Guide to the Human Genome
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Search of human proteins with 114431246

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|114431246 keratin 25D [Homo sapiens]
         (464 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|114431246 keratin 25D [Homo sapiens]                               919   0.0  
gi|153945736 keratin 27 [Homo sapiens]                                697   0.0  
gi|31559829 keratin 25 [Homo sapiens]                                 658   0.0  
gi|31559815 keratin 26 [Homo sapiens]                                 608   e-174
gi|195972866 keratin 10 [Homo sapiens]                                468   e-132
gi|192807292 keratin 24 [Homo sapiens]                                460   e-129
gi|4557699 keratin 12 [Homo sapiens]                                  439   e-123
gi|15431310 keratin 14 [Homo sapiens]                                 421   e-118
gi|24430190 keratin 15 [Homo sapiens]                                 415   e-116
gi|4557701 keratin 17 [Homo sapiens]                                  414   e-116
gi|24430192 keratin 16 [Homo sapiens]                                 408   e-114
gi|131412225 keratin 13 isoform a [Homo sapiens]                      403   e-112
gi|131412228 keratin 13 isoform b [Homo sapiens]                      398   e-111
gi|24234699 keratin 19 [Homo sapiens]                                 376   e-104
gi|4504927 keratin 36 [Homo sapiens]                                  343   1e-94
gi|55956899 keratin 9 [Homo sapiens]                                  340   2e-93
gi|94538345 keratin 35 [Homo sapiens]                                 320   1e-87
gi|27894337 keratin 20 [Homo sapiens]                                 320   2e-87
gi|116488398 keratin 32 [Homo sapiens]                                303   2e-82
gi|14917117 keratin 33A [Homo sapiens]                                300   2e-81
gi|14917115 keratin 31 [Homo sapiens]                                 297   2e-80
gi|10337581 type I hair keratin 3B [Homo sapiens]                     294   1e-79
gi|27894339 keratin 23 [Homo sapiens]                                 286   3e-77
gi|40354195 keratin 18 [Homo sapiens]                                 284   1e-76
gi|4557888 keratin 18 [Homo sapiens]                                  284   1e-76
gi|14917119 keratin 34 [Homo sapiens]                                 283   3e-76
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  278   6e-75
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  271   7e-73
gi|55770882 keratin 37 [Homo sapiens]                                 265   9e-71
gi|15431318 keratin 38 [Homo sapiens]                                 263   3e-70

>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  919 bits (2375), Expect = 0.0
 Identities = 464/464 (100%), Positives = 464/464 (100%)

Query: 1   MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60
           MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS
Sbjct: 1   MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60

Query: 61  HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120
           HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG
Sbjct: 61  HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120

Query: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180
           WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE
Sbjct: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180

Query: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240
           NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG
Sbjct: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240

Query: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300
           GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT
Sbjct: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300

Query: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360
           FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH
Sbjct: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360

Query: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS 420
           QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS
Sbjct: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS 420

Query: 421 KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVPF 464
           KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVPF
Sbjct: 421 KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVPF 464


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  697 bits (1798), Expect = 0.0
 Identities = 356/462 (77%), Positives = 400/462 (86%), Gaps = 5/462 (1%)

Query: 1   MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60
           MS++FS+ SR +    G GSVR  +GGAGF   + CG    GS FSCA GG   S  GG 
Sbjct: 1   MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGS--SSAGGY 58

Query: 61  HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120
             G   G+A+C  F G+E GLLSGNEKVTMQNLNDRLASYL+NVRALEEANA+LE+KIKG
Sbjct: 59  GGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKG 118

Query: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180
           WYEK+GPGSCRGLDHDYSRY   I++LKN+IIS+TT+NA+V+LQ DNARL ADDFRLK+E
Sbjct: 119 WYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFE 178

Query: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240
           NEL LHQ+VEADINGLRRVLDELTLCRTD E+Q E+LSEE+ YLKKNHEEEMKALQCAAG
Sbjct: 179 NELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAG 238

Query: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300
           GNVNVEMNAAPGVDL VLLNNMRAEYEALAEQNR+DAEAWFNEKSASLQQQIS D+GA T
Sbjct: 239 GNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATT 298

Query: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360
            AR++L EM+RTLQTLEI+LQSL+ATKHSLECSLTETESNYC QLAQIQAQIGALEEQLH
Sbjct: 299 SARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLH 358

Query: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS 420
           QVRTETEGQKLEYE LLD+KVHLEKEIETYC LIDG+  SCSKSKG+  G PGN +KD S
Sbjct: 359 QVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGY--GGPGNQTKDSS 416

Query: 421 KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRV 462
           KTT+VKTVVEE+D RGKVLSSR+H++EEK++K+ N K EQRV
Sbjct: 417 KTTIVKTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKNEQRV 457


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  658 bits (1697), Expect = 0.0
 Identities = 336/454 (74%), Positives = 381/454 (83%), Gaps = 11/454 (2%)

Query: 1   MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60
           MSL+ S+ SR  C R   GS+R   GG  F   ++CG S  GS FS A GG   S  GG+
Sbjct: 1   MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGG---SSSGGN 57

Query: 61  HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120
             GG      C GF  +E GLLSGNEKVTMQNLNDRLASYLD+V ALEEANA+LE+KIKG
Sbjct: 58  TGGGN----PCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKG 113

Query: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180
           WYEK+GPGSCRGLDHDYSRY   I+DLKN+II+STT+NAN +LQIDNARL ADDFRLKYE
Sbjct: 114 WYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYE 173

Query: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240
           NEL LHQ+VEAD+NGLRRVLDE+TLCRTD E+QYE+LSEEMTYLKKNH+EEM+ LQCAAG
Sbjct: 174 NELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAG 233

Query: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300
           GNVNVEMNAAPGVDL VLLNNMRAEYEALAEQNR+DAEAWFNEKSASLQQQIS D GA T
Sbjct: 234 GNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATT 293

Query: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360
            AR++LTEM+RTLQTLEI+LQSL+ATKHSLECSLTETESNYC QLAQIQAQIGALEEQLH
Sbjct: 294 SARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLH 353

Query: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSPGNSS 416
           QVRTETEGQKLEYE LLD+K+HLEKEIETYC LI GD  +C     KSK +GSG+ G+  
Sbjct: 354 QVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQV 413

Query: 417 KDLSKTTLVKTVVEELDQRGKVLSSRIHSIEEKT 450
           KD +K  +VK V+EE+DQR K+L++R+HS+EEK+
Sbjct: 414 KDPAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  608 bits (1569), Expect = e-174
 Identities = 316/467 (67%), Positives = 368/467 (78%), Gaps = 7/467 (1%)

Query: 1   MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60
           MS + S GSR +C R+G+G  R   GG GF   + C GS A S FSC L G + S     
Sbjct: 1   MSFRLSGGSRRICSRTGSG--RLSGGGTGFVAGNVCVGSGARSSFSCTLEG-ISSGGSFC 57

Query: 61  HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120
           ++GG LG+ AC GF G+E  LLSGNEKVTMQNLNDRLASYLD+V ALEEANA+LE+KIKG
Sbjct: 58  NSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKG 117

Query: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180
            YEK  PGS R  DHDYSRY   IEDLK +I S+T  NA+++LQ DNARL ADDFRLKYE
Sbjct: 118 RYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYE 177

Query: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240
           NEL LH +VEAD +GLRRVLDELTLC TD E+Q E+LSEE+TYLKK+HEEEM+ LQ  AG
Sbjct: 178 NELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAG 237

Query: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300
           GNVNVEMNA PGVDL VLLNNMRAEYE LAEQNRKDAEAWFNE+SA+LQQQIS   GAAT
Sbjct: 238 GNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAAT 297

Query: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360
            AR++LTE++R LQTLEI+LQSLMA KHS ECSL ETE NYC QL QIQ QIG +EEQL 
Sbjct: 298 AARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQ 357

Query: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD----GNSCSKSKGFGSGSPGNSS 416
           Q+RTETEGQKLEYE LLDVK+ LEKEI+ YC L+DG+     ++C KSKG+   + GN +
Sbjct: 358 QIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQA 417

Query: 417 KDLSKTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVP 463
           KD ++ T+VKTVVEELDQ G +LS R+HS+EEK+SK++N   EQRVP
Sbjct: 418 KDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVP 464


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  468 bits (1203), Expect = e-132
 Identities = 252/403 (62%), Positives = 298/403 (73%), Gaps = 8/403 (1%)

Query: 17  GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
           G GS R   G + F GS   GGS  G  F     GG GS  GG   GG  G     GF G
Sbjct: 81  GGGSFRGSYGSSSFGGSY--GGSFGGGSFGGGSFGG-GSFGGGGFGGGGFGGGFGGGFGG 137

Query: 77  SEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHD 136
            +GGLLSGNEKVTMQNLNDRLASYLD VRALEE+N ELE KIK WYEK+G  S +G   D
Sbjct: 138 -DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHG-NSHQGEPRD 195

Query: 137 YSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGL 196
           YS+Y+ TI+DLKN+I++ TT NAN++LQIDNARLAADDFRLKYENE+ L Q+VEADINGL
Sbjct: 196 YSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGL 255

Query: 197 RRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLA 256
           RRVLDELTL + D E+Q ESL+EE+ YLKKNHEEEMK L+  + G+VNVEMNAAPGVDL 
Sbjct: 256 RRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLT 315

Query: 257 VLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTL 316
            LLNNMR++YE LAEQNRKDAEAWFNEKS  L  +I ++    +  +S++TE+RR +Q L
Sbjct: 316 QLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQAL 375

Query: 317 EIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHL 376
           EI+LQS +A K SLE SL ETE  YC QL+QIQAQI ALEEQL Q+R ETE Q  EY+ L
Sbjct: 376 EIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQL 435

Query: 377 LDVKVHLEKEIETYCRLIDGDGNSCSKSKG---FGSGSPGNSS 416
           LD+K+ LE EI+TY  L++G+G+S    +G   FG G  G SS
Sbjct: 436 LDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSS 478



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 3/71 (4%)

Query: 17  GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
           G GS    + G G+ G S+ GG   G   S   GGG     GG + GG+ G  +  G  G
Sbjct: 500 GGGSSGGGSSGGGYGGGSSSGGH--GGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSG-GG 556

Query: 77  SEGGLLSGNEK 87
             GG  SG  K
Sbjct: 557 YGGGSSSGGHK 567



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 26/68 (38%), Positives = 29/68 (42%)

Query: 17  GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
           G GS     GG    G S+ GG   G   S   G G GS  GGS  GG  G ++  G  G
Sbjct: 465 GGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGG 524

Query: 77  SEGGLLSG 84
           S  G   G
Sbjct: 525 SSSGGYGG 532



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 29/73 (39%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 14  LRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG 73
           L  G GS    +GG G  G S  GG   GS    + GGG G   GGS  GG  G ++  G
Sbjct: 452 LLEGEGS----SGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507

Query: 74  FAGS--EGGLLSG 84
            +G    GG  SG
Sbjct: 508 SSGGGYGGGSSSG 520



 Score = 36.2 bits (82), Expect = 0.065
 Identities = 21/64 (32%), Positives = 27/64 (42%)

Query: 17  GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
           G G     + G G+ G S+ GGS  G     +  GG G    G + GG+ G        G
Sbjct: 486 GHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGG 545

Query: 77  SEGG 80
           S GG
Sbjct: 546 SSGG 549



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 2/71 (2%)

Query: 16  SGAGSVRPLNGGA--GFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG 73
           SG GS    +GG   G +G    GGS  G       GGG  S   G  + G  G  +  G
Sbjct: 478 SGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGG 537

Query: 74  FAGSEGGLLSG 84
             G  GG  SG
Sbjct: 538 GGGGYGGGSSG 548



 Score = 32.3 bits (72), Expect = 0.94
 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 6/79 (7%)

Query: 6   SNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGA 65
           S+G  H     G G      GG G  GSS  G S  G     + GG  GS  GG   G +
Sbjct: 482 SSGGGH-----GGGHGGSSGGGYG-GGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSS 535

Query: 66  LGNAACIGFAGSEGGLLSG 84
            G     G   S GG  SG
Sbjct: 536 GGGGGGYGGGSSGGGSSSG 554



 Score = 32.3 bits (72), Expect = 0.94
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%)

Query: 6   SNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGA 65
           S+G        G G      GG G+ G S+ GGS +G  +    GGG  S    S + G+
Sbjct: 518 SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGY----GGGSSSGGHKSSSSGS 573

Query: 66  LGNAACIG 73
           +G ++  G
Sbjct: 574 VGESSSKG 581



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 3/71 (4%)

Query: 16  SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG-- 73
           SG G     + G G+ G S+ GGS  G       GG  G   GG  +GG        G  
Sbjct: 459 SGGGGRGGGSFGGGYGGGSSGGGSSGGGHGG-GHGGSSGGGYGGGSSGGGSSGGGYGGGS 517

Query: 74  FAGSEGGLLSG 84
            +G  GG  SG
Sbjct: 518 SSGGHGGSSSG 528


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  460 bits (1184), Expect = e-129
 Identities = 267/499 (53%), Positives = 330/499 (66%), Gaps = 59/499 (11%)

Query: 5   FSNGSRHVCLRSGAGSVRPLNGGAGFAG-----SSACGGSVAGSEFSCALGGGLGSVPG- 58
           FS+GSR      G  S +   GGA         S A GGS  G   SC++GGG G   G 
Sbjct: 27  FSSGSR---CGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGASGS 83

Query: 59  ------GSHAGGALGNAACIGFAGS-----------------------EGGLLSGNEKVT 89
                 GS  GG  G     GF GS                       +GGL SG EK T
Sbjct: 84  GTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQT 143

Query: 90  MQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRG-LDHDYSRYHLTIEDLK 148
           MQNLNDRLA+YLD VRALEEAN +LE KIK WY+KYGPGS  G    DYS+Y+  IEDL+
Sbjct: 144 MQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLR 203

Query: 149 NKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRT 208
           N+II++T  NA +IL IDNARLAADDFRLKYENEL L Q+VEADINGLR+VLD+LT+ R+
Sbjct: 204 NQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRS 263

Query: 209 DQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEA 268
           D E+Q ES +EE+ YL+KNHEEEMK +Q ++GG V VEMNAAPG DL  LLN+MRA+YE 
Sbjct: 264 DLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEE 323

Query: 269 LAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKH 328
           LAEQNR++AE  FN++SASLQ QIS D+GAAT A++++TE++RTLQ LEI+LQS +A K 
Sbjct: 324 LAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKS 383

Query: 329 SLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIE 388
           SLE +L +TE+ Y  QL++IQ QI ALEE++ Q+  ET+ Q  EY+ LLD+K  LE EIE
Sbjct: 384 SLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIE 443

Query: 389 TYCRLIDGDGNSCSKSK--GFGSGSPGNSSKDL-----------------SKTTLVKTVV 429
           TY RL+DG+G   S ++  G  SGS    S+DL                 SKT + KT+V
Sbjct: 444 TYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTIV 503

Query: 430 EELDQRGKVLSSRIHSIEE 448
           EEL   GKV+SS++ SI E
Sbjct: 504 EELVD-GKVVSSQVSSISE 521


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  439 bits (1128), Expect = e-123
 Identities = 244/443 (55%), Positives = 311/443 (70%), Gaps = 18/443 (4%)

Query: 16  SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGG----LGSVPGGSHAGGALGNAAC 71
           S A      +G  G +GSS  GG  AG  +  ALGGG    LG   GGS  GG+LG    
Sbjct: 58  SAASMFGSSSGFGGGSGSSMAGGLGAG--YGRALGGGSFGGLGMGFGGSPGGGSLGI--- 112

Query: 72  IGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCR 131
              +G++GGLLSG+EK TMQNLNDRLASYLD VRALEEAN ELE KI+ WYE  G G+  
Sbjct: 113 --LSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTAD 170

Query: 132 GLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEA 191
               DYS+Y+  IEDL+NKIIS++  NA ++LQIDNARLAA+DFR+KYENEL L Q VEA
Sbjct: 171 ASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEA 230

Query: 192 DINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAP 251
           DINGLRRVLDELTL RTD E+Q ESL+EE+ Y+KKNHE+E+++ +    G V+VEM+AAP
Sbjct: 231 DINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAP 290

Query: 252 GVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRR 311
           GVDL  LLN+MRA+YE +AEQNRKDAEAWF EKS  L+++IS ++     ++S++T++RR
Sbjct: 291 GVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRR 350

Query: 312 TLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKL 371
             Q LEI+LQS +A K SLE SL E E +YC QL+Q+Q  I  LE QL QVR + E Q +
Sbjct: 351 AFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNV 410

Query: 372 EYEHLLDVKVHLEKEIETYCRLIDGDG------NSCSKSKGFGSGSPGNSSKDLSKTTLV 425
           +++ LL+VK  LE EIETY RL+DG+        S   +         +SSKD +KT  +
Sbjct: 411 DHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKI 470

Query: 426 KTVVEELDQRGKVLSSRIHSIEE 448
           KTVV+E+   G+V+SS++  IEE
Sbjct: 471 KTVVQEM-VNGEVVSSQVQEIEE 492


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  421 bits (1081), Expect = e-118
 Identities = 236/424 (55%), Positives = 297/424 (70%), Gaps = 19/424 (4%)

Query: 27  GAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGGLLSGNE 86
           G G+ G  +   S  GS F    GGGLG+  GG   GG         FAG +G LL G+E
Sbjct: 66  GGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGG---------FAGGDG-LLVGSE 115

Query: 87  KVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIED 146
           KVTMQNLNDRLASYLD VRALEEANA+LE KI+ WY++  P   +    DYS Y  TIED
Sbjct: 116 KVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIK----DYSPYFKTIED 171

Query: 147 LKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLC 206
           L+NKI+++T  NANV+LQIDNARLAADDFR KYE EL L  +VEADINGLRRVLDELTL 
Sbjct: 172 LRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLA 231

Query: 207 RTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEY 266
           R D E+Q ESL EE+ YLKKNHEEEM AL+   GG+VNVEM+AAPGVDL+ +LN MR +Y
Sbjct: 232 RADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQY 291

Query: 267 EALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMAT 326
           E +AE+NRKDAE WF  K+  L ++++ +S      +S+++E+RRT+Q LEI+LQS ++ 
Sbjct: 292 EKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSM 351

Query: 327 KHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKE 386
           K SLE SL ET+  YC QLAQIQ  IG++EEQL Q+R E E Q  EY+ LLDVK  LE+E
Sbjct: 352 KASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQE 411

Query: 387 IETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDL-SKTTLVKTVVEELDQRGKVLSSRIHS 445
           I TY RL++G+    S S+ F SGS   SS+D+ S +  ++T V ++   GKV+S+    
Sbjct: 412 IATYRRLLEGEDAHLSSSQ-FSSGS--QSSRDVTSSSRQIRTKVMDVHD-GKVVSTHEQV 467

Query: 446 IEEK 449
           +  K
Sbjct: 468 LRTK 471


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  415 bits (1067), Expect = e-116
 Identities = 226/406 (55%), Positives = 280/406 (68%), Gaps = 12/406 (2%)

Query: 16  SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFA 75
           SG G  R ++  +    SS  GG   G    C  GGG GSV GG   GG +G     GF 
Sbjct: 36  SGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGG-VGGGFGGGFG 94

Query: 76  GSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDH 135
           G +GGLLSGNEK+TMQNLNDRLASYLD VRALEEANA+LE KI  WY+K  P S    + 
Sbjct: 95  GGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSP---EC 151

Query: 136 DYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADING 195
           DYS+Y  TIE+L++KI+++T  N+ VIL+IDNARLAADDFRLKYENEL L Q VEADING
Sbjct: 152 DYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADING 211

Query: 196 LRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDL 255
           LRRVLDELTL RTD E+Q E L+EE+ YLKKNHEEEMK       G VNVEM+AAPGVDL
Sbjct: 212 LRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDL 271

Query: 256 AVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQT 315
             +L  MR +YEA+AE+NR+D EAWF  K+  L ++++ ++     +++++T++RRT+Q 
Sbjct: 272 TRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQE 331

Query: 316 LEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEH 375
           LEI+LQS ++ K  LE SL ETE  Y TQL QIQ  IG LE QL ++R E E Q  EY+ 
Sbjct: 332 LEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKM 391

Query: 376 LLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFG-----SGSPGNSS 416
           LLD+K  LE+EI TY  L++G     +K  G G     SG  G+SS
Sbjct: 392 LLDIKTRLEQEIATYRSLLEGQD---AKMAGIGIREASSGGGGSSS 434


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  414 bits (1065), Expect = e-116
 Identities = 230/439 (52%), Positives = 296/439 (67%), Gaps = 34/439 (7%)

Query: 20  SVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGN-------AACI 72
           S+R     +   GSS  GG    S  SC L GGLG+      + G LG+       ++C 
Sbjct: 4   SIRQFTSSSSIKGSSGLGGG--SSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCY 61

Query: 73  GFAGSEG---------GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYE 123
            F    G         GLL+G EK TMQNLNDRLASYLD VRALEEAN ELE KI+ WY+
Sbjct: 62  SFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQ 121

Query: 124 KYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENEL 183
           +  PG  R    DYS+Y+ TIE+L+NKI+++T  NAN++LQIDNARLAADDFR K+E E 
Sbjct: 122 RQAPGPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQ 177

Query: 184 TLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNV 243
            L  +VEADINGLRRVLDELTL R D E+Q E+L EE+ YLKKNHEEEM AL+   GG +
Sbjct: 178 ALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEI 237

Query: 244 NVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFAR 303
           NVEM+AAPGVDL+ +LN MR +YE +AE+NRKDAE WF  K+  L ++++ +S      +
Sbjct: 238 NVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGK 297

Query: 304 SQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVR 363
           S+++E+RRT+Q LEI+LQS ++ K SLE +L ETE+ YC QL+QIQ  IG++EEQL Q+R
Sbjct: 298 SEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLR 357

Query: 364 TETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTT 423
            E E Q  EY+ LLDVK  LE+EI TY RL++G+    ++ K           K+   T 
Sbjct: 358 CEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYK-----------KEPVTTR 406

Query: 424 LVKTVVEELDQRGKVLSSR 442
            V+T+VEE+ Q GKV+SSR
Sbjct: 407 QVRTIVEEV-QDGKVISSR 424


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  408 bits (1049), Expect = e-114
 Identities = 224/389 (57%), Positives = 274/389 (70%), Gaps = 6/389 (1%)

Query: 20  SVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEG 79
           S R  +GGA   G    GG  + S F    GGG G   G    GG LG     GFAG +G
Sbjct: 53  SSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGG-LGAGFGGGFAGGDG 111

Query: 80  GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139
            LL G+EKVTMQNLNDRLASYLD VRALEEANA+LE KI+ WY++  P   +    DYS 
Sbjct: 112 -LLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIK----DYSP 166

Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199
           Y  TIEDL+NKII++T  NA  ILQIDNARLAADDFR KYE+EL L Q VEAD+NGLRRV
Sbjct: 167 YFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRV 226

Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259
           LDELTL RTD E+Q E L EE+ YL+KNHEEEM AL+   GG+VNVEM+AAPGVDL+ +L
Sbjct: 227 LDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRIL 286

Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319
           N MR +YE +AE+NR+DAE WF  K+  L ++++ +S     +RS++TE+RR LQ LEI+
Sbjct: 287 NEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIE 346

Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379
           LQS ++ K SLE SL ET+  YC QL+QIQ  IG++EEQL Q+R E E Q  EY+ LLDV
Sbjct: 347 LQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDV 406

Query: 380 KVHLEKEIETYCRLIDGDGNSCSKSKGFG 408
           K  LE+EI TY RL++G+    S  +  G
Sbjct: 407 KTRLEQEIATYRRLLEGEDAHLSSQQASG 435


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  403 bits (1035), Expect = e-112
 Identities = 221/409 (54%), Positives = 286/409 (69%), Gaps = 11/409 (2%)

Query: 20  SVRPLNGGA--GFAGSSACG-GSVAGSEFSCALGGGLGSVPGGSHAGGALGNAA--CIGF 74
           S R ++GG+  G+ G  +CG G  AGS F    GGGLG   GG   GG  G  A   + F
Sbjct: 33  STRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDF 92

Query: 75  AGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLD 134
              +GGLL+GNEK+TMQNLNDRLASYL+ VRALEEANA+LE KI+ W+ K  P S    +
Sbjct: 93  GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASP---E 149

Query: 135 HDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADIN 194
            DYS Y+ TIE+L++KI+++T  N  VIL+IDNARLAADDFRLKYENEL L Q+VEADIN
Sbjct: 150 RDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADIN 209

Query: 195 GLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVD 254
           GLRRVLDELTL +TD E+Q ESL+EE+ Y+KKNHEEEMK       G VNVEM+A PG+D
Sbjct: 210 GLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGID 269

Query: 255 LAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQ 314
           L  +L  MR +YEA+AE+NR+DAE WF+ KSA L +++S ++     +++++TE+RRTLQ
Sbjct: 270 LTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQ 329

Query: 315 TLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYE 374
            LEI+LQS ++ K  LE ++ ETE  Y  QL QIQ  I ++E QL ++R+E E Q  EY+
Sbjct: 330 GLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYK 389

Query: 375 HLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTT 423
            LLD+K  LE+EI TY  L++G     +K  GF S +   S +  S TT
Sbjct: 390 MLLDIKTRLEQEIATYRSLLEGQD---AKMIGFPSSAGSVSPRSTSVTT 435


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  398 bits (1022), Expect = e-111
 Identities = 213/382 (55%), Positives = 275/382 (71%), Gaps = 8/382 (2%)

Query: 20  SVRPLNGGA--GFAGSSACG-GSVAGSEFSCALGGGLGSVPGGSHAGGALGNAA--CIGF 74
           S R ++GG+  G+ G  +CG G  AGS F    GGGLG   GG   GG  G  A   + F
Sbjct: 33  STRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDF 92

Query: 75  AGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLD 134
              +GGLL+GNEK+TMQNLNDRLASYL+ VRALEEANA+LE KI+ W+ K  P S    +
Sbjct: 93  GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASP---E 149

Query: 135 HDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADIN 194
            DYS Y+ TIE+L++KI+++T  N  VIL+IDNARLAADDFRLKYENEL L Q+VEADIN
Sbjct: 150 RDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADIN 209

Query: 195 GLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVD 254
           GLRRVLDELTL +TD E+Q ESL+EE+ Y+KKNHEEEMK       G VNVEM+A PG+D
Sbjct: 210 GLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGID 269

Query: 255 LAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQ 314
           L  +L  MR +YEA+AE+NR+DAE WF+ KSA L +++S ++     +++++TE+RRTLQ
Sbjct: 270 LTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQ 329

Query: 315 TLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYE 374
            LEI+LQS ++ K  LE ++ ETE  Y  QL QIQ  I ++E QL ++R+E E Q  EY+
Sbjct: 330 GLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYK 389

Query: 375 HLLDVKVHLEKEIETYCRLIDG 396
            LLD+K  LE+EI TY  L++G
Sbjct: 390 MLLDIKTRLEQEIATYRSLLEG 411


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  376 bits (966), Expect = e-104
 Identities = 206/402 (51%), Positives = 267/402 (66%), Gaps = 35/402 (8%)

Query: 17  GAGSVR----------PLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGAL 66
           G GSVR           ++GG+G  G S        S  S A GGG G V   S      
Sbjct: 19  GGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTASD----- 73

Query: 67  GNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYG 126
                        GLL+GNEK+TMQNLNDRLASYLD VRALE AN ELE KI+ WY+K G
Sbjct: 74  -------------GLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQG 120

Query: 127 PGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLH 186
           PG  R    DYS Y+ TI+DL++KI+ +T  N+ ++LQIDNARLAADDFR K+E E  L 
Sbjct: 121 PGPSR----DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALR 176

Query: 187 QNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVE 246
            +VEADINGLRRVLDELTL RTD E+Q E L EE+ YLKKNHEEE+  L+   GG V+VE
Sbjct: 177 MSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVE 236

Query: 247 MNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQL 306
           +++APG DLA +L++MR++YE +AEQNRKDAEAWF  ++  L ++++  +     +RS++
Sbjct: 237 VDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEV 296

Query: 307 TEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTET 366
           T++RRTLQ LEI+LQS ++ K +LE +L ETE+ +  QLA IQA I  +E QL  VR ++
Sbjct: 297 TDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADS 356

Query: 367 EGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG---NSCSKSK 405
           E Q  EY+ L+D+K  LE+EI TY  L++G     N+ S SK
Sbjct: 357 ERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASK 398


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  343 bits (881), Expect = 1e-94
 Identities = 209/456 (45%), Positives = 275/456 (60%), Gaps = 40/456 (8%)

Query: 9   SRHVCLRS-GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALG 67
           SR   +RS G+  V  L G AG+  S+  G S            GLGS   GS+      
Sbjct: 26  SRVSSIRSVGSCRVPSLAGAAGYISSARSGLS------------GLGSCLPGSYLSSECH 73

Query: 68  NAACIGFAGSEG----GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYE 123
            +   GF GS G    G  +G+EK TMQ LNDRLA+YL+ VR LE  NAELE +I+ WYE
Sbjct: 74  TS---GFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYE 130

Query: 124 KYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENEL 183
              P  C     DY  Y  TIED + KI+ + + NA ++LQIDNA+LAADDFR KYE EL
Sbjct: 131 FQIPYICP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETEL 186

Query: 184 TLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNV 243
           +L Q VEADINGLRR+LDELTLC+ D E Q ESL EE+  LKKNHEEE+  L+C  G  +
Sbjct: 187 SLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRL 246

Query: 244 NVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFAR 303
           NVE++AAP VDL  +L +MR +YEAL E NR+D EAWFN ++  L QQ+   S      +
Sbjct: 247 NVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQ 306

Query: 304 SQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVR 363
           +++ E+RRT+  LEI+LQ+  + ++SLE +L ETE+ Y +QLAQ+Q  I  +E QL ++R
Sbjct: 307 TEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIR 366

Query: 364 TETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD---------GNSCSKSKGFGSGSPGN 414
            + E Q  EY+ LLDVK  LE EI TY  L++G+           +C       S  P  
Sbjct: 367 CDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVP 426

Query: 415 SSKDLSKT------TLVKTVVEELDQRGKVLSSRIH 444
               +  T      T ++T+ EE+ + GKV+SSR H
Sbjct: 427 CVPSVPCTPAPQVGTQIRTITEEI-RDGKVISSREH 461


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  340 bits (871), Expect = 2e-93
 Identities = 196/423 (46%), Positives = 256/423 (60%), Gaps = 23/423 (5%)

Query: 5   FSNGSRHVCLRSGAGSVRPLNGGA---GFAGSSACGGSVAGSE-FSCALGGGLGSVPG-- 58
           +  GS  VC R G GS     GG    GF+ SS  GG   GS  F  A GGG  S  G  
Sbjct: 53  YGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFG 112

Query: 59  ---GSHAGGALGNAACIGFAG----------SEGGLLSGNEKVTMQNLNDRLASYLDNVR 105
              G  +GG  G     GF G           +GG+L+ NEK TMQ LN RLASYLD V+
Sbjct: 113 GGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQ 172

Query: 106 ALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQI 165
           ALEEAN +LE KI+ WY+K GP +   +  +YS Y+ TI+DLK++I+  T  N   +L I
Sbjct: 173 ALEEANNDLENKIQDWYDKKGPAA---IQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDI 229

Query: 166 DNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLK 225
           DN R+  DDFR+K+E E  L Q V+ADINGLR+VLD LT+ ++D E+QYE+L EE+  LK
Sbjct: 230 DNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALK 289

Query: 226 KNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKS 285
           KNH+EEM  L     G+VNVE+N APG DL   LN+MR EYE L  +NRKD E  +  + 
Sbjct: 290 KNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQI 349

Query: 286 ASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQL 345
             ++ ++S        +  ++T++R  +Q LEI+LQS ++ K +LE SL +T++ YC QL
Sbjct: 350 TQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQL 409

Query: 346 AQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSK 405
             IQ QI  LE Q+  VR E E Q  EY  LL +K+ LEKEIETY  L++G G    +S 
Sbjct: 410 QMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG-GQEDFESS 468

Query: 406 GFG 408
           G G
Sbjct: 469 GAG 471



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 10/77 (12%)

Query: 16  SGAGSVRPLNGG-AGFAGSSACGGSVAGSEFSCALGGGLGSV--PGGSHAGGALGNAACI 72
           SG G      GG +G +G +  GGS +G       GGG GS    GGSH GG+       
Sbjct: 538 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGS------- 590

Query: 73  GFAGSEGGLLSGNEKVT 89
           GF G  GG   G E+ +
Sbjct: 591 GFGGESGGSYGGGEEAS 607



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 28/69 (40%), Positives = 32/69 (46%), Gaps = 8/69 (11%)

Query: 17  GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCA-LGGGLGSVPGGSHAGGALGNAACIGFA 75
           G GS     GG+G  G S  GGS  G   S    GGG G   GG H+GG+ G     G +
Sbjct: 499 GGGSGGGYGGGSGSRGGS--GGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGG-----GHS 551

Query: 76  GSEGGLLSG 84
           G  GG   G
Sbjct: 552 GGSGGNYGG 560



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 17  GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
           G GS      G  + G S  GG  +G  +    GGG     GG H+GG+ GN    G +G
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGG-SGGGYGGGSGGGHSGGSGGGHSGGSGGNYG--GGSG 563

Query: 77  SEGG 80
           S GG
Sbjct: 564 SGGG 567



 Score = 36.6 bits (83), Expect = 0.050
 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 17  GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
           G GS      G G+ G S   GS  GS  S   G G G   GGS+ GG   + +  G+ G
Sbjct: 559 GGGSGSGGGSGGGYGGGS---GSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGG 615

Query: 77  SEG 79
             G
Sbjct: 616 GSG 618



 Score = 36.2 bits (82), Expect = 0.065
 Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 10/78 (12%)

Query: 16  SGAGSVRPLNGGAGFAGS------SACGGSVAGSEFSCALGGGLGS--VPGGSHAGGA-L 66
           SGAG +  L G  G  GS         GGS  G       GGG GS    GGS+ GG+  
Sbjct: 468 SGAGKIG-LGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS 526

Query: 67  GNAACIGFAGSEGGLLSG 84
           G  +  G+ G  GG  SG
Sbjct: 527 GGGSGGGYGGGSGGGHSG 544



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 25/69 (36%), Positives = 28/69 (40%), Gaps = 5/69 (7%)

Query: 16  SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFA 75
           S  GS     GG    G     GS  GS  S   G G G   GG + GG+ G     G +
Sbjct: 489 SRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGG-----GHS 543

Query: 76  GSEGGLLSG 84
           G  GG  SG
Sbjct: 544 GGSGGGHSG 552



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 2/66 (3%)

Query: 16  SGAGSVRPLNGGAGFAGSSACG-GSVAGSEFSCALGGGLGSVPGGSHAGGA-LGNAACIG 73
           S  GS     GG+G  G S  G G  +G   S   GGG     GG++ GG+  G  +  G
Sbjct: 512 SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG 571

Query: 74  FAGSEG 79
           + G  G
Sbjct: 572 YGGGSG 577



 Score = 32.7 bits (73), Expect = 0.72
 Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 2/45 (4%)

Query: 16  SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60
           S  GS     GG+GF G S  GGS  G E +   GGG G   G S
Sbjct: 578 SRGGSGGSHGGGSGFGGES--GGSYGGGEEASGSGGGYGGGSGKS 620



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 4/75 (5%)

Query: 17  GAGSVRPLNGGAGFAGSSACGGSVAGSEF--SCALGGGLGSVPGGSHAGGALGNAACIG- 73
           G+G       G  + G S  GG   G     S + GG  GS  GGS  GG  G +   G 
Sbjct: 545 GSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGE 604

Query: 74  -FAGSEGGLLSGNEK 87
             +GS GG   G+ K
Sbjct: 605 EASGSGGGYGGGSGK 619



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)

Query: 25  NGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGGLLSG 84
           + GAG  G    GGS  GS    + GG  GS  GG   GG  G +   G +G   G  SG
Sbjct: 467 SSGAGKIGLGGRGGS-GGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG 525

Query: 85  N 85
           +
Sbjct: 526 S 526



 Score = 30.8 bits (68), Expect = 2.7
 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 16  SGAGSVRPLNGGAGF---AGSSACGGSVAGSEFSCALGGG-LGSVPGGSHAGGA 65
           SG GS     GG+G    +G S  GGS  G E   + GGG   S  GG + GG+
Sbjct: 564 SGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGS 617


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  320 bits (821), Expect = 1e-87
 Identities = 182/409 (44%), Positives = 254/409 (62%), Gaps = 33/409 (8%)

Query: 13  CLRSG--AGSVRPLNGGAGFA-------GSSACG----GSVAGSEFSCALGGGLGS---- 55
           CL++G  +GS++   G +G +        SS+C       VA S  +C++G G  S    
Sbjct: 5   CLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRAT 64

Query: 56  -------VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALE 108
                  +P G  A    G     G      G+L+GNEK TMQ+LNDRLA YL+ VR LE
Sbjct: 65  SCLPALCLPAGGFATSYSGGGGWFG-----EGILTGNEKETMQSLNDRLAGYLEKVRQLE 119

Query: 109 EANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNA 168
           + NA LE +I+ W E+  P  C     DY  Y  TIE+L+ K + S   NA ++++IDNA
Sbjct: 120 QENASLESRIREWCEQQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNA 175

Query: 169 RLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNH 228
           +LAADDFR KYE E++L Q VE+DINGLRR+LD+LTLC++D E Q ESL EE+  LKKNH
Sbjct: 176 KLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNH 235

Query: 229 EEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASL 288
           EEE+ +L+C  G  +NVE++AAP VDL  +L  MR +YE L E NR+DAE W + +S  L
Sbjct: 236 EEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEEL 295

Query: 289 QQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQI 348
            QQ+   S      ++++ E+RRT+  LEI+LQ+  + + +LE +L ETE+ Y +QLAQ+
Sbjct: 296 NQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQM 355

Query: 349 QAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD 397
           Q  I  +E QL ++R + E Q  EY+ LLDV+  LE EI TY  L++ +
Sbjct: 356 QCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESE 404


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  320 bits (819), Expect = 2e-87
 Identities = 181/403 (44%), Positives = 264/403 (65%), Gaps = 15/403 (3%)

Query: 51  GGLGSVPGGSHAGGA-LGNAACIGFAGSE----GGLLSGNEKVTMQNLNDRLASYLDNVR 105
           G   SV GG+   G  + N+      GS+    G L  GNEK+ MQNLNDRLASYL+ VR
Sbjct: 30  GTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVR 89

Query: 106 ALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQI 165
            LE++N++LE +IK WYE   P + R    DYS Y+  IE+L+++I  +   NA  +LQI
Sbjct: 90  TLEQSNSKLEVQIKQWYETNAPRAGR----DYSAYYRQIEELRSQIKDAQLQNARCVLQI 145

Query: 166 DNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLK 225
           DNA+LAA+DFRLKYE E  +   VEAD+ GL +V D+LTL +TD E+Q E L++++  LK
Sbjct: 146 DNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLK 205

Query: 226 KNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKS 285
           K H+EE+  L    G  VNVE++AAPG++L V++N MR +YE +A++N ++A+  F  ++
Sbjct: 206 KEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQT 265

Query: 286 ASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQL 345
           A LQQQ++ ++        QLTE+RRT Q+LEI+LQS ++ K SLE +L ET++ Y +QL
Sbjct: 266 AVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQL 325

Query: 346 AQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSK 405
           A +Q+ + +LE QL Q+R+  E Q  EY  LLD+K  LE+EI TY RL++G+    ++ +
Sbjct: 326 ANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQ 385

Query: 406 GFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVLSSRIHSIEE 448
                      +D+ KT  +KTVV+E+   GKV+SS +  +EE
Sbjct: 386 -----LSTLEERDIKKTRKIKTVVQEVVD-GKVVSSEVKEVEE 422


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  303 bits (777), Expect = 2e-82
 Identities = 166/345 (48%), Positives = 224/345 (64%), Gaps = 16/345 (4%)

Query: 70  ACIGFAGSEG-------GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWY 122
           A  G +GS G       G  +GNEK TMQ LNDRLASYL  VR LE+ NAELE +I    
Sbjct: 73  AASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRI---- 128

Query: 123 EKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENE 182
           ++        +  DY  +  TIE+L+ KI+ +   NA +++ IDNA+LAADDFR KYE E
Sbjct: 129 QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAE 188

Query: 183 LTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGN 242
           L + Q VEADINGLRR+LD+LTLC+ D E Q ESL EE+  LKKNHEEE+ +L+C  G  
Sbjct: 189 LAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDR 248

Query: 243 VNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFA 302
           +N+E++AAP VDL  +L  MR +YEA+ E NR+D E WFN +   L QQ++  S      
Sbjct: 249 LNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNY 308

Query: 303 RSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQV 362
           +S + ++RRT+ TLEI+LQ+  + + SLE +LTE+E+ Y +QLAQ+Q  I  +E QL ++
Sbjct: 309 QSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEI 368

Query: 363 RTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCS 402
           R + E Q  EY+ LLDV+  LE EI TY  L++ +      N CS
Sbjct: 369 RADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCS 413


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  300 bits (768), Expect = 2e-81
 Identities = 162/338 (47%), Positives = 224/338 (66%), Gaps = 15/338 (4%)

Query: 80  GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139
           G  +G+EK TMQ LNDRLASYL+ VR LE  NAELE  I+   ++  P  C      Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCAS----YQS 105

Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199
           Y  TIE+L+ KI+ S + NA +++QIDNA+LA+DDFR KYE EL+L Q VE+DINGLRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165

Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259
           LDELTLCR+D E Q ESL EE+  LK+NHE+E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225

Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319
           N  R++YEAL E NR++ E WF  ++  L +Q+   S      ++++ E+RRT+  LEI+
Sbjct: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q  I  +E QL ++R++ E Q  EY+ LLDV
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 380 KVHLEKEIETYCRLIDGDG-----------NSCSKSKG 406
           +  LE EI TY  L++ +            N+C KS G
Sbjct: 346 RARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTG 383


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  297 bits (760), Expect = 2e-80
 Identities = 160/338 (47%), Positives = 224/338 (66%), Gaps = 15/338 (4%)

Query: 80  GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139
           G  +G+EK TMQ LNDRLASYL+ VR LE  NAELE  I+   ++  P  C      Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105

Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199
           Y  TIE+L+ KI+ + + NA +++QIDNA+LAADDFR KY+ EL+L Q VE+DINGLRR+
Sbjct: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165

Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259
           LDELTLC++D E Q ESL EE+  LK NHE+E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225

Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319
           N  R++YEAL E NR++ E WF  ++  L +Q+   S      ++++ E+RRT+  LEI+
Sbjct: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q+ I  +E QL ++R++ E Q  EY+ LLDV
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 380 KVHLEKEIETYCRLIDGDG-----------NSCSKSKG 406
           +  LE EI TY  L++ +            N+CSK  G
Sbjct: 346 RARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIG 383


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  294 bits (752), Expect = 1e-79
 Identities = 155/318 (48%), Positives = 217/318 (68%), Gaps = 4/318 (1%)

Query: 80  GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139
           G  +G+EK TMQ LNDRLASYL+ VR LE  NAELE  I+   ++  P  C      Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105

Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199
           Y  TIE+L+ KI+ S + NA +++QIDNA+LAADDFR KY+ E +L Q VE+DIN LRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRI 165

Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259
           LDELTLCR+D E Q ESL EE+  LK+NHE+E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 166 LDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVL 225

Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319
           N  R +YEAL E NR++ E WF  ++  L +Q+   S      ++++ E+RRT+  LEI+
Sbjct: 226 NETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379
           LQ+    ++SLE +LTE+E+ Y +QL+Q+Q+ I  +E QL ++R++ E Q  EY+ LLDV
Sbjct: 286 LQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 380 KVHLEKEIETYCRLIDGD 397
           +  LE EI TY  L++ +
Sbjct: 346 RARLECEINTYRSLLESE 363


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  286 bits (732), Expect = 3e-77
 Identities = 168/444 (37%), Positives = 253/444 (56%), Gaps = 30/444 (6%)

Query: 9   SRHVCLRSGAGSVRPLNGGAG----FAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGG 64
           S H   ++ + S     GG G    F  +    G   G+  S +        PGGS    
Sbjct: 3   SGHSFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWG-- 60

Query: 65  ALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEK 124
                     +G    LL GN K TMQNLNDRLASYL+ VRALEEAN +LE +I  W+++
Sbjct: 61  ----------SGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQ 110

Query: 125 YGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELT 184
             PGS +    DYS+Y   I  L+ +I+    TNA +IL IDNAR+A DDF LKYENE +
Sbjct: 111 RDPGSKK----DYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHS 166

Query: 185 LHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVN 244
             +++E ++ GLRR LD LT+  TD E + E + +E+  +KK+HE+EM+     +  NVN
Sbjct: 167 FKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVN 226

Query: 245 VEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARS 304
           V+++  P  DL  +L +MR EYE + ++  +D + W+ E+SA++ Q+ +  +   +  + 
Sbjct: 227 VKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPATVQS-RQG 285

Query: 305 QLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRT 364
            + E++RT Q LEI LQ+  +TK +LE  L+ET+S Y  +L  +Q  I   EE+L Q+R 
Sbjct: 286 DIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRH 345

Query: 365 ETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTTL 424
           E E Q  EY+ LL +K HLEKEI TY RL++G+          G+     SS  +S T  
Sbjct: 346 ELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESE--------GTREESKSSMKVSATPK 397

Query: 425 VKTVVEELDQRGKVLSSRIHSIEE 448
           +K + +E    G+++  +++ I++
Sbjct: 398 IKAITQE-TINGRLVLCQVNEIQK 420


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  284 bits (727), Expect = 1e-76
 Identities = 178/421 (42%), Positives = 251/421 (59%), Gaps = 29/421 (6%)

Query: 22  RPLNGGAG-FAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGG 80
           RP++  A  +AG+   G  ++ S  S +  GG+GS        G L      G AG  GG
Sbjct: 27  RPVSSAASVYAGAGGSGSRISVSR-STSFRGGMGS--------GGLATGIAGGLAGM-GG 76

Query: 81  LLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRY 140
           +   NEK TMQ+LNDRLASYLD VR+LE  N  LE KI+   EK GP        D+S Y
Sbjct: 77  IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-----RDWSHY 129

Query: 141 HLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVL 200
              IEDL+ +I ++T  NA ++LQIDNARLAADDFR+KYE EL + Q+VE DI+GLR+V+
Sbjct: 130 FKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVI 189

Query: 201 DELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQC-AAGGNVNVEMNAAPGVDLAVLL 259
           D+  + R   E + E+L EE+ ++KKNHEEE+K LQ   A   + VE++A    DLA ++
Sbjct: 190 DDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIM 249

Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319
            ++RA+Y+ LA +NR++ + +++++       ++  S     A + LTE+RRT+Q+LEI 
Sbjct: 250 ADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEID 309

Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379
           L S+   K SLE SL E E+ Y  Q+ Q+   +  LE +L Q R E + Q  EYE LL++
Sbjct: 310 LDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNI 369

Query: 380 KVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVL 439
           KV LE EI TY RL++ DG   +      S    NS + + KTT  + V       GKV+
Sbjct: 370 KVKLEAEIATYRRLLE-DGEDFNLGDALDS---SNSMQTIQKTTTRRIV------DGKVV 419

Query: 440 S 440
           S
Sbjct: 420 S 420


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  284 bits (727), Expect = 1e-76
 Identities = 178/421 (42%), Positives = 251/421 (59%), Gaps = 29/421 (6%)

Query: 22  RPLNGGAG-FAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGG 80
           RP++  A  +AG+   G  ++ S  S +  GG+GS        G L      G AG  GG
Sbjct: 27  RPVSSAASVYAGAGGSGSRISVSR-STSFRGGMGS--------GGLATGIAGGLAGM-GG 76

Query: 81  LLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRY 140
           +   NEK TMQ+LNDRLASYLD VR+LE  N  LE KI+   EK GP        D+S Y
Sbjct: 77  IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-----RDWSHY 129

Query: 141 HLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVL 200
              IEDL+ +I ++T  NA ++LQIDNARLAADDFR+KYE EL + Q+VE DI+GLR+V+
Sbjct: 130 FKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVI 189

Query: 201 DELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQC-AAGGNVNVEMNAAPGVDLAVLL 259
           D+  + R   E + E+L EE+ ++KKNHEEE+K LQ   A   + VE++A    DLA ++
Sbjct: 190 DDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIM 249

Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319
            ++RA+Y+ LA +NR++ + +++++       ++  S     A + LTE+RRT+Q+LEI 
Sbjct: 250 ADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEID 309

Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379
           L S+   K SLE SL E E+ Y  Q+ Q+   +  LE +L Q R E + Q  EYE LL++
Sbjct: 310 LDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNI 369

Query: 380 KVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVL 439
           KV LE EI TY RL++ DG   +      S    NS + + KTT  + V       GKV+
Sbjct: 370 KVKLEAEIATYRRLLE-DGEDFNLGDALDS---SNSMQTIQKTTTRRIV------DGKVV 419

Query: 440 S 440
           S
Sbjct: 420 S 420


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  283 bits (723), Expect = 3e-76
 Identities = 156/345 (45%), Positives = 223/345 (64%), Gaps = 11/345 (3%)

Query: 80  GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139
           G  +G+EK TMQ LNDRLASYL+ VR LE  NAELE+ I+   ++  P  C      Y  
Sbjct: 92  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPS----YQS 147

Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199
           Y  TIE+L+ KI+ +   NA +++ IDNA+LA+DDFR KY+ E +L   VE+DIN +RR+
Sbjct: 148 YFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRI 207

Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259
           LDELTLC++D E Q ESL EE+  LKKNHEEE+  L+   G  +NVE++ AP VDL  +L
Sbjct: 208 LDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVL 267

Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319
           N  R++YEAL E NR++ E WF  ++  L +Q+   S      ++++ E+RRT+  LEI+
Sbjct: 268 NETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIE 327

Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379
           LQ+    + SLE +LTE+E++Y +QL+Q+Q+ I  +E QL ++R + E Q  EY+ LLDV
Sbjct: 328 LQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDV 387

Query: 380 KVHLEKEIETYCRLIDGDG-----NSCSKSKGFGS--GSPGNSSK 417
           +  LE EI TY  L++ +      N C+ +   G+  G  G S K
Sbjct: 388 RARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPCGTSQK 432


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  278 bits (712), Expect = 6e-75
 Identities = 154/339 (45%), Positives = 217/339 (64%), Gaps = 8/339 (2%)

Query: 68  NAACI--GFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKY 125
           N+ C+    A  E G+ + NEK TMQ LNDRLASYL+ VR+LEE NAELE +I+   E+ 
Sbjct: 69  NSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQD 128

Query: 126 GPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTL 185
            P  C     DY RY  TIEDL+ KI+ +   N+ + +Q+DN +LA DDF+ KYE+EL+L
Sbjct: 129 IPMVCP----DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSL 184

Query: 186 HQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNV 245
            Q +EADI+ L  +L+ELTLC++D E   ESL E++  LKKNHEEE+  L+   G  ++V
Sbjct: 185 RQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSV 244

Query: 246 EMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQ 305
           E++ AP +DL  +L+ MR + E +   NR++AE W   ++  L QQ    +      + +
Sbjct: 245 ELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQME 304

Query: 306 LTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTE 365
           + E++RT   LEI+LQ+  +   SLEC++ ETE+ Y +QLAQIQ  I  LE QL ++R +
Sbjct: 305 ILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCD 364

Query: 366 TEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGN--SCS 402
            E Q  EY+ LLDVK  LE EI TY  L+D + +  SCS
Sbjct: 365 LERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCS 403


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  271 bits (694), Expect = 7e-73
 Identities = 147/314 (46%), Positives = 199/314 (63%), Gaps = 4/314 (1%)

Query: 82  LSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYH 141
           ++ NEK TMQ LN+RLA+YL  VR LE  NAELE KI+    K  P  C     DY  Y+
Sbjct: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147

Query: 142 LTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLD 201
            TIE+L+ KI+ +   N+ ++ QIDN +L ADD R KYE E++L Q VE+D NGL+++L+
Sbjct: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207

Query: 202 ELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNN 261
            LTL + D E Q +SL EE+  LK NH+EE+ +LQC  G  +++E+ AAP  DL  +L  
Sbjct: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267

Query: 262 MRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQ 321
           MR +YE + E NRKD E WFN +   L QQ+   S      + ++ E+RR++ TLE++LQ
Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327

Query: 322 SLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKV 381
           +    + S EC LTETE+ Y   L QIQ+ I  LE QL ++R   E Q  EYE LLDVK 
Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387

Query: 382 HLEKEIETYCRLID 395
            LE EI TY  L++
Sbjct: 388 RLECEITTYRSLLE 401


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  265 bits (676), Expect = 9e-71
 Identities = 152/352 (43%), Positives = 209/352 (59%), Gaps = 14/352 (3%)

Query: 56  VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELE 115
           +PG  H  G +G     G        L+G+EK TM+ LNDRLA+YL+ VR LE+ NAELE
Sbjct: 79  LPGTCHIPGNIGICGAYG-----KNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELE 133

Query: 116 RKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDF 175
             +    + +    C     DY  Y  TIE+L+ KI+ S   NA +I+QIDNA+LAADDF
Sbjct: 134 TTLLERSKCHESTVCP----DYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDF 189

Query: 176 RLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKAL 235
           R+K E+E +LHQ VEAD  G +++LD+ TL + D E Q ESL EE   LK NHE+E+K L
Sbjct: 190 RIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKIL 249

Query: 236 QCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHD 295
           +   G    +E++  P +DL  +L  MRA+YEA+ E N +D E WF  +S  +  Q    
Sbjct: 250 RSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSC 309

Query: 296 SGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGAL 355
           S      +S++ E+R T+  LE++ Q+    K  L+ SL E E  Y T+LAQ+Q+ I  L
Sbjct: 310 SEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNL 369

Query: 356 EEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCS 402
           EEQL ++R + E Q  EY+ LLDVK  LE EI TY  L++ +      N CS
Sbjct: 370 EEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCS 421


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  263 bits (671), Expect = 3e-70
 Identities = 152/354 (42%), Positives = 211/354 (59%), Gaps = 14/354 (3%)

Query: 56  VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELE 115
           +PG  H  G +G     G        L+G+EK TMQ LNDRLA+YL+ VR LE+ NAELE
Sbjct: 79  LPGTCHIPGNIGICGAYG-----ENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELE 133

Query: 116 RKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDF 175
             +    + +    C     DY  Y  TIE+L+ KI+ S   NA +I+QIDNA+LAADDF
Sbjct: 134 ATLLERSKCHESTVCP----DYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDF 189

Query: 176 RLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKAL 235
           R+K E+E +L Q VEAD  G +++LD+ TL + D E Q ESL EE   LK NHE+E+K L
Sbjct: 190 RIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKIL 249

Query: 236 QCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHD 295
           +   G  + +E++  P +DL  +L  MRA+YEA+ E NR+D E WF  +S  +  Q    
Sbjct: 250 RSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSC 309

Query: 296 SGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGAL 355
           S      +S++ E+R T+  LE++ Q+    K  L+ SL E E  + T+LAQ+Q+ I  +
Sbjct: 310 SEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNV 369

Query: 356 EEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCSKS 404
           EEQL ++R + E Q  EY+ LLDVK  LE EI TY  L++ +      N CS S
Sbjct: 370 EEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTS 423


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,089,672
Number of Sequences: 37866
Number of extensions: 788361
Number of successful extensions: 5961
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 177
Number of HSP's successfully gapped in prelim test: 318
Number of HSP's that attempted gapping in prelim test: 3780
Number of HSP's gapped (non-prelim): 1533
length of query: 464
length of database: 18,247,518
effective HSP length: 106
effective length of query: 358
effective length of database: 14,233,722
effective search space: 5095672476
effective search space used: 5095672476
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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