Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 22027646
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22027646 angiomotin like 1 [Homo sapiens]
(956 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22027646 angiomotin like 1 [Homo sapiens] 1907 0.0
gi|166064029 angiomotin isoform 1 [Homo sapiens] 755 0.0
gi|19111150 angiomotin isoform 2 [Homo sapiens] 557 e-158
gi|32484977 angiomotin like 2 [Homo sapiens] 534 e-151
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 66 2e-10
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 65 4e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 1e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 2e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 62 3e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 3e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 3e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 61 6e-09
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 61 6e-09
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 60 1e-08
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 60 1e-08
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 60 1e-08
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 60 1e-08
gi|34577114 cytomatrix protein p110 [Homo sapiens] 59 3e-08
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 58 4e-08
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 58 4e-08
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 58 4e-08
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 58 4e-08
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 58 5e-08
gi|71061468 centromere protein E [Homo sapiens] 57 6e-08
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 57 6e-08
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 57 8e-08
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 57 8e-08
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 57 8e-08
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 57 8e-08
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 57 8e-08
>gi|22027646 angiomotin like 1 [Homo sapiens]
Length = 956
Score = 1907 bits (4939), Expect = 0.0
Identities = 956/956 (100%), Positives = 956/956 (100%)
Query: 1 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS 60
MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS
Sbjct: 1 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS 60
Query: 61 SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA 120
SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
Sbjct: 61 SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA 120
Query: 121 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ 180
IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
Sbjct: 121 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ 180
Query: 181 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN 240
PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
Sbjct: 181 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN 240
Query: 241 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA 300
SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
Sbjct: 241 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA 300
Query: 301 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA 360
GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
Sbjct: 301 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA 360
Query: 361 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP 420
VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
Sbjct: 361 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP 420
Query: 421 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS 480
PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
Sbjct: 421 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS 480
Query: 481 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK 540
EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
Sbjct: 481 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK 540
Query: 541 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR 600
AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
Sbjct: 541 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR 600
Query: 601 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE 660
EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
Sbjct: 601 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE 660
Query: 661 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS 720
YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
Sbjct: 661 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS 720
Query: 721 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA 780
RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
Sbjct: 721 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA 780
Query: 781 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH 840
GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
Sbjct: 781 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH 840
Query: 841 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS 900
ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
Sbjct: 841 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS 900
Query: 901 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI 956
TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
Sbjct: 901 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI 956
>gi|166064029 angiomotin isoform 1 [Homo sapiens]
Length = 1084
Score = 755 bits (1950), Expect = 0.0
Identities = 450/888 (50%), Positives = 577/888 (64%), Gaps = 107/888 (12%)
Query: 87 MRGSEDAAAG--TVLQRLIQEQLRYGTPTENMNLLAIQHQATGSAGPAHPT---NNFSST 141
MR SE+ +G TVLQRL+QEQLRYG P+EN +LLAI QATG+ GP P+ N +
Sbjct: 1 MRNSEEQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGN-GPPFPSGSGNPGPQS 59
Query: 142 ENLTQED--PQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQ 199
+ L+ +D Q+V +ARQEPQGQE Q +N +MEKQ+ + QNNEELPTYEEAK QSQ
Sbjct: 60 DVLSPQDHHQQLVAHAARQEPQGQEIQSENLIMEKQL--SPRMQNNEELPTYEEAKVQSQ 117
Query: 200 FFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVR 259
+FRGQQ +VG +Y+ G T+QK RTEGRP+V R N G+ H+DE L++LKQGHVR
Sbjct: 118 YFRGQQH-----ASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVR 172
Query: 260 SLSERIMQLSLERNGAKQHLPGSG----------------NGKGFKVGGGPSPAQPAGKV 303
SLSER+MQ+SL +G K H P + + F GP P Q + K
Sbjct: 173 SLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKG 232
Query: 304 LDPRGPPPEYPFKTKQMMSPVSKTQ-------EHGLFYGDQHPGMLHEMVKP--YPAPQP 354
++ RGPPPEYPFK S V K Q EH L + G L P Y A +P
Sbjct: 233 MEHRGPPPEYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARP 292
Query: 355 ---VRTDVAVLRYQP-PPEYGVTS---------------RPCQLPFPSTMQQHS---PMS 392
+ ++ QP P +TS P + P HS P
Sbjct: 293 AQDISLPLSARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRP 352
Query: 393 SQ----TSSASGPLHSVSLP-----------------------------LPLPMALGAPQ 419
Q + G + +S P P P+
Sbjct: 353 QQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPR 412
Query: 420 PPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRI 479
P+++ Q + D FAIV RAQQMVEIL++ENR L QEL+G Y+ +L K E E+QR+
Sbjct: 413 AQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRV 472
Query: 480 SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED 539
SEAYE+LVKS++KRE+L+KAMRNKLEGEIRR+HDFNRDLR+RLETAN+QL+ +EYEG ED
Sbjct: 473 SEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSED 532
Query: 540 -KAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEE 598
+ ++NKE +EKEKLE ELA R+ +ED RRHIEI DQALSNAQA+V+KLEEE
Sbjct: 533 TRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEE 592
Query: 599 LREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANM 658
L++KQ YV+KVEK+QQAL QLQ+ACEKREQ+E RLRT LEREL++LR QQ+ GN QP N+
Sbjct: 593 LKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNV 652
Query: 659 PEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIIN 718
EYNA AL+EL+REKEERILALEADMTKWEQKYLEE+ +RHFA++AAAT AA+RDTT+I+
Sbjct: 653 SEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVIS 712
Query: 719 HSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRK 778
HS N SY +++LEA I +EEEE++ AN+RC DME IK LHA+IIEKDAMIKVLQQRSRK
Sbjct: 713 HSPNTSY-DTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRK 771
Query: 779 DAGKTDS-SSLRPARSVPSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKE 836
+ KT+ S +RPA+S+ SI+ A +G S ++LT S + EEK+++K+WKGS+G+LLG +
Sbjct: 772 EPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGD 831
Query: 837 HHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAE 884
+ A +P P S + +T SAH+KTGS+D STQT++ E
Sbjct: 832 YR----AEYVPSTP----SPVPPSTPLLSAHSKTGSRDCSTQTERGTE 871
>gi|19111150 angiomotin isoform 2 [Homo sapiens]
Length = 675
Score = 557 bits (1435), Expect = e-158
Identities = 292/470 (62%), Positives = 374/470 (79%), Gaps = 12/470 (2%)
Query: 418 PQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQ 477
P+ P+++ Q + D FAIV RAQQMVEIL++ENR L QEL+G Y+ +L K E E+Q
Sbjct: 2 PRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQ 61
Query: 478 RISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGH 537
R+SEAYE+LVKS++KRE+L+KAMRNKLEGEIRR+HDFNRDLR+RLETAN+QL+ +EYEG
Sbjct: 62 RVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGS 121
Query: 538 ED-KAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLE 596
ED + ++NKE +EKEKLE ELA R+ +ED RRHIEI DQALSNAQA+V+KLE
Sbjct: 122 EDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLE 181
Query: 597 EELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPA 656
EEL++KQ YV+KVEK+QQAL QLQ+ACEKREQ+E RLRT LEREL++LR QQ+ GN QP
Sbjct: 182 EELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPT 241
Query: 657 NMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI 716
N+ EYNA AL+EL+REKEERILALEADMTKWEQKYLEE+ +RHFA++AAAT AA+RDTT+
Sbjct: 242 NVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTV 301
Query: 717 INHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRS 776
I+HS N SY +++LEA I +EEEE++ AN+RC DME IK LHA+IIEKDAMIKVLQQRS
Sbjct: 302 ISHSPNTSY-DTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRS 360
Query: 777 RKDAGKTDS-SSLRPARSVPSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLG 834
RK+ KT+ S +RPA+S+ SI+ A +G S ++LT S + EEK+++K+WKGS+G+LLG
Sbjct: 361 RKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLG 420
Query: 835 KEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAE 884
++ A +P P S + +T SAH+KTGS+D STQT++ E
Sbjct: 421 GDYR----AEYVPSTP----SPVPPSTPLLSAHSKTGSRDCSTQTERGTE 462
>gi|32484977 angiomotin like 2 [Homo sapiens]
Length = 780
Score = 534 bits (1375), Expect = e-151
Identities = 356/810 (43%), Positives = 463/810 (57%), Gaps = 94/810 (11%)
Query: 87 MRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLAIQHQAT-GSAGPAHPTNNFSSTENLT 145
MR ED++ GTVL RLIQEQLRYG TE LLAIQ QA G AG + +S E L
Sbjct: 1 MRTLEDSS-GTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGTGGTGSPQASLEILA 59
Query: 146 QEDPQMVYQSARQEPQGQEHQV-DNTVMEKQVRSTQPQQNN-EELPTYEEAKAQSQFFRG 203
ED Q++ Q+ RQEPQGQEHQ +N + E + PQ + EELPTYEEAKA SQ++
Sbjct: 60 PEDSQVLQQATRQEPQGQEHQGGENHLAENTLYRLCPQPSKGEELPTYEEAKAHSQYYAA 119
Query: 204 QQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSE 263
QQ G H AG + A G +DEAL+EL+ GHVRSLSE
Sbjct: 120 QQA-----GTRPH----AGDRDPRG----------APGGSRRQDEALRELRHGHVRSLSE 160
Query: 264 RIMQLSLERNGAK--QHLPGSGNGKGF-KVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQM 320
R++QLSLERNGA+ H+ S + + GP P + + RGPPP+YP
Sbjct: 161 RLLQLSLERNGARAPSHMSSSHSFPQLARNQQGPPLRGPPAEGPESRGPPPQYP------ 214
Query: 321 MSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLP 380
H + + + + +P +V +L+ Q PP + + Q
Sbjct: 215 ---------HVVLAHETTTAVTDPRYRARGSPHFQHAEVRILQAQVPPVF--LQQQQQYQ 263
Query: 381 FPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVER 440
+ Q+H P + GPL S+S P P A + S G A +E
Sbjct: 264 YLQQSQEHPPPPHPAALGHGPLSSLSPP-------AVEGPVSAQASSATSGSAHLAQMEA 316
Query: 441 AQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAM 500
+ L +N L +EL+ + A ++ K E E+QR+SEA+ESL ++++KRE+L+K M
Sbjct: 317 VLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTM 376
Query: 501 RNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYE---GHEDKAAEGHYASQNKEFLKEK 557
RNK++ E+RRL DFNRDLR+RLE+ANR+L+S+ E G +D A+ +Q+ E +E+
Sbjct: 377 RNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAK--LLAQSYEQQQEQ 434
Query: 558 EKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALT 617
EKLE E+A +R A ED RR E+L+QAL NAQ R + EEELR+KQAYVEKVE+LQQAL
Sbjct: 435 EKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALG 494
Query: 618 QLQSACEKREQMERRLRTWLERELDALRTQQKH-----GNGQPANMPEYNAPALLELVRE 672
QLQ+ACEKREQ+E RLRT LE+EL ALR QQ+ G+ PE +A L E +RE
Sbjct: 495 QLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLRE 554
Query: 673 KEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEA 732
KEE+ILALEADMTKWEQKYLEE +R FAM+AAATAAA+RDTT+I HS S S
Sbjct: 555 KEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSF--- 611
Query: 733 HIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPAR 792
E ++ R Q+ME +K LHA+I+EKDA+IKVLQQRSR+D GK SLRPA+
Sbjct: 612 -----NEGLLTGGHRHQEMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGSLRPAK 666
Query: 793 SVPSI--AAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPP 850
SVPS+ AAA GT W+G L + A AP
Sbjct: 667 SVPSVFAAAAAGTQG-------------------WQG-----LSSSERQTADAPARLTTA 702
Query: 851 TSALSSIASTTAASSAHAKTGSKDSSTQTD 880
A + TA +AHAK GS+D STQT+
Sbjct: 703 DRAPTEEPVVTAPPAAHAKHGSRDGSTQTE 732
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 65.9 bits (159), Expect = 2e-10
Identities = 88/414 (21%), Positives = 171/414 (41%), Gaps = 75/414 (18%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNA-----------------DKLHKFEKELQRIS 480
V + ++E +EN +L +E+ ++NA K+ E+ L+ +
Sbjct: 343 VHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLE 402
Query: 481 EAYESLVK----STTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEG 536
E + L ST +RE K M E+ R H ++ +++++E +LSS+E +
Sbjct: 403 EEIQMLKSNGALSTEEREEEMKQM------EVYRSH--SKFMKNKVEQLKEELSSKEAQW 454
Query: 537 HEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASE-------DHRRHIEILDQALSNAQ 589
E K ++ + +E + + EL A++T E D ++HIE+L ++L+ +
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKE 514
Query: 590 ARVIKLEEELREKQAYVEKVE-KLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQ 648
R L+ E+ + +E+ E L + Q+Q E++ + L+ LD
Sbjct: 515 QRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD-LKDMLDV----- 568
Query: 649 KHGNGQPANMPEYNAPALLELVREKE-------ERILALEADMTKWEQKYLEESTIRHFA 701
+ N+ + L E +R+KE ER+ +L+AD T + A
Sbjct: 569 ---KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDT-----------A 614
Query: 702 MNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAK 761
+ A AE++ TI E +++EE+ + +D++ + L
Sbjct: 615 LTTLEEALAEKERTIERLKEQRDRDER-------EKQEEIDNYKKDLKDLKEKVSLLQGD 667
Query: 762 IIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQL 815
+ EK+A + L++ A SS L+ + ++ A + SQL
Sbjct: 668 LSEKEASLLDLKEH----ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQL 717
Score = 41.2 bits (95), Expect = 0.005
Identities = 42/186 (22%), Positives = 87/186 (46%), Gaps = 8/186 (4%)
Query: 466 ADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETA 525
A+ HK + E ++ ++ +++ +RE +L+ +R+ D +L + L +
Sbjct: 794 ANLKHKEQVEKKKSAQ----MLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRES 849
Query: 526 NRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQAL 585
+ + RE ++++A + Q +E L EK++ EL +++ ++ + + L
Sbjct: 850 VQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHL 909
Query: 586 SNAQARVIK-LEEELREKQ-AYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDA 643
+N +A K LEE L KQ A + + + + L+ + K++ E L+RE D
Sbjct: 910 TNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAA--LKREKDR 967
Query: 644 LRTQQK 649
L Q K
Sbjct: 968 LVQQLK 973
Score = 40.4 bits (93), Expect = 0.008
Identities = 63/368 (17%), Positives = 135/368 (36%), Gaps = 41/368 (11%)
Query: 422 PAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISE 481
P + L D + + ++ ++ EEN+ + +Q D RI
Sbjct: 192 PELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDEL-----------RIQR 240
Query: 482 AYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKA 541
L + + + + + E +RLH + L + L E K
Sbjct: 241 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ 300
Query: 542 AEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRR---------HIEILDQALSNAQARV 592
++++ K E L+ + + + EDH R H+ L+ L +
Sbjct: 301 TLN---ARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKEN 357
Query: 593 IKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD------ALRT 646
L EE+ + K + T ++ K MER LR LE E+ AL T
Sbjct: 358 SMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRD-LEEEIQMLKSNGALST 416
Query: 647 QQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAA 706
+++ + + ++ + V + +E + + EA +WE+ + + ++ +
Sbjct: 417 EEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEA---QWEELKKKAAGLQ-AEIGQVK 472
Query: 707 TAAAERDTTIIN-----HSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAK 761
+ +DT ++ + + +S + HI +E + +R ++ + L +
Sbjct: 473 QELSRKDTELLALQTKLETLTNQFSDS--KQHIEVLKESLTAKEQRAAILQTEVDALRLR 530
Query: 762 IIEKDAMI 769
+ EK+ M+
Sbjct: 531 LEEKETML 538
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 64.7 bits (156), Expect = 4e-10
Identities = 95/421 (22%), Positives = 174/421 (41%), Gaps = 55/421 (13%)
Query: 437 IVERAQQMVEI---LTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKR 493
+ ERA+ EI LT + R L E + D L ++++ A E+ VK+ T+
Sbjct: 923 VTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 982
Query: 494 -----ESLDKAMRNKL---EGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGH 545
E++ K R K E + L D + D++ + N+ S E + + +++
Sbjct: 983 LSGLDETIAKLTREKKALQEAHQQALDDLQAE-EDKVNSLNKTKSKLEQQVEDLESSLEQ 1041
Query: 546 YASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQA- 604
+ + K KLE +L + + D + LD+ L +L+ ++ ++Q
Sbjct: 1042 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 1101
Query: 605 ---YVEKVEKLQQALTQLQSACE----KREQMERRLRTWLERELDALRTQQKHGNGQPAN 657
+ +K+++LQ + +L+ E R + E++ R+ REL+ L + + G +
Sbjct: 1102 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQ-RSDYARELEELSERLEEAGGVTST 1160
Query: 658 MPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAA-----ATAAAER 712
+EL +++E L L D LEE+T++H AM AA A + AE
Sbjct: 1161 Q--------IELNKKREAEFLKLRRD--------LEEATLQHEAMVAALRKKHADSVAEL 1204
Query: 713 DTTIINHSR-----NGSYGESSLEAHIWQEEEEVVQANRR-----CQDMEYTIKNLHAKI 762
I N R E LE E V ++ C+ +E + K
Sbjct: 1205 GEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKN 1264
Query: 763 IE-KDAMIKVLQQRSR--KDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEK 819
E + ++ ++ Q+SR +AG+ V ++ + ++QT QL EE
Sbjct: 1265 EEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 1324
Query: 820 K 820
K
Sbjct: 1325 K 1325
Score = 54.3 bits (129), Expect = 5e-07
Identities = 93/437 (21%), Positives = 171/437 (39%), Gaps = 75/437 (17%)
Query: 441 AQQMVEILTEENRVLHQELQGYYDNAD----KLHKFEKELQRISEAYESLVKSTTKRESL 496
A Q E L E + L Q LQ + + K EK QR+ E L+ + SL
Sbjct: 1380 AIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSL 1439
Query: 497 ----DKAMRN---------------------------KLEGEIRRLHDFNRDLRDRLETA 525
DK RN L E+ +L + + D+LET
Sbjct: 1440 AAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETV 1499
Query: 526 NRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQAL 585
R+ + E E + E K ++++E+E A ++ A E+ + AL
Sbjct: 1500 KRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE-------AEAAL 1552
Query: 586 SNAQARVIKLEEELREKQAYV--------EKVEKL----QQALTQLQSA--CEKREQMER 631
+ +A++++++ EL + ++ + E++E+L Q+ + +QSA E R + E
Sbjct: 1553 EHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEA 1612
Query: 632 -RLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQK 690
RL+ +E +L+ + Q H N Q A ++ L + + ++ L L+ D + ++
Sbjct: 1613 IRLKKKMEGDLNEIEIQLSHANRQAAETLKH----LRSVQGQLKDTQLHLD-DALRGQED 1667
Query: 691 YLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQD 750
E+ I N E T+ R E L E V + +
Sbjct: 1668 LKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL----LDSNERVQLLHTQNTS 1723
Query: 751 MEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSL 810
+ +T K L +++ + + +DA + ++ A+ + AA ++
Sbjct: 1724 LIHTKKKLETDLMQLQSEV--------EDASRDARNAEEKAKKAITDAAMMAEELKKEQD 1775
Query: 811 TSSQLAEEKKE-EKTWK 826
TS+ L KK E+T K
Sbjct: 1776 TSAHLERMKKNLEQTVK 1792
Score = 42.7 bits (99), Expect = 0.002
Identities = 44/172 (25%), Positives = 78/172 (45%), Gaps = 15/172 (8%)
Query: 517 DLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRR 576
+LR LE R E E + +QN + K+KLE +L +++ ED R
Sbjct: 1688 ELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASR 1747
Query: 577 HIEILDQALSNAQARVIKLEEELREKQ---AYVEKVEK-LQQALTQLQSACEKREQME-- 630
++ A + EEL+++Q A++E+++K L+Q + LQ ++ EQ+
Sbjct: 1748 DARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALK 1807
Query: 631 ------RRLRTWLERELD-ALRTQQKHGNGQPANMPEYNAPALLELVREKEE 675
++L T + REL+ L +QK + +Y + EL + EE
Sbjct: 1808 GGKKQIQKLETRI-RELEFELEGEQKKNTESVKGLRKYER-RVKELTYQSEE 1857
Score = 39.3 bits (90), Expect = 0.018
Identities = 52/244 (21%), Positives = 108/244 (44%), Gaps = 40/244 (16%)
Query: 427 SQQLGPDAFAI---VERAQQMVEILTEENRVLHQEL----QGYYDNADKLHKFEKELQRI 479
S+ L + F + E A +E + EN+ L QE+ + +N +H+ EK ++I
Sbjct: 1475 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 1534
Query: 480 SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED 539
+ + + E+ LE E ++ +L +R+++ ++ E +
Sbjct: 1535 ELEKADIQLALEEAEAA-------LEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQL 1587
Query: 540 K------------AAEGHYASQNKEF-LKEK-----EKLEMELAAVRTASEDHRRHIEIL 581
K A + S+N+ LK+K ++E++L+ + + +H+ +
Sbjct: 1588 KRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSV 1647
Query: 582 DQALSNAQARV---IKLEEELREKQAYVEKVEKLQQA-LTQLQSACEKREQMERRLRTWL 637
L + Q + ++ +E+L+E+ A VE+ L QA + +L++ E+ E R R
Sbjct: 1648 QGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE----RARKLA 1703
Query: 638 EREL 641
E+EL
Sbjct: 1704 EQEL 1707
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 62.8 bits (151), Expect = 1e-09
Identities = 84/405 (20%), Positives = 166/405 (40%), Gaps = 36/405 (8%)
Query: 446 EILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD------KA 499
E L E+N L ++LQ ++ KEL+R E + L+ + D ++
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 500 MRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEK 559
+ KL+ ++ +NR + + E RQ + + + E Q ++ +++EK
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 560 LEMELAAVRTASEDHRRHIEIL---DQALSNAQARVIKLEEELREKQAYV-EKVEKLQQA 615
+ + + E RR E++ ++ + + + + EE++R ++ + EK EK+++
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 616 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEE 675
++ + REQ E+R +E + +R Q+K Q A M E +RE+EE
Sbjct: 397 EEKMHEQEKIREQEEKR------QEEEKIREQEKR-QEQEAKMWRQE-----EKIREQEE 444
Query: 676 RILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGES------- 728
+I E M + E+K E+ IR ++ I E
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
Query: 729 --SLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAM----IKVLQQRSRKDAGK 782
E +W++EE++ + + ++ E + KI E++ M K+ +Q + K
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEK 564
Query: 783 TDSSSLRPARSVPSIAAATGTHSRQ-TSLTSSQLAEEKKEEKTWK 826
+ R I RQ + + +++EEK WK
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/397 (15%), Positives = 166/397 (41%), Gaps = 67/397 (16%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E+ ++ E++ E+ + ++ + ++ +K+ + E+++ + E K + + ++
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHE-DKAAEGHYASQNKEFLKEK 557
R + E ++ R + R+ +++ +++ +E + HE +K E + +E +++
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 482
Query: 558 EKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYV----EKVEKLQ 613
EK+ + R + H + +I Q + +V + EE++RE++ + EK+ + +
Sbjct: 483 EKIHEQEEIWRQKEKMHEQEEKIRKQ-----EEKVWRQEEKIREQEEKIREQEEKMWRQE 537
Query: 614 QALTQLQSACEKREQMERRLRTWLE-------------------------RELDALRTQQ 648
+ + + + + E+M + + W E R+ + +R Q+
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 649 KHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTI----------R 698
+ Q M + E +RE+EE+I E + + E+K E+ + +
Sbjct: 598 EKRQEQEEKMWKQE-----EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 699 HFAMNAAATAAAERDTTIINHSRNGSYGESSL-----------------EAHIWQEEEEV 741
M E++ T+ E + E +W++EE++
Sbjct: 653 EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 712
Query: 742 VQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRK 778
+ + Q+ E ++ K+ E++ ++ +++ ++
Sbjct: 713 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 56.2 bits (134), Expect = 1e-07
Identities = 68/391 (17%), Positives = 163/391 (41%), Gaps = 32/391 (8%)
Query: 446 EILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLE 505
E + + ++ ++ + + +K+H+ EK I E E K + + ++ R + E
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEK----IREQEE---KRQEEEKIREQEKRQEQE 429
Query: 506 GEIRRLHDFNRDLRDRLETANRQLSSREYEGHE-DKAAEGHYASQNKEFLKEKEKLEMEL 564
++ R + R+ +++ +++ +E + HE +K E + +E +++EK+ +
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Query: 565 AAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYV----EKVEKLQQALTQLQ 620
R + H + +I Q + +V + EE++RE++ + EK+ + ++ + + +
Sbjct: 490 EIWRQKEKMHEQEEKIRKQ-----EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQE 544
Query: 621 SACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILAL 680
+ E+M + + W E E + + + E E +RE+EE+
Sbjct: 545 EMWREEEKMHEQEKIW-EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603
Query: 681 EADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEE 740
E M K E+K E+ + E++ I R E + ++EE+
Sbjct: 604 EEKMWKQEEKIREQEE----KIQEQEEKIREQEEKI----REQEEMTQEQEEKMGEQEEK 655
Query: 741 VVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAA 800
+ + + Q+ E T+ KI E++ I+ +++ R+ + +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC-- 713
Query: 801 TGTHSRQTSLTSSQLAEEKKEEKTWKGSIGL 831
++ + + ++EEK W+ + L
Sbjct: 714 ----EQEEKMQEQEEKMRRQEEKMWEQEVRL 740
Score = 36.2 bits (82), Expect = 0.15
Identities = 54/242 (22%), Positives = 98/242 (40%), Gaps = 20/242 (8%)
Query: 538 EDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEE 597
ED+ H Q++E L+ + + ++ + T + L AL +Q V +LE
Sbjct: 108 EDEQKASH---QHQEALRRELEAQVHTIRILTCQKTE------LQMALYYSQHAVKQLEG 158
Query: 598 ELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPAN 657
E R+ + + K L Q SA +++ R L +E DAL +
Sbjct: 159 EARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
Query: 658 MPEYNAPAL--LELVR-EKEERILALEADMTKWEQKYLE------ESTIRHFAMNAAATA 708
+ E NA L+LV EK E L ++ K E+ L ++ H + +
Sbjct: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 278
Query: 709 AAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAM 768
A + N N + E +W++EE++ + + Q+ E I+ KI E++
Sbjct: 279 AKLQAQVEENELWNRLNQQQ--EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 769 IK 770
++
Sbjct: 337 MR 338
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 62.4 bits (150), Expect = 2e-09
Identities = 65/332 (19%), Positives = 143/332 (43%), Gaps = 21/332 (6%)
Query: 457 QELQGYYDNADK-LHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFN 515
Q+LQ D+ K L +LQ E E + ++E K++ ++ +
Sbjct: 249 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQE 308
Query: 516 RDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHR 575
+R++ E RQ +E E + + +E ++E E+ E +R E +
Sbjct: 309 EKIREQEEKMRRQ-EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 576 RHIEILDQALSNAQ-ARVIKLEEELREKQAYVEKVEKLQQALT-----QLQSACEKREQM 629
+I +Q Q A++ + EE++RE++ + + E++ Q Q + E+ E+M
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 630 ERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQ 689
+ + + R+ + +R Q+K Q + E E+++E+EE++ E M + E
Sbjct: 428 QEQEEK-MRRQEEKIREQEKKIREQEEKIREQE-----EMMQEQEEKMGEQEGKMCEQEA 481
Query: 690 KYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSL---EAHIWQEEEEVVQANR 746
K E+ M E++ I E + E +W++EE++ +
Sbjct: 482 KMQEQEE----KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 747 RCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRK 778
+ Q+ E ++ K+ E++ ++ +++ ++
Sbjct: 538 KMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 54.3 bits (129), Expect = 5e-07
Identities = 76/356 (21%), Positives = 146/356 (41%), Gaps = 76/356 (21%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNA-------DKLHKFEKELQRI-SEAYESLVKST 490
++A + +E LT+E L EL Y N +K K +++LQ + SE E +
Sbjct: 177 KKADRYIEELTKERDALSLEL---YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 233
Query: 491 TKRESLDKAM----RNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHY 546
+ L++A + +L+ E L ++L+ Q+ E ++ E
Sbjct: 234 ELKRKLERAKLLLPQQQLQAEADHL---GKELQSVSAKLQAQVEENELWNRLNQQQEEKM 290
Query: 547 ASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYV 606
Q ++ + +EK++ + +R E RR E++ + K E+ R+++
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWE----------KEEKMRRQEEMMW 340
Query: 607 EKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPAL 666
EK EK+++ ++ + REQ E+R +E + +R Q+K Q A M
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKR------QEEEKIREQEKRQE-QEAKMWRQE---- 389
Query: 667 LELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYG 726
E +RE+EE+I E M + E+K E+
Sbjct: 390 -EKIREQEEKIREQEEMMQEQEEKMGEQ-------------------------------- 416
Query: 727 ESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGK 782
E +W++EEE+ + + + E I+ KI E++ I+ ++ ++ K
Sbjct: 417 ----EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Score = 38.1 bits (87), Expect = 0.040
Identities = 54/250 (21%), Positives = 103/250 (41%), Gaps = 20/250 (8%)
Query: 538 EDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEE 597
ED+ H Q++E L+ + + +++ + T + L AL +Q V +LE
Sbjct: 96 EDEQKASH---QHQEALRRELEAQVQTIRILTCQKTE------LQMALYYSQHAVKQLEG 146
Query: 598 ELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPAN 657
E R+ + + K L Q SA +++ R L +E DAL +
Sbjct: 147 EARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 206
Query: 658 MPEYNAPAL--LELVR-EKEERILALEADMTKWEQKYLE------ESTIRHFAMNAAATA 708
+ E NA L+LV EK E L ++ K E+ L ++ H + +
Sbjct: 207 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 266
Query: 709 AAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAM 768
A + N N + E +W++EE++ + + Q+ E I+ K+ ++ M
Sbjct: 267 AKLQAQVEENELWNRLNQQQ--EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 769 IKVLQQRSRK 778
+ +++ R+
Sbjct: 325 MWEKEEKMRR 334
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 62.0 bits (149), Expect = 3e-09
Identities = 97/395 (24%), Positives = 170/395 (43%), Gaps = 40/395 (10%)
Query: 440 RAQQMVEILTEENRV--LHQELQGYYDNADKLHKFEKELQ-RISEAYESLVKSTTKRESL 496
R + +E +T E ++ + +E+ D K K +K ++ RI+E L + K ++L
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 497 DKAMRNKLEGEIRRLHDF---NRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEF 553
K +RNK E I L + R LE A R+L E +D+ AE +Q E
Sbjct: 1026 AK-IRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG-ETTDLQDQIAE--LQAQIDEL 1081
Query: 554 LKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQ 613
+ K E EL +D H + + QA++ +L+E+ ++A K EK +
Sbjct: 1082 KLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQK 1141
Query: 614 QALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREK 673
+ L+ E++E L+T LE LD QQ+ + + E AL E +
Sbjct: 1142 RDLS---------EELEA-LKTELEDTLDTTAAQQELRTKREQEVAELKK-ALEEETKNH 1190
Query: 674 EERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNG---SYGESSL 730
E +I DM + LEE + + A+R + ++ G E +
Sbjct: 1191 EAQI----QDMRQRHATALEELSEQ--------LEQAKRFKANLEKNKQGLETDNKELAC 1238
Query: 731 EAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDS-SSLR 789
E + Q+ + + R+ D + ++ LHAK+ E D + L +++ K + D+ S+L
Sbjct: 1239 EVKVLQQVKAESEHKRKKLDAQ--VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1296
Query: 790 PARSVPSIAAATGTHSRQTSLTSSQ-LAEEKKEEK 823
I A S ++ L +Q L +E+ +K
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK 1331
Score = 53.5 bits (127), Expect = 9e-07
Identities = 83/366 (22%), Positives = 146/366 (39%), Gaps = 61/366 (16%)
Query: 474 KELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSRE 533
K+ IS+ E L K R+ L+KA R KL+GE L D +L+ +++ QL+ +E
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKR-KLDGETTDLQDQIAELQAQIDELKLQLAKKE 1089
Query: 534 YEG------------HEDKAA-----------------EGHYASQNKEFLKEKEKLEMEL 564
E H++ A E AS+NK K+K L EL
Sbjct: 1090 EELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAE-KQKRDLSEEL 1148
Query: 565 AAVRTASEDHRRHIEILDQALSNAQARVIKL----EEELREKQAYVEKVEKLQQALTQLQ 620
A++T ED + + + V +L EEE + +A ++ + Q+ T L+
Sbjct: 1149 EALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR--QRHATALE 1206
Query: 621 SACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPA-------------LL 667
E+ EQ +R + LE+ L T K + + + A + L
Sbjct: 1207 ELSEQLEQA-KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELH 1265
Query: 668 ELVREKEERILALEADMTKWEQKYLEESTIRH--------FAMNAAATAAAERDTTIINH 719
V E + + L +K + + ST+ FA +AA+ + +DT +
Sbjct: 1266 AKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQ 1325
Query: 720 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD 779
+ +L + I Q EEE + ++ E KNL +++ + + +++ D
Sbjct: 1326 EETRQ--KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 780 AGKTDS 785
G +S
Sbjct: 1384 LGTIES 1389
Score = 52.0 bits (123), Expect = 3e-06
Identities = 81/399 (20%), Positives = 159/399 (39%), Gaps = 47/399 (11%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
+E ++ + L EE +L ++LQ + + + L + E ++ R +
Sbjct: 875 LEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEE 934
Query: 498 KAMRNKLEGEIRRLHDFNRDLRDRL--ETANRQLSSREYEGHEDKAAEGH-----YASQN 550
+ L+ E +++ +DL ++L E RQ E E K + QN
Sbjct: 935 EERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQN 994
Query: 551 KEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVE 610
+F+KEK+ +E +A + + + L + + + + LEE L++++ +++E
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 611 KLQQAL----TQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPAL 666
K ++ L T LQ + + L+ L ++ + L Q G + + NA
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL--QGALARGDDETLHKNNA--- 1109
Query: 667 LELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDT--TIINHSRNGS 724
L++VRE L+A + + ++ + E R+ A + E + T + + + +
Sbjct: 1110 LKVVRE-------LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTT 1162
Query: 725 YGESSLEAHIWQE--------EEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRS 776
+ L QE EEE + QDM + HA +E+ + + L+Q
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDM----RQRHATALEE--LSEQLEQAK 1216
Query: 777 R--------KDAGKTDSSSLRPARSVPSIAAATGTHSRQ 807
R K +TD+ L V A H R+
Sbjct: 1217 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRK 1255
Score = 47.8 bits (112), Expect = 5e-05
Identities = 68/332 (20%), Positives = 131/332 (39%), Gaps = 40/332 (12%)
Query: 433 DAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTK 492
D A +E A + + + ++ R L +++ Y ++ E+ S+ E +KS
Sbjct: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKS--- 1684
Query: 493 RESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEG--HYASQN 550
LE EI +L + E A+ + + R E D+ A+ + AS
Sbjct: 1685 -----------LEAEILQLQE---------ELASSERARRHAEQERDELADEITNSASGK 1724
Query: 551 KEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVE 610
L EK +LE +A + E+ + ++E+L+ +V L EL +++ +K +
Sbjct: 1725 SALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD 1784
Query: 611 KLQQAL-TQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPA--LL 667
+Q L Q + K +++E +++ + + AL + Q + A A L+
Sbjct: 1785 NARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLV 1844
Query: 668 ELVREKEERILALEADMTKWEQKYLEESTIRHFAMN--AAATAAAERDTTIINHSRNGSY 725
+K + I D + +Y E+ + M AE + T N SR
Sbjct: 1845 RRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRR--- 1901
Query: 726 GESSLEAHIWQEEEEVVQANRRCQDMEYTIKN 757
+ +E ++ +AN T+KN
Sbjct: 1902 -------KLQRELDDATEANEGLSREVSTLKN 1926
Score = 42.0 bits (97), Expect = 0.003
Identities = 54/241 (22%), Positives = 100/241 (41%), Gaps = 37/241 (15%)
Query: 440 RAQQMVEILTEENRVLHQELQGYYDNADKLHKFE-KELQRISEAYESLVKSTTKRESLDK 498
+A++ L+EE L EL+ D + K Q ++E ++L + T E+ +
Sbjct: 1136 KAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQ 1195
Query: 499 AMRNK-------LEGEIRRLHDFNRDL---RDRLETANRQLSSREYEGHEDKAAEGHYAS 548
MR + L ++ + F +L + LET N++L+ + KA H
Sbjct: 1196 DMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRK 1255
Query: 549 Q------------------NKEFLKEKEKLEMELAAVRTASED-HRRHIEILDQALS--- 586
+ E ++ KL+ EL V T E+ ++ I+ A S
Sbjct: 1256 KLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLES 1315
Query: 587 NAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRT 646
Q L+EE R+K ++ +L++ LQ E+ E+ + LE+++ AL++
Sbjct: 1316 QLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN----LEKQVLALQS 1371
Query: 647 Q 647
Q
Sbjct: 1372 Q 1372
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 61.6 bits (148), Expect = 3e-09
Identities = 69/360 (19%), Positives = 154/360 (42%), Gaps = 26/360 (7%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKEL----QRISEAYESLVKSTTKRE 494
E+ Q+ E + E+ + ++ + + +K+ + E+ + +++ E + + K
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 495 SLDKAMRNKLEGEIRRLHDFNRD---LRDRLETANRQLSSREYEGHEDKAAEGHYASQNK 551
L++ M K E +IR L + + +R++ E + RE E +++ A+ Q +
Sbjct: 367 RLEEMMWEK-EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK--MWRQEE 423
Query: 552 EFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEK 611
+ +++EK+ + + E +I ++ Q + + EE++RE++ + EK
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 612 LQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVR 671
+ + Q K+E+ R + + + +R Q++ Q + E E +R
Sbjct: 484 MHE-----QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE-----EKIR 533
Query: 672 EKEERILALEADMTKWEQKY--LEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESS 729
E+EE+I E M + E+K EE M E++ I R
Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI----REQKEKIRE 589
Query: 730 LEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLR 789
E IW++EE++ + Q+ E + K+ E++ ++ +++ R+ K +R
Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 649
Score = 36.2 bits (82), Expect = 0.15
Identities = 54/242 (22%), Positives = 98/242 (40%), Gaps = 20/242 (8%)
Query: 538 EDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEE 597
ED+ H Q++E L+ + + ++ + T + L AL +Q V +LE
Sbjct: 108 EDEQKASH---QHQEALRRELEAQVHTIRILTCQKTE------LQMALYYSQHAVKQLEG 158
Query: 598 ELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPAN 657
E R+ + + K L Q SA +++ R L +E DAL +
Sbjct: 159 EARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
Query: 658 MPEYNAPAL--LELVR-EKEERILALEADMTKWEQKYLE------ESTIRHFAMNAAATA 708
+ E NA L+LV EK E L ++ K E+ L ++ H + +
Sbjct: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 278
Query: 709 AAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAM 768
A + N N + E +W++EE++ + + Q+ E I+ KI E++
Sbjct: 279 AKLQAQVEENELWNRLNQQQ--EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 769 IK 770
++
Sbjct: 337 MR 338
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 61.6 bits (148), Expect = 3e-09
Identities = 90/477 (18%), Positives = 187/477 (39%), Gaps = 41/477 (8%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
ER ++ E + E+ ++ QE +K+ + E+ +R + E + E + K
Sbjct: 366 ERLREKEERMREQEKMWEQE--------EKMQEEERIREREKKMREEEETMREQEEKMQK 417
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSRE-YEGHEDKAAEGHYASQNKEFLKEK 557
N E E + + RL +L +E + E+K E +++E + +
Sbjct: 418 QEENMWEQEEKEWQ------QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
Query: 558 EKLEMELAAVRTASE---DHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQ 614
EK +R + + + +Q + + + R+ + +E LREK+ + + +K+ Q
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Query: 615 ALTQLQSACEKREQMERRLRTWLE----RELDALRTQQKHGNGQPANMPEYNAPALLELV 670
Q + E+++ E+ +TW + RE + +R ++K + M E E +
Sbjct: 532 ---QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-----EKM 583
Query: 671 REKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSL 730
+E+EE++ E M + E+K ++E + + E D E
Sbjct: 584 QEQEEKMREQEEKMWEQEEK-MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
Query: 731 EAH--IWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSL 788
E +W++EE++ + + ++ E ++ K+ E++ ++ +++ R+ K
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
Query: 789 RPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPP 848
+ + G + + EE+ ++ K L EH E S P LPP
Sbjct: 703 KMWGQEEKM---WGQEEKMWGQEEMREKEERIRDQKEKMQERL---PEHEERCSEPCLPP 756
Query: 849 PPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELF--WPSMASLPSRGRLSTTP 903
S + + A GS + + +LF + P G S P
Sbjct: 757 SKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIP 813
Score = 60.1 bits (144), Expect = 1e-08
Identities = 79/322 (24%), Positives = 138/322 (42%), Gaps = 44/322 (13%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQ---RISEAYESLVKSTTKRES 495
++A + +E LT+E L EL ++L K ELQ R++E+ +S ++ K
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVK--- 211
Query: 496 LDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLK 555
E++R + + L +++T Q E E + E Q ++ +
Sbjct: 212 -----------ELKRKLERAKFLLPQVQTNTLQEEMWRQE-EELREQEKKIRKQEEKMWR 259
Query: 556 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA 615
++E+L + +R E RR + R+ + E+ELRE++ + + +KL++
Sbjct: 260 QEERLREQEGKMREQEEKMRRQ-----------EKRLREQEKELREQEKELREQKKLREQ 308
Query: 616 LTQLQSACEKREQMERRLRTWLE---RELDALRTQQKHGNGQPANM--PEYNAPALLELV 670
Q+Q EK + E ++R E R+ + L Q+K Q M E E +
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 671 REKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSL 730
REKEER+ E M + E+K EE IR E + T+ R
Sbjct: 369 REKEERMREQE-KMWEQEEKMQEEERIRE-----REKKMREEEETM----REQEEKMQKQ 418
Query: 731 EAHIWQEEEEVVQANRRCQDME 752
E ++W++EE+ Q R + E
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKE 440
Score = 51.6 bits (122), Expect = 3e-06
Identities = 58/326 (17%), Positives = 139/326 (42%), Gaps = 30/326 (9%)
Query: 464 DNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLE 523
D H+ ++ L+R EA + ++ T +++ + + R+ D N L + +
Sbjct: 71 DEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGN--LGESKD 128
Query: 524 TANRQLSSREYEGHEDKAAEGHYASQNK------EFLKEKEKLEMELAAVRTASEDHRRH 577
A R S + G +A K E KE++ L +EL +E+ ++
Sbjct: 129 LAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKK 188
Query: 578 IEILDQALSNAQARVIKLEEELREKQAYVEKVEKL--QQALTQLQSACEKREQMERRLRT 635
L + L A++ +++ ++E + +E+ + L Q LQ ++E+ R
Sbjct: 189 NAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK 248
Query: 636 WLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEES 695
+ ++ + + Q++ Q M E E +R +E+R+ E ++ + E++ E+
Sbjct: 249 KIRKQEEKMWRQEERLREQEGKMREQE-----EKMRRQEKRLREQEKELREQEKELREQK 303
Query: 696 TIRHFAMNAAATAAAERDTTIINHSRNGSYGESSL---EAHIWQEEEEVVQANRRCQDME 752
+R E++ + E + E +W++EE + + ++ ++ E
Sbjct: 304 KLR------------EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
Query: 753 YTIKNLHAKIIEKDAMIKVLQQRSRK 778
+++ ++ E+D ++ ++R R+
Sbjct: 352 QKMRDQEERMWEQDERLREKEERMRE 377
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 60.8 bits (146), Expect = 6e-09
Identities = 78/357 (21%), Positives = 149/357 (41%), Gaps = 45/357 (12%)
Query: 446 EILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD------KA 499
E L E+N L ++LQ ++ KEL+R E + L+ + D ++
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 500 MRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEK 559
+ KL+ ++ +NR + + E RQ E+K E Q +E EK
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQ---------EEKIQEWEEKIQEQE-----EK 383
Query: 560 LEMELAAVRTASEDHRRHIEIL---DQALSNAQARVIKLEEELREKQAYV-EKVEKLQQA 615
+ + +R E RR E++ ++ + + + + EE++R ++ + EK EK+++
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 443
Query: 616 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEE 675
++ + REQ E+R +E + +R Q+K Q A M E +RE+EE
Sbjct: 444 EEKMHEQEKIREQEEKR------QEEEKIREQEKRQE-QEAKMWRQE-----EKIREQEE 491
Query: 676 RILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGES------- 728
+I E M + E+K E+ IR ++ I E
Sbjct: 492 KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEK 551
Query: 729 --SLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKT 783
E +W++EE++ + ++ E + KI E++ I+ +++ R+ T
Sbjct: 552 IRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMT 608
Score = 60.8 bits (146), Expect = 6e-09
Identities = 80/440 (18%), Positives = 184/440 (41%), Gaps = 64/440 (14%)
Query: 427 SQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQ----RISEA 482
+ LG + ++ + Q VE NR+ Q+ + + +K+ ++E+++Q +I E
Sbjct: 328 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 387
Query: 483 YESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL----------ETANRQLSSR 532
E + + K ++ M K E ++RR + + +++ E R+L +
Sbjct: 388 EEKIREQEEKMRRQEEMMWEK-EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 446
Query: 533 EYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARV 592
+E ++K E Q +E ++E+EK + + A + E R ++ + + ++
Sbjct: 447 MHE--QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ----EEKIREQEEKM 500
Query: 593 IKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGN 652
+ EE++ E++ E+ ++ +Q Q + ++ R + + + + +R Q++
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 653 GQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLE-ESTIRHFAMNAAATAAAE 711
Q M + E +RE+EE++ E + + E+K E E IR +
Sbjct: 561 RQEEKMHDQE-----EKIREQEEKVWRQEEKIREQEEKIREQEEKIRE-----------Q 604
Query: 712 RDTTIINHSRNGSYGESSLEAH--IWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMI 769
+ T + G E E + ++EE++ + + ++ E I+ KI E++ M+
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Query: 770 KVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSI 829
+ +++ + K ++ + + ++EEK W+ +
Sbjct: 665 QEQEEKMWEQEEK--------------------MCEQEEKMQEQEEKMRRQEEKMWEQEV 704
Query: 830 GLLLG----KEHHEHASAPL 845
L +EH EH A +
Sbjct: 705 RLRQQEEKMQEHQEHLEAAI 724
Score = 42.7 bits (99), Expect = 0.002
Identities = 75/412 (18%), Positives = 157/412 (38%), Gaps = 69/412 (16%)
Query: 464 DNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLE 523
D H+ ++ L+R EA ++ T +++ + + +++L RDL RL
Sbjct: 170 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 229
Query: 524 TANRQLSSREYEGHEDKAAEGHYASQNK------EFLKEKEKLEMELAAVRTASEDHR-- 575
S ++ G ++A + K E KE++ L +EL E+ +
Sbjct: 230 ------DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 283
Query: 576 -----RHIEILDQALSNAQARVIKLEEEL---------REKQAYVEKVEK-LQQALTQLQ 620
+++++ S Q V +L+ +L ++ QA + + K LQ +LQ
Sbjct: 284 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 343
Query: 621 SACEKRE--------------QMERRLRTW---LERELDALRTQQKHGNGQPANM----- 658
+ E+ E + E +++ W ++ + + +R Q++ Q M
Sbjct: 344 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 403
Query: 659 ----PEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDT 714
E E++ EKEE++ E M + E+K E H ++
Sbjct: 404 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 463
Query: 715 TIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQ 774
I EA +W++EE++ + + ++ E + KI E++ K+ ++
Sbjct: 464 EKIREQEK----RQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE---KIREE 516
Query: 775 RSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWK 826
R++ + R I ++ + + K+EEK W+
Sbjct: 517 EKRQEQEEM-------WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWR 561
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 60.8 bits (146), Expect = 6e-09
Identities = 77/295 (26%), Positives = 135/295 (45%), Gaps = 34/295 (11%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
V A + L E R LH++L+ + ++ K E+ELQR+ E L + T E+
Sbjct: 599 VTEANGKLSQLEFEKRQLHRDLEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETAT 658
Query: 498 KAMRNKLEGEIRRLHDFNRDLR---DRLETANRQLSSREYEGHEDKA--AEGHYASQNKE 552
+ + LE E + L NR LR D L+ + QL E + + A E +
Sbjct: 659 EKV-EALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMR 717
Query: 553 FLKEK-EKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEK 611
F K ++E E + E+ R+++++L +AL R+ EL + E + +
Sbjct: 718 FTSTKLAQMERENQQLEREKEELRKNVDLL-KALGKKSERL-----ELSYQSVSAENL-R 770
Query: 612 LQQALTQLQSACEKREQMERRL------RTWLERELDALRTQQKHGNGQPANMPEYNAPA 665
LQQ+ L+S+ K + +E L R L R+L+ALR G E + A
Sbjct: 771 LQQS---LESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEG-----AEKDRKA 822
Query: 666 LLELVR--EKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIIN 718
L + V EK++++L EA W+Q L+++ + + A +A E+++ ++
Sbjct: 823 LEQEVAQLEKDKKLLEKEAKRL-WQQVELKDAVLDD---STAKLSAVEKESRALD 873
Score = 49.3 bits (116), Expect = 2e-05
Identities = 90/429 (20%), Positives = 179/429 (41%), Gaps = 70/429 (16%)
Query: 447 ILTEENRVLHQELQGYYDNADKLHKFEKE-LQRISEAYESLVKSTTKRESLDKAMRNKLE 505
IL E +L ++L DK+H+ EKE LQ S+ ++ + T ++ +++ + +
Sbjct: 358 ILIETKAMLEEQLTAARARGDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENMV 417
Query: 506 GEIRRLHDFNR---------------DLRD-------------------RLETANRQLSS 531
EI + N DL D +LE N+ L S
Sbjct: 418 LEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQS 477
Query: 532 REYEGHEDKAAE--------GHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQ 583
+G D + G +N + K+ EKL+ +L + +++D +E L +
Sbjct: 478 -TIQGLRDASLVLEESGLKCGELEKENHQLSKKIEKLQTQLEREKQSNQD----LETLSE 532
Query: 584 ALSNAQARVIKLEEELR-EKQAYVEKVEKLQQALTQLQSACEKREQM--ERRLRTWLERE 640
L + ++ E L+ +K ++ +E+ + L + + +R Q+ E R++ +E+E
Sbjct: 533 ELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAMWSLRERSQVSSEARMKD-VEKE 591
Query: 641 LDALRTQQKHGNGQPANMPEYNAPAL---LELVREKEERILALEADMTKWEQK------- 690
AL NG+ + + E+ L LE +EK ER LE ++ + +++
Sbjct: 592 NKALHQTVTEANGKLSQL-EFEKRQLHRDLEQAKEKGERAEKLERELQRLQEENGRLARK 650
Query: 691 --YLEESTIRHFAMNAAATAAAERDTTI---INHSRNGSYGESSLEAHIWQEEEEVVQAN 745
LE +T + A+ + + T+ ++ +N S LE Q + E ++
Sbjct: 651 VTSLETATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELR 710
Query: 746 RRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHS 805
R + M +T L A++ ++ ++ ++ RK+ + + R S + + +
Sbjct: 711 RLVETMRFTSTKL-AQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENL 769
Query: 806 R-QTSLTSS 813
R Q SL SS
Sbjct: 770 RLQQSLESS 778
Score = 45.1 bits (105), Expect = 3e-04
Identities = 65/265 (24%), Positives = 116/265 (43%), Gaps = 32/265 (12%)
Query: 448 LTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTK-RESLDKAMRNK--L 504
+ EN+ L +E + N D L K+ +R+ +Y+S+ + ++SL+ + L
Sbjct: 726 MERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQTL 785
Query: 505 EGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED--KAAEGHYAS--QNKEFLKEKEKL 560
E E+ L + LR LE +L++ + EG E KA E A ++K+ L+++ K
Sbjct: 786 ESELGELEAERQALRRDLEAL--RLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAKR 843
Query: 561 EMELAAVRTASEDH--------RRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKL 612
+ ++ A D + LD+ L+ + KL+E ++ + ++V
Sbjct: 844 LWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDLTKQVTVH 903
Query: 613 QQALTQLQSACE----KREQMERRL--------RTWLERELDALRTQQKHGNGQPANMPE 660
+ LT L+ K +Q+ L + L REL L + G+ + E
Sbjct: 904 ARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNREL--LLQEDDSGSDTKYKILE 961
Query: 661 -YNAPALLELVREKEERILALEADM 684
N AL + KEE+I+ LEA M
Sbjct: 962 GRNESALKTTLAMKEEKIVLLEAQM 986
Score = 41.6 bits (96), Expect = 0.004
Identities = 110/536 (20%), Positives = 195/536 (36%), Gaps = 96/536 (17%)
Query: 439 ERAQQMVEILTEEN---RVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
ER E L ++ + LH+ L+ + + H L+R +E E TT+RE+
Sbjct: 1179 ERQSAEYEALIRQHSCLKTLHRNLELEHKELGERHG--DMLKRKAELEEREKVLTTEREA 1236
Query: 496 LDKAMR-----------------------NKLEGEIRRLHDFNRDLRDRLETANRQLSSR 532
L + R ++L+GE LH ++L+ L N QL
Sbjct: 1237 LQQEQRTNALAMGENQRLRGELDRVNFLHHQLKGEYEELHAHTKELKTSLN--NAQLELN 1294
Query: 533 EYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARV 592
++ D+ E H Q + K EL + + + H +L Q +Q
Sbjct: 1295 RWQARFDELKEQH---QTMDISLTKLDNHCELLSRLKGNLEEENH-HLLSQIQLLSQQNQ 1350
Query: 593 IKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGN 652
+ LE+ + K+ Y E+ ++ L L+ EK E + + Q K +
Sbjct: 1351 MLLEQNMENKEQYHEEQKQYIDKLNALRRHKEKLE--------------EKIMDQYKFYD 1396
Query: 653 GQPANMPEY-NAPALLELVREKEE---RILALEADMTKWEQKYLEESTIRHFAMNAAATA 708
P + A AL++L++ K+E L D W+ LE S + A+ A
Sbjct: 1397 PPPKKKNHWIGAKALVKLIKPKKEGSRERLKSTVDSPPWQ---LESS-------DPASPA 1446
Query: 709 AAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAM 768
A++ + + + G + E + + + D++ + H +++
Sbjct: 1447 ASQPLRSQAENPDTPALGSNCAE----ERDAHNGSVGKGPGDLKPKRGSPHRGSLDRTDA 1502
Query: 769 IKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSS--QLAEEKKEEKTWK 826
L RS + + S + PS + H +T +S L E E +
Sbjct: 1503 STDLAMRSWPSELGSRTCSTSATTTAPSNSTPIARHPGRTKGYNSDDNLCEPSLEFEV-- 1560
Query: 827 GSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELF 886
H ++ S P SS+ S+ SS + K SS Q +E F
Sbjct: 1561 --------PNHRQYVSRP----------SSLESSRNTSSNSSPLNLKGSSEQLHGRSESF 1602
Query: 887 WPSMASLPSRG-----RLSTTPAHSPVLKH--PAAKGTAEKLENSPGHGKSPDHRG 935
S +PSR R ++TP + + +H P + E + G +P + G
Sbjct: 1603 -SSEDLIPSRDLATLPREASTPGRNALGRHEYPLPRNGPLPQEGAQKRGTAPPYVG 1657
Score = 35.0 bits (79), Expect = 0.33
Identities = 46/177 (25%), Positives = 79/177 (44%), Gaps = 24/177 (13%)
Query: 436 AIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKS-TTKRE 494
A+++ + + + +E+R L +EL D A KL + EK+ + +++ ++ TT RE
Sbjct: 853 AVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDLTKQVTVHARTLTTLRE 912
Query: 495 S--LDKAMRNKLEGEIRRLHDFNRDLRDRLETA--NRQLSSREYEGHED---KAAEGHYA 547
L+K +L E+ + L LE NR+L +E + D K EG
Sbjct: 913 DLVLEKLKSQQLSSELDK-------LSQELEKVGLNRELLLQEDDSGSDTKYKILEGRNE 965
Query: 548 SQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLE-EELREKQ 603
S K L KE+ + L A R +E ++ +++K E E LR+ Q
Sbjct: 966 SALKTTLAMKEEKIVLLEAQMEEKASLNRQLE--------SELQMLKKECETLRQNQ 1014
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 59.7 bits (143), Expect = 1e-08
Identities = 92/401 (22%), Positives = 167/401 (41%), Gaps = 77/401 (19%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
V + ++E +EN +L +E+ ++NA K K LQ + E +S K S++
Sbjct: 343 VHHLESLLEQKEKENSMLREEMHRRFENAPDSAK-TKALQTVIEMKDS------KISSME 395
Query: 498 KAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEK 557
+ +R+ LE EI+ L +N LS+ E E E+ Y S +K F+K K
Sbjct: 396 RGLRD-LEEEIQMLK------------SNGALSTEERE--EEMKQMEVYRSHSK-FMKNK 439
Query: 558 --------EKLEMELAAVRTASE-------DHRRHIEILDQALSNAQARVIKLEEELREK 602
+ + EL A++T E D ++HIE+L ++L+ + R L+ E+
Sbjct: 440 IGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDAL 499
Query: 603 QAYVEKVE-KLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEY 661
+ +E+ E L + Q+Q E++ + L+ LD + N+ +
Sbjct: 500 RLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD-LKDMLDV--------KERKVNVLQK 550
Query: 662 NAPALLELVREKE-------ERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDT 714
L E +R+KE ER+ +L+AD T + A+ A AE++
Sbjct: 551 KIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDT-----------ALTTLEEALAEKER 599
Query: 715 TIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQ 774
TI E +++EE+ + +D++ + L + EK+A + L++
Sbjct: 600 TIERLKEQRDRDER-------EKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKE 652
Query: 775 RSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQL 815
A SS L+ + ++ A + SQL
Sbjct: 653 H----ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQL 689
Score = 41.2 bits (95), Expect = 0.005
Identities = 42/186 (22%), Positives = 87/186 (46%), Gaps = 8/186 (4%)
Query: 466 ADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETA 525
A+ HK + E ++ ++ +++ +RE +L+ +R+ D +L + L +
Sbjct: 766 ANLKHKEQVEKKKSAQ----MLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRES 821
Query: 526 NRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQAL 585
+ + RE ++++A + Q +E L EK++ EL +++ ++ + + L
Sbjct: 822 VQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHL 881
Query: 586 SNAQARVIK-LEEELREKQ-AYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDA 643
+N +A K LEE L KQ A + + + + L+ + K++ E L+RE D
Sbjct: 882 TNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAA--LKREKDR 939
Query: 644 LRTQQK 649
L Q K
Sbjct: 940 LVQQLK 945
Score = 39.7 bits (91), Expect = 0.014
Identities = 78/437 (17%), Positives = 155/437 (35%), Gaps = 60/437 (13%)
Query: 422 PAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISE 481
P + L D + + ++ ++ EEN+ + +Q D RI
Sbjct: 192 PELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDEL-----------RIQR 240
Query: 482 AYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKA 541
L + + + + + E +RLH + L + L E K
Sbjct: 241 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ 300
Query: 542 AEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRR---------HIEILDQALSNAQARV 592
++++ K E L+ + + + EDH R H+ L+ L +
Sbjct: 301 TLN---ARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKEN 357
Query: 593 IKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRT----QQ 648
L EE+ + K + T ++ K MER LR LE E+ L++
Sbjct: 358 SMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRD-LEEEIQMLKSNGALST 416
Query: 649 KHGNGQPANMPEYNAPA---------LLELVREKEERILALEADMTKWEQKYLEESTIRH 699
+ + M Y + + + + + K+ +LAL+ + ++ + +H
Sbjct: 417 EEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSK--QH 474
Query: 700 FAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEY------ 753
+ + A E+ I+ +L + ++E + + ++ QDM
Sbjct: 475 IEVLKESLTAKEQRAAILQTE------VDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA 528
Query: 754 -TIKNLHAKIIEKDAMIKVLQ------QRSRKDAGKTDSSSLRPARSVPSIAAATGTHSR 806
I +L + K+ + VLQ Q +D K SS +S+ A T T +
Sbjct: 529 GEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ--ADTTNTDTA 586
Query: 807 QTSLTSSQLAEEKKEEK 823
T+L + +E+ E+
Sbjct: 587 LTTLEEALAEKERTIER 603
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 59.7 bits (143), Expect = 1e-08
Identities = 89/419 (21%), Positives = 176/419 (42%), Gaps = 55/419 (13%)
Query: 436 AIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKE-LQRISEAYESLVKSTTKRE 494
A VE ++ ++L E +L +L+G +DKLH+ EKE LQ ++ ++ ++ R+
Sbjct: 344 ARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRK 403
Query: 495 SLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFL 554
+++ M + E+ + + L L Q+S + + GH N+
Sbjct: 404 KIEELMEENMTLEMAQKQSMDESL--HLGWELEQISRTSELSEAPQKSLGH--EVNELTS 459
Query: 555 KEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQ 614
KLEME ++ E+ R + D NA ++++K+E +E Q +KVE L+
Sbjct: 460 SRLLKLEMENQSLTKTVEELRTTV---DSVEGNA-SKILKME---KENQRLSKKVEILEN 512
Query: 615 ALTQLQSACE-----------KREQMERRLRTW---LERELDALRTQQKHGNGQPANMPE 660
+ Q + + + ++ Q+E+ + T ER++ L + +H N +++ +
Sbjct: 513 EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ 572
Query: 661 YNAPALLELVR--EKEERIL--------------ALEADMTKWEQKYLEESTIRHFAMNA 704
+ + V+ EKE +IL E K E ++ +E R +
Sbjct: 573 RSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELEN 632
Query: 705 AATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIE 764
+ + + N +EA + QE E+ + NR+ + + KNL ++
Sbjct: 633 ELHHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLTFQL-- 689
Query: 765 KDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEK 823
+ K+ + D +L R+V S+ A+ Q L + +L EK++ K
Sbjct: 690 ---------ESLEKENSQLDEENLELRRNVESLKCAS-MKMAQLQLENKELESEKEQLK 738
Score = 50.1 bits (118), Expect = 1e-05
Identities = 74/411 (18%), Positives = 164/411 (39%), Gaps = 51/411 (12%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
+++ + ++ L EN+ L + L+ ++ +L + EKE + + + L K + E +
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Query: 498 KAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEK 557
K +R + E + L + N + LE N+ LS E +NKE +K
Sbjct: 839 KRLRQQAEIKDTTLEENNVKI-GNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897
Query: 558 E-------KLEMELAAVRTASEDHRRHIEIL-----------------DQALSNAQARVI 593
L +L + + ++ +E L +Q+ +++ +++
Sbjct: 898 TIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLL 957
Query: 594 KLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHG-- 651
+ + E K++ K EK+ +L+ + +Q+ + L+T +++ +AL+ +Q
Sbjct: 958 ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT-VKKNYEALKQRQDEERM 1016
Query: 652 -------NGQPANMPEYNAPALLELVREKEERI--------LALEADMTKWEQKYLEEST 696
+G+ + EL++ K+ I L E K + K LE
Sbjct: 1017 VQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN 1076
Query: 697 ----IRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDME 752
+ A+ + E++TT+ + S+L + + ++ N + +
Sbjct: 1077 NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNS----QSTSLMNQNAQLLIQQ 1132
Query: 753 YTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGT 803
+++N + +I++ +K L KD K + R A S+ + GT
Sbjct: 1133 SSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGT 1183
Score = 47.0 bits (110), Expect = 9e-05
Identities = 53/230 (23%), Positives = 102/230 (44%), Gaps = 37/230 (16%)
Query: 451 ENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRR 510
E R + +EL+ Y + ++ + E EL + + E L K T + + + LE E
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIE-ALEQENSE 667
Query: 511 LHDFNRDLRDRLETANR---QLSSREYEGHEDKAAEGHYASQNKEFLK----EKEKLEME 563
L NR L+ L++ QL S E E + E +N E LK + +L++E
Sbjct: 668 LERENRKLKKTLDSFKNLTFQLESLEKENSQ-LDEENLELRRNVESLKCASMKMAQLQLE 726
Query: 564 LAAVRTASEDHRRHIEI------------------------LDQALSNAQARVIKLEEEL 599
+ + E ++ +E+ L + L N+ ++ +LE EL
Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Query: 600 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQK 649
++ + + + LQ+ L +L+ + ++ EQ+E+ ++ LE+E L +K
Sbjct: 787 QDLEM---ENQTLQKNLEELKISSKRLEQLEKENKS-LEQETSQLEKDKK 832
Score = 45.4 bits (106), Expect = 2e-04
Identities = 82/433 (18%), Positives = 170/433 (39%), Gaps = 64/433 (14%)
Query: 439 ERAQQM---VEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
ERA+++ + L +EN +L +++ +K+ E+E + L K+ ++
Sbjct: 625 ERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKN 684
Query: 496 LDKAMRNKLEGEIRRLHDFNRDLRDRLET--------ANRQLSSREYEGHEDKAAEGHYA 547
L + + LE E +L + N +LR +E+ A QL ++E E +++ +G
Sbjct: 685 LTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG--L 741
Query: 548 SQNKEFLKEKEKLEM-------ELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL- 599
K K+ E+LE+ E ++ E+ + I+ L+ L + + L++ L
Sbjct: 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Query: 600 -------------REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRT 646
+E ++ ++ +L++ QL+ ++ Q T LE +
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 647 QQKHGNGQPANMPEY--NAPALLELVREKEERI----------------LALEADMTKWE 688
+K + Y + L EL +E +E + L E T+
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 689 QKYLEEST--IRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANR 746
LE+ T + +N E+ T + S ES+L+ + +EE++
Sbjct: 922 NNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEA 981
Query: 747 RCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSR 806
R ++ + L ++ + L+QR ++ R +S P I+ R
Sbjct: 982 RLEESTNYNQQLRQELKTVKKNYEALKQRQDEE---------RMVQSSPPISGEDNKWER 1032
Query: 807 QTSLTSSQLAEEK 819
++ T+ +L + K
Sbjct: 1033 ESQETTRELLKVK 1045
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 59.7 bits (143), Expect = 1e-08
Identities = 89/419 (21%), Positives = 176/419 (42%), Gaps = 55/419 (13%)
Query: 436 AIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKE-LQRISEAYESLVKSTTKRE 494
A VE ++ ++L E +L +L+G +DKLH+ EKE LQ ++ ++ ++ R+
Sbjct: 344 ARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRK 403
Query: 495 SLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFL 554
+++ M + E+ + + L L Q+S + + GH N+
Sbjct: 404 KIEELMEENMTLEMAQKQSMDESL--HLGWELEQISRTSELSEAPQKSLGH--EVNELTS 459
Query: 555 KEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQ 614
KLEME ++ E+ R + D NA ++++K+E +E Q +KVE L+
Sbjct: 460 SRLLKLEMENQSLTKTVEELRTTV---DSVEGNA-SKILKME---KENQRLSKKVEILEN 512
Query: 615 ALTQLQSACE-----------KREQMERRLRTW---LERELDALRTQQKHGNGQPANMPE 660
+ Q + + + ++ Q+E+ + T ER++ L + +H N +++ +
Sbjct: 513 EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ 572
Query: 661 YNAPALLELVR--EKEERIL--------------ALEADMTKWEQKYLEESTIRHFAMNA 704
+ + V+ EKE +IL E K E ++ +E R +
Sbjct: 573 RSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELEN 632
Query: 705 AATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIE 764
+ + + N +EA + QE E+ + NR+ + + KNL ++
Sbjct: 633 ELHHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLTFQL-- 689
Query: 765 KDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEK 823
+ K+ + D +L R+V S+ A+ Q L + +L EK++ K
Sbjct: 690 ---------ESLEKENSQLDEENLELRRNVESLKCAS-MKMAQLQLENKELESEKEQLK 738
Score = 48.9 bits (115), Expect = 2e-05
Identities = 74/410 (18%), Positives = 163/410 (39%), Gaps = 50/410 (12%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
+++ + ++ L EN+ L + L+ ++ +L + EKE + + + L K + E +
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Query: 498 KAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEK 557
K +R + E + L + N + LE N+ LS E +NKE +K
Sbjct: 839 KRLRQQAEIKDTTLEENNVKI-GNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897
Query: 558 E-------KLEMELAAVRTASEDHRRHIEIL----------------DQALSNAQARVIK 594
L +L + + ++ +E L D+ ++ + ++++
Sbjct: 898 TIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE 957
Query: 595 LEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHG--- 651
+ E K++ K EK+ +L+ + +Q+ + L+T +++ +AL+ +Q
Sbjct: 958 SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT-VKKNYEALKQRQDEERMV 1016
Query: 652 ------NGQPANMPEYNAPALLELVREKEERI--------LALEADMTKWEQKYLEEST- 696
+G+ + EL++ K+ I L E K + K LE
Sbjct: 1017 QSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNN 1076
Query: 697 ---IRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEY 753
+ A+ + E++TT+ + S+L + + ++ N + +
Sbjct: 1077 NLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNS----QSTSLMNQNAQLLIQQS 1132
Query: 754 TIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGT 803
+++N + +I++ +K L KD K + R A S+ + GT
Sbjct: 1133 SLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGT 1182
Score = 47.0 bits (110), Expect = 9e-05
Identities = 53/230 (23%), Positives = 102/230 (44%), Gaps = 37/230 (16%)
Query: 451 ENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRR 510
E R + +EL+ Y + ++ + E EL + + E L K T + + + LE E
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIE-ALEQENSE 667
Query: 511 LHDFNRDLRDRLETANR---QLSSREYEGHEDKAAEGHYASQNKEFLK----EKEKLEME 563
L NR L+ L++ QL S E E + E +N E LK + +L++E
Sbjct: 668 LERENRKLKKTLDSFKNLTFQLESLEKENSQ-LDEENLELRRNVESLKCASMKMAQLQLE 726
Query: 564 LAAVRTASEDHRRHIEI------------------------LDQALSNAQARVIKLEEEL 599
+ + E ++ +E+ L + L N+ ++ +LE EL
Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Query: 600 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQK 649
++ + + + LQ+ L +L+ + ++ EQ+E+ ++ LE+E L +K
Sbjct: 787 QDLEM---ENQTLQKNLEELKISSKRLEQLEKENKS-LEQETSQLEKDKK 832
Score = 43.5 bits (101), Expect = 0.001
Identities = 78/403 (19%), Positives = 170/403 (42%), Gaps = 27/403 (6%)
Query: 437 IVERAQQMVEIL-TEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
+V+RA ++ L T ++ ++L+ N D L K EL++I E L+ +
Sbjct: 893 LVKRATIDIKTLVTLREDLVSEKLKTQQMNND-LEKLTHELEKIGLNKERLLHDEQSTDD 951
Query: 496 LDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLK 555
K + +KLE +++ + + LE R S Y ++ E +N E LK
Sbjct: 952 RYKLLESKLESTLKKSLEIKEEKIAALEA--RLEESTNY--NQQLRQELKTVKKNYEALK 1007
Query: 556 EKEKLE-MELAAVRTASEDHR--RHIEILDQALSNAQARVIKLEEE----LREKQAYVEK 608
+++ E M ++ + ED++ R + + L + R+I++E EKQA +
Sbjct: 1008 QRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQ 1067
Query: 609 VEKLQQALTQLQS---ACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPA 665
+++L+ LQ+ A +++ + T L+ + L+ + N Q ++ NA
Sbjct: 1068 LKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQL 1127
Query: 666 LLE--LVREKEERILALEADMTKWEQKYLEESTIR-HFAMNAAATAAAERDTTIINHSRN 722
L++ + + E ++ D+ K L +S I+ H + A ++I+
Sbjct: 1128 LIQQSSLENENESVIKEREDL-----KSLYDSLIKDHEKLELLHERQASEYESLISKHGT 1182
Query: 723 GSYGESSLEAHIWQEEE---EVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD 779
+LE E+ ++++ + +D+E +K K++ ++ + + +K
Sbjct: 1183 LKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKL 1242
Query: 780 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEE 822
G+ D + ++ + H SL ++ E+ + E
Sbjct: 1243 CGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLE 1285
Score = 41.6 bits (96), Expect = 0.004
Identities = 79/423 (18%), Positives = 164/423 (38%), Gaps = 45/423 (10%)
Query: 439 ERAQQM---VEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
ERA+++ + L +EN +L +++ +K+ E+E + L K+ ++
Sbjct: 625 ERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKN 684
Query: 496 LDKAMRNKLEGEIRRLHDFNRDLRDRLET--------ANRQLSSREYEGHEDKAAEGHYA 547
L + + LE E +L + N +LR +E+ A QL ++E E +++ +G
Sbjct: 685 LTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG--L 741
Query: 548 SQNKEFLKEKEKLEM-------ELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL- 599
K K+ E+LE+ E ++ E+ + I+ L+ L + + L++ L
Sbjct: 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Query: 600 -------------REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRT 646
+E ++ ++ +L++ QL+ ++ Q T LE +
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 647 QQKHGNGQPANMPEY--NAPALLELVREKEERILALEAD---MTKWEQKYLEESTIRHFA 701
+K + Y + L EL +E +E + D + + + E
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 702 MNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAK 761
N E + +N R +S+ + + E + + + E I L A+
Sbjct: 922 NNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEAR 981
Query: 762 IIEKDAMIKVLQQ-----RSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLA 816
+ E + L+Q + +A K R +S P I+ R++ T+ +L
Sbjct: 982 LEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELL 1041
Query: 817 EEK 819
+ K
Sbjct: 1042 KVK 1044
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 59.7 bits (143), Expect = 1e-08
Identities = 98/400 (24%), Positives = 163/400 (40%), Gaps = 69/400 (17%)
Query: 451 ENRV--LHQELQGYYDNADKLHKFEKELQRI-SEAYESLVKSTTKRESLDKAMRNKLEGE 507
EN+V L +E+ G + KL K +K LQ + + L K +L KA + KLE +
Sbjct: 976 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKA-KTKLEQQ 1034
Query: 508 IRRLH---DFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQN-KEFLKEK-EKLEM 562
+ L + + L LE A R+L EG A E ++N K+ L EK +K E
Sbjct: 1035 VDDLEGSLEQEKKLCMDLERAKRKL-----EGDLKLAQESTMDTENDKQQLNEKLKKKEF 1089
Query: 563 ELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSA 622
E++ ++ ED + L + + QAR+ +LEEE+ ++A K EK
Sbjct: 1090 EMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEK----------- 1138
Query: 623 CEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEA 682
R+ L REL+ + + + G + A +E+ +++E +
Sbjct: 1139 ----------QRSDLSRELEEISERLEEAGGATS--------AQIEMNKKREAEFQKMRR 1180
Query: 683 DMTKWEQKYLEESTIRHFAMNAA-----ATAAAERDTTI-----INHSRNGSYGESSLEA 732
D LEEST++H A AA A + AE I + E +E
Sbjct: 1181 D--------LEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEI 1232
Query: 733 HIWQEEEEVV---QAN--RRCQDMEYTIKNLHAKIIEKDAMIKVL---QQRSRKDAGKTD 784
+ E V +AN + C+ +E + + K E+ +I L + R ++G+
Sbjct: 1233 NDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFS 1292
Query: 785 SSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKT 824
V ++ ++Q QL EE K + T
Sbjct: 1293 RQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKST 1332
Score = 50.4 bits (119), Expect = 8e-06
Identities = 81/367 (22%), Positives = 144/367 (39%), Gaps = 58/367 (15%)
Query: 473 EKELQRISEAYES----LVKSTTKRESLDKAM------RNKLEGEIRRLHDFNRDLRDRL 522
EKE+ + E +E L K+ KR+ L++ M +N L+ +++ D D +R
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERC 909
Query: 523 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD 582
+ + E + E N E +K KLE E + ++ +D + ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 583 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMER-------RLRT 635
+ + +V L EE+ + K+ K ++AL + QME + +T
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKT 1029
Query: 636 WLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEES 695
LE+++D L E ++L R K + LE D+ K +ES
Sbjct: 1030 KLEQQVDDLE-----------GSLEQEKKLCMDLERAKRK----LEGDL-----KLAQES 1069
Query: 696 TIRHFAMNAAATAAAERDTTIINHS-RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYT 754
T+ E D +N + + S+L+ I E+ +Q ++
Sbjct: 1070 TM-----------DTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKK------- 1111
Query: 755 IKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPS-IAAATGTHSRQTSLTSS 813
IK L A+I E + I+ ++ SR A K S R + + A G S Q +
Sbjct: 1112 IKELQARIEELEEEIEA-ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKK 1170
Query: 814 QLAEEKK 820
+ AE +K
Sbjct: 1171 REAEFQK 1177
Score = 47.0 bits (110), Expect = 9e-05
Identities = 46/172 (26%), Positives = 87/172 (50%), Gaps = 18/172 (10%)
Query: 467 DKLHKFEKEL-QRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLH-DFNRD-----LR 519
++L + +K+L QR+ +A E + +K SL+K + +L+ E+ L D R
Sbjct: 1388 EELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKT-KQRLQNEVEDLMIDVERSNAACIAL 1446
Query: 520 DRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIE 579
D+ + ++ + + +E+ AE ASQ KE L EL V+ A E+ H+E
Sbjct: 1447 DKKQRNFDKVLAEWKQKYEETQAELE-ASQ-----KESRSLSTELFKVKNAYEESLDHLE 1500
Query: 580 ILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQAL----TQLQSACEKRE 627
L + N Q + L E++ E ++ ++EK+++ L ++LQ++ E+ E
Sbjct: 1501 TLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAE 1552
Score = 46.6 bits (109), Expect = 1e-04
Identities = 70/378 (18%), Positives = 144/378 (38%), Gaps = 60/378 (15%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
++ Q++ + L +E L E+ N + + K + +++ E + +E
Sbjct: 1211 IDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQ 1270
Query: 498 KAMRNKLEGEIRRLH----DFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEF 553
+ + N+L + RLH +F+R L D + QLS K A + K
Sbjct: 1271 QRLINELSAQKARLHTESGEFSRQL-DEKDAMVSQLS-------RGKQAFTQQIEELKRQ 1322
Query: 554 LKEKEKLEMELA-----------AVRTASEDHRRHIEILDQALSNAQARV---------- 592
L+E+ K + LA +R E+ + L + +S A + V
Sbjct: 1323 LEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETD 1382
Query: 593 -IKLEEELRE-KQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKH 650
I+ EEL E K+ ++++ ++ + + S C E+ ++R L+ E++ L +
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQR----LQNEVEDLMIDVER 1438
Query: 651 GNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKY------LEESTIRHFAMNA 704
N A L+ + +++LA +W+QKY LE S +++
Sbjct: 1439 SNA---------ACIALDKKQRNFDKVLA------EWKQKYEETQAELEASQKESRSLST 1483
Query: 705 AATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIE 764
++H +L+ I E++ + + ++E K L + E
Sbjct: 1484 ELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSE 1543
Query: 765 KDAMIKVLQQRSRKDAGK 782
++ + + GK
Sbjct: 1544 LQTSLEEAEASLEHEEGK 1561
Score = 45.1 bits (105), Expect = 3e-04
Identities = 77/427 (18%), Positives = 169/427 (39%), Gaps = 36/427 (8%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E ++MV ++ E+N L ++Q D + +L + E+ +K T+R ++
Sbjct: 876 ELEEKMVTLMQEKND-LQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEE 934
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKE 558
+ +L + R+L D +L+ ++ L+ E E H + + + +
Sbjct: 935 EINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIA 994
Query: 559 KLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQ 618
KL E A++ A + +++ + ++ KLE+++ + + +E+ +KL L +
Sbjct: 995 KLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLER 1054
Query: 619 LQSACE---------------KREQMERRLRTWLERELDALRTQQKHGNGQP-ANMPEYN 662
+ E ++Q+ +L+ ++E + Q K + Q A +
Sbjct: 1055 AKRKLEGDLKLAQESTMDTENDKQQLNEKLK---KKEFEMSNLQGKIEDEQALAIQLQKK 1111
Query: 663 APALLELVREKEERILALEADMTKWEQ------KYLEESTIRHFAMNAAATAAAERDTTI 716
L + E EE I A A K E+ + LEE + R A +A E
Sbjct: 1112 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE----- 1166
Query: 717 INHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRS 776
+N R + + + EE +Q + + A++ E+ ++ ++Q+
Sbjct: 1167 MNKKREAEFQKMRRDL-----EESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKL 1221
Query: 777 RKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKE 836
K+ + A ++ +++ A + QL+E K +E+ + I L ++
Sbjct: 1222 EKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQK 1281
Query: 837 HHEHASA 843
H +
Sbjct: 1282 ARLHTES 1288
Score = 40.8 bits (94), Expect = 0.006
Identities = 85/426 (19%), Positives = 172/426 (40%), Gaps = 72/426 (16%)
Query: 427 SQQLGPDAFAI---VERAQQMVEILTEENRVLHQEL----QGYYDNADKLHKFEKELQRI 479
S+ L + F + E + +E L EN+ L QE+ + + +H+ EK +++
Sbjct: 1478 SRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQL 1537
Query: 480 SEAYESLVKSTTKRE-SLD----KAMR-----NKLEGEI-RRLHDFNRDLRDRLETANRQ 528
L S + E SL+ K +R N+++ EI R++ + + +L R
Sbjct: 1538 DHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRV 1597
Query: 529 LSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNA 588
+ S + + + K+ + ++E++L + + R++ L +
Sbjct: 1598 VESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDT 1657
Query: 589 QARV---IKLEEELREKQAYVEKVEKLQQA-LTQLQSACEKREQMERRLRTWLERE-LDA 643
Q + I+ +++L+E+ A VE+ L QA + +L+++ E+ E R R E+E LDA
Sbjct: 1658 QLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTE----RGRKMAEQELLDA 1713
Query: 644 L-RTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAM 702
R Q H +L+ ++ E I ++ +M Q+ A+
Sbjct: 1714 SERVQLLHTQN----------TSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAI 1763
Query: 703 NAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKI 762
AA A E + +E++ R ++ME T+K+L ++
Sbjct: 1764 TDAAMMAEE----------------------LKKEQDTSAHLERMKKNMEQTVKDLQLRL 1801
Query: 763 IEKDAM--------IKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQ 814
E + + I+ L+ R R+ + +S +V + H R+ + Q
Sbjct: 1802 DEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLR----KHERRVKELTYQ 1857
Query: 815 LAEEKK 820
E++K
Sbjct: 1858 TEEDRK 1863
Score = 36.6 bits (83), Expect = 0.12
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 30/202 (14%)
Query: 443 QMVEILTEENRVLHQELQGYYDNADKLHKFEKE------LQRISEAYESLVKSTTKRESL 496
+M +I+ E + + D A + +KE L+R+ + E VK R L
Sbjct: 1744 EMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR--L 1801
Query: 497 DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKE 556
D+A + L+G +++ +LE R+L S E ++ + H N E +K
Sbjct: 1802 DEAEQLALKGGKKQIQ--------KLEARVRELES------EVESEQKH----NVEAVKG 1843
Query: 557 KEKLEMELAAVRTASEDHRRHIEILDQALSNAQARV--IKLEEELREKQAYVE--KVEKL 612
K E + + +E+ R++I L + Q +V K + E E+Q+ V K KL
Sbjct: 1844 LRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKL 1903
Query: 613 QQALTQLQSACEKREQMERRLR 634
Q L + + + E +LR
Sbjct: 1904 QHELEEAKERADIAESQVNKLR 1925
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 58.5 bits (140), Expect = 3e-08
Identities = 92/393 (23%), Positives = 170/393 (43%), Gaps = 80/393 (20%)
Query: 426 PSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYES 485
PS+ L D ER ++M E E++V H E+ + +H +EL R S+
Sbjct: 318 PSKSLEDDN----ERTRRMAEA---ESQVSHLEVILDQKEKENIH-LREELHRRSQLQPE 369
Query: 486 LVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGH 545
K+ KA++ +E + ++ R++RD LE + L + ED+ E
Sbjct: 370 PAKT--------KALQTVIEMKDTKIASLERNIRD-LEDEIQMLKANGVLNTEDREEEIK 420
Query: 546 ----YASQNKEFLKEK--------EKLEMELAAVRTASE-------DHRRHIEILDQALS 586
Y S +K F+K K K E EL A++T E D ++HIE+L ++L+
Sbjct: 421 QIEVYKSHSK-FMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLT 479
Query: 587 NAQARVIKLEEE-------LREKQAYVEKVEKLQQALT--------QLQSACEKREQMER 631
+ R L+ E L EK++++ K K Q LT +++ + E ER
Sbjct: 480 AKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKER 539
Query: 632 RLRTWLERELDALRTQQKHGNGQPANMPEY------------NAPALLELVREKEERIL- 678
++ L+++++ L+ Q + + Q N+ + A A LE ++ERI+
Sbjct: 540 KINV-LQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIE 598
Query: 679 ALEADMTKWEQKYLEESTIRHF---------AMNAAATAAAERDTTIIN---HSRNGSYG 726
L+ + +++ LEE I F +NA E+++++I+ H+ + +
Sbjct: 599 RLKEQRERDDRERLEE--IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASA 656
Query: 727 ESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLH 759
++ + E + Q C +E +K H
Sbjct: 657 GLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 689
Score = 37.4 bits (85), Expect = 0.067
Identities = 44/219 (20%), Positives = 89/219 (40%), Gaps = 14/219 (6%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
+E +M ++ + L +E Y D K + E+ R+ E + + ++ D
Sbjct: 691 IEDDSRMNPEFADQIKQLDKEASYYRDECGKA---QAEVDRLLEILKEV---ENEKNDKD 744
Query: 498 KAMRNKLEGEIRRLHDFNRDLRD-----RLETANRQLSSREYEGHEDKAAEGHYASQNKE 552
K + +R + D N+ + + +LE E ED A+ Q +E
Sbjct: 745 KKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEE 804
Query: 553 FLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELRE--KQAYVEKVE 610
+ EK EL A + ++ + + L+N + K EE+ E ++A + +
Sbjct: 805 LMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAIS 864
Query: 611 KLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQK 649
+ + L+ + K+++ + + L+RE D L Q K
Sbjct: 865 EKDANIALLELSASKKKKTQEEVMA-LKREKDRLVHQLK 902
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 58.2 bits (139), Expect = 4e-08
Identities = 73/320 (22%), Positives = 136/320 (42%), Gaps = 38/320 (11%)
Query: 466 ADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETA 525
ADK E ++ + + E L K + + N+L+ R+L + N LR +TA
Sbjct: 523 ADKKRNLENDVNSLKDQLEDL-KKRNQNSQISTEKVNQLQ---RQLDETNALLRTESDTA 578
Query: 526 NRQLSSREYEGHEDKAAEGHYAS-QNKEFLKE--KEKLEMELAAVRTASEDHRRHIEILD 582
R ++ + + E + Q+K L E K KLE E +++A E RR
Sbjct: 579 ARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGS 638
Query: 583 QALSNAQARVIKLEEELREKQAYVEKVE----KLQQALTQLQSACEKREQMERRLRTWLE 638
+ +++ Q R+ LEE+L+ + + KVE +LQ+ T L+ +++ ME + L+
Sbjct: 639 EIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLE---KEKSNMEIDMTYQLK 695
Query: 639 RELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIR 698
+L ++ A + + N + E + E A M + E+K LEE T++
Sbjct: 696 VIQQSLEQEEAEHKATKARLADKN--KIYESIEE------AKSEAMKEMEKKLLEERTLK 747
Query: 699 HFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNL 758
N A S L+ + Q ++++ + ++ + ++NL
Sbjct: 748 QKVENLLLEAEKRC---------------SLLDCDLKQSQQKINELLKQKDVLNEDVRNL 792
Query: 759 HAKIIEKDAMIKVLQQRSRK 778
K IE++ + L Q K
Sbjct: 793 TLK-IEQETQKRCLTQNDLK 811
Score = 43.1 bits (100), Expect = 0.001
Identities = 74/350 (21%), Positives = 146/350 (41%), Gaps = 47/350 (13%)
Query: 450 EENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIR 509
EE++ + ++L ++ + ++EL++ ++ + ++ T K + +R +E +R
Sbjct: 440 EESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALR 499
Query: 510 RLHDFNRDLRDR---------LETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEK--- 557
+L L+ + E ++ + +D+ + +QN + EK
Sbjct: 500 QLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQ 559
Query: 558 --EKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLE---EELREKQAYVEKVE-K 611
+L+ A +RT S+ R L + + + ++ +LE +L++K +E + K
Sbjct: 560 LQRQLDETNALLRTESDTAAR----LRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLK 615
Query: 612 LQQALTQLQSACEKREQMERRLRTW-------LERELDALRTQQKHGNGQPANMPEYNAP 664
L++ LQSA E ERR RT L+ + L K+G A + E
Sbjct: 616 LEKEFINLQSALES----ERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKV-ELEKR 670
Query: 665 ALLELVREKEERILALEADMT---KWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSR 721
L E + E+ +E DMT K Q+ LE+ H A A A+++ +
Sbjct: 671 QLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKA---RLADKNKIYESIEE 727
Query: 722 NGSYGESSLEAHIWQE-------EEEVVQANRRCQDMEYTIKNLHAKIIE 764
S +E + +E E +++A +RC ++ +K KI E
Sbjct: 728 AKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINE 777
Score = 32.3 bits (72), Expect = 2.2
Identities = 69/333 (20%), Positives = 129/333 (38%), Gaps = 64/333 (19%)
Query: 467 DKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETAN 526
++ + +K+L + E + +++ + E K++ +LE + L + LR +E+A
Sbjct: 440 EESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEE-EITLRKSVESAL 498
Query: 527 RQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALS 586
RQL RE + K AE Y + +K LE ++ +++ ED
Sbjct: 499 RQLE-REKALLQHKNAE--YQRKADHEADKKRNLENDVNSLKDQLED------------- 542
Query: 587 NAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRT 646
L++ + Q EKV +LQ+ L + + RLR + + +
Sbjct: 543 --------LKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRK--TQAESSKQI 592
Query: 647 QQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAA 706
QQ N R+ +++ LE K E++++ +A
Sbjct: 593 QQLESNN-----------------RDLQDKNCLLETAKLKLEKEFINLQ---------SA 626
Query: 707 TAAAERDTT----IINHSRNGSYG-ESSL---EAHIWQEEEEVVQANRRCQDMEYTIKNL 758
+ RD T IIN + G E L + + + E E Q R D+E N+
Sbjct: 627 LESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNM 686
Query: 759 HAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPA 791
I+ +KV+QQ ++ + ++ R A
Sbjct: 687 E---IDMTYQLKVIQQSLEQEEAEHKATKARLA 716
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 58.2 bits (139), Expect = 4e-08
Identities = 78/373 (20%), Positives = 152/373 (40%), Gaps = 53/373 (14%)
Query: 439 ERAQQMVEIL--TEENRVLHQELQGYYDNADKLHKFEKELQRISE--------------A 482
ER ++ + ++ TE R EL Y + ++LH E+E + +++
Sbjct: 170 ERKEESISLMKETEGKREKINELLKYIE--ERLHTLEEEKEELAQYQKWDKMRRALEYTI 227
Query: 483 YESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAA 542
Y + T + A R + R+L D +D RD++E RQ+ + + K
Sbjct: 228 YNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEE 287
Query: 543 EGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREK 602
+ +++ +E +K++ KLE++ ++ D+ N++ R + L+E+
Sbjct: 288 KEQLSAERQEQIKQRTKLELKAK-------------DLQDELAGNSEQR----KRLLKER 330
Query: 603 QAYVEKVEKLQQALTQLQSACEK-REQMERRLRTWLERELDALRTQQKHGNGQPANMPE- 660
Q +EK+E+ Q+ L + + +E+ ER + + + K G G E
Sbjct: 331 QKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEE 390
Query: 661 ------YNAPALLELVREKEERILALEADMTKWE---QKYLEESTIRHFAMNAAATAAAE 711
+L + + +K+ +I A+ D+ E +K LE+ +N E
Sbjct: 391 RDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVEE 450
Query: 712 RDTTIINHSRNGSYGESSLEAHIWQEEEEVVQA-NRRCQDMEYTIKNLHAKIIEK----- 765
D +N S ++W+EE QA + +D+E + L A +
Sbjct: 451 LDRKYY-EVKNKKDELQSERNYLWREENAEQQALAAKREDLEKKQQLLRAATGKAILNGI 509
Query: 766 DAMIKVLQQRSRK 778
D++ KVL RK
Sbjct: 510 DSINKVLDHFRRK 522
Score = 38.9 bits (89), Expect = 0.023
Identities = 72/304 (23%), Positives = 121/304 (39%), Gaps = 41/304 (13%)
Query: 440 RAQQMVEILTEENRVLHQELQ--GYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
RA M I E ++V H+ GYYD + +K++++ E L L+
Sbjct: 644 RAFTMDCITLEGDQVSHRGALTGGYYDTRKSRLELQKDVRKAEEELGEL------EAKLN 697
Query: 498 KAMRNKLEGEIRRLHDFNRDLRDRLETANRQL-SSREYEGHEDKAAEGHYASQNKEFLKE 556
+ +R +E I D + ++ET R+ +SR+ E K + K F+ +
Sbjct: 698 ENLRRNIE-RINNEIDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPK 756
Query: 557 K---EKLEMELAAVRTASEDHRRHI--EILDQALSNAQARVIKLEEELREKQAYVEKVEK 611
+ + LE L A+ + E + + ++L Q Q RV L +E+R+
Sbjct: 757 QRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQ---------- 806
Query: 612 LQQALTQLQSACEKREQMERRLRTWL-----------ERELDALRTQQKHGNGQPANMPE 660
LQQ QL + K E + R+ T+L E+EL+ LR + G
Sbjct: 807 LQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQELNELRETE---GGTVLTATT 863
Query: 661 YNAPALLELVREKEERILALEADMTKWEQ--KYLEESTIRHFAMNAAATAAAERDTTIIN 718
A+ + V++ R L+ + K E K L++S R M A DT +
Sbjct: 864 SELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAINHDTKELE 923
Query: 719 HSRN 722
N
Sbjct: 924 KMTN 927
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 58.2 bits (139), Expect = 4e-08
Identities = 101/418 (24%), Positives = 166/418 (39%), Gaps = 79/418 (18%)
Query: 451 ENRV--LHQELQGYYDNADKLHKFEKELQRISE-------AYESLVKSTTKRESLDKAMR 501
EN+V L +E+ G + KL K +K LQ + A E V + TK + +
Sbjct: 978 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV 1037
Query: 502 NKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQN-KEFLKEK-EK 559
+ LEG + + + LR LE A R+L EG A E +N K+ L EK +K
Sbjct: 1038 DDLEGSLEQ----EKKLRMDLERAKRKL-----EGDLKLAQESIMDIENEKQQLDEKLKK 1088
Query: 560 LEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQL 619
E E++ +++ ED + L + + QAR+ +LEEE+ ++A K EK
Sbjct: 1089 KEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK-------- 1140
Query: 620 QSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILA 679
R+ L REL+ + + + G + A +E+ +++E
Sbjct: 1141 -------------QRSDLSRELEEISERLEEAGGATS--------AQIEMNKKREAEFQK 1179
Query: 680 LEADMTKWEQKYLEESTIRHFAMNAA-----ATAAAERDTTIINHSR-----NGSYGESS 729
+ D LEE+T++H A A A + AE I N R E
Sbjct: 1180 MRRD--------LEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1231
Query: 730 LEAHIWQEEEEVV-----QANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTD 784
+E E V + C+ +E + L +K E+ +I L + G+
Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ----RGRLQ 1287
Query: 785 SSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKK---EEKTWKGSIGLLLGKEHHE 839
+ S +R + A SR + Q+ E K+ EE K ++ L H+
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345
Score = 53.9 bits (128), Expect = 7e-07
Identities = 80/414 (19%), Positives = 172/414 (41%), Gaps = 50/414 (12%)
Query: 439 ERAQQMVEILTEENRVLHQ---ELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
E ++MV +L E+N + Q E +G D ++ + K ++ E+ +K T+R
Sbjct: 878 ELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQL----EAKIKEVTERAE 933
Query: 496 LDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLK 555
++ + +L + R+L D +L+ ++ L+ E E H + + + +
Sbjct: 934 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 993
Query: 556 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA 615
KL E A++ A + ++ + ++ IKLE+++ + + +E+ +KL+
Sbjct: 994 TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMD 1053
Query: 616 LTQLQSACE---------------KREQMERRLRTWLERELDALRTQQKHGNGQPANMP- 659
L + + E +++Q++ +L+ ++E + Q K + Q +
Sbjct: 1054 LERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK---KKEFEISNLQSKIEDEQALGIQL 1110
Query: 660 EYNAPALLELVREKEERILALEADMTKWEQ------KYLEESTIRHFAMNAAATAAAERD 713
+ L + E EE I A A K E+ + LEE + R A +A E
Sbjct: 1111 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE-- 1168
Query: 714 TTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKII----EKDAMI 769
+N R EA + ++ +A + + T++ HA + E+ +
Sbjct: 1169 ---MNKKR---------EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNL 1216
Query: 770 KVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEK 823
+ ++Q+ K+ + A +V +++ A G + QL+E K +E+
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEE 1270
Score = 47.8 bits (112), Expect = 5e-05
Identities = 80/412 (19%), Positives = 166/412 (40%), Gaps = 44/412 (10%)
Query: 427 SQQLGPDAFAI---VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAY 483
++ LG + F I E + +E L EN+ L QE+ + + K EL++I +
Sbjct: 1480 ARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQV 1539
Query: 484 ESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAE 543
E + + +L++A LE E ++ +L +R+++ ++ E + K
Sbjct: 1540 EQ--EKCELQAALEEA-EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNH 1596
Query: 544 GHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQ 603
+ L + + + ++ E +EI L++A + R Q
Sbjct: 1597 IRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI---QLNHANRMAAEALRNYRNTQ 1653
Query: 604 AYVEKVE-KLQQALTQLQSACEKREQMERRLRTWLERELDALRT--QQKHGNGQPANMPE 660
++ + L AL + E+ +ERR L+ E++ LR +Q + + A
Sbjct: 1654 GILKDTQIHLDDALRSQEDLKEQLAMVERRANL-LQAEIEELRATLEQTERSRKIAEQEL 1712
Query: 661 YNAPALLELVREKEERIL----ALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI 716
+A ++L+ + ++ LE D+++ + E I A NA A
Sbjct: 1713 LDASERVQLLHTQNTSLINTKKKLETDISQMQG---EMEDILQEARNAEEKA-------- 1761
Query: 717 INHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAM-------- 768
+ + + + +E++ R ++ME T+K+L ++ E + +
Sbjct: 1762 ----KKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQ 1817
Query: 769 IKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKK 820
I+ L+ R R+ G+ +S R A +V + H R+ + Q E++K
Sbjct: 1818 IQKLEARVRELEGEVESEQKRNAEAVKGLR----KHERRVKELTYQTEEDRK 1865
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/329 (19%), Positives = 132/329 (40%), Gaps = 32/329 (9%)
Query: 448 LTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGE 507
L NR+ + L+ Y + L + L + E L + E N L+ E
Sbjct: 1635 LNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER----RANLLQAE 1690
Query: 508 IRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAV 567
I +LR LE R E E + +QN + K+KLE +++ +
Sbjct: 1691 IE-------ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
Query: 568 RTASEDHRRHIEILDQALSNAQARVIKLEEELREKQ---AYVEKVEK-LQQALTQLQSAC 623
+ ED + ++ A + EEL+++Q A++E+++K ++Q + LQ
Sbjct: 1744 QGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Query: 624 EKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEAD 683
++ EQ+ + ++++ L + + G+ + + NA A+ L R+ E R+ L
Sbjct: 1804 DEAEQLALK---GGKKQIQKLEARVRELEGEVESEQKRNAEAVKGL-RKHERRVKELTYQ 1859
Query: 684 MTKWE------QKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQE 737
+ Q +++ + + A A E+ T + R L+ + +
Sbjct: 1860 TEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFR-------KLQHELEEA 1912
Query: 738 EEEVVQANRRCQDMEYTIKNLHAKIIEKD 766
EE A + + + +H K+I ++
Sbjct: 1913 EERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 38.9 bits (89), Expect = 0.023
Identities = 74/374 (19%), Positives = 140/374 (37%), Gaps = 58/374 (15%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E Q+++ LT + L E + D+ +L R +A+ ++ ++ +
Sbjct: 1270 EEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEI 1329
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETAN-------RQLSSREYEGHEDKAAEGHYASQNK 551
+N L ++ LR++ E R LS E + + A Q
Sbjct: 1330 KAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRT 1389
Query: 552 EFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVE---- 607
E L+E +K +LA A+E+H +E ++ ++ + +L+ E+ + VE
Sbjct: 1390 EELEEAKK---KLAQRLQAAEEH---VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
Query: 608 -------KVEKLQQALTQLQSACE------KREQMERR--------LRTWLERELDALRT 646
K + L + + CE + Q E R ++ E LD L T
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 647 QQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAA 706
++ + + L E + E +RI LE + EQ+ E A+ A
Sbjct: 1504 LKRENKNLQQEISD-----LTEQIAEGGKRIHELEKIKKQVEQEKCELQA----ALEEAE 1554
Query: 707 TAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKD 766
+ + I+ + +S ++ I +++EE+ Q +K H +I+E
Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ-----------LKRNHIRIVESM 1603
Query: 767 AMIKVLQQRSRKDA 780
+ RSR DA
Sbjct: 1604 QSTLDAEIRSRNDA 1617
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 58.2 bits (139), Expect = 4e-08
Identities = 101/418 (24%), Positives = 166/418 (39%), Gaps = 79/418 (18%)
Query: 451 ENRV--LHQELQGYYDNADKLHKFEKELQRISE-------AYESLVKSTTKRESLDKAMR 501
EN+V L +E+ G + KL K +K LQ + A E V + TK + +
Sbjct: 978 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV 1037
Query: 502 NKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQN-KEFLKEK-EK 559
+ LEG + + + LR LE A R+L EG A E +N K+ L EK +K
Sbjct: 1038 DDLEGSLEQ----EKKLRMDLERAKRKL-----EGDLKLAQESIMDIENEKQQLDEKLKK 1088
Query: 560 LEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQL 619
E E++ +++ ED + L + + QAR+ +LEEE+ ++A K EK
Sbjct: 1089 KEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK-------- 1140
Query: 620 QSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILA 679
R+ L REL+ + + + G + A +E+ +++E
Sbjct: 1141 -------------QRSDLSRELEEISERLEEAGGATS--------AQIEMNKKREAEFQK 1179
Query: 680 LEADMTKWEQKYLEESTIRHFAMNAA-----ATAAAERDTTIINHSR-----NGSYGESS 729
+ D LEE+T++H A A A + AE I N R E
Sbjct: 1180 MRRD--------LEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1231
Query: 730 LEAHIWQEEEEVV-----QANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTD 784
+E E V + C+ +E + L +K E+ +I L + G+
Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ----RGRLQ 1287
Query: 785 SSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKK---EEKTWKGSIGLLLGKEHHE 839
+ S +R + A SR + Q+ E K+ EE K ++ L H+
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345
Score = 53.9 bits (128), Expect = 7e-07
Identities = 80/414 (19%), Positives = 172/414 (41%), Gaps = 50/414 (12%)
Query: 439 ERAQQMVEILTEENRVLHQ---ELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
E ++MV +L E+N + Q E +G D ++ + K ++ E+ +K T+R
Sbjct: 878 ELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQL----EAKIKEVTERAE 933
Query: 496 LDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLK 555
++ + +L + R+L D +L+ ++ L+ E E H + + + +
Sbjct: 934 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 993
Query: 556 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA 615
KL E A++ A + ++ + ++ IKLE+++ + + +E+ +KL+
Sbjct: 994 TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMD 1053
Query: 616 LTQLQSACE---------------KREQMERRLRTWLERELDALRTQQKHGNGQPANMP- 659
L + + E +++Q++ +L+ ++E + Q K + Q +
Sbjct: 1054 LERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK---KKEFEISNLQSKIEDEQALGIQL 1110
Query: 660 EYNAPALLELVREKEERILALEADMTKWEQ------KYLEESTIRHFAMNAAATAAAERD 713
+ L + E EE I A A K E+ + LEE + R A +A E
Sbjct: 1111 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE-- 1168
Query: 714 TTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKII----EKDAMI 769
+N R EA + ++ +A + + T++ HA + E+ +
Sbjct: 1169 ---MNKKR---------EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNL 1216
Query: 770 KVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEK 823
+ ++Q+ K+ + A +V +++ A G + QL+E K +E+
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEE 1270
Score = 47.8 bits (112), Expect = 5e-05
Identities = 80/412 (19%), Positives = 166/412 (40%), Gaps = 44/412 (10%)
Query: 427 SQQLGPDAFAI---VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAY 483
++ LG + F I E + +E L EN+ L QE+ + + K EL++I +
Sbjct: 1480 ARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQV 1539
Query: 484 ESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAE 543
E + + +L++A LE E ++ +L +R+++ ++ E + K
Sbjct: 1540 EQ--EKCELQAALEEA-EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNH 1596
Query: 544 GHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQ 603
+ L + + + ++ E +EI L++A + R Q
Sbjct: 1597 IRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI---QLNHANRMAAEALRNYRNTQ 1653
Query: 604 AYVEKVE-KLQQALTQLQSACEKREQMERRLRTWLERELDALRT--QQKHGNGQPANMPE 660
++ + L AL + E+ +ERR L+ E++ LR +Q + + A
Sbjct: 1654 GILKDTQIHLDDALRSQEDLKEQLAMVERRANL-LQAEIEELRATLEQTERSRKIAEQEL 1712
Query: 661 YNAPALLELVREKEERIL----ALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI 716
+A ++L+ + ++ LE D+++ + E I A NA A
Sbjct: 1713 LDASERVQLLHTQNTSLINTKKKLETDISQMQG---EMEDILQEARNAEEKA-------- 1761
Query: 717 INHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAM-------- 768
+ + + + +E++ R ++ME T+K+L ++ E + +
Sbjct: 1762 ----KKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQ 1817
Query: 769 IKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKK 820
I+ L+ R R+ G+ +S R A +V + H R+ + Q E++K
Sbjct: 1818 IQKLEARVRELEGEVESEQKRNAEAVKGLR----KHERRVKELTYQTEEDRK 1865
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/329 (19%), Positives = 132/329 (40%), Gaps = 32/329 (9%)
Query: 448 LTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGE 507
L NR+ + L+ Y + L + L + E L + E N L+ E
Sbjct: 1635 LNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER----RANLLQAE 1690
Query: 508 IRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAV 567
I +LR LE R E E + +QN + K+KLE +++ +
Sbjct: 1691 IE-------ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
Query: 568 RTASEDHRRHIEILDQALSNAQARVIKLEEELREKQ---AYVEKVEK-LQQALTQLQSAC 623
+ ED + ++ A + EEL+++Q A++E+++K ++Q + LQ
Sbjct: 1744 QGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Query: 624 EKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEAD 683
++ EQ+ + ++++ L + + G+ + + NA A+ L R+ E R+ L
Sbjct: 1804 DEAEQLALK---GGKKQIQKLEARVRELEGEVESEQKRNAEAVKGL-RKHERRVKELTYQ 1859
Query: 684 MTKWE------QKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQE 737
+ Q +++ + + A A E+ T + R L+ + +
Sbjct: 1860 TEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFR-------KLQHELEEA 1912
Query: 738 EEEVVQANRRCQDMEYTIKNLHAKIIEKD 766
EE A + + + +H K+I ++
Sbjct: 1913 EERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 38.9 bits (89), Expect = 0.023
Identities = 74/374 (19%), Positives = 140/374 (37%), Gaps = 58/374 (15%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E Q+++ LT + L E + D+ +L R +A+ ++ ++ +
Sbjct: 1270 EEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEI 1329
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETAN-------RQLSSREYEGHEDKAAEGHYASQNK 551
+N L ++ LR++ E R LS E + + A Q
Sbjct: 1330 KAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRT 1389
Query: 552 EFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVE---- 607
E L+E +K +LA A+E+H +E ++ ++ + +L+ E+ + VE
Sbjct: 1390 EELEEAKK---KLAQRLQAAEEH---VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
Query: 608 -------KVEKLQQALTQLQSACE------KREQMERR--------LRTWLERELDALRT 646
K + L + + CE + Q E R ++ E LD L T
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 647 QQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAA 706
++ + + L E + E +RI LE + EQ+ E A+ A
Sbjct: 1504 LKRENKNLQQEISD-----LTEQIAEGGKRIHELEKIKKQVEQEKCELQA----ALEEAE 1554
Query: 707 TAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKD 766
+ + I+ + +S ++ I +++EE+ Q +K H +I+E
Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ-----------LKRNHIRIVESM 1603
Query: 767 AMIKVLQQRSRKDA 780
+ RSR DA
Sbjct: 1604 QSTLDAEIRSRNDA 1617
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 57.8 bits (138), Expect = 5e-08
Identities = 75/360 (20%), Positives = 152/360 (42%), Gaps = 40/360 (11%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
+++A +++ H++ + Y ++L + +++L + L K + E+
Sbjct: 793 LQQASAKLDVFQSYQSATHEQTKAY---EEQLAQLQQKLLDLETERILLTKQVAEVEAQK 849
Query: 498 KAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYAS-QNKEFLKE 556
K + +L+ ++ D + L + +++ S + +E K +G+ Q K+ L E
Sbjct: 850 KDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLT-QVYESKLEDGNKEQEQTKQILVE 908
Query: 557 KEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREK-QAYVEKVEKLQQA 615
KE + +++ E ++ IEIL Q LS + + L EE K + +K+EK++Q
Sbjct: 909 KENMILQMR------EGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQK 962
Query: 616 LTQLQSACEKR-EQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKE 674
++Q +K+ E +L+ LE L ++K N + M + N+ + + V E
Sbjct: 963 AKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLE 1022
Query: 675 ----ERILA--------LEADMTKWEQKYLEES----TIRHFAMNAAATAAAERDTTIIN 718
E+I + L ++ WE+K +++ I + AE I+
Sbjct: 1023 TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILL 1082
Query: 719 HSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRK 778
G E + W +EE V Q + T+ L ++ +K A + L Q K
Sbjct: 1083 F---GCEKEEMNKEITWLKEEGVKQ--------DTTLNELQEQLKQKSAHVNSLAQDETK 1131
Score = 51.6 bits (122), Expect = 3e-06
Identities = 93/444 (20%), Positives = 185/444 (41%), Gaps = 83/444 (18%)
Query: 428 QQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLV 487
Q+LG + V+ A++ +ILT EN+V Y +L +KEL+ ++ + +S
Sbjct: 1570 QELGEEKDNRVKEAEE--KILTLENQV--------YSMKAELETKKKELEHVNLSVKS-- 1617
Query: 488 KSTTKRESLDKAMRNKLEGE-IRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHY 546
K E L KA+ ++LE E +L + R ++ +QL S+ E E
Sbjct: 1618 ----KEEEL-KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEE-------- 1664
Query: 547 ASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQAL---SNAQARVIKLEEELREKQ 603
+ K+ E L+ + T ++ R + IL++ L ++Q+ + + +
Sbjct: 1665 --------QYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVA 1716
Query: 604 AYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNA 663
AY E+ E Q Q ++ EK ++R L E+E R Q+ E
Sbjct: 1717 AYTEQEEADSQGCVQ-KTYEEKISVLQRNL---TEKEKLLQRVGQE---------KEETV 1763
Query: 664 PALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNG 723
+ E+ + +ER++ LE K ++ ++S I H + ++ + I+
Sbjct: 1764 SSHFEMRCQYQERLIKLEHAEAK---QHEDQSMIGH--LQEELEEKNKKYSLIVAQHVEK 1818
Query: 724 SYGESSLEA-----HIWQEEEEVVQANR-RCQDMEYTIKNLHAKIIEKDAMIKVLQQRSR 777
G+++++A +++ + ++ +Q CQ +E IK L + ++ + + +V +
Sbjct: 1819 EGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELT 1878
Query: 778 KDAGKTDSSSLRPARSVPSIAAATGT------HSRQTSLTSSQLAE-----------EKK 820
K + R+ P+ T H Q L S+ A+ E++
Sbjct: 1879 SKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAERE 1938
Query: 821 EEKTWKGSIGL-----LLGKEHHE 839
++K K + L +L KEH +
Sbjct: 1939 KQKLGKEIVRLQKDLRMLRKEHQQ 1962
Score = 45.8 bits (107), Expect = 2e-04
Identities = 61/295 (20%), Positives = 128/295 (43%), Gaps = 28/295 (9%)
Query: 434 AFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEK-----ELQRISEAYESLVK 488
AF +E+A + E R L E+ +K + E+ EL R+ + ++K
Sbjct: 412 AFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMK 471
Query: 489 STTKRESLDKAMRNKL-EGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYA 547
+++ + A KL E E+ R ++L +L+T R+ + E +E
Sbjct: 472 KSSEEQI---AKLQKLHEKELARKE---QELTKKLQTREREFQEQMKVALEKSQSEYLKI 525
Query: 548 SQNKEFLKE--KEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAY 605
SQ KE + E+LE++ A+ T SE+ R L Q + R+++LE L +++
Sbjct: 526 SQEKEQQESLALEELELQKKAILTESENKLRD---LQQEAETYRTRILELESSL--EKSL 580
Query: 606 VEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPA 665
E + + L++ K + + + EL++L+ QQ + + +
Sbjct: 581 QENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQT 640
Query: 666 LLELVREK---------EERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAE 711
+E +REK +++ + +A + + +K LE+ ++ + + ++ +E
Sbjct: 641 EMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE 695
Score = 45.4 bits (106), Expect = 2e-04
Identities = 91/444 (20%), Positives = 178/444 (40%), Gaps = 69/444 (15%)
Query: 428 QQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLV 487
QQ + + E+ +Q E L ++ ++ Q + ++++ EK L+++ L
Sbjct: 636 QQYQTEMEKLREKCEQEKETLLKDKEIIFQA------HIEEMN--EKTLEKLDVKQTELE 687
Query: 488 KSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYA 547
+++ + KA R+KLE E+ L D ++ LE A ++ D + H
Sbjct: 688 SLSSELSEVLKA-RHKLEEELSVLKDQTDKMKQELE-AKMDEQKNHHQQQVDSIIKEHEV 745
Query: 548 S--QNKEFLKEK-EKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQA 604
S + ++ LK++ +LE+ L ++H+ H+E N +A + + E EL++ A
Sbjct: 746 SIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE-------NLEADIKRSEGELQQASA 798
Query: 605 YVEKVEKLQQALTQLQSACEKR-EQMERRLRTWLERELDALRTQQKHGNGQPANM-PEYN 662
++ + Q A + A E++ Q++++L LE E L Q Q ++ E +
Sbjct: 799 KLDVFQSYQSATHEQTKAYEEQLAQLQQKLLD-LETERILLTKQVAEVEAQKKDVCTELD 857
Query: 663 APAL--LELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS 720
A + +L+++ E++ +E + Q Y + + E++ I+
Sbjct: 858 AHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMIL-QM 916
Query: 721 RNGSYGESSL----------EAHIWQEEEE---------VVQANRRCQDMEYTIKN---- 757
R G E + HI EE E + + ++ ++M+ T+K
Sbjct: 917 REGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLD 976
Query: 758 -------------LHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTH 804
L EK K+L+ AG +D+ S I + T H
Sbjct: 977 QEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVH 1036
Query: 805 SRQTSLTSS-------QLAEEKKE 821
R+ + S Q AEE +E
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQE 1060
Score = 42.0 bits (97), Expect = 0.003
Identities = 72/367 (19%), Positives = 152/367 (41%), Gaps = 61/367 (16%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
V +Q + + E +++E+ + K ELQ + + V S + E+
Sbjct: 1073 VAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKL 1132
Query: 498 KAMRNKLEGEIRRLHDFNRDLRDRLE----------------TANRQLSSREYEGHEDKA 541
KA KLE ++ + N L+++L T+ + + E++ +
Sbjct: 1133 KAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSH 1192
Query: 542 AEGHYASQNK--EFLKEKEKL--EMELAAVRTASEDHRRHIEILD----------QALSN 587
+ + + ++K EF K E+L ++++ +T + + E+++ +S+
Sbjct: 1193 EKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISH 1252
Query: 588 AQARVIKLEEELREKQAYVEKVEKLQQALTQ--------LQSACEKREQMERRLRTWLER 639
Q R K++E L K V ++E + LT+ Q A + E+ E ++++ ++
Sbjct: 1253 CQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKS-MKA 1311
Query: 640 ELDALRTQ----QKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEES 695
++++L T+ QK G Q E + + +L +E E I A+ + ++K +E S
Sbjct: 1312 DIESLVTEKEALQKEGGNQQQAASEKES-CITQLKKELSENINAVTLMKEELKEKKVEIS 1370
Query: 696 TIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHI----WQEEEEVVQANRRCQDM 751
++ + T +N S S EA I Q +EE + + QD+
Sbjct: 1371 SL-------------SKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDL 1417
Query: 752 EYTIKNL 758
+ + L
Sbjct: 1418 SFKVDTL 1424
Score = 39.7 bits (91), Expect = 0.014
Identities = 58/251 (23%), Positives = 107/251 (42%), Gaps = 30/251 (11%)
Query: 457 QELQGYYDNADKLHKFEKEL------QRISEAYESLVKS-----------TTKRESLDKA 499
Q L+ +D+ K + EKEL Q+I E LV+ T+K E L
Sbjct: 1829 QNLENVFDDVQKTLQ-EKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQAL 1887
Query: 500 MRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFL-KEKE 558
+ + L + N + + + +L S H D + A + K+ L KE
Sbjct: 1888 QQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIV 1947
Query: 559 KLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQ 618
+L+ +L +R ++H++ +EIL + + IK E+E E + + +++ TQ
Sbjct: 1948 RLQKDLRMLR---KEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQ 2004
Query: 619 LQSACEKREQMERRLRTWL----ERELDALRTQQKHGNGQPANMPEYNAPALLELVREKE 674
L +K +++E ++ + E E + L + Q+ N + E + L + E
Sbjct: 2005 L---AQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKD-DDLKRTAKRYE 2060
Query: 675 ERILALEADMT 685
E + A E +MT
Sbjct: 2061 EILDAREEEMT 2071
Score = 39.3 bits (90), Expect = 0.018
Identities = 45/193 (23%), Positives = 82/193 (42%), Gaps = 21/193 (10%)
Query: 502 NKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLE 561
++LE ++R+L + L + A QL +E + KA + + EKE L+
Sbjct: 1272 SELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKA-------DIESLVTEKEALQ 1324
Query: 562 MELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEK-LQQALTQLQ 620
E + A+ + I L + LS V ++EEL+EK+ + + K L QLQ
Sbjct: 1325 KEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQ 1384
Query: 621 SACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILAL 680
++ E+ E + +LR Q + + + + ++ +E+I AL
Sbjct: 1385 NSISLSEK---------EAAISSLRKQY---DEEKCELLDQVQDLSFKVDTLSKEKISAL 1432
Query: 681 EADMTKWEQKYLE 693
E + W K+ E
Sbjct: 1433 E-QVDDWSNKFSE 1444
Score = 36.6 bits (83), Expect = 0.12
Identities = 60/315 (19%), Positives = 127/315 (40%), Gaps = 26/315 (8%)
Query: 538 EDKAAEGHYASQNKEFLKEK-EKLEMELAAVRTASEDHRRHIEI----LDQALSNAQARV 592
E K+ E + + LKE+ ++ ++ ED + +E L+ L + AR+
Sbjct: 1468 ELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARI 1527
Query: 593 IKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGN 652
++LE+ + +K +E + ++ + Q Q E +E +++ E R ++
Sbjct: 1528 MELEDHITQKTIEIESLNEVLKNYNQ-QKDIEHKELVQKLQHFQELGEEKDNRVKEAEEK 1586
Query: 653 GQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAER 712
Y+ A LE ++KE + L + E K LE+ +E
Sbjct: 1587 ILTLENQVYSMKAELE-TKKKELEHVNLSVKSKEEELKALED------------RLESES 1633
Query: 713 DTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVL 772
+ R ++++ + + EE + ++ E + L+ K+ E++ + +L
Sbjct: 1634 AAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKK--GTESHLSELNTKLQEREREVHIL 1691
Query: 773 QQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEK----KEEKTWKGS 828
+++ K + S +L RS ++AA T + + EEK + T K
Sbjct: 1692 EEK-LKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEK 1750
Query: 829 IGLLLGKEHHEHASA 843
+ +G+E E S+
Sbjct: 1751 LLQRVGQEKEETVSS 1765
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 57.4 bits (137), Expect = 6e-08
Identities = 81/386 (20%), Positives = 164/386 (42%), Gaps = 42/386 (10%)
Query: 427 SQQLGPDAFAIVERAQQMVEILTEENRV--LHQELQGYYDNADKLHKFEKEL-QRISEAY 483
SQQL ++ ++M E+ + N + L EL+ + + EL Q+++E Y
Sbjct: 1133 SQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENY 1192
Query: 484 ESLVKSTTKRESLDKAM-------RNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEG 536
E VKS TK + K + R+ L G IR + ++ L+ A+ L +
Sbjct: 1193 EE-VKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETI 1251
Query: 537 HEDKAAEGHYASQ---NKEFLKEKEKLEMELAAVRTASE------------DHRRHIEIL 581
E + + +Q ++ K KL+ E+ + E + +E+L
Sbjct: 1252 DELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELL 1311
Query: 582 DQ--------ALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACE-KREQMERR 632
+ L+ + ++L E+ +E Q ++ + K + L ++ A E K +Q++
Sbjct: 1312 TEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEH 1371
Query: 633 LRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYL 692
+R L + ++ Q++ N + + + +E + K+ +L +E +M ++ L
Sbjct: 1372 IRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKR-L 1430
Query: 693 EESTIRHFAMNAAATAAAE-RDTTIINHSRNGSYGESSLE--AHIWQEEEEVVQANRRCQ 749
+ES H M + A + + + S + E+ E A + EEE+ A+ +
Sbjct: 1431 QES---HDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLK 1487
Query: 750 DMEYTIKNLHAKIIEKDAMIKVLQQR 775
+ E TI L + EK+ I +Q++
Sbjct: 1488 EQEETINELRVNLSEKETEISTIQKQ 1513
Score = 42.4 bits (98), Expect = 0.002
Identities = 53/274 (19%), Positives = 117/274 (42%), Gaps = 33/274 (12%)
Query: 450 EENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIR 509
EEN L +E+ + + E+ + I + E L T++++ L + +K E ++
Sbjct: 734 EENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHK-ESRVQ 792
Query: 510 RLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEME------ 563
L + +D L T S + E K + + K L+E E++ E
Sbjct: 793 GLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSK 852
Query: 564 --------LAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKV------ 609
L A++T + ++ + + + +L+E+L + + ++ V
Sbjct: 853 EAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTL 912
Query: 610 --EKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANM---PEYNAP 664
EKLQQ L ++++ ++++ +++ L+ L R Q K NM +
Sbjct: 913 ITEKLQQTLEEVKTLTQEKDDLKQ-----LQESLQIERDQLKSDIHDTVNMNIDTQEQLR 967
Query: 665 ALLELVREKEERILALEADMTKWEQK--YLEEST 696
LE +++ +E I L++ +++ + ++EE+T
Sbjct: 968 NALESLKQHQETINTLKSKISEEVSRNLHMEENT 1001
Score = 39.3 bits (90), Expect = 0.018
Identities = 53/255 (20%), Positives = 115/255 (45%), Gaps = 29/255 (11%)
Query: 455 LHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDF 514
L + LQ +D + K + +LQR+ E +S +S +E++ + + LE E L
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDLQRLQEVLQS--ESDQLKENIKEIVAKHLETE-EELKVA 1482
Query: 515 NRDLRDRLETANR---QLSSREYE----GHEDKAAEGHYASQNKEFLKEKEKLEM----E 563
+ L+++ ET N LS +E E + +A ++ +E +++E+ + E
Sbjct: 1483 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1542
Query: 564 LAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSAC 623
+ + + H + D AL + ++++++L +LQ++ ++Q
Sbjct: 1543 VQEKVNELKQFKEHRKAKDSALQSIESKMLEL-------------TNRLQESQEEIQIMI 1589
Query: 624 EKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPAL-LELVREKEERILALEA 682
+++E+M +R++ L+ E D L+ K + E L + V E +E++ +E
Sbjct: 1590 KEKEEM-KRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEH 1648
Query: 683 DMTKWEQKYLEESTI 697
++E + L I
Sbjct: 1649 LKEQFETQKLNLENI 1663
Score = 35.0 bits (79), Expect = 0.33
Identities = 68/314 (21%), Positives = 132/314 (42%), Gaps = 49/314 (15%)
Query: 471 KFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDR--LETANRQ 528
K +E+ R E+ ++ + + + K + E + D++D +E +
Sbjct: 986 KISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKI 1045
Query: 529 LSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELA---AVRTASEDHRRHIEILDQA- 584
S + + + E A + + KE +EM + +R ++ ++ EI+ Q
Sbjct: 1046 FSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEK 1105
Query: 585 ---------LSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRT 635
LS R+ ++EE+L+EK ++LQ+ QL + E+ +M++++
Sbjct: 1106 NHAIKKEGELSRTCDRLAEVEEKLKEKS------QQLQEKQQQLLNVQEEMSEMQKKI-- 1157
Query: 636 WLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEES 695
E++ L+ + K+ +M E L + + E E + ++ TK E+K L+E
Sbjct: 1158 ---NEIENLKNELKNKELTLEHM-ETERLELAQKLNENYEEVKSI----TK-ERKVLKE- 1207
Query: 696 TIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTI 755
+ ERD H R G E +EA Q +EE+ A+ ++ + TI
Sbjct: 1208 --------LQKSFETERD-----HLR-GYIRE--IEATGLQTKEELKIAHIHLKEHQETI 1251
Query: 756 KNLHAKIIEKDAMI 769
L + EK A I
Sbjct: 1252 DELRRSVSEKTAQI 1265
Score = 34.3 bits (77), Expect = 0.57
Identities = 47/220 (21%), Positives = 102/220 (46%), Gaps = 18/220 (8%)
Query: 445 VEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESL-VKSTTKRESLDKAMRNK 503
+E + EN L Q L ++N +++ KE + E+L V+ +E+L + +
Sbjct: 1660 LENIETENIRLTQIL---HENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRD 1716
Query: 504 LEG--EIRRLHDFNRDLRDRLETANRQLSSREYE-GHEDKAAEGHYASQNKEFLKEKEKL 560
LE E++ +H ++ ++ ++ +S + E + K E + + LK +E+L
Sbjct: 1717 LEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEEL 1776
Query: 561 E---MELAAVRTASEDHRRHIEILDQALSNAQARV----IKLEEELREKQAYVEKVEKLQ 613
M L + + R + LSN Q + KL+E+++E +A ++ L+
Sbjct: 1777 RIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLK 1836
Query: 614 QALTQLQSACEKREQMERRLR----TWLERELDALRTQQK 649
+ + + Q + EQ++++++ T + E++ L QK
Sbjct: 1837 KDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQK 1876
Score = 33.5 bits (75), Expect = 0.97
Identities = 26/102 (25%), Positives = 53/102 (51%), Gaps = 8/102 (7%)
Query: 552 EFLKEKEKLEMELAAVRTAS--EDHRRHIEILDQALSNAQARVIKL----EEELREKQAY 605
E L+ K K + E+ + S ++ +H E+ +Q L N + ++L E+++++ Q Y
Sbjct: 538 EALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEY 597
Query: 606 V--EKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALR 645
+ +K+E ++ L+ + E +QM++ L LDA R
Sbjct: 598 IDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKR 639
Score = 30.4 bits (67), Expect = 8.2
Identities = 44/238 (18%), Positives = 89/238 (37%), Gaps = 49/238 (20%)
Query: 437 IVERAQQMV-EILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLV-------K 488
+ RA Q+ E + E LH+ + K+ K +KEL+ ++ L K
Sbjct: 2371 VTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNK 2430
Query: 489 STTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETAN--RQLSSREYEGHEDKAAEGHY 546
K + + +++K+ + + DL+ +L + + +++E+E
Sbjct: 2431 CLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFE----------- 2479
Query: 547 ASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQA---------------------- 584
KE K +E + +R E+ RR + D +
Sbjct: 2480 ----KEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSG 2535
Query: 585 -LSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLEREL 641
+ N +A ++K E EK+ K ++ +Q + Q + + ++TW ER L
Sbjct: 2536 IVQNTKALILKSEHIRLEKEISKLK-QQNEQLIKQKNELLSNNQHLSNEVKTWKERTL 2592
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 57.4 bits (137), Expect = 6e-08
Identities = 78/382 (20%), Positives = 158/382 (41%), Gaps = 44/382 (11%)
Query: 438 VERAQQMVEILTEENRVLHQEL----QGYYDNADKLHKFEKELQRISEAYESLVKS---- 489
V + QQ ++ L + LH ++ Q + + ++ ++EL + + + +L K
Sbjct: 1831 VRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD-HLNLAKQDLLH 1889
Query: 490 TTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQ 549
TTK + + + + +L+ +I + D + ET +QL + E E+K
Sbjct: 1890 TTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMM 1949
Query: 550 NKEFLKEKEKLE--MELAAVRTASEDHRRHIEILDQ--ALSNAQARVIKLEEELREKQAY 605
+ KE+E E +E + V + H+ E+ DQ L ++V+ EE +R Q
Sbjct: 1950 FQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEE 2009
Query: 606 VEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPA 665
E L++ L+Q + +REQ L + L QK + A+
Sbjct: 2010 ERWCESLEKTLSQTKRQLSEREQQ-------LVEKSGELLALQKEADSMRADFSLLRNQF 2062
Query: 666 LLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNA-----------AATAAAERDT 714
L E R+K E+ +A + K ++ LE++ + N+ A ER
Sbjct: 2063 LTE--RKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERAR 2120
Query: 715 TIINHSRNGSYGESSLEAHIWQEEE------EVVQANRRCQ-----DMEYTIKNLHAKII 763
++ Y + L+ + +++ E+ A R + ++ ++KNL+ +
Sbjct: 2121 RLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLP 2180
Query: 764 EKDAMIKVLQQRSRKDAGKTDS 785
E A ++ + +R+ G+ +S
Sbjct: 2181 ELPADLEAILERNENLEGELES 2202
Score = 47.4 bits (111), Expect = 7e-05
Identities = 97/424 (22%), Positives = 164/424 (38%), Gaps = 63/424 (14%)
Query: 310 PPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPE 369
PP K S +K GL Y P + KP P Q + QPPP
Sbjct: 1147 PPPPSSKVSSHSSQATKDSGVGLKYSASTP-----VRKPRPGQQDGKEGS-----QPPPA 1196
Query: 370 YG------VTSRPCQLPFPST-------MQQHSPMSSQTSSASGP-----LHSV---SLP 408
G + S +L FPS Q+ S + Q P +++V P
Sbjct: 1197 SGYWVYSPIRSGLHKL-FPSRDADSGGDSQEESELDDQEEPPFVPPPGYMMYTVLPDGSP 1255
Query: 409 LPLPMALGAPQPPPAASPSQQLGPD--AFAIVERAQQMVEILTEENRVLHQELQG-YYDN 465
+P MAL AP PPP + S+ L P + MV N + G + N
Sbjct: 1256 VPQGMALYAP-PPPLPNNSRPLTPGTVVYGPPPAGAPMVYGPPPPNFSIPFIPMGVLHCN 1314
Query: 466 ADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLH-------DFNRDL 518
+ H E E+ R+ + + L KS + E +A + + E E+ LH + L
Sbjct: 1315 VPEHHNLENEVSRLEDIMQHL-KSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSL 1373
Query: 519 RDRLETANRQLSSREYEGHEDKAAEGHYASQNKEF-----LKEKEKLEMELAAVRTASED 573
+E +R + R+ + +G+ S E LK E + E+ +
Sbjct: 1374 ECEVEELHRTVQKRQ---QQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLK 1430
Query: 574 HRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRL 633
R + D+ L+ A++ + +E+ + VEK +++L Q +S E+ E+ +
Sbjct: 1431 RRSELREADRLLAEAESELSCTKEKTKNA---VEKFTDAKRSLLQTESDAEELERRAQET 1487
Query: 634 RTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEAD---MTKWEQK 690
L + LR+ Q A E + E+++E + + A ++D ++K ++K
Sbjct: 1488 AVNLVKADQQLRSLQ-----ADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEK 1542
Query: 691 YLEE 694
EE
Sbjct: 1543 LTEE 1546
Score = 40.4 bits (93), Expect = 0.008
Identities = 62/351 (17%), Positives = 136/351 (38%), Gaps = 27/351 (7%)
Query: 438 VERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLD 497
+E+ ++ ++++ + EL+ D L ELQ + ++ V K +
Sbjct: 1677 IEKEEENLQVVLRQMSKHKTELKNILD---MLQLENHELQGLKLQHDQRVSELEKTQVA- 1732
Query: 498 KAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFL-KE 556
+ KLE + L ++ + +E +QL R+ E AE E L KE
Sbjct: 1733 -VLEEKLE--LENLQQISQQQKGEIEW-QKQLLERDKREIERMTAESRALQSCVECLSKE 1788
Query: 557 KEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQAL 616
KE L+ + +R + ++ Q+ + KLE +R+ Q ++++ + + +L
Sbjct: 1789 KEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSL 1848
Query: 617 TQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEER 676
SA +++ Q +R L+ EL ++ + ++ L E R
Sbjct: 1849 HNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTR----- 1903
Query: 677 ILALEADMTKWEQKY---LEESTIRHFAMNAAATAAAERDTTIINH-------SRNGSYG 726
L+ D+++W ++ +E + + E ++ +
Sbjct: 1904 ---LQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESE 1960
Query: 727 ESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSR 777
ES LE +E+ Q + D + + + +K++ + ++ LQ+ R
Sbjct: 1961 ESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEER 2011
Score = 39.7 bits (91), Expect = 0.014
Identities = 87/438 (19%), Positives = 172/438 (39%), Gaps = 66/438 (15%)
Query: 437 IVERAQQMVEILTEENRVLHQELQGYYDNADKL--------HKFEKELQRISEAYESLVK 488
I + +Q+ E N L ++L+G + + + E +++ + E+L++
Sbjct: 592 IKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQ 651
Query: 489 STTK----RESLD------KAMRNKL---EGEIRRLHDFNRDLRDRLETANRQLSSREYE 535
T+ R+ L+ + MR +L E ++ H+ N L+ LS+ E E
Sbjct: 652 RLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQ----TQGDLSAYEAE 707
Query: 536 GHEDKAAEGHYASQNKEFLKEKEKL-EMELAAVRTASEDHRRHIEILDQALSNAQARVIK 594
A+Q KE L++ +L ++E +A++ E R QAL NA +
Sbjct: 708 LEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKER-------QALKNALGKAQF 760
Query: 595 LEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLER------ELDALRTQQ 648
EE+ +E K++ LQ L+ + + + L R +D LR +
Sbjct: 761 SEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKL 820
Query: 649 KHGNGQ-PANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAAT 707
K G G+ + P L ++++ ILA +KWE+ +E+ +R +
Sbjct: 821 KLGTGEMNIHSPSDVLGKSLADLQKQFSEILA----RSKWER---DEAQVRERKLQEEMA 873
Query: 708 AAAERDTTIINHSRNG---------SYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNL 758
E+ T R ++ + EA I Q E E+ + ME
Sbjct: 874 LQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLT 933
Query: 759 HAKIIEKD-------AMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLT 811
++ E D A ++ L+++ + + K+ + + + A T + L
Sbjct: 934 DLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDK---LA 990
Query: 812 SSQLAEEKKEEKTWKGSI 829
+++L K + K+ G++
Sbjct: 991 TAELTIAKDQLKSLHGTV 1008
Score = 35.8 bits (81), Expect = 0.20
Identities = 71/357 (19%), Positives = 147/357 (41%), Gaps = 29/357 (8%)
Query: 428 QQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLV 487
+ L DA + + + EIL E N+++ + + + K K +ELQ++ + E
Sbjct: 1499 RSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 1558
Query: 488 KSTTKRESLDKAMRNKLE---GEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEG 544
++ + K L+ E+ +L + + +RQL ++ E H +G
Sbjct: 1559 RNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELH---LLQG 1615
Query: 545 HYASQNKEFLKEKEKL-EMELAAVRTASEDHRRHIEILDQALSNAQARV-IKLEEELREK 602
Q K L+E +L E E+ T +H R ++ L + LS + + +++ E +
Sbjct: 1616 SMV-QAKADLQEALRLGETEV----TEKCNHIREVKSLLEELSFQKGELNVQISERKTQL 1670
Query: 603 QAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLE---RELDALRTQQKHGNGQPANMP 659
+++EK ++ L + K + + + L+ EL L+ Q + Q +
Sbjct: 1671 TLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQ----HDQRVSEL 1726
Query: 660 EYNAPALLE--LVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTII 717
E A+LE L E ++I + +W+++ LE R A + A + +
Sbjct: 1727 EKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDK-REIERMTAESRALQSCVECL 1785
Query: 718 NHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQ 774
+ + + + IW E+++ Q R E K + + + + ++ LQQ
Sbjct: 1786 SKEKE----DLQEKCDIW--EKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQ 1836
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 57.0 bits (136), Expect = 8e-08
Identities = 98/396 (24%), Positives = 160/396 (40%), Gaps = 69/396 (17%)
Query: 451 ENRV--LHQELQGYYDNADKLHKFEKELQRI-SEAYESLVKSTTKRESLDKAMRNKLEGE 507
EN+V L +E+ G + KL K +K LQ +A + L K +L KA + KLE +
Sbjct: 972 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQ 1030
Query: 508 IRRLH---DFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQN-KEFLKEK-EKLEM 562
+ L + + +R LE A R+L EG E +N K+ L E+ +K +
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKL-----EGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 563 ELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSA 622
EL A+ ED + L + L QAR+ +LEEEL ++ KVEK
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEK----------- 1134
Query: 623 CEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEA 682
LR+ L REL+ + + + G + +E+ +++E +
Sbjct: 1135 ----------LRSDLSRELEEISERLEEAGGATS--------VQIEMNKKREAEFQKMRR 1176
Query: 683 DMTKWEQKYLEESTIRHFAMNAA-----ATAAAERDTTIINHSR-----NGSYGESSLEA 732
D LEE+T++H A AA A + AE I N R E LE
Sbjct: 1177 D--------LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Query: 733 -HIWQEEEEVVQA----NRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRK---DAGKTD 784
+ E++++A + C+ +E + +K E + L + K + G+
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288
Query: 785 SSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKK 820
+ + T+++Q QL EE K
Sbjct: 1289 RQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVK 1324
Score = 50.1 bits (118), Expect = 1e-05
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 53/346 (15%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNA----DKLHKFEKEL-QRISEAYESLVKSTTKR 493
E ++ +L++ N + Q Y +A ++L + +K+L QR+ EA E++ K
Sbjct: 1352 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKC 1411
Query: 494 ESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGH-------EDKAAEGHY 546
SL+K +++L+ EI DL +E +N ++ + + E K
Sbjct: 1412 SSLEKT-KHRLQNEIE-------DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEES 1463
Query: 547 ASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYV 606
S+ + KE L EL ++ A E+ H+E + N Q + L E+L +
Sbjct: 1464 QSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTI 1523
Query: 607 EKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPAL 666
++EK+++ L + E+ME L+ L+ +H G+ A
Sbjct: 1524 HELEKVRKQL--------EAEKME------LQSALEEAEASLEHEEGKILR-------AQ 1562
Query: 667 LELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYG 726
LE + K E +E + + +++ +E++ H + + + + +T SRN +
Sbjct: 1563 LEFNQIKAE----IERKLAEKDEE-MEQAKRNHLRVVDSLQTSLDAET----RSRNEALR 1613
Query: 727 -ESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKV 771
+ +E + + E ++ ANR + + +K+L + + KD I++
Sbjct: 1614 VKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLL--KDTQIQL 1657
Score = 46.6 bits (109), Expect = 1e-04
Identities = 94/441 (21%), Positives = 176/441 (39%), Gaps = 101/441 (22%)
Query: 439 ERAQQMVEILTEENRVLHQEL----QGYYDNADKLHKFEKE----LQRISEAYESLVKST 490
E +Q +E +E R L EL Y ++ + L F++E + IS+ E L S
Sbjct: 1461 EESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSG 1520
Query: 491 TKRESLDKAMRNKLEGEIRRL------------HDFNRDLRDRLE------TANRQLSSR 532
L+K +R +LE E L H+ + LR +LE R+L+ +
Sbjct: 1521 KTIHELEK-VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Query: 533 EYEGHEDK------------AAEGHYASQNKEFLKEKEKLE-------MELAAVRTASED 573
+ E + K + + S+N E L+ K+K+E ++L+ + +
Sbjct: 1580 DEEMEQAKRNHLRVVDSLQTSLDAETRSRN-EALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 574 HRRHIEILDQALSNAQARV---IKLEEELREKQAYVEKVEKLQQA-LTQLQSACEKREQM 629
++ ++ L L + Q ++ ++ ++L+E A VE+ L QA L +L++ E+ E
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE-- 1696
Query: 630 ERRLRTWLEREL--DALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKW 687
R R E+EL + R Q H L+ +K++ L T+
Sbjct: 1697 --RSRKLAEQELIETSERVQLLHSQNT-------------SLINQKKKMDADLSQLQTEV 1741
Query: 688 EQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRR 747
E+ E A A AA + + +E++ R
Sbjct: 1742 EEAVQECRNAEEKAKKAITDAAM-------------------MAEELKKEQDTSAHLERM 1782
Query: 748 CQDMEYTIKNLHAKIIEKDAM--------IKVLQQRSRKDAGKTDSSSLRPARSVPSIAA 799
++ME TIK+L ++ E + + ++ L+ R R+ + ++ R A SV +
Sbjct: 1783 KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 800 ATGTHSRQTSLTSSQLAEEKK 820
+ R+ + Q E++K
Sbjct: 1843 S----ERRIKELTYQTEEDRK 1859
Score = 43.9 bits (102), Expect = 7e-04
Identities = 64/316 (20%), Positives = 135/316 (42%), Gaps = 18/316 (5%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E ++MV +L E+N L ++Q DN + +L + E+ VK +R ++
Sbjct: 872 ELEEKMVSLLQEKND-LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEE 930
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKE 558
M +L + R+L D +L+ ++ L+ E E H A E + +E E
Sbjct: 931 EMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKH---ATENKVKNLTEEMAGLDE 987
Query: 559 ---KLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA 615
KL E A++ A + ++ + ++ +KLE+++ + + +E+ +K++
Sbjct: 988 IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMD 1047
Query: 616 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHG----NGQPANMPEYNAPALLELVR 671
L + + E ++ + LE + L + K N A + + A L
Sbjct: 1048 LERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA-----LGS 1102
Query: 672 EKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLE 731
+ ++++ L+A + + E++ E T R A + R+ I+ + G +S++
Sbjct: 1103 QLQKKLKELQARIEELEEELEAERTAR--AKVEKLRSDLSRELEEISERLEEAGGATSVQ 1160
Query: 732 AHIWQEEEEVVQANRR 747
+ ++ E Q RR
Sbjct: 1161 IEMNKKREAEFQKMRR 1176
Score = 37.7 bits (86), Expect = 0.052
Identities = 43/219 (19%), Positives = 95/219 (43%), Gaps = 24/219 (10%)
Query: 437 IVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESL 496
++E ++++ + ++ +++Q+ + D + + E+ +Q A E K+ T +
Sbjct: 1706 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMM 1765
Query: 497 DKAMRNK------LEGEIRRLHDFNRDLRDRLETANR-----------QLSSREYEGHED 539
+ ++ + LE + + +DL+ RL+ A + +L +R E +
Sbjct: 1766 AEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENE 1825
Query: 540 KAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARV--IKLEE 597
AE +N E +K K E + + +E+ R+++ L + Q +V K +
Sbjct: 1826 LEAE---QKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQA 1882
Query: 598 ELREKQAY--VEKVEKLQQALTQLQSACEKREQMERRLR 634
E E+QA + K K+Q L + + + E +LR
Sbjct: 1883 EEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLR 1921
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 57.0 bits (136), Expect = 8e-08
Identities = 88/402 (21%), Positives = 161/402 (40%), Gaps = 55/402 (13%)
Query: 434 AFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKR 493
A A ER + ++ +E V +E D + ++ELQ++ ++ E+ +++ ++
Sbjct: 1382 AKAQAEREAKELQQRMQEEVVRREEAA--VDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1439
Query: 494 ESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEF 553
+ R ++E EIR + R +LE RQ E E +A +Q ++
Sbjct: 1440 AEAAERSRLRIEEEIRVV-------RLQLEATERQRGGAEGELQALRARAEEAEAQKRQA 1492
Query: 554 LKEKEKL--------------EMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL 599
+E E+L E+ELA+ A + R + QAL + + + E L
Sbjct: 1493 QEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRL 1552
Query: 600 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMP 659
R QA VE+ ++Q AL Q + E Q +R +L+ ++ Q
Sbjct: 1553 R--QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610
Query: 660 EYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINH 719
E A E R +EE E ++ +W+ K E +R A A
Sbjct: 1611 ERRAQQQAEAERAREE----AERELERWQLKANEALRLRLQAEEVA-------------- 1652
Query: 720 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD 779
+ S ++ E Q+EE +A RR + E ++ ++ E++ ++ R+
Sbjct: 1653 -QQKSLAQAEAEK---QKEEAEREARRRGKAEEQAVR--QRELAEQEL------EKQRQL 1700
Query: 780 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKE 821
A T L + + + A T +Q L +LA ++E
Sbjct: 1701 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQRE 1742
Score = 52.8 bits (125), Expect = 2e-06
Identities = 86/366 (23%), Positives = 157/366 (42%), Gaps = 37/366 (10%)
Query: 443 QMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRN 502
++ I + L + Q + A + +E +R EA E + KS E + +
Sbjct: 1947 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2006
Query: 503 KLEGEIRRLH---DFNRDLRDRLETAN-RQLSSREYEGHEDKAAEGH---YASQNKEFLK 555
LE E+ RL + R LR+R E + RQL + + AE +A Q KE
Sbjct: 2007 ALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE--- 2062
Query: 556 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQ-- 613
++L+ L ++ + R E +A A+ ++ E E + + VE+ E+L+
Sbjct: 2063 --QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 614 -----QALTQLQSACEK-REQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALL 667
QA Q Q+A EK R++ E+ + E ALR Q++ + + ++ L
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR-QKQAADAEMEKHKKFAEQTLR 2179
Query: 668 ELVR-EKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI---INHSRNG 723
+ + E+E L L+ + T ++ L+E R + A AT AA + + + + R
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQR---LKAEATEAARQRSQVEEELFSVRVQ 2236
Query: 724 SYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKT 783
S L+A I E ++ +D + T + L E + M +V ++ +R
Sbjct: 2237 MEELSKLKARIEAENRALI-----LRDKDNTQRFLQE---EAEKMKQVAEEAARLSVAAQ 2288
Query: 784 DSSSLR 789
+++ LR
Sbjct: 2289 EAARLR 2294
Score = 47.8 bits (112), Expect = 5e-05
Identities = 98/418 (23%), Positives = 168/418 (40%), Gaps = 64/418 (15%)
Query: 436 AIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
A+ E A++ ++ E+ Q + A+KL + + +EA +L + + E
Sbjct: 1808 ALAEEAKRQRQLAEED--AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENER 1865
Query: 496 L-----DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGH----EDKAAEGHY 546
L D+A + + E H D+ +RL R+ S E E ED +
Sbjct: 1866 LRRLAEDEAFQRRRLEEQAAQH--KADIEERLAQL-RKASDSELERQKGLVEDTLRQRRQ 1922
Query: 547 ASQNKEFLKE--------KEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEE 598
+ LK K +LE+EL +R+ +ED R E L A+ R + EEE
Sbjct: 1923 VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE--QAELEAARQRQLAAEEE 1980
Query: 599 LREKQAYVEKVEKL----QQALTQLQSACEKREQME------RRLRTWLERELDALRTQQ 648
R ++A E+V+K ++A Q ++A E+ E+++ RRLR E+E A + Q
Sbjct: 1981 RRRREA-EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQE-SARQLQL 2038
Query: 649 KHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATA 708
Q E A A V++KE+ + + EQ L++ +R A AA A
Sbjct: 2039 AQEAAQKRLQAEEKAHAF--AVQQKEQEL----QQTLQQEQSVLDQ--LRGEA-EAARRA 2089
Query: 709 AAERDTTIINHSRNGSYGESSLE--AHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKD 766
A E + + R + +E + Q EE QA + Q
Sbjct: 2090 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ----------------- 2132
Query: 767 AMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKT 824
A + L++ + ++A + + R + A H + T Q A+ ++E T
Sbjct: 2133 AAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT 2190
Score = 38.9 bits (89), Expect = 0.023
Identities = 45/205 (21%), Positives = 84/205 (40%), Gaps = 29/205 (14%)
Query: 471 KFEKELQRISEAYESLVKSTTKRESLDKAM---RNKLEGEIRRLHDFNRDLRDRLETANR 527
+F K+ + I E +T ++ +L + + R + + + RL + +L E +
Sbjct: 2405 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2464
Query: 528 -----QLSSREYEG-------HEDKAAEGHYASQNKEFLK-------EKEKLEM----EL 564
QL S E + E +A + + S+ L+ EK KLE E+
Sbjct: 2465 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEV 2524
Query: 565 AAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACE 624
A + E+ +R + ++Q Q V +EE R + E V + Q+ L QL+
Sbjct: 2525 AKAQQLREEQQRQQQQMEQ---ERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2581
Query: 625 KREQMERRLRTWLERELDALRTQQK 649
++E++ L +L L Q +
Sbjct: 2582 QQEELLAEENQRLREQLQLLEEQHR 2606
Score = 38.1 bits (87), Expect = 0.040
Identities = 61/309 (19%), Positives = 121/309 (39%), Gaps = 62/309 (20%)
Query: 473 EKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSR 532
+++ +R+ E E + + + + + LE E +R + + + +RL+ ++S
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEET---QGFQRTLEAERQRQLEMSAEA-ERLKLRVAEMSRA 2395
Query: 533 EYEGHED-------------KAAEGHYASQNK--------------------------EF 553
+ ED K A+Q K E
Sbjct: 2396 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAEL 2455
Query: 554 LKEKEKLEMELAAVRTASEDHR--------RHIEILDQALSNAQARVIKLE-----EELR 600
+EKEKL+ E ++ SE+ + + + L Q+ + + +++ E E+ +
Sbjct: 2456 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2515
Query: 601 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE 660
+Q + ++V K QQ + Q ++ EQ +RL +E +A R Q + G E
Sbjct: 2516 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME---EARRRQHEAEEGVRRKQEE 2572
Query: 661 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS 720
LE R ++E +LA E + + + LEE A + TA+ T + +
Sbjct: 2573 LQQ---LEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNG 2629
Query: 721 RNGSYGESS 729
R+ G ++
Sbjct: 2630 RDALDGPAA 2638
Score = 36.2 bits (82), Expect = 0.15
Identities = 53/266 (19%), Positives = 107/266 (40%), Gaps = 27/266 (10%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E A++ + + E+ + E++G +L E +++ E + T R L+
Sbjct: 1014 EPARECAQRIAEQQKA-QAEVEGLGKGVARL---SAEAEKVLALPEPSPAAPTLRSELEL 1069
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETAN-----RQLSSREYEGHEDKAAEGHYASQNKEF 553
+ G++ ++ + ++L+T + Q + HE++ E
Sbjct: 1070 TL-----GKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPAT--- 1121
Query: 554 LKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEK----- 608
L E E + L +R +E + + L L AQ +L++ E+ VE+
Sbjct: 1122 LPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERV 1181
Query: 609 ---VEKLQQALTQLQSACEKREQMERRLRTWLER--ELDALRTQQKHGNGQPANMPEYNA 663
+E+ Q L Q + EQ+ R+LR + E L A + Q MP ++
Sbjct: 1182 AQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1241
Query: 664 PALLELVREKEERILALEADMTKWEQ 689
A+ E +R+++ + +E K E+
Sbjct: 1242 QAVREQLRQEQALLEEIERHGEKVEE 1267
Score = 34.7 bits (78), Expect = 0.44
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 22/163 (13%)
Query: 473 EKELQRI-SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSS 531
++ELQR+ +EA E+ + + E L ++R ++E E+ +L + R+E NR L
Sbjct: 2206 DEELQRLKAEATEAARQRSQVEEELF-SVRVQME-ELSKL-------KARIEAENRALIL 2256
Query: 532 REYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQAR 591
R DK + + E +K+ + E A + A+++ R ++ ++ L+ +A
Sbjct: 2257 R------DKDNTQRFLQEEAEKMKQVAE---EAARLSVAAQEAARLRQLAEEDLAQQRAL 2307
Query: 592 VIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLR 634
K+ L+EK V++ +L+ LQ E ++ RRL+
Sbjct: 2308 AEKM---LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2347
Score = 34.3 bits (77), Expect = 0.57
Identities = 49/196 (25%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 445 VEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKA-MRNK 503
VE +R LHQ ++ + ++ E +L S A + R L A + N
Sbjct: 551 VEAQLGSHRGLHQSIEEFRAKIERARSDEGQL---SPATRGAYRDCLGRLDLQYAKLLNS 607
Query: 504 LEGEIRRL---HDFNRDLRDRLETANRQLSSREYEGHEDK-----AAEGHYASQNKEF-L 554
+ +R L H F L N + D+ A + Y++ +E L
Sbjct: 608 SKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELEL 667
Query: 555 KEKEKLEMELAAVRTASEDH--RRHIEILDQALSNAQARVIKL----EEELREKQAYVEK 608
KEK+ E++ A R EDH R +E AL + +++L E L+E AY +
Sbjct: 668 KEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQF 727
Query: 609 VEKLQQALTQLQSACE 624
+++A QLQ E
Sbjct: 728 FSDVREAEGQLQKLQE 743
Score = 31.2 bits (69), Expect = 4.8
Identities = 41/194 (21%), Positives = 84/194 (43%), Gaps = 29/194 (14%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKE-----LQRISEAYESLVKSTTKR 493
ER ++ + L E L QE + ++++ ++E Q + +++ S S +R
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 494 ESLDKAMRNKLE-------GEIRRLHDFNRDLRDRLETANRQL--SSREYEGHEDKAAEG 544
E + + KLE + ++L + + + ++E ++L S E + +A EG
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2565
Query: 545 HYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQA 604
Q +E ++LE + R+ E+L + + ++ LEE+ R A
Sbjct: 2566 VRRKQ-----EELQQLEQQ----------RRQQEELLAEENQRLREQLQLLEEQHRAALA 2610
Query: 605 YVEKVEKLQQALTQ 618
+ E+V Q A T+
Sbjct: 2611 HSEEVTASQVAATK 2624
Score = 31.2 bits (69), Expect = 4.8
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 16/110 (14%)
Query: 154 QSARQEPQGQEHQV--------DNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQ 205
Q+ +QE QE Q +++++++ Q + E+L E AKAQ R +Q
Sbjct: 2477 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ--LREEQ 2534
Query: 206 QQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQ 255
Q+QQQQ +A S E R + A G K E L++L+Q
Sbjct: 2535 QRQQQQMEQERQRLVA------SMEEARRRQHEAEEGVRRKQEELQQLEQ 2578
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 57.0 bits (136), Expect = 8e-08
Identities = 88/402 (21%), Positives = 161/402 (40%), Gaps = 55/402 (13%)
Query: 434 AFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKR 493
A A ER + ++ +E V +E D + ++ELQ++ ++ E+ +++ ++
Sbjct: 1386 AKAQAEREAKELQQRMQEEVVRREEAA--VDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1443
Query: 494 ESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEF 553
+ R ++E EIR + R +LE RQ E E +A +Q ++
Sbjct: 1444 AEAAERSRLRIEEEIRVV-------RLQLEATERQRGGAEGELQALRARAEEAEAQKRQA 1496
Query: 554 LKEKEKL--------------EMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL 599
+E E+L E+ELA+ A + R + QAL + + + E L
Sbjct: 1497 QEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRL 1556
Query: 600 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMP 659
R QA VE+ ++Q AL Q + E Q +R +L+ ++ Q
Sbjct: 1557 R--QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1614
Query: 660 EYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINH 719
E A E R +EE E ++ +W+ K E +R A A
Sbjct: 1615 ERRAQQQAEAERAREE----AERELERWQLKANEALRLRLQAEEVA-------------- 1656
Query: 720 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD 779
+ S ++ E Q+EE +A RR + E ++ ++ E++ ++ R+
Sbjct: 1657 -QQKSLAQAEAEK---QKEEAEREARRRGKAEEQAVR--QRELAEQEL------EKQRQL 1704
Query: 780 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKE 821
A T L + + + A T +Q L +LA ++E
Sbjct: 1705 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQRE 1746
Score = 52.8 bits (125), Expect = 2e-06
Identities = 86/366 (23%), Positives = 157/366 (42%), Gaps = 37/366 (10%)
Query: 443 QMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRN 502
++ I + L + Q + A + +E +R EA E + KS E + +
Sbjct: 1951 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2010
Query: 503 KLEGEIRRLH---DFNRDLRDRLETAN-RQLSSREYEGHEDKAAEGH---YASQNKEFLK 555
LE E+ RL + R LR+R E + RQL + + AE +A Q KE
Sbjct: 2011 ALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE--- 2066
Query: 556 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQ-- 613
++L+ L ++ + R E +A A+ ++ E E + + VE+ E+L+
Sbjct: 2067 --QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2124
Query: 614 -----QALTQLQSACEK-REQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALL 667
QA Q Q+A EK R++ E+ + E ALR Q++ + + ++ L
Sbjct: 2125 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR-QKQAADAEMEKHKKFAEQTLR 2183
Query: 668 ELVR-EKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI---INHSRNG 723
+ + E+E L L+ + T ++ L+E R + A AT AA + + + + R
Sbjct: 2184 QKAQVEQELTTLRLQLEETDHQKNLLDEELQR---LKAEATEAARQRSQVEEELFSVRVQ 2240
Query: 724 SYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKT 783
S L+A I E ++ +D + T + L E + M +V ++ +R
Sbjct: 2241 MEELSKLKARIEAENRALI-----LRDKDNTQRFLQE---EAEKMKQVAEEAARLSVAAQ 2292
Query: 784 DSSSLR 789
+++ LR
Sbjct: 2293 EAARLR 2298
Score = 47.8 bits (112), Expect = 5e-05
Identities = 98/418 (23%), Positives = 168/418 (40%), Gaps = 64/418 (15%)
Query: 436 AIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
A+ E A++ ++ E+ Q + A+KL + + +EA +L + + E
Sbjct: 1812 ALAEEAKRQRQLAEED--AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENER 1869
Query: 496 L-----DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGH----EDKAAEGHY 546
L D+A + + E H D+ +RL R+ S E E ED +
Sbjct: 1870 LRRLAEDEAFQRRRLEEQAAQH--KADIEERLAQL-RKASDSELERQKGLVEDTLRQRRQ 1926
Query: 547 ASQNKEFLKE--------KEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEE 598
+ LK K +LE+EL +R+ +ED R E L A+ R + EEE
Sbjct: 1927 VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE--QAELEAARQRQLAAEEE 1984
Query: 599 LREKQAYVEKVEKL----QQALTQLQSACEKREQME------RRLRTWLERELDALRTQQ 648
R ++A E+V+K ++A Q ++A E+ E+++ RRLR E+E A + Q
Sbjct: 1985 RRRREA-EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQE-SARQLQL 2042
Query: 649 KHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATA 708
Q E A A V++KE+ + + EQ L++ +R A AA A
Sbjct: 2043 AQEAAQKRLQAEEKAHAF--AVQQKEQEL----QQTLQQEQSVLDQ--LRGEA-EAARRA 2093
Query: 709 AAERDTTIINHSRNGSYGESSLE--AHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKD 766
A E + + R + +E + Q EE QA + Q
Sbjct: 2094 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ----------------- 2136
Query: 767 AMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKT 824
A + L++ + ++A + + R + A H + T Q A+ ++E T
Sbjct: 2137 AAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT 2194
Score = 38.9 bits (89), Expect = 0.023
Identities = 45/205 (21%), Positives = 84/205 (40%), Gaps = 29/205 (14%)
Query: 471 KFEKELQRISEAYESLVKSTTKRESLDKAM---RNKLEGEIRRLHDFNRDLRDRLETANR 527
+F K+ + I E +T ++ +L + + R + + + RL + +L E +
Sbjct: 2409 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2468
Query: 528 -----QLSSREYEG-------HEDKAAEGHYASQNKEFLK-------EKEKLEM----EL 564
QL S E + E +A + + S+ L+ EK KLE E+
Sbjct: 2469 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEV 2528
Query: 565 AAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACE 624
A + E+ +R + ++Q Q V +EE R + E V + Q+ L QL+
Sbjct: 2529 AKAQQLREEQQRQQQQMEQ---ERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2585
Query: 625 KREQMERRLRTWLERELDALRTQQK 649
++E++ L +L L Q +
Sbjct: 2586 QQEELLAEENQRLREQLQLLEEQHR 2610
Score = 38.1 bits (87), Expect = 0.040
Identities = 61/309 (19%), Positives = 121/309 (39%), Gaps = 62/309 (20%)
Query: 473 EKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSR 532
+++ +R+ E E + + + + + LE E +R + + + +RL+ ++S
Sbjct: 2344 QEQARRLQEDKEQMAQQLAEET---QGFQRTLEAERQRQLEMSAEA-ERLKLRVAEMSRA 2399
Query: 533 EYEGHED-------------KAAEGHYASQNK--------------------------EF 553
+ ED K A+Q K E
Sbjct: 2400 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAEL 2459
Query: 554 LKEKEKLEMELAAVRTASEDHR--------RHIEILDQALSNAQARVIKLE-----EELR 600
+EKEKL+ E ++ SE+ + + + L Q+ + + +++ E E+ +
Sbjct: 2460 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2519
Query: 601 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE 660
+Q + ++V K QQ + Q ++ EQ +RL +E +A R Q + G E
Sbjct: 2520 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME---EARRRQHEAEEGVRRKQEE 2576
Query: 661 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS 720
LE R ++E +LA E + + + LEE A + TA+ T + +
Sbjct: 2577 LQQ---LEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNG 2633
Query: 721 RNGSYGESS 729
R+ G ++
Sbjct: 2634 RDALDGPAA 2642
Score = 36.2 bits (82), Expect = 0.15
Identities = 53/266 (19%), Positives = 107/266 (40%), Gaps = 27/266 (10%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E A++ + + E+ + E++G +L E +++ E + T R L+
Sbjct: 1018 EPARECAQRIAEQQKA-QAEVEGLGKGVARL---SAEAEKVLALPEPSPAAPTLRSELEL 1073
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETAN-----RQLSSREYEGHEDKAAEGHYASQNKEF 553
+ G++ ++ + ++L+T + Q + HE++ E
Sbjct: 1074 TL-----GKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPAT--- 1125
Query: 554 LKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEK----- 608
L E E + L +R +E + + L L AQ +L++ E+ VE+
Sbjct: 1126 LPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERV 1185
Query: 609 ---VEKLQQALTQLQSACEKREQMERRLRTWLER--ELDALRTQQKHGNGQPANMPEYNA 663
+E+ Q L Q + EQ+ R+LR + E L A + Q MP ++
Sbjct: 1186 AQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1245
Query: 664 PALLELVREKEERILALEADMTKWEQ 689
A+ E +R+++ + +E K E+
Sbjct: 1246 QAVREQLRQEQALLEEIERHGEKVEE 1271
Score = 34.7 bits (78), Expect = 0.44
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 22/163 (13%)
Query: 473 EKELQRI-SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSS 531
++ELQR+ +EA E+ + + E L ++R ++E E+ +L + R+E NR L
Sbjct: 2210 DEELQRLKAEATEAARQRSQVEEELF-SVRVQME-ELSKL-------KARIEAENRALIL 2260
Query: 532 REYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQAR 591
R DK + + E +K+ + E A + A+++ R ++ ++ L+ +A
Sbjct: 2261 R------DKDNTQRFLQEEAEKMKQVAE---EAARLSVAAQEAARLRQLAEEDLAQQRAL 2311
Query: 592 VIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLR 634
K+ L+EK V++ +L+ LQ E ++ RRL+
Sbjct: 2312 AEKM---LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2351
Score = 34.3 bits (77), Expect = 0.57
Identities = 49/196 (25%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 445 VEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKA-MRNK 503
VE +R LHQ ++ + ++ E +L S A + R L A + N
Sbjct: 555 VEAQLGSHRGLHQSIEEFRAKIERARSDEGQL---SPATRGAYRDCLGRLDLQYAKLLNS 611
Query: 504 LEGEIRRL---HDFNRDLRDRLETANRQLSSREYEGHEDK-----AAEGHYASQNKEF-L 554
+ +R L H F L N + D+ A + Y++ +E L
Sbjct: 612 SKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELEL 671
Query: 555 KEKEKLEMELAAVRTASEDH--RRHIEILDQALSNAQARVIKL----EEELREKQAYVEK 608
KEK+ E++ A R EDH R +E AL + +++L E L+E AY +
Sbjct: 672 KEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQF 731
Query: 609 VEKLQQALTQLQSACE 624
+++A QLQ E
Sbjct: 732 FSDVREAEGQLQKLQE 747
Score = 31.2 bits (69), Expect = 4.8
Identities = 41/194 (21%), Positives = 84/194 (43%), Gaps = 29/194 (14%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKE-----LQRISEAYESLVKSTTKR 493
ER ++ + L E L QE + ++++ ++E Q + +++ S S +R
Sbjct: 2450 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2509
Query: 494 ESLDKAMRNKLE-------GEIRRLHDFNRDLRDRLETANRQL--SSREYEGHEDKAAEG 544
E + + KLE + ++L + + + ++E ++L S E + +A EG
Sbjct: 2510 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2569
Query: 545 HYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQA 604
Q +E ++LE + R+ E+L + + ++ LEE+ R A
Sbjct: 2570 VRRKQ-----EELQQLEQQ----------RRQQEELLAEENQRLREQLQLLEEQHRAALA 2614
Query: 605 YVEKVEKLQQALTQ 618
+ E+V Q A T+
Sbjct: 2615 HSEEVTASQVAATK 2628
Score = 31.2 bits (69), Expect = 4.8
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 16/110 (14%)
Query: 154 QSARQEPQGQEHQV--------DNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQ 205
Q+ +QE QE Q +++++++ Q + E+L E AKAQ R +Q
Sbjct: 2481 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ--LREEQ 2538
Query: 206 QQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQ 255
Q+QQQQ +A S E R + A G K E L++L+Q
Sbjct: 2539 QRQQQQMEQERQRLVA------SMEEARRRQHEAEEGVRRKQEELQQLEQ 2582
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 57.0 bits (136), Expect = 8e-08
Identities = 88/402 (21%), Positives = 161/402 (40%), Gaps = 55/402 (13%)
Query: 434 AFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKR 493
A A ER + ++ +E V +E D + ++ELQ++ ++ E+ +++ ++
Sbjct: 1382 AKAQAEREAKELQQRMQEEVVRREEAA--VDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1439
Query: 494 ESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEF 553
+ R ++E EIR + R +LE RQ E E +A +Q ++
Sbjct: 1440 AEAAERSRLRIEEEIRVV-------RLQLEATERQRGGAEGELQALRARAEEAEAQKRQA 1492
Query: 554 LKEKEKL--------------EMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL 599
+E E+L E+ELA+ A + R + QAL + + + E L
Sbjct: 1493 QEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRL 1552
Query: 600 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMP 659
R QA VE+ ++Q AL Q + E Q +R +L+ ++ Q
Sbjct: 1553 R--QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610
Query: 660 EYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINH 719
E A E R +EE E ++ +W+ K E +R A A
Sbjct: 1611 ERRAQQQAEAERAREE----AERELERWQLKANEALRLRLQAEEVA-------------- 1652
Query: 720 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD 779
+ S ++ E Q+EE +A RR + E ++ ++ E++ ++ R+
Sbjct: 1653 -QQKSLAQAEAEK---QKEEAEREARRRGKAEEQAVR--QRELAEQEL------EKQRQL 1700
Query: 780 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKE 821
A T L + + + A T +Q L +LA ++E
Sbjct: 1701 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQRE 1742
Score = 52.8 bits (125), Expect = 2e-06
Identities = 86/366 (23%), Positives = 157/366 (42%), Gaps = 37/366 (10%)
Query: 443 QMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRN 502
++ I + L + Q + A + +E +R EA E + KS E + +
Sbjct: 1947 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2006
Query: 503 KLEGEIRRLH---DFNRDLRDRLETAN-RQLSSREYEGHEDKAAEGH---YASQNKEFLK 555
LE E+ RL + R LR+R E + RQL + + AE +A Q KE
Sbjct: 2007 ALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE--- 2062
Query: 556 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQ-- 613
++L+ L ++ + R E +A A+ ++ E E + + VE+ E+L+
Sbjct: 2063 --QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 614 -----QALTQLQSACEK-REQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALL 667
QA Q Q+A EK R++ E+ + E ALR Q++ + + ++ L
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR-QKQAADAEMEKHKKFAEQTLR 2179
Query: 668 ELVR-EKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI---INHSRNG 723
+ + E+E L L+ + T ++ L+E R + A AT AA + + + + R
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQR---LKAEATEAARQRSQVEEELFSVRVQ 2236
Query: 724 SYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKT 783
S L+A I E ++ +D + T + L E + M +V ++ +R
Sbjct: 2237 MEELSKLKARIEAENRALI-----LRDKDNTQRFLQE---EAEKMKQVAEEAARLSVAAQ 2288
Query: 784 DSSSLR 789
+++ LR
Sbjct: 2289 EAARLR 2294
Score = 47.8 bits (112), Expect = 5e-05
Identities = 98/418 (23%), Positives = 168/418 (40%), Gaps = 64/418 (15%)
Query: 436 AIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
A+ E A++ ++ E+ Q + A+KL + + +EA +L + + E
Sbjct: 1808 ALAEEAKRQRQLAEED--AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENER 1865
Query: 496 L-----DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGH----EDKAAEGHY 546
L D+A + + E H D+ +RL R+ S E E ED +
Sbjct: 1866 LRRLAEDEAFQRRRLEEQAAQH--KADIEERLAQL-RKASDSELERQKGLVEDTLRQRRQ 1922
Query: 547 ASQNKEFLKE--------KEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEE 598
+ LK K +LE+EL +R+ +ED R E L A+ R + EEE
Sbjct: 1923 VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE--QAELEAARQRQLAAEEE 1980
Query: 599 LREKQAYVEKVEKL----QQALTQLQSACEKREQME------RRLRTWLERELDALRTQQ 648
R ++A E+V+K ++A Q ++A E+ E+++ RRLR E+E A + Q
Sbjct: 1981 RRRREA-EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQE-SARQLQL 2038
Query: 649 KHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATA 708
Q E A A V++KE+ + + EQ L++ +R A AA A
Sbjct: 2039 AQEAAQKRLQAEEKAHAF--AVQQKEQEL----QQTLQQEQSVLDQ--LRGEA-EAARRA 2089
Query: 709 AAERDTTIINHSRNGSYGESSLE--AHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKD 766
A E + + R + +E + Q EE QA + Q
Sbjct: 2090 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ----------------- 2132
Query: 767 AMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKT 824
A + L++ + ++A + + R + A H + T Q A+ ++E T
Sbjct: 2133 AAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT 2190
Score = 38.9 bits (89), Expect = 0.023
Identities = 45/205 (21%), Positives = 84/205 (40%), Gaps = 29/205 (14%)
Query: 471 KFEKELQRISEAYESLVKSTTKRESLDKAM---RNKLEGEIRRLHDFNRDLRDRLETANR 527
+F K+ + I E +T ++ +L + + R + + + RL + +L E +
Sbjct: 2405 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2464
Query: 528 -----QLSSREYEG-------HEDKAAEGHYASQNKEFLK-------EKEKLEM----EL 564
QL S E + E +A + + S+ L+ EK KLE E+
Sbjct: 2465 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEV 2524
Query: 565 AAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACE 624
A + E+ +R + ++Q Q V +EE R + E V + Q+ L QL+
Sbjct: 2525 AKAQQLREEQQRQQQQMEQ---ERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2581
Query: 625 KREQMERRLRTWLERELDALRTQQK 649
++E++ L +L L Q +
Sbjct: 2582 QQEELLAEENQRLREQLQLLEEQHR 2606
Score = 38.1 bits (87), Expect = 0.040
Identities = 61/309 (19%), Positives = 121/309 (39%), Gaps = 62/309 (20%)
Query: 473 EKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSR 532
+++ +R+ E E + + + + + LE E +R + + + +RL+ ++S
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEET---QGFQRTLEAERQRQLEMSAEA-ERLKLRVAEMSRA 2395
Query: 533 EYEGHED-------------KAAEGHYASQNK--------------------------EF 553
+ ED K A+Q K E
Sbjct: 2396 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAEL 2455
Query: 554 LKEKEKLEMELAAVRTASEDHR--------RHIEILDQALSNAQARVIKLE-----EELR 600
+EKEKL+ E ++ SE+ + + + L Q+ + + +++ E E+ +
Sbjct: 2456 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2515
Query: 601 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE 660
+Q + ++V K QQ + Q ++ EQ +RL +E +A R Q + G E
Sbjct: 2516 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME---EARRRQHEAEEGVRRKQEE 2572
Query: 661 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS 720
LE R ++E +LA E + + + LEE A + TA+ T + +
Sbjct: 2573 LQQ---LEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNG 2629
Query: 721 RNGSYGESS 729
R+ G ++
Sbjct: 2630 RDALDGPAA 2638
Score = 36.2 bits (82), Expect = 0.15
Identities = 53/266 (19%), Positives = 107/266 (40%), Gaps = 27/266 (10%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E A++ + + E+ + E++G +L E +++ E + T R L+
Sbjct: 1014 EPARECAQRIAEQQKA-QAEVEGLGKGVARL---SAEAEKVLALPEPSPAAPTLRSELEL 1069
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETAN-----RQLSSREYEGHEDKAAEGHYASQNKEF 553
+ G++ ++ + ++L+T + Q + HE++ E
Sbjct: 1070 TL-----GKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPAT--- 1121
Query: 554 LKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEK----- 608
L E E + L +R +E + + L L AQ +L++ E+ VE+
Sbjct: 1122 LPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERV 1181
Query: 609 ---VEKLQQALTQLQSACEKREQMERRLRTWLER--ELDALRTQQKHGNGQPANMPEYNA 663
+E+ Q L Q + EQ+ R+LR + E L A + Q MP ++
Sbjct: 1182 AQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1241
Query: 664 PALLELVREKEERILALEADMTKWEQ 689
A+ E +R+++ + +E K E+
Sbjct: 1242 QAVREQLRQEQALLEEIERHGEKVEE 1267
Score = 34.7 bits (78), Expect = 0.44
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 22/163 (13%)
Query: 473 EKELQRI-SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSS 531
++ELQR+ +EA E+ + + E L ++R ++E E+ +L + R+E NR L
Sbjct: 2206 DEELQRLKAEATEAARQRSQVEEELF-SVRVQME-ELSKL-------KARIEAENRALIL 2256
Query: 532 REYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQAR 591
R DK + + E +K+ + E A + A+++ R ++ ++ L+ +A
Sbjct: 2257 R------DKDNTQRFLQEEAEKMKQVAE---EAARLSVAAQEAARLRQLAEEDLAQQRAL 2307
Query: 592 VIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLR 634
K+ L+EK V++ +L+ LQ E ++ RRL+
Sbjct: 2308 AEKM---LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2347
Score = 34.3 bits (77), Expect = 0.57
Identities = 49/196 (25%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 445 VEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKA-MRNK 503
VE +R LHQ ++ + ++ E +L S A + R L A + N
Sbjct: 551 VEAQLGSHRGLHQSIEEFRAKIERARSDEGQL---SPATRGAYRDCLGRLDLQYAKLLNS 607
Query: 504 LEGEIRRL---HDFNRDLRDRLETANRQLSSREYEGHEDK-----AAEGHYASQNKEF-L 554
+ +R L H F L N + D+ A + Y++ +E L
Sbjct: 608 SKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELEL 667
Query: 555 KEKEKLEMELAAVRTASEDH--RRHIEILDQALSNAQARVIKL----EEELREKQAYVEK 608
KEK+ E++ A R EDH R +E AL + +++L E L+E AY +
Sbjct: 668 KEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQF 727
Query: 609 VEKLQQALTQLQSACE 624
+++A QLQ E
Sbjct: 728 FSDVREAEGQLQKLQE 743
Score = 31.2 bits (69), Expect = 4.8
Identities = 41/194 (21%), Positives = 84/194 (43%), Gaps = 29/194 (14%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKE-----LQRISEAYESLVKSTTKR 493
ER ++ + L E L QE + ++++ ++E Q + +++ S S +R
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 494 ESLDKAMRNKLE-------GEIRRLHDFNRDLRDRLETANRQL--SSREYEGHEDKAAEG 544
E + + KLE + ++L + + + ++E ++L S E + +A EG
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2565
Query: 545 HYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQA 604
Q +E ++LE + R+ E+L + + ++ LEE+ R A
Sbjct: 2566 VRRKQ-----EELQQLEQQ----------RRQQEELLAEENQRLREQLQLLEEQHRAALA 2610
Query: 605 YVEKVEKLQQALTQ 618
+ E+V Q A T+
Sbjct: 2611 HSEEVTASQVAATK 2624
Score = 31.2 bits (69), Expect = 4.8
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 16/110 (14%)
Query: 154 QSARQEPQGQEHQV--------DNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQ 205
Q+ +QE QE Q +++++++ Q + E+L E AKAQ R +Q
Sbjct: 2477 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ--LREEQ 2534
Query: 206 QQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQ 255
Q+QQQQ +A S E R + A G K E L++L+Q
Sbjct: 2535 QRQQQQMEQERQRLVA------SMEEARRRQHEAEEGVRRKQEELQQLEQ 2578
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 57.0 bits (136), Expect = 8e-08
Identities = 88/402 (21%), Positives = 161/402 (40%), Gaps = 55/402 (13%)
Query: 434 AFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKR 493
A A ER + ++ +E V +E D + ++ELQ++ ++ E+ +++ ++
Sbjct: 1350 AKAQAEREAKELQQRMQEEVVRREEAA--VDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1407
Query: 494 ESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEF 553
+ R ++E EIR + R +LE RQ E E +A +Q ++
Sbjct: 1408 AEAAERSRLRIEEEIRVV-------RLQLEATERQRGGAEGELQALRARAEEAEAQKRQA 1460
Query: 554 LKEKEKL--------------EMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL 599
+E E+L E+ELA+ A + R + QAL + + + E L
Sbjct: 1461 QEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRL 1520
Query: 600 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMP 659
R QA VE+ ++Q AL Q + E Q +R +L+ ++ Q
Sbjct: 1521 R--QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1578
Query: 660 EYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINH 719
E A E R +EE E ++ +W+ K E +R A A
Sbjct: 1579 ERRAQQQAEAERAREE----AERELERWQLKANEALRLRLQAEEVA-------------- 1620
Query: 720 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD 779
+ S ++ E Q+EE +A RR + E ++ ++ E++ ++ R+
Sbjct: 1621 -QQKSLAQAEAEK---QKEEAEREARRRGKAEEQAVR--QRELAEQEL------EKQRQL 1668
Query: 780 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKE 821
A T L + + + A T +Q L +LA ++E
Sbjct: 1669 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQRE 1710
Score = 52.8 bits (125), Expect = 2e-06
Identities = 86/366 (23%), Positives = 157/366 (42%), Gaps = 37/366 (10%)
Query: 443 QMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRN 502
++ I + L + Q + A + +E +R EA E + KS E + +
Sbjct: 1915 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 1974
Query: 503 KLEGEIRRLH---DFNRDLRDRLETAN-RQLSSREYEGHEDKAAEGH---YASQNKEFLK 555
LE E+ RL + R LR+R E + RQL + + AE +A Q KE
Sbjct: 1975 ALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE--- 2030
Query: 556 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQ-- 613
++L+ L ++ + R E +A A+ ++ E E + + VE+ E+L+
Sbjct: 2031 --QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2088
Query: 614 -----QALTQLQSACEK-REQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALL 667
QA Q Q+A EK R++ E+ + E ALR Q++ + + ++ L
Sbjct: 2089 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR-QKQAADAEMEKHKKFAEQTLR 2147
Query: 668 ELVR-EKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI---INHSRNG 723
+ + E+E L L+ + T ++ L+E R + A AT AA + + + + R
Sbjct: 2148 QKAQVEQELTTLRLQLEETDHQKNLLDEELQR---LKAEATEAARQRSQVEEELFSVRVQ 2204
Query: 724 SYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKT 783
S L+A I E ++ +D + T + L E + M +V ++ +R
Sbjct: 2205 MEELSKLKARIEAENRALI-----LRDKDNTQRFLQE---EAEKMKQVAEEAARLSVAAQ 2256
Query: 784 DSSSLR 789
+++ LR
Sbjct: 2257 EAARLR 2262
Score = 47.8 bits (112), Expect = 5e-05
Identities = 98/418 (23%), Positives = 168/418 (40%), Gaps = 64/418 (15%)
Query: 436 AIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRES 495
A+ E A++ ++ E+ Q + A+KL + + +EA +L + + E
Sbjct: 1776 ALAEEAKRQRQLAEED--AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENER 1833
Query: 496 L-----DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGH----EDKAAEGHY 546
L D+A + + E H D+ +RL R+ S E E ED +
Sbjct: 1834 LRRLAEDEAFQRRRLEEQAAQH--KADIEERLAQL-RKASDSELERQKGLVEDTLRQRRQ 1890
Query: 547 ASQNKEFLKE--------KEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEE 598
+ LK K +LE+EL +R+ +ED R E L A+ R + EEE
Sbjct: 1891 VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE--QAELEAARQRQLAAEEE 1948
Query: 599 LREKQAYVEKVEKL----QQALTQLQSACEKREQME------RRLRTWLERELDALRTQQ 648
R ++A E+V+K ++A Q ++A E+ E+++ RRLR E+E A + Q
Sbjct: 1949 RRRREA-EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQE-SARQLQL 2006
Query: 649 KHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATA 708
Q E A A V++KE+ + + EQ L++ +R A AA A
Sbjct: 2007 AQEAAQKRLQAEEKAHAF--AVQQKEQEL----QQTLQQEQSVLDQ--LRGEA-EAARRA 2057
Query: 709 AAERDTTIINHSRNGSYGESSLE--AHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKD 766
A E + + R + +E + Q EE QA + Q
Sbjct: 2058 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ----------------- 2100
Query: 767 AMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKT 824
A + L++ + ++A + + R + A H + T Q A+ ++E T
Sbjct: 2101 AAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT 2158
Score = 38.9 bits (89), Expect = 0.023
Identities = 45/205 (21%), Positives = 84/205 (40%), Gaps = 29/205 (14%)
Query: 471 KFEKELQRISEAYESLVKSTTKRESLDKAM---RNKLEGEIRRLHDFNRDLRDRLETANR 527
+F K+ + I E +T ++ +L + + R + + + RL + +L E +
Sbjct: 2373 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2432
Query: 528 -----QLSSREYEG-------HEDKAAEGHYASQNKEFLK-------EKEKLEM----EL 564
QL S E + E +A + + S+ L+ EK KLE E+
Sbjct: 2433 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEV 2492
Query: 565 AAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACE 624
A + E+ +R + ++Q Q V +EE R + E V + Q+ L QL+
Sbjct: 2493 AKAQQLREEQQRQQQQMEQ---ERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2549
Query: 625 KREQMERRLRTWLERELDALRTQQK 649
++E++ L +L L Q +
Sbjct: 2550 QQEELLAEENQRLREQLQLLEEQHR 2574
Score = 38.1 bits (87), Expect = 0.040
Identities = 61/309 (19%), Positives = 121/309 (39%), Gaps = 62/309 (20%)
Query: 473 EKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSR 532
+++ +R+ E E + + + + + LE E +R + + + +RL+ ++S
Sbjct: 2308 QEQARRLQEDKEQMAQQLAEET---QGFQRTLEAERQRQLEMSAEA-ERLKLRVAEMSRA 2363
Query: 533 EYEGHED-------------KAAEGHYASQNK--------------------------EF 553
+ ED K A+Q K E
Sbjct: 2364 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAEL 2423
Query: 554 LKEKEKLEMELAAVRTASEDHR--------RHIEILDQALSNAQARVIKLE-----EELR 600
+EKEKL+ E ++ SE+ + + + L Q+ + + +++ E E+ +
Sbjct: 2424 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2483
Query: 601 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE 660
+Q + ++V K QQ + Q ++ EQ +RL +E +A R Q + G E
Sbjct: 2484 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME---EARRRQHEAEEGVRRKQEE 2540
Query: 661 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS 720
LE R ++E +LA E + + + LEE A + TA+ T + +
Sbjct: 2541 LQQ---LEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNG 2597
Query: 721 RNGSYGESS 729
R+ G ++
Sbjct: 2598 RDALDGPAA 2606
Score = 36.2 bits (82), Expect = 0.15
Identities = 53/266 (19%), Positives = 107/266 (40%), Gaps = 27/266 (10%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDK 498
E A++ + + E+ + E++G +L E +++ E + T R L+
Sbjct: 982 EPARECAQRIAEQQKA-QAEVEGLGKGVARL---SAEAEKVLALPEPSPAAPTLRSELEL 1037
Query: 499 AMRNKLEGEIRRLHDFNRDLRDRLETAN-----RQLSSREYEGHEDKAAEGHYASQNKEF 553
+ G++ ++ + ++L+T + Q + HE++ E
Sbjct: 1038 TL-----GKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPAT--- 1089
Query: 554 LKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEK----- 608
L E E + L +R +E + + L L AQ +L++ E+ VE+
Sbjct: 1090 LPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERV 1149
Query: 609 ---VEKLQQALTQLQSACEKREQMERRLRTWLER--ELDALRTQQKHGNGQPANMPEYNA 663
+E+ Q L Q + EQ+ R+LR + E L A + Q MP ++
Sbjct: 1150 AQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1209
Query: 664 PALLELVREKEERILALEADMTKWEQ 689
A+ E +R+++ + +E K E+
Sbjct: 1210 QAVREQLRQEQALLEEIERHGEKVEE 1235
Score = 34.7 bits (78), Expect = 0.44
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 22/163 (13%)
Query: 473 EKELQRI-SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSS 531
++ELQR+ +EA E+ + + E L ++R ++E E+ +L + R+E NR L
Sbjct: 2174 DEELQRLKAEATEAARQRSQVEEELF-SVRVQME-ELSKL-------KARIEAENRALIL 2224
Query: 532 REYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQAR 591
R DK + + E +K+ + E A + A+++ R ++ ++ L+ +A
Sbjct: 2225 R------DKDNTQRFLQEEAEKMKQVAE---EAARLSVAAQEAARLRQLAEEDLAQQRAL 2275
Query: 592 VIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLR 634
K+ L+EK V++ +L+ LQ E ++ RRL+
Sbjct: 2276 AEKM---LKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2315
Score = 34.3 bits (77), Expect = 0.57
Identities = 49/196 (25%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 445 VEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKA-MRNK 503
VE +R LHQ ++ + ++ E +L S A + R L A + N
Sbjct: 519 VEAQLGSHRGLHQSIEEFRAKIERARSDEGQL---SPATRGAYRDCLGRLDLQYAKLLNS 575
Query: 504 LEGEIRRL---HDFNRDLRDRLETANRQLSSREYEGHEDK-----AAEGHYASQNKEF-L 554
+ +R L H F L N + D+ A + Y++ +E L
Sbjct: 576 SKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELEL 635
Query: 555 KEKEKLEMELAAVRTASEDH--RRHIEILDQALSNAQARVIKL----EEELREKQAYVEK 608
KEK+ E++ A R EDH R +E AL + +++L E L+E AY +
Sbjct: 636 KEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQF 695
Query: 609 VEKLQQALTQLQSACE 624
+++A QLQ E
Sbjct: 696 FSDVREAEGQLQKLQE 711
Score = 31.2 bits (69), Expect = 4.8
Identities = 41/194 (21%), Positives = 84/194 (43%), Gaps = 29/194 (14%)
Query: 439 ERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKE-----LQRISEAYESLVKSTTKR 493
ER ++ + L E L QE + ++++ ++E Q + +++ S S +R
Sbjct: 2414 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2473
Query: 494 ESLDKAMRNKLE-------GEIRRLHDFNRDLRDRLETANRQL--SSREYEGHEDKAAEG 544
E + + KLE + ++L + + + ++E ++L S E + +A EG
Sbjct: 2474 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2533
Query: 545 HYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQA 604
Q +E ++LE + R+ E+L + + ++ LEE+ R A
Sbjct: 2534 VRRKQ-----EELQQLEQQ----------RRQQEELLAEENQRLREQLQLLEEQHRAALA 2578
Query: 605 YVEKVEKLQQALTQ 618
+ E+V Q A T+
Sbjct: 2579 HSEEVTASQVAATK 2592
Score = 31.2 bits (69), Expect = 4.8
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 16/110 (14%)
Query: 154 QSARQEPQGQEHQV--------DNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQ 205
Q+ +QE QE Q +++++++ Q + E+L E AKAQ R +Q
Sbjct: 2445 QTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ--LREEQ 2502
Query: 206 QQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQ 255
Q+QQQQ +A S E R + A G K E L++L+Q
Sbjct: 2503 QRQQQQMEQERQRLVA------SMEEARRRQHEAEEGVRRKQEELQQLEQ 2546
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,816,535
Number of Sequences: 37866
Number of extensions: 2183405
Number of successful extensions: 18522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 218
Number of HSP's successfully gapped in prelim test: 1158
Number of HSP's that attempted gapping in prelim test: 12489
Number of HSP's gapped (non-prelim): 5330
length of query: 956
length of database: 18,247,518
effective HSP length: 112
effective length of query: 844
effective length of database: 14,006,526
effective search space: 11821507944
effective search space used: 11821507944
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.