKR+AF++HLK KYP HA A+ G Q+R+R+Q TRS + + Q
Sbjct: 77 EILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQ-------TRSPKLSHSPQ 129
Query: 127 P-GLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFL 185
P L D LS SA+SLE MSE + P FSR +R R SLP+ RS +QTK RS GVL+L
Sbjct: 130 PPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYL 189
Query: 186 QFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELED 245
Q+G+ET+++ + +E++S DT+ AL FPQ+LTM ML+SP+ AI IKDE+RNV+YEL D
Sbjct: 190 QYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELND 249
Query: 246 VRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLR--REMVYASRESSPTRRLNNLSPAPHL 303
VR+IQDRS++K+Y K+P +A NGD+R RE+VYA + R + + PH
Sbjct: 250 VRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHA 309
Query: 304 ASGSPPPG-LPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVS 362
SPP +P +P PS SR+ Y G R G+ +R+ P ++ +S
Sbjct: 310 IPNSPPSTPVPHSMP-------PSPSRIPYGGTRSMVVPGNATI-PRDRISSLPVSRPIS 361
Query: 363 PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAA-AGDPFAYP 421
PSPSAILERRDVKPDED++ K + + + EG YADPY L HEGR+S+A++ G P P
Sbjct: 362 PSPSAILERRDVKPDEDMSGK--NIAMYRNEGFYADPY-LYHEGRMSIASSHGGHPLDVP 418
Query: 422 GAGGLYKRGSVRSLSTYSAAALQSDL--EDSLYKAAGGGGP-LYGDGYGFRLPPSSPQKL 478
Y R ++RS S Y ++Q+++ E SLY+ P + G + PP+SP ++
Sbjct: 419 DHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRV 478
Query: 479 ADVA-----APPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSA 533
+D+ A PPH+ P R SP RQ+F+K+ G+ V+ E P RSA
Sbjct: 479 SDLRMIDMHAHYNAHGPPHTMQ---PDRASPSRQAFKKEPGTL-VYIEKP----RSAAGL 530
Query: 534 STAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSE 593
S+ +L P E+ + + KD ETRERM+AMEKQIASLTGLVQSAL +G
Sbjct: 531 SSL----VDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKG-- 584
Query: 594 PETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSA--SSTPAGQPTAVSRLQMQ 651
P T K + S+ + + S+G VSG SA S+ P QP V +
Sbjct: 585 PITSYSK-DASSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIH 643
Query: 652 LHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQ 711
+ L ++ S ++LR QLQQ+R+LQLQNQE +RA++K+ E E+S +V E +R EDP+QRQ
Sbjct: 644 MSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQ 703
Query: 712 RTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGE 771
R LVE+ER +YL++EE I ++L +LE VE +++D + RLV ++E+ A +L+Q+GE
Sbjct: 704 RVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGE 763
Query: 772 TLTELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRG-----------VTD 820
+ LK FP LQ+KMR +LR+EVEAV+FLKEEP +LD LLKR R VTD
Sbjct: 764 AVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTD 823
Query: 821 TL------AQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFNKS-----VDFEMPPPS--- 866
L AQ + + L SQ T+ F+ + E+ P S
Sbjct: 824 GLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMM 883
Query: 867 ----------------------PPLNL-HELSGPAEGASLT--------------PKGGN 889
P NL H S PA T P G+
Sbjct: 884 VRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGS 943
Query: 890 PTKGLDTPGKRSV---DKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIP 946
+ L SV ++AVS+E AE+ WEEKR L Y+ K+ +LLEE QA ++K+IP
Sbjct: 944 AMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIP 1003
Query: 947 DLDCASKAHPGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPP 1006
+L+ GP P D AP + P+ + ++L S PPP
Sbjct: 1004 NLEMPPAT--GPLPRGD-----APVDKVELSEDSPNSEQDLEKL-------GGKSPPPPP 1049
Query: 1007 PPPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPA 1066
PPPRRS+ GLTTTR+G+VV T +K++ KA SE+ PQ + + +E A
Sbjct: 1050 PPPRRSYLPGSGLTTTRSGDVVYTGRKEN-ITAKASSEDAG-PSPQTRATKYPAEEPASA 1107
Query: 1067 ---STPPIMASAIKDEDDE----DRIIAELES 1091
S PP+ S+ KDE++E D+I+AEL++
Sbjct: 1108 WTPSPPPVTTSSSKDEEEEEEEGDKIMAELQA 1139
Score = 34.3 bits (77), Expect = 0.72
Identities = 105/466 (22%), Positives = 166/466 (35%), Gaps = 66/466 (14%)
Query: 100 GQQDRMREQPNYWSFKTRSSRHTQGAQPGLADQAAKLSYASAESLETMSEAELPLGF-SR 158
GQQ + QP+ + +TR+ G Q + K S+ + + E E F S
Sbjct: 1514 GQQVETKSQPHSLATETRNP----GGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESP 1569
Query: 159 MNRFRQSLPLSRSASQTKLRSPGVLFLQFGEETRRVHITHEVSSLDTLHAL-------IA 211
+F+ P + A+ T+ G + G++T +V + E TL IA
Sbjct: 1570 KKKFKFKFPKKQLAALTQAIRTGT---KTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIA 1626
Query: 212 HMFPQKL---TMGMLKSPN----TAILIKDEARNVFYELEDVRDIQDRSIIKIYRKEPLY 264
P+ T+ + P+ + I DE R Y D + + + +
Sbjct: 1627 RSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPK 1686
Query: 265 AAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGS 324
A S +N D + ++E+SP R L L P + PP +PS G SG+
Sbjct: 1687 ALVDTSCSSNRDSVASSSHIAQEASP-RPL--LVPDEGPTALEPPTSIPSASRKG-SSGA 1742
Query: 325 PSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKA 384
P SR+ PV +A+ G G S + + R + A K+
Sbjct: 1743 PQTSRM-------------PVPMSAKNRPGTLDKPG---KQSKLQDPRQYRQANGSAKKS 1786
Query: 385 GGMVLVKGEGLYADPYGLLHEGR---LSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAA 441
GG L A L SL +++GD P + LS +
Sbjct: 1787 GGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGP 1846
Query: 442 ALQSDLEDSLYKAAGGGGPLY------GDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPY 495
S SL + G + G G+ P S G PPP S
Sbjct: 1847 PAHSA---SLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQN---------GRAPPPLSFS 1894
Query: 496 SGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPS 541
S PPS S V + + G+ ++ +P + A + S++ A PS
Sbjct: 1895 SSPPSPASSVSLN-QGAKGTRTI--HTPSLTSYKAQNGSSSKATPS 1937
Score = 31.6 bits (70), Expect = 4.7
Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 21/150 (14%)
Query: 472 PSSPQKLADVAAPPGGPPPP-----HSPYSG-PPSRGSPVRQSFRKDSGSSSVFAESPGG 525
P+S Q L + PPPP + P SG +R V + RK++ ++ +E G
Sbjct: 1031 PNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGP 1090
Query: 526 KTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDT-ETRERMEAMEKQIASLTGLV 584
++ + A P S P P PPV + + E E +K +A L
Sbjct: 1091 SPQTRATKYPAEEPASAWTPSP---------PPVTTSSSKDEEEEEEEGDKIMAELQAFQ 1141
Query: 585 QSALL-----RGSEPETPSEKIEGSNGAAT 609
+ + + +EP ++ + AT
Sbjct: 1142 KCSFMDVNSNSHAEPSRADSHVKDTRSGAT 1171
>gi|148612813 sickle tail isoform 2 [Homo sapiens]
Length = 1264
Score = 644 bits (1661), Expect = 0.0
Identities = 457/1198 (38%), Positives = 654/1198 (54%), Gaps = 149/1198 (12%)
Query: 71 LQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQPNYWSFKTRSSRHTQGAQP-GL 129
+Q ++ DRKR+AF++HLK KYP HA A+ G Q+R+R+Q TRS + + QP L
Sbjct: 1 MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQ-------TRSPKLSHSPQPPSL 53
Query: 130 ADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFLQFGE 189
D LS SA+SLE MSE + P FSR +R R SLP+ RS +QTK RS GVL+LQ+G+
Sbjct: 54 GDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGD 113
Query: 190 ETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELEDVRDI 249
ET+++ + +E++S DT+ AL FPQ+LTM ML+SP+ AI IKDE+RNV+YEL DVR+I
Sbjct: 114 ETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNI 173
Query: 250 QDRSIIKIYRKEPLYAAFPGSHLTNGDLR--REMVYASRESSPTRRLNNLSPAPHLASGS 307
QDRS++K+Y K+P +A NGD+R RE+VYA + R + + PH S
Sbjct: 174 QDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNS 233
Query: 308 PPPG-LPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVSPSPS 366
PP +P +P PS SR+ Y G R G+ +R+ P ++ +SPSPS
Sbjct: 234 PPSTPVPHSMP-------PSPSRIPYGGTRSMVVPGNATI-PRDRISSLPVSRPISPSPS 285
Query: 367 AILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAA-AGDPFAYPGAGG 425
AILERRDVKPDED++ K + + + EG YADPY L HEGR+S+A++ G P P
Sbjct: 286 AILERRDVKPDEDMSGK--NIAMYRNEGFYADPY-LYHEGRMSIASSHGGHPLDVPDHII 342
Query: 426 LYKRGSVRSLSTYSAAALQSDL--EDSLYKAAGGGGP-LYGDGYGFRLPPSSPQKLADVA 482
Y R ++RS S Y ++Q+++ E SLY+ P + G + PP+SP +++D+
Sbjct: 343 AYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLR 402
Query: 483 -----APPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAG 537
A PPH+ P R SP RQ+F+K+ G+ V+ E P RSA S+
Sbjct: 403 MIDMHAHYNAHGPPHTMQ---PDRASPSRQAFKKEPGTL-VYIEKP----RSAAGLSSL- 453
Query: 538 APPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETP 597
+L P E+ + + KD ETRERM+AMEKQIASLTGLVQSAL +G P T
Sbjct: 454 ---VDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKG--PITS 508
Query: 598 SEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSA--SSTPAGQPTAVSRLQMQLHLR 655
K + S+ + + S+G VSG SA S+ P QP V + + L
Sbjct: 509 YSK-DASSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLL 567
Query: 656 GLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQRTLV 715
++ S ++LR QLQQ+R+LQLQNQE +RA++K+ E E+S +V E +R EDP+QRQR LV
Sbjct: 568 EMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLV 627
Query: 716 EEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGETLTE 775
E+ER +YL++EE I ++L +LE VE +++D + RLV ++E+ A +L+Q+GE +
Sbjct: 628 EQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVAT 687
Query: 776 LKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRG-----------VTDTL-- 822
LK FP LQ+KMR +LR+EVEAV+FLKEEP +LD LLKR R VTD L
Sbjct: 688 LKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLK 747
Query: 823 ----AQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFNKS-----VDFEMPPPS------- 866
AQ + + L SQ T+ F+ + E+ P S
Sbjct: 748 GTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHA 807
Query: 867 ------------------PPLNL-HELSGPAEGASLT--------------PKGGNPTKG 893
P NL H S PA T P G+ +
Sbjct: 808 QSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQS 867
Query: 894 LDTPGKRSV---DKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDC 950
L SV ++AVS+E AE+ WEEKR L Y+ K+ +LLEE QA ++K+IP+L+
Sbjct: 868 LFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEM 927
Query: 951 ASKAHPGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPR 1010
GP P D AP + P+ + ++L S PPPPPPR
Sbjct: 928 PPAT--GPLPRGD-----APVDKVELSEDSPNSEQDLEKL-------GGKSPPPPPPPPR 973
Query: 1011 RSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPA---S 1067
RS+ GLTTTR+G+VV T +K++ KA SE+ PQ + + +E A S
Sbjct: 974 RSYLPGSGLTTTRSGDVVYTGRKEN-ITAKASSEDAG-PSPQTRATKYPAEEPASAWTPS 1031
Query: 1068 TPPIMASAIKDEDDE----DRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSK 1123
PP+ S+ KDE++E D+I+AEL+ G+ ++ P +A+ + G+ DK
Sbjct: 1032 PPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVP-----MSAKNRPGTLDKP- 1085
Query: 1124 HGKQRAEYMRIQAQQQATKPSKEMSGSNETSSPVSEKPSASRTSIPVLTSFGARNSSI 1181
GKQ ++ + +QA +K+ G + +S PS + IP L+ ++SS+
Sbjct: 1086 -GKQ-SKLQDPRQYRQANGSAKKSGGDFKPTS-----PSLPASKIPALSPSSGKSSSL 1136
>gi|148612857 sickle tail isoform 3 [Homo sapiens]
Length = 1309
Score = 617 bits (1591), Expect = e-176
Identities = 453/1263 (35%), Positives = 658/1263 (52%), Gaps = 192/1263 (15%)
Query: 7 QDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVIAAQSLE 66
Q+ + + + S +DAE R L G GS + N+ RRHT+ +S +
Sbjct: 23 QEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNI------PRRHTLGGPRSSK 76
Query: 67 ALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQPNYWSFKTRSSRHTQGAQ 126
+ G+Q ++ DRKR+AF++HLK KYP HA A+ G Q+R+R+Q TRS + + Q
Sbjct: 77 EILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQ-------TRSPKLSHSPQ 129
Query: 127 P-GLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFL 185
P L D LS SA+SLE MSE + P FSR +R R SLP+ RS +QTK RS GVL+L
Sbjct: 130 PPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYL 189
Query: 186 QFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELED 245
Q+G+ET+++ + +E++S DT+ AL FPQ+LTM ML+SP+ AI IKDE+RNV+YEL D
Sbjct: 190 QYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELND 249
Query: 246 VRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLR--REMVYASRESSPTRRLNNLSPAPHL 303
VR+IQDRS++K+Y K+P +A NGD+R RE+VYA + R + + PH
Sbjct: 250 VRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHA 309
Query: 304 ASGSPPPG-LPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVS 362
SPP +P +P PS SR+ Y G R G+ +R+ P ++ +S
Sbjct: 310 IPNSPPSTPVPHSMP-------PSPSRIPYGGTRSMVVPGNATI-PRDRISSLPVSRPIS 361
Query: 363 PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAA-AGDPFAYP 421
PSPSAILERRDVKPDED++ K + + + EG YADPY L HEGR+S+A++ G P P
Sbjct: 362 PSPSAILERRDVKPDEDMSGK--NIAMYRNEGFYADPY-LYHEGRMSIASSHGGHPLDVP 418
Query: 422 GAGGLYKRGSVRSLSTYSAAALQSDL--EDSLYKAAGGGGP-LYGDGYGFRLPPSSPQKL 478
Y R ++RS S Y ++Q+++ E SLY+ P + G + PP+SP ++
Sbjct: 419 DHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRV 478
Query: 479 ADVA-----APPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSA 533
+D+ A PPH+ P R SP RQ+F+K+ G+ V+ E P RSA
Sbjct: 479 SDLRMIDMHAHYNAHGPPHTMQ---PDRASPSRQAFKKEPGTL-VYIEKP----RSAAGL 530
Query: 534 STAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSE 593
S SLV GPP+ MEKQ+ S +
Sbjct: 531 S----------------SLVDLGPPL-------------MEKQV-----FAYSTATIPKD 556
Query: 594 PETPSEKIEGS---NGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQM 650
ET + ++ + N + P SGG+ A S+ P QP V +
Sbjct: 557 RETSEKMMKTTANRNHTDSAGTPHVSGGKMLSALE---------STVPPSQPPPVGTSAI 607
Query: 651 QLHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQR 710
+ L ++ S ++LR QLQQ+R+LQLQNQE +RA++K+ E E+S +V E +R EDP+QR
Sbjct: 608 HMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQR 667
Query: 711 QRTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLG 770
QR LVE+ER +YL++EE I ++L +LE VE +++D + RLV ++E+ A +L+Q+G
Sbjct: 668 QRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVG 727
Query: 771 ETLTELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRG-----------VT 819
E + LK FP LQ+KMR +LR+EVEAV+FLKEEP +LD LLKR R VT
Sbjct: 728 EAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVT 787
Query: 820 DTL------AQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFNKS-----VDFEMPPPS-- 866
D L AQ + + L SQ T+ F+ + E+ P S
Sbjct: 788 DGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGM 847
Query: 867 -----------------------PPLNL-HELSGPAEGASLT--------------PKGG 888
P NL H S PA T P G
Sbjct: 848 MVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNG 907
Query: 889 NPTKGLDTPGKRSV---DKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAI 945
+ + L SV ++AVS+E AE+ WEEKR L Y+ K+ +LLEE QA ++K+I
Sbjct: 908 SAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSI 967
Query: 946 PDLDCASKAHPGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPP 1005
P+L+ GP P D AP + P+ + ++L S PP
Sbjct: 968 PNLEMPPAT--GPLPRGD-----APVDKVELSEDSPNSEQDLEKL-------GGKSPPPP 1013
Query: 1006 PPPPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARP 1065
PPPPRRS+ GLTTTR+G+VV T +K++ KA SE+ PQ + + +E
Sbjct: 1014 PPPPRRSYLPGSGLTTTRSGDVVYTGRKEN-ITAKASSEDAG-PSPQTRATKYPAEEPAS 1071
Query: 1066 A---STPPIMASAIKDEDDE----DRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGS 1118
A S PP+ S+ KDE++E D+I+AEL+ G+ ++ P +A+ + G+
Sbjct: 1072 AWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVP-----MSAKNRPGT 1126
Query: 1119 PDKSKHGKQRAEYMRIQAQQQATKPSKEMSGSNETSSPVSEKPSASRTSIPVLTSFGARN 1178
DK GKQ ++ + +QA +K+ G + +S PS + IP L+ ++
Sbjct: 1127 LDKP--GKQ-SKLQDPRQYRQANGSAKKSGGDFKPTS-----PSLPASKIPALSPSSGKS 1178
Query: 1179 SSI 1181
SS+
Sbjct: 1179 SSL 1181
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 63.9 bits (154), Expect = 9e-10
Identities = 98/389 (25%), Positives = 136/389 (34%), Gaps = 79/389 (20%)
Query: 289 SPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHA 348
SP R L PAP A PPP +G S +P + + A G P+ AG P A
Sbjct: 109 SPRRPLVPAGPAPPAAKLRPPPEGSAG------SCAPVPAAAAVAAGPEPAPAG-PAKPA 161
Query: 349 AERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKA--GGMVLVKGEGLYADPYGLLHEG 406
A A G P P KP A++ G L+ A L++ G
Sbjct: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
Query: 407 RLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGY 466
+L P P A G +++ AAA + S
Sbjct: 222 PAALL-----PLPKPAAPGTV----IQTPPFVGAAAPPAPAAPS---------------- 256
Query: 467 GFRLPPSSPQKLADVAAPPGGPP-------PPHSPYSGPPSRGSPVRQSFRKDSGSSSVF 519
PP++P A AAPP PP PP P +GPP+ V +G S+
Sbjct: 257 ----PPAAPAPAAPAAAPPPPPPAPATLARPPGHP-AGPPTAAPAVPPPAAAQNGGSAGA 311
Query: 520 AESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIAS 579
A +P + G A +G PGPG + P P E+ +R
Sbjct: 312 APAPA--PAAGGPAGVSGQ------PGPGAAA----AAPAPGVKAESPKR---------- 349
Query: 580 LTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPA 639
+VQ+A P+ + ++G A+ +A G GA P PP A TP
Sbjct: 350 ---VVQAA--------PPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPT 398
Query: 640 GQPTAVSRLQMQLHLRGLQNSASDLRGQL 668
G P + Q R + S +R L
Sbjct: 399 GLPKGAAGAVTQSLSRTPTATTSGIRATL 427
Score = 33.9 bits (76), Expect = 0.94
Identities = 18/59 (30%), Positives = 24/59 (40%)
Query: 591 GSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQ 649
G+ P+ EG+ GAA P G G GPP P PAG ++L+
Sbjct: 69 GAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLR 127
>gi|110611914 progesterone receptor [Homo sapiens]
Length = 933
Score = 60.5 bits (145), Expect = 9e-09
Identities = 104/376 (27%), Positives = 133/376 (35%), Gaps = 46/376 (12%)
Query: 286 RESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPV 345
R SP R+L L PA S P PS + ++ S + G P G P
Sbjct: 187 RGLSPARQL--LLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAG--PLLKGKP- 241
Query: 346 HHAAERLGGAPAAQGVSP-SPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLH 404
LGGA A G + P A + P ED A + LV+ + A
Sbjct: 242 ----RALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAP------ 291
Query: 405 EGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLS-TYSAAALQSDLEDSLYKAAGGGGPLYG 463
GR LA D P + L+ AA + LED Y G
Sbjct: 292 -GRSPLATTVMDFIHVP----------ILPLNHALLAARTRQLLEDESYDGGAGAAS--- 337
Query: 464 DGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESP 523
F P SSP + A P + P + P P+ F+ + E
Sbjct: 338 ---AFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGA 394
Query: 524 GGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGL 583
RS S AGA P+ P +G PP+P + T +R A+ AS +
Sbjct: 395 EASARSPRSYLVAGANPAAFPDFP-----LGPPPPLPPRATPSRPGEAAVTAAPASAS-- 447
Query: 584 VQSALLRGSEPETPSEKIEGSNGAATPSAP--CGSGGRSSGATPVSGPPPPSASSTPAGQ 641
V SA GS E K EG+ P AP C + G S P G P SAS+ AG
Sbjct: 448 VSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAG- 506
Query: 642 PTAVSRLQMQLHLRGL 657
A L L L GL
Sbjct: 507 --AAPALYPALGLNGL 520
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 56.2 bits (134), Expect = 2e-07
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 50/207 (24%)
Query: 470 LPPSSPQKLADVAAPPG-GPPPPHSPYSGPPS---RGSPVRQSFRKDSGSSSVFAESPGG 525
LP S+P + PP PPPP +P S PP+ G P S +D +SV A S GG
Sbjct: 289 LPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPPEDSS--QDLAPNSVGAASTGG 346
Query: 526 KT----RSAGSASTA------GAPPSE----------LFPGPGERSLVGFGPPVPAKDTE 565
T + +A+TA G PS PG G+RSLVG +
Sbjct: 347 GTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVG-------SEGL 399
Query: 566 TRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATP 625
++E++E E+ + +L ++ LLR E E P GG G P
Sbjct: 400 SKEQLEHRERSLQTLRD-IERLLLRSGETE--------------PFLKGPPGGAGEGGPP 444
Query: 626 VSGPPPPSASSTPAGQPTAVSRLQMQL 652
PPPP P P+ + + + L
Sbjct: 445 AQAPPPP--QQPPTAPPSGLKKYEEPL 469
Score = 35.0 bits (79), Expect = 0.42
Identities = 44/194 (22%), Positives = 72/194 (37%), Gaps = 9/194 (4%)
Query: 454 AAGGGGPL-----YGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQS 508
+A GPL G R P SP +L + P SP + PS G +
Sbjct: 966 SANPPGPLKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQ 1025
Query: 509 FRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSL--VGFGPPVPAKDTET 566
+ SS+ + G +G S++ APP+ G SL P P+++ +
Sbjct: 1026 PPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLS 1085
Query: 567 RERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPV 626
+ + + S T L +A+ + + E + P P GSG S + P
Sbjct: 1086 LMMTQMSKYAMPSSTPLYHNAI--KTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPS 1143
Query: 627 SGPPPPSASSTPAG 640
+A+ +P G
Sbjct: 1144 QMHLNSAAAQSPMG 1157
Score = 32.0 bits (71), Expect = 3.6
Identities = 54/211 (25%), Positives = 71/211 (33%), Gaps = 63/211 (29%)
Query: 297 LSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAP 356
L P P A GS PP LP G P S A P+ G AA GG
Sbjct: 306 LPPPPPPAPGSAPPALP-------PEGPPEDSSQDLA----PNSVG-----AASTGGG-- 347
Query: 357 AAQGVSP-SPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAG 415
G P +P+A + P D +S G +L GE AA
Sbjct: 348 -TGGTHPNTPTATTANNPLPPGGDPSSAPGPALL--GEA----------------AAPGN 388
Query: 416 DPFAYPGAGGL------YKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFR 469
+ G+ GL ++ S+++L L+S + K GG G+G
Sbjct: 389 GQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGA---GEG---- 441
Query: 470 LPPSSPQKLADVAAPPGGPPPPHSPYSGPPS 500
P PPPP P + PPS
Sbjct: 442 ------------GPPAQAPPPPQQPPTAPPS 460
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 54.3 bits (129), Expect = 7e-07
Identities = 59/199 (29%), Positives = 72/199 (36%), Gaps = 30/199 (15%)
Query: 456 GGGGPLYGDGYGFRLPPSSPQKLAD--VAAPPG-----GPPPPHSPYSGPPSRGSPVRQS 508
G GP+ G R PP P K D A PG GPP P P + G P +
Sbjct: 212 GASGPM-----GPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKG 266
Query: 509 FRKDSGSSSVFAES-PGGKTRSAGSASTAGAPPSELFPG--PGERSLVGFGPPVPAKDTE 565
R SG ++ P G GS GAP ++ P PGER G P A+ +
Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP-GQMGPRGLPGERGRPGAPGPAGARGND 325
Query: 566 TRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATP 625
TG G G+ G A P P GS G G
Sbjct: 326 -------------GATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEG-PQGVRG 371
Query: 626 VSGPPPPSASSTPAGQPTA 644
GPP P+ ++ PAG P A
Sbjct: 372 EPGPPGPAGAAGPAGNPGA 390
Score = 48.5 bits (114), Expect = 4e-05
Identities = 55/193 (28%), Positives = 67/193 (34%), Gaps = 31/193 (16%)
Query: 467 GFRLP-PSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGG 525
G +P P P + PPG P P + GPP G P G P G
Sbjct: 174 GISVPGPMGPSGPRGLPGPPGAPGP--QGFQGPP--GEPGEPGASGPMGPRG--PPGPPG 227
Query: 526 KTRSAGSASTAGAPPSELFPGP-GERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLV 584
K G A G P PGP G R L G K + + L G
Sbjct: 228 KNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKG----------HRGFSGLDGAK 277
Query: 585 QSALLRG--SEPETPSEK----------IEGSNGAATPSAPCGSGGRSSGATPVSGPPPP 632
A G EP +P E + G G P G+ G + GAT +GPP P
Sbjct: 278 GDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARG-NDGATGAAGPPGP 336
Query: 633 SASSTPAGQPTAV 645
+ + P G P AV
Sbjct: 337 TGPAGPPGFPGAV 349
Score = 47.4 bits (111), Expect = 8e-05
Identities = 99/394 (25%), Positives = 129/394 (32%), Gaps = 84/394 (21%)
Query: 304 ASGSPPPGLPSGLP-SGLQSGSPSRSR---LSYAGGRP--PSYAGSPVHHAAERLGGAPA 357
A G P P G P S ++G+P + L GRP P AG+ + A G P
Sbjct: 276 AKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG 335
Query: 358 AQGVSPSPS---AILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAA 414
G + P A+ + + P S+ G V+GE P G A A
Sbjct: 336 PTGPAGPPGFPGAVGAKGEAGPQGPRGSE--GPQGVRGEPGPPGPAGA--------AGPA 385
Query: 415 GDPFA--YPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPP 472
G+P A PGA G + + A S + G GGP G P
Sbjct: 386 GNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ-------GPGGPPGPKGNSGE--P 436
Query: 473 SSPQKLADVAA-----------PPG-----------------GPPPPHSPYSGPPSRGSP 504
+P D A PPG G P P GP SRG P
Sbjct: 437 GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFP 496
Query: 505 VRQSFRKDSGSSSVFA-ESPGGKTRSAGSASTAGAPPSELFPG----PGERSLVG----- 554
G+ V + P G+ S G A G+P PG PG + L G
Sbjct: 497 ---------GADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSP 547
Query: 555 -----FGPPVPA-KDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAA 608
GPP PA +D + A + G G + + G GA
Sbjct: 548 GPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAV 607
Query: 609 TPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQP 642
P+ G G + G +GP PAG P
Sbjct: 608 GPAGKDGEAG-AQGPPGPAGPAGERGEQGPAGSP 640
Score = 47.4 bits (111), Expect = 8e-05
Identities = 91/364 (25%), Positives = 120/364 (32%), Gaps = 75/364 (20%)
Query: 301 PHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGR-------PPSYAGSPVHHAAERLG 353
P + + PPG P P+G + G R AG PP AG A+
Sbjct: 886 PGPSGNAGPPGPPG--PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPA 943
Query: 354 GAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAA 413
GAP +P P I +R V G+ +GE G L
Sbjct: 944 GAPG----TPGPQGIAGQRGVV----------GLPGQRGE-----------RGFPGLPGP 978
Query: 414 AGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPS 473
+G+P +G +RG + A E A G G DG
Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPG--ESGREGAPGAEGSPGRDG-------- 1028
Query: 474 SPQKLAD-----VAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTR 528
SP D A PPG P P +P GP G + R ++G + P G
Sbjct: 1029 SPGAKGDRGETGPAGPPGAPGAPGAP--GPV--GPAGKSGDRGETGPAG--PAGPVGPVG 1082
Query: 529 SAGSASTAGAPPSELFPGP-GERSLVGF-------GPPVPAKDTETRERMEAMEKQIASL 580
+ G A G + G G+R + G GPP P +
Sbjct: 1083 ARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQ-----------GP 1131
Query: 581 TGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAG 640
+G A RG + +G NG P P G GR+ A PV P PP P G
Sbjct: 1132 SGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG-PPG 1190
Query: 641 QPTA 644
P+A
Sbjct: 1191 PPSA 1194
Score = 45.1 bits (105), Expect = 4e-04
Identities = 90/359 (25%), Positives = 118/359 (32%), Gaps = 58/359 (16%)
Query: 299 PAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAA 358
P P A+G P G+P + P+ PP AG + G+P
Sbjct: 583 PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF 642
Query: 359 QGVSPSPSAILERRDVKPDEDLASKAG--------------GMVLVKGEGLYADPYGLLH 404
QG+ P P+ ++ + G G V+G A P G
Sbjct: 643 QGL-PGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGA-- 699
Query: 405 EGRLSLAAAAGDPFAYPGAGGLYKRGSVRSL-STYSAAALQSDLEDSLYKAAGGGGPLYG 463
G A GD A PGA G ++ + AA L D G GP
Sbjct: 700 NGAPGNDGAKGDAGA-PGAPGSQGAPGLQGMPGERGAAGLPGPKGD-----RGDAGPKGA 753
Query: 464 DGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESP 523
DG SP K D GP P P P +G +SG S P
Sbjct: 754 DG--------SPGK--DGVRGLTGPIGPPGPAGAPGDKG---------ESGPS-----GP 789
Query: 524 GGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGL 583
G T + G+ G P PGP GF P P D + + E + G
Sbjct: 790 AGPTGARGAPGDRGEPGP---PGP-----AGFAGP-PGADGQPGAKGEPGDAGAKGDAGP 840
Query: 584 VQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQP 642
A G + G+ GA + P G+ G GA GPP PS ++ P G P
Sbjct: 841 PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG-FPGAAGRVGPPGPSGNAGPPGPP 898
Score = 40.0 bits (92), Expect = 0.013
Identities = 49/197 (24%), Positives = 66/197 (33%), Gaps = 18/197 (9%)
Query: 454 AAGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDS 513
A G GP G+ P + A PP GPP P G RG +
Sbjct: 864 ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP-GPPGPAGKEGGKGPRGETGPAGRPGEV 922
Query: 514 GSSSVFAESPGGKTRSAGSASTAGAPPSELFPGP----GERSLVGFG--------PPVPA 561
G P G+ S G+ AGAP + PGP G+R +VG P +P
Sbjct: 923 GPPG--PPGPAGEKGSPGADGPAGAPGT---PGPQGIAGQRGVVGLPGQRGERGFPGLPG 977
Query: 562 KDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSS 621
E ++ + G + L G E+ E G+ G+ G+ G
Sbjct: 978 PSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG 1037
Query: 622 GATPVSGPPPPSASSTP 638
P P P A P
Sbjct: 1038 ETGPAGPPGAPGAPGAP 1054
>gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo
sapiens]
Length = 669
Score = 54.3 bits (129), Expect = 7e-07
Identities = 87/352 (24%), Positives = 134/352 (38%), Gaps = 56/352 (15%)
Query: 486 GGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFP 545
GGP S S + P+ S S ++S S + ST GA P+ P
Sbjct: 184 GGPASSSSSSSSSSAADKPLAFSGWASGCPSGTLSDSGRNSLSSLPTYSTGGAEPTTSSP 243
Query: 546 -------GPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPS 598
G G +L G VP + + + K SL G V LL
Sbjct: 244 GGHLPSHGSGRGALPGPARGVPTGPSHSDSGRSSSSKSTGSLGGRVAGGLL--------- 294
Query: 599 EKIEGSNGAATP-SAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQMQLHLRGL 657
GS A+P S+ CG +P PPPPS A+ ++ LR
Sbjct: 295 ----GSGTRASPDSSSCGE------RSPPPPPPPPS--------DEALLHCVLEGKLRDR 336
Query: 658 QNSASDLRGQLQQLRKLQLQ-NQESVRALLKRTEA--ELSMRVSEAARRQEDPLQRQRTL 714
+ LR L + Q +E R + EA E ++ A+R + LQ Q
Sbjct: 337 EAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQAQRAQRAQQLLQLQVFQ 396
Query: 715 VEEERLRYLNDEELITQQLNDLEK---SVEKIQRDVSHNHRLVPGPELEEKALVLKQLGE 771
+++E+ + +D + Q+ LE+ ++E+ QR++ GP LEE + Q
Sbjct: 397 LQQEKRQLQDDFAQLLQEREQLERRCATLEREQREL--------GPRLEETKWEVCQKSG 448
Query: 772 TLTELKAHFPGLQSKM------RVVLRVEV-EAVKFLKEEPQRLDGLLKRCR 816
++ LK Q+++ V LRV + EA L+ R GL + R
Sbjct: 449 EISLLKQQLKESQAELVQKGSELVALRVALREARATLRVSEGRARGLQEAAR 500
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 53.9 bits (128), Expect = 9e-07
Identities = 209/986 (21%), Positives = 327/986 (33%), Gaps = 153/986 (15%)
Query: 287 ESSPTRRLNNLSPAPHLASGSPPPGLPSGLP---SGLQSGSPSRSRLSYAGGRPPSYAGS 343
ESSP L + +P+ H SGS PP + S P S +S SP + R S++GS
Sbjct: 874 ESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS 933
Query: 344 PVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLL 403
+ + S SP + +E R + P + + VK E P
Sbjct: 934 SSPSPSRVTSRTTPRRSRSVSPCSNVESR-LLPRYSHSGSSSPDTKVKPE----TPPRQS 988
Query: 404 HEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYG 463
H G +S YP G SLS + Q +DSL ++ G L
Sbjct: 989 HSGSIS---------PYPKVKAQTPPGP--SLSGSKSPCPQEKSKDSLVQSCPGSLSLCA 1037
Query: 464 DGYGFRLPP-----------------SSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVR 506
G PP +SP +D ++P SP S+ SP
Sbjct: 1038 -GVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKG 1096
Query: 507 QSFRKDSGSSSVFAESPGGKTRSAGSAST---AGAPP--------SELFPGPGERSLVGF 555
R S + + + SP + R SAS +G P S +P SL+G
Sbjct: 1097 GRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQ 1156
Query: 556 GPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSE-PETPSEKIEGSNGAATPSAPC 614
+ E++E+M ++ A+ + Q + P + + TP
Sbjct: 1157 SR---LETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER 1213
Query: 615 GSGGRSSGATPVSGPPPPSA-----------SSTPAGQPTAVSRLQMQLHLRGLQNSASD 663
G S + P S+ S PAGQ +S L +L N S
Sbjct: 1214 SGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQ--ILSHLSSELKEMSTSNFESS 1271
Query: 664 LRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVS--------EAARRQEDPLQRQRTLV 715
+ + L L +S +A L+ E SM S E PL+
Sbjct: 1272 PEVEERPAVSLTLDQSQS-QASLEAVEVP-SMASSWGGPHFSPEHKELSNSPLRENSF-- 1327
Query: 716 EEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGETLTE 775
L + N L T+ V++ N +L P L+ K + G + +E
Sbjct: 1328 -GSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLN-QLETDPSLDMKEQSTRSSGHSSSE 1385
Query: 776 L------KAHFPGLQSKMRVVL----RVEVEAVKFLKEEPQRLDGL----LKRCR----- 816
L KA QS VL R P+ DGL +R R
Sbjct: 1386 LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSP 1445
Query: 817 GVTDTLAQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFNKSVDF--------EMPPPSPP 868
G+ D R G P ++ ++P + +E D + P SP
Sbjct: 1446 GLRDGSGTPSRHSLSGSSPGMKDI-PRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504
Query: 869 LNLHELSGPAEGASLTPKGGNPTKGLDTPGKRS-------VDKAVSVEAAERDWEEKRAA 921
LN L+ E + T G+RS +D S ER +
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSP- 1563
Query: 922 LTQYSAKDINRLLEETQAELLKAIPDLDCASKAHP-----GPAPTPDHKPPKAPHGQ--- 973
AK L + +++ + P++D S+ P G +P KP AP Q
Sbjct: 1564 --DSKAKTRTPLRQRSRSG---SSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGS 1618
Query: 974 -----------KAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTTT 1022
+A PR SG P + S PP R + S
Sbjct: 1619 DSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEP 1678
Query: 1023 RTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKDEDDE 1082
+T ++ S P++ + +S +R AS+ P S
Sbjct: 1679 KTKSRTPPRRRSSR------------SSPELTRKARLSRRSRSASSSPETRSRTPPRHRR 1726
Query: 1083 DRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQAQQQATK 1142
++ E S + + + R K + SP G QR+ R + ++ T
Sbjct: 1727 SPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR-SRSRREKTRTT 1785
Query: 1143 PSKEMSGSNETSSPVSEKPSASRTSI 1168
++ SGS++++S ++ S SR+ +
Sbjct: 1786 RRRDRSGSSQSTSRRRQR-SRSRSRV 1810
Score = 50.8 bits (120), Expect = 7e-06
Identities = 74/299 (24%), Positives = 102/299 (34%), Gaps = 47/299 (15%)
Query: 322 SGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLA 381
SG S L A R P A S +ER + G +PS S + +D +P +
Sbjct: 2394 SGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD-QPRSPVP 2452
Query: 382 SK---------------AGGMVLVKGEGLYADPYGLLHEGRLSLAAAA------GDPFAY 420
S AG L G H G LS+ A G+P A
Sbjct: 2453 SAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAS 2512
Query: 421 PGA------GGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSS 474
GA L RS S+ S+++ S S ++ G D G LP
Sbjct: 2513 TGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQP 2572
Query: 475 PQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSAS 534
L V +P P P + G P +P ++ R S SSS + S + S+ S+S
Sbjct: 2573 EVALKRVPSPT--PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 535 TAGAP-------------PSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASL 580
++ + PS PGP P P K R + K I SL
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALP----KPASPKKPPPGERRSRSPRKPIDSL 2685
Score = 47.8 bits (112), Expect = 6e-05
Identities = 198/943 (20%), Positives = 306/943 (32%), Gaps = 151/943 (16%)
Query: 285 SRESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQS-GSPSRSRLSYAGGRPPSYAGS 343
S S P ++ + +S SP P + SG P S SP + S R + S
Sbjct: 817 SSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
Query: 344 PVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLL 403
P R + G SP + P + + + VK P
Sbjct: 877 PDPELKSRTPSRHSCSGSSPPRV----KSSTPPRQSPSRSSSPQPKVKA---IISPRQRS 929
Query: 404 HEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSL---YKAAGGGGP 460
H G S P + R + R + S S++E L Y +G P
Sbjct: 930 HSGSSS-----------PSPSRVTSRTTPRRSRSVSPC---SNVESRLLPRYSHSGSSSP 975
Query: 461 LYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGS--PVRQSFRKDSGSSSV 518
++ P +P + + + P GP GS P Q KDS +
Sbjct: 976 ------DTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDS----L 1025
Query: 519 FAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTET------RERMEA 572
PG + AG S+ PP E + G L G P ++T + E+
Sbjct: 1026 VQSCPGSLSLCAGVKSST--PPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSES 1083
Query: 573 MEKQIASLTGLVQSALLRGSEPETP---SEKIEGSNG--AATPSAPCGSGGRSSGATPVS 627
Q S T + R S P T I G +A+P G S S
Sbjct: 1084 PSLQSKSQTS-PKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDS 1142
Query: 628 GPPPPSASSTPAGQP---TAVSRLQMQLHLRGLQNSASDLRGQLQQLRKLQLQNQESVRA 684
P S++ GQ TA S+ +M L + +++ + Q + +Q++
Sbjct: 1143 SSYPTVDSNSLLGQSRLETAESKEKMALPPQ--EDATASPPRQKDKFSPFPVQDRPESSL 1200
Query: 685 LLKRTEAELSMRVSEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEKIQ 744
+ K T S A E Q + DEEL + +EKS E
Sbjct: 1201 VFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQ------DEEL----MEVVEKSEEPAG 1250
Query: 745 RDVSH---------NHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEV 795
+ +SH PE+EE+ V L ++ ++ + S +
Sbjct: 1251 QILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPS-----MASSW 1305
Query: 796 EAVKFLKEEPQRLDGLLKRCRGVTDTLAQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFN 855
F E + + L+ E + P + P T F+
Sbjct: 1306 GGPHFSPEHKELSNSPLR-----------------ENSFGSPLEFRNSGPLGTEMNTGFS 1348
Query: 856 KSVDFEMPPP-------SPPLNLHELSGPAEGASLTPKGGNPTKGLDTPGKRSVDKAVSV 908
V ++ P P L++ E S + G S + + + +S+ V
Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLD 1408
Query: 909 EAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAHPG---PAPTPD-H 964
E+ ++ + KD L P S + PG + TP H
Sbjct: 1409 AVPRTPSRERSSSASSPEMKDG-----------LPRTPSRRSRSGSSPGLRDGSGTPSRH 1457
Query: 965 KPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTT--- 1021
+ G K PRT GR D + +P P P PR PSS L
Sbjct: 1458 SLSGSSPGMKDIPRTPSRGRSECDS-------SPEPKALPQTPRPRSRSPSSPELNNKCL 1510
Query: 1022 ----TRTGEVVVTSKKDSAFI------KKAESEELEVQ---KPQVKLRRAVSEVARPAST 1068
R+G +K A + S+EL+V+ PQ + S ++ +
Sbjct: 1511 TPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTR 1570
Query: 1069 PPI---MASAIKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPD-KSKH 1124
P+ S E D ++ S GS P +K A R A G SP+ K+
Sbjct: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR--AQSGSDSSPEPKAPA 1628
Query: 1125 GKQRAEYMRIQAQQQATKPSKEMSGSNETSSPVSEKPSASRTS 1167
+ R + + PS E S S E+S E P SRT+
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESS---PEHPPKSRTA 1668
Score = 43.5 bits (101), Expect = 0.001
Identities = 43/179 (24%), Positives = 65/179 (36%), Gaps = 5/179 (2%)
Query: 463 GDGYGFRLPPSSPQKLADVAAPPG--GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFA 520
GD G P+ +DV PP G P + + P++ R+S S SSS +
Sbjct: 2488 GDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE---RRSSSSSSSSSSSSS 2544
Query: 521 ESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASL 580
S + S+ S S++ P E +L P PA RE
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604
Query: 581 TGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPA 639
S+ S + S S+ +++ S+ S SS ++P P P A PA
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA 2663
Score = 37.4 bits (85), Expect = 0.085
Identities = 59/296 (19%), Positives = 93/296 (31%), Gaps = 34/296 (11%)
Query: 882 SLTPKGGNPTKGLDTPGKRSVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAEL 941
S TPK +K RS A A R A+ + S +T
Sbjct: 231 SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTA 290
Query: 942 LKAIPDLDCASKAHPGPAP------TPDHKP--PKAPHGQKAAPRTEPSGRRGSDELTVP 993
L + + G AP T +P P+ Q ++P + + T P
Sbjct: 291 LAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP 350
Query: 994 RYRTEKPSKSPPPPPPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQV 1053
E+ S P PP P HG + ++ + + + + + + K
Sbjct: 351 SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPE 410
Query: 1054 KLRRAVSEVARPASTPPIMASAIKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQ 1113
KL ++ S + P S P S E P PG+ R
Sbjct: 411 KLPQSSSSESSPPSPQPTKVSRHASSSPES--------------PKPAPAPGSHR----- 451
Query: 1114 GQAGSPDKSKHGKQRAEYMRIQAQQQATKPSKEMSGSNETSSPVSEKPSASRTSIP 1169
+ SP RA+ + + + PS+ M S SP + K SR+ P
Sbjct: 452 EISSSPTSKNRSHGRAK----RDKSHSHTPSRRMGRSR---SPATAKRGRSRSRTP 500
Score = 37.4 bits (85), Expect = 0.085
Identities = 62/274 (22%), Positives = 99/274 (36%), Gaps = 44/274 (16%)
Query: 916 EEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAHPGPAPTPD---------HKP 966
++ RAA S D + E +A +A+P + + G P+P+ P
Sbjct: 1606 DKPRAAPRAQSGSDSS---PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662
Query: 967 PK---APHGQKAAP------RTEPSGR--RGSDELTVPRYRTEKPSKSPPPPPPRRSFPS 1015
PK A G +++P RT P R R S ELT + R + S+S P RS
Sbjct: 1663 PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT-RKARLSRRSRSASSSPETRS--- 1718
Query: 1016 SHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKL--RRAVSEVARPASTPPIMA 1073
T R S + A ++ P+ K RR S +P +
Sbjct: 1719 ---RTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG---LQR 1772
Query: 1074 SAIKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMR 1133
S + ++ R + G S + SR + + + G + R
Sbjct: 1773 SRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS---------GYHSR 1823
Query: 1134 IQAQQQATKPSKEMSGSNETSSPVSEKPSASRTS 1167
A+Q++++ S + P S K S SRTS
Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857
Score = 35.8 bits (81), Expect = 0.25
Identities = 21/65 (32%), Positives = 26/65 (40%)
Query: 469 RLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTR 528
R PP SP+KL ++ PP P + SP GS + SP K R
Sbjct: 403 RSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNR 462
Query: 529 SAGSA 533
S G A
Sbjct: 463 SHGRA 467
Score = 35.4 bits (80), Expect = 0.32
Identities = 116/577 (20%), Positives = 185/577 (32%), Gaps = 55/577 (9%)
Query: 457 GGGPLYGDGYGFRLPPSSPQK---LADVAAPPG-GPPPPHSPYSGPPSRGSPVRQSFRKD 512
G GP D +P + Q LA A G PPP +G +R
Sbjct: 2159 GPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR----------- 2207
Query: 513 SGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEA 572
S V A P R+A +A+ A P+ S P ++R A
Sbjct: 2208 --MSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAA 2265
Query: 573 MEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPP 632
+AS V + + ++P TP+ GA TP+A SG TP + P
Sbjct: 2266 AAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSG-TPPTAANYP 2324
Query: 633 SASSTPAGQPTA------VSRLQMQLHLRGLQNSASDLRGQLQQLR---KLQLQNQESVR 683
S+S TP +A + +++ G + +A+ L R L N S R
Sbjct: 2325 SSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPR 2384
Query: 684 ALL---KRTEAELSMRVSEAARRQEDP-------LQRQRTLVEEERLRYLNDEELITQQL 733
L +R S + + AR + P + +R R+ + L+
Sbjct: 2385 VPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQ 2444
Query: 734 NDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRV 793
+ V D S P ++L + T + H L V
Sbjct: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
Query: 794 EVEAVKFLKEEPQRLDGLLKRCRGVTDTLAQIRRQVDEGVWPPPNNLLSQSPKKVTAETD 853
+V EP G + A+ RR ++ S S ++ +
Sbjct: 2505 DV-------GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSG 2557
Query: 854 FNKSVDFEMPPPSPP-LNLHELSGPAEGASLTPKGGNPTKGLDTPGKRSVDKAVSVEAAE 912
+ S P P + L + P + G P + TP KR + S ++
Sbjct: 2558 SSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE--PTPAKRKRRSSSSSSSSS 2615
Query: 913 RDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAHPGPAPTPDHKPPKAP-- 970
++ + S+ + + + + P S A PGP P PK P
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP-----SPAKPGPQALPKPASPKKPPP 2670
Query: 971 -HGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPP 1006
+ +PR R S L+ +PS P P
Sbjct: 2671 GERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
Score = 30.8 bits (68), Expect = 8.0
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 13/88 (14%)
Query: 286 RESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSP---SRSRLSYAGGRPPSYAG 342
+E S TR SP+P +S P P P+ L + GSP + + LS PPS A
Sbjct: 343 KEKSATRP----SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEA- 397
Query: 343 SPVH-----HAAERLGGAPAAQGVSPSP 365
SP + E+L + +++ PSP
Sbjct: 398 SPTRDRSPPKSPEKLPQSSSSESSPPSP 425
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 53.1 bits (126), Expect = 2e-06
Identities = 99/384 (25%), Positives = 125/384 (32%), Gaps = 70/384 (18%)
Query: 298 SPAPHLASGSPPPGLPSGL--PSGLQS--GSPSRSRLSYAGGR--PPSYAGSPV------ 345
+P P SG+P P P+G+ P G + G P + A GR PP G+P
Sbjct: 862 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921
Query: 346 ------------HHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGE 393
G P QG + P E D P G L
Sbjct: 922 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPS-GAEGPPGPQGLAGQR 980
Query: 394 GLYADPYGLLHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYK 453
G+ P G L +G+P G RG + E
Sbjct: 981 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAG--EPGREG 1038
Query: 454 AAGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDS 513
+ G GP DG + PG P PP SP GP G +Q R ++
Sbjct: 1039 SPGADGPPGRDGAA---GVKGDRGETGAVGAPGAPGPPGSP--GPA--GPTGKQGDRGEA 1091
Query: 514 GSSSVFAESPGGKTRSAGSASTAGAPPSELFPG----PGERSLVGF----------GPPV 559
G A+ P G + AG+ G G PGER L G GPP
Sbjct: 1092 G-----AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1146
Query: 560 PAKDTETRERMEAMEKQIASLTGLVQSALLRGSE-PETPSEKIEGSNGAATPSAPCGSGG 618
P+ D +G + RG P PS K +G+NG P P G G
Sbjct: 1147 PSGDQ--------------GASGPAGPSGPRGPPGPVGPSGK-DGANGIPGPIGPPGPRG 1191
Query: 619 RSSGATPVSGPPPPSASSTPAGQP 642
R SG T +GPP P G P
Sbjct: 1192 R-SGETGPAGPPGNPGPPGPPGPP 1214
Score = 47.0 bits (110), Expect = 1e-04
Identities = 94/387 (24%), Positives = 128/387 (33%), Gaps = 70/387 (18%)
Query: 298 SPAPHLASGSP-PPGLPSGLPSGLQSGSPSRSRLSYAGGR-----------PPSYAGSPV 345
+P P G P PPGL + + G ++ + G PP AG+P
Sbjct: 160 NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219
Query: 346 HHAAERLGGAPAAQGVS--------PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYA 397
+ G P GVS P P KP +D + G GE
Sbjct: 220 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPG-------KPGDDGEAGKPGKA---GERGPP 269
Query: 398 DPYGLL-HEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAG 456
P G G L G YPG G + S + ++ G
Sbjct: 270 GPQGARGFPGTPGLPGVKGHR-GYPGLDGAKGEAGAPGVKGESGSPGEN----------G 318
Query: 457 GGGPLYGDGYGFRLPPSSPQKLA-----DVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRK 511
GP+ G + P A D P GPP P P GP G+P +
Sbjct: 319 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 378
Query: 512 DSGS-SSVFAESPGGKTRSAGSASTAGA---PPSELFPG-------PGERSLVGF----G 556
+G+ A+ P G+ + GS AGA P ++ PG PG GF G
Sbjct: 379 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 438
Query: 557 PPVPAKDT-ETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCG 615
PP P T + + E IA G +G + E +G+ G A G
Sbjct: 439 PPGPQGATGPLGPKGQTGEPGIAGFKG------EQGPKGEPGPAGPQGAPGPAGEEGKRG 492
Query: 616 SGGRSSGATPVSGPPPPSASSTPAGQP 642
+ G G P+ GPP + G P
Sbjct: 493 ARGEPGGVGPI-GPPGERGAPGNRGFP 518
Score = 47.0 bits (110), Expect = 1e-04
Identities = 98/374 (26%), Positives = 121/374 (32%), Gaps = 55/374 (14%)
Query: 299 PAPHLASGSPPPGLPSGLPS--GLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAP 356
P P A+G P GLP GL+ G P + + A G PP AG + G
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLR-GLPGKDGETGAAG-PPGPAGPAGERGEQGAPGPS 662
Query: 357 AAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGD 416
QG+ P P D+ + +AG LV G P G L G
Sbjct: 663 GFQGL-PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 721
Query: 417 PFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDG-YGFRLPPSSP 475
P G G LQ + AAG GP G G + P +P
Sbjct: 722 PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER--GAAGIAGPKGDRGDVGEKGPEGAP 779
Query: 476 QK-----LADVAAPPG--------GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAES 522
K L PPG G P P +RG+P + G + FA
Sbjct: 780 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG-FAGP 838
Query: 523 PG--------GKTRSAGSASTAGAP-PSELFPGPGERSLVGFGPPVPAKDTETRERMEAM 573
PG G+ AG AGAP P PG + G P A+ +
Sbjct: 839 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP----- 893
Query: 574 EKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRS--SGATPVSGPPP 631
TG +A G GSNG P P G G+ GA SGPP
Sbjct: 894 -----GATGFPGAAGRVGPP---------GSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 939
Query: 632 PSAS---STPAGQP 642
+ PAG P
Sbjct: 940 RAGEPGLQGPAGPP 953
Score = 36.6 bits (83), Expect = 0.15
Identities = 60/226 (26%), Positives = 72/226 (31%), Gaps = 50/226 (22%)
Query: 456 GGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGS 515
G GP DG P +P PPG P PP P G K G+
Sbjct: 144 GAPGPRGRDG-----EPGTPGN----PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGA 194
Query: 516 SSVFAESPGGKTRSAGSASTAGAPPSELFPG----PGERSLVG----FGPP----VPAKD 563
+ P G G AGAP + F G PGE + G GPP P D
Sbjct: 195 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDD 254
Query: 564 TETRERMEAME---------KQIASLTGLVQSALLRG--------SEPETPSEKIE---- 602
E + +A E + GL RG E P K E
Sbjct: 255 GEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP 314
Query: 603 GSNGAATPSAPCGSGGR--------SSGATPVSGPPPPSASSTPAG 640
G NG+ P P G G ++GA G P P+ P G
Sbjct: 315 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 360
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 53.1 bits (126), Expect = 2e-06
Identities = 99/384 (25%), Positives = 125/384 (32%), Gaps = 70/384 (18%)
Query: 298 SPAPHLASGSPPPGLPSGL--PSGLQS--GSPSRSRLSYAGGR--PPSYAGSPV------ 345
+P P SG+P P P+G+ P G + G P + A GR PP G+P
Sbjct: 793 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852
Query: 346 ------------HHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGE 393
G P QG + P E D P G L
Sbjct: 853 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPS-GAEGPPGPQGLAGQR 911
Query: 394 GLYADPYGLLHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYK 453
G+ P G L +G+P G RG + E
Sbjct: 912 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAG--EPGREG 969
Query: 454 AAGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDS 513
+ G GP DG + PG P PP SP GP G +Q R ++
Sbjct: 970 SPGADGPPGRDGAA---GVKGDRGETGAVGAPGAPGPPGSP--GPA--GPTGKQGDRGEA 1022
Query: 514 GSSSVFAESPGGKTRSAGSASTAGAPPSELFPG----PGERSLVGF----------GPPV 559
G A+ P G + AG+ G G PGER L G GPP
Sbjct: 1023 G-----AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1077
Query: 560 PAKDTETRERMEAMEKQIASLTGLVQSALLRGSE-PETPSEKIEGSNGAATPSAPCGSGG 618
P+ D +G + RG P PS K +G+NG P P G G
Sbjct: 1078 PSGDQ--------------GASGPAGPSGPRGPPGPVGPSGK-DGANGIPGPIGPPGPRG 1122
Query: 619 RSSGATPVSGPPPPSASSTPAGQP 642
R SG T +GPP P G P
Sbjct: 1123 R-SGETGPAGPPGNPGPPGPPGPP 1145
Score = 47.0 bits (110), Expect = 1e-04
Identities = 94/387 (24%), Positives = 128/387 (33%), Gaps = 70/387 (18%)
Query: 298 SPAPHLASGSP-PPGLPSGLPSGLQSGSPSRSRLSYAGGR-----------PPSYAGSPV 345
+P P G P PPGL + + G ++ + G PP AG+P
Sbjct: 91 NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150
Query: 346 HHAAERLGGAPAAQGVS--------PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYA 397
+ G P GVS P P KP +D + G GE
Sbjct: 151 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPG-------KPGDDGEAGKPGKA---GERGPP 200
Query: 398 DPYGLL-HEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAG 456
P G G L G YPG G + S + ++ G
Sbjct: 201 GPQGARGFPGTPGLPGVKGHR-GYPGLDGAKGEAGAPGVKGESGSPGEN----------G 249
Query: 457 GGGPLYGDGYGFRLPPSSPQKLA-----DVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRK 511
GP+ G + P A D P GPP P P GP G+P +
Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 309
Query: 512 DSGS-SSVFAESPGGKTRSAGSASTAGA---PPSELFPG-------PGERSLVGF----G 556
+G+ A+ P G+ + GS AGA P ++ PG PG GF G
Sbjct: 310 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369
Query: 557 PPVPAKDT-ETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCG 615
PP P T + + E IA G +G + E +G+ G A G
Sbjct: 370 PPGPQGATGPLGPKGQTGEPGIAGFKG------EQGPKGEPGPAGPQGAPGPAGEEGKRG 423
Query: 616 SGGRSSGATPVSGPPPPSASSTPAGQP 642
+ G G P+ GPP + G P
Sbjct: 424 ARGEPGGVGPI-GPPGERGAPGNRGFP 449
Score = 47.0 bits (110), Expect = 1e-04
Identities = 98/374 (26%), Positives = 121/374 (32%), Gaps = 55/374 (14%)
Query: 299 PAPHLASGSPPPGLPSGLPS--GLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAP 356
P P A+G P GLP GL+ G P + + A G PP AG + G
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLR-GLPGKDGETGAAG-PPGPAGPAGERGEQGAPGPS 593
Query: 357 AAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGD 416
QG+ P P D+ + +AG LV G P G L G
Sbjct: 594 GFQGL-PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 652
Query: 417 PFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDG-YGFRLPPSSP 475
P G G LQ + AAG GP G G + P +P
Sbjct: 653 PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER--GAAGIAGPKGDRGDVGEKGPEGAP 710
Query: 476 QK-----LADVAAPPG--------GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAES 522
K L PPG G P P +RG+P + G + FA
Sbjct: 711 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG-FAGP 769
Query: 523 PG--------GKTRSAGSASTAGAP-PSELFPGPGERSLVGFGPPVPAKDTETRERMEAM 573
PG G+ AG AGAP P PG + G P A+ +
Sbjct: 770 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP----- 824
Query: 574 EKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRS--SGATPVSGPPP 631
TG +A G GSNG P P G G+ GA SGPP
Sbjct: 825 -----GATGFPGAAGRVGPP---------GSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 870
Query: 632 PSAS---STPAGQP 642
+ PAG P
Sbjct: 871 RAGEPGLQGPAGPP 884
Score = 36.6 bits (83), Expect = 0.15
Identities = 60/226 (26%), Positives = 72/226 (31%), Gaps = 50/226 (22%)
Query: 456 GGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGS 515
G GP DG P +P PPG P PP P G K G+
Sbjct: 75 GAPGPRGRDG-----EPGTPGN----PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGA 125
Query: 516 SSVFAESPGGKTRSAGSASTAGAPPSELFPG----PGERSLVG----FGPP----VPAKD 563
+ P G G AGAP + F G PGE + G GPP P D
Sbjct: 126 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDD 185
Query: 564 TETRERMEAME---------KQIASLTGLVQSALLRG--------SEPETPSEKIE---- 602
E + +A E + GL RG E P K E
Sbjct: 186 GEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP 245
Query: 603 GSNGAATPSAPCGSGGR--------SSGATPVSGPPPPSASSTPAG 640
G NG+ P P G G ++GA G P P+ P G
Sbjct: 246 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 291
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 53.1 bits (126), Expect = 2e-06
Identities = 107/451 (23%), Positives = 165/451 (36%), Gaps = 112/451 (24%)
Query: 472 PSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQ-SFRKDSGSSSVFAESPGGKTRSA 530
P PQ+ A V +PP P PP +P P R S +R+ +FR S + + P
Sbjct: 571 PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPP------- 623
Query: 531 GSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLR 590
APP P P PP PA T +R + LLR
Sbjct: 624 -------APPPPPAPSP---------PPAPA--TSSRRPL-----------------LLR 648
Query: 591 GSEPETPSE-KIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPA-GQPTAVSR- 647
+ TPSE ++ TP GA P PP A +PA +P AV R
Sbjct: 649 APQ-FTPSEAHLKIYESVLTPP--------PLGAPEAPEPEPPPADDSPAEPEPRAVGRT 699
Query: 648 ---------------LQMQLHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAE 692
++ ++ G ++ + Q Q L+ LQ + + L + +
Sbjct: 700 NHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQ 759
Query: 693 LSMRVSEAARRQEDPLQRQRTL---------VEEERLRYLNDEELITQQLNDLEKSVEKI 743
L S +Q PL++ R VEE+ L ++ L K ++
Sbjct: 760 LQPPPSP---QQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKV------QLFKIDQQQ 810
Query: 744 QRDVSHNHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVKFLKE 803
Q+ V+ + L PG ++EE A +KQ+ + R +R E E+V+ +E
Sbjct: 811 QQKVAASMPLSPGGQMEEVAGAVKQISD----------------RGPVRSEDESVEAKRE 854
Query: 804 EPQRLDGLLKR------CRGVTDTLAQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFNKS 857
P + ++ CR L Q R V E V P + L ++ A D + +
Sbjct: 855 RPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDV--PRLSALPLRDRQDLATEDTSSA 912
Query: 858 VDFEMPPPSPPLNLHELSGPAEGASLTPKGG 888
+ E P E +GP + T GG
Sbjct: 913 SETESVPSRSRRGKVEAAGPGGESEPTGSGG 943
Score = 33.1 bits (74), Expect = 1.6
Identities = 58/230 (25%), Positives = 78/230 (33%), Gaps = 43/230 (18%)
Query: 460 PLYGDGYGFRLPPSSPQKLA---------DVAAPPG--------GPPPPHSPYSGPPSRG 502
PL G +G P SP L D APP P PP S ++ PP +
Sbjct: 1876 PLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKT 1935
Query: 503 SPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAK 562
SP R +S V A +P ++G + G PS PP P
Sbjct: 1936 SP---QLRVPPPTSVVTALTP-----TSGELAPPGPAPS---------------PPPPED 1972
Query: 563 DTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSG 622
E ME + S L +A L G+EP G+ G ++ P S S
Sbjct: 1973 LGPDFEDMEVVSG--LSAADLDFAASLLGTEPFQEEIVAAGAMG-SSHGGPGDSSEEESS 2029
Query: 623 ATPVSGPPPPSASSTPAGQPTAVSRLQMQLHLRGLQNSASDLRGQLQQLR 672
T P + S P P+A L G+ + +QQ R
Sbjct: 2030 PTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPR 2079
Score = 32.0 bits (71), Expect = 3.6
Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 21/125 (16%)
Query: 863 PPPSPPLNLHELSGPAEGASLTPKGGNPTKGLDTPGKRSVDKAVSVEAAERDWE----EK 918
PPP PPL L SGPA P+ K + T RS +A D + E
Sbjct: 2254 PPPPPPLTLVLSSGPAS----PPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASED 2309
Query: 919 RAALTQYSAKDINRLLEETQAELLKAIPDLD----CASKAHPGP-------APTPDHKPP 967
+ + +R+ +T ++ + DLD A + PGP P P+ PP
Sbjct: 2310 TPQVPGLGSGGFSRVRMKTPT--VRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPP 2367
Query: 968 KAPHG 972
+ P G
Sbjct: 2368 QVPDG 2372
Score = 31.2 bits (69), Expect = 6.1
Identities = 25/71 (35%), Positives = 30/71 (42%), Gaps = 10/71 (14%)
Query: 958 PAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYR-----TEKPSKSPPPPPPRRS 1012
PAP P PP+AP + P P RR L P +R E P P PPPP
Sbjct: 577 PAPVPS--PPRAPT-PPSTPVPLPEKRRSI--LREPTFRWTSLTRELPPPPPAPPPPPAP 631
Query: 1013 FPSSHGLTTTR 1023
P T++R
Sbjct: 632 SPPPAPATSSR 642
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 52.4 bits (124), Expect = 3e-06
Identities = 93/361 (25%), Positives = 112/361 (31%), Gaps = 60/361 (16%)
Query: 306 GSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVSPSP 365
G PPPG P G P G SRS S PP P + G P G P
Sbjct: 91 GPPPPGKPQGPPP---QGDKSRSPRS-----PPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142
Query: 366 SAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPGAGG 425
P + G K +G P G S + G P P GG
Sbjct: 143 ----------PPQGGNKPQGPPPPGKPQG--PPPQG--DNKSRSSRSPPGKPQGPPPQGG 188
Query: 426 LYKRGSVRSLSTYSAAALQSDLEDSLYKAAGG--GGPLYGDG--YGFRLPPSSPQKLADV 481
+G Q + G G P GD R PP PQ
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ 248
Query: 482 AA--PPGGPPPPHSPY----------SGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRS 529
P G PPPP P GPP G P Q GS S + SP GK +
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--QGPPPQGGSKSRSSRSPPGKPQG 306
Query: 530 ---AGSASTAGAPPSELFP--GPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLV 584
G G PP P P + GPP P K + + + S G
Sbjct: 307 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPG-- 364
Query: 585 QSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPV---SGPPPPSASSTPAGQ 641
+P+ P ++ EG+N P P G + A P GPP P P+
Sbjct: 365 --------KPQGPPQQ-EGNNPQG-PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414
Query: 642 P 642
P
Sbjct: 415 P 415
Score = 48.9 bits (115), Expect = 3e-05
Identities = 65/233 (27%), Positives = 78/233 (33%), Gaps = 34/233 (14%)
Query: 431 SVRSLSTYSAAALQSDL--EDSLYKAAGG--GGPLYGDG--YGFRLPPSSPQKLADVAA- 483
SV L+ SA L D+ E+S AG G P G G PP PQ
Sbjct: 7 SVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGN 66
Query: 484 -PPGGPPPPHSPYSGPPSRGS-------PVRQSFRKDSGSSSVFAESPGGKTRS---AGS 532
P G PPPP P PP G+ P + G S SP GK + G
Sbjct: 67 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 126
Query: 533 ASTAGAPPSELFP--GPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLR 590
G PP P P + GPP P K + + + S G
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPG-------- 178
Query: 591 GSEPETPSEKIEGSNGAATPSAPCG--SGGRSSGATPVSGPPPPSASSTPAGQ 641
+P+ P +G N P P G G G GPPPP P Q
Sbjct: 179 --KPQGPPP--QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 227
Score = 48.9 bits (115), Expect = 3e-05
Identities = 93/373 (24%), Positives = 113/373 (30%), Gaps = 49/373 (13%)
Query: 285 SRESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPP--SYAG 342
S+E SP+ N AP G+ P G PS P G G P + G PP G
Sbjct: 24 SQEESPSLIAGNPQGAPP-QGGNKPQGPPS--PPGKPQGPPPQGGNQPQGPPPPPGKPQG 80
Query: 343 SPVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGL 402
P + G P + P P R P K G G P
Sbjct: 81 PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP----GKPQGPPPQGGNQPQGPP--- 133
Query: 403 LHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGG---GG 459
G P P GG +G Q D + ++ G G
Sbjct: 134 ---------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-QGDNKSRSSRSPPGKPQGP 183
Query: 460 PLYGDGY--GFRLPPSSPQKLADVAA-PPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSS 516
P G G PP PQ P GPPPP GPP +G QS R G
Sbjct: 184 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP-GKPQGPPPQGDNKSQSARSPPGKP 242
Query: 517 SVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQ 576
P G + G G P P + GPP P K + + +
Sbjct: 243 Q--GPPPQGGNQPQGPPPPPGKPQGP----PPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296
Query: 577 IASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCG--SGGRSSGATPVSGPPPPSA 634
S G +P+ P +G N P P G G G GPPPP
Sbjct: 297 SRSPPG----------KPQGPPP--QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 344
Query: 635 SSTPAGQPTAVSR 647
P Q + SR
Sbjct: 345 PQGPPPQGGSKSR 357
>gi|150378478 PR domain containing 8 [Homo sapiens]
Length = 689
Score = 52.4 bits (124), Expect = 3e-06
Identities = 101/395 (25%), Positives = 137/395 (34%), Gaps = 81/395 (20%)
Query: 285 SRESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSP 344
+RE +R ++ SPA L+SGS SG G Q S ++ GG+
Sbjct: 265 ARELENSRGGSSCSPAQSLSSGSG-----SGGGGGHQEAELSPDGIATGGGKGKRKFPE- 318
Query: 345 VHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLH 404
AAE GGA G+ +ER EDL + G Y +GL
Sbjct: 319 --EAAEGGGGA----GLVGGRGRFVERPLPASKEDLVCTPQQY---RASGSY---FGLEE 366
Query: 405 EGRL----SLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGP 460
GRL S A+ + S++ T A + S+ +D AGGGG
Sbjct: 367 NGRLFAPPSPETGEAKRSAFVEVKKAARAASLQEEGTADGAGVASEDQD-----AGGGG- 420
Query: 461 LYGDGYGFRLPPS-SPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVF 519
G P + SP + AP G P P G P+RG S F
Sbjct: 421 ------GSSTPAAASPVGAEKLLAPRPGGPLPSRLEGGSPARG--------------SAF 460
Query: 520 AESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIAS 579
P + SAGS S G G G + G G A E + + +
Sbjct: 461 TSVP--QLGSAGSTSGGG--------GTGAGAAGGAGGGQGAASDERKSAFSQPARSFSQ 510
Query: 580 LTGLVQSALLRGSEPETPSEKIEGS--------------NGAATPSAPCGSGGRSSGATP 625
L+ LV L EP P++ + + GAA + CGS G P
Sbjct: 511 LSPLVLGQKLGALEPCHPADGVGPTRLYPAAADPLAVKLQGAADLNGGCGSLPSGGGGLP 570
Query: 626 VSGP--------PPPSASSTPAGQPTAVSRLQMQL 652
P P SA++ A A LQ+QL
Sbjct: 571 KQSPFLYATAFWPKSSAAAAAAAAAAAAGPLQLQL 605
>gi|150378439 PR domain containing 8 [Homo sapiens]
Length = 689
Score = 52.4 bits (124), Expect = 3e-06
Identities = 101/395 (25%), Positives = 137/395 (34%), Gaps = 81/395 (20%)
Query: 285 SRESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSP 344
+RE +R ++ SPA L+SGS SG G Q S ++ GG+
Sbjct: 265 ARELENSRGGSSCSPAQSLSSGSG-----SGGGGGHQEAELSPDGIATGGGKGKRKFPE- 318
Query: 345 VHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLH 404
AAE GGA G+ +ER EDL + G Y +GL
Sbjct: 319 --EAAEGGGGA----GLVGGRGRFVERPLPASKEDLVCTPQQY---RASGSY---FGLEE 366
Query: 405 EGRL----SLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGP 460
GRL S A+ + S++ T A + S+ +D AGGGG
Sbjct: 367 NGRLFAPPSPETGEAKRSAFVEVKKAARAASLQEEGTADGAGVASEDQD-----AGGGG- 420
Query: 461 LYGDGYGFRLPPS-SPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVF 519
G P + SP + AP G P P G P+RG S F
Sbjct: 421 ------GSSTPAAASPVGAEKLLAPRPGGPLPSRLEGGSPARG--------------SAF 460
Query: 520 AESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIAS 579
P + SAGS S G G G + G G A E + + +
Sbjct: 461 TSVP--QLGSAGSTSGGG--------GTGAGAAGGAGGGQGAASDERKSAFSQPARSFSQ 510
Query: 580 LTGLVQSALLRGSEPETPSEKIEGS--------------NGAATPSAPCGSGGRSSGATP 625
L+ LV L EP P++ + + GAA + CGS G P
Sbjct: 511 LSPLVLGQKLGALEPCHPADGVGPTRLYPAAADPLAVKLQGAADLNGGCGSLPSGGGGLP 570
Query: 626 VSGP--------PPPSASSTPAGQPTAVSRLQMQL 652
P P SA++ A A LQ+QL
Sbjct: 571 KQSPFLYATAFWPKSSAAAAAAAAAAAAGPLQLQL 605
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 52.0 bits (123), Expect = 3e-06
Identities = 100/363 (27%), Positives = 128/363 (35%), Gaps = 47/363 (12%)
Query: 298 SPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPA 357
SP P +GSP P P+G+P GL+ G ++ PP G P +A R+G P
Sbjct: 874 SPGPQGLAGSPGPHGPNGVP-GLKGGRGTQG--------PPGATGFP--GSAGRVG--PP 920
Query: 358 AQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDP 417
+P P+ L + L G V G P G +G G P
Sbjct: 921 GPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG-P 979
Query: 418 FAYPG-AGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQ 476
PG AG +RG V + L AG G + G P P
Sbjct: 980 DGPPGPAGTTGQRGIVGMPGQRGERGM-----PGLPGPAGTPGKVGPTGATGDKGPPGP- 1033
Query: 477 KLADVAAPPG-----GPPPPHSP--YSGPPSR-GSPVRQSFRKDSGSSSVFAE--SPG-- 524
PPG G P P P G P R G+ + R D G + + +PG
Sbjct: 1034 -----VGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTP 1088
Query: 525 GKTRSAGSASTAGAPPSELFPGP----GERSLVGFGPPVPAKDT-ETRERMEAMEKQIAS 579
G + G A G P S GP G+R L GP P D + +R + +K
Sbjct: 1089 GPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP--GPQGPRGDKGDHGDRGDRGQKGHRG 1146
Query: 580 LTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVS--GPPPPSASST 637
TGL G E S I G G P P G G+ P+ GPP S
Sbjct: 1147 FTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVG 1206
Query: 638 PAG 640
AG
Sbjct: 1207 EAG 1209
Score = 45.4 bits (106), Expect = 3e-04
Identities = 97/353 (27%), Positives = 114/353 (32%), Gaps = 71/353 (20%)
Query: 299 PAPHLASGSPPPGLPSGLPSGLQS--GSPSRSRLSYAGGRPPSYAGSPVHHAAE-RLG-- 353
P P A G P SG P G Q G P L A G G+P E +LG
Sbjct: 536 PGPKGAQGERGPVGSSG-PKGSQGDPGRPGEPGLPGARG----LTGNPGVQGPEGKLGPL 590
Query: 354 GAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAA 413
GAP G P +I + + G M L +G DP G+ A
Sbjct: 591 GAPGEDGRPGPPGSI----------GIRGQPGSMGLPGPKGSSGDP------GKPGEAGN 634
Query: 414 AGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGY-GFRLPP 472
AG P GA G K G V L + + G GP G G PP
Sbjct: 635 AGVP-GQRGAPG--KDGEVGPSGPVGPPGLAGERGEQ-----GPPGPTGFQGLPGPPGPP 686
Query: 473 SSPQKLADVAAP--PG--GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTR 528
K D P PG GP P P RG P + G + P G
Sbjct: 687 GEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG--GHGPDGPKG 744
Query: 529 SAGSASTAG-APPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSA 587
S G + T G P L PGER + G P P D
Sbjct: 745 SPGPSGTPGDTGPPGLQGMPGERGIAG--TPGPKGD------------------------ 778
Query: 588 LLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAG 640
RG E +E G++GA P G G +G T G P P P G
Sbjct: 779 --RGGIGEKGAEGTAGNDGARGLPGPLGPPG-PAGPTGEKGEPGPRGLVGPPG 828
Score = 36.6 bits (83), Expect = 0.15
Identities = 59/215 (27%), Positives = 70/215 (32%), Gaps = 36/215 (16%)
Query: 456 GGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSP-YSGPPSR----GSPVRQSFR 510
GG GP G P P PPG P P +G P GSP + F
Sbjct: 231 GGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFP 290
Query: 511 KDSGSSSVFA-------ESPGGKTRSAGSASTAG--APPSELFP-----GPGERSLVGFG 556
G + E P G+ + GS AG P + P PGER +G
Sbjct: 291 GAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG-- 348
Query: 557 PPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIE-GSNGAATPSAPCG 615
P A M + L G+ S+ P P K E G GA P P G
Sbjct: 349 -PQGAPGQRGAHGMPGKPGPMGPL-GIPGSS----GFPGNPGMKGEAGPTGARGPEGPQG 402
Query: 616 SGGRSSGATPVSGPPPPSASST--------PAGQP 642
G + PV P P A T P G P
Sbjct: 403 QRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSP 437
Score = 35.0 bits (79), Expect = 0.42
Identities = 87/370 (23%), Positives = 112/370 (30%), Gaps = 47/370 (12%)
Query: 299 PAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPS--YAGSPVHHAAERLGGAP 356
P P GS P P G P + G P R+ G P +AGSP A GAP
Sbjct: 245 PGPMGPIGSRGPEGPPGKPG--EDGEPGRN------GNPGEVGFAGSP---GARGFPGAP 293
Query: 357 AAQGVS--------PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRL 408
G+ P + K + G M + G+ + L +G
Sbjct: 294 GLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAP 353
Query: 409 SLAAAAG--------DPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGP 460
A G P PG+ G ++ + + A + + G GP
Sbjct: 354 GQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGET-GPPGP 412
Query: 461 LYGDGYGFRLPPSSPQKLADVAAPPG--GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSV 518
+ G + PG GPP P P +GS Q R G V
Sbjct: 413 VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGV 472
Query: 519 ----FAESPGGKTRSAGSASTAGAPPSELFPGP-GERSLVGFGPPVPAKDTETRERMEAM 573
P G+ G G P E GP G+ V GPP P ER
Sbjct: 473 PGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV--GPPGP-----VGERGAPG 525
Query: 574 EKQIASLTGLVQSALLRGSEPETPSEKIEGSNG-AATPSAPCGSGGRSSGATPVSGPPPP 632
+ GL +G S +GS G P P G R G T G P
Sbjct: 526 NRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR--GLTGNPGVQGP 583
Query: 633 SASSTPAGQP 642
P G P
Sbjct: 584 EGKLGPLGAP 593
Score = 33.9 bits (76), Expect = 0.94
Identities = 59/221 (26%), Positives = 65/221 (29%), Gaps = 33/221 (14%)
Query: 456 GGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPP----HSPYSGPPSRGSPVRQSFR- 510
G GP G R P PQ + PG P P H + GP P
Sbjct: 138 GSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG 197
Query: 511 --KDSGSSSVFAESPG-----------GKTRSAGSASTAGAPPSELFPGP----GERSLV 553
+ SG S PG G G A G P PGP G R
Sbjct: 198 LDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPE 257
Query: 554 GFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRG--SEPETPSEK-IEGSNGAATP 610
G P P +D E E G S RG P P K G G P
Sbjct: 258 G-PPGKPGEDGEPGRNGNPGE------VGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGP 310
Query: 611 SAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQMQ 651
G+ G A P +GP P G P RL Q
Sbjct: 311 KGEVGAPGSKGEAGP-TGPMGAMGPLGPRGMPGERGRLGPQ 350
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 51.2 bits (121), Expect = 6e-06
Identities = 59/251 (23%), Positives = 110/251 (43%), Gaps = 40/251 (15%)
Query: 567 RERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPV 626
R+RM+ M +Q+ +L + ++ R E ET ++ +
Sbjct: 408 RQRMQQMSEQVHTLREEKECSMSRVQELETSLAELRNQ---------------------M 446
Query: 627 SGPPPPSASSTPAGQPTAVSRLQMQL-HLRG-LQNSASDLRGQLQQLRKLQLQNQESVRA 684
+ PPPP PAG +LQ + HLR L+ A L+ Q+Q L N+E
Sbjct: 447 AEPPPPEP---PAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEER 503
Query: 685 LLK-RTEAELSMRVSEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEKI 743
LL+ AEL +EA R+ + +Q RT + R L+ + +QL +L+ K+
Sbjct: 504 LLELERAAELWGEQAEARRQILETMQNDRTTIS----RALSQNRELKEQLAELQSGFVKL 559
Query: 744 QRDVSHNHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVKFLKE 803
N + L+ + V ++LG+ L EL+ S+++ + ++ + + L++
Sbjct: 560 T-----NENMEITSALQSEQHVKRELGKKLGELQEKL----SELKETVELKSQEAQSLQQ 610
Query: 804 EPQRLDGLLKR 814
+ + G L++
Sbjct: 611 QRDQYLGHLQQ 621
Score = 33.5 bits (75), Expect = 1.2
Identities = 46/228 (20%), Positives = 92/228 (40%), Gaps = 16/228 (7%)
Query: 592 SEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQMQ 651
S E+ + + NG SA C +G + + + A + V+ Q+
Sbjct: 122 SSTESLRQLSQQLNGLVCESATCVNGEGPASSANLKDLESRYQQLAVALDSSYVTNKQLN 181
Query: 652 LHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQ 711
+ + L+ ++ QL++ +K Q Q ++R L+ + + VSE A Q Q
Sbjct: 182 ITIEKLKQQNQEITDQLEEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQ 241
Query: 712 RTLVEEE--------RLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKA 763
++E RL+Y +++ +LE+++ + R E A
Sbjct: 242 HAARQKEGESEDLASRLQYSR------RRVGELERALSAVSTQQKKADRYNKELTKERDA 295
Query: 764 LVLKQLGETLT--ELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLD 809
L L+ T + +LK L+ K+RV++ + L+E ++L+
Sbjct: 296 LRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLE 343
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 50.8 bits (120), Expect = 7e-06
Identities = 88/380 (23%), Positives = 125/380 (32%), Gaps = 56/380 (14%)
Query: 298 SPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPA 357
+PA + S SP + P G+ + + + PPS G P + + PA
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967
Query: 358 AQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDP 417
A SP P A+ KG P G ++ + G P
Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPAATPPS----PKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 418 FAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAA----------GGGGPLYGDGYG 467
A P + +G+ + + S L K A GGP G
Sbjct: 1024 AATP-----FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Query: 468 FRLPPS----SPQKLADVAAPPGGPPP----PHSPYSG---PPSRGSPVRQSFRKDSGSS 516
PP+ SP+ +P G P P P SP G PP +G+P + S
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 517 SVFAESPGGKTRSAGSASTAGAPPSELF--PGPGERSLVGFGPPVPAKDTETRERMEAME 574
+ P G + A+T +P L P G + PP P T
Sbjct: 1139 GLATPPPKGAPTT--PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT-------- 1188
Query: 575 KQIASLTGLVQSALLRGSEPE----TPSEKIEGSNGAATPSAPCGS----GGRSSGATPV 626
S G + P+ TPS K + AATP +P G + + TP
Sbjct: 1189 ---PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245
Query: 627 SGPPPPS---ASSTPAGQPT 643
+ PP P A+ P G PT
Sbjct: 1246 ATPPSPKGGPATPPPKGAPT 1265
Score = 46.2 bits (108), Expect = 2e-04
Identities = 91/402 (22%), Positives = 128/402 (31%), Gaps = 51/402 (12%)
Query: 288 SSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHH 347
++P L+ PH + + P P GL + P + + A PPS G
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA-TPPSPKGGLATP 1166
Query: 348 AAERLGGAPAAQGVSPSPSAILERRDVK-----PDEDLASKAGGMVLVKGEGLYADPYGL 402
+ PAA PSP L K P S GG+ +G P
Sbjct: 1167 PPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224
Query: 403 --LHEGRLSLAAAAGDPFAYPGAGGLYKRGSV----RSLSTYSAA---ALQSDLEDSLYK 453
+G L+ + G P K G + T AA +L+ L +K
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 454 AAGG----------GGPLYGDGYGFRLPPS----SPQKLADVAAPPGGPPPPHS------ 493
A GGP G PP+ SP+ P G P PP
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
Query: 494 -----PYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPG 548
P + P S+G P S ++ + GG + S A PS P
Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK-GDPT 1403
Query: 549 ERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRG-------SEPETPSEKI 601
+++ P TRE K + + +L + P TPS K
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
Query: 602 EGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPT 643
+ + A TP +P AT S P A+ P G PT
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATS-SSPKKAPATPAPMGAPT 1504
Score = 44.7 bits (104), Expect = 5e-04
Identities = 89/385 (23%), Positives = 122/385 (31%), Gaps = 39/385 (10%)
Query: 294 LNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLG 353
L L AP + P P LP P+G G+ +S+ P A SP E G
Sbjct: 721 LATLVLAPEIPKSVPSPSLP---PAGTPPGTKKVDGISHTSALAP-VASSPKECPTEDSG 776
Query: 354 GAPAAQGV--------SPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPY--GLL 403
+ A SPSP + K AG + P L
Sbjct: 777 ASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL 836
Query: 404 HEGRLSLAAAAGDPFAY-----PGAGGLYKRGSVRSLSTYSAAALQSD-----LEDSLYK 453
E LS + P P G +V LS + + + +
Sbjct: 837 PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896
Query: 454 AAGGGGPLYGDGYGFRLPPSSPQKLADVAAP---PGGPPP---PHSPYSGPPS-RGSPVR 506
G P + SSP+K AP P P P P P + PPS +G P
Sbjct: 897 KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
Query: 507 QSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGP--GERSLVGFGPPVPAKDT 564
S + + SP G + S A PP+ P P G + G P P T
Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATP-SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
Query: 565 ETRERMEAMEKQI---ASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSS 621
+ AS +GS TP K + AAT +P GG ++
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP--KGGPAT 1073
Query: 622 GATPVSGPPPPSASSTPAGQPTAVS 646
+ + PP + +P G P S
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPS 1098
Score = 43.9 bits (102), Expect = 0.001
Identities = 91/409 (22%), Positives = 133/409 (32%), Gaps = 76/409 (18%)
Query: 288 SSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHH 347
++P L+ PH + +P P P G + SP + + PPS GSP
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPS-PKGGPATSPPKGAPTPPAATPPSPKGSP--- 1324
Query: 348 AAERLGGAPAAQGVSPSPSAIL----ERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLL 403
G P +G +P+P A+ + P +SK G EG
Sbjct: 1325 ------GTPPPKG-APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377
Query: 404 HEGRLSLAAAAGDPF-AYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLY 462
H+G ++ + A P G +V LS A A E G P
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE-------GAATPSK 1430
Query: 463 GDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAES 522
GD + P S +K +AP GGP P S G P+ + S ++ V S
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSS--KGDPTLPAVTPPSPKEPPAPKQVATSS 1488
Query: 523 PGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLT- 581
K + + A P+ + P E VPA + R+ + ++ T
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKE---------VPATPSSRRDPIAPTATLLSKKTP 1539
Query: 582 -------GLVQSALLRGSE------------PETPSEKIEGSNGAATPSAPCGSGGRS-- 620
L+ A+ S P TPS K S A TPS G+
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599
Query: 621 --------------------SGATPVSGPPPPSASSTPAGQPTAVSRLQ 649
+ +P GP P+ TP P S L+
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK 1648
Score = 40.0 bits (92), Expect = 0.013
Identities = 53/202 (26%), Positives = 65/202 (32%), Gaps = 27/202 (13%)
Query: 835 PPPNNLLSQSPKKVTAETDFNK--SVDFEMPPPSPPLNLHELSGPAEGASLTPKGGNPTK 892
P P + SPK A T F K S PPSP PA A+ PKG T
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK------GSPA--ATPLPKGAPTTP 1060
Query: 893 GLDTPGKRSVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAI----PDL 948
P + S++ A A T S K A + A P
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTP-----PAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 949 DCASKAHPGPAPTPDHKPPKA--------PHGQKAAPRTEPSGRRGSDELTVPRYRTEKP 1000
A+ H G TP PP P G P P +G P+ P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 1001 SKSPPPPPPRRSFPSSHGLTTT 1022
+ +PP P + PS G TT
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTT 1197
Score = 39.7 bits (91), Expect = 0.017
Identities = 91/374 (24%), Positives = 132/374 (35%), Gaps = 57/374 (15%)
Query: 281 MVYASRESSPTRRLNN------LSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAG 334
+V A+ ++SP+ + + LSP LA S LP G P+ + SP S +
Sbjct: 562 LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMT-SPLGVNSSASV 620
Query: 335 GRPPSYAGSPVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEG 394
+ SYAG + G + ++P+ +A P E KG
Sbjct: 621 IKTDSYAGP------DSAGPLLKSSLITPTVAAF-------PLESADPAGVAPTTAKGTS 667
Query: 395 LYADPYGLLHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKA 454
Y EG +SLA P +P K G++ +L A+ + S
Sbjct: 668 TYTTTASPFLEGTVSLA-----PKNHP-----VKEGTLTTLPLVPTASENCPVAPSPQNT 717
Query: 455 AGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSG-------PPSRGSPVRQ 507
L L P P+ + + PP G PP G P SP ++
Sbjct: 718 CAPLATLV-------LAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSP-KE 769
Query: 508 SFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETR 567
+DSG+S+ A S G T A S S G S P + GP P + +
Sbjct: 770 CPTEDSGASAT-ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKK-GSAGPDTPIGNLSSP 827
Query: 568 -ERMEA--MEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGAT 624
+EA + + S G S S P PS K + A TP +P G
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHS-PTPPSPKGAPTPSAVTPLSPKGV------TL 880
Query: 625 PVSGPPPPSASSTP 638
P P PS + P
Sbjct: 881 PPKETPTPSVVNLP 894
Score = 38.1 bits (87), Expect = 0.050
Identities = 81/369 (21%), Positives = 116/369 (31%), Gaps = 48/369 (13%)
Query: 301 PHLASGSPPPGLPSGLPSGLQSGSPSRSRLSY----AGGRPPSYAGSPVHHAAERLGGAP 356
P A+ P G P+ P L G+P+ + G PS G+P AA +P
Sbjct: 1035 PPAATPPSPKGSPAATP--LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP--PSP 1090
Query: 357 AAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGL--LHEGRLSLAAAA 414
+PSP + P S GG+ +G P +G L+
Sbjct: 1091 KGGPATPSPKGA----PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
Query: 415 GDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPS- 473
G P P A +G + + A + S P PPS
Sbjct: 1147 GAPTT-PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205
Query: 474 -----SPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTR 528
+P P PP P + P +G+P + S P G
Sbjct: 1206 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
Query: 529 SAGSASTA-----GAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGL 583
+ + PP + P P + PP P T A A+
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVT-----PPSPKGGPATSPPKGAPTPPAATPPSP 1320
Query: 584 VQSALLRGSEPETPSEKIEGSNGAATPSAPCGS--------GGRSSGATPVS--GPPPPS 633
+GS P TP K + A TP +P G+ + TP S GP PP+
Sbjct: 1321 ------KGS-PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 634 ASSTPAGQP 642
A+ + G P
Sbjct: 1374 ATPSHKGGP 1382
Score = 37.7 bits (86), Expect = 0.065
Identities = 78/322 (24%), Positives = 99/322 (30%), Gaps = 49/322 (15%)
Query: 831 EGVWPPPNNLLSQSPKKVTAETDFNKSVDFEMPPPSPPLNLHELSGPAEGASLTPKGGN- 889
E + P N+L Q K A T PPSP P+ L+PKG
Sbjct: 832 EASFLPENSLSFQGSKDSPATTH-------SPTPPSPK----GAPTPSAVTPLSPKGVTL 880
Query: 890 PTKGLDTPGKRSVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLD 949
P K TP ++ A + ++T S K T A K IP
Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA----TPAP--KGIP--- 931
Query: 950 CASKAHPGP--APTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPP 1007
A P P APTP P +P G A P P++ P+ +PP P
Sbjct: 932 ----ASPSPKGAPTPPAATPPSPKGGPATPS--------------PKWAPTPPAATPPSP 973
Query: 1008 PPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPAS 1067
+ PS G T + K V P K A + + AS
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 1068 TPPIMASAIKDEDDEDRIIAELESGGGSVP----PMKVVTPGASRLKAA-QGQAGSPDKS 1122
TPP +A L G + P P P LK A A +P
Sbjct: 1034 TPP---AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090
Query: 1123 KHGKQRAEYMRIQAQQQATKPS 1144
K G AT PS
Sbjct: 1091 KGGPATPSPKGAPMPPAATPPS 1112
Score = 35.0 bits (79), Expect = 0.42
Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 9/76 (11%)
Query: 956 PGPAPTPDHKPPKAPHGQKAAPRTEPSGRRG-----SDELTVPRYRTEK----PSKSPPP 1006
P APTP P +P G P T PS + G S E P T P+ +PP
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388
Query: 1007 PPPRRSFPSSHGLTTT 1022
P + PS G T+
Sbjct: 1389 PKRGPAIPSPKGDPTS 1404
Score = 33.5 bits (75), Expect = 1.2
Identities = 48/225 (21%), Positives = 76/225 (33%), Gaps = 15/225 (6%)
Query: 956 PGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPS 1015
P P P PPK G P P +GS P+ P+ +PP P + P+
Sbjct: 1295 PSPKGGPATSPPK---GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351
Query: 1016 SHGLTTTRTGEVVVTSKKDSAFIKKAESEEL---EVQKPQVKLRRAVSEVARPASTPPIM 1072
+ T + G S K+ A + P K A+ ++P ++
Sbjct: 1352 T---TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 1073 ASAIK--DEDDEDRIIAELESGGGSVPPMKVVTP-GASRLKAAQGQAGSP-DKSKHGKQR 1128
+ K R A S G PP VTP + A G P S G
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPP--AVTPVSLKKAPATSAPKGGPATPSSKGDPT 1466
Query: 1129 AEYMRIQAQQQATKPSKEMSGSNETSSPVSEKPSASRTSIPVLTS 1173
+ + ++ P + + S+ +P + P + T V+ S
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511
Score = 31.2 bits (69), Expect = 6.1
Identities = 69/308 (22%), Positives = 93/308 (30%), Gaps = 43/308 (13%)
Query: 835 PPPNNLLSQSPKKVTAETDFNKSVDFEMPPPSPPLNLHELSGPAEGASLTPKGGNPTK-- 892
P P L+ P K T PPSP L + P +GA TP P+
Sbjct: 1111 PSPKGGLATPPHKGAPTTP-------AATPPSPKGGL--ATPPPKGAPTTPAATPPSPKG 1161
Query: 893 GLDTPGKRSVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCAS 952
GL TP + A + AA + L S K T P A+
Sbjct: 1162 GLATPPPKG---APTTPAATPP--SPKGGLATPSPKGA-----PTTPAATPPSPKGGLAT 1211
Query: 953 KAHPGPAPTPDHKPPK--------APHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSP 1004
+ G TP PP +P G P P +G P+ P+ +P
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271
Query: 1005 P------PPPPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRA 1058
P PP + P+ +T TS A A + P
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG------ 1325
Query: 1059 VSEVARPASTPPIMASAIKDEDDEDRIIAELESGGGSVPPMKV-VTPGASRLKAAQGQAG 1117
+ + A TPP + GG + P K TP A+ G A
Sbjct: 1326 -TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384
Query: 1118 SPDKSKHG 1125
+P K G
Sbjct: 1385 TPPSPKRG 1392
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 50.8 bits (120), Expect = 7e-06
Identities = 87/346 (25%), Positives = 119/346 (34%), Gaps = 87/346 (25%)
Query: 306 GSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVSPSP 365
G P PG P+ GL + SPS LSY+ G P+ +G LGG G SP
Sbjct: 511 GEPYPG-PAAHSQGLPTASPS---LSYSTGHSPALSGHGGGWGPSSLGG-----GGEASP 561
Query: 366 SAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPGAGG 425
S I+ P + G+ G Y LS A+ A PGAG
Sbjct: 562 SHIIRPLQSPP---ATGRPPGVGSPGAPGKY-----------LSSVLASAPFLAPPGAGS 607
Query: 426 LYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLADVAAPP 485
Y A GG GDG +++ A P
Sbjct: 608 --------------------------YAAGAGGYKGKGDG-------------SELLAGP 628
Query: 486 GGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGK-TRSAGSASTAGAPPSELF 544
GGPP + + S + SG+ + E ++ G + AG PP
Sbjct: 629 GGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGT-- 686
Query: 545 PGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRG-----SEPETPSE 599
P AK+ R ++++ + ASL +AL G + + P
Sbjct: 687 ------------PYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPER 734
Query: 600 KIEGSNGAATPSAPCGSGGRSSGATPVSG--PPPPSASSTPAGQPT 643
E G AT G+G + GA PPPP+A ST QPT
Sbjct: 735 GGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQST---QPT 777
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/166 (30%), Positives = 64/166 (38%), Gaps = 29/166 (17%)
Query: 863 PPPSPPLNLHELSGPAEGASLTPKGGNPTKGLDTPGKRSVDKAVSVEAAERDWEEKRAAL 922
PPPS L AE L +P K LD KR+++ S + E D K
Sbjct: 1335 PPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAK---- 1390
Query: 923 TQYSAKDINRLLEETQAELLKAIPDLDCASKAHPGPAPTPDHKPPKAPHGQKAAPRTEP- 981
NR L+E+ + AI LD A P TPD PP AP P P
Sbjct: 1391 --------NRDLQES---ISSAISALDDPPLAGPKDTSTPDG-PPLAPAAAVPGPPPLPG 1438
Query: 982 ---SGRRGSDEL---------TVPRYRTEKPSKSPPPPPPRRSFPS 1015
+ G+ E T P T +P PPPPPP+ + PS
Sbjct: 1439 LPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPS 1484
Score = 46.6 bits (109), Expect = 1e-04
Identities = 94/416 (22%), Positives = 129/416 (31%), Gaps = 76/416 (18%)
Query: 278 RREMVY-ASRESSPTRRL--NNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAG 334
+ +VY +SR S P + APH P+GL +G L +AG
Sbjct: 27 KASLVYGSSRTSHPETDILHRQAYAAPHPLQSYATNHHPAGLSGLFDTG------LHHAG 80
Query: 335 GRPPSYAGSPVHHAAERLGGAPAAQGVS-----PSPSAILERRDVKPDEDLASKA--GGM 387
P + + A E G P S SPS P E S A G
Sbjct: 81 SAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSS 140
Query: 388 VLVKGEGLYADPYGLLHEGR---LSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQ 444
L A + R + + + DP P A GL V L A +
Sbjct: 141 TFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVP 200
Query: 445 SDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSP 504
S L ++ GGG L P L PP P PP P PP R P
Sbjct: 201 SSLG---FERLAGGGVL------------GPAGLGPAQTPPYRPGPPDPP---PPPRHLP 242
Query: 505 VRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGE-----RSLVGFGPPV 559
+ + S +++ AE + + A+ PP P + PP
Sbjct: 243 TQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPP 302
Query: 560 PAKDTETRERMEAMEKQIASLTGLVQSAL--LRGSEPET---------PSEKIEGSNGAA 608
P + + S+ A L G EP PS G++G A
Sbjct: 303 PPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRA 362
Query: 609 T-----------------------PSAPCGSGGRSSGATPVSGPPPPSASSTPAGQ 641
T P G GG + A + PPPP +++TP Q
Sbjct: 363 TGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQ 418
Score = 41.6 bits (96), Expect = 0.005
Identities = 85/312 (27%), Positives = 100/312 (32%), Gaps = 57/312 (18%)
Query: 290 PTRRLNNLSPAPH---LASGSP------PPGLPSGLPSGLQ---SGSPSRSRLSYAGGRP 337
P + P PH L +G P PP P LPS L S SPS S++ P
Sbjct: 767 PPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEP 826
Query: 338 PSYAGSPVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYA 397
+ G+P P P P L+ L A L E L
Sbjct: 827 ATRDGAP----------QPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESL-- 874
Query: 398 DPYGLLHE--GRLS-LAAAAGDP-FAYPGAGGLYKRGSVRSLSTYSAAA----------- 442
DP G + E G L L A GD P + G G+ RS S A
Sbjct: 875 DPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICF 934
Query: 443 ---LQSDLEDSLYKAA----GGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPP--PPHS 493
L D E S + GGG D YG PP A PP GPP P+
Sbjct: 935 PDSLLQDEERSFFPTMEEMFGGGA---ADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYG 991
Query: 494 PY-SGPPSRGSPVRQSFRKDSGS-----SSVFAESPGGKTRSAGSASTAGAPPSELFPGP 547
PY G S P D S+V AE G A+ PP P P
Sbjct: 992 PYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAP 1051
Query: 548 GERSLVGFGPPV 559
G P+
Sbjct: 1052 ASEPKGGLTSPI 1063
Score = 37.7 bits (86), Expect = 0.065
Identities = 53/215 (24%), Positives = 70/215 (32%), Gaps = 44/215 (20%)
Query: 454 AAGGGGPLYGDG----------YGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGS 503
A G GG Y G YG Q L+ + GGPP P SGPP G
Sbjct: 435 AGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP---QPPSGPPPPGL 491
Query: 504 PVRQSFRKDSGSSSVF-----------AESPGGKTRSAGSASTAGAPPSELFPGPGERSL 552
QS+ D ++ A S G T S + + G P+ G G
Sbjct: 492 ATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA--LSGHGG--- 546
Query: 553 VGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSA 612
G+GP E Q TG P P + + +A A
Sbjct: 547 -GWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGV----GSPGAPGKYLSSVLASAPFLA 601
Query: 613 PCGSG----------GRSSGATPVSGPPPPSASST 637
P G+G G+ G+ ++GP P A T
Sbjct: 602 PPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERT 636
Score = 36.2 bits (82), Expect = 0.19
Identities = 24/69 (34%), Positives = 25/69 (36%), Gaps = 11/69 (15%)
Query: 958 PAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFP--- 1014
P P P P H AP PS + L P R P PPPPPP P
Sbjct: 795 PPPPPQLLPSVLSH----APSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQL 850
Query: 1015 ----SSHGL 1019
SHGL
Sbjct: 851 EAHLRSHGL 859
Score = 32.0 bits (71), Expect = 3.6
Identities = 27/97 (27%), Positives = 32/97 (32%), Gaps = 1/97 (1%)
Query: 471 PPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSA 530
PP+ P PP PPPP PP +P S P
Sbjct: 1458 PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPP 1517
Query: 531 GSASTAGAPPSE-LFPGPGERSLVGFGPPVPAKDTET 566
+A+ APP E P P + L P AK ET
Sbjct: 1518 PAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQET 1554
Score = 31.6 bits (70), Expect = 4.7
Identities = 37/160 (23%), Positives = 59/160 (36%), Gaps = 31/160 (19%)
Query: 946 PDLDCASKAHPGPAPTPDHKPPKAPH----GQKAAPRTEPSGRRGSDELTVPR------- 994
P+ + KA GP P P P P+ A P T G + +P
Sbjct: 968 PEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPL 1027
Query: 995 -------YRTEKPSKSPPPPPPRRSFPSSHGLT-----TTRTGEVVVTS------KKDSA 1036
++ P PPPPPP + GLT +T+ +++ TS ++D
Sbjct: 1028 GLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPP 1087
Query: 1037 F--IKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMAS 1074
F KK ++E E + + K P P +++S
Sbjct: 1088 FQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSS 1127
Score = 31.2 bits (69), Expect = 6.1
Identities = 64/264 (24%), Positives = 94/264 (35%), Gaps = 59/264 (22%)
Query: 865 PSPPLNLHELSGPAEGASLTPKGGNPTKGLDTPGKRSVDKAVSVEAAERDWEEKRAALTQ 924
P PL + +LS P G L G+ G D S +EA ++ EEK+
Sbjct: 1221 PLKPLKI-KLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQ----- 1274
Query: 925 YSAKDINRLLEETQAELLKAIPDLDCASKAHPGPAPTPDHKPPKAPHGQKAAPRTEPSGR 984
E ++ + + D + K HP P PP +P K+ P + P+
Sbjct: 1275 ----------PEMKSGFMASFLDFLKSGKRHP-PLYQAGLTPPLSP--PKSVPPSVPA-- 1319
Query: 985 RGSDELTVPRYRTEKPSKSP--PPPPPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAE 1042
R +P +P P PPP +F GL ++ AE
Sbjct: 1320 ---------RGLQPQPPATPAVPHPPPSGAF----GL---------------GGALEAAE 1351
Query: 1043 SEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKDEDDEDRIIAELESGGGSV---PPM 1099
SE L + P +R E+ R T P +S +D ++R + E S S PP+
Sbjct: 1352 SEGLGLGCPS-PCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPL 1410
Query: 1100 ----KVVTPGASRLKAAQGQAGSP 1119
TP L A G P
Sbjct: 1411 AGPKDTSTPDGPPLAPAAAVPGPP 1434
Score = 30.8 bits (68), Expect = 8.0
Identities = 48/209 (22%), Positives = 66/209 (31%), Gaps = 66/209 (31%)
Query: 471 PPSSPQKLADVAAP----PG----GPP-----PPHSPYSGPPSRGSPVRQ---------- 507
PP + Q+L P PG GPP P Y P +G+ +
Sbjct: 876 PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFP 935
Query: 508 -SFRKDSGSS------SVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVP 560
S +D S +F AG G P + P PG + +GP P
Sbjct: 936 DSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCP 995
Query: 561 AKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSA----PCG- 615
+ + G+ PETP ++ + PS P G
Sbjct: 996 GRAS--------------------------GAGPETPGLGLDPNKPPELPSTVNAEPLGL 1029
Query: 616 --SGGRSSGATPVSGPPPPSASSTPAGQP 642
SG + P PPPP A PA +P
Sbjct: 1030 IQSGPHQAAPPPPPPPPPPPA---PASEP 1055
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 50.1 bits (118), Expect = 1e-05
Identities = 60/246 (24%), Positives = 101/246 (41%), Gaps = 16/246 (6%)
Query: 515 SSSVFAE-SPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTET-----RE 568
S+S +E SP K R + S ST+ P+ P PG + PP P T + R
Sbjct: 452 SASTASELSPKSKARPS-SPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRR 510
Query: 569 RMEAMEKQIASLTGLVQSALLRGSE------PETPSEKIEGSNGAATPSAPCGSGGRSSG 622
+ EA E A+ + R S P +P+ S A P +
Sbjct: 511 KEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTD 570
Query: 623 ATPVSGPPPPSASSTPAGQPTA--VSRLQMQLHLRGLQNSASDLRGQLQQLRKLQLQNQE 680
A ++ PP P+ TP+ +P A R + L + A + R + +Q R+LQ + +
Sbjct: 571 AAVLTSPPAPAPPVTPS-KPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDK 629
Query: 681 SVRALLKRTEAELSMRVSEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSV 740
+R EAE ARR+E+ R++ E+E L ++ + + E
Sbjct: 630 RMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAER 689
Query: 741 EKIQRD 746
++++R+
Sbjct: 690 QRLERE 695
Score = 41.2 bits (95), Expect = 0.006
Identities = 63/230 (27%), Positives = 91/230 (39%), Gaps = 39/230 (16%)
Query: 536 AGAPPSELFPGPGERSLVGFG---PPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGS 592
AGAPP+ + P E G PP P + + + T Q L
Sbjct: 11 AGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPL---- 66
Query: 593 EPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPP----PPSASSTPAGQPTAVSRL 648
EPE+PS ++ G A S +S G TP + P PP SS P+ PTAV
Sbjct: 67 EPESPSGQV-GPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPS--PTAVP-- 121
Query: 649 QMQLHLRGLQNSASDLRGQLQQLRK------LQLQNQESVRALLKRTEAELSMRVSEAAR 702
ASD Q+++K L + +E L +A + +A
Sbjct: 122 ------------ASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKA 169
Query: 703 RQEDPLQRQRTLVEEERLRYLNDEELITQ-QLNDLEKSVEK----IQRDV 747
+E LQ +R +EE+RL+ + + Q LEK+ E+ IQR V
Sbjct: 170 LREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSV 219
Score = 37.7 bits (86), Expect = 0.065
Identities = 64/310 (20%), Positives = 111/310 (35%), Gaps = 49/310 (15%)
Query: 841 LSQSPK-KVTAETDFNKSVDFEMPPPSPPLNLHELSGPAE----GASLTPKGGNPTKGLD 895
L SP+ +++A T S + P SP + H + P G +L PK +P
Sbjct: 443 LPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTA 502
Query: 896 TPGKRSVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAH 955
+P R V E E AA + ++ R E + S A
Sbjct: 503 SPKGR-------VRRKEEAKESPSAAGPEDKSQSKRRASNEKE-------------SAAP 542
Query: 956 PGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPS 1015
PAP+P P AP ++ P P T T P+ +PP P + +
Sbjct: 543 ASPAPSPAPSPTPAPPQKEQPPAETP---------TDAAVLTSPPAPAPPVTPSKPMAGT 593
Query: 1016 SHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASA 1075
+ TR ++ ++ + ++ E +E +Q + K R + A A
Sbjct: 594 TDREEATR---LLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEA 650
Query: 1076 IKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQ 1135
+ E+ E R A+ E RL+ + +A + + + +QR E +
Sbjct: 651 RRREEQEAREKAQAEQ------------EEQERLQKQKEEAEARSREEAERQRLEREKHF 698
Query: 1136 AQQQATKPSK 1145
QQ+ + +
Sbjct: 699 QQQEQERQER 708
Score = 32.0 bits (71), Expect = 3.6
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 6/78 (7%)
Query: 944 AIPDLDCASKAHPGPAPTPDHKPPKAPHG---QKAAPRTEPSGRRGSDELTVPRYRTEKP 1000
A P + + P P+P D PP P P T P+ + + +P E P
Sbjct: 13 APPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLP-LEPESP 71
Query: 1001 S--KSPPPPPPRRSFPSS 1016
S P P PP+ PSS
Sbjct: 72 SGQVGPRPAPPQEESPSS 89
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 49.3 bits (116), Expect = 2e-05
Identities = 81/319 (25%), Positives = 134/319 (42%), Gaps = 63/319 (19%)
Query: 561 AKDTETRERMEAMEKQIAS--LTGLVQSALLRGSE--PETPSEKIEGSNGAATPSAPCGS 616
A +TE E ++ + +A L+ L GSE + + + G +G TPS P S
Sbjct: 440 ALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRS 499
Query: 617 G-GRSSGATPVSGPPPP-SASSTPAGQPTAVSRLQMQLH-LRGLQNSASDLRG------- 666
GR G +P GP P S SST A +A+ + Q+Q+ +RG ++ DL G
Sbjct: 500 SPGR--GRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLS 557
Query: 667 -----------QLQQLR-------------KLQLQNQESVRALLKRTEAELSMRVSEAAR 702
QLQ+LR + ++Q S LL R ++ L+ + A +
Sbjct: 558 DSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQ 617
Query: 703 RQED-------------PLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSH 749
+ E+ L+RQR +EEE+ + D + ++L + +E+++
Sbjct: 618 QAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE----- 672
Query: 750 NHRLVPGPELEEKALVLKQL---GETLTELKAHFPGLQSKMRVVLRVEVE-AVKFLKEEP 805
R V EL E L + + L KA +K RVE+E ++ L+ E
Sbjct: 673 GKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAG-RVELELSMTKLRAEE 731
Query: 806 QRLDGLLKRCRGVTDTLAQ 824
L L + + ++LAQ
Sbjct: 732 ASLQDSLSKLSALNESLAQ 750
Score = 43.9 bits (102), Expect = 0.001
Identities = 77/314 (24%), Positives = 128/314 (40%), Gaps = 65/314 (20%)
Query: 572 AMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGA---TPVSG 628
A E Q+ L ++ L G P + GS P+ G G S +P S
Sbjct: 1428 AAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQ 1487
Query: 629 PPPPSASSTPAG---QPTAVSRLQMQL--HLRGLQNSASDLRGQL--------------- 668
PP P +++PA P AV + LR Q +LR Q
Sbjct: 1488 PPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERD 1547
Query: 669 ------QQLRKLQLQNQESVRAL---LKRTEAELSMRVSEAARRQEDPLQRQRTLVEE-- 717
+QL+K +++E+ R++ L +AEL+++ E+ RR E +R+ TL +
Sbjct: 1548 SATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQ-EESVRRSE--RERRATLDQVAT 1604
Query: 718 -ERLRYLNDEELITQQ--LNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQL---GE 771
ER + EL Q ++ ++ + K++ D ++ E L L++ GE
Sbjct: 1605 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Query: 772 T------LTELKAHFPGLQSKM----RVVLRVEVEAVKFLKEEPQRLDGLL--------- 812
L++ +A LQ ++ R V EV+A L+ +RL+G L
Sbjct: 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKA-GTLQLTVERLNGALAKVEESEGA 1723
Query: 813 --KRCRGVTDTLAQ 824
+ RG+T+ LAQ
Sbjct: 1724 LRDKVRGLTEALAQ 1737
Score = 38.9 bits (89), Expect = 0.029
Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 38/200 (19%)
Query: 663 DLRGQLQQLRKLQLQNQE------------------------SVRALLKRTEAELSMRVS 698
+ GQLQQLR++ Q QE S++ L + EAE
Sbjct: 1807 EAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVER 1866
Query: 699 EAARRQEDPLQRQRTL--VEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPG 756
A R ++D + +RTL VE E+LR D ++ + L++++ + +++ R +
Sbjct: 1867 SALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQI-- 1924
Query: 757 PELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRL-----DGL 811
+LE + +VL+Q + A + ++ L+ EVE ++ + + +R
Sbjct: 1925 QQLEAQVVVLEQ-----SHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAH 1979
Query: 812 LKRCRGVTDTLAQIRRQVDE 831
+R RG+ + ++ ++ Q+ +
Sbjct: 1980 RQRVRGLEEQVSTLKGQLQQ 1999
Score = 31.2 bits (69), Expect = 6.1
Identities = 13/37 (35%), Positives = 24/37 (64%)
Query: 561 AKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETP 597
A++ R+R+ +E+Q+++L G +Q L R S P +P
Sbjct: 1974 ARERAHRQRVRGLEEQVSTLKGQLQQELRRSSAPFSP 2010
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 48.9 bits (115), Expect = 3e-05
Identities = 84/340 (24%), Positives = 109/340 (32%), Gaps = 55/340 (16%)
Query: 313 PSGLPSGLQSGSPSRSRLSYAG-GRPPSYAGSPVHHAAERLG----GAPAAQGVS--PSP 365
P+ PS + G P+ Y G G P G A G G P +G + P P
Sbjct: 423 PTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP 482
Query: 366 SAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPGAGG 425
+ D G L +GL P +L PF + G G
Sbjct: 483 PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLML-----------PFRFGGGGD 531
Query: 426 LYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLADVAAPP 485
+G + S A A+ L+ + G GP+ G R P P + P
Sbjct: 532 AGSKGPMVSAQESQAQAI---LQQARLALRGPAGPM---GLTGRPGPVGPPGSGGLKGEP 585
Query: 486 G--GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAES-PGGKTRSAGSASTAGAPPSE 542
G GP P P G P R+ G+ + ++ P G G A G
Sbjct: 586 GDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHR 645
Query: 543 LFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIE 602
PGP GPP P D ER + E L G EP
Sbjct: 646 GDPGPS-------GPPGPPGDDG--ERGDDGEVGPRGLPG----------EP-------- 678
Query: 603 GSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQP 642
G G P P G G G T + G P P + P G+P
Sbjct: 679 GPRGLLGPKGPPGPPG-PPGVTGMDGQPGPKGNVGPQGEP 717
Score = 42.4 bits (98), Expect = 0.003
Identities = 51/169 (30%), Positives = 63/169 (37%), Gaps = 23/169 (13%)
Query: 485 PGGPPPPHSPYS--GPPSRGSPV-RQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAP-P 540
P G P P P GPP P RQ + G + + E P GKT G G P P
Sbjct: 1379 PTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGL--EGPPGKTGPIGPQGAPGKPGP 1436
Query: 541 SEL--FPGP-GERSLVGF----GPPVPAKDTETR----ERMEAMEKQIASLTGLVQSALL 589
L PGP GE+ L G GPP P + EK L GL+
Sbjct: 1437 DGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPP-- 1494
Query: 590 RGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTP 638
G + E + G G+ S P G G + + P+ P PP P
Sbjct: 1495 -GEQGEKGDRGLPGPQGS---SGPKGEQGITGPSGPIGPPGPPGLPGPP 1539
Score = 40.8 bits (94), Expect = 0.008
Identities = 93/376 (24%), Positives = 110/376 (29%), Gaps = 59/376 (15%)
Query: 305 SGSP-PPGL--PSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGV 361
+G P PPG+ P G P+G R G PP G P E G P G+
Sbjct: 990 TGPPGPPGVVGPQG-PTGETGPMGERGHPGPPG--PPGEQGLPGLAGKEGTKGDPGPAGL 1046
Query: 362 SPSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYP 421
P R D L G + L EG P G A AAG P P
Sbjct: 1047 -PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAG-PIGIP 1104
Query: 422 GAGGLY-------KRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSS 474
G G ++G+ A D L G GP G PP
Sbjct: 1105 GRPGPQGPPGPAGEKGAPGEKGPQGPAG-----RDGLQGPVGLPGPAGPVG-----PPGE 1154
Query: 475 PQKLADVAAP-------------PGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFA- 520
++ P P GP P P P G+ R G +F
Sbjct: 1155 DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPR---GQQGLFGQ 1211
Query: 521 ---ESPGGKTRSAGSASTAGAPPSELFPGPGERSLVG----FGPPVPAKDTETRERMEAM 573
E P G G G P PGE+ G GPP P A
Sbjct: 1212 KGDEGPRGFPGPPGPVGLQGLPGP-----PGEKGETGDVGQMGPPGPPGPRGPSGAPGAD 1266
Query: 574 EKQIASLTGLVQSALL--RGSEPETPSEKIEGSNGAATPSAPCGSGGRS--SGATPVSGP 629
Q G+ + +G E + G G P G G S SGA GP
Sbjct: 1267 GPQ-GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGP 1325
Query: 630 PPPSASSTPAGQPTAV 645
P P G P V
Sbjct: 1326 KGPPGDDGPKGSPGPV 1341
Score = 37.4 bits (85), Expect = 0.085
Identities = 45/175 (25%), Positives = 51/175 (29%), Gaps = 55/175 (31%)
Query: 471 PPSSPQKLADVAAP-PGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRS 529
PP + DV P GPP P P SG P P + P G +
Sbjct: 1235 PPGEKGETGDVGQMGPPGPPGPRGP-SGAPGADGP----------------QGPPGGIGN 1277
Query: 530 AGSASTAGAPPSELFPG-PGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSAL 588
G+ G P PG PGE GPP P
Sbjct: 1278 PGAVGEKGEPGEAGEPGLPGEG-----GPPGP---------------------------- 1304
Query: 589 LRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVS--GPPPPSASSTPAGQ 641
+G E G+ G P P G G PV G P P PAGQ
Sbjct: 1305 -KGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ 1358
Score = 37.4 bits (85), Expect = 0.085
Identities = 54/192 (28%), Positives = 62/192 (32%), Gaps = 26/192 (13%)
Query: 456 GGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGS 515
G GGP G S P A GPP P P +GSP F D G
Sbjct: 1297 GEGGPPGPKGERGEKGESGPSGAA-------GPPGPKGPPGDDGPKGSPGPVGFPGDPGP 1349
Query: 516 SSVFAESPGGKTRSAGSASTAGAPPSELFPGP-GERSLVG----FGPPVPAKDTETRERM 570
P G+ G G P PGP GE G GPP PA E R+
Sbjct: 1350 PG--EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA-GPEGRQGE 1406
Query: 571 EAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPP 630
+ G A L G +T +G+ G P G G G + G P
Sbjct: 1407 K----------GAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPG-PVGEQGLPGSP 1455
Query: 631 PPSASSTPAGQP 642
P P G P
Sbjct: 1456 GPDGPPGPMGPP 1467
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 48.5 bits (114), Expect = 4e-05
Identities = 57/186 (30%), Positives = 70/186 (37%), Gaps = 36/186 (19%)
Query: 484 PPG-----GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGA 538
PPG GPP P P + G+ RQ + G + AE P GKT G AG
Sbjct: 1358 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG--AEGPPGKTGPVGPQGPAGK 1415
Query: 539 PPSE---LFPGP-GERSLVGF----GPP----VPAKDTETRERMEAMEKQIASLTGLVQS 586
P E PGP GE+ L G GPP P + EK L GL+
Sbjct: 1416 PGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1475
Query: 587 ALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPP-----------SAS 635
+G + + +GS GA G GG A P+ P PP S
Sbjct: 1476 PGEQGEKGDRGLPGTQGSPGAK------GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1529
Query: 636 STPAGQ 641
+ PAGQ
Sbjct: 1530 TGPAGQ 1535
Score = 41.2 bits (95), Expect = 0.006
Identities = 86/361 (23%), Positives = 103/361 (28%), Gaps = 95/361 (26%)
Query: 305 SGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVS-- 362
+G P PG G P R PP G P E G P QG+S
Sbjct: 972 TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031
Query: 363 PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPG 422
P+ + R + L G L GEG P + G A AG P PG
Sbjct: 1032 DGPAGL---RGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG-PIGLPG 1087
Query: 423 AGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLADVA 482
G G GP G P P V
Sbjct: 1088 RPG----------------------------PQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1119
Query: 483 APPGGPPPPHSPYSGPPSR-------GSPVRQSFRKDSGSSSVFAESPGGKTRSAGSAST 535
P G P P + +G P G P ++ + D G + P G G
Sbjct: 1120 GPVGLPGP--AGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGPPGLQGPVGA 1172
Query: 536 AGAPPSELFPGP----------GERSLVGF-GPPVPAKDTETRERMEAMEKQIASLTGLV 584
G + PGP G+ GF GPP P L GL
Sbjct: 1173 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----------------IGLQGL- 1214
Query: 585 QSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTA 644
P P EK G NG P P G G GP P+ + P G P +
Sbjct: 1215 ---------PGPPGEK--GENGDVGPMGPPGPPG-------PRGPQGPNGADGPQGPPGS 1256
Query: 645 V 645
V
Sbjct: 1257 V 1257
Score = 39.7 bits (91), Expect = 0.017
Identities = 45/167 (26%), Positives = 55/167 (32%), Gaps = 19/167 (11%)
Query: 487 GPPPPHS------PYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPP 540
GPP P P GP S G+ G V + P G T G GA
Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV--QGPPGPTGKPGKRGRPGADG 598
Query: 541 SELFPG-PGERSLVGFG--PPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETP 597
PG PG + GF P +P ER G+ RG + E
Sbjct: 599 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM------RGEDGEIG 652
Query: 598 SEKIEGSNGAATPSAPCGSGGRSS--GATPVSGPPPPSASSTPAGQP 642
+ G G P G+ G G V GPP P + P G+P
Sbjct: 653 PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 699
Score = 39.3 bits (90), Expect = 0.022
Identities = 91/375 (24%), Positives = 112/375 (29%), Gaps = 71/375 (18%)
Query: 292 RRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRP-----PSYAGSP-- 344
R L AP L G P G P + S + GS + GRP P AG
Sbjct: 1044 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1103
Query: 345 -----VHHAAERLG-----GAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEG 394
A R G G P G + SP ++ ++ SK KGE
Sbjct: 1104 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD-----KGEN 1158
Query: 395 LYADPYGLLHE-GRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYK 453
P GL G +A G+P G ++G ++
Sbjct: 1159 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG-----------------DEGARG 1201
Query: 454 AAGGGGPLYGDGYGFRLPPSSPQKLADVAAP-PGGPPPPHSPYSGPPSRGSPVRQSFRKD 512
G GP+ G PP + DV P GPP P P GP P
Sbjct: 1202 FPGPPGPI--GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP-QGPNGADGP-------- 1250
Query: 513 SGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEA 572
+ P G S G G P PGP + VG GP E E+ EA
Sbjct: 1251 --------QGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG-GPK-----GERGEKGEA 1296
Query: 573 MEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGG-----RSSGATPVS 627
A G G + G G P G G G
Sbjct: 1297 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1356
Query: 628 GPPPPSASSTPAGQP 642
GPP PS + P G P
Sbjct: 1357 GPPGPSGEAGPPGPP 1371
Score = 34.3 bits (77), Expect = 0.72
Identities = 43/180 (23%), Positives = 57/180 (31%), Gaps = 33/180 (18%)
Query: 476 QKLADVAAPPG----GPPPPHSPYS--GPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRS 529
QK PG GPP P P GPP P P G
Sbjct: 439 QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT----------------GPPGDPGD 482
Query: 530 AGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALL 589
G G P ++ PGP L+ +P + + + Q A ++Q A +
Sbjct: 483 RGPPGRPGLPGADGLPGPPGTMLM-----LPFRYGGDGSKGPTISAQEAQAQAILQQARI 537
Query: 590 RGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATP-----VSGPPPPSASSTPAGQPTA 644
P P + G G G+ G S P V GPP P+ G+P A
Sbjct: 538 ALRGPPGPMG-LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGA 596
Score = 33.1 bits (74), Expect = 1.6
Identities = 33/124 (26%), Positives = 42/124 (33%), Gaps = 7/124 (5%)
Query: 525 GKTRSAGSASTAGAPPSELFPG-PGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGL 583
G + AG G P +PG G + GF P P + E R A + G
Sbjct: 838 GPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF-PGFPGANGEKGARGVAGKPGPRGQRGP 896
Query: 584 VQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPV-----SGPPPPSASSTP 638
RG+ T +G++G P P G G PV GPP P
Sbjct: 897 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 956
Query: 639 AGQP 642
G P
Sbjct: 957 PGHP 960
Score = 32.3 bits (72), Expect = 2.7
Identities = 49/186 (26%), Positives = 62/186 (33%), Gaps = 26/186 (13%)
Query: 465 GYGFRLPPSSPQKLADVAAPPGGPPP-PHSPYSGPPSRGSPVRQSFRKDSGSSSVFAE-S 522
G+ + P P + P G P + GPP G P Q +G +
Sbjct: 967 GFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP--GPPGEQGLPGAAGKEGAKGDPG 1024
Query: 523 PGGKTRSAGSASTAGAPPSELFPG----PGERSLVG-FGPPVPAKDTETRERMEAMEKQI 577
P G + G A G P PG PG + G GPP P E+
Sbjct: 1025 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG--------ERGS 1076
Query: 578 ASLTGLVQSALLRGSE-PETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASS 636
A G + G + P P+ G GA P G GR PV P P +
Sbjct: 1077 AGTAGPIGLPGRPGPQGPPGPA----GEKGAPGEKGPQGPAGRDGVQGPVGLPGP----A 1128
Query: 637 TPAGQP 642
PAG P
Sbjct: 1129 GPAGSP 1134
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 48.5 bits (114), Expect = 4e-05
Identities = 57/186 (30%), Positives = 70/186 (37%), Gaps = 36/186 (19%)
Query: 484 PPG-----GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGA 538
PPG GPP P P + G+ RQ + G + AE P GKT G AG
Sbjct: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG--AEGPPGKTGPVGPQGPAGK 1364
Query: 539 PPSE---LFPGP-GERSLVGF----GPP----VPAKDTETRERMEAMEKQIASLTGLVQS 586
P E PGP GE+ L G GPP P + EK L GL+
Sbjct: 1365 PGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1424
Query: 587 ALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPP-----------SAS 635
+G + + +GS GA G GG A P+ P PP S
Sbjct: 1425 PGEQGEKGDRGLPGTQGSPGAK------GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1478
Query: 636 STPAGQ 641
+ PAGQ
Sbjct: 1479 TGPAGQ 1484
Score = 41.2 bits (95), Expect = 0.006
Identities = 86/361 (23%), Positives = 103/361 (28%), Gaps = 95/361 (26%)
Query: 305 SGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVS-- 362
+G P PG G P R PP G P E G P QG+S
Sbjct: 921 TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980
Query: 363 PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPG 422
P+ + R + L G L GEG P + G A AG P PG
Sbjct: 981 DGPAGL---RGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG-PIGLPG 1036
Query: 423 AGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLADVA 482
G G GP G P P V
Sbjct: 1037 RPG----------------------------PQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1068
Query: 483 APPGGPPPPHSPYSGPPSR-------GSPVRQSFRKDSGSSSVFAESPGGKTRSAGSAST 535
P G P P + +G P G P ++ + D G + P G G
Sbjct: 1069 GPVGLPGP--AGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGPPGLQGPVGA 1121
Query: 536 AGAPPSELFPGP----------GERSLVGF-GPPVPAKDTETRERMEAMEKQIASLTGLV 584
G + PGP G+ GF GPP P L GL
Sbjct: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----------------IGLQGL- 1163
Query: 585 QSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTA 644
P P EK G NG P P G G GP P+ + P G P +
Sbjct: 1164 ---------PGPPGEK--GENGDVGPMGPPGPPG-------PRGPQGPNGADGPQGPPGS 1205
Query: 645 V 645
V
Sbjct: 1206 V 1206
Score = 39.7 bits (91), Expect = 0.017
Identities = 45/167 (26%), Positives = 55/167 (32%), Gaps = 19/167 (11%)
Query: 487 GPPPPHS------PYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPP 540
GPP P P GP S G+ G V + P G T G GA
Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV--QGPPGPTGKPGKRGRPGADG 547
Query: 541 SELFPG-PGERSLVGFG--PPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETP 597
PG PG + GF P +P ER G+ RG + E
Sbjct: 548 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM------RGEDGEIG 601
Query: 598 SEKIEGSNGAATPSAPCGSGGRSS--GATPVSGPPPPSASSTPAGQP 642
+ G G P G+ G G V GPP P + P G+P
Sbjct: 602 PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 648
Score = 39.3 bits (90), Expect = 0.022
Identities = 91/375 (24%), Positives = 112/375 (29%), Gaps = 71/375 (18%)
Query: 292 RRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRP-----PSYAGSP-- 344
R L AP L G P G P + S + GS + GRP P AG
Sbjct: 993 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1052
Query: 345 -----VHHAAERLG-----GAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEG 394
A R G G P G + SP ++ ++ SK KGE
Sbjct: 1053 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD-----KGEN 1107
Query: 395 LYADPYGLLHE-GRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYK 453
P GL G +A G+P G ++G ++
Sbjct: 1108 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG-----------------DEGARG 1150
Query: 454 AAGGGGPLYGDGYGFRLPPSSPQKLADVAAP-PGGPPPPHSPYSGPPSRGSPVRQSFRKD 512
G GP+ G PP + DV P GPP P P GP P
Sbjct: 1151 FPGPPGPI--GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP-QGPNGADGP-------- 1199
Query: 513 SGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEA 572
+ P G S G G P PGP + VG GP E E+ EA
Sbjct: 1200 --------QGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG-GPK-----GERGEKGEA 1245
Query: 573 MEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGG-----RSSGATPVS 627
A G G + G G P G G G
Sbjct: 1246 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1305
Query: 628 GPPPPSASSTPAGQP 642
GPP PS + P G P
Sbjct: 1306 GPPGPSGEAGPPGPP 1320
Score = 34.3 bits (77), Expect = 0.72
Identities = 43/180 (23%), Positives = 57/180 (31%), Gaps = 33/180 (18%)
Query: 476 QKLADVAAPPG----GPPPPHSPYS--GPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRS 529
QK PG GPP P P GPP P P G
Sbjct: 388 QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT----------------GPPGDPGD 431
Query: 530 AGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALL 589
G G P ++ PGP L+ +P + + + Q A ++Q A +
Sbjct: 432 RGPPGRPGLPGADGLPGPPGTMLM-----LPFRYGGDGSKGPTISAQEAQAQAILQQARI 486
Query: 590 RGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATP-----VSGPPPPSASSTPAGQPTA 644
P P + G G G+ G S P V GPP P+ G+P A
Sbjct: 487 ALRGPPGPMG-LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGA 545
Score = 33.1 bits (74), Expect = 1.6
Identities = 33/124 (26%), Positives = 42/124 (33%), Gaps = 7/124 (5%)
Query: 525 GKTRSAGSASTAGAPPSELFPG-PGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGL 583
G + AG G P +PG G + GF P P + E R A + G
Sbjct: 787 GPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF-PGFPGANGEKGARGVAGKPGPRGQRGP 845
Query: 584 VQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPV-----SGPPPPSASSTP 638
RG+ T +G++G P P G G PV GPP P
Sbjct: 846 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905
Query: 639 AGQP 642
G P
Sbjct: 906 PGHP 909
Score = 32.3 bits (72), Expect = 2.7
Identities = 49/186 (26%), Positives = 62/186 (33%), Gaps = 26/186 (13%)
Query: 465 GYGFRLPPSSPQKLADVAAPPGGPPP-PHSPYSGPPSRGSPVRQSFRKDSGSSSVFAE-S 522
G+ + P P + P G P + GPP G P Q +G +
Sbjct: 916 GFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP--GPPGEQGLPGAAGKEGAKGDPG 973
Query: 523 PGGKTRSAGSASTAGAPPSELFPG----PGERSLVG-FGPPVPAKDTETRERMEAMEKQI 577
P G + G A G P PG PG + G GPP P E+
Sbjct: 974 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG--------ERGS 1025
Query: 578 ASLTGLVQSALLRGSE-PETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASS 636
A G + G + P P+ G GA P G GR PV P P +
Sbjct: 1026 AGTAGPIGLPGRPGPQGPPGPA----GEKGAPGEKGPQGPAGRDGVQGPVGLPGP----A 1077
Query: 637 TPAGQP 642
PAG P
Sbjct: 1078 GPAGSP 1083
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 48.5 bits (114), Expect = 4e-05
Identities = 57/186 (30%), Positives = 70/186 (37%), Gaps = 36/186 (19%)
Query: 484 PPG-----GPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGA 538
PPG GPP P P + G+ RQ + G + AE P GKT G AG
Sbjct: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG--AEGPPGKTGPVGPQGPAGK 1403
Query: 539 PPSE---LFPGP-GERSLVGF----GPP----VPAKDTETRERMEAMEKQIASLTGLVQS 586
P E PGP GE+ L G GPP P + EK L GL+
Sbjct: 1404 PGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1463
Query: 587 ALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPP-----------SAS 635
+G + + +GS GA G GG A P+ P PP S
Sbjct: 1464 PGEQGEKGDRGLPGTQGSPGAK------GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1517
Query: 636 STPAGQ 641
+ PAGQ
Sbjct: 1518 TGPAGQ 1523
Score = 41.2 bits (95), Expect = 0.006
Identities = 86/361 (23%), Positives = 103/361 (28%), Gaps = 95/361 (26%)
Query: 305 SGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVS-- 362
+G P PG G P R PP G P E G P QG+S
Sbjct: 960 TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019
Query: 363 PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPG 422
P+ + R + L G L GEG P + G A AG P PG
Sbjct: 1020 DGPAGL---RGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG-PIGLPG 1075
Query: 423 AGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLADVA 482
G G GP G P P V
Sbjct: 1076 RPG----------------------------PQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1107
Query: 483 APPGGPPPPHSPYSGPPSR-------GSPVRQSFRKDSGSSSVFAESPGGKTRSAGSAST 535
P G P P + +G P G P ++ + D G + P G G
Sbjct: 1108 GPVGLPGP--AGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGPPGLQGPVGA 1160
Query: 536 AGAPPSELFPGP----------GERSLVGF-GPPVPAKDTETRERMEAMEKQIASLTGLV 584
G + PGP G+ GF GPP P L GL
Sbjct: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----------------IGLQGL- 1202
Query: 585 QSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTA 644
P P EK G NG P P G G GP P+ + P G P +
Sbjct: 1203 ---------PGPPGEK--GENGDVGPMGPPGPPG-------PRGPQGPNGADGPQGPPGS 1244
Query: 645 V 645
V
Sbjct: 1245 V 1245
Score = 39.7 bits (91), Expect = 0.017
Identities = 45/167 (26%), Positives = 55/167 (32%), Gaps = 19/167 (11%)
Query: 487 GPPPPHS------PYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPP 540
GPP P P GP S G+ G V + P G T G GA
Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV--QGPPGPTGKPGKRGRPGADG 586
Query: 541 SELFPG-PGERSLVGFG--PPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETP 597
PG PG + GF P +P ER G+ RG + E
Sbjct: 587 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM------RGEDGEIG 640
Query: 598 SEKIEGSNGAATPSAPCGSGGRSS--GATPVSGPPPPSASSTPAGQP 642
+ G G P G+ G G V GPP P + P G+P
Sbjct: 641 PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 687
Score = 39.3 bits (90), Expect = 0.022
Identities = 91/375 (24%), Positives = 112/375 (29%), Gaps = 71/375 (18%)
Query: 292 RRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGSPSRSRLSYAGGRP-----PSYAGSP-- 344
R L AP L G P G P + S + GS + GRP P AG
Sbjct: 1032 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1091
Query: 345 -----VHHAAERLG-----GAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGEG 394
A R G G P G + SP ++ ++ SK KGE
Sbjct: 1092 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD-----KGEN 1146
Query: 395 LYADPYGLLHE-GRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYK 453
P GL G +A G+P G ++G ++
Sbjct: 1147 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG-----------------DEGARG 1189
Query: 454 AAGGGGPLYGDGYGFRLPPSSPQKLADVAAP-PGGPPPPHSPYSGPPSRGSPVRQSFRKD 512
G GP+ G PP + DV P GPP P P GP P
Sbjct: 1190 FPGPPGPI--GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP-QGPNGADGP-------- 1238
Query: 513 SGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEA 572
+ P G S G G P PGP + VG GP E E+ EA
Sbjct: 1239 --------QGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG-GPK-----GERGEKGEA 1284
Query: 573 MEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGG-----RSSGATPVS 627
A G G + G G P G G G
Sbjct: 1285 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1344
Query: 628 GPPPPSASSTPAGQP 642
GPP PS + P G P
Sbjct: 1345 GPPGPSGEAGPPGPP 1359
Score = 34.3 bits (77), Expect = 0.72
Identities = 43/180 (23%), Positives = 57/180 (31%), Gaps = 33/180 (18%)
Query: 476 QKLADVAAPPG----GPPPPHSPYS--GPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRS 529
QK PG GPP P P GPP P P G
Sbjct: 427 QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT----------------GPPGDPGD 470
Query: 530 AGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALL 589
G G P ++ PGP L+ +P + + + Q A ++Q A +
Sbjct: 471 RGPPGRPGLPGADGLPGPPGTMLM-----LPFRYGGDGSKGPTISAQEAQAQAILQQARI 525
Query: 590 RGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATP-----VSGPPPPSASSTPAGQPTA 644
P P + G G G+ G S P V GPP P+ G+P A
Sbjct: 526 ALRGPPGPMG-LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGA 584
Score = 33.1 bits (74), Expect = 1.6
Identities = 33/124 (26%), Positives = 42/124 (33%), Gaps = 7/124 (5%)
Query: 525 GKTRSAGSASTAGAPPSELFPG-PGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGL 583
G + AG G P +PG G + GF P P + E R A + G
Sbjct: 826 GPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF-PGFPGANGEKGARGVAGKPGPRGQRGP 884
Query: 584 VQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPV-----SGPPPPSASSTP 638
RG+ T +G++G P P G G PV GPP P
Sbjct: 885 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944
Query: 639 AGQP 642
G P
Sbjct: 945 PGHP 948
Score = 32.3 bits (72), Expect = 2.7
Identities = 49/186 (26%), Positives = 62/186 (33%), Gaps = 26/186 (13%)
Query: 465 GYGFRLPPSSPQKLADVAAPPGGPPP-PHSPYSGPPSRGSPVRQSFRKDSGSSSVFAE-S 522
G+ + P P + P G P + GPP G P Q +G +
Sbjct: 955 GFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP--GPPGEQGLPGAAGKEGAKGDPG 1012
Query: 523 PGGKTRSAGSASTAGAPPSELFPG----PGERSLVG-FGPPVPAKDTETRERMEAMEKQI 577
P G + G A G P PG PG + G GPP P E+
Sbjct: 1013 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG--------ERGS 1064
Query: 578 ASLTGLVQSALLRGSE-PETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASS 636
A G + G + P P+ G GA P G GR PV P P +
Sbjct: 1065 AGTAGPIGLPGRPGPQGPPGPA----GEKGAPGEKGPQGPAGRDGVQGPVGLPGP----A 1116
Query: 637 TPAGQP 642
PAG P
Sbjct: 1117 GPAGSP 1122
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 48.5 bits (114), Expect = 4e-05
Identities = 55/187 (29%), Positives = 67/187 (35%), Gaps = 23/187 (12%)
Query: 455 AGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPY-SGPPSRGSPVRQSFRKDS 513
AGGGG +G G GF + GGPP + +G P S + DS
Sbjct: 67 AGGGGGGFGGGGGFGGGGGGG---GGGSFGGGGPPGLGGLFQAGMPKLRSTANRD--NDS 121
Query: 514 GSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAM 573
G S PGG++ SA S P P PG RS GPP P R RM
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRS----GPPEP-----QRNRMPPP 172
Query: 574 EKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPS 633
+ S + + P TP + +P P G S G TP PP P
Sbjct: 173 RPDVGSKPDSIPPPV-----PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTP---PPFPG 224
Query: 634 ASSTPAG 640
T G
Sbjct: 225 NRGTALG 231
Score = 43.5 bits (101), Expect = 0.001
Identities = 54/177 (30%), Positives = 63/177 (35%), Gaps = 49/177 (27%)
Query: 472 PSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAG 531
PS+P+ A APP PPPP P GPP SSS E+P R+
Sbjct: 295 PSTPRPSASSQAPP-PPPPPSRP--GPPPL-----------PPSSSGNDETPRLPQRNLS 340
Query: 532 SASTAGAPPS-----ELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQS 586
+S+ PS L P P ER PP P +D R
Sbjct: 341 LSSSTPPLPSPGRSGPLPPPPSER------PPPPVRDPPGRS------------------ 376
Query: 587 ALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTP-AGQP 642
G P P GS A P+ P RS +P SGP PP P AG P
Sbjct: 377 ----GPLPPPPPVSRNGSTSRALPATP-QLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428
Score = 39.7 bits (91), Expect = 0.017
Identities = 91/370 (24%), Positives = 120/370 (32%), Gaps = 51/370 (13%)
Query: 288 SSPTRRLNNLSPAPHLASGSPPPGLPSGLPS---GLQSGSPSRSRLSYAGG-RPPSYAGS 343
S P N P P GS P +P +PS +QS +R GG R PS +
Sbjct: 159 SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT 218
Query: 344 PVHHAAER---LGGAPAAQGVSPSPSAILERRDVKPDEDLA---------SKAGGMVLVK 391
P R LGG Q S S R + P A G +
Sbjct: 219 PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278
Query: 392 GEGLYADP-----YGLLHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSD 446
E + P + R S ++ A P P G S + + Q +
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN 338
Query: 447 LEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPV- 505
L + PL G LPP PP PPP P PP R P+
Sbjct: 339 L-----SLSSSTPPLPSPGRSGPLPP-----------PPSERPPP--PVRDPPGRSGPLP 380
Query: 506 -RQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDT 564
++ +S +P +RS + +G P P P +R G PP P T
Sbjct: 381 PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP----PLPPDRPSAG-APPPPPPST 435
Query: 565 ETRERME--AMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSG 622
R + E + S + L EP + K S A S GS R G
Sbjct: 436 SIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESR-SGSNRRERG 494
Query: 623 ATPVSGPPPP 632
A P+ PP P
Sbjct: 495 APPL--PPIP 502
Score = 35.8 bits (81), Expect = 0.25
Identities = 42/188 (22%), Positives = 57/188 (30%), Gaps = 30/188 (15%)
Query: 835 PPPNNLLSQSPKKVTAETDFNKSVDFEMPPPSPPLNLHELSGPAEGASLTPKGGNPTKGL 894
P P+ L P S+ E PP PP N S + + P
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313
Query: 895 DTPGKRSVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKA 954
PG + + S D L + L + P L ++
Sbjct: 314 SRPGPPPLPPS-------------------SSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354
Query: 955 HPGPAPTPDHKPP--KAPHGQKA-APRTEPSGRRGSDELTVP-------RYRTEKPSKSP 1004
P P P + PP + P G+ P P R GS +P R + P P
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414
Query: 1005 PPP-PPRR 1011
PP PP R
Sbjct: 415 RPPLPPDR 422
Score = 33.9 bits (76), Expect = 0.94
Identities = 17/59 (28%), Positives = 24/59 (40%)
Query: 956 PGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFP 1014
P P+ + PP P + P PS + +P+ S +PP P P RS P
Sbjct: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
Score = 32.3 bits (72), Expect = 2.7
Identities = 48/180 (26%), Positives = 59/180 (32%), Gaps = 24/180 (13%)
Query: 485 PGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPP---- 540
PG PPP G G +RQS S S P +R+ PP
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274
Query: 541 ----SELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTG---LVQSALLRGSE 593
E P P ++ PPVP+ + S G L S+
Sbjct: 275 PSIHREAVPPPPPQN---NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331
Query: 594 PETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSG--PPP----PSASSTPAGQPTAVSR 647
P P + S ++TP P S GRS P PPP P S P P VSR
Sbjct: 332 PRLPQRNL--SLSSSTPPLP--SPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 48.5 bits (114), Expect = 4e-05
Identities = 55/187 (29%), Positives = 67/187 (35%), Gaps = 23/187 (12%)
Query: 455 AGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPY-SGPPSRGSPVRQSFRKDS 513
AGGGG +G G GF + GGPP + +G P S + DS
Sbjct: 67 AGGGGGGFGGGGGFGGGGGGG---GGGSFGGGGPPGLGGLFQAGMPKLRSTANRD--NDS 121
Query: 514 GSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAM 573
G S PGG++ SA S P P PG RS GPP P R RM
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRS----GPPEP-----QRNRMPPP 172
Query: 574 EKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPS 633
+ S + + P TP + +P P G S G TP PP P
Sbjct: 173 RPDVGSKPDSIPPPV-----PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTP---PPFPG 224
Query: 634 ASSTPAG 640
T G
Sbjct: 225 NRGTALG 231
Score = 43.5 bits (101), Expect = 0.001
Identities = 54/177 (30%), Positives = 63/177 (35%), Gaps = 49/177 (27%)
Query: 472 PSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAG 531
PS+P+ A APP PPPP P GPP SSS E+P R+
Sbjct: 295 PSTPRPSASSQAPP-PPPPPSRP--GPPPL-----------PPSSSGNDETPRLPQRNLS 340
Query: 532 SASTAGAPPS-----ELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQS 586
+S+ PS L P P ER PP P +D R
Sbjct: 341 LSSSTPPLPSPGRSGPLPPPPSER------PPPPVRDPPGRS------------------ 376
Query: 587 ALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTP-AGQP 642
G P P GS A P+ P RS +P SGP PP P AG P
Sbjct: 377 ----GPLPPPPPVSRNGSTSRALPATP-QLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428
Score = 39.7 bits (91), Expect = 0.017
Identities = 91/370 (24%), Positives = 120/370 (32%), Gaps = 51/370 (13%)
Query: 288 SSPTRRLNNLSPAPHLASGSPPPGLPSGLPS---GLQSGSPSRSRLSYAGG-RPPSYAGS 343
S P N P P GS P +P +PS +QS +R GG R PS +
Sbjct: 159 SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT 218
Query: 344 PVHHAAER---LGGAPAAQGVSPSPSAILERRDVKPDEDLA---------SKAGGMVLVK 391
P R LGG Q S S R + P A G +
Sbjct: 219 PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278
Query: 392 GEGLYADP-----YGLLHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSD 446
E + P + R S ++ A P P G S + + Q +
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN 338
Query: 447 LEDSLYKAAGGGGPLYGDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPV- 505
L + PL G LPP PP PPP P PP R P+
Sbjct: 339 L-----SLSSSTPPLPSPGRSGPLPP-----------PPSERPPP--PVRDPPGRSGPLP 380
Query: 506 -RQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDT 564
++ +S +P +RS + +G P P P +R G PP P T
Sbjct: 381 PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP----PLPPDRPSAG-APPPPPPST 435
Query: 565 ETRERME--AMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSG 622
R + E + S + L EP + K S A S GS R G
Sbjct: 436 SIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESR-SGSNRRERG 494
Query: 623 ATPVSGPPPP 632
A P+ PP P
Sbjct: 495 APPL--PPIP 502
Score = 35.8 bits (81), Expect = 0.25
Identities = 42/188 (22%), Positives = 57/188 (30%), Gaps = 30/188 (15%)
Query: 835 PPPNNLLSQSPKKVTAETDFNKSVDFEMPPPSPPLNLHELSGPAEGASLTPKGGNPTKGL 894
P P+ L P S+ E PP PP N S + + P
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313
Query: 895 DTPGKRSVDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKA 954
PG + + S D L + L + P L ++
Sbjct: 314 SRPGPPPLPPS-------------------SSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354
Query: 955 HPGPAPTPDHKPP--KAPHGQKA-APRTEPSGRRGSDELTVP-------RYRTEKPSKSP 1004
P P P + PP + P G+ P P R GS +P R + P P
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414
Query: 1005 PPP-PPRR 1011
PP PP R
Sbjct: 415 RPPLPPDR 422
Score = 33.9 bits (76), Expect = 0.94
Identities = 17/59 (28%), Positives = 24/59 (40%)
Query: 956 PGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFP 1014
P P+ + PP P + P PS + +P+ S +PP P P RS P
Sbjct: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
Score = 32.3 bits (72), Expect = 2.7
Identities = 48/180 (26%), Positives = 59/180 (32%), Gaps = 24/180 (13%)
Query: 485 PGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPP---- 540
PG PPP G G +RQS S S P +R+ PP
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274
Query: 541 ----SELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTG---LVQSALLRGSE 593
E P P ++ PPVP+ + S G L S+
Sbjct: 275 PSIHREAVPPPPPQN---NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331
Query: 594 PETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSG--PPP----PSASSTPAGQPTAVSR 647
P P + S ++TP P S GRS P PPP P S P P VSR
Sbjct: 332 PRLPQRNL--SLSSSTPPLP--SPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387
>gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapiens]
Length = 1343
Score = 48.5 bits (114), Expect = 4e-05
Identities = 131/596 (21%), Positives = 199/596 (33%), Gaps = 91/596 (15%)
Query: 203 LDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEA---RNVFYELEDVRDIQDRSIIKIYR 259
L TLHAL+ + PQ +LK L+ D + RN + + R + R
Sbjct: 689 LSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTALRNPNIQRQPSRQSERP------R 742
Query: 260 KEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNN---LSPAPHLASGSPPPGLPSGL 316
+P+ P + + +R +S R LN+ ++ P PPP P G
Sbjct: 743 PQPVVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGG- 801
Query: 317 PSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVSPSPS-AILERRDVK 375
+ + RPP SP + + P + +S + S ++L+ +
Sbjct: 802 -----------GKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDG 850
Query: 376 PDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSL 435
P L S + + G+ LLH + SL AA G P G +GS S+
Sbjct: 851 PGGRLNSSSVSNLAAVGD--------LLHSSQASLTAALG---LRPAPAGRLSQGSGSSI 899
Query: 436 STYSAAALQSDLEDS-----------------LYKAAGGGGPLYGDGYGF-RLPPSSPQK 477
+ Q + + AA G GP G G G PPSS
Sbjct: 900 TAAGMRLSQMGVTTDGVPAQQLRIPLSFQNPLFHMAADGPGPPGGHGGGGGHGPPSSHHH 959
Query: 478 LADVAAPPGGPPP-----PHSPYSGPPSRGS----PVRQSFRKDSGSSSVFAESPGGKTR 528
GG PP P YS S P S S F S TR
Sbjct: 960 HHHHHHHRGGEPPGDTFAPFHGYSKSEDLSSGVPKPPAASILHSHSYSDEFGPSGTDFTR 1019
Query: 529 -------------SAGSASTAGAPPSELFPGPGERSLVGFG----PPVPAKDTETRERME 571
S + P+ PG G G G PP + + +
Sbjct: 1020 RQLSLQDNLQHMLSPPQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQRGKSQQLTVS 1079
Query: 572 AMEKQIASLTGLVQSA--LLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGP 629
A +K S L+QS + P S EGS G + S G GG T
Sbjct: 1080 AAQKPRPSSGNLLQSPEPSYGPARPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQHSQ 1139
Query: 630 PPPSASSTPAGQPTAVSRLQMQLHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRT 689
P + + T V+ + HL SA + + +L++ ES +K
Sbjct: 1140 TPSTLNPTMPASERTVAWVSNMPHLSADIESA-HIEREEYKLKEYSKSMDESRLDRVKEY 1198
Query: 690 EAELSMRVSEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEKIQR 745
E E+ ++ L +EE R L+ EE ++ L + +E+ ++
Sbjct: 1199 EEEI--------HSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEK 1246
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 48.1 bits (113), Expect = 5e-05
Identities = 93/439 (21%), Positives = 158/439 (35%), Gaps = 78/439 (17%)
Query: 460 PLYGDGYGFRLPPSSPQKLADVAAPP---GGPPPPHSPYSGPPSRGSPVRQSFRKDSGSS 516
P+ G+ P SP + + P GGP PP P S P + Q+ + +
Sbjct: 112 PMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGP 171
Query: 517 SVFAESPGGKTRS---AGSASTAGAPPSELFP--GPGERSLVGFGPPVPAKDTETRERME 571
S F+ + R+ A G P E G+R+L G + + +++ +
Sbjct: 172 SPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQ 231
Query: 572 AMEKQIA--------SLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGA 623
++Q Q AL+ + P P ++ G + P GGR S A
Sbjct: 232 QQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPA-PGGRPSPA 290
Query: 624 TPVSGPPP------PSASSTPAGQPTAVSRLQMQL------------------------- 652
P + PP PS GQP+ V +LQ +
Sbjct: 291 PPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRL 350
Query: 653 ------HLRGLQNSASDLRGQLQ-----QLRKLQLQN------QESVRALLKRTEAELSM 695
++ L+N L L+ +L+ L+L N QE V + + T E ++
Sbjct: 351 QARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETAL 410
Query: 696 RVSEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVP 755
R + L+ R + E+ + + E Q+ + S+ + +D HR V
Sbjct: 411 NSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVA 470
Query: 756 GPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRC 815
G +++L + + A+ Q K R+E E ++ L E + +G K
Sbjct: 471 GK--------IQKLSKAVATWHANTEREQKK--ETERIEKERMRRLMAEDE--EGYRKLI 518
Query: 816 RGVTD-TLAQIRRQVDEGV 833
D LA + +Q DE V
Sbjct: 519 DQKKDRRLAYLLQQTDEYV 537
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,949,224
Number of Sequences: 37866
Number of extensions: 3462219
Number of successful extensions: 36748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 1483
Number of HSP's that attempted gapping in prelim test: 24269
Number of HSP's gapped (non-prelim): 12128
length of query: 1183
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1070
effective length of database: 13,968,660
effective search space: 14946466200
effective search space used: 14946466200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.