Guide to the Human Genome
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Name: CISH Sequence: fasta or formatted (258aa) NCBI GI: 21614507
Description:

cytokine-inducible SH2-containing protein isoform 2

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [275aa] cytokine-inducible SH2-containing protein isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.9         23           1
 C cysteine            2.3          6           1
 D aspartate           5.4         14           1
 E glutamate           5.4         14           2
 F phenylalanine       3.1          8           1
 G glycine             3.1          8           1
 H histidine           1.9          5           1
 I isoleucine          1.9          5           1
 K lysine              2.7          7           1
 L leucine            12.4         32           2
 M methionine          1.9          5           1
 N asparagine          1.2          3           1
 P proline            12.4         32           3
 Q glutamine           4.3         11           1
 R arginine            7.8         20           2
 S serine              8.1         21           2
 T threonine           5.8         15           2
 V valine              7.4         19           2
 W tryptophan          1.2          3           1
 Y tyrosine            2.7          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cytokine-inducible SH2-containing protein isoform 2 ... 
CISH                  0.972   cytokine-inducible SH2-containing protein isoform 1...
SOCS2                 0.267   suppressor of cytokine signaling-2 
SOCS3                 0.159   suppressor of cytokine signaling 3 
SOCS6                 0.118   suppressor of cytokine signaling 6 
SOCS1                 0.104   suppressor of cytokine signaling 1 
SOCS7                 0.102   suppressor of cytokine signaling 7 
SOCS4                 0.098   suppressor of cytokine signaling 4 
SOCS4                 0.098   suppressor of cytokine signaling 4 
SOCS5                 0.086   suppressor of cytokine signaling 5 
SOCS5                 0.086   suppressor of cytokine signaling 5 
PIK3R2                0.060   phosphoinositide-3-kinase, regulatory subunit 2 (beta...
PIK3R3                0.058   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R3                0.058   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R1                0.048   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R1                0.048   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R1                0.048   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
DAPP1                 0.034   dual adaptor of phosphotyrosine and 3-phosphoinosit...
CSK                   0.032   c-src tyrosine kinase 
CSK                   0.032   c-src tyrosine kinase 
MATK                  0.032   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.032   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.032   megakaryocyte-associated tyrosine kinase isoform a [...
SHF                   0.032   Src homology 2 domain containing F 
FER                   0.030   fer (fps/fes related) tyrosine kinase 
SHE                   0.030   Src homology 2 domain containing E 
CRK                   0.030   v-crk sarcoma virus CT10 oncogene homolog isoform a ...
CRK                   0.030   v-crk sarcoma virus CT10 oncogene homolog isoform b ...
NCK2                  0.028   NCK adaptor protein 2 isoform A 
NCK2                  0.028   NCK adaptor protein 2 isoform A 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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