BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|114431246 keratin 25D [Homo sapiens] (464 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|114431246 keratin 25D [Homo sapiens] 919 0.0 gi|153945736 keratin 27 [Homo sapiens] 697 0.0 gi|31559829 keratin 25 [Homo sapiens] 658 0.0 gi|31559815 keratin 26 [Homo sapiens] 608 e-174 gi|195972866 keratin 10 [Homo sapiens] 468 e-132 gi|192807292 keratin 24 [Homo sapiens] 460 e-129 gi|4557699 keratin 12 [Homo sapiens] 439 e-123 gi|15431310 keratin 14 [Homo sapiens] 421 e-118 gi|24430190 keratin 15 [Homo sapiens] 415 e-116 gi|4557701 keratin 17 [Homo sapiens] 414 e-116 gi|24430192 keratin 16 [Homo sapiens] 408 e-114 gi|131412225 keratin 13 isoform a [Homo sapiens] 403 e-112 gi|131412228 keratin 13 isoform b [Homo sapiens] 398 e-111 gi|24234699 keratin 19 [Homo sapiens] 376 e-104 gi|4504927 keratin 36 [Homo sapiens] 343 1e-94 gi|55956899 keratin 9 [Homo sapiens] 340 2e-93 gi|94538345 keratin 35 [Homo sapiens] 320 1e-87 gi|27894337 keratin 20 [Homo sapiens] 320 2e-87 gi|116488398 keratin 32 [Homo sapiens] 303 2e-82 gi|14917117 keratin 33A [Homo sapiens] 300 2e-81 gi|14917115 keratin 31 [Homo sapiens] 297 2e-80 gi|10337581 type I hair keratin 3B [Homo sapiens] 294 1e-79 gi|27894339 keratin 23 [Homo sapiens] 286 3e-77 gi|40354195 keratin 18 [Homo sapiens] 284 1e-76 gi|4557888 keratin 18 [Homo sapiens] 284 1e-76 gi|14917119 keratin 34 [Homo sapiens] 283 3e-76 gi|125490370 type I hair keratin KA36 [Homo sapiens] 278 6e-75 gi|148277620 type I hair keratin KA35 [Homo sapiens] 271 7e-73 gi|55770882 keratin 37 [Homo sapiens] 265 9e-71 gi|15431318 keratin 38 [Homo sapiens] 263 3e-70 >gi|114431246 keratin 25D [Homo sapiens] Length = 464 Score = 919 bits (2375), Expect = 0.0 Identities = 464/464 (100%), Positives = 464/464 (100%) Query: 1 MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60 MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS Sbjct: 1 MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60 Query: 61 HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120 HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG Sbjct: 61 HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120 Query: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE Sbjct: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180 Query: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG Sbjct: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240 Query: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT Sbjct: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300 Query: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH Sbjct: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360 Query: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS 420 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS Sbjct: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS 420 Query: 421 KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVPF 464 KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVPF Sbjct: 421 KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVPF 464 >gi|153945736 keratin 27 [Homo sapiens] Length = 459 Score = 697 bits (1798), Expect = 0.0 Identities = 356/462 (77%), Positives = 400/462 (86%), Gaps = 5/462 (1%) Query: 1 MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60 MS++FS+ SR + G GSVR +GGAGF + CG GS FSCA GG S GG Sbjct: 1 MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGS--SSAGGY 58 Query: 61 HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120 G G+A+C F G+E GLLSGNEKVTMQNLNDRLASYL+NVRALEEANA+LE+KIKG Sbjct: 59 GGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKG 118 Query: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180 WYEK+GPGSCRGLDHDYSRY I++LKN+IIS+TT+NA+V+LQ DNARL ADDFRLK+E Sbjct: 119 WYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFE 178 Query: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240 NEL LHQ+VEADINGLRRVLDELTLCRTD E+Q E+LSEE+ YLKKNHEEEMKALQCAAG Sbjct: 179 NELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAG 238 Query: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300 GNVNVEMNAAPGVDL VLLNNMRAEYEALAEQNR+DAEAWFNEKSASLQQQIS D+GA T Sbjct: 239 GNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATT 298 Query: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360 AR++L EM+RTLQTLEI+LQSL+ATKHSLECSLTETESNYC QLAQIQAQIGALEEQLH Sbjct: 299 SARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLH 358 Query: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS 420 QVRTETEGQKLEYE LLD+KVHLEKEIETYC LIDG+ SCSKSKG+ G PGN +KD S Sbjct: 359 QVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGY--GGPGNQTKDSS 416 Query: 421 KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRV 462 KTT+VKTVVEE+D RGKVLSSR+H++EEK++K+ N K EQRV Sbjct: 417 KTTIVKTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKNEQRV 457 >gi|31559829 keratin 25 [Homo sapiens] Length = 450 Score = 658 bits (1697), Expect = 0.0 Identities = 336/454 (74%), Positives = 381/454 (83%), Gaps = 11/454 (2%) Query: 1 MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60 MSL+ S+ SR C R GS+R GG F ++CG S GS FS A GG S GG+ Sbjct: 1 MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGG---SSSGGN 57 Query: 61 HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120 GG C GF +E GLLSGNEKVTMQNLNDRLASYLD+V ALEEANA+LE+KIKG Sbjct: 58 TGGGN----PCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKG 113 Query: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180 WYEK+GPGSCRGLDHDYSRY I+DLKN+II+STT+NAN +LQIDNARL ADDFRLKYE Sbjct: 114 WYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYE 173 Query: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240 NEL LHQ+VEAD+NGLRRVLDE+TLCRTD E+QYE+LSEEMTYLKKNH+EEM+ LQCAAG Sbjct: 174 NELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAG 233 Query: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300 GNVNVEMNAAPGVDL VLLNNMRAEYEALAEQNR+DAEAWFNEKSASLQQQIS D GA T Sbjct: 234 GNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATT 293 Query: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360 AR++LTEM+RTLQTLEI+LQSL+ATKHSLECSLTETESNYC QLAQIQAQIGALEEQLH Sbjct: 294 SARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLH 353 Query: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSPGNSS 416 QVRTETEGQKLEYE LLD+K+HLEKEIETYC LI GD +C KSK +GSG+ G+ Sbjct: 354 QVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQV 413 Query: 417 KDLSKTTLVKTVVEELDQRGKVLSSRIHSIEEKT 450 KD +K +VK V+EE+DQR K+L++R+HS+EEK+ Sbjct: 414 KDPAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447 >gi|31559815 keratin 26 [Homo sapiens] Length = 468 Score = 608 bits (1569), Expect = e-174 Identities = 316/467 (67%), Positives = 368/467 (78%), Gaps = 7/467 (1%) Query: 1 MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60 MS + S GSR +C R+G+G R GG GF + C GS A S FSC L G + S Sbjct: 1 MSFRLSGGSRRICSRTGSG--RLSGGGTGFVAGNVCVGSGARSSFSCTLEG-ISSGGSFC 57 Query: 61 HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120 ++GG LG+ AC GF G+E LLSGNEKVTMQNLNDRLASYLD+V ALEEANA+LE+KIKG Sbjct: 58 NSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKG 117 Query: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180 YEK PGS R DHDYSRY IEDLK +I S+T NA+++LQ DNARL ADDFRLKYE Sbjct: 118 RYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYE 177 Query: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240 NEL LH +VEAD +GLRRVLDELTLC TD E+Q E+LSEE+TYLKK+HEEEM+ LQ AG Sbjct: 178 NELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAG 237 Query: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300 GNVNVEMNA PGVDL VLLNNMRAEYE LAEQNRKDAEAWFNE+SA+LQQQIS GAAT Sbjct: 238 GNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAAT 297 Query: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360 AR++LTE++R LQTLEI+LQSLMA KHS ECSL ETE NYC QL QIQ QIG +EEQL Sbjct: 298 AARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQ 357 Query: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD----GNSCSKSKGFGSGSPGNSS 416 Q+RTETEGQKLEYE LLDVK+ LEKEI+ YC L+DG+ ++C KSKG+ + GN + Sbjct: 358 QIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQA 417 Query: 417 KDLSKTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVP 463 KD ++ T+VKTVVEELDQ G +LS R+HS+EEK+SK++N EQRVP Sbjct: 418 KDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVP 464 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 468 bits (1203), Expect = e-132 Identities = 252/403 (62%), Positives = 298/403 (73%), Gaps = 8/403 (1%) Query: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76 G GS R G + F GS GGS G F GG GS GG GG G GF G Sbjct: 81 GGGSFRGSYGSSSFGGSY--GGSFGGGSFGGGSFGG-GSFGGGGFGGGGFGGGFGGGFGG 137 Query: 77 SEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHD 136 +GGLLSGNEKVTMQNLNDRLASYLD VRALEE+N ELE KIK WYEK+G S +G D Sbjct: 138 -DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHG-NSHQGEPRD 195 Query: 137 YSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGL 196 YS+Y+ TI+DLKN+I++ TT NAN++LQIDNARLAADDFRLKYENE+ L Q+VEADINGL Sbjct: 196 YSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGL 255 Query: 197 RRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLA 256 RRVLDELTL + D E+Q ESL+EE+ YLKKNHEEEMK L+ + G+VNVEMNAAPGVDL Sbjct: 256 RRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLT 315 Query: 257 VLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTL 316 LLNNMR++YE LAEQNRKDAEAWFNEKS L +I ++ + +S++TE+RR +Q L Sbjct: 316 QLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQAL 375 Query: 317 EIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHL 376 EI+LQS +A K SLE SL ETE YC QL+QIQAQI ALEEQL Q+R ETE Q EY+ L Sbjct: 376 EIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQL 435 Query: 377 LDVKVHLEKEIETYCRLIDGDGNSCSKSKG---FGSGSPGNSS 416 LD+K+ LE EI+TY L++G+G+S +G FG G G SS Sbjct: 436 LDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSS 478 Score = 40.4 bits (93), Expect = 0.003 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76 G GS + G G+ G S+ GG G S GGG GG + GG+ G + G G Sbjct: 500 GGGSSGGGSSGGGYGGGSSSGGH--GGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSG-GG 556 Query: 77 SEGGLLSGNEK 87 GG SG K Sbjct: 557 YGGGSSSGGHK 567 Score = 38.1 bits (87), Expect = 0.017 Identities = 26/68 (38%), Positives = 29/68 (42%) Query: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76 G GS GG G S+ GG G S G G GS GGS GG G ++ G G Sbjct: 465 GGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGG 524 Query: 77 SEGGLLSG 84 S G G Sbjct: 525 SSSGGYGG 532 Score = 37.4 bits (85), Expect = 0.029 Identities = 29/73 (39%), Positives = 34/73 (46%), Gaps = 6/73 (8%) Query: 14 LRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG 73 L G GS +GG G G S GG GS + GGG G GGS GG G ++ G Sbjct: 452 LLEGEGS----SGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507 Query: 74 FAGS--EGGLLSG 84 +G GG SG Sbjct: 508 SSGGGYGGGSSSG 520 Score = 36.2 bits (82), Expect = 0.065 Identities = 21/64 (32%), Positives = 27/64 (42%) Query: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76 G G + G G+ G S+ GGS G + GG G G + GG+ G G Sbjct: 486 GHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGG 545 Query: 77 SEGG 80 S GG Sbjct: 546 SSGG 549 Score = 35.0 bits (79), Expect = 0.14 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 2/71 (2%) Query: 16 SGAGSVRPLNGGA--GFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG 73 SG GS +GG G +G GGS G GGG S G + G G + G Sbjct: 478 SGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGG 537 Query: 74 FAGSEGGLLSG 84 G GG SG Sbjct: 538 GGGGYGGGSSG 548 Score = 32.3 bits (72), Expect = 0.94 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 6/79 (7%) Query: 6 SNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGA 65 S+G H G G GG G GSS G S G + GG GS GG G + Sbjct: 482 SSGGGH-----GGGHGGSSGGGYG-GGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSS 535 Query: 66 LGNAACIGFAGSEGGLLSG 84 G G S GG SG Sbjct: 536 GGGGGGYGGGSSGGGSSSG 554 Score = 32.3 bits (72), Expect = 0.94 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Query: 6 SNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGA 65 S+G G G GG G+ G S+ GGS +G + GGG S S + G+ Sbjct: 518 SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGY----GGGSSSGGHKSSSSGS 573 Query: 66 LGNAACIG 73 +G ++ G Sbjct: 574 VGESSSKG 581 Score = 31.6 bits (70), Expect = 1.6 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 3/71 (4%) Query: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG-- 73 SG G + G G+ G S+ GGS G GG G GG +GG G Sbjct: 459 SGGGGRGGGSFGGGYGGGSSGGGSSGGGHGG-GHGGSSGGGYGGGSSGGGSSGGGYGGGS 517 Query: 74 FAGSEGGLLSG 84 +G GG SG Sbjct: 518 SSGGHGGSSSG 528 >gi|192807292 keratin 24 [Homo sapiens] Length = 525 Score = 460 bits (1184), Expect = e-129 Identities = 267/499 (53%), Positives = 330/499 (66%), Gaps = 59/499 (11%) Query: 5 FSNGSRHVCLRSGAGSVRPLNGGAGFAG-----SSACGGSVAGSEFSCALGGGLGSVPG- 58 FS+GSR G S + GGA S A GGS G SC++GGG G G Sbjct: 27 FSSGSR---CGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGASGS 83 Query: 59 ------GSHAGGALGNAACIGFAGS-----------------------EGGLLSGNEKVT 89 GS GG G GF GS +GGL SG EK T Sbjct: 84 GTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQT 143 Query: 90 MQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRG-LDHDYSRYHLTIEDLK 148 MQNLNDRLA+YLD VRALEEAN +LE KIK WY+KYGPGS G DYS+Y+ IEDL+ Sbjct: 144 MQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLR 203 Query: 149 NKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRT 208 N+II++T NA +IL IDNARLAADDFRLKYENEL L Q+VEADINGLR+VLD+LT+ R+ Sbjct: 204 NQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRS 263 Query: 209 DQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEA 268 D E+Q ES +EE+ YL+KNHEEEMK +Q ++GG V VEMNAAPG DL LLN+MRA+YE Sbjct: 264 DLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEE 323 Query: 269 LAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKH 328 LAEQNR++AE FN++SASLQ QIS D+GAAT A++++TE++RTLQ LEI+LQS +A K Sbjct: 324 LAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKS 383 Query: 329 SLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIE 388 SLE +L +TE+ Y QL++IQ QI ALEE++ Q+ ET+ Q EY+ LLD+K LE EIE Sbjct: 384 SLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIE 443 Query: 389 TYCRLIDGDGNSCSKSK--GFGSGSPGNSSKDL-----------------SKTTLVKTVV 429 TY RL+DG+G S ++ G SGS S+DL SKT + KT+V Sbjct: 444 TYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTIV 503 Query: 430 EELDQRGKVLSSRIHSIEE 448 EEL GKV+SS++ SI E Sbjct: 504 EELVD-GKVVSSQVSSISE 521 >gi|4557699 keratin 12 [Homo sapiens] Length = 494 Score = 439 bits (1128), Expect = e-123 Identities = 244/443 (55%), Positives = 311/443 (70%), Gaps = 18/443 (4%) Query: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGG----LGSVPGGSHAGGALGNAAC 71 S A +G G +GSS GG AG + ALGGG LG GGS GG+LG Sbjct: 58 SAASMFGSSSGFGGGSGSSMAGGLGAG--YGRALGGGSFGGLGMGFGGSPGGGSLGI--- 112 Query: 72 IGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCR 131 +G++GGLLSG+EK TMQNLNDRLASYLD VRALEEAN ELE KI+ WYE G G+ Sbjct: 113 --LSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTAD 170 Query: 132 GLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEA 191 DYS+Y+ IEDL+NKIIS++ NA ++LQIDNARLAA+DFR+KYENEL L Q VEA Sbjct: 171 ASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEA 230 Query: 192 DINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAP 251 DINGLRRVLDELTL RTD E+Q ESL+EE+ Y+KKNHE+E+++ + G V+VEM+AAP Sbjct: 231 DINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAP 290 Query: 252 GVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRR 311 GVDL LLN+MRA+YE +AEQNRKDAEAWF EKS L+++IS ++ ++S++T++RR Sbjct: 291 GVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRR 350 Query: 312 TLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKL 371 Q LEI+LQS +A K SLE SL E E +YC QL+Q+Q I LE QL QVR + E Q + Sbjct: 351 AFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNV 410 Query: 372 EYEHLLDVKVHLEKEIETYCRLIDGDG------NSCSKSKGFGSGSPGNSSKDLSKTTLV 425 +++ LL+VK LE EIETY RL+DG+ S + +SSKD +KT + Sbjct: 411 DHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKI 470 Query: 426 KTVVEELDQRGKVLSSRIHSIEE 448 KTVV+E+ G+V+SS++ IEE Sbjct: 471 KTVVQEM-VNGEVVSSQVQEIEE 492 >gi|15431310 keratin 14 [Homo sapiens] Length = 472 Score = 421 bits (1081), Expect = e-118 Identities = 236/424 (55%), Positives = 297/424 (70%), Gaps = 19/424 (4%) Query: 27 GAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGGLLSGNE 86 G G+ G + S GS F GGGLG+ GG GG FAG +G LL G+E Sbjct: 66 GGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGG---------FAGGDG-LLVGSE 115 Query: 87 KVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIED 146 KVTMQNLNDRLASYLD VRALEEANA+LE KI+ WY++ P + DYS Y TIED Sbjct: 116 KVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIK----DYSPYFKTIED 171 Query: 147 LKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLC 206 L+NKI+++T NANV+LQIDNARLAADDFR KYE EL L +VEADINGLRRVLDELTL Sbjct: 172 LRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLA 231 Query: 207 RTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEY 266 R D E+Q ESL EE+ YLKKNHEEEM AL+ GG+VNVEM+AAPGVDL+ +LN MR +Y Sbjct: 232 RADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQY 291 Query: 267 EALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMAT 326 E +AE+NRKDAE WF K+ L ++++ +S +S+++E+RRT+Q LEI+LQS ++ Sbjct: 292 EKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSM 351 Query: 327 KHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKE 386 K SLE SL ET+ YC QLAQIQ IG++EEQL Q+R E E Q EY+ LLDVK LE+E Sbjct: 352 KASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQE 411 Query: 387 IETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDL-SKTTLVKTVVEELDQRGKVLSSRIHS 445 I TY RL++G+ S S+ F SGS SS+D+ S + ++T V ++ GKV+S+ Sbjct: 412 IATYRRLLEGEDAHLSSSQ-FSSGS--QSSRDVTSSSRQIRTKVMDVHD-GKVVSTHEQV 467 Query: 446 IEEK 449 + K Sbjct: 468 LRTK 471 >gi|24430190 keratin 15 [Homo sapiens] Length = 456 Score = 415 bits (1067), Expect = e-116 Identities = 226/406 (55%), Positives = 280/406 (68%), Gaps = 12/406 (2%) Query: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFA 75 SG G R ++ + SS GG G C GGG GSV GG GG +G GF Sbjct: 36 SGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGG-VGGGFGGGFG 94 Query: 76 GSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDH 135 G +GGLLSGNEK+TMQNLNDRLASYLD VRALEEANA+LE KI WY+K P S + Sbjct: 95 GGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSP---EC 151 Query: 136 DYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADING 195 DYS+Y TIE+L++KI+++T N+ VIL+IDNARLAADDFRLKYENEL L Q VEADING Sbjct: 152 DYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADING 211 Query: 196 LRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDL 255 LRRVLDELTL RTD E+Q E L+EE+ YLKKNHEEEMK G VNVEM+AAPGVDL Sbjct: 212 LRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDL 271 Query: 256 AVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQT 315 +L MR +YEA+AE+NR+D EAWF K+ L ++++ ++ +++++T++RRT+Q Sbjct: 272 TRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQE 331 Query: 316 LEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEH 375 LEI+LQS ++ K LE SL ETE Y TQL QIQ IG LE QL ++R E E Q EY+ Sbjct: 332 LEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKM 391 Query: 376 LLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFG-----SGSPGNSS 416 LLD+K LE+EI TY L++G +K G G SG G+SS Sbjct: 392 LLDIKTRLEQEIATYRSLLEGQD---AKMAGIGIREASSGGGGSSS 434 >gi|4557701 keratin 17 [Homo sapiens] Length = 432 Score = 414 bits (1065), Expect = e-116 Identities = 230/439 (52%), Positives = 296/439 (67%), Gaps = 34/439 (7%) Query: 20 SVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGN-------AACI 72 S+R + GSS GG S SC L GGLG+ + G LG+ ++C Sbjct: 4 SIRQFTSSSSIKGSSGLGGG--SSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCY 61 Query: 73 GFAGSEG---------GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYE 123 F G GLL+G EK TMQNLNDRLASYLD VRALEEAN ELE KI+ WY+ Sbjct: 62 SFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQ 121 Query: 124 KYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENEL 183 + PG R DYS+Y+ TIE+L+NKI+++T NAN++LQIDNARLAADDFR K+E E Sbjct: 122 RQAPGPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQ 177 Query: 184 TLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNV 243 L +VEADINGLRRVLDELTL R D E+Q E+L EE+ YLKKNHEEEM AL+ GG + Sbjct: 178 ALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEI 237 Query: 244 NVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFAR 303 NVEM+AAPGVDL+ +LN MR +YE +AE+NRKDAE WF K+ L ++++ +S + Sbjct: 238 NVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGK 297 Query: 304 SQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVR 363 S+++E+RRT+Q LEI+LQS ++ K SLE +L ETE+ YC QL+QIQ IG++EEQL Q+R Sbjct: 298 SEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLR 357 Query: 364 TETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTT 423 E E Q EY+ LLDVK LE+EI TY RL++G+ ++ K K+ T Sbjct: 358 CEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYK-----------KEPVTTR 406 Query: 424 LVKTVVEELDQRGKVLSSR 442 V+T+VEE+ Q GKV+SSR Sbjct: 407 QVRTIVEEV-QDGKVISSR 424 >gi|24430192 keratin 16 [Homo sapiens] Length = 473 Score = 408 bits (1049), Expect = e-114 Identities = 224/389 (57%), Positives = 274/389 (70%), Gaps = 6/389 (1%) Query: 20 SVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEG 79 S R +GGA G GG + S F GGG G G GG LG GFAG +G Sbjct: 53 SSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGG-LGAGFGGGFAGGDG 111 Query: 80 GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139 LL G+EKVTMQNLNDRLASYLD VRALEEANA+LE KI+ WY++ P + DYS Sbjct: 112 -LLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIK----DYSP 166 Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199 Y TIEDL+NKII++T NA ILQIDNARLAADDFR KYE+EL L Q VEAD+NGLRRV Sbjct: 167 YFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRV 226 Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259 LDELTL RTD E+Q E L EE+ YL+KNHEEEM AL+ GG+VNVEM+AAPGVDL+ +L Sbjct: 227 LDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRIL 286 Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319 N MR +YE +AE+NR+DAE WF K+ L ++++ +S +RS++TE+RR LQ LEI+ Sbjct: 287 NEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIE 346 Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379 LQS ++ K SLE SL ET+ YC QL+QIQ IG++EEQL Q+R E E Q EY+ LLDV Sbjct: 347 LQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDV 406 Query: 380 KVHLEKEIETYCRLIDGDGNSCSKSKGFG 408 K LE+EI TY RL++G+ S + G Sbjct: 407 KTRLEQEIATYRRLLEGEDAHLSSQQASG 435 >gi|131412225 keratin 13 isoform a [Homo sapiens] Length = 458 Score = 403 bits (1035), Expect = e-112 Identities = 221/409 (54%), Positives = 286/409 (69%), Gaps = 11/409 (2%) Query: 20 SVRPLNGGA--GFAGSSACG-GSVAGSEFSCALGGGLGSVPGGSHAGGALGNAA--CIGF 74 S R ++GG+ G+ G +CG G AGS F GGGLG GG GG G A + F Sbjct: 33 STRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDF 92 Query: 75 AGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLD 134 +GGLL+GNEK+TMQNLNDRLASYL+ VRALEEANA+LE KI+ W+ K P S + Sbjct: 93 GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASP---E 149 Query: 135 HDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADIN 194 DYS Y+ TIE+L++KI+++T N VIL+IDNARLAADDFRLKYENEL L Q+VEADIN Sbjct: 150 RDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADIN 209 Query: 195 GLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVD 254 GLRRVLDELTL +TD E+Q ESL+EE+ Y+KKNHEEEMK G VNVEM+A PG+D Sbjct: 210 GLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGID 269 Query: 255 LAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQ 314 L +L MR +YEA+AE+NR+DAE WF+ KSA L +++S ++ +++++TE+RRTLQ Sbjct: 270 LTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQ 329 Query: 315 TLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYE 374 LEI+LQS ++ K LE ++ ETE Y QL QIQ I ++E QL ++R+E E Q EY+ Sbjct: 330 GLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYK 389 Query: 375 HLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTT 423 LLD+K LE+EI TY L++G +K GF S + S + S TT Sbjct: 390 MLLDIKTRLEQEIATYRSLLEGQD---AKMIGFPSSAGSVSPRSTSVTT 435 >gi|131412228 keratin 13 isoform b [Homo sapiens] Length = 420 Score = 398 bits (1022), Expect = e-111 Identities = 213/382 (55%), Positives = 275/382 (71%), Gaps = 8/382 (2%) Query: 20 SVRPLNGGA--GFAGSSACG-GSVAGSEFSCALGGGLGSVPGGSHAGGALGNAA--CIGF 74 S R ++GG+ G+ G +CG G AGS F GGGLG GG GG G A + F Sbjct: 33 STRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDF 92 Query: 75 AGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLD 134 +GGLL+GNEK+TMQNLNDRLASYL+ VRALEEANA+LE KI+ W+ K P S + Sbjct: 93 GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASP---E 149 Query: 135 HDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADIN 194 DYS Y+ TIE+L++KI+++T N VIL+IDNARLAADDFRLKYENEL L Q+VEADIN Sbjct: 150 RDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADIN 209 Query: 195 GLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVD 254 GLRRVLDELTL +TD E+Q ESL+EE+ Y+KKNHEEEMK G VNVEM+A PG+D Sbjct: 210 GLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGID 269 Query: 255 LAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQ 314 L +L MR +YEA+AE+NR+DAE WF+ KSA L +++S ++ +++++TE+RRTLQ Sbjct: 270 LTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQ 329 Query: 315 TLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYE 374 LEI+LQS ++ K LE ++ ETE Y QL QIQ I ++E QL ++R+E E Q EY+ Sbjct: 330 GLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYK 389 Query: 375 HLLDVKVHLEKEIETYCRLIDG 396 LLD+K LE+EI TY L++G Sbjct: 390 MLLDIKTRLEQEIATYRSLLEG 411 >gi|24234699 keratin 19 [Homo sapiens] Length = 400 Score = 376 bits (966), Expect = e-104 Identities = 206/402 (51%), Positives = 267/402 (66%), Gaps = 35/402 (8%) Query: 17 GAGSVR----------PLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGAL 66 G GSVR ++GG+G G S S S A GGG G V S Sbjct: 19 GGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTASD----- 73 Query: 67 GNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYG 126 GLL+GNEK+TMQNLNDRLASYLD VRALE AN ELE KI+ WY+K G Sbjct: 74 -------------GLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQG 120 Query: 127 PGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLH 186 PG R DYS Y+ TI+DL++KI+ +T N+ ++LQIDNARLAADDFR K+E E L Sbjct: 121 PGPSR----DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALR 176 Query: 187 QNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVE 246 +VEADINGLRRVLDELTL RTD E+Q E L EE+ YLKKNHEEE+ L+ GG V+VE Sbjct: 177 MSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVE 236 Query: 247 MNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQL 306 +++APG DLA +L++MR++YE +AEQNRKDAEAWF ++ L ++++ + +RS++ Sbjct: 237 VDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEV 296 Query: 307 TEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTET 366 T++RRTLQ LEI+LQS ++ K +LE +L ETE+ + QLA IQA I +E QL VR ++ Sbjct: 297 TDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADS 356 Query: 367 EGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG---NSCSKSK 405 E Q EY+ L+D+K LE+EI TY L++G N+ S SK Sbjct: 357 ERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASK 398 >gi|4504927 keratin 36 [Homo sapiens] Length = 467 Score = 343 bits (881), Expect = 1e-94 Identities = 209/456 (45%), Positives = 275/456 (60%), Gaps = 40/456 (8%) Query: 9 SRHVCLRS-GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALG 67 SR +RS G+ V L G AG+ S+ G S GLGS GS+ Sbjct: 26 SRVSSIRSVGSCRVPSLAGAAGYISSARSGLS------------GLGSCLPGSYLSSECH 73 Query: 68 NAACIGFAGSEG----GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYE 123 + GF GS G G +G+EK TMQ LNDRLA+YL+ VR LE NAELE +I+ WYE Sbjct: 74 TS---GFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYE 130 Query: 124 KYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENEL 183 P C DY Y TIED + KI+ + + NA ++LQIDNA+LAADDFR KYE EL Sbjct: 131 FQIPYICP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETEL 186 Query: 184 TLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNV 243 +L Q VEADINGLRR+LDELTLC+ D E Q ESL EE+ LKKNHEEE+ L+C G + Sbjct: 187 SLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRL 246 Query: 244 NVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFAR 303 NVE++AAP VDL +L +MR +YEAL E NR+D EAWFN ++ L QQ+ S + Sbjct: 247 NVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQ 306 Query: 304 SQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVR 363 +++ E+RRT+ LEI+LQ+ + ++SLE +L ETE+ Y +QLAQ+Q I +E QL ++R Sbjct: 307 TEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIR 366 Query: 364 TETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD---------GNSCSKSKGFGSGSPGN 414 + E Q EY+ LLDVK LE EI TY L++G+ +C S P Sbjct: 367 CDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVP 426 Query: 415 SSKDLSKT------TLVKTVVEELDQRGKVLSSRIH 444 + T T ++T+ EE+ + GKV+SSR H Sbjct: 427 CVPSVPCTPAPQVGTQIRTITEEI-RDGKVISSREH 461 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 340 bits (871), Expect = 2e-93 Identities = 196/423 (46%), Positives = 256/423 (60%), Gaps = 23/423 (5%) Query: 5 FSNGSRHVCLRSGAGSVRPLNGGA---GFAGSSACGGSVAGSE-FSCALGGGLGSVPG-- 58 + GS VC R G GS GG GF+ SS GG GS F A GGG S G Sbjct: 53 YGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFG 112 Query: 59 ---GSHAGGALGNAACIGFAG----------SEGGLLSGNEKVTMQNLNDRLASYLDNVR 105 G +GG G GF G +GG+L+ NEK TMQ LN RLASYLD V+ Sbjct: 113 GGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQ 172 Query: 106 ALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQI 165 ALEEAN +LE KI+ WY+K GP + + +YS Y+ TI+DLK++I+ T N +L I Sbjct: 173 ALEEANNDLENKIQDWYDKKGPAA---IQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDI 229 Query: 166 DNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLK 225 DN R+ DDFR+K+E E L Q V+ADINGLR+VLD LT+ ++D E+QYE+L EE+ LK Sbjct: 230 DNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALK 289 Query: 226 KNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKS 285 KNH+EEM L G+VNVE+N APG DL LN+MR EYE L +NRKD E + + Sbjct: 290 KNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQI 349 Query: 286 ASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQL 345 ++ ++S + ++T++R +Q LEI+LQS ++ K +LE SL +T++ YC QL Sbjct: 350 TQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQL 409 Query: 346 AQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSK 405 IQ QI LE Q+ VR E E Q EY LL +K+ LEKEIETY L++G G +S Sbjct: 410 QMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG-GQEDFESS 468 Query: 406 GFG 408 G G Sbjct: 469 GAG 471 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 10/77 (12%) Query: 16 SGAGSVRPLNGG-AGFAGSSACGGSVAGSEFSCALGGGLGSV--PGGSHAGGALGNAACI 72 SG G GG +G +G + GGS +G GGG GS GGSH GG+ Sbjct: 538 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGS------- 590 Query: 73 GFAGSEGGLLSGNEKVT 89 GF G GG G E+ + Sbjct: 591 GFGGESGGSYGGGEEAS 607 Score = 39.7 bits (91), Expect = 0.006 Identities = 28/69 (40%), Positives = 32/69 (46%), Gaps = 8/69 (11%) Query: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCA-LGGGLGSVPGGSHAGGALGNAACIGFA 75 G GS GG+G G S GGS G S GGG G GG H+GG+ G G + Sbjct: 499 GGGSGGGYGGGSGSRGGS--GGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGG-----GHS 551 Query: 76 GSEGGLLSG 84 G GG G Sbjct: 552 GGSGGNYGG 560 Score = 38.9 bits (89), Expect = 0.010 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 3/64 (4%) Query: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76 G GS G + G S GG +G + GGG GG H+GG+ GN G +G Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGG-SGGGYGGGSGGGHSGGSGGGHSGGSGGNYG--GGSG 563 Query: 77 SEGG 80 S GG Sbjct: 564 SGGG 567 Score = 36.6 bits (83), Expect = 0.050 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 3/63 (4%) Query: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76 G GS G G+ G S GS GS S G G G GGS+ GG + + G+ G Sbjct: 559 GGGSGSGGGSGGGYGGGS---GSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGG 615 Query: 77 SEG 79 G Sbjct: 616 GSG 618 Score = 36.2 bits (82), Expect = 0.065 Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 10/78 (12%) Query: 16 SGAGSVRPLNGGAGFAGS------SACGGSVAGSEFSCALGGGLGS--VPGGSHAGGA-L 66 SGAG + L G G GS GGS G GGG GS GGS+ GG+ Sbjct: 468 SGAGKIG-LGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS 526 Query: 67 GNAACIGFAGSEGGLLSG 84 G + G+ G GG SG Sbjct: 527 GGGSGGGYGGGSGGGHSG 544 Score = 34.3 bits (77), Expect = 0.25 Identities = 25/69 (36%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFA 75 S GS GG G GS GS S G G G GG + GG+ G G + Sbjct: 489 SRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGG-----GHS 543 Query: 76 GSEGGLLSG 84 G GG SG Sbjct: 544 GGSGGGHSG 552 Score = 33.5 bits (75), Expect = 0.42 Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 16 SGAGSVRPLNGGAGFAGSSACG-GSVAGSEFSCALGGGLGSVPGGSHAGGA-LGNAACIG 73 S GS GG+G G S G G +G S GGG GG++ GG+ G + G Sbjct: 512 SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG 571 Query: 74 FAGSEG 79 + G G Sbjct: 572 YGGGSG 577 Score = 32.7 bits (73), Expect = 0.72 Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60 S GS GG+GF G S GGS G E + GGG G G S Sbjct: 578 SRGGSGGSHGGGSGFGGES--GGSYGGGEEASGSGGGYGGGSGKS 620 Score = 31.6 bits (70), Expect = 1.6 Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 4/75 (5%) Query: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEF--SCALGGGLGSVPGGSHAGGALGNAACIG- 73 G+G G + G S GG G S + GG GS GGS GG G + G Sbjct: 545 GSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGE 604 Query: 74 -FAGSEGGLLSGNEK 87 +GS GG G+ K Sbjct: 605 EASGSGGGYGGGSGK 619 Score = 31.2 bits (69), Expect = 2.1 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 25 NGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGGLLSG 84 + GAG G GGS GS + GG GS GG GG G + G +G G SG Sbjct: 467 SSGAGKIGLGGRGGS-GGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG 525 Query: 85 N 85 + Sbjct: 526 S 526 Score = 30.8 bits (68), Expect = 2.7 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 4/54 (7%) Query: 16 SGAGSVRPLNGGAGF---AGSSACGGSVAGSEFSCALGGG-LGSVPGGSHAGGA 65 SG GS GG+G +G S GGS G E + GGG S GG + GG+ Sbjct: 564 SGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGS 617 >gi|94538345 keratin 35 [Homo sapiens] Length = 455 Score = 320 bits (821), Expect = 1e-87 Identities = 182/409 (44%), Positives = 254/409 (62%), Gaps = 33/409 (8%) Query: 13 CLRSG--AGSVRPLNGGAGFA-------GSSACG----GSVAGSEFSCALGGGLGS---- 55 CL++G +GS++ G +G + SS+C VA S +C++G G S Sbjct: 5 CLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRAT 64 Query: 56 -------VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALE 108 +P G A G G G+L+GNEK TMQ+LNDRLA YL+ VR LE Sbjct: 65 SCLPALCLPAGGFATSYSGGGGWFG-----EGILTGNEKETMQSLNDRLAGYLEKVRQLE 119 Query: 109 EANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNA 168 + NA LE +I+ W E+ P C DY Y TIE+L+ K + S NA ++++IDNA Sbjct: 120 QENASLESRIREWCEQQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNA 175 Query: 169 RLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNH 228 +LAADDFR KYE E++L Q VE+DINGLRR+LD+LTLC++D E Q ESL EE+ LKKNH Sbjct: 176 KLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNH 235 Query: 229 EEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASL 288 EEE+ +L+C G +NVE++AAP VDL +L MR +YE L E NR+DAE W + +S L Sbjct: 236 EEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEEL 295 Query: 289 QQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQI 348 QQ+ S ++++ E+RRT+ LEI+LQ+ + + +LE +L ETE+ Y +QLAQ+ Sbjct: 296 NQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQM 355 Query: 349 QAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD 397 Q I +E QL ++R + E Q EY+ LLDV+ LE EI TY L++ + Sbjct: 356 QCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESE 404 >gi|27894337 keratin 20 [Homo sapiens] Length = 424 Score = 320 bits (819), Expect = 2e-87 Identities = 181/403 (44%), Positives = 264/403 (65%), Gaps = 15/403 (3%) Query: 51 GGLGSVPGGSHAGGA-LGNAACIGFAGSE----GGLLSGNEKVTMQNLNDRLASYLDNVR 105 G SV GG+ G + N+ GS+ G L GNEK+ MQNLNDRLASYL+ VR Sbjct: 30 GTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVR 89 Query: 106 ALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQI 165 LE++N++LE +IK WYE P + R DYS Y+ IE+L+++I + NA +LQI Sbjct: 90 TLEQSNSKLEVQIKQWYETNAPRAGR----DYSAYYRQIEELRSQIKDAQLQNARCVLQI 145 Query: 166 DNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLK 225 DNA+LAA+DFRLKYE E + VEAD+ GL +V D+LTL +TD E+Q E L++++ LK Sbjct: 146 DNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLK 205 Query: 226 KNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKS 285 K H+EE+ L G VNVE++AAPG++L V++N MR +YE +A++N ++A+ F ++ Sbjct: 206 KEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQT 265 Query: 286 ASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQL 345 A LQQQ++ ++ QLTE+RRT Q+LEI+LQS ++ K SLE +L ET++ Y +QL Sbjct: 266 AVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQL 325 Query: 346 AQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSK 405 A +Q+ + +LE QL Q+R+ E Q EY LLD+K LE+EI TY RL++G+ ++ + Sbjct: 326 ANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQ 385 Query: 406 GFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVLSSRIHSIEE 448 +D+ KT +KTVV+E+ GKV+SS + +EE Sbjct: 386 -----LSTLEERDIKKTRKIKTVVQEVVD-GKVVSSEVKEVEE 422 >gi|116488398 keratin 32 [Homo sapiens] Length = 448 Score = 303 bits (777), Expect = 2e-82 Identities = 166/345 (48%), Positives = 224/345 (64%), Gaps = 16/345 (4%) Query: 70 ACIGFAGSEG-------GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWY 122 A G +GS G G +GNEK TMQ LNDRLASYL VR LE+ NAELE +I Sbjct: 73 AASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRI---- 128 Query: 123 EKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENE 182 ++ + DY + TIE+L+ KI+ + NA +++ IDNA+LAADDFR KYE E Sbjct: 129 QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAE 188 Query: 183 LTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGN 242 L + Q VEADINGLRR+LD+LTLC+ D E Q ESL EE+ LKKNHEEE+ +L+C G Sbjct: 189 LAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDR 248 Query: 243 VNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFA 302 +N+E++AAP VDL +L MR +YEA+ E NR+D E WFN + L QQ++ S Sbjct: 249 LNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNY 308 Query: 303 RSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQV 362 +S + ++RRT+ TLEI+LQ+ + + SLE +LTE+E+ Y +QLAQ+Q I +E QL ++ Sbjct: 309 QSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEI 368 Query: 363 RTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCS 402 R + E Q EY+ LLDV+ LE EI TY L++ + N CS Sbjct: 369 RADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCS 413 >gi|14917117 keratin 33A [Homo sapiens] Length = 404 Score = 300 bits (768), Expect = 2e-81 Identities = 162/338 (47%), Positives = 224/338 (66%), Gaps = 15/338 (4%) Query: 80 GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139 G +G+EK TMQ LNDRLASYL+ VR LE NAELE I+ ++ P C Y Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCAS----YQS 105 Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199 Y TIE+L+ KI+ S + NA +++QIDNA+LA+DDFR KYE EL+L Q VE+DINGLRR+ Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165 Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259 LDELTLCR+D E Q ESL EE+ LK+NHE+E+ L+C G +NVE++AAP VDL +L Sbjct: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225 Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319 N R++YEAL E NR++ E WF ++ L +Q+ S ++++ E+RRT+ LEI+ Sbjct: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285 Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379 LQ+ + SLE +LTE+E+ Y +QL+Q+Q I +E QL ++R++ E Q EY+ LLDV Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345 Query: 380 KVHLEKEIETYCRLIDGDG-----------NSCSKSKG 406 + LE EI TY L++ + N+C KS G Sbjct: 346 RARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTG 383 >gi|14917115 keratin 31 [Homo sapiens] Length = 416 Score = 297 bits (760), Expect = 2e-80 Identities = 160/338 (47%), Positives = 224/338 (66%), Gaps = 15/338 (4%) Query: 80 GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139 G +G+EK TMQ LNDRLASYL+ VR LE NAELE I+ ++ P C Y Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105 Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199 Y TIE+L+ KI+ + + NA +++QIDNA+LAADDFR KY+ EL+L Q VE+DINGLRR+ Sbjct: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165 Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259 LDELTLC++D E Q ESL EE+ LK NHE+E+ L+C G +NVE++AAP VDL +L Sbjct: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225 Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319 N R++YEAL E NR++ E WF ++ L +Q+ S ++++ E+RRT+ LEI+ Sbjct: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285 Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379 LQ+ + SLE +LTE+E+ Y +QL+Q+Q+ I +E QL ++R++ E Q EY+ LLDV Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345 Query: 380 KVHLEKEIETYCRLIDGDG-----------NSCSKSKG 406 + LE EI TY L++ + N+CSK G Sbjct: 346 RARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIG 383 >gi|10337581 type I hair keratin 3B [Homo sapiens] Length = 404 Score = 294 bits (752), Expect = 1e-79 Identities = 155/318 (48%), Positives = 217/318 (68%), Gaps = 4/318 (1%) Query: 80 GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139 G +G+EK TMQ LNDRLASYL+ VR LE NAELE I+ ++ P C Y Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105 Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199 Y TIE+L+ KI+ S + NA +++QIDNA+LAADDFR KY+ E +L Q VE+DIN LRR+ Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRI 165 Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259 LDELTLCR+D E Q ESL EE+ LK+NHE+E+ L+C G +NVE++AAP VDL +L Sbjct: 166 LDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVL 225 Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319 N R +YEAL E NR++ E WF ++ L +Q+ S ++++ E+RRT+ LEI+ Sbjct: 226 NETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285 Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379 LQ+ ++SLE +LTE+E+ Y +QL+Q+Q+ I +E QL ++R++ E Q EY+ LLDV Sbjct: 286 LQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345 Query: 380 KVHLEKEIETYCRLIDGD 397 + LE EI TY L++ + Sbjct: 346 RARLECEINTYRSLLESE 363 >gi|27894339 keratin 23 [Homo sapiens] Length = 422 Score = 286 bits (732), Expect = 3e-77 Identities = 168/444 (37%), Positives = 253/444 (56%), Gaps = 30/444 (6%) Query: 9 SRHVCLRSGAGSVRPLNGGAG----FAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGG 64 S H ++ + S GG G F + G G+ S + PGGS Sbjct: 3 SGHSFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWG-- 60 Query: 65 ALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEK 124 +G LL GN K TMQNLNDRLASYL+ VRALEEAN +LE +I W+++ Sbjct: 61 ----------SGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQ 110 Query: 125 YGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELT 184 PGS + DYS+Y I L+ +I+ TNA +IL IDNAR+A DDF LKYENE + Sbjct: 111 RDPGSKK----DYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHS 166 Query: 185 LHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVN 244 +++E ++ GLRR LD LT+ TD E + E + +E+ +KK+HE+EM+ + NVN Sbjct: 167 FKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVN 226 Query: 245 VEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARS 304 V+++ P DL +L +MR EYE + ++ +D + W+ E+SA++ Q+ + + + + Sbjct: 227 VKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPATVQS-RQG 285 Query: 305 QLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRT 364 + E++RT Q LEI LQ+ +TK +LE L+ET+S Y +L +Q I EE+L Q+R Sbjct: 286 DIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRH 345 Query: 365 ETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTTL 424 E E Q EY+ LL +K HLEKEI TY RL++G+ G+ SS +S T Sbjct: 346 ELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESE--------GTREESKSSMKVSATPK 397 Query: 425 VKTVVEELDQRGKVLSSRIHSIEE 448 +K + +E G+++ +++ I++ Sbjct: 398 IKAITQE-TINGRLVLCQVNEIQK 420 >gi|40354195 keratin 18 [Homo sapiens] Length = 430 Score = 284 bits (727), Expect = 1e-76 Identities = 178/421 (42%), Positives = 251/421 (59%), Gaps = 29/421 (6%) Query: 22 RPLNGGAG-FAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGG 80 RP++ A +AG+ G ++ S S + GG+GS G L G AG GG Sbjct: 27 RPVSSAASVYAGAGGSGSRISVSR-STSFRGGMGS--------GGLATGIAGGLAGM-GG 76 Query: 81 LLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRY 140 + NEK TMQ+LNDRLASYLD VR+LE N LE KI+ EK GP D+S Y Sbjct: 77 IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-----RDWSHY 129 Query: 141 HLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVL 200 IEDL+ +I ++T NA ++LQIDNARLAADDFR+KYE EL + Q+VE DI+GLR+V+ Sbjct: 130 FKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVI 189 Query: 201 DELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQC-AAGGNVNVEMNAAPGVDLAVLL 259 D+ + R E + E+L EE+ ++KKNHEEE+K LQ A + VE++A DLA ++ Sbjct: 190 DDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIM 249 Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319 ++RA+Y+ LA +NR++ + +++++ ++ S A + LTE+RRT+Q+LEI Sbjct: 250 ADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEID 309 Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379 L S+ K SLE SL E E+ Y Q+ Q+ + LE +L Q R E + Q EYE LL++ Sbjct: 310 LDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNI 369 Query: 380 KVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVL 439 KV LE EI TY RL++ DG + S NS + + KTT + V GKV+ Sbjct: 370 KVKLEAEIATYRRLLE-DGEDFNLGDALDS---SNSMQTIQKTTTRRIV------DGKVV 419 Query: 440 S 440 S Sbjct: 420 S 420 >gi|4557888 keratin 18 [Homo sapiens] Length = 430 Score = 284 bits (727), Expect = 1e-76 Identities = 178/421 (42%), Positives = 251/421 (59%), Gaps = 29/421 (6%) Query: 22 RPLNGGAG-FAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGG 80 RP++ A +AG+ G ++ S S + GG+GS G L G AG GG Sbjct: 27 RPVSSAASVYAGAGGSGSRISVSR-STSFRGGMGS--------GGLATGIAGGLAGM-GG 76 Query: 81 LLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRY 140 + NEK TMQ+LNDRLASYLD VR+LE N LE KI+ EK GP D+S Y Sbjct: 77 IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-----RDWSHY 129 Query: 141 HLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVL 200 IEDL+ +I ++T NA ++LQIDNARLAADDFR+KYE EL + Q+VE DI+GLR+V+ Sbjct: 130 FKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVI 189 Query: 201 DELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQC-AAGGNVNVEMNAAPGVDLAVLL 259 D+ + R E + E+L EE+ ++KKNHEEE+K LQ A + VE++A DLA ++ Sbjct: 190 DDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIM 249 Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319 ++RA+Y+ LA +NR++ + +++++ ++ S A + LTE+RRT+Q+LEI Sbjct: 250 ADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEID 309 Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379 L S+ K SLE SL E E+ Y Q+ Q+ + LE +L Q R E + Q EYE LL++ Sbjct: 310 LDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNI 369 Query: 380 KVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVL 439 KV LE EI TY RL++ DG + S NS + + KTT + V GKV+ Sbjct: 370 KVKLEAEIATYRRLLE-DGEDFNLGDALDS---SNSMQTIQKTTTRRIV------DGKVV 419 Query: 440 S 440 S Sbjct: 420 S 420 >gi|14917119 keratin 34 [Homo sapiens] Length = 436 Score = 283 bits (723), Expect = 3e-76 Identities = 156/345 (45%), Positives = 223/345 (64%), Gaps = 11/345 (3%) Query: 80 GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139 G +G+EK TMQ LNDRLASYL+ VR LE NAELE+ I+ ++ P C Y Sbjct: 92 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPS----YQS 147 Query: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199 Y TIE+L+ KI+ + NA +++ IDNA+LA+DDFR KY+ E +L VE+DIN +RR+ Sbjct: 148 YFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRI 207 Query: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259 LDELTLC++D E Q ESL EE+ LKKNHEEE+ L+ G +NVE++ AP VDL +L Sbjct: 208 LDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVL 267 Query: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319 N R++YEAL E NR++ E WF ++ L +Q+ S ++++ E+RRT+ LEI+ Sbjct: 268 NETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIE 327 Query: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379 LQ+ + SLE +LTE+E++Y +QL+Q+Q+ I +E QL ++R + E Q EY+ LLDV Sbjct: 328 LQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDV 387 Query: 380 KVHLEKEIETYCRLIDGDG-----NSCSKSKGFGS--GSPGNSSK 417 + LE EI TY L++ + N C+ + G+ G G S K Sbjct: 388 RARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPCGTSQK 432 >gi|125490370 type I hair keratin KA36 [Homo sapiens] Length = 431 Score = 278 bits (712), Expect = 6e-75 Identities = 154/339 (45%), Positives = 217/339 (64%), Gaps = 8/339 (2%) Query: 68 NAACI--GFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKY 125 N+ C+ A E G+ + NEK TMQ LNDRLASYL+ VR+LEE NAELE +I+ E+ Sbjct: 69 NSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQD 128 Query: 126 GPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTL 185 P C DY RY TIEDL+ KI+ + N+ + +Q+DN +LA DDF+ KYE+EL+L Sbjct: 129 IPMVCP----DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSL 184 Query: 186 HQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNV 245 Q +EADI+ L +L+ELTLC++D E ESL E++ LKKNHEEE+ L+ G ++V Sbjct: 185 RQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSV 244 Query: 246 EMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQ 305 E++ AP +DL +L+ MR + E + NR++AE W ++ L QQ + + + Sbjct: 245 ELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQME 304 Query: 306 LTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTE 365 + E++RT LEI+LQ+ + SLEC++ ETE+ Y +QLAQIQ I LE QL ++R + Sbjct: 305 ILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCD 364 Query: 366 TEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGN--SCS 402 E Q EY+ LLDVK LE EI TY L+D + + SCS Sbjct: 365 LERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCS 403 >gi|148277620 type I hair keratin KA35 [Homo sapiens] Length = 491 Score = 271 bits (694), Expect = 7e-73 Identities = 147/314 (46%), Positives = 199/314 (63%), Gaps = 4/314 (1%) Query: 82 LSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYH 141 ++ NEK TMQ LN+RLA+YL VR LE NAELE KI+ K P C DY Y+ Sbjct: 92 INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147 Query: 142 LTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLD 201 TIE+L+ KI+ + N+ ++ QIDN +L ADD R KYE E++L Q VE+D NGL+++L+ Sbjct: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207 Query: 202 ELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNN 261 LTL + D E Q +SL EE+ LK NH+EE+ +LQC G +++E+ AAP DL +L Sbjct: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267 Query: 262 MRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQ 321 MR +YE + E NRKD E WFN + L QQ+ S + ++ E+RR++ TLE++LQ Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327 Query: 322 SLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKV 381 + + S EC LTETE+ Y L QIQ+ I LE QL ++R E Q EYE LLDVK Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387 Query: 382 HLEKEIETYCRLID 395 LE EI TY L++ Sbjct: 388 RLECEITTYRSLLE 401 >gi|55770882 keratin 37 [Homo sapiens] Length = 449 Score = 265 bits (676), Expect = 9e-71 Identities = 152/352 (43%), Positives = 209/352 (59%), Gaps = 14/352 (3%) Query: 56 VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELE 115 +PG H G +G G L+G+EK TM+ LNDRLA+YL+ VR LE+ NAELE Sbjct: 79 LPGTCHIPGNIGICGAYG-----KNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELE 133 Query: 116 RKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDF 175 + + + C DY Y TIE+L+ KI+ S NA +I+QIDNA+LAADDF Sbjct: 134 TTLLERSKCHESTVCP----DYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDF 189 Query: 176 RLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKAL 235 R+K E+E +LHQ VEAD G +++LD+ TL + D E Q ESL EE LK NHE+E+K L Sbjct: 190 RIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKIL 249 Query: 236 QCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHD 295 + G +E++ P +DL +L MRA+YEA+ E N +D E WF +S + Q Sbjct: 250 RSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSC 309 Query: 296 SGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGAL 355 S +S++ E+R T+ LE++ Q+ K L+ SL E E Y T+LAQ+Q+ I L Sbjct: 310 SEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNL 369 Query: 356 EEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCS 402 EEQL ++R + E Q EY+ LLDVK LE EI TY L++ + N CS Sbjct: 370 EEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCS 421 >gi|15431318 keratin 38 [Homo sapiens] Length = 456 Score = 263 bits (671), Expect = 3e-70 Identities = 152/354 (42%), Positives = 211/354 (59%), Gaps = 14/354 (3%) Query: 56 VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELE 115 +PG H G +G G L+G+EK TMQ LNDRLA+YL+ VR LE+ NAELE Sbjct: 79 LPGTCHIPGNIGICGAYG-----ENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELE 133 Query: 116 RKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDF 175 + + + C DY Y TIE+L+ KI+ S NA +I+QIDNA+LAADDF Sbjct: 134 ATLLERSKCHESTVCP----DYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDF 189 Query: 176 RLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKAL 235 R+K E+E +L Q VEAD G +++LD+ TL + D E Q ESL EE LK NHE+E+K L Sbjct: 190 RIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKIL 249 Query: 236 QCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHD 295 + G + +E++ P +DL +L MRA+YEA+ E NR+D E WF +S + Q Sbjct: 250 RSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSC 309 Query: 296 SGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGAL 355 S +S++ E+R T+ LE++ Q+ K L+ SL E E + T+LAQ+Q+ I + Sbjct: 310 SEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNV 369 Query: 356 EEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCSKS 404 EEQL ++R + E Q EY+ LLDVK LE EI TY L++ + N CS S Sbjct: 370 EEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTS 423 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.359 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,089,672 Number of Sequences: 37866 Number of extensions: 788361 Number of successful extensions: 5961 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 177 Number of HSP's successfully gapped in prelim test: 318 Number of HSP's that attempted gapping in prelim test: 3780 Number of HSP's gapped (non-prelim): 1533 length of query: 464 length of database: 18,247,518 effective HSP length: 106 effective length of query: 358 effective length of database: 14,233,722 effective search space: 5095672476 effective search space used: 5095672476 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.