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Search of human proteins with 217272865
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217272865 myotubularin related protein 4 [Homo sapiens]
(1195 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217272865 myotubularin related protein 4 [Homo sapiens] 2504 0.0
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 1094 0.0
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 1053 0.0
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 1045 0.0
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 329 8e-90
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 328 1e-89
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 328 1e-89
gi|4557896 myotubularin [Homo sapiens] 327 4e-89
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 303 6e-82
gi|21361759 myotubularin related protein 8 [Homo sapiens] 294 3e-79
gi|225543474 myotubularin related protein 7 [Homo sapiens] 285 2e-76
gi|134142348 myotubularin related protein 6 [Homo sapiens] 269 1e-71
gi|19923424 myotubularin related protein 9 [Homo sapiens] 251 4e-66
gi|29788755 SET binding factor 2 [Homo sapiens] 161 4e-39
gi|239735519 SET binding factor 1 [Homo sapiens] 150 5e-36
gi|124028527 myotubularin related protein 10 [Homo sapiens] 130 7e-30
gi|94721263 myotubularin related protein 12 [Homo sapiens] 103 1e-21
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 102 2e-21
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 102 2e-21
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 75 5e-13
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 75 5e-13
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 74 6e-13
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 73 1e-12
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 73 1e-12
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 72 3e-12
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 72 3e-12
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 72 3e-12
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 69 3e-11
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 68 5e-11
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 68 5e-11
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 2504 bits (6491), Expect = 0.0
Identities = 1195/1195 (100%), Positives = 1195/1195 (100%)
Query: 1 MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRL 60
MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRL
Sbjct: 1 MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRL 60
Query: 61 HIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATAR 120
HIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATAR
Sbjct: 61 HIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATAR 120
Query: 121 PAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHIN 180
PAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHIN
Sbjct: 121 PAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHIN 180
Query: 181 SNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISW 240
SNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISW
Sbjct: 181 SNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISW 240
Query: 241 WGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFDSSLTACSGVEST 300
WGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFDSSLTACSGVEST
Sbjct: 241 WGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFDSSLTACSGVEST 300
Query: 301 AAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVC 360
AAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVC
Sbjct: 301 AAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVC 360
Query: 361 SQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVAL 420
SQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVAL
Sbjct: 361 SQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVAL 420
Query: 421 AKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQL 480
AKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQL
Sbjct: 421 AKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQL 480
Query: 481 LKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKN 540
LKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKN
Sbjct: 481 LKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKN 540
Query: 541 FHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGR 600
FHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGR
Sbjct: 541 FHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGR 600
Query: 601 SLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHCQEVRVGLEPWHSNPEGSETSFVD 660
SLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHCQEVRVGLEPWHSNPEGSETSFVD
Sbjct: 601 SLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHCQEVRVGLEPWHSNPEGSETSFVD 660
Query: 661 SGVGGPQQTVGEVGLPPPLPSSQKDYLSNKPFKSHKSCSPSYKLLNTAVPREMKSNTSDP 720
SGVGGPQQTVGEVGLPPPLPSSQKDYLSNKPFKSHKSCSPSYKLLNTAVPREMKSNTSDP
Sbjct: 661 SGVGGPQQTVGEVGLPPPLPSSQKDYLSNKPFKSHKSCSPSYKLLNTAVPREMKSNTSDP 720
Query: 721 EIKVLEETKGPAPDPSAQDELGRTLDGIGEPPEHCPETEAVSALSKVISNKCDGVCNFPE 780
EIKVLEETKGPAPDPSAQDELGRTLDGIGEPPEHCPETEAVSALSKVISNKCDGVCNFPE
Sbjct: 721 EIKVLEETKGPAPDPSAQDELGRTLDGIGEPPEHCPETEAVSALSKVISNKCDGVCNFPE 780
Query: 781 SSQNSPTGTPQQAQPDSMLGVPSKCVLDHSLSTVCNPPSAACQTPLDPSTDFLNQDPSGS 840
SSQNSPTGTPQQAQPDSMLGVPSKCVLDHSLSTVCNPPSAACQTPLDPSTDFLNQDPSGS
Sbjct: 781 SSQNSPTGTPQQAQPDSMLGVPSKCVLDHSLSTVCNPPSAACQTPLDPSTDFLNQDPSGS 840
Query: 841 VASISHQEQLSSVPDLTHGEEDIGKRGNNRNGQLLENPRFGKMPLELVRKPISQSQISEF 900
VASISHQEQLSSVPDLTHGEEDIGKRGNNRNGQLLENPRFGKMPLELVRKPISQSQISEF
Sbjct: 841 VASISHQEQLSSVPDLTHGEEDIGKRGNNRNGQLLENPRFGKMPLELVRKPISQSQISEF 900
Query: 901 SFLGSNWDSFQGMVTSFPSGEATPRRLLSYGCCSKRPNSKQMRATGPCFGGQWAQREGVK 960
SFLGSNWDSFQGMVTSFPSGEATPRRLLSYGCCSKRPNSKQMRATGPCFGGQWAQREGVK
Sbjct: 901 SFLGSNWDSFQGMVTSFPSGEATPRRLLSYGCCSKRPNSKQMRATGPCFGGQWAQREGVK 960
Query: 961 SPVCSSHSNGHCTGPGGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDV 1020
SPVCSSHSNGHCTGPGGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDV
Sbjct: 961 SPVCSSHSNGHCTGPGGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDV 1020
Query: 1021 IQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSD 1080
IQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSD
Sbjct: 1021 IQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSD 1080
Query: 1081 TEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCG 1140
TEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCG
Sbjct: 1081 TEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCG 1140
Query: 1141 NVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS 1195
NVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS
Sbjct: 1141 NVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS 1195
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 1094 bits (2830), Expect = 0.0
Identities = 611/1240 (49%), Positives = 793/1240 (63%), Gaps = 87/1240 (7%)
Query: 1 MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRL 60
M EE SLE IQA +FP K+L++E+ENLQVPF L GE EF+GRA DA+IA+SNYRL
Sbjct: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
Query: 61 HIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATAR 120
HIKFK+S++NVPL++I+SVE RD+FQLH++CKD KV+RC FSTF+QCQEWL RL+ A
Sbjct: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
Query: 121 PAKPEDLFAFAYHAWCLGL--TEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSH 178
PAK EDLF+FAYHAWC+ + +E++QH LC+PGEH+ R + E+ RMGFD+ N WR+S+
Sbjct: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
Query: 179 INSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEI 238
IN YKLC SYPQ+L+VP WITDKELE+V+SFRSWKRIP V+YRH NGA IARC QPE+
Sbjct: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
Query: 239 SWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTS-----EACDADFDSSLTA 293
SWWGWRNADDE+LV S+AKACA D +R++G LST N + D +FDSSL+
Sbjct: 241 SWWGWRNADDEHLVQSVAKACASD--SRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSN 298
Query: 294 CSGVESTAA-PQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNS 352
SG ES A PQKLLILDARSY AAVANRAKGGGCEC EYYPNCEVVFMGMANIH+IR S
Sbjct: 299 ASGAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRS 358
Query: 353 FQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWD 412
FQ LR +C+QMPDP NWLSALESTKWL HLSV+LK+A+LV + VD++ RPVLVHCSDGWD
Sbjct: 359 FQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWD 418
Query: 413 RTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQ 472
RTPQIVALAK+LLDPYYRT+EGFQVLVE +WLDFGHKF DRCGH EN +D NE+CPVFLQ
Sbjct: 419 RTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQ 478
Query: 473 WLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWA 532
WLD VHQL +QFPC FEFNEAFLVKLVQHTYSCL+GTFL NN ER +++ +RTCSVW+
Sbjct: 479 WLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWS 538
Query: 533 LLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVA 592
LLRAGNK F N LY+ S+ VL+PVCHVR L LW+AVYLP SP T +++ Y +P
Sbjct: 539 LLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGT 598
Query: 593 QSQEFSGRSLDRLPKTRSMDDLLSACDTSSPL-TRTSSDPNLNNHCQEVRVGLEPWHSNP 651
+ L RLPKTRS D+L +ACD + PL +R SDP+LN QE R LE
Sbjct: 599 SPDD---PPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAG 655
Query: 652 EGSETSFVDSGVGGPQQTVG--EVGLPPPLPSSQKDYLSNKPFKSHKSC-SPSYKLLNTA 708
G + DS +G P + G E+ + + Q + + + K P+++
Sbjct: 656 PGEDPLSADS-LGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHR----- 709
Query: 709 VPREMKSNTSDPEIKVLEETKGPAPDPSAQDELGRTLD-GIGEPPEHCPETEAVSALSKV 767
E++ DP ++ +E++ P+ SA +G D +G+ + S+
Sbjct: 710 AGIEIQEGKEDPLLE--KESRRKTPEASA---IGLHQDPELGDAALRSHLDMSWPLFSQG 764
Query: 768 ISNKCDGVCNFPESSQNSPTGTPQ--------------QAQPDSMLGVPSKCVLDHSLST 813
IS + G+ S Q P G + + +++L +P + + S
Sbjct: 765 ISEQQSGLSVLLSSLQVPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQ 824
Query: 814 VCN--PPSAACQT---PLDPSTDFLNQDPSGSVASISHQEQLSSVPDLTHGEEDIGKRGN 868
C+ P +T +D STD L +D V S+S + H + G
Sbjct: 825 SCSLLPSQVPFETRGPNVDSSTDMLVED---KVKSVSGPQ--------GHHRSCLVNSGK 873
Query: 869 NRNGQLLENPRFGKMPLELVRKPISQSQISEFSFLGSNWDSFQGMVTSFPSGEATPRRLL 928
+R Q +E LV +P S + S LGS S + P E L+
Sbjct: 874 DRLPQTMEP---SPSETSLVERPQVGSVVHRTS-LGSTL-SLTRSPCALPLAEC-KEGLV 927
Query: 929 SYGC------CSKRP---NSKQMRAT--GPCFGGQWAQREGVKSPVCS--SHSNGHCTGP 975
G S++P ++ QM T G C G+ + + S S S S+ H
Sbjct: 928 CNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSCSSAHLHS- 986
Query: 976 GGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQE 1035
+ WL SH S +P + P +LDDDG+ TD IQ RLRQIE+G++QE
Sbjct: 987 RNLHHKWLHSH-----SGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQQE 1041
Query: 1036 VEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSE 1095
VE L++QV+EL+ RL+ ++ + D+ D+ T + +S+ + ++ S S + SE
Sbjct: 1042 VETLKKQVQELKSRLESQYLTS-SLHFNGDFGDEVTSIPDSESNLDQNCLSRCSTEIFSE 1100
Query: 1096 ASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIP 1155
ASWE VDK++TE+TRW+PDH+A+HCY CD FWLA R+HHCRNCGNVFC+ CC+ K+P+P
Sbjct: 1101 ASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVP 1160
Query: 1156 DQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS 1195
QQL++P VC SCY + + + + +L KPIA S+
Sbjct: 1161 SQQLFEPSRVCKSCYSSLHPTSSS--IDLELDKPIAATSN 1198
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 1053 bits (2723), Expect = 0.0
Identities = 599/1240 (48%), Positives = 771/1240 (62%), Gaps = 124/1240 (10%)
Query: 1 MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRL 60
M EE SLE IQA +FP K+L++E+ENLQVPF L GE EF+GRA DA+IA+SNYRL
Sbjct: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
Query: 61 HIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATAR 120
HIKFK+S++NVPL++I+SVE RD+FQLH++CKD KV+RC FSTF+QCQEWL RL+ A
Sbjct: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
Query: 121 PAKPEDLFAFAYHAWCLGL--TEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSH 178
PAK EDLF+FAYHAWC+ + +E++QH LC+PGEH+ R + E+ RMGFD+ N WR+S+
Sbjct: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
Query: 179 INSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEI 238
IN YKLC SYPQ+L+VP WITDKELE+V+SFRSWKRIP V+YRH NGA IARC QPE+
Sbjct: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
Query: 239 SWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTS-----EACDADFDSSLTA 293
SWWGWRNADDE+LV S+AKACA D +R++G LST N + D +FDSSL+
Sbjct: 241 SWWGWRNADDEHLVQSVAKACASD--SRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSN 298
Query: 294 CSGVESTAA-PQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNS 352
SG ES A PQKLLILDARSY AAVANRAKGGGCEC EYYPNCEVVFMGMANIH+IR S
Sbjct: 299 ASGAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRS 358
Query: 353 FQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWD 412
FQ LR +C+QMPDP NWLSALESTKWL HLSV+LK+A+LV + VD++ RPVLVHCSDGWD
Sbjct: 359 FQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWD 418
Query: 413 RTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQ 472
RTPQIVALAK+LLDPYYRT+EGFQVLVE +WLDFGHKF DRCGH EN +D NE+CPVFLQ
Sbjct: 419 RTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQ 478
Query: 473 WLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWA 532
WLD VHQL +QFPC FEFNEAFLVKLVQHTYSCL+GTFL NN ER +++ +RTCSVW+
Sbjct: 479 WLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWS 538
Query: 533 LLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVA 592
LLRAGNK F N LY+ S+ VL+PVCHVR L LW+AVYLP SP T +++ Y +P
Sbjct: 539 LLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGT 598
Query: 593 QSQEFSGRSLDRLPKTRSMDDLLSACDTSSPL-TRTSSDPNLNNHCQEVRVGLEPWHSNP 651
+ L RLPKTRS D+L +ACD + PL +R SDP+LN QE R LE
Sbjct: 599 SPDD---PPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAG 655
Query: 652 EGSETSFVDSGVGGPQQTVG--EVGLPPPLPSSQKDYLSNKPFKSHKSC-SPSYKLLNTA 708
G + DS +G P + G E+ + + Q + + + K P+++
Sbjct: 656 PGEDPLSADS-LGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHR----- 709
Query: 709 VPREMKSNTSDPEIKVLEETKGPAPDPSAQDELGRTLD-GIGEPPEHCPETEAVSALSKV 767
E++ DP ++ +E++ P+ SA +G D +G+ + S+
Sbjct: 710 AGIEIQEGKEDPLLE--KESRRKTPEASA---IGLHQDPELGDAALRSHLDMSWPLFSQG 764
Query: 768 ISNKCDGVCNFPESSQNSPTGTPQ--------------QAQPDSMLGVPSKCVLDHSLST 813
IS + G+ S Q P G + + +++L +P + + S
Sbjct: 765 ISEQQSGLSVLLSSLQVPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQ 824
Query: 814 VCN--PPSAACQT---PLDPSTDFLNQDPSGSVASISHQEQLSSVPDLTHGEEDIGKRGN 868
C+ P +T +D STD L +D V S+S + H + G
Sbjct: 825 SCSLLPSQVPFETRGPNVDSSTDMLVED---KVKSVSGPQ--------GHHRSCLVNSGK 873
Query: 869 NRNGQLLENPRFGKMPLELVRKPISQSQISEFSFLGSNWDSFQGMVTSFPSGEATPRRLL 928
+R Q +E LV +P S + S LGS S + P E L+
Sbjct: 874 DRLPQTMEP---SPSETSLVERPQVGSVVHRTS-LGSTL-SLTRSPCALPLAEC-KEGLV 927
Query: 929 SYGC------CSKRP---NSKQMRAT--GPCFGGQWAQREGVKSPVCS--SHSNGHCTGP 975
G S++P ++ QM T G C G+ + + S S S S+ H
Sbjct: 928 CNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSCSSAHLHS- 986
Query: 976 GGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQE 1035
+ WL SH S +P + P +LDDDG+ TD IQ RLRQIE+G++QE
Sbjct: 987 RNLHHKWLHSH-----SGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQQE 1041
Query: 1036 VEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSE 1095
VE L++QV+EL+ RL+ ++ T +G DFG +
Sbjct: 1042 VETLKKQVQELKSRLESQY---------------LTSSLHFNG----DFGDE-------- 1074
Query: 1096 ASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIP 1155
+TRW+PDH+A+HCY CD FWLA R+HHCRNCGNVFC+ CC+ K+P+P
Sbjct: 1075 -----------VMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVP 1123
Query: 1156 DQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS 1195
QQL++P VC SCY + + + + +L KPIA S+
Sbjct: 1124 SQQLFEPSRVCKSCYSSLHPTSSS--IDLELDKPIAATSN 1161
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 1045 bits (2703), Expect = 0.0
Identities = 599/1249 (47%), Positives = 771/1249 (61%), Gaps = 133/1249 (10%)
Query: 1 MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRL 60
M EE SLE IQA +FP K+L++E+ENLQVPF L GE EF+GRA DA+IA+SNYRL
Sbjct: 1 MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRL 60
Query: 61 HIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATAR 120
HIKFK+S++NVPL++I+SVE RD+FQLH++CKD KV+RC FSTF+QCQEWL RL+ A
Sbjct: 61 HIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRP 120
Query: 121 PAKPEDLFAFAYHAWCLGL--TEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSH 178
PAK EDLF+FAYHAWC+ + +E++QH LC+PGEH+ R + E+ RMGFD+ N WR+S+
Sbjct: 121 PAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISN 180
Query: 179 INSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEI 238
IN YKLC SYPQ+L+VP WITDKELE+V+SFRSWKRIP V+YRH NGA IARC QPE+
Sbjct: 181 INEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240
Query: 239 SWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTS-----EACDADFDSSLTA 293
SWWGWRNADDE+LV S+AKACA D +R++G LST N + D +FDSSL+
Sbjct: 241 SWWGWRNADDEHLVQSVAKACASD--SRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSN 298
Query: 294 CSGVESTAA-PQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNS 352
SG ES A PQKLLILDARSY AAVANRAKGGGCEC EYYPNCEVVFMGMANIH+IR S
Sbjct: 299 ASGAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRS 358
Query: 353 FQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWD 412
FQ LR +C+QMPDP NWLSALESTKWL HLSV+LK+A+LV + VD++ RPVLVHCSDGWD
Sbjct: 359 FQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWD 418
Query: 413 RTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQ 472
RTPQIVALAK+LLDPYYRT+EGFQVLVE +WLDFGHKF DRCGH EN +D NE+CPVFLQ
Sbjct: 419 RTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQ 478
Query: 473 WLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWA 532
WLD VHQL +QFPC FEFNEAFLVKLVQHTYSCL+GTFL NN ER +++ +RTCSVW+
Sbjct: 479 WLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWS 538
Query: 533 LLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVA 592
LLRAGNK F N LY+ S+ VL+PVCHVR L LW+AVYLP SP T +++ Y +P
Sbjct: 539 LLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGT 598
Query: 593 QSQEFSGRSLDRLPKTRSMDDLLSACDTSSPL-TRTSSDPNLNNHCQEVRVGLEPWHSNP 651
+ L RLPKTRS D+L +ACD + PL +R SDP+LN QE R LE
Sbjct: 599 SPDD---PPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAG 655
Query: 652 EGSETSFVDSGVGGPQQTVG--EVGLPPPLPSSQKDYLSNKPFKSHKSC-SPSYKLLNTA 708
G + DS +G P + G E+ + + Q + + + K P+++
Sbjct: 656 PGEDPLSADS-LGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHR----- 709
Query: 709 VPREMKSNTSDPEIKVLEETKGPAPDPSAQDELGRTLD-GIGEPPEHCPETEAVSALSKV 767
E++ DP ++ +E++ P+ SA +G D +G+ + S+
Sbjct: 710 AGIEIQEGKEDPLLE--KESRRKTPEASA---IGLHQDPELGDAALRSHLDMSWPLFSQG 764
Query: 768 ISNKCDGVCNFPESSQNSPTGTPQ--------------QAQPDSMLGVPSKCVLDHSLST 813
IS + G+ S Q P G + + +++L +P + + S
Sbjct: 765 ISEQQSGLSVLLSSLQVPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQ 824
Query: 814 VCN--PPSAACQT---PLDPSTDFLNQDPSGSVASISHQEQLSSVPDLTHGEEDIGKRGN 868
C+ P +T +D STD L +D V S+S + H + G
Sbjct: 825 SCSLLPSQVPFETRGPNVDSSTDMLVED---KVKSVSGPQ--------GHHRSCLVNSGK 873
Query: 869 NRNGQLLENPRFGKMPLELVRKPISQSQISEFSFLGSNWDSFQGMVTSFPSGEATPRRLL 928
+R Q +E LV +P S + S LGS S + P E L+
Sbjct: 874 DRLPQTMEP---SPSETSLVERPQVGSVVHRTS-LGSTL-SLTRSPCALPLAEC-KEGLV 927
Query: 929 SYGC------CSKRP---NSKQMRAT--GPCFGGQWAQREGVKSPVCS--SHSNGHCTGP 975
G S++P ++ QM T G C G+ + + S S S S+ H
Sbjct: 928 CNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSCSSAHLHS- 986
Query: 976 GGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQE 1035
+ WL SH S +P + P +LDDDG+ TD IQ RLRQIE+G++QE
Sbjct: 987 RNLHHKWLHSH-----SGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQQE 1041
Query: 1036 VEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSE 1095
VE L++QV+EL+ RL+ ++ T +G DFG +
Sbjct: 1042 VETLKKQVQELKSRLESQY---------------LTSSLHFNG----DFGDE-------- 1074
Query: 1096 ASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCR---------NCGNVFCAG 1146
+TRW+PDH+A+HCY CD FWLA R+HHCR NCGNVFC+
Sbjct: 1075 -----------VMTRWLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSS 1123
Query: 1147 CCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS 1195
CC+ K+P+P QQL++P VC SCY + + + + +L KPIA S+
Sbjct: 1124 CCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSS--IDLELDKPIAATSN 1170
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 329 bits (844), Expect = 8e-90
Identities = 205/583 (35%), Positives = 303/583 (51%), Gaps = 83/583 (14%)
Query: 16 DLFPPKELVKEEEN----LQVPFTVLQGEGVEFLGR----------AADALIAISNYRLH 61
D F P V E N ++ P +L GE ++ + + A + ++NYRL+
Sbjct: 55 DNFSPDLRVLRESNKLAEMEEP-PLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLY 113
Query: 62 IKFKDS----VINVPLRMIDSVES--------RDMFQLHISCKDSKVVR-CHFSTFKQCQ 108
K + V++ L +I+ VE + + L CKD + +R H + +
Sbjct: 114 FKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRR 173
Query: 109 EWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGF 168
L + + LFAF Y + L P E R G
Sbjct: 174 SIFENLMKYAFPVSNNLPLFAFEYKE-----VFPENGWKLYDP--------LLEYRRQGI 220
Query: 169 DLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGA 228
++ WR++ IN Y+LC +YP L+VP I D+EL+ VASFRS RIPV+ + H + A
Sbjct: 221 PNES-WRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQA 279
Query: 229 AIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFD 288
I RCSQP + G R+ +DE + +I
Sbjct: 280 TITRCSQPMVGVSGKRSKEDEKYLQAI--------------------------------- 306
Query: 289 SSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHA 348
++S A K+ I DAR AVAN+AKGGG E E+ Y N E+VF+ + NIH
Sbjct: 307 --------MDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHV 358
Query: 349 IRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCS 408
+R S + L+ + + ++WLS LEST WL+H+ ++L A+ +A+ V+ V+VHCS
Sbjct: 359 MRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCS 418
Query: 409 DGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCP 468
DGWDRT Q+ +LA ++LD YYRT+ GF+VLVE +WL FGH+F R GH + ++ P
Sbjct: 419 DGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSP 478
Query: 469 VFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTC 528
VFLQ++D V Q+ +QFP FEFNE FL+ ++ H YSCL+GTFL N+ +R K N+ KRT
Sbjct: 479 VFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTV 538
Query: 529 SVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
S+W+ + + ++F N LY S+ VL+PV +R L LW Y+
Sbjct: 539 SLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 581
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 328 bits (842), Expect = 1e-89
Identities = 195/537 (36%), Positives = 286/537 (53%), Gaps = 68/537 (12%)
Query: 48 AADALIAISNYRLHIKFKDS----VINVPLRMIDSVES--------RDMFQLHISCKDSK 95
A + ++NYRL+ K + V++ L +I+ VE + + L CKD +
Sbjct: 28 AVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIR 87
Query: 96 VVR-CHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEH 154
+R H + + L + + LFAF Y + L P
Sbjct: 88 NLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKE-----VFPENGWKLYDP--- 139
Query: 155 IRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWK 214
E R G ++ WR++ IN Y+LC +YP L+VP I D+EL+ VASFRS
Sbjct: 140 -----LLEYRRQGIPNES-WRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRG 193
Query: 215 RIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGSLST 274
RIPV+ + H + A I RCSQP + G R+ +DE + +I
Sbjct: 194 RIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAI------------------- 234
Query: 275 GNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYP 334
++S A K+ I DAR AVAN+AKGGG E E+ Y
Sbjct: 235 ----------------------MDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQ 272
Query: 335 NCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVAN 394
N E+VF+ + NIH +R S + L+ + + ++WLS LEST WL+H+ ++L A+ +A+
Sbjct: 273 NAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIAD 332
Query: 395 TVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRC 454
V+ V+VHCSDGWDRT Q+ +LA ++LD YYRT+ GF+VLVE +WL FGH+F R
Sbjct: 333 KVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRV 392
Query: 455 GHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANN 514
GH + ++ PVFLQ++D V Q+ +QFP FEFNE FL+ ++ H YSCL+GTFL N+
Sbjct: 393 GHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNS 452
Query: 515 PCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
+R K N+ KRT S+W+ + + ++F N LY S+ VL+PV +R L LW Y+
Sbjct: 453 EQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 328 bits (842), Expect = 1e-89
Identities = 195/537 (36%), Positives = 286/537 (53%), Gaps = 68/537 (12%)
Query: 48 AADALIAISNYRLHIKFKDS----VINVPLRMIDSVES--------RDMFQLHISCKDSK 95
A + ++NYRL+ K + V++ L +I+ VE + + L CKD +
Sbjct: 28 AVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIR 87
Query: 96 VVR-CHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEH 154
+R H + + L + + LFAF Y + L P
Sbjct: 88 NLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKE-----VFPENGWKLYDP--- 139
Query: 155 IRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWK 214
E R G ++ WR++ IN Y+LC +YP L+VP I D+EL+ VASFRS
Sbjct: 140 -----LLEYRRQGIPNES-WRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRG 193
Query: 215 RIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGSLST 274
RIPV+ + H + A I RCSQP + G R+ +DE + +I
Sbjct: 194 RIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAI------------------- 234
Query: 275 GNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYP 334
++S A K+ I DAR AVAN+AKGGG E E+ Y
Sbjct: 235 ----------------------MDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQ 272
Query: 335 NCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVAN 394
N E+VF+ + NIH +R S + L+ + + ++WLS LEST WL+H+ ++L A+ +A+
Sbjct: 273 NAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIAD 332
Query: 395 TVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRC 454
V+ V+VHCSDGWDRT Q+ +LA ++LD YYRT+ GF+VLVE +WL FGH+F R
Sbjct: 333 KVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRV 392
Query: 455 GHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANN 514
GH + ++ PVFLQ++D V Q+ +QFP FEFNE FL+ ++ H YSCL+GTFL N+
Sbjct: 393 GHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNS 452
Query: 515 PCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
+R K N+ KRT S+W+ + + ++F N LY S+ VL+PV +R L LW Y+
Sbjct: 453 EQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 327 bits (838), Expect = 4e-89
Identities = 212/609 (34%), Positives = 311/609 (51%), Gaps = 94/609 (15%)
Query: 53 IAISNYRLHIKFKDS----VINVPLRMIDSVES--------RDMFQLHISCKDSKVVRCH 100
+ I+NYRL+++ ++ +++VPL +I +E + + L I+CKD + +R
Sbjct: 63 VYITNYRLYLRSLETDSSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKDMRNLR-- 120
Query: 101 FSTFKQCQEWLSR------LSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTH---LCQP 151
F QE SR L+R A LFAF L EE + + P
Sbjct: 121 ---FALKQEGHSRRDMFEILTRYAFPLAHSLPLFAF--------LNEEKFNVDGWTVYNP 169
Query: 152 GEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFR 211
E R R G + WR++ IN Y+LC +YP L+VP +D +L VA+FR
Sbjct: 170 VEEYR--------RQGLPNHH-WRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFR 220
Query: 212 SWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGS 271
S RIPV+ + H N I RCSQP + G RN DDE + I R T
Sbjct: 221 SRNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVI----------RETNKQ 270
Query: 272 LSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEE 331
+S KL I DAR AVAN+A GGG E ++
Sbjct: 271 IS-------------------------------KLTIYDARPSVNAVANKATGGGYESDD 299
Query: 332 YYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVL 391
Y N E+ F+ + NIH +R S + ++ + + S+WLS+LEST WL+H+ ++L A+
Sbjct: 300 AYHNAELFFLDIHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQ 359
Query: 392 VANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFG 451
VA+ V VLVHCSDGWDRT Q+ +LA ++LD +YR++EGF++LV+ +W+ FGHKF
Sbjct: 360 VADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFA 419
Query: 452 DRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFL 511
R GH + ++ P+FLQ++D V Q+ KQFP FEFNE FL+ ++ H YSC +GTFL
Sbjct: 420 SRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFL 479
Query: 512 ANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
N RE++ + +RT S+W+L+ + + F N YT + VL+PV +R L LW Y+
Sbjct: 480 FNCESARERQKVTERTVSLWSLINSNKEKFKNPFYTKEINRVLYPVASMRHLELWVNYYI 539
Query: 572 PASSPCTLGEEN--MDLYLSPVAQSQEFSGRSLDRLPKTRSMDDLLSACDTSSPLTRTSS 629
+ + N Y+ +A E+ R L+ L L ++ S P T SS
Sbjct: 540 RWNPRIKQQQPNPVEQRYMELLALRDEYIKR-LEEL-------QLANSAKLSDPPTSPSS 591
Query: 630 DPNLNNHCQ 638
+ H Q
Sbjct: 592 PSQMMPHVQ 600
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 303 bits (776), Expect = 6e-82
Identities = 181/568 (31%), Positives = 297/568 (52%), Gaps = 71/568 (12%)
Query: 44 FLGRAADALIAISNYRLHIKFKDS----VINVPLRMIDSVES-------RDMFQLHISCK 92
F+G A + +++++L+ K + +++VPL +I VE + + I CK
Sbjct: 119 FMG-AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCK 177
Query: 93 DSKVVRCHFSTFKQCQEWLSRLSRATARP-AKPEDLFAFAYHAWCLGLTEEDQHTHLCQP 151
D + +R + +Q + + A P + + LFAF+Y +E + +
Sbjct: 178 DMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSY--------KEKFPINGWKV 229
Query: 152 GEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFR 211
+ + +E R G ++ W++S INSNY+ C +YP ++VP + D +L VA+FR
Sbjct: 230 YDPV-----SEYKRQGLPNES-WKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFR 283
Query: 212 SWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGS 271
+ R+PV+ + H + A I RCSQP + R +DE + +I
Sbjct: 284 AKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTI---------------- 327
Query: 272 LSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEE 331
+++ A KL+I DAR + A N+ KGGG E E
Sbjct: 328 -------------------------MDANAQSHKLIIFDARQNSVADTNKTKGGGYESES 362
Query: 332 YYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVL 391
YPN E+VF+ + NIH +R S + L+ + D + WLS ++ T WL+++ ++L AV
Sbjct: 363 AYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRMLLAGAVR 422
Query: 392 VANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFG 451
+A+ ++ V+VHCSDGWDRT Q+ +LA ++LD YYRT++GF+ LVE +W+ FGH+F
Sbjct: 423 IADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFA 482
Query: 452 DRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFL 511
R GH + ++ P+FLQ++D V Q+ +QFP FEFNE FL+ ++ H YSCL+GTFL
Sbjct: 483 LRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFL 542
Query: 512 ANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
N +R K ++Y +T S+W+ + + F N + + VL+PV + L LW Y+
Sbjct: 543 CNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVASLSHLELWVNYYV 602
Query: 572 ---PASSPCTLGEENMDLYLSPVAQSQE 596
P P +N+ L+ A+ Q+
Sbjct: 603 RWNPRMRPQMPIHQNLKELLAVRAELQK 630
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 294 bits (753), Expect = 3e-79
Identities = 175/486 (36%), Positives = 257/486 (52%), Gaps = 57/486 (11%)
Query: 87 LHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHT 146
L + CK+ +V + C E L + + +PA PEDL+AF+Y+ E
Sbjct: 70 LTLRCKNFRVAHFVLDSDLVCHEVYISLLKLS-QPALPEDLYAFSYNPKSSKEMRESGWK 128
Query: 147 HLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELEN 206
L P ++ RMG +N W ++ N NY++C +YP +++VP +T +
Sbjct: 129 -LIDP--------ISDFGRMGIPNRN-WTITDANRNYEICSTYPPEIVVPKSVTLGTVVG 178
Query: 207 VASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTR 266
+ FRS +R+PV+ Y + N AAI RCSQP +S + R DDE L+ +I++ +PG+
Sbjct: 179 SSKFRSKERVPVLSYLYKENNAAICRCSQP-LSGFYTRCVDDELLLEAISQT---NPGS- 233
Query: 267 ATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGG 326
Q + ++D R A+ANRA G G
Sbjct: 234 -------------------------------------QFMYVVDTRPKLNAMANRAAGKG 256
Query: 327 CECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCS-QMPDPSNWLSALESTKWLQHLSVM 385
E E+ Y N FMG+ NIH +R+S Q L VC + P S +LS LES+ WL+H+ +
Sbjct: 257 YENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAI 316
Query: 386 LKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLD 445
+ A + + V E VLVHCSDGWDRT Q+ ++A ILLDP+YRT +G +L+E +W+
Sbjct: 317 MDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWIS 376
Query: 446 FGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSC 505
GHKF RCGH + D E P+F Q+LD + QL++QFPC FEFNE FL+++ H +SC
Sbjct: 377 MGHKFSQRCGHLDG--DSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSC 434
Query: 506 LYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDM-VLHPVCHVRALH 564
+G FL N +RE +Y++T SVW L +F N LY + VL+P +
Sbjct: 435 QFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQ 494
Query: 565 LWTAVY 570
W +Y
Sbjct: 495 FWCGMY 500
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 285 bits (728), Expect = 2e-76
Identities = 171/461 (37%), Positives = 252/461 (54%), Gaps = 56/461 (12%)
Query: 87 LHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHT 146
L I CK+ ++++ + C + L R ARP K E+L+ F+++ L E +Q
Sbjct: 70 LLIRCKNFQIIQLIIPQERDCHDVYISLIRL-ARPVKYEELYCFSFNPM-LDKEEREQGW 127
Query: 147 HLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELEN 206
L E E RMG + W++S +N +Y++C SYP +L VP T +
Sbjct: 128 VLIDLSE--------EYTRMGLP-NHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVG 178
Query: 207 VASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTR 266
+ FRS +R PV+ Y + N A+I R SQP +S + R +DE ++ +I KA +PG+
Sbjct: 179 SSKFRSRRRFPVLSYYYKDNHASICRSSQP-LSGFSARCLEDEQMLQAIRKA---NPGS- 233
Query: 267 ATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGG 326
DF + ++D R A+ANRA G G
Sbjct: 234 -------------------DF------------------VYVVDTRPKLNAMANRAAGKG 256
Query: 327 CECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCS-QMPDPSNWLSALESTKWLQHLSVM 385
E E+ Y N + F+G+ NIH +RNS Q + VC + P S++L LE++ WL+H+ +
Sbjct: 257 YENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAI 316
Query: 386 LKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLD 445
+ A + +A V EG VLVHCSDGWDRT Q+ ++A +LLDP+YRTL+GF VL+E DW+
Sbjct: 317 MDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWIS 376
Query: 446 FGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSC 505
FGHKF R G+ + D E PV Q+++ V QL++QFPC FEFNE FL+ + H YSC
Sbjct: 377 FGHKFNHRYGNLDG--DPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSC 434
Query: 506 LYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLY 546
+G FL N+ ER + I +RT S+WA L ++ N L+
Sbjct: 435 QFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLF 475
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 269 bits (687), Expect = 1e-71
Identities = 169/487 (34%), Positives = 254/487 (52%), Gaps = 58/487 (11%)
Query: 87 LHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHT 146
L I CK+ + V + C + + L + + + AK EDL+AF+Y+ + +
Sbjct: 68 LVIQCKNFRTVHFIVPRERDCHDIYNSLLQLS-KQAKYEDLYAFSYNP-------KQNDS 119
Query: 147 HLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELEN 206
Q + I +E + RMG + W++S N +YK+C +YP++L VP + +
Sbjct: 120 ERLQGWQLIDLAEEYK--RMGVPNSH-WQLSDANRDYKICETYPRELYVPRIASKPIIVG 176
Query: 207 VASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTR 266
+ FRS R PV+ Y H AAI RCSQP +S + R +DE+L+ +I+KA ++
Sbjct: 177 SSKFRSKGRFPVLSYYHQDKEAAICRCSQP-LSGFSARCLEDEHLLQAISKANPVN---- 231
Query: 267 ATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGG 326
+ + ++D R A+ANRA G G
Sbjct: 232 -------------------------------------RYMYVMDTRPKLNAMANRAAGKG 254
Query: 327 CECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMP-DPSNWLSALESTKWLQHLSVM 385
E E+ Y N F+G+ NIH +R+S Q L V +++ S LES+ WL+H+ +
Sbjct: 255 YENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAV 314
Query: 386 LKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLD 445
+ AA+ +A + E VLVHCSDGWDRT Q+ +L +LLD YYRT++GF VL+E DW+
Sbjct: 315 MDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWIS 374
Query: 446 FGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSC 505
FGHKF +RCG + D E PVF Q+L+ V L +QFP FEF+EAFL+++ +H +SC
Sbjct: 375 FGHKFSERCGQLDG--DPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSC 432
Query: 506 LYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSD--MVLHPVCHVRAL 563
+G FL N ERE+ + ++T S+W L K + N LY+ S VL P
Sbjct: 433 QFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFNF 492
Query: 564 HLWTAVY 570
W +Y
Sbjct: 493 KFWRNMY 499
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 251 bits (640), Expect = 4e-66
Identities = 165/509 (32%), Positives = 248/509 (48%), Gaps = 77/509 (15%)
Query: 76 IDSVESRDMFQLH---ISCKDSKVVRCHFSTFKQCQ------EWLSRLSRATARPAKPED 126
ID+++ R + L I CKD ++++ ++C E LS L T
Sbjct: 55 IDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITL------- 107
Query: 127 LFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLC 186
++ F Y + E+ H+ L + QE EL + WR+S++N + +C
Sbjct: 108 MYPFFYRPM-FEVIEDGWHSFLPE--------QEFELYSSA---TSEWRLSYVNKEFAVC 155
Query: 187 PSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNA 246
PSYP + VP I D+ L VA+FR R PV+ Y H +NG I R QP G R
Sbjct: 156 PSYPPIVTVPKSIDDEALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCK 215
Query: 247 DDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKL 306
+DE L+ + +A G R
Sbjct: 216 EDEKLINATLRA-----GKRG--------------------------------------- 231
Query: 307 LILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCS-QMPD 365
I+D RS A RAKGGG E E +YP + + H ++ S L C+ Q +
Sbjct: 232 YIIDTRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHN 291
Query: 366 PSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILL 425
WLS LE++ WL H+ +L A L A +DREG +L+H ++G D T Q+ +LA+I+L
Sbjct: 292 MDRWLSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIIL 351
Query: 426 DPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVE-DQNEQCPVFLQWLDSVHQLLKQF 484
+P RT+ GF+ L+E +WL GH F RC Q + PVFL +LD V Q+L+QF
Sbjct: 352 EPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQF 411
Query: 485 PCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNK--NFH 542
PC FEFNE FL+ L +H Y+ +GTFL NN ER K + ++T S+W+ + ++ F
Sbjct: 412 PCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFT 471
Query: 543 NFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
N L+ ++++V+ P ++L LW ++L
Sbjct: 472 NPLF-EANNLVIWPSVAPQSLPLWEGIFL 499
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 161 bits (407), Expect = 4e-39
Identities = 134/448 (29%), Positives = 201/448 (44%), Gaps = 60/448 (13%)
Query: 174 WRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARC 233
+R++ N Y LC SYP L+VP + D L VA R+PVV +++ R+G + R
Sbjct: 1138 FRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRS 1197
Query: 234 -------------------SQPEISWWGWRNADDE-YL-----------------VTSIA 256
+ P S + + E YL ++
Sbjct: 1198 GGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLTVR 1257
Query: 257 KACALDPGTRATGGSLSTGNNDTSEACD--ADFDSSLTACSGVESTAAPQKLLILDARSY 314
A AL PG A+ S + + + D A + S S+ +LL A Y
Sbjct: 1258 PAFALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSSYLQNQLLKRQAALY 1317
Query: 315 TAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVC--SQMPDPSN--WL 370
++ + E + NCE V + I ++ SF+ L C S +P S +L
Sbjct: 1318 IFGEKSQLRNFKVE---FALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFL 1374
Query: 371 SALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYR 430
AL ++W L +++ AV+V+ ++ G VLV +GWD T Q+ +L ++L DP+YR
Sbjct: 1375 KALGDSEWFPQLHRIMQLAVVVSEVLEN-GSSVLVCLEEGWDITAQVTSLVQLLSDPFYR 1433
Query: 431 TLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEF 490
TLEGFQ+LVE +WL FGHKF R N + PVFLQ+LD VHQ+ Q+P FEF
Sbjct: 1434 TLEGFQMLVEKEWLSFGHKFSQRSSLTLNCQGSG-FAPVFLQFLDCVHQVHNQYPTEFEF 1492
Query: 491 NEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIY---------KRTCSVWALLRAGNKN- 540
N +L L H S + TFL ++ ER + K+ +W + +K
Sbjct: 1493 NLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGEKHAKKGVCIWECIDRMHKRS 1552
Query: 541 --FHNFLYTPSSDMVLHPVCHVRALHLW 566
F N+LY+P L P +V +L W
Sbjct: 1553 PIFFNYLYSPLEIEALKPNVNVSSLKKW 1580
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 150 bits (380), Expect = 5e-36
Identities = 94/248 (37%), Positives = 138/248 (55%), Gaps = 20/248 (8%)
Query: 337 EVVFMGMANIHAIRNSFQYLRAVC-----SQMPDPSNWLSALESTKWLQHLSVMLKAAVL 391
E+V + + ++ SF+ L C + P P+++L +LE ++WL + +L+ +VL
Sbjct: 1373 ELVPIEVFEARQVKASFKKLLKACVPGCPAAEPSPASFLRSLEDSEWLIQIHKLLQVSVL 1432
Query: 392 VANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFG 451
V +D G VLV DGWD T Q+V+L ++L DP+YRTLEGF++LVE +WL FGH+F
Sbjct: 1433 VVELLD-SGSSVLVGLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFS 1491
Query: 452 DRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFL 511
R H + PVFLQ+LD VHQ+ QFP FEF++ +L L H S + TFL
Sbjct: 1492 HRGAH-TLAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHVSRRFRTFL 1550
Query: 512 ANNPCER-EKRNIYKR--------TC-SVWALLRAGNKN---FHNFLYTPSSDMVLHPVC 558
++ ER E +Y+ C SVW + +K FHN++Y P VL P
Sbjct: 1551 LDSDYERIELGLLYEEKGERRGQVPCRSVWEYVDRLSKRTPVFHNYMYAPEDAEVLRPYS 1610
Query: 559 HVRALHLW 566
+V L +W
Sbjct: 1611 NVSNLKVW 1618
Score = 44.3 bits (103), Expect = 7e-04
Identities = 22/59 (37%), Positives = 33/59 (55%)
Query: 174 WRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIAR 232
+R+S +N Y +C SYP L+VP + D L+ V+ R PVV +R R+ A + R
Sbjct: 1150 FRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLR 1208
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 130 bits (327), Expect = 7e-30
Identities = 64/183 (34%), Positives = 113/183 (61%), Gaps = 6/183 (3%)
Query: 343 MANIHAIRNSFQYLRAVCSQMP---DPSNWLSALESTKWLQHLSVMLKAAVLVANTVDRE 399
+ NI ++ +F L+ +C P WLS+LE+T+WL+++ LK + + ++ +
Sbjct: 336 LPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESK 395
Query: 400 GRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQEN 459
V++ +G D + + +L +++LDPY+RT+ GFQ L++ +W+ G++F DRC H +
Sbjct: 396 HLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKR 455
Query: 460 VEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCERE 519
E ++ P+FL +LD+ QLL+Q+P FEF+E +L L T L+GTFL N+P +R
Sbjct: 456 SE---KESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRV 512
Query: 520 KRN 522
K++
Sbjct: 513 KQS 515
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 103 bits (256), Expect = 1e-21
Identities = 54/151 (35%), Positives = 85/151 (56%), Gaps = 2/151 (1%)
Query: 369 WLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPY 428
W S LES+ WL + LK A+ + ++ + VL+ + D I +L ++++DP+
Sbjct: 353 WFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPH 412
Query: 429 YRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLF 488
RT GFQ L++ +W+ GH F DRC H ++ E+ PVFL +LD V QL+ Q P F
Sbjct: 413 CRTRIGFQSLIQKEWVMGGHCFLDRCNHLR--QNDKEEVPVFLLFLDCVWQLVHQHPPAF 470
Query: 489 EFNEAFLVKLVQHTYSCLYGTFLANNPCERE 519
EF E +L L Y ++ TF N+P +++
Sbjct: 471 EFTETYLTVLSDSLYIPIFSTFFFNSPHQKD 501
Score = 31.2 bits (69), Expect = 6.2
Identities = 36/151 (23%), Positives = 61/151 (40%), Gaps = 11/151 (7%)
Query: 86 QLHISCKDSKVVR--CHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEED 143
+L I CKD +V + ++ ++ + +S + T P + LF F+Y T D
Sbjct: 138 KLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTD 197
Query: 144 QHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKE 203
H E E + + V +N YK+C P +VP + +
Sbjct: 198 PKNHTVMFDTLKDWCWELERTKGNMKYKAV----SVNEGYKVCERLPAYFVVPTPLPE-- 251
Query: 204 LENVASFRSWKRIPVVVYRHLRNGAAIARCS 234
ENV F+ IP+ + NG+A+ + S
Sbjct: 252 -ENVQRFQG-HGIPIWCW-SCHNGSALLKMS 279
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 102 bits (254), Expect = 2e-21
Identities = 73/197 (37%), Positives = 100/197 (50%), Gaps = 24/197 (12%)
Query: 356 LRAVCSQMPDPS----NWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGW 411
LRA+C +PD S WLSALE T+WL ++ L+ A ++ V R V++
Sbjct: 322 LRALC--LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDR 379
Query: 412 DRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFL 471
D + +L ++L P RTL GFQ LV+ +W+ GH F R G +E+ PVFL
Sbjct: 380 DLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGG----TGASEEAPVFL 435
Query: 472 QWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVW 531
+LD V QLL+QFP FEF+E FL+ L TFL N P ER K
Sbjct: 436 LFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGK----------- 484
Query: 532 ALLRAGNKNFHNFLYTP 548
++G N + +YTP
Sbjct: 485 ---QSGQLNSYTQVYTP 498
Score = 31.2 bits (69), Expect = 6.2
Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 174 WRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARC 233
WRVS +N + + S P+ VP I D E+ R P + + H G+ + RC
Sbjct: 214 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHH-PGGSDLLRC 272
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 102 bits (254), Expect = 2e-21
Identities = 73/197 (37%), Positives = 100/197 (50%), Gaps = 24/197 (12%)
Query: 356 LRAVCSQMPDPS----NWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGW 411
LRA+C +PD S WLSALE T+WL ++ L+ A ++ V R V++
Sbjct: 250 LRALC--LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDR 307
Query: 412 DRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFL 471
D + +L ++L P RTL GFQ LV+ +W+ GH F R G +E+ PVFL
Sbjct: 308 DLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGG----TGASEEAPVFL 363
Query: 472 QWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVW 531
+LD V QLL+QFP FEF+E FL+ L TFL N P ER K
Sbjct: 364 LFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGK----------- 412
Query: 532 ALLRAGNKNFHNFLYTP 548
++G N + +YTP
Sbjct: 413 ---QSGQLNSYTQVYTP 426
Score = 31.2 bits (69), Expect = 6.2
Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 174 WRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARC 233
WRVS +N + + S P+ VP I D E+ R P + + H G+ + RC
Sbjct: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHH-PGGSDLLRC 200
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 74.7 bits (182), Expect = 5e-13
Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query: 1060 AEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASH 1119
A+P + + ++ + ES+ F + + + E + + + T WVPD A +
Sbjct: 695 ADPQVSFNSNYIDI-ESNSEGGSSFVTANEDSVPENTCKEGLVLGQKQPT-WVPDSEAPN 752
Query: 1120 CYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRAR 1179
C NC +F KRRHHCR CG VFC CC+ K + Q L VC CYE I ++A
Sbjct: 753 CMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCYETISKAQAF 810
Query: 1180 ELM 1182
E M
Sbjct: 811 ERM 813
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 74.7 bits (182), Expect = 5e-13
Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query: 1060 AEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASH 1119
A+P + + ++ + ES+ F + + + E + + + T WVPD A +
Sbjct: 695 ADPQVSFNSNYIDI-ESNSEGGSSFVTANEDSVPENTCKEGLVLGQKQPT-WVPDSEAPN 752
Query: 1120 CYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRAR 1179
C NC +F KRRHHCR CG VFC CC+ K + Q L VC CYE I ++A
Sbjct: 753 CMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCYETISKAQAF 810
Query: 1180 ELM 1182
E M
Sbjct: 811 ERM 813
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 74.3 bits (181), Expect = 6e-13
Identities = 36/82 (43%), Positives = 48/82 (58%), Gaps = 6/82 (7%)
Query: 1093 LSEASWEPVDKKETEVTR----WVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCC 1148
LSE+ + D KE W+ D A+HC C+ EF L+KR+HHCRNCG +FC C
Sbjct: 550 LSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACS 609
Query: 1149 HLKLPIPDQQLYDPVLVCNSCY 1170
+LP+P PV VC+SC+
Sbjct: 610 DNELPLPSSP--KPVRVCDSCH 629
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 73.2 bits (178), Expect = 1e-12
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 24/172 (13%)
Query: 1015 PFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLK 1074
P P + +++ GY+ E + + R + D R A PAE T L
Sbjct: 122 PHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFD-RKDNAHPAE--------VTALG 172
Query: 1075 ESDGSDTEDFGSDHSEDCLSEA-----SWEPVDKK-ETEVTRWVPDHMASHCYNCDCEFW 1128
S DHS + ++ SW D+ + WV D C C F
Sbjct: 173 IS---------KDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFS 223
Query: 1129 LAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARE 1180
L +RRHHCRNCG +FC C + I ++ PV VC +CY ++Q R E
Sbjct: 224 LTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSE 275
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 73.2 bits (178), Expect = 1e-12
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 24/172 (13%)
Query: 1015 PFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLK 1074
P P + +++ GY+ E + + R + D R A PAE T L
Sbjct: 3367 PHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFD-RKDNAHPAE--------VTALG 3417
Query: 1075 ESDGSDTEDFGSDHSEDCLSEA-----SWEPVDKK-ETEVTRWVPDHMASHCYNCDCEFW 1128
S DHS + ++ SW D+ + WV D C C F
Sbjct: 3418 IS---------KDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFS 3468
Query: 1129 LAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARE 1180
L +RRHHCRNCG +FC C + I ++ PV VC +CY ++Q R E
Sbjct: 3469 LTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSE 3520
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sapiens]
Length = 600
Score = 72.0 bits (175), Expect = 3e-12
Identities = 41/137 (29%), Positives = 69/137 (50%), Gaps = 20/137 (14%)
Query: 1034 QEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCL 1093
Q+VE L++++RELQ D + + + E ++ G S+ L
Sbjct: 472 QQVEGLKKELRELQ-----------------DEKAELQKICEEQEQALQEMGLHLSQSKL 514
Query: 1094 SEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLP 1153
+ V++ + W+ D A+HC C+ EF +++R+HHCRNCG++FC C +L
Sbjct: 515 KMEDIKEVNQA-LKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELA 573
Query: 1154 IPDQQLYDPVLVCNSCY 1170
+P PV VC+SC+
Sbjct: 574 LPSYP--KPVRVCDSCH 588
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sapiens]
Length = 600
Score = 72.0 bits (175), Expect = 3e-12
Identities = 41/137 (29%), Positives = 69/137 (50%), Gaps = 20/137 (14%)
Query: 1034 QEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCL 1093
Q+VE L++++RELQ D + + + E ++ G S+ L
Sbjct: 472 QQVEGLKKELRELQ-----------------DEKAELQKICEEQEQALQEMGLHLSQSKL 514
Query: 1094 SEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLP 1153
+ V++ + W+ D A+HC C+ EF +++R+HHCRNCG++FC C +L
Sbjct: 515 KMEDIKEVNQA-LKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELA 573
Query: 1154 IPDQQLYDPVLVCNSCY 1170
+P PV VC+SC+
Sbjct: 574 LPSYP--KPVRVCDSCH 588
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sapiens]
Length = 708
Score = 72.0 bits (175), Expect = 3e-12
Identities = 41/137 (29%), Positives = 69/137 (50%), Gaps = 20/137 (14%)
Query: 1034 QEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCL 1093
Q+VE L++++RELQ D + + + E ++ G S+ L
Sbjct: 580 QQVEGLKKELRELQ-----------------DEKAELQKICEEQEQALQEMGLHLSQSKL 622
Query: 1094 SEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLP 1153
+ V++ + W+ D A+HC C+ EF +++R+HHCRNCG++FC C +L
Sbjct: 623 KMEDIKEVNQA-LKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELA 681
Query: 1154 IPDQQLYDPVLVCNSCY 1170
+P PV VC+SC+
Sbjct: 682 LPSYP--KPVRVCDSCH 696
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 68.6 bits (166), Expect = 3e-11
Identities = 35/83 (42%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 1111 WVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLY---DPVLVCN 1167
WVPD A +C C+ F KRRHHCR CG VFCA CC LK + LY VC
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKL----LYMDRKEARVCV 751
Query: 1168 SCYEHIQVSRARE-LMSQQLKKP 1189
C+ + ++A E +MS + P
Sbjct: 752 ICHSVLMNAQAWENMMSASSQSP 774
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 68.2 bits (165), Expect = 5e-11
Identities = 35/105 (33%), Positives = 46/105 (43%), Gaps = 8/105 (7%)
Query: 1074 KESDGSDTEDFGSDHSEDCL--------SEASWEPVDKKETEVTRWVPDHMASHCYNCDC 1125
KE T+ S EDC SE + + D + WVPD C C
Sbjct: 769 KEKLRKVTQTLRSAALEDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKA 828
Query: 1126 EFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCY 1170
F + +R+HHCR+CG +FC+ C P+P PV VC CY
Sbjct: 829 PFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 68.2 bits (165), Expect = 5e-11
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 1107 EVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVC 1166
E +WVPD C CD +F R+HHCR CG FC CC K+P+ DPV C
Sbjct: 37 EEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQC 96
Query: 1167 NSCYEHIQVSRARELMSQQLKKPIATAS 1194
C + + E +QLK ++ A+
Sbjct: 97 AEC--ALVSLKEAEFYDKQLKVLLSGAT 122
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,246,954
Number of Sequences: 37866
Number of extensions: 2816730
Number of successful extensions: 9482
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 9201
Number of HSP's gapped (non-prelim): 324
length of query: 1195
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1081
effective length of database: 13,930,794
effective search space: 15059188314
effective search space used: 15059188314
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.