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Search of human proteins with 21536423
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21536423 amphiphysin isoform 2 [Homo sapiens]
(653 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 1306 0.0
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 1286 0.0
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens] 461 e-129
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 446 e-125
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] 434 e-122
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] 424 e-118
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens] 377 e-104
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens] 369 e-102
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens] 367 e-101
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens] 367 e-101
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens] 357 1e-98
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens] 353 3e-97
gi|49472835 bridging integrator 2 [Homo sapiens] 296 3e-80
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 69 1e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 69 1e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 69 1e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 69 1e-11
gi|39930351 dynamin binding protein [Homo sapiens] 55 2e-07
gi|116284392 mucin 2 precursor [Homo sapiens] 54 6e-07
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 54 6e-07
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 52 1e-06
gi|8923904 bridging integrator 3 [Homo sapiens] 51 3e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 51 4e-06
gi|110349719 titin isoform N2-A [Homo sapiens] 51 4e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 50 5e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 50 5e-06
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 49 1e-05
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 49 1e-05
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 49 2e-05
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 49 2e-05
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 1306 bits (3380), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 1 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL 60
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
Sbjct: 1 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL 60
Query: 61 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT 120
RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
Sbjct: 61 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT 120
Query: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
Sbjct: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
Query: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD 240
EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
Sbjct: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD 240
Query: 241 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
Sbjct: 241 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
Query: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
Sbjct: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
Query: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
Sbjct: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
Query: 421 ICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAES 480
ICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAES
Sbjct: 421 ICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAES 480
Query: 481 AQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETP 540
AQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETP
Sbjct: 481 AQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETP 540
Query: 541 ELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELT 600
ELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELT
Sbjct: 541 ELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELT 600
Query: 601 LQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD 653
LQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
Sbjct: 601 LQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD 653
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 1286 bits (3327), Expect = 0.0
Identities = 653/695 (93%), Positives = 653/695 (93%), Gaps = 42/695 (6%)
Query: 1 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL 60
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
Sbjct: 1 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL 60
Query: 61 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT 120
RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
Sbjct: 61 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT 120
Query: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
Sbjct: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
Query: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD 240
EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
Sbjct: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD 240
Query: 241 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
Sbjct: 241 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
Query: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
Sbjct: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
Query: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
Sbjct: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
Query: 421 ICNL------------------------------------------IIPGADADAAVGTL 438
ICNL IIPGADADAAVGTL
Sbjct: 421 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL 480
Query: 439 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI 498
VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
Sbjct: 481 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI 540
Query: 499 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 558
PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
Sbjct: 541 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 600
Query: 559 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ 618
PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
Sbjct: 601 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ 660
Query: 619 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD 653
DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
Sbjct: 661 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD 695
>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
Length = 593
Score = 461 bits (1185), Expect = e-129
Identities = 272/595 (45%), Positives = 350/595 (58%), Gaps = 60/595 (10%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
Query: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212
AEEE KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
Query: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272
E FHKE++ L L +V+ L QH FT++ PSD+ P + K+PSPP + SP +
Sbjct: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
Query: 273 PTASPNHTLAP---ASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFV 329
P NH P A+P P+SPSQ RKGPPVPP PK TP+KE++QE I+S FED FV
Sbjct: 308 PEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFV 367
Query: 330 PEISVTTPSQNEVP-EVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTS 388
PEISVTTPSQ E P ++ +LLDLDFDP P +P + +P Q++PWDLW
Sbjct: 368 PEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLW--- 420
Query: 389 TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGE 448
+ + +G +G + + Q+ P ++ A GT +A PGE
Sbjct: 421 -EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGE 479
Query: 449 EA--EAEKATVPAGEGVSLEEAKIGT-ETTEGA------------ESAQPEAEELEATVP 493
A EA +++PA + GT E GA AQ + +
Sbjct: 480 TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDEL 539
Query: 494 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 548
Q K V++ P N EE+ E + +G + + + PE TE+ P
Sbjct: 540 QLKAGDVVLVIPFQNPEEQDEGWL-MGVKESDWNQHKELEKCRGVFPENFTERVP 593
Score = 114 bits (284), Expect = 4e-25
Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 20/203 (9%)
Query: 454 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 513
KA P+G+ + + E TE + P E A PS EP E
Sbjct: 406 KAPTPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 461
Query: 514 ENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLAS 569
+E+ G +P +E E AA +S P + E P G D
Sbjct: 462 -SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD---- 516
Query: 570 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 629
LPPGF++KV+ HD+ A ++DEL L+ GDVVLV+P + +QD GWL+GVKES
Sbjct: 517 -------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 569
Query: 630 DWLQYRDLATYKGLFPENFTRRL 652
DW Q+++L +G+FPENFT R+
Sbjct: 570 DWNQHKELEKCRGVFPENFTERV 592
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 446 bits (1146), Expect = e-125
Identities = 258/551 (46%), Positives = 328/551 (59%), Gaps = 47/551 (8%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ RKG
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG 307
Query: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
PPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 308 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ--------------------- 346
Query: 361 PEVTPAGSAGVTHSPMSQ---TLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTD 417
P +PAGS ++ + W T QPA G TQP + +T
Sbjct: 347 PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETA 406
Query: 418 QSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEG 477
S + +P + T+ EG G A + +P G ++ T T
Sbjct: 407 ASEAASSSLPAVVVETFPATVNGTVEGGSG----AGRLDLPPGFMFKVQAQHDYTAT--- 459
Query: 478 AESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTS 537
+ +EL Q K V++ P N EE+ E + +G + + +
Sbjct: 460 ------DTDEL-----QLKAGDVVLVIPFQNPEEQDEGWL-MGVKESDWNQHKELEKCRG 507
Query: 538 ETPELATEQKP 548
PE TE+ P
Sbjct: 508 VFPENFTERVP 518
Score = 110 bits (276), Expect = 3e-24
Identities = 69/184 (37%), Positives = 95/184 (51%), Gaps = 17/184 (9%)
Query: 472 TETTEGA-ESAQPEAEELEATV--PQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTE 528
TE+ G+ S +P A E V P + P +PA E G + GA+ E E
Sbjct: 348 TESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPA-QPAEASEVAGGTQPAAGAQ--EPGE 404
Query: 529 DAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETL 588
AA +S P + E P G D LPPGF++KV+
Sbjct: 405 TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQ 453
Query: 589 HDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENF 648
HD+ A ++DEL L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENF
Sbjct: 454 HDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENF 513
Query: 649 TRRL 652
T R+
Sbjct: 514 TERV 517
>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
Length = 482
Score = 434 bits (1117), Expect = e-122
Identities = 216/339 (63%), Positives = 261/339 (76%), Gaps = 4/339 (1%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ RKG
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG 307
Query: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ 339
PPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 308 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ 346
Score = 111 bits (277), Expect = 2e-24
Identities = 76/241 (31%), Positives = 110/241 (45%), Gaps = 28/241 (11%)
Query: 427 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 483
P +A A S +G+P E P G + A K ++ +G P
Sbjct: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 313
Query: 484 EAEELEATVPQEKV--------IPSVVI----EPASNHEEEGENEITIGAEPKETTEDAA 531
V QE++ +P + + +PA E G + GA+ E E AA
Sbjct: 314 PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ--EPGETAA 371
Query: 532 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 591
+S P + E P G D LPPGF++KV+ HD+
Sbjct: 372 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 420
Query: 592 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 651
A ++DEL L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R
Sbjct: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480
Query: 652 L 652
+
Sbjct: 481 V 481
>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
Length = 497
Score = 424 bits (1091), Expect = e-118
Identities = 216/354 (61%), Positives = 261/354 (73%), Gaps = 19/354 (5%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285
T++ P SD+ P + K+PSPP + SP +P NH P A+
Sbjct: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
Query: 286 PAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ 339
P P+SPSQ RKGPPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 308 PGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ 361
Score = 109 bits (273), Expect = 7e-24
Identities = 73/228 (32%), Positives = 106/228 (46%), Gaps = 28/228 (12%)
Query: 440 SAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQPEAEELEATVPQEK 496
S +G+P E P G + A K ++ +G P V QE+
Sbjct: 282 SPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQ 341
Query: 497 V--------IPSVVI----EPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELAT 544
+ +P + + +PA E G + GA+ E E AA +S P +
Sbjct: 342 ILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ--EPGETAASEAASSSLPAVVV 399
Query: 545 EQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRG 604
E P G D LPPGF++KV+ HD+ A ++DEL L+ G
Sbjct: 400 ETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQLKAG 448
Query: 605 DVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652
DVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 449 DVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 496
>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
Length = 550
Score = 377 bits (968), Expect = e-104
Identities = 242/592 (40%), Positives = 316/592 (53%), Gaps = 97/592 (16%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
Query: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212
AEEE KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
Query: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272
E FHKE++ L L +V+ L QH FT++ PSD+ P + K+PSPP + SP +
Sbjct: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
Query: 273 PTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEI 332
P NH P PA +P T LPK
Sbjct: 308 PEIRVNH-----EPEPAGGATPGAT--------LPK------------------------ 330
Query: 333 SVTTPSQNEVP-EVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDL 391
+PSQ E P ++ +LLDLDFDP P +P + +P Q++PWDLW +
Sbjct: 331 ---SPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLW----EP 379
Query: 392 VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEA- 450
+ +G +G + + Q+ P ++ A GT +A PGE A
Sbjct: 380 TESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAA 439
Query: 451 -EAEKATVPAGEGVSLEEAKIGT-ETTEGA------------ESAQPEAEELEATVPQEK 496
EA +++PA + GT E GA AQ + + Q K
Sbjct: 440 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLK 499
Query: 497 VIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 548
V++ P N EE+ E + +G + + + PE TE+ P
Sbjct: 500 AGDVVLVIPFQNPEEQDEGWL-MGVKESDWNQHKELEKCRGVFPENFTERVP 550
Score = 114 bits (284), Expect = 4e-25
Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 20/203 (9%)
Query: 454 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 513
KA P+G+ + + E TE + P E A PS EP E
Sbjct: 363 KAPTPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 418
Query: 514 ENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLAS 569
+E+ G +P +E E AA +S P + E P G D
Sbjct: 419 -SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD---- 473
Query: 570 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 629
LPPGF++KV+ HD+ A ++DEL L+ GDVVLV+P + +QD GWL+GVKES
Sbjct: 474 -------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 526
Query: 630 DWLQYRDLATYKGLFPENFTRRL 652
DW Q+++L +G+FPENFT R+
Sbjct: 527 DWNQHKELEKCRGVFPENFTERV 549
>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
Length = 475
Score = 369 bits (948), Expect = e-102
Identities = 184/301 (61%), Positives = 226/301 (75%), Gaps = 4/301 (1%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ +
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTES 307
Query: 301 P 301
P
Sbjct: 308 P 308
Score = 114 bits (285), Expect = 3e-25
Identities = 77/233 (33%), Positives = 107/233 (45%), Gaps = 19/233 (8%)
Query: 427 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 483
P +A A S +G+P E P G + A K ++ TE + P
Sbjct: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLP 313
Query: 484 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAAPPGPTSET 539
E A PS EP E +E+ G +P +E E AA +S
Sbjct: 314 SGEPSAAEGTFAVSWPSQTAEPGPAQPAEA-SEVAGGTQPAAGAQEPGETAASEAASSSL 372
Query: 540 PELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDEL 599
P + E P G D LPPGF++KV+ HD+ A ++DEL
Sbjct: 373 PAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDEL 421
Query: 600 TLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652
L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 422 QLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 474
>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
Length = 409
Score = 367 bits (943), Expect = e-101
Identities = 183/297 (61%), Positives = 225/297 (75%), Gaps = 4/297 (1%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQT 297
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ+
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQS 304
Score = 110 bits (276), Expect = 3e-24
Identities = 59/168 (35%), Positives = 87/168 (51%), Gaps = 25/168 (14%)
Query: 510 EEEGENEITIGAEPKETT------EDAAPPGPTSETPELATEQKPIQDPQPTPSA----- 558
++ G N T+ A+P + + P G + TPE+ +P TP A
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
Query: 559 --------------PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRG 604
PA + +LPPGF++KV+ HD+ A ++DEL L+ G
Sbjct: 301 PSQSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAG 360
Query: 605 DVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652
DVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 361 DVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 408
>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
Length = 439
Score = 367 bits (943), Expect = e-101
Identities = 184/303 (60%), Positives = 226/303 (74%), Gaps = 4/303 (1%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ +
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEA 307
Query: 301 PPV 303
V
Sbjct: 308 SEV 310
Score = 114 bits (284), Expect = 4e-25
Identities = 75/231 (32%), Positives = 109/231 (47%), Gaps = 26/231 (11%)
Query: 423 NLIIPGADADAAVGTLVSAAEGAPGEEAEAEKA-TVPAGEGVSLEEAKIGTETTEGAESA 481
N ++ G + T A+ + A+ K+ + P G + E ++ E E A A
Sbjct: 233 NDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP-EPAGGA 291
Query: 482 QPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPE 541
P A +P +PA E G + GA+ E E AA +S P
Sbjct: 292 TPGA-----------TLPKSPSQPAEASEVAGGTQPAAGAQ--EPGETAASEAASSSLPA 338
Query: 542 LATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTL 601
+ E P G D LPPGF++KV+ HD+ A ++DEL L
Sbjct: 339 VVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQL 387
Query: 602 QRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652
+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 388 KAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 438
>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
Length = 454
Score = 357 bits (917), Expect = 1e-98
Identities = 184/318 (57%), Positives = 226/318 (71%), Gaps = 19/318 (5%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285
T++ P SD+ P + K+PSPP + SP +P NH P A+
Sbjct: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
Query: 286 PAPARPRSPSQTRKGPPV 303
P P+SPSQ + V
Sbjct: 308 PGATLPKSPSQPAEASEV 325
Score = 112 bits (279), Expect = 1e-24
Identities = 64/181 (35%), Positives = 92/181 (50%), Gaps = 16/181 (8%)
Query: 476 EGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAA 531
+G+ +A PE P P + P S + +E+ G +P +E E AA
Sbjct: 285 DGSPAATPEIRVNHEPEPAGGATPGATL-PKSPSQPAEASEVAGGTQPAAGAQEPGETAA 343
Query: 532 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 591
+S P + E P G D LPPGF++KV+ HD+
Sbjct: 344 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 392
Query: 592 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 651
A ++DEL L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R
Sbjct: 393 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 452
Query: 652 L 652
+
Sbjct: 453 V 453
>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
Length = 506
Score = 353 bits (906), Expect = 3e-97
Identities = 184/332 (55%), Positives = 226/332 (68%), Gaps = 35/332 (10%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
Query: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212
AEEE KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
Query: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272
E FHKE++ L L +V+ L QH FT++ PSD+ P + K+PSPP + SP +
Sbjct: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
Query: 273 PTASPNHTLAP---ASPAPARPRSPSQTRKGP 301
P NH P A+P P+SPSQ + P
Sbjct: 308 PEIRVNHEPEPAGGATPGATLPKSPSQPTESP 339
Score = 114 bits (285), Expect = 3e-25
Identities = 77/233 (33%), Positives = 107/233 (45%), Gaps = 19/233 (8%)
Query: 427 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 483
P +A A S +G+P E P G + A K ++ TE + P
Sbjct: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLP 344
Query: 484 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAAPPGPTSET 539
E A PS EP E +E+ G +P +E E AA +S
Sbjct: 345 SGEPSAAEGTFAVSWPSQTAEPGPAQPAEA-SEVAGGTQPAAGAQEPGETAASEAASSSL 403
Query: 540 PELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDEL 599
P + E P G D LPPGF++KV+ HD+ A ++DEL
Sbjct: 404 PAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDEL 452
Query: 600 TLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652
L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 453 QLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 505
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 296 bits (759), Expect = 3e-80
Identities = 197/567 (34%), Positives = 294/567 (51%), Gaps = 43/567 (7%)
Query: 7 GIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAA 66
G+FAK VQK+ +RAQEKVLQKLGKA ETKDE+FE+ NF +Q+AEG +L ++L+ +L+A
Sbjct: 11 GLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSA 70
Query: 67 IKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLG 126
+K M E+S +++E+L E+Y +W G E++K + D+LWED+ +KL D ++ T++ Y+
Sbjct: 71 VKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVA 130
Query: 127 QFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVD 186
QF +IK RIAKR RKLVDYDSARHHLEA+Q++K+KDE++ +KAEEEF KAQ VFE+ N +
Sbjct: 131 QFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQE 190
Query: 187 LQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQ 246
L EELP L++ R+G YV F+N+S+L F++E++ L H LYEVM+KL QH++K F ++
Sbjct: 191 LLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVK 250
Query: 247 GAPSDSGPLRIAKTPSPPEE----PSPLPSPTASPNHTLAPASPA-PARPRSPSQTRKGP 301
G S S R + SPP SPL SPT+ +L S + A +G
Sbjct: 251 GLSSSS---RRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGE 307
Query: 302 PVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKP 361
+ ++ +E+++E + + P + P+Q + P E + P
Sbjct: 308 DNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQ-PSPTTERAKSQEEVLPSST 366
Query: 362 EVTPAGSAGVTHSPMSQTLPWDL--WTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419
+P G+ + P S L T S QP S + P T
Sbjct: 367 TPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASP 426
Query: 420 MICNLIIPGADADAAVGTLVS------AAEGAPGEEAEAEKATVPAGEGVSLEEAKIG-- 471
+ IP + + G+ S +P E P + V EAK
Sbjct: 427 RPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENEN 486
Query: 472 -------------TETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEIT 518
T T S EA+++E K+I S + EG++++
Sbjct: 487 IHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLI--------SANSSEGQDQLQ 538
Query: 519 IGAEPKETTEDAAPPG---PTSETPEL 542
+ P+ A P TSE P+L
Sbjct: 539 VSMVPENNNLTAPEPQEEVSTSENPQL 565
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 69.3 bits (168), Expect = 1e-11
Identities = 87/332 (26%), Positives = 125/332 (37%), Gaps = 38/332 (11%)
Query: 261 PSPPEEPSPL----PSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
P+ P+EP+P P+PT + + P PAP P+ P+ T P P PK PT
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTP 330
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
+E + E + TTP + KK + P P+ PA + SP
Sbjct: 331 KEPAPT------TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPT 383
Query: 377 SQTLPWDLWTTS--TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAA 434
+ P T S T +PA + + T P++ S T + P + A
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--------APTTPKEPA 435
Query: 435 VGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGA-----ESAQPEAEELE 489
T A P E A T P + + T E A E+A ++L
Sbjct: 436 PTTPKKPAPTTPKEPA----PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491
Query: 490 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETT-EDAAPPGPTSETPELATEQKP 548
T P EK+ P+ +PA E E T EP TT E+ AP P + P E P
Sbjct: 492 PTTP-EKLAPTTPEKPAPTTPE--ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 548
Query: 549 IQDPQPTPSAPAMGAADQLASAREASQELPPG 580
+P P+ P A + +E + P G
Sbjct: 549 TTPKEPAPTTPKEPAP---TTPKETAPTTPKG 577
Score = 62.4 bits (150), Expect = 1e-09
Identities = 83/337 (24%), Positives = 115/337 (34%), Gaps = 36/337 (10%)
Query: 244 TIQGAPS---DSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
T + AP+ + P P+ P+EPSP + +P P PAP P+ P+ T
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT---TPKEPAPTTPKKPAPTTPK 448
Query: 301 PPVPPLPK---VTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFD 357
P P PK T TK+ E + TTP + KK
Sbjct: 449 EPAPTTPKEPAPTTTKKPAPTT---------PKEPAPTTPKETAPTTPKKLTPTTPEKLA 499
Query: 358 PFKPE----VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
P PE TP A T + T P + T+ P + T P++ + T
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKEPAPTT 558
Query: 414 MQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE 473
+ P A TL A P + A E A E S K
Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618
Query: 474 TTEGAESAQPEAEELEATVPQEK-------VIPSVVIEPA-SNHEEEGENEI--TIGAEP 523
T +G P +E T P+E P+ + EPA + ++ E+ T P
Sbjct: 619 TPKGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676
Query: 524 KETTED-AAPPGPTSETPELATEQKPIQDPQPTPSAP 559
TT D AP P P E P +P P+ P
Sbjct: 677 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 713
Score = 60.8 bits (146), Expect = 4e-09
Identities = 82/323 (25%), Positives = 112/323 (34%), Gaps = 63/323 (19%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVT-PTKELQQE 318
TP+ PEEP+P A+PN P PAP P+ P+ T P P PK T PT
Sbjct: 523 TPTTPEEPAPTTPKAAAPN---TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579
Query: 319 NIISFFEDNFVPEISVTTPSQNE----VPEVKKEETLLDLDFDPFKPE-VTPAGSAGVTH 373
+ E + TTP + P KE T D KP TP G+A T
Sbjct: 580 -------PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD----KPAPTTPKGTAPTTP 628
Query: 374 SPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADA 433
+ T P +PA T P+ T+ T++ P A
Sbjct: 629 KEPAPTTP----------KEPAP-------TTPKGTAPTTLKEPAPTTPKKPAPKELAPT 671
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVP 493
S P E A E K T E + P E+
Sbjct: 672 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVST--- 725
Query: 494 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP--PG-PTSETP---------- 540
P+ EP + H+ E+ + AEP + +P PG PT++TP
Sbjct: 726 -----PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780
Query: 541 --ELATEQKPIQDPQPTPSAPAM 561
+ TE+ P+ T +AP M
Sbjct: 781 AKDKTTERDLRTTPETTTAAPKM 803
Score = 55.8 bits (133), Expect = 1e-07
Identities = 82/348 (23%), Positives = 115/348 (33%), Gaps = 32/348 (9%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPL----PSPTASPNHT-LAPASPAPARPRSPSQTRKGPPV 303
P + P P+ P+EP+P P+PT P PAP + PS T P
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
P K PT + + E S TT ++ P KE
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-TKEPAPTTPKEPA-----------PT 437
Query: 364 TPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICN 423
TP A T + T P + T+T P + T P++T+ T +
Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAPTTPKETAPTTPKKLTPTTPE 496
Query: 424 LIIPGADADAAVGTLVSAAEGAPGEEA----EAEKATVPAGEGVSLEEAKIGTETTEGA- 478
+ P A T A P E E T P + + T E A
Sbjct: 497 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556
Query: 479 ----ESAQPEAEELEATVPQEKVIPSVVIEPA-SNHEEEGENEI--TIGAEPKETTED-A 530
E A +E T P + P+ + EPA + ++ E+ T EP TT D
Sbjct: 557 TTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615
Query: 531 APPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELP 578
AP P P E P +P P+ P A L + + P
Sbjct: 616 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 663
Score = 55.5 bits (132), Expect = 2e-07
Identities = 80/346 (23%), Positives = 120/346 (34%), Gaps = 32/346 (9%)
Query: 240 DKAFTIQGAPSDSGPLRIAKT------PSPPEEPSPL----PSPTA--SPNHTLAPASPA 287
+ A T P+ + P + A T P+ P+EP+P PSPT P T ++P
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398
Query: 288 PARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ +P+ T+ P P P T TKE P+ T + P K
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPK 456
Query: 348 E----ETLLDLDFDPFKP-EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG 402
E T P +P TP +A T ++ T P L T+ + P +
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL-A 515
Query: 403 FTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEG 462
T P++ + T + P + A T A P E A T P
Sbjct: 516 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA----PTTPK--- 568
Query: 463 VSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAE 522
E A + T +P + P+E + P+ EP S ++ G
Sbjct: 569 ---ETAPTTPKGTAPTTLKEPAPTTPKKPAPKE-LAPTTTKEPTSTTCDKPAPTTPKGTA 624
Query: 523 PKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLA 568
P T ++ AP P P P +P P+ P A +LA
Sbjct: 625 P-TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 669
Score = 46.6 bits (109), Expect = 7e-05
Identities = 67/332 (20%), Positives = 115/332 (34%), Gaps = 49/332 (14%)
Query: 261 PSPPEEPSPLPSPTASPNHTLAPASPAPARP----------RSPSQTRKGPPVPPLPKVT 310
P+ P+EP+P +P PA P +P + P+ T P P PK T
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692
Query: 311 -PTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSA 369
PT + PE T S+ P KE T + D PE++ +
Sbjct: 693 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 752
Query: 370 -GVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPG 428
+ +SP +P TT T PA+ T+P+ T+ +T +
Sbjct: 753 KALENSPKEPGVP----TTKT----PAA-------TKPEMTTTAKDKTTER--------- 788
Query: 429 ADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE-------TTEGAESA 481
D T +A + EK T + + T+ TT +
Sbjct: 789 -DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 847
Query: 482 QPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPE 541
P+ + T+ +++ E + ++ N +P++ T+ P T +
Sbjct: 848 APKVTTTKKTITTTEIMNKP--EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 905
Query: 542 LATEQKPIQDPQP---TPSAPAMGAADQLASA 570
+ +KP P P T + P + ++A A
Sbjct: 906 MPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 937
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/303 (21%), Positives = 91/303 (30%), Gaps = 50/303 (16%)
Query: 257 IAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
+A T +P+P T P P P P+ P+ T P P K P
Sbjct: 187 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP----- 241
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
TTP + K T TP A T
Sbjct: 242 ------------------TTPKEPAPTTTKSAPT-------------TPKEPAPTTTKEP 270
Query: 377 SQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVG 436
+ T P + T+T +PA + + T P++ + T + P + A
Sbjct: 271 APTTPKEPAPTTTK--EPAPTTTKSAPTTPKEPAPTTPKKP--------APTTPKEPAPT 320
Query: 437 TLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEK 496
T P E A K P A T E A +E T +E
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 380
Query: 497 VIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTP 556
P+ EPA + T EP TT +AP P +P E P +P P
Sbjct: 381 -SPTTPKEPAPTTTKSAP---TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 436
Query: 557 SAP 559
+ P
Sbjct: 437 TTP 439
Score = 43.1 bits (100), Expect = 8e-04
Identities = 72/307 (23%), Positives = 119/307 (38%), Gaps = 31/307 (10%)
Query: 259 KTPSPPE-EPSPLPSPTASPNHTLAPASP---APARPRSPSQTRKGPPVPPLPKVTPTKE 314
K P+P E P+ PT++ + AP +P AP P+ P+ T P P P+ P
Sbjct: 661 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT 720
Query: 315 LQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHS 374
+ + E P +P ++ PE+ E T L+ P +P V + T
Sbjct: 721 SEVSTPTTTKE----PTTIHKSPDES-TPELSAEPTPKALENSPKEPGVPTTKTPAATKP 775
Query: 375 PMSQTLPWDLWTTSTDL-VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADA 433
M+ T TT DL P + + T ++T+ T +T +S I A
Sbjct: 776 EMTTTAKDK--TTERDLRTTPETTTAAPKMT--KETATTTEKTTESKI--------TATT 823
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE-TTEGAESAQPE--AEELEA 490
T + + P + K T A + + ++ TE + E+A+P+ A +A
Sbjct: 824 TQVTSTTTQDTTP-FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 882
Query: 491 TVPQEKVIPSVVIEPASNHEEEGENEI---TIGAEPKETTEDAAPPGPTSETPE--LATE 545
T P+ + +P S + + + P++ T PTS E L T
Sbjct: 883 TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 942
Query: 546 QKPIQDP 552
+P Q P
Sbjct: 943 TRPNQTP 949
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 69.3 bits (168), Expect = 1e-11
Identities = 87/332 (26%), Positives = 125/332 (37%), Gaps = 38/332 (11%)
Query: 261 PSPPEEPSPL----PSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
P+ P+EP+P P+PT + + P PAP P+ P+ T P P PK PT
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTP 371
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
+E + E + TTP + KK + P P+ PA + SP
Sbjct: 372 KEPAPT------TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPT 424
Query: 377 SQTLPWDLWTTS--TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAA 434
+ P T S T +PA + + T P++ S T + P + A
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--------APTTPKEPA 476
Query: 435 VGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGA-----ESAQPEAEELE 489
T A P E A T P + + T E A E+A ++L
Sbjct: 477 PTTPKKPAPTTPKEPA----PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532
Query: 490 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETT-EDAAPPGPTSETPELATEQKP 548
T P EK+ P+ +PA E E T EP TT E+ AP P + P E P
Sbjct: 533 PTTP-EKLAPTTPEKPAPTTPE--ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 589
Query: 549 IQDPQPTPSAPAMGAADQLASAREASQELPPG 580
+P P+ P A + +E + P G
Sbjct: 590 TTPKEPAPTTPKEPAP---TTPKETAPTTPKG 618
Score = 62.4 bits (150), Expect = 1e-09
Identities = 83/337 (24%), Positives = 115/337 (34%), Gaps = 36/337 (10%)
Query: 244 TIQGAPS---DSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
T + AP+ + P P+ P+EPSP + +P P PAP P+ P+ T
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT---TPKEPAPTTPKKPAPTTPK 489
Query: 301 PPVPPLPK---VTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFD 357
P P PK T TK+ E + TTP + KK
Sbjct: 490 EPAPTTPKEPAPTTTKKPAPTT---------PKEPAPTTPKETAPTTPKKLTPTTPEKLA 540
Query: 358 PFKPE----VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
P PE TP A T + T P + T+ P + T P++ + T
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKEPAPTT 599
Query: 414 MQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE 473
+ P A TL A P + A E A E S K
Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659
Query: 474 TTEGAESAQPEAEELEATVPQEK-------VIPSVVIEPA-SNHEEEGENEI--TIGAEP 523
T +G P +E T P+E P+ + EPA + ++ E+ T P
Sbjct: 660 TPKGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717
Query: 524 KETTED-AAPPGPTSETPELATEQKPIQDPQPTPSAP 559
TT D AP P P E P +P P+ P
Sbjct: 718 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 754
Score = 60.8 bits (146), Expect = 4e-09
Identities = 82/323 (25%), Positives = 112/323 (34%), Gaps = 63/323 (19%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVT-PTKELQQE 318
TP+ PEEP+P A+PN P PAP P+ P+ T P P PK T PT
Sbjct: 564 TPTTPEEPAPTTPKAAAPN---TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620
Query: 319 NIISFFEDNFVPEISVTTPSQNE----VPEVKKEETLLDLDFDPFKPE-VTPAGSAGVTH 373
+ E + TTP + P KE T D KP TP G+A T
Sbjct: 621 -------PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD----KPAPTTPKGTAPTTP 669
Query: 374 SPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADA 433
+ T P +PA T P+ T+ T++ P A
Sbjct: 670 KEPAPTTP----------KEPAP-------TTPKGTAPTTLKEPAPTTPKKPAPKELAPT 712
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVP 493
S P E A E K T E + P E+
Sbjct: 713 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVST--- 766
Query: 494 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP--PG-PTSETP---------- 540
P+ EP + H+ E+ + AEP + +P PG PT++TP
Sbjct: 767 -----PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821
Query: 541 --ELATEQKPIQDPQPTPSAPAM 561
+ TE+ P+ T +AP M
Sbjct: 822 AKDKTTERDLRTTPETTTAAPKM 844
Score = 55.8 bits (133), Expect = 1e-07
Identities = 82/348 (23%), Positives = 115/348 (33%), Gaps = 32/348 (9%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPL----PSPTASPNHT-LAPASPAPARPRSPSQTRKGPPV 303
P + P P+ P+EP+P P+PT P PAP + PS T P
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
P K PT + + E S TT ++ P KE
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-TKEPAPTTPKEPA-----------PT 478
Query: 364 TPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICN 423
TP A T + T P + T+T P + T P++T+ T +
Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAPTTPKETAPTTPKKLTPTTPE 537
Query: 424 LIIPGADADAAVGTLVSAAEGAPGEEA----EAEKATVPAGEGVSLEEAKIGTETTEGA- 478
+ P A T A P E E T P + + T E A
Sbjct: 538 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597
Query: 479 ----ESAQPEAEELEATVPQEKVIPSVVIEPA-SNHEEEGENEI--TIGAEPKETTED-A 530
E A +E T P + P+ + EPA + ++ E+ T EP TT D
Sbjct: 598 TTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656
Query: 531 APPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELP 578
AP P P E P +P P+ P A L + + P
Sbjct: 657 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 704
Score = 55.5 bits (132), Expect = 2e-07
Identities = 80/346 (23%), Positives = 120/346 (34%), Gaps = 32/346 (9%)
Query: 240 DKAFTIQGAPSDSGPLRIAKT------PSPPEEPSPL----PSPTA--SPNHTLAPASPA 287
+ A T P+ + P + A T P+ P+EP+P PSPT P T ++P
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 439
Query: 288 PARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ +P+ T+ P P P T TKE P+ T + P K
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPK 497
Query: 348 E----ETLLDLDFDPFKP-EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG 402
E T P +P TP +A T ++ T P L T+ + P +
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL-A 556
Query: 403 FTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEG 462
T P++ + T + P + A T A P E A T P
Sbjct: 557 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA----PTTPK--- 609
Query: 463 VSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAE 522
E A + T +P + P+E + P+ EP S ++ G
Sbjct: 610 ---ETAPTTPKGTAPTTLKEPAPTTPKKPAPKE-LAPTTTKEPTSTTCDKPAPTTPKGTA 665
Query: 523 PKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLA 568
P T ++ AP P P P +P P+ P A +LA
Sbjct: 666 P-TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 710
Score = 46.6 bits (109), Expect = 7e-05
Identities = 67/332 (20%), Positives = 115/332 (34%), Gaps = 49/332 (14%)
Query: 261 PSPPEEPSPLPSPTASPNHTLAPASPAPARP----------RSPSQTRKGPPVPPLPKVT 310
P+ P+EP+P +P PA P +P + P+ T P P PK T
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733
Query: 311 -PTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSA 369
PT + PE T S+ P KE T + D PE++ +
Sbjct: 734 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 793
Query: 370 -GVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPG 428
+ +SP +P TT T PA+ T+P+ T+ +T +
Sbjct: 794 KALENSPKEPGVP----TTKT----PAA-------TKPEMTTTAKDKTTER--------- 829
Query: 429 ADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE-------TTEGAESA 481
D T +A + EK T + + T+ TT +
Sbjct: 830 -DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 888
Query: 482 QPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPE 541
P+ + T+ +++ E + ++ N +P++ T+ P T +
Sbjct: 889 APKVTTTKKTITTTEIMNKP--EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 946
Query: 542 LATEQKPIQDPQP---TPSAPAMGAADQLASA 570
+ +KP P P T + P + ++A A
Sbjct: 947 MPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 978
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/303 (21%), Positives = 91/303 (30%), Gaps = 50/303 (16%)
Query: 257 IAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
+A T +P+P T P P P P+ P+ T P P K P
Sbjct: 228 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP----- 282
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
TTP + K T TP A T
Sbjct: 283 ------------------TTPKEPAPTTTKSAPT-------------TPKEPAPTTTKEP 311
Query: 377 SQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVG 436
+ T P + T+T +PA + + T P++ + T + P + A
Sbjct: 312 APTTPKEPAPTTTK--EPAPTTTKSAPTTPKEPAPTTPKKP--------APTTPKEPAPT 361
Query: 437 TLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEK 496
T P E A K P A T E A +E T +E
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 421
Query: 497 VIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTP 556
P+ EPA + T EP TT +AP P +P E P +P P
Sbjct: 422 -SPTTPKEPAPTTTKSAP---TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 477
Query: 557 SAP 559
+ P
Sbjct: 478 TTP 480
Score = 43.1 bits (100), Expect = 8e-04
Identities = 72/307 (23%), Positives = 119/307 (38%), Gaps = 31/307 (10%)
Query: 259 KTPSPPE-EPSPLPSPTASPNHTLAPASP---APARPRSPSQTRKGPPVPPLPKVTPTKE 314
K P+P E P+ PT++ + AP +P AP P+ P+ T P P P+ P
Sbjct: 702 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT 761
Query: 315 LQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHS 374
+ + E P +P ++ PE+ E T L+ P +P V + T
Sbjct: 762 SEVSTPTTTKE----PTTIHKSPDES-TPELSAEPTPKALENSPKEPGVPTTKTPAATKP 816
Query: 375 PMSQTLPWDLWTTSTDL-VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADA 433
M+ T TT DL P + + T ++T+ T +T +S I A
Sbjct: 817 EMTTTAKDK--TTERDLRTTPETTTAAPKMT--KETATTTEKTTESKI--------TATT 864
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE-TTEGAESAQPE--AEELEA 490
T + + P + K T A + + ++ TE + E+A+P+ A +A
Sbjct: 865 TQVTSTTTQDTTP-FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 923
Query: 491 TVPQEKVIPSVVIEPASNHEEEGENEI---TIGAEPKETTEDAAPPGPTSETPE--LATE 545
T P+ + +P S + + + P++ T PTS E L T
Sbjct: 924 TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 983
Query: 546 QKPIQDP 552
+P Q P
Sbjct: 984 TRPNQTP 990
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 69.3 bits (168), Expect = 1e-11
Identities = 87/332 (26%), Positives = 125/332 (37%), Gaps = 38/332 (11%)
Query: 261 PSPPEEPSPL----PSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
P+ P+EP+P P+PT + + P PAP P+ P+ T P P PK PT
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTP 423
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
+E + E + TTP + KK + P P+ PA + SP
Sbjct: 424 KEPAPT------TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPT 476
Query: 377 SQTLPWDLWTTS--TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAA 434
+ P T S T +PA + + T P++ S T + P + A
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--------APTTPKEPA 528
Query: 435 VGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGA-----ESAQPEAEELE 489
T A P E A T P + + T E A E+A ++L
Sbjct: 529 PTTPKKPAPTTPKEPA----PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584
Query: 490 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETT-EDAAPPGPTSETPELATEQKP 548
T P EK+ P+ +PA E E T EP TT E+ AP P + P E P
Sbjct: 585 PTTP-EKLAPTTPEKPAPTTPE--ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 641
Query: 549 IQDPQPTPSAPAMGAADQLASAREASQELPPG 580
+P P+ P A + +E + P G
Sbjct: 642 TTPKEPAPTTPKEPAP---TTPKETAPTTPKG 670
Score = 62.4 bits (150), Expect = 1e-09
Identities = 83/337 (24%), Positives = 115/337 (34%), Gaps = 36/337 (10%)
Query: 244 TIQGAPS---DSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
T + AP+ + P P+ P+EPSP + +P P PAP P+ P+ T
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT---TPKEPAPTTPKKPAPTTPK 541
Query: 301 PPVPPLPK---VTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFD 357
P P PK T TK+ E + TTP + KK
Sbjct: 542 EPAPTTPKEPAPTTTKKPAPTT---------PKEPAPTTPKETAPTTPKKLTPTTPEKLA 592
Query: 358 PFKPE----VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
P PE TP A T + T P + T+ P + T P++ + T
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKEPAPTT 651
Query: 414 MQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE 473
+ P A TL A P + A E A E S K
Sbjct: 652 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 711
Query: 474 TTEGAESAQPEAEELEATVPQEK-------VIPSVVIEPA-SNHEEEGENEI--TIGAEP 523
T +G P +E T P+E P+ + EPA + ++ E+ T P
Sbjct: 712 TPKGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 769
Query: 524 KETTED-AAPPGPTSETPELATEQKPIQDPQPTPSAP 559
TT D AP P P E P +P P+ P
Sbjct: 770 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 806
Score = 60.8 bits (146), Expect = 4e-09
Identities = 82/323 (25%), Positives = 112/323 (34%), Gaps = 63/323 (19%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVT-PTKELQQE 318
TP+ PEEP+P A+PN P PAP P+ P+ T P P PK T PT
Sbjct: 616 TPTTPEEPAPTTPKAAAPN---TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 672
Query: 319 NIISFFEDNFVPEISVTTPSQNE----VPEVKKEETLLDLDFDPFKPE-VTPAGSAGVTH 373
+ E + TTP + P KE T D KP TP G+A T
Sbjct: 673 -------PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD----KPAPTTPKGTAPTTP 721
Query: 374 SPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADA 433
+ T P +PA T P+ T+ T++ P A
Sbjct: 722 KEPAPTTP----------KEPAP-------TTPKGTAPTTLKEPAPTTPKKPAPKELAPT 764
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVP 493
S P E A E K T E + P E+
Sbjct: 765 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVST--- 818
Query: 494 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP--PG-PTSETP---------- 540
P+ EP + H+ E+ + AEP + +P PG PT++TP
Sbjct: 819 -----PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873
Query: 541 --ELATEQKPIQDPQPTPSAPAM 561
+ TE+ P+ T +AP M
Sbjct: 874 AKDKTTERDLRTTPETTTAAPKM 896
Score = 55.8 bits (133), Expect = 1e-07
Identities = 82/348 (23%), Positives = 115/348 (33%), Gaps = 32/348 (9%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPL----PSPTASPNHT-LAPASPAPARPRSPSQTRKGPPV 303
P + P P+ P+EP+P P+PT P PAP + PS T P
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 482
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
P K PT + + E S TT ++ P KE
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-TKEPAPTTPKEPA-----------PT 530
Query: 364 TPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICN 423
TP A T + T P + T+T P + T P++T+ T +
Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAPTTPKETAPTTPKKLTPTTPE 589
Query: 424 LIIPGADADAAVGTLVSAAEGAPGEEA----EAEKATVPAGEGVSLEEAKIGTETTEGA- 478
+ P A T A P E E T P + + T E A
Sbjct: 590 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649
Query: 479 ----ESAQPEAEELEATVPQEKVIPSVVIEPA-SNHEEEGENEI--TIGAEPKETTED-A 530
E A +E T P + P+ + EPA + ++ E+ T EP TT D
Sbjct: 650 TTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708
Query: 531 APPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELP 578
AP P P E P +P P+ P A L + + P
Sbjct: 709 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 756
Score = 55.5 bits (132), Expect = 2e-07
Identities = 80/346 (23%), Positives = 120/346 (34%), Gaps = 32/346 (9%)
Query: 240 DKAFTIQGAPSDSGPLRIAKT------PSPPEEPSPL----PSPTA--SPNHTLAPASPA 287
+ A T P+ + P + A T P+ P+EP+P PSPT P T ++P
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491
Query: 288 PARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ +P+ T+ P P P T TKE P+ T + P K
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPK 549
Query: 348 E----ETLLDLDFDPFKP-EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG 402
E T P +P TP +A T ++ T P L T+ + P +
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL-A 608
Query: 403 FTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEG 462
T P++ + T + P + A T A P E A T P
Sbjct: 609 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA----PTTPK--- 661
Query: 463 VSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAE 522
E A + T +P + P+E + P+ EP S ++ G
Sbjct: 662 ---ETAPTTPKGTAPTTLKEPAPTTPKKPAPKE-LAPTTTKEPTSTTCDKPAPTTPKGTA 717
Query: 523 PKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLA 568
P T ++ AP P P P +P P+ P A +LA
Sbjct: 718 P-TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 762
Score = 46.6 bits (109), Expect = 7e-05
Identities = 67/332 (20%), Positives = 115/332 (34%), Gaps = 49/332 (14%)
Query: 261 PSPPEEPSPLPSPTASPNHTLAPASPAPARP----------RSPSQTRKGPPVPPLPKVT 310
P+ P+EP+P +P PA P +P + P+ T P P PK T
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785
Query: 311 -PTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSA 369
PT + PE T S+ P KE T + D PE++ +
Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 845
Query: 370 -GVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPG 428
+ +SP +P TT T PA+ T+P+ T+ +T +
Sbjct: 846 KALENSPKEPGVP----TTKT----PAA-------TKPEMTTTAKDKTTER--------- 881
Query: 429 ADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE-------TTEGAESA 481
D T +A + EK T + + T+ TT +
Sbjct: 882 -DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 940
Query: 482 QPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPE 541
P+ + T+ +++ E + ++ N +P++ T+ P T +
Sbjct: 941 APKVTTTKKTITTTEIMNKP--EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 998
Query: 542 LATEQKPIQDPQP---TPSAPAMGAADQLASA 570
+ +KP P P T + P + ++A A
Sbjct: 999 MPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1030
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/303 (21%), Positives = 91/303 (30%), Gaps = 50/303 (16%)
Query: 257 IAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
+A T +P+P T P P P P+ P+ T P P K P
Sbjct: 280 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP----- 334
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
TTP + K T TP A T
Sbjct: 335 ------------------TTPKEPAPTTTKSAPT-------------TPKEPAPTTTKEP 363
Query: 377 SQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVG 436
+ T P + T+T +PA + + T P++ + T + P + A
Sbjct: 364 APTTPKEPAPTTTK--EPAPTTTKSAPTTPKEPAPTTPKKP--------APTTPKEPAPT 413
Query: 437 TLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEK 496
T P E A K P A T E A +E T +E
Sbjct: 414 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 473
Query: 497 VIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTP 556
P+ EPA + T EP TT +AP P +P E P +P P
Sbjct: 474 -SPTTPKEPAPTTTKSAP---TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529
Query: 557 SAP 559
+ P
Sbjct: 530 TTP 532
Score = 43.1 bits (100), Expect = 8e-04
Identities = 72/307 (23%), Positives = 119/307 (38%), Gaps = 31/307 (10%)
Query: 259 KTPSPPE-EPSPLPSPTASPNHTLAPASP---APARPRSPSQTRKGPPVPPLPKVTPTKE 314
K P+P E P+ PT++ + AP +P AP P+ P+ T P P P+ P
Sbjct: 754 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT 813
Query: 315 LQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHS 374
+ + E P +P ++ PE+ E T L+ P +P V + T
Sbjct: 814 SEVSTPTTTKE----PTTIHKSPDES-TPELSAEPTPKALENSPKEPGVPTTKTPAATKP 868
Query: 375 PMSQTLPWDLWTTSTDL-VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADA 433
M+ T TT DL P + + T ++T+ T +T +S I A
Sbjct: 869 EMTTTAKDK--TTERDLRTTPETTTAAPKMT--KETATTTEKTTESKI--------TATT 916
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE-TTEGAESAQPE--AEELEA 490
T + + P + K T A + + ++ TE + E+A+P+ A +A
Sbjct: 917 TQVTSTTTQDTTP-FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 975
Query: 491 TVPQEKVIPSVVIEPASNHEEEGENEI---TIGAEPKETTEDAAPPGPTSETPE--LATE 545
T P+ + +P S + + + P++ T PTS E L T
Sbjct: 976 TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 1035
Query: 546 QKPIQDP 552
+P Q P
Sbjct: 1036 TRPNQTP 1042
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 69.3 bits (168), Expect = 1e-11
Identities = 87/332 (26%), Positives = 125/332 (37%), Gaps = 38/332 (11%)
Query: 261 PSPPEEPSPL----PSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
P+ P+EP+P P+PT + + P PAP P+ P+ T P P PK PT
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTP 464
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
+E + E + TTP + KK + P P+ PA + SP
Sbjct: 465 KEPAPT------TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPT 517
Query: 377 SQTLPWDLWTTS--TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAA 434
+ P T S T +PA + + T P++ S T + P + A
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--------APTTPKEPA 569
Query: 435 VGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGA-----ESAQPEAEELE 489
T A P E A T P + + T E A E+A ++L
Sbjct: 570 PTTPKKPAPTTPKEPA----PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625
Query: 490 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETT-EDAAPPGPTSETPELATEQKP 548
T P EK+ P+ +PA E E T EP TT E+ AP P + P E P
Sbjct: 626 PTTP-EKLAPTTPEKPAPTTPE--ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 682
Query: 549 IQDPQPTPSAPAMGAADQLASAREASQELPPG 580
+P P+ P A + +E + P G
Sbjct: 683 TTPKEPAPTTPKEPAP---TTPKETAPTTPKG 711
Score = 62.4 bits (150), Expect = 1e-09
Identities = 83/337 (24%), Positives = 115/337 (34%), Gaps = 36/337 (10%)
Query: 244 TIQGAPS---DSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
T + AP+ + P P+ P+EPSP + +P P PAP P+ P+ T
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT---TPKEPAPTTPKKPAPTTPK 582
Query: 301 PPVPPLPK---VTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFD 357
P P PK T TK+ E + TTP + KK
Sbjct: 583 EPAPTTPKEPAPTTTKKPAPTT---------PKEPAPTTPKETAPTTPKKLTPTTPEKLA 633
Query: 358 PFKPE----VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
P PE TP A T + T P + T+ P + T P++ + T
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKEPAPTT 692
Query: 414 MQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE 473
+ P A TL A P + A E A E S K
Sbjct: 693 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 752
Query: 474 TTEGAESAQPEAEELEATVPQEK-------VIPSVVIEPA-SNHEEEGENEI--TIGAEP 523
T +G P +E T P+E P+ + EPA + ++ E+ T P
Sbjct: 753 TPKGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 810
Query: 524 KETTED-AAPPGPTSETPELATEQKPIQDPQPTPSAP 559
TT D AP P P E P +P P+ P
Sbjct: 811 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 847
Score = 60.8 bits (146), Expect = 4e-09
Identities = 82/323 (25%), Positives = 112/323 (34%), Gaps = 63/323 (19%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVT-PTKELQQE 318
TP+ PEEP+P A+PN P PAP P+ P+ T P P PK T PT
Sbjct: 657 TPTTPEEPAPTTPKAAAPN---TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713
Query: 319 NIISFFEDNFVPEISVTTPSQNE----VPEVKKEETLLDLDFDPFKPE-VTPAGSAGVTH 373
+ E + TTP + P KE T D KP TP G+A T
Sbjct: 714 -------PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD----KPAPTTPKGTAPTTP 762
Query: 374 SPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADA 433
+ T P +PA T P+ T+ T++ P A
Sbjct: 763 KEPAPTTP----------KEPAP-------TTPKGTAPTTLKEPAPTTPKKPAPKELAPT 805
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVP 493
S P E A E K T E + P E+
Sbjct: 806 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE---TPPPTTSEVST--- 859
Query: 494 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP--PG-PTSETP---------- 540
P+ EP + H+ E+ + AEP + +P PG PT++TP
Sbjct: 860 -----PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 914
Query: 541 --ELATEQKPIQDPQPTPSAPAM 561
+ TE+ P+ T +AP M
Sbjct: 915 AKDKTTERDLRTTPETTTAAPKM 937
Score = 55.8 bits (133), Expect = 1e-07
Identities = 82/348 (23%), Positives = 115/348 (33%), Gaps = 32/348 (9%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPL----PSPTASPNHT-LAPASPAPARPRSPSQTRKGPPV 303
P + P P+ P+EP+P P+PT P PAP + PS T P
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 523
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
P K PT + + E S TT ++ P KE
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-TKEPAPTTPKEPA-----------PT 571
Query: 364 TPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICN 423
TP A T + T P + T+T P + T P++T+ T +
Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAPTTPKETAPTTPKKLTPTTPE 630
Query: 424 LIIPGADADAAVGTLVSAAEGAPGEEA----EAEKATVPAGEGVSLEEAKIGTETTEGA- 478
+ P A T A P E E T P + + T E A
Sbjct: 631 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690
Query: 479 ----ESAQPEAEELEATVPQEKVIPSVVIEPA-SNHEEEGENEI--TIGAEPKETTED-A 530
E A +E T P + P+ + EPA + ++ E+ T EP TT D
Sbjct: 691 TTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 749
Query: 531 APPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELP 578
AP P P E P +P P+ P A L + + P
Sbjct: 750 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 797
Score = 55.5 bits (132), Expect = 2e-07
Identities = 80/346 (23%), Positives = 120/346 (34%), Gaps = 32/346 (9%)
Query: 240 DKAFTIQGAPSDSGPLRIAKT------PSPPEEPSPL----PSPTA--SPNHTLAPASPA 287
+ A T P+ + P + A T P+ P+EP+P PSPT P T ++P
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532
Query: 288 PARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ +P+ T+ P P P T TKE P+ T + P K
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPK 590
Query: 348 E----ETLLDLDFDPFKP-EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG 402
E T P +P TP +A T ++ T P L T+ + P +
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL-A 649
Query: 403 FTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEG 462
T P++ + T + P + A T A P E A T P
Sbjct: 650 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA----PTTPK--- 702
Query: 463 VSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAE 522
E A + T +P + P+E + P+ EP S ++ G
Sbjct: 703 ---ETAPTTPKGTAPTTLKEPAPTTPKKPAPKE-LAPTTTKEPTSTTCDKPAPTTPKGTA 758
Query: 523 PKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLA 568
P T ++ AP P P P +P P+ P A +LA
Sbjct: 759 P-TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 803
Score = 46.6 bits (109), Expect = 7e-05
Identities = 67/332 (20%), Positives = 115/332 (34%), Gaps = 49/332 (14%)
Query: 261 PSPPEEPSPLPSPTASPNHTLAPASPAPARP----------RSPSQTRKGPPVPPLPKVT 310
P+ P+EP+P +P PA P +P + P+ T P P PK T
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826
Query: 311 -PTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSA 369
PT + PE T S+ P KE T + D PE++ +
Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 886
Query: 370 -GVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPG 428
+ +SP +P TT T PA+ T+P+ T+ +T +
Sbjct: 887 KALENSPKEPGVP----TTKT----PAA-------TKPEMTTTAKDKTTER--------- 922
Query: 429 ADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE-------TTEGAESA 481
D T +A + EK T + + T+ TT +
Sbjct: 923 -DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 981
Query: 482 QPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPE 541
P+ + T+ +++ E + ++ N +P++ T+ P T +
Sbjct: 982 APKVTTTKKTITTTEIMNKP--EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT 1039
Query: 542 LATEQKPIQDPQP---TPSAPAMGAADQLASA 570
+ +KP P P T + P + ++A A
Sbjct: 1040 MPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1071
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/303 (21%), Positives = 91/303 (30%), Gaps = 50/303 (16%)
Query: 257 IAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
+A T +P+P T P P P P+ P+ T P P K P
Sbjct: 321 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP----- 375
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
TTP + K T TP A T
Sbjct: 376 ------------------TTPKEPAPTTTKSAPT-------------TPKEPAPTTTKEP 404
Query: 377 SQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVG 436
+ T P + T+T +PA + + T P++ + T + P + A
Sbjct: 405 APTTPKEPAPTTTK--EPAPTTTKSAPTTPKEPAPTTPKKP--------APTTPKEPAPT 454
Query: 437 TLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEK 496
T P E A K P A T E A +E T +E
Sbjct: 455 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 514
Query: 497 VIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTP 556
P+ EPA + T EP TT +AP P +P E P +P P
Sbjct: 515 -SPTTPKEPAPTTTKSAP---TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570
Query: 557 SAP 559
+ P
Sbjct: 571 TTP 573
Score = 43.1 bits (100), Expect = 8e-04
Identities = 72/307 (23%), Positives = 119/307 (38%), Gaps = 31/307 (10%)
Query: 259 KTPSPPE-EPSPLPSPTASPNHTLAPASP---APARPRSPSQTRKGPPVPPLPKVTPTKE 314
K P+P E P+ PT++ + AP +P AP P+ P+ T P P P+ P
Sbjct: 795 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT 854
Query: 315 LQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHS 374
+ + E P +P ++ PE+ E T L+ P +P V + T
Sbjct: 855 SEVSTPTTTKE----PTTIHKSPDES-TPELSAEPTPKALENSPKEPGVPTTKTPAATKP 909
Query: 375 PMSQTLPWDLWTTSTDL-VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADA 433
M+ T TT DL P + + T ++T+ T +T +S I A
Sbjct: 910 EMTTTAKDK--TTERDLRTTPETTTAAPKMT--KETATTTEKTTESKI--------TATT 957
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE-TTEGAESAQPE--AEELEA 490
T + + P + K T A + + ++ TE + E+A+P+ A +A
Sbjct: 958 TQVTSTTTQDTTP-FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 1016
Query: 491 TVPQEKVIPSVVIEPASNHEEEGENEI---TIGAEPKETTEDAAPPGPTSETPE--LATE 545
T P+ + +P S + + + P++ T PTS E L T
Sbjct: 1017 TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 1076
Query: 546 QKPIQDP 552
+P Q P
Sbjct: 1077 TRPNQTP 1083
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 55.1 bits (131), Expect = 2e-07
Identities = 51/209 (24%), Positives = 83/209 (39%), Gaps = 15/209 (7%)
Query: 12 NVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQ 71
++ K+ NR + G A + KDE FEE +NF+ QE R+L YL I+ +
Sbjct: 996 SIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIR--E 1053
Query: 72 EASMKLTESLHEVYEPDWYGREDVKMVGEK----CDVLWEDFHQKLVDGSLLTLDTYLGQ 127
A +K+ ++ G D++ D L+ +F ++ + L+ L
Sbjct: 1054 SACVKVVAAVSMWDVCMERGHRDLEQFERVHRYISDQLFTNFKERTERLVISPLNQLLSM 1113
Query: 128 FPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDL 187
F + KR KL+D+ + E L+ K EE Q A+ +E N L
Sbjct: 1114 FTGPHKLVQKRFDKLLDFYNCTERAEKLKD---------KKTLEELQSARNNYEALNAQL 1164
Query: 188 QEELPSLWSRRVGFYVNTFKNVSSLEAKF 216
+ELP G + N + F
Sbjct: 1165 LDELPKFHQYAQGLFTNCVHGYAEAHCDF 1193
Score = 30.8 bits (68), Expect = 4.1
Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 14/63 (22%)
Query: 590 DFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFT 649
+F + D L L RGD+V+ L G+ + WLQ R +G FP +
Sbjct: 76 EFTSQELDNLPLHRGDLVI--------------LDGIPTAGWLQGRSCWGARGFFPSSCV 121
Query: 650 RRL 652
R L
Sbjct: 122 REL 124
Score = 29.6 bits (65), Expect = 9.1
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 15/83 (18%)
Query: 570 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 629
++ A ++P + + L A +EL + GDV+ + +GV E
Sbjct: 135 SQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITI--------------IGVPEP 180
Query: 630 DWLQYRDLATYKGLFPENFTRRL 652
W + +L +G+FPE F L
Sbjct: 181 GWFE-GELEGRRGIFPEGFVELL 202
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 53.5 bits (127), Expect = 6e-07
Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 17/150 (11%)
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPP- 302
T+ + S P TP P PSP + T SP T P P SP T PP
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPT 1693
Query: 303 ---VPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPE--------VKKEETL 351
P P TP+ + S P ++TTPS P + T
Sbjct: 1694 TTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTS 1753
Query: 352 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLP 381
L P P +TP T SP S T P
Sbjct: 1754 SPLTTTPLPPSITPP-----TFSPFSTTTP 1778
Score = 50.8 bits (120), Expect = 4e-06
Identities = 74/316 (23%), Positives = 92/316 (29%), Gaps = 45/316 (14%)
Query: 260 TPSPPEE-PSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVP----PLPKVTPTKE 314
TPSPP PSP P+ T + T P+ P P T PP+ P P TP+
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP- 1456
Query: 315 LQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHS 374
P + TTP P P P TP+ T +
Sbjct: 1457 ---------------PISTTTTPPPTTTPSPPTTT--------PSPPTTTPSPPTTTTTT 1493
Query: 375 PMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQ-----TDQSMICNLIIPGA 429
P T P T+T + PAS + T P + T T I P
Sbjct: 1494 PPPTTTPSP--PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT 1551
Query: 430 DADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELE 489
T + P T P+ + T TT + P
Sbjct: 1552 STTTLPPTTTPSPP--PTTTTTPPPTTTPSPPTTTTPSPPTITTTTP-PPTTTPSPPTTT 1608
Query: 490 ATVPQEKVIPSV-VIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 548
T P PS P + T P TT PP T P T P
Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1668
Query: 549 IQD-----PQPTPSAP 559
I P TPS+P
Sbjct: 1669 ITTTTTPPPTTTPSSP 1684
Score = 48.9 bits (115), Expect = 1e-05
Identities = 69/321 (21%), Positives = 90/321 (28%), Gaps = 32/321 (9%)
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPP- 302
T+ + S P TP P PSP + T +P T P+ P P T PP
Sbjct: 1415 TLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPT 1474
Query: 303 -VPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL-DLDFDPFK 360
P P TP+ P + TTP P +
Sbjct: 1475 TTPSPPTTTPSP----------------PTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518
Query: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
P TP+ T +P T P T+T + P S + T P T +
Sbjct: 1519 PTTTPSPPTTTTTTPPPTTTPSP--PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576
Query: 421 ICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKI--GTETTEGA 478
+ + + T P P I T TT
Sbjct: 1577 TPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP 1636
Query: 479 ESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSE 538
+ P T P PS P + IT P TT P P +
Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPS---PPTTTTPSP---PITTTTTPPPTT---TPSSPITT 1687
Query: 539 TPELATEQKPIQDPQPTPSAP 559
TP T P TPS+P
Sbjct: 1688 TPSPPTTTMTTPSPTTTPSSP 1708
Score = 39.7 bits (91), Expect = 0.009
Identities = 75/367 (20%), Positives = 113/367 (30%), Gaps = 46/367 (12%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQ 296
T+ P+ +G P+ T +P P+ +PT +P T +P P + +Q
Sbjct: 3930 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQ 3987
Query: 297 TRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLDLD 355
T P+ VTPT + ++ T TP+ + P T +
Sbjct: 3988 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4047
Query: 356 FDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQP--QDTSLFT 413
P TP G+ T +P++ TT+T P G+ T P T++
Sbjct: 4048 -----PTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4094
Query: 414 MQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATV---PAGEGVSLEEAKI 470
T P T P TV P G
Sbjct: 4095 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154
Query: 471 GTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDA 530
T TT + P + T P +V P + G T A E T
Sbjct: 4155 ITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTGPPTHTSTAPIAELTTSN 4213
Query: 531 APP------------GPTSETPELATEQKPIQD-----PQPTPSAPAMGAADQLASAREA 573
PP P +E+ L + P + P TP+AP + S +
Sbjct: 4214 PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPS 4273
Query: 574 SQELPPG 580
+ PPG
Sbjct: 4274 TTTSPPG 4280
Score = 39.3 bits (90), Expect = 0.012
Identities = 35/130 (26%), Positives = 44/130 (33%), Gaps = 34/130 (26%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQEN 319
T P PSP P+ T +P T P+ P P P T PP P TP+ +
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP----PTTTPSSPITTTP 1689
Query: 320 IISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQT 379
P ++TTPS P TP+ T +P S T
Sbjct: 1690 S--------PPTTTMTTPS----------------------PTTTPSSPITTTTTPSSTT 1719
Query: 380 LPWDLWTTST 389
P TT T
Sbjct: 1720 TPSPPPTTMT 1729
Score = 36.6 bits (83), Expect = 0.075
Identities = 71/357 (19%), Positives = 108/357 (30%), Gaps = 41/357 (11%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3907 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3966
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3967 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4022
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQP--QDTSL 411
+ P TP G+ T +P++ TT+T P G+ T P T++
Sbjct: 4023 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 4069
Query: 412 FTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATV---PAGEGVSLEEA 468
T P T P TV P G
Sbjct: 4070 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4129
Query: 469 KIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEI----TIGAEPK 524
T TT + P + T P + + I T+ P
Sbjct: 4130 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4189
Query: 525 ETTEDAAPPGPTSETP--ELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPP 579
T PP TS P EL T P P+ + + + L + LPP
Sbjct: 4190 PTGTQTGPPTHTSTAPIAELTTSNPP---PESSTPQTSRSTSSPLTESTTLLSTLPP 4243
Score = 35.0 bits (79), Expect = 0.22
Identities = 37/163 (22%), Positives = 60/163 (36%), Gaps = 16/163 (9%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPK 308
P + P+ T +P P+ +PT +P T +P P + +QT P+
Sbjct: 1895 PPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTT 1952
Query: 309 VTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLDLDFDPFKPEVTPAG 367
VTPT + ++ T TP+ + P T + P TP G
Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----TPTPTPTG 2007
Query: 368 SAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ T +P++ TT+T P G+ T P T+
Sbjct: 2008 TQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2042
Score = 32.7 bits (73), Expect = 1.1
Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 16/88 (18%)
Query: 262 SPPEEPSPLPSPTASPNHTLAPASPAPARPRS-PSQTRKGPPVPPLPKVTPTKELQQENI 320
S P PSP P+P+ S +P P++P S PS+ G P P P + QEN
Sbjct: 4375 SCPSTPSPTPTPSKS--------TPTPSKPSSTPSKPTPGTKPPECPDFDPPR---QENE 4423
Query: 321 ISFFEDNFVPEISVTTPSQNEVPEVKKE 348
+ D F+ T N V VK E
Sbjct: 4424 TWWLCDCFM----ATCKYNNTVEIVKVE 4447
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 1975 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2034
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2035 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2090
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2091 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2134
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2067 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2126
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2127 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2182
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2183 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2226
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2159 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2218
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2219 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2275 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2318
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2251 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2310
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2311 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2366
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2367 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2410
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2402
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2403 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2458
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2459 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2502
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2435 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2494
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2495 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2550
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2551 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2594
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2587 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2642
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2643 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2686
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2619 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2678
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2679 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2734
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2735 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2778
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2711 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2770
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2771 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2827 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2870
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2803 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2862
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2863 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2918
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2919 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 2962
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2895 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2955 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3010
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3011 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3054
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2987 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3046
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3047 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3102
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3103 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3146
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3139 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3194
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3195 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3238
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3231 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3286
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3287 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3330
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3263 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3322
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3323 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3379 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3422
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3355 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3414
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3415 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3470
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3471 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3514
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3447 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3506
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3507 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3562
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3563 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3606
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3539 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3598
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3599 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3654
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3655 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3698
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3631 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3690
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3691 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3746
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3747 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3790
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3783 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3838
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3839 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3882
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 27/177 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3875 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3930
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3931 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTT 3974
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 53.5 bits (127), Expect = 6e-07
Identities = 84/364 (23%), Positives = 128/364 (35%), Gaps = 41/364 (11%)
Query: 253 GPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPL-PKVTP 311
G +R P E PLP+ A APA+ P+ V PL P+ P
Sbjct: 382 GEIRSPSAQKAPIEVQPLPAEGA--------LEEAPAKVEPPTVEETLADVQPLLPEEAP 433
Query: 312 TKELQQENIISFFE---DNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGS 368
+E ++ + + E + E P + E E LL P + TPA +
Sbjct: 434 REEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPP--ADETPAEA 491
Query: 369 AGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPG 428
SP+S+ + ++ P + ++T+ + ++ + P
Sbjct: 492 ----RSPLSEETSAE--EAHAEVQSPLA----------EETTAEEASAEIQLLAAIEAPA 535
Query: 429 ADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKI------GTETTEGAESAQ 482
+ A + +S E EEA AE + P+ +GVS+EEA + G ETT AE A
Sbjct: 536 DETPAEAQSPLS--EETSAEEAPAEVQS-PSAKGVSIEEAPLELQPPSGEETT--AEEAS 590
Query: 483 PEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPEL 542
+ L AT + P+ V P + P E A P P
Sbjct: 591 AAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 650
Query: 543 ATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQ 602
A E P P APA A Q LP ETL + +D++ +
Sbjct: 651 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAE 710
Query: 603 RGDV 606
V
Sbjct: 711 EASV 714
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/369 (24%), Positives = 134/369 (36%), Gaps = 58/369 (15%)
Query: 239 ADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTR 298
A+ + +Q P++ PL + P+ + PS SP+ + P P+ SPS+
Sbjct: 310 AENSVKVQPPPAEEAPL--VEFPAEIQPPSAEESPSVELLAEILP----PSAEESPSEEP 363
Query: 299 KGPPVPPLPKVTPTKELQQENIISFFEDNFVPEIS--------VTTPSQNEVPEVKKEET 350
+PP + +P+ EL E I S E+ P++ E P V EET
Sbjct: 364 PAEILPPPAEKSPSVELLGE-IRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTV--EET 420
Query: 351 LLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
L D+ P PE P A + P + T+ P P++T+
Sbjct: 421 LADV--QPLLPEEAPREEARELQLSTAMETPAE--EAPTEFQSPL----------PKETT 466
Query: 411 LFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKI 470
+ ++ P + A + +S E EEA AE + P E + EEA
Sbjct: 467 AEEASAEIQLLAATEPPADETPAEARSPLS--EETSAEEAHAEVQS-PLAEETTAEEASA 523
Query: 471 GTETTEG---------AESAQPEAEELEA-TVPQEKVIPS----------VVIEPASNHE 510
+ AE+ P +EE A P E PS + ++P S E
Sbjct: 524 EIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEE 583
Query: 511 EEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASA 570
E E + + TE +A P P A E P P AP A Q A
Sbjct: 584 TTAE-EASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAP---AEVQPPPA 639
Query: 571 REASQELPP 579
EA E+ P
Sbjct: 640 EEAPAEVQP 648
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 52.4 bits (124), Expect = 1e-06
Identities = 76/332 (22%), Positives = 132/332 (39%), Gaps = 42/332 (12%)
Query: 12 NVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQ 71
++Q+RLN+ Q + LQK ++ ++EQ E +Q +++ E + L+ ELR A ++
Sbjct: 105 SLQQRLNQFQHE-LQK----NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHL 159
Query: 72 EASMKLTESLHE---VYEPDWYGREDVKMVGEKCDVLWEDFHQ-KLVDGSLLTLDTYLGQ 127
L + L + + + + C L D H L GS L+ + G
Sbjct: 160 RQICGLEQQLRQQQGLQDAAFSNLSPPPAPAPPCTDL--DLHYLALRGGSGLSHAGWPGS 217
Query: 128 FPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDL 187
P + + +R + ++ +A+ Q + + ++ + + E ++ Q+ +
Sbjct: 218 TPSVSDLERRRLEEALE--AAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASN 275
Query: 188 QEELPSLWSRRVG--------FYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHA 239
Q E W +RVG Y + + L + +L L E G +H+
Sbjct: 276 QSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHS 335
Query: 240 DKAFTIQGAP---SDSGPLRIAKTPSP-----PEEPSPLPSPTASPNHTLAPASPA---- 287
+ AP S S P R A P P+ SP+P P SP +PASP+
Sbjct: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVP-PCPSPQQRRSPASPSCPSP 394
Query: 288 --------PARPRSPSQTRKGPPVPPLPKVTP 311
P +SPS R+ P P P P
Sbjct: 395 VPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQP 426
>gi|8923904 bridging integrator 3 [Homo sapiens]
Length = 253
Score = 51.2 bits (121), Expect = 3e-06
Identities = 46/220 (20%), Positives = 104/220 (47%), Gaps = 17/220 (7%)
Query: 33 ETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGR 92
+T + FE ++ E + RLQ++++ A M ++++K+ SL + P
Sbjct: 18 KTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKI--SLDLLSNPLCEQD 75
Query: 93 EDVKMVGEKCDVL---WEDFHQKLVDGSLLT----LDTYLGQFPDIKNRIAKRSRKLVDY 145
+D+ + D + F+Q+ V+ T L + FP + + +R + L DY
Sbjct: 76 QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY 135
Query: 146 DSARHHLEALQSSKRKDE--SRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYV 203
+ +E + ++ +++ +A EE + ++ FE N L EE+P + R+ ++
Sbjct: 136 RRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQ 195
Query: 204 NTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQ--HADK 241
+F+++ + ++ E+ HK++ ++ DQ H+D+
Sbjct: 196 PSFESLIRAQVVYYSEM----HKIFGDLSHQLDQPGHSDE 231
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 50.8 bits (120), Expect = 4e-06
Identities = 85/334 (25%), Positives = 119/334 (35%), Gaps = 48/334 (14%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPAS--PAPARPRSPSQTRKGPPVPPL 306
P+ P A PPEEP+ + +P +PA+ P P P SP+ P P
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
Query: 307 PKV---TPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEV---KKEETLLDLDFDPFK 360
P TP + + E+ P +V TP + P EE P
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP 1140
Query: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
E PA A +P T + PA+ P +++ F ++
Sbjct: 1141 EE--PAFPAPAVPTPEESASAAVAVPTPEESASPAA-----AVPTPAESASFA-----AV 1188
Query: 421 ICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAG-EGVSLEEAKIGTETTEGAE 479
+ L P + A A+V T AA A EE + A+VP E SL A E
Sbjct: 1189 VATLEEPTSPA-ASVPT--PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPA 1245
Query: 480 SAQPEAEELEAT-----VPQEKVIPSVVI----EPASNHEEEGENEITIGAEPKETTEDA 530
+A P EE ++ P+E P+ + EPAS A E+
Sbjct: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS------------PAAAVSNLEEP 1293
Query: 531 APPGPTSETPELATEQKPIQDPQPTPSAPAMGAA 564
A P TPE+A PTP PA+ AA
Sbjct: 1294 ASPAAAVPTPEVAAIPAA---SVPTPEVPAIPAA 1324
Score = 47.8 bits (112), Expect = 3e-05
Identities = 86/374 (22%), Positives = 127/374 (33%), Gaps = 32/374 (8%)
Query: 209 VSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDS---GPLRIAKTPSPPE 265
VSS E A + + + + A A T+ D GP+ A T PE
Sbjct: 926 VSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPE 985
Query: 266 EPSPLPSPTASPNHTLAPAS--PAPARPRSPSQTRKGP--PVPPLPKVTPTKE-LQQENI 320
EP ++P +PA+ P P P SP+ P P P V P +E
Sbjct: 986 EPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA 1045
Query: 321 ISFFEDNFVPEISVTTPSQNEVPEV---KKEETLLDLDFDPFKPEVTPAGSAGVTHSPMS 377
+ E+ P +V TP + P EE P E P A +P
Sbjct: 1046 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE--PTSPAAAVPTPEE 1103
Query: 378 QTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGT 437
T P T + PA+ + +P + ++ +P + A+
Sbjct: 1104 PTSPAAAVPTPEEPASPAA--AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161
Query: 438 LVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKV 497
V P E A A E S E ++ P + AT+ +E
Sbjct: 1162 AVP----TPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATL-EEFT 1216
Query: 498 IPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP----PGPTSETPELATEQKPIQDPQ 553
P+ + P S EE + + P+E T AA PTS + T ++ + P
Sbjct: 1217 SPAASV-PTS---EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEE-LSSPA 1271
Query: 554 ---PTPSAPAMGAA 564
PTP PA AA
Sbjct: 1272 ASVPTPEEPASPAA 1285
Score = 38.1 bits (87), Expect = 0.026
Identities = 35/147 (23%), Positives = 47/147 (31%)
Query: 430 DADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELE 489
+ AAV + S E AP A + + A G S E A + E PE
Sbjct: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
Query: 490 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPI 549
AT P S EE + + T+ AA P P T A P
Sbjct: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE 1037
Query: 550 QDPQPTPSAPAMGAADQLASAREASQE 576
+ P + P A+A +E
Sbjct: 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEE 1064
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 50.8 bits (120), Expect = 4e-06
Identities = 70/299 (23%), Positives = 111/299 (37%), Gaps = 47/299 (15%)
Query: 263 PPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIIS 322
PP E P P A P T+ P P P + ++P+ K P +PP+ KE+ E +
Sbjct: 10677 PPAEVVEEPEPAAPPQVTVPPKKPVPEK-KAPAVVAKKPELPPVKVPEVPKEVVPEKKVP 10735
Query: 323 FFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPW 382
VP+ P+ +VPEV KE P KPEV PA V P+ + P
Sbjct: 10736 L----VVPKKPEAPPA--KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKP- 10788
Query: 383 DLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAA 442
+ + + A + +P++ I P + V A
Sbjct: 10789 -----AVPVPERAESPPPEVYEEPEE----------------IAPEEEIAPEEEKPVPVA 10827
Query: 443 EGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVV 502
E EE E VP + E K+ + E+ P+ E E + + K+ P
Sbjct: 10828 E---EEEPEVPPPAVPEEPKKIIPEKKV--PVIKKPEAPPPKEPEPEKVIEKPKLKPRPP 10882
Query: 503 IEPASNHEEEGENEI-TIGAEPKETTEDAAP------------PGPTSETPELATEQKP 548
P + +E+ + +I + A PK+ + PG + +L E+KP
Sbjct: 10883 PPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKP 10941
Score = 49.3 bits (116), Expect = 1e-05
Identities = 97/404 (24%), Positives = 137/404 (33%), Gaps = 72/404 (17%)
Query: 170 EEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYE 229
EEEF + ++ FEE EE L RV K H+ I V + E
Sbjct: 10380 EEEFHEVEEYFEEGEFHEVEEFIKLEQHRV--------EEEHRVEKVHRVIEVFEAEEVE 10431
Query: 230 VMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPA 289
V K AP GP I++ PP++P P P P P
Sbjct: 10432 VFEK------------PKAP-PKGP-EISEKIIPPKKPPTKVVPRKEP-PAKVPEVPKKI 10476
Query: 290 RPRSPSQTRKGPPVPP--LPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ + P VPP +P+V P KE+ E + VP +VPE K
Sbjct: 10477 VVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVP------VPPAKKPEAPPPKVPEAPK 10530
Query: 348 E---ETLLDLDFDPFKPEVTP-----AGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGS 399
E E + + P KPEV P A V + + +P
Sbjct: 10531 EVVPEKKVPVP-PPKKPEVPPTKVPEVPKAAVPEKKVPEAIP------------------ 10571
Query: 400 FNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPA 459
+P+ + + ++ +P A T V E AP E +K VP
Sbjct: 10572 ----PKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPE-APKEVVPEKKVPVPP 10626
Query: 460 GEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQ-EKVIPSVVIEPASNHEEEGENEIT 518
+ + K+ E + A PE + EA P+ E P V EP EE E+
Sbjct: 10627 PKKPEVPPTKV----PEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVV 10682
Query: 519 IGAEPKETTEDAAPPG---PTSETPELATEQKPIQDPQPTPSAP 559
EP + PP P + P + +KP P P P
Sbjct: 10683 EEPEPAAPPQVTVPPKKPVPEKKAPAVVA-KKPELPPVKVPEVP 10725
Score = 47.4 bits (111), Expect = 4e-05
Identities = 86/351 (24%), Positives = 123/351 (35%), Gaps = 59/351 (16%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQT----------- 297
P + P + PP+ SP P +P + A P+ P T
Sbjct: 10557 PKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEV 10616
Query: 298 --RKGPPVPP--LPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLD 353
K PVPP P+V PTK + + + VPE P ++ PEV +E +
Sbjct: 10617 VPEKKVPVPPPKKPEVPPTKVPEVPKVA--VPEKKVPEAIPPKP-ESPPPEVFEEPEEVA 10673
Query: 354 LDFDPFK--PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL 411
L+ P + E PA VT P P +P+ +
Sbjct: 10674 LEEPPAEVVEEPEPAAPPQVTVPPKKPV--------------PEKKAPAVVAKKPELPPV 10719
Query: 412 FTMQTDQSMICN----LIIPG------ADADAAVGTLVSAAEGAPGEEAEAEKATVPAGE 461
+ + ++ L++P A +V + A ++ E A VP
Sbjct: 10720 KVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVP 10779
Query: 462 GVSLEEAKIGTETTEGAESAQPEA-EELEATVPQEKVIPSVVIEPASNHEEEGENEITIG 520
+ E K E AES PE EE E P+E++ P +P EEE E E+
Sbjct: 10780 KKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE-KPVPVAEEE-EPEVPPP 10837
Query: 521 AEPKE----TTEDAAP-------PGPTSETPELATEQKPIQDPQPTPSAPA 560
A P+E E P P P PE E KP P+P P PA
Sbjct: 10838 AVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIE-KPKLKPRPPPPPPA 10887
Score = 46.2 bits (108), Expect = 9e-05
Identities = 75/339 (22%), Positives = 115/339 (33%), Gaps = 43/339 (12%)
Query: 289 ARPRSPSQTRKG-PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
A P+ P + K PP P KV P KE + + V E V P + VP K
Sbjct: 10438 APPKGPEISEKIIPPKKPPTKVVPRKEPPAK--VPEVPKKIVVEEKVRVPEEPRVPPTKV 10495
Query: 348 EETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQ 407
E L + P K P P P ++ V P +P+
Sbjct: 10496 PEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPK--------KPE 10547
Query: 408 DTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEE 467
+ ++ + +P A + E P E EA K VP E
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEA--------IPPKPESPPPEVPEAPKEVVP--------E 10591
Query: 468 AKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGEN--EITIGAEPKE 525
K+ + E + E V EK +P + P E E+ A P++
Sbjct: 10592 KKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVP---VPPPKKPEVPPTKVPEVPKVAVPEK 10648
Query: 526 TTEDAAPPGPTSETPEL--ATEQKPIQDP------QPTPSAPAMGAADQLASAREASQEL 577
+A PP P S PE+ E+ +++P +P P+AP + + ++
Sbjct: 10649 KVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT---VPPKKPVPEKK 10705
Query: 578 PPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEA 616
P + K L + + + V LVVP EA
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA 10744
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/350 (22%), Positives = 130/350 (37%), Gaps = 52/350 (14%)
Query: 249 PSDSGPLRIAKTPSP-PEEPSPLP-----SPTASPNHTLAPASPAPARP----RSPSQTR 298
PS + ++A+ SP P SP P +PT SP +++PA+ P RSP R
Sbjct: 269 PSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMR 328
Query: 299 K--------GPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEET 350
K GP VPP P K QE ++ + + E ++TT +Q E +
Sbjct: 329 KTQASTVATGPEVPP-----PWK---QEGYVASSSEAEMRETTLTTSTQIRTEERWEGRY 380
Query: 351 LLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
+ +VT +G+AG S + + + + V + + +
Sbjct: 381 -------GVQEQVTISGAAGAAASVSASA------SYAAEAVATGAKEVKQDADKSAAVA 427
Query: 411 LFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEE---AEAEKATVP----AGEGV 463
D + + +I + A T +A P +E EAEK V A +
Sbjct: 428 TVVAAVDMARVREPVISAVE-QTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKA 486
Query: 464 SLEEAKIGTETTEGAESAQPEAEELEATVPQEKV-IPSVVIEPASNHEEEGENEITIGAE 522
+E K T+ + Q + EK +P VVI A E+E I +
Sbjct: 487 KEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKEQETRISEEITKK 546
Query: 523 PKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASARE 572
K+ T++A ET A + + T GA ++ + ++
Sbjct: 547 QKQVTQEAI----RQETEITAASMVVVATAKSTKLETVPGAQEETTTQQD 592
Score = 41.2 bits (95), Expect = 0.003
Identities = 127/670 (18%), Positives = 223/670 (33%), Gaps = 115/670 (17%)
Query: 14 QKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEA 73
+K + + +E V +K + K E + + + E E E Y + +E
Sbjct: 9045 KKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEI 9104
Query: 74 SMKLTESLHEVYEPD------WYGREDVKMVGEK--------------CDVLWEDFHQKL 113
++ + +HE +E D +Y RE+ GE+ ++E+ H++
Sbjct: 9105 KVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERK 9164
Query: 114 VDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESR--ISKAEE 171
V + P I K + ++ S R E +Q +K + S+ + +
Sbjct: 9165 VPAKVPEKKA-----PPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPS 9219
Query: 172 EFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVM 231
++V E + + + ++ F +T + VS + KEI V K++ +
Sbjct: 9220 RTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEI-VTEEKIHVAI 9278
Query: 232 TKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARP 291
+K + + P P +A P P + P P P P P
Sbjct: 9279 SK----RVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPE------VPKKPVPEEK 9328
Query: 292 RSPSQTRKGPPVPPLPKVTPTKELQQENI--------------ISFFEDNFVPEISVTTP 337
+ +K P PP P K + +E I + + V E +T
Sbjct: 9329 KPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIV 9388
Query: 338 SQNE------VPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDL 391
+Q E VPE+ K++ P + + P V P LP
Sbjct: 9389 TQREESPPPAVPEIPKKKV-------PEERKPVPRKEEEVPPPPKVPALP---------- 9431
Query: 392 VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEE-- 449
+P P++ + + P A+ + T+V E+
Sbjct: 9432 KKPV----------PEEKVAVPVPVAKK------APPPRAEVSKKTVVEEKRFVAEEKLS 9475
Query: 450 -AEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASN 508
A ++ V E VS EE +E EG + EE E E V+ EP
Sbjct: 9476 FAVPQRVEVTRHE-VSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEY 9534
Query: 509 HEEEGENEIT--IGAEPKETTE----------------DAAPPGPTSETPELATEQKPIQ 550
EE + I+ + AEP E TE + PP E P+ +K +
Sbjct: 9535 VVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVP 9594
Query: 551 DPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVV 610
P P + +++PP + E L + + + + VLV
Sbjct: 9595 APVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLP--AKVTERHMQITQEEKVLVA 9652
Query: 611 PSDSEADQDA 620
+ EA A
Sbjct: 9653 VTKKEAPPKA 9662
Score = 36.2 bits (82), Expect = 0.098
Identities = 76/365 (20%), Positives = 127/365 (34%), Gaps = 64/365 (17%)
Query: 207 KNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPP-- 264
K + E F +E+ + Y V + H ++ F + P+++ + P P
Sbjct: 9901 KELEPEEVAFEEEVVTHVEE-YLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVP 9959
Query: 265 EEPSPLPSPTASPNHTLAPASPAPARPRSPSQT-------RKGPPVPPLPKVTPTKELQQ 317
EE P+P P AP + P P+ P + ++ PP +P+V P K + +
Sbjct: 9960 EEKKPVPVPKKKE----APPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEV-PKKPVPE 10014
Query: 318 ENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMS 377
E + VP +VPEV K+ + + P+ A A V P
Sbjct: 10015 EKVP-------VPVPKKVEAPPAKVPEVPKKP-VPEKKVPVPAPKKVEAPPAKVPEVP-K 10065
Query: 378 QTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGT 437
+ +P + T A +P + Q ++ + I+P
Sbjct: 10066 KLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVP---------- 10115
Query: 438 LVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKV 497
E+ +P E V EE ++ E E PE EE+ P+E+
Sbjct: 10116 ---------------EEEVLPEEEEVLPEEEEVLPEE----EEVLPEEEEIP---PEEEE 10153
Query: 498 IPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQK---PIQDPQP 554
+P E E E+ +PK P P E + TE+K P ++ P
Sbjct: 10154 VPPEEEYVPEEEEFVPEEEVLPEVKPK-----VPVPAPVPEIKKKVTEKKVVIPKKEEAP 10208
Query: 555 TPSAP 559
P
Sbjct: 10209 PAKVP 10213
Score = 34.7 bits (78), Expect = 0.28
Identities = 78/339 (23%), Positives = 116/339 (34%), Gaps = 58/339 (17%)
Query: 251 DSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGP-PVPPLPKV 309
++ P ++ + P PEE P+ P P + P P+ P K P PVP +
Sbjct: 9972 EAPPAKVPEVPKKPEEKVPV----LIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEA 10027
Query: 310 TPTKELQQENIISFFEDNFVPE--ISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAG 367
P K + VPE + V P + E P K E L + KP P
Sbjct: 10028 PPAK-------VPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKK 10080
Query: 368 SAGVTHS--------PMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419
P+ LP + + + P P++ + + +
Sbjct: 10081 VEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEE------VLPEEEEVLPEEEEVL 10134
Query: 420 MICNLIIPGADADAAVGTLVSAAEGAPGEEAE---------AEKATVPAGEGV-----SL 465
++P + V E EE E K VP V +
Sbjct: 10135 PEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKV 10194
Query: 466 EEAKIGTETTEGAESAQ-PEA----EELEATVP-QEKVIPSVVIEPASNHEEEGENEITI 519
E K+ E A A+ PE EE +P +E+V+P +E EEE +E I
Sbjct: 10195 TEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLP---VEVTEEPEEEPISEEEI 10251
Query: 520 GAEPK--ETTEDAAPPGPTSETPELATEQKPIQDPQPTP 556
EP E E+ APP PE+ + P + P P P
Sbjct: 10252 PEEPPSIEEVEEVAPP----RVPEVIKKAVP-EAPTPVP 10285
Score = 34.7 bits (78), Expect = 0.28
Identities = 32/107 (29%), Positives = 46/107 (42%), Gaps = 17/107 (15%)
Query: 248 APSDSGPLRIAKTPSP-------PEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
AP + P+ +A+ P PEEP + P P +P P P P + +
Sbjct: 10817 APEEEKPVPVAEEEEPEVPPPAVPEEPKKI-IPEKKVPVIKKPEAPPPKEPE-PEKVIEK 10874
Query: 301 P---PVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPE 344
P P PP P P KE +E I F+ +P+ V P + +VPE
Sbjct: 10875 PKLKPRPPPPPPAPPKEDVKEKI---FQLKAIPKKKV--PEKPQVPE 10916
Score = 33.5 bits (75), Expect = 0.63
Identities = 35/126 (27%), Positives = 46/126 (36%), Gaps = 20/126 (15%)
Query: 259 KTPSPPEEPSPLPSPTAS-------------PNHTLAPASPAPARPRSPSQTRKGPP-VP 304
K P+ EEP P P A P P P P+ P +K PP V
Sbjct: 9567 KIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVI 9626
Query: 305 PLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK----EETLLDLDFDPFK 360
+ + P K ++ I+ E V P + VPE K EE +L L P +
Sbjct: 9627 KMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKL--KPKR 9684
Query: 361 PEVTPA 366
E PA
Sbjct: 9685 EEEPPA 9690
Score = 33.5 bits (75), Expect = 0.63
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 7/64 (10%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPA-----RPRSPSQTRKGPPV 303
P P+ + P+ + +P PT P + PA P PA +P + +T K PPV
Sbjct: 10980 PPPPKPVEEVEVPTVTKRERKIPEPTKVPE--IKPAIPLPAPEPKPKPEAEVKTIKPPPV 11037
Query: 304 PPLP 307
P P
Sbjct: 11038 EPEP 11041
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/107 (24%), Positives = 36/107 (33%), Gaps = 4/107 (3%)
Query: 263 PPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIIS 322
P +P P P P + K P VP P P +E++ +
Sbjct: 10937 PERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTK 10996
Query: 323 ----FFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTP 365
E VPEI P P+ K E + + P +PE TP
Sbjct: 10997 RERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTP 11043
Score = 31.2 bits (69), Expect = 3.1
Identities = 35/117 (29%), Positives = 51/117 (43%), Gaps = 22/117 (18%)
Query: 202 YVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAK-- 259
Y +TF+ +SS++A +V+ V G Q A+ TIQ A R+ +
Sbjct: 32614 YKSTFE-ISSVQASDEGNYSVV------VENSEGKQEAEFTLTIQKA-------RVTEKA 32659
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
SPP SP P SP A +P R +SP + P K TPT+++Q
Sbjct: 32660 VTSPPRVKSPEPR-VKSPE-----AVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQ 32710
Score = 30.4 bits (67), Expect = 5.4
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 11/86 (12%)
Query: 500 SVVIEPASNHEEEGENEITIGAEPKETTEDAAP-------PGPTSETPELATEQKPIQDP 552
SVV+E N E + E E T+ + TE A P P ++PE K ++ P
Sbjct: 32632 SVVVE---NSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSP 32688
Query: 553 QPTPSAPAMGAADQLASAREASQELP 578
+P+ A+ + + E Q LP
Sbjct: 32689 EPS-HPKAVSPTETKPTPTEKVQHLP 32713
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 50.4 bits (119), Expect = 5e-06
Identities = 54/182 (29%), Positives = 80/182 (43%), Gaps = 20/182 (10%)
Query: 442 AEGAPGEEA-EAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPS 500
++GA G EA EAE P EGV EA+ + EG AQPE+E++EA + + P
Sbjct: 1829 SDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEG--EAQPESEDVEAPEAEGEAQPE 1886
Query: 501 V--VIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 558
V P + E + E+E GAE E ++A P + E E E +P +
Sbjct: 1887 SEDVETPEAEWEVQPESE---GAEAPEAEKEAQPETESVEALETEGEDEPESE------- 1936
Query: 559 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ 618
GA Q A EA+QE + E + EA + + + + V EA+
Sbjct: 1937 ---GAEAQ--EAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 619 DA 620
+A
Sbjct: 1992 EA 1993
Score = 50.4 bits (119), Expect = 5e-06
Identities = 46/157 (29%), Positives = 66/157 (42%), Gaps = 10/157 (6%)
Query: 430 DADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAES------AQP 483
+ A G +E +EAE E P EGV EA+ + EG E+ AQP
Sbjct: 2070 EVQEAEGEAHPESEDVDAQEAEGEAQ--PESEGVEAPEAEGEAQKAEGIEAPETEGEAQP 2127
Query: 484 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELA 543
E+E +EA + + P A + E E + E + G E +E E+A P E PE
Sbjct: 2128 ESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPE-SEGIEAQEAEEEAQPELEGVEAPEAE 2186
Query: 544 TEQKPIQDPQPTPSAPAMGAAD-QLASAREASQELPP 579
E +P + P A + + A EA +E P
Sbjct: 2187 GEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQP 2223
Score = 49.7 bits (117), Expect = 9e-06
Identities = 47/162 (29%), Positives = 66/162 (40%), Gaps = 30/162 (18%)
Query: 428 GADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKI-------GTETTEGAES 480
G +A A G +EG ++AE E P EG+ +EA+ G E E
Sbjct: 2131 GIEAPEAEGEAQPESEGVEAQDAEGEAQ--PESEGIEAQEAEEEAQPELEGVEAPEAEGE 2188
Query: 481 AQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETP 540
AQPE+E +EA P + E + E E G E E E+A P ETP
Sbjct: 2189 AQPESEGIEA--------------PEAEGEAQPELE---GVEAPEAEEEAQPEPEGVETP 2231
Query: 541 ELATEQKPIQDPQ---PTPSAPAMGAAD-QLASAREASQELP 578
E E +P + + +P + D Q A E+S +P
Sbjct: 2232 EAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVP 2273
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
Query: 448 EEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQ-EKVIPSVVIEPA 506
E EAE+ P E V E ++ T+ EG AQPE+E++EA + E +P
Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQEAEG--EAQPESEDVEAPEAEGEMQEAEEEAQPE 2019
Query: 507 SNHEE-----EGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAM 561
S+ E EGE + E ++T DA P E PE E + + A
Sbjct: 2020 SDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAH 2079
Query: 562 GAADQLASAREASQELPP 579
++ + A+EA E P
Sbjct: 2080 PESEDV-DAQEAEGEAQP 2096
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 34/170 (20%)
Query: 428 GADADAAVGTLVSAAEGAPGEEAE--------------AEKATVPAGEGVSLEEAK---- 469
G +A A G +EG +EAE AE P EG+ EA+
Sbjct: 2147 GVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQ 2206
Query: 470 ---IGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKET 526
G E E E AQPE E +E + + P E + E++G ++++G E
Sbjct: 2207 PELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPE--SEGETQGEKKGSPQVSLGDGQSEE 2264
Query: 527 TEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQL--ASAREAS 574
+++ P P E +P P P P Q +S+R +S
Sbjct: 2265 ASESSSPVP---------EDRPTPPPSPGGDTPHQRPGSQTGPSSSRASS 2305
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 10/154 (6%)
Query: 428 GADADAAVGTLVSAAEGAPGE-EAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAE 486
G +A A G A+ A GE + E+E P EG + E++ ET E QPE+E
Sbjct: 1850 GVEAPEAEGD----AQEAEGEAQPESEDVEAPEAEGEAQPESE-DVETPEAEWEVQPESE 1904
Query: 487 ELEATVPQEKVIPSVVIEPASNHEEEGENE-ITIGAEPKETTEDAAPPGPTSETPELATE 545
EA +++ P E E EGE+E + GAE +E E+AA PE
Sbjct: 1905 GAEAPEAEKEAQPET--ESVEALETEGEDEPESEGAEAQE-AEEAAQEAEGQTQPESEVI 1961
Query: 546 QKPIQDPQPTPSAPAMGAADQLASAREASQELPP 579
+ + + P + + A + +EA E P
Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQEAEGEAQP 1995
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/168 (26%), Positives = 65/168 (38%), Gaps = 23/168 (13%)
Query: 430 DADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSL----EEAKIGTETTEGAESA---Q 482
D +A + E E EAE P EG +EA+ TE+ E E+ +
Sbjct: 1873 DVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDE 1932
Query: 483 PEAEELEA-------------TVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTED 529
PE+E EA T P+ +VI S E + E E + + E +E +
Sbjct: 1933 PESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGE 1992
Query: 530 AAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQEL 577
A P E PE E +Q+ + + G Q S E +QE+
Sbjct: 1993 AQPESEDVEAPEAEGE---MQEAEEEAQPESDGVEAQPKSEGEEAQEV 2037
Score = 41.6 bits (96), Expect = 0.002
Identities = 40/149 (26%), Positives = 58/149 (38%), Gaps = 18/149 (12%)
Query: 437 TLVSAAEGAPGEEAEAEKATVPAG-----EGVSLEEAKIGTETTEGAESAQPEAEELEAT 491
T + EG EEA+ E+ G EGV LEE K G E G + E E
Sbjct: 1341 TKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPE--GGLQGEALEEGLKEEG 1398
Query: 492 VPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQD 551
+P+E + + AS+ + +G E +P + E P TE
Sbjct: 1399 LPEEGSVHGQELSEASSPDGKGSQE----DDPVQEEEAGRASASAEPCPAEGTE------ 1448
Query: 552 PQPTPSAPAMGAADQLASAREASQELPPG 580
+PT + D AS R++ +L PG
Sbjct: 1449 -EPTEPPSHLSETDPSASERQSGSQLEPG 1476
Score = 41.2 bits (95), Expect = 0.003
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 427 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLE---EAKIGTETTEGAES--- 480
PG +D A G AEG E+E +A P EG + E EA+ +E E E+
Sbjct: 1826 PG-QSDGAEGIEAPEAEGEAQPESEGVEA--PEAEGDAQEAEGEAQPESEDVEAPEAEGE 1882
Query: 481 AQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETP 540
AQPE+E++E + +V P A E+E + E T E ET + P +E
Sbjct: 1883 AQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPE-TESVEALETEGEDEPESEGAEAQ 1941
Query: 541 ELATEQKPIQDPQPTPSAPAMGAADQLASAREASQEL 577
E A E + Q P + + + + A+ S+++
Sbjct: 1942 E-AEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDV 1977
Score = 40.0 bits (92), Expect = 0.007
Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 33/179 (18%)
Query: 430 DADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEG----------AE 479
+A A G + A E A E E P EG +E + T+ TEG A
Sbjct: 2001 EAPEAEGEMQEAEEEAQPESDGVEAQ--PKSEGEEAQEVEGETQKTEGDAQPESDGVEAP 2058
Query: 480 SAQPEAEELEATV--------PQEKVIPSVVIE----PASN----HEEEGENEITIGAEP 523
A+ EA+E E V P+ + + + E P S E EGE + G E
Sbjct: 2059 EAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEA 2118
Query: 524 KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAA---DQLASAREASQELPP 579
ET +A P E PE E +P + + + A G A + A+EA +E P
Sbjct: 2119 PETEGEAQPESEGIEAPEAEGEAQP--ESEGVEAQDAEGEAQPESEGIEAQEAEEEAQP 2175
Score = 33.1 bits (74), Expect = 0.83
Identities = 30/122 (24%), Positives = 44/122 (36%), Gaps = 16/122 (13%)
Query: 440 SAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIP 499
+ +G+ E+ +A + + G E E AQPE+E +EA
Sbjct: 1803 TGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEA--------- 1853
Query: 500 SVVIEPASNHEEEGENEITIGAEPKETTE---DAAPPGPTSETPELATEQKPIQDPQPTP 556
A +E E E +E E E +A P ETPE E +P + P
Sbjct: 1854 ----PEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAP 1909
Query: 557 SA 558
A
Sbjct: 1910 EA 1911
Score = 32.0 bits (71), Expect = 1.8
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 14/112 (12%)
Query: 202 YVNTFKNVSSLEAKFHKEIAVLC--HKLYEVMTKLGDQHADKAFTIQGAPSDS-----GP 254
Y + K V SL+A H ++C H+ + + + +A T+ G S + GP
Sbjct: 197 YTTSGKKVDSLQALLHSPSVLVCAGHEAFRTPA-MKNARRSEAETLSGLTSRNKNGSWGP 255
Query: 255 LR---IAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPV 303
+ + SPP LP P + P PAP R + + GP V
Sbjct: 256 KTKPSVIHSRSPPGSTPRLPE---RPGPSNPPVGPAPGRHPQDTPAQSGPLV 304
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 50.4 bits (119), Expect = 5e-06
Identities = 81/344 (23%), Positives = 118/344 (34%), Gaps = 38/344 (11%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPL-P 307
PS G + P P+ PS P T PA P SP P V PL P
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP-SPKGDPTSPAVIPLSP 1412
Query: 308 KVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEV---KKEETLLDLDFDPFKPEVT 364
K P + +E + + + P +VT S + P K DP P VT
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPP-AVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 365 PAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNL 424
P SP P + T+S+ PA+ T P + + +
Sbjct: 1472 PP-------SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA-----VIPSSPKEVPAT 1519
Query: 425 IIPGADADAAVGTLVS---AAEGAPGEEAEAEKATVPAGEGV-SLEEAKIGTETTEGAES 480
D A TL+S A AP E TVP+ + ++ K T E+
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579
Query: 481 AQPEAEELE----ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPT 536
+ P A A P+E +IP V P+ P T + GP
Sbjct: 1580 SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE----------APTPPAVTPPSPEKGPA 1629
Query: 537 SETPELATEQKPI--QDPQPTPSAPAMGAADQLASAREASQELP 578
+ P+ P+ + +P++PA A+ +AS+ LP
Sbjct: 1630 TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673
Score = 45.4 bits (106), Expect = 2e-04
Identities = 81/361 (22%), Positives = 123/361 (34%), Gaps = 37/361 (10%)
Query: 249 PSDSG-PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAP--------ARPRSPSQTRK 299
PS G P A TP P+EP S + APA+PAP P SP +
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA 1518
Query: 300 GP-----PVPP----LPKVTPTKELQQENIISFFEDNFVPEISVTTPSQN-EVPEVKKEE 349
P P+ P L K TP +E +I P ++V +P + +P K+
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIP-------PAMTVPSPKKTPAIPTPKEAP 1571
Query: 350 TLLDLDFDPFKPEVTPAGSAGVTHS-----PMSQTLPWDLWTTSTDLVQPASGGSFNGFT 404
P VTP+ G P + T P + V P S
Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP 1631
Query: 405 QPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAP---GEEAEAEKATVPAGE 461
P+ T T S+ + P + T+ A++G P G A E PA E
Sbjct: 1632 APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE 1691
Query: 462 GVSLEEA--KIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITI 519
+ A + G +T + + ++ P + A + + +V P +++
Sbjct: 1692 STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG 1751
Query: 520 GAEPKETTEDAAPPGPTSETP-ELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELP 578
APP + TP A +K + P+ + A L A LP
Sbjct: 1752 KDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLP 1811
Query: 579 P 579
P
Sbjct: 1812 P 1812
Score = 45.4 bits (106), Expect = 2e-04
Identities = 84/377 (22%), Positives = 126/377 (33%), Gaps = 45/377 (11%)
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAP-ARPRSPSQTRKGPP 302
T +GAPS L SP + +P P P+ PA+PAP P SP P
Sbjct: 1589 TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP------PV 1642
Query: 303 VPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPE 362
P K +PT + ++ T P ++ KK T L PE
Sbjct: 1643 TPSSLKDSPTSPA-----------SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE 1691
Query: 363 VTPAGSAGVTHSPMSQTLPWDLWTTSTDLV--QPASGGSFNGFTQPQDTSLFTMQTDQSM 420
TP +A P ++ TS + A GS + L +Q D S
Sbjct: 1692 STPIITAPTRKGPQTKKSS----ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747
Query: 421 ICNLIIPGADADAAVGTLVSAAEGAPGE--EAEAEKATVPAGEGVSLEEAKIGTETTEGA 478
G DA + ++ E A A + +P E S+ A + A
Sbjct: 1748 TAK----GKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803
Query: 479 ESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSE 538
S P + +P P +V+E S + + + P E P S
Sbjct: 1804 PSPVPTLPPKQQFLPSS---PGLVLESPSKPLAPADEDELLPLIPPEPISGGVP--FQSV 1858
Query: 539 TPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDE 598
+ T K P PTPSA + S E+ + E++ + E +S +
Sbjct: 1859 LVNMPT-PKSAGIPVPTPSAKQPVTKNNKGSGTESDSD---------ESVPELEEQDSTQ 1908
Query: 599 LTLQRGDVVLVVPSDSE 615
T Q+ + D E
Sbjct: 1909 ATTQQAQLAAAAEIDEE 1925
Score = 43.9 bits (102), Expect = 5e-04
Identities = 81/320 (25%), Positives = 103/320 (32%), Gaps = 61/320 (19%)
Query: 246 QGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPP 305
+G P+ P + A TP PSP SP A+P A PA A P SP + P P
Sbjct: 997 KGGPATPSP-KGAPTPPAVTPPSPKGSPAATPFPKGASTPPA-ATPPSP---KGSPAATP 1051
Query: 306 LPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTP 365
LPK P TTP+ +P K L P P TP
Sbjct: 1052 LPKGAP-----------------------TTPAAT-LPSPKGGPATPSLKGAPTPPAATP 1087
Query: 366 AGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLI 425
G +P + P T P+ G G P T
Sbjct: 1088 PSPKGGPATPSPKGAPMPPAAT-----PPSPKG---GLATPPHKGAPT------------ 1127
Query: 426 IPGADADAAVGTLVS-AAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPE 484
P A + G L + +GAP A AT P+ +G G TT A P+
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTPA----ATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
Query: 485 AEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELAT 544
P K P+ PA+ T + TT A PP P +
Sbjct: 1184 G---GLATPSPKGAPTT---PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237
Query: 545 EQKPIQDPQPTPSAPAMGAA 564
+ P P TP +P G A
Sbjct: 1238 KGAP-TTPAATPPSPKGGPA 1256
Score = 43.1 bits (100), Expect = 8e-04
Identities = 85/346 (24%), Positives = 112/346 (32%), Gaps = 60/346 (17%)
Query: 231 MTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPA--P 288
MT + A +G P+ P + A TP PSP P A+P+ AP PA P
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPKGGP-ATPSPKWAPTPPAATP 970
Query: 289 ARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKE 348
P KG P P PK PT + T PS P
Sbjct: 971 PSP-------KGGPATPSPKGAPTPP------------------AATPPSPKGGPATPSP 1005
Query: 349 ETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQ- 407
+ P P VTP G SP + P +T P+ GS P+
Sbjct: 1006 KGA------PTPPAVTPPSPKG---SPAATPFPKGA-STPPAATPPSPKGSPAATPLPKG 1055
Query: 408 --DTSLFTMQTDQSMICNLIIPGADADAAV-------GTLVSAAEGAPGEEAEAEKATVP 458
T T+ + + + GA A G + +GAP A AT P
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA----ATPP 1111
Query: 459 AGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEIT 518
+ +G G TT A P+ P K P+ PA+ T
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKG---GLATPPPKGAPTT---PAATPPSPKGGLAT 1165
Query: 519 IGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAA 564
+ TT A PP P + + P P TP +P G A
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGLA 1210
Score = 41.2 bits (95), Expect = 0.003
Identities = 80/333 (24%), Positives = 105/333 (31%), Gaps = 44/333 (13%)
Query: 246 QGAPSDSG--PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPAR-------PRSPSQ 296
+GAP+ S PL PP+E +P PS P PA+PAP + SP +
Sbjct: 862 KGAPTPSAVTPLSPKGVTLPPKE-TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
Query: 297 TR-----KGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETL 351
R KG P P PK PT P+ + T P+ P K
Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP-PSPKGGPAT 979
Query: 352 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL 411
P P TP G +P + P T + P+ GS P+ S
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAP-----TPPAVTPPSPKGSPAATPFPKGAST 1034
Query: 412 FTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIG 471
T P A L A P AT+P+ +G + G
Sbjct: 1035 PPAATP---------PSPKGSPAATPLPKGAPTTPA-------ATLPSPKGGPATPSLKG 1078
Query: 472 TETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAA 531
T A P+ P K P + PA+ T + TT A
Sbjct: 1079 APTPPAATPPSPKG---GPATPSPKGAP---MPPAATPPSPKGGLATPPHKGAPTTPAAT 1132
Query: 532 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAA 564
PP P + P P TP +P G A
Sbjct: 1133 PPSPKGGLATPPPKGAP-TTPAATPPSPKGGLA 1164
Score = 41.2 bits (95), Expect = 0.003
Identities = 87/361 (24%), Positives = 122/361 (33%), Gaps = 42/361 (11%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASP--APARPRS-PSQTRKGPPVPP 305
PS G L TPSP P+ + SP LA SP AP P + P + GP PP
Sbjct: 1203 PSPKGGLA---TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259
Query: 306 LPKVTPTKEL----QQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKP 361
PK PT + ++ P +V TP P K P P
Sbjct: 1260 -PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP-----PSPKGGPATSPPKGAPTPP 1313
Query: 362 EVT---PAGSAGV-----THSPMSQTLPWDLWTTSTDLVQPASGG------SFNGFTQPQ 407
T P GS G +P + T P T + P+S G S G T P
Sbjct: 1314 AATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 408 DTSLF---TMQTDQSMICNLIIPGADADAAVGTLVS-AAEGAPGEEAEAEKATVPAGEGV 463
T T S IP D ++ + + AP E A P+ +G
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS-KGD 1432
Query: 464 SLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP 523
A + ++ P+ + + +P+V P S E ++ + P
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT--PPSPKEPPAPKQVATSSSP 1490
Query: 524 KETTEDAAPPG-PT--SETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQE--LP 578
K+ AP G PT + P E + P AP + A A +E +P
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
Query: 579 P 579
P
Sbjct: 1551 P 1551
Score = 40.4 bits (93), Expect = 0.005
Identities = 74/357 (20%), Positives = 118/357 (33%), Gaps = 40/357 (11%)
Query: 255 LRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG-------------- 300
L + T S +P P T +P TL A P SPS G
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
Query: 301 ---PPVPPLPKVTPTKE------LQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETL 351
PV PK PT++ + +++ D+ P + V+ Q + P KK
Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP-LGVSVSPQTKRPPTKKGSAG 816
Query: 352 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFT----QPQ 407
D V+P ++ + + +S D T+ P+ G+ P+
Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876
Query: 408 DTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEE 467
+L +T + NL P + A + A + +AT PA +G+
Sbjct: 877 GVTLPPKETPTPSVVNLPFP-KEGPATPAPKQAPALSMTSSSPKKARAT-PAPKGIPASP 934
Query: 468 AKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETT 527
+ G T A P+ P K P+ PA+ T + T
Sbjct: 935 SPKGAPTPPAATPPSPKG---GPATPSPKWAPT---PPAATPPSPKGGPATPSPKGAPTP 988
Query: 528 EDAAPP----GPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPG 580
A PP GP + +P+ A + P P S A ++ A+ P G
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045
Score = 36.6 bits (83), Expect = 0.075
Identities = 77/332 (23%), Positives = 108/332 (32%), Gaps = 32/332 (9%)
Query: 245 IQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLA--PASPAPARPRSPSQTRKGPP 302
+ G S +A +P S TAS TL SP+P QT++
Sbjct: 751 VDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR--- 807
Query: 303 VPPLPKVTPTKELQQENI---ISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPF 359
PP K + + N+ +S E +F+PE S++ + P T P
Sbjct: 808 -PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 360 KPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419
VTP GVT P P + +L P G + Q S+ + ++
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTP-----SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921
Query: 420 MICNLI--IPGADADAAVGTLVSAAEGAP-GEEAEAEKATVPAGEGVSLEEAKIGTETTE 476
IP + + T +A +P G A P + K G T
Sbjct: 922 RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS 981
Query: 477 GAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPT 536
+ P A AT P K P + +G P AA P P
Sbjct: 982 PKGAPTPPA----ATPPSPKGGP-------ATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030
Query: 537 -SETPELATEQKPIQDPQPTP---SAPAMGAA 564
+ TP AT P P TP AP AA
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062
Score = 32.7 bits (73), Expect = 1.1
Identities = 70/331 (21%), Positives = 103/331 (31%), Gaps = 50/331 (15%)
Query: 240 DKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRK 299
+ +F + + S G T P PSP +PT P++ P P+ + K
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT--------PSAVTPLSPKGVTLPPK 883
Query: 300 GPPVP-----PLPKVTP-TKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLD 353
P P P PK P T +Q +S + P+ + TP+ +P +
Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS--PKKARATPAPKGIPASPSPKGA-- 939
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
P P TP G +P + W + P S P+
Sbjct: 940 ----PTPPAATPPSPKGGPATPSPK------WAPTPPAATPPSPKGGPATPSPKGAPTPP 989
Query: 414 MQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTE 473
T S G + +GAP A + P G + K G
Sbjct: 990 AATPPS-------------PKGGPATPSPKGAPTPPAVTPPS--PKGSPAATPFPK-GAS 1033
Query: 474 TTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPP 533
T A P+ A P K P+ PA+ T + T A PP
Sbjct: 1034 TPPAATPPSPKGS--PAATPLPKGAPTT---PAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 534 GPTSETPELATEQKPIQDPQPTPSAPAMGAA 564
P + + P+ P TP +P G A
Sbjct: 1089 SPKGGPATPSPKGAPM-PPAATPPSPKGGLA 1118
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 48.9 bits (115), Expect = 1e-05
Identities = 87/324 (26%), Positives = 121/324 (37%), Gaps = 37/324 (11%)
Query: 249 PSDSGPLR--IAKTPSPPEEPSP-LPSPTASPNHTLA---PASPAPARPRSPSQTRKGPP 302
P GPL + + P PP P LP P+ +P L+ P PAP+ P Q PP
Sbjct: 414 PELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPP 473
Query: 303 V-----PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFD 357
V P LP VT EL ++ ++ + + E VTT + + E
Sbjct: 474 VMAQELPGLPLVTAAVELPEQPAVTVAME--LTEQPVTTTELEQPVGMTTVE-------H 524
Query: 358 PFKPEVTPA-GSAGVTHSPMSQTLPWD-LWTTSTDLV-QPASGGSFNGFTQPQDTSLFTM 414
P PEVT A G G + M LP + TT+ +L QP+ G P T +
Sbjct: 525 PGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPELPGLPSATRALEL 584
Query: 415 QTDQSMICNLIIPGA--DADAAVGTLVSAAEGAP---GEEAEAEKATVPAGEGV-SLEEA 468
L +PG A A + S A GA G+ +P G L
Sbjct: 585 SGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQ 644
Query: 469 KIGTETTE-GAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEE-------GENEITIG 520
+ T E +S +E TV Q +PS + N + GE +T+G
Sbjct: 645 PVATVALEISVQSVVTTSELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVG 704
Query: 521 AEPKETTEDAAPPGPTSETPELAT 544
+P E T ET LA+
Sbjct: 705 VDPLMAPESHILASNTMETHILAS 728
Score = 36.2 bits (82), Expect = 0.098
Identities = 57/236 (24%), Positives = 83/236 (35%), Gaps = 38/236 (16%)
Query: 233 KLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPS-PLPSPTASPNHTLAPASPAPAR- 290
+L + A + G P+ S P + PP P LP P+A+P P P P
Sbjct: 371 ELQESSVASAMELPGPPATSMP----ELQGPPVTPVLELPGPSATP----VPELPGPLST 422
Query: 291 --PRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKE 348
P P P P P VTP +L QE P + + P + P V +
Sbjct: 423 PVPELPGPPATAVPELPGPSVTPVPQLSQE-----LPGLPAPSMGLEPPQEVPEPPVMAQ 477
Query: 349 E----TLLDLDFD-PFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGF 403
E L+ + P +P VT A +T P+ T+T+L QP +
Sbjct: 478 ELPGLPLVTAAVELPEQPAVTVA--MELTEQPV----------TTTELEQPVGMTTVEHP 525
Query: 404 TQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPA 459
P+ T+ + L +PG V T G P E +P+
Sbjct: 526 GHPEVTTATGLLGQPEATMVLELPG----QPVATTALELPGQPSVTGVPELPGLPS 577
Score = 33.1 bits (74), Expect = 0.83
Identities = 101/489 (20%), Positives = 176/489 (35%), Gaps = 52/489 (10%)
Query: 107 EDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYD---------SARH--HLEAL 155
E+ QK+ + LDT L PD+K K V D S +H H
Sbjct: 59 EEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKK 118
Query: 156 QSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAK 215
+ K++ E + + EE + K ++ N+DL+ + + + ++
Sbjct: 119 KKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAFGPSE 178
Query: 216 FHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTP--SPPEEPSPLPSP 273
++ AV+ V ++ + H + T++ A + + L + T S E S P
Sbjct: 179 TNESPAVVLEPPV-VSMEVSEPHILE--TLKPA-TKTAELSVVSTSVISEQSEQSVAVMP 234
Query: 274 TASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEIS 333
S L + AP P + + PV VT + E Q ++++ E
Sbjct: 235 EPSMTKILDSFAAAPV-PTTTLVLKSSEPV-----VTMSVEYQMKSVLKSVES------- 281
Query: 334 VTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQ 393
T+P +++ V+ P + P+ + V+ ++ P +T+ D +
Sbjct: 282 -TSPEPSKIMLVE----------PPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPE 330
Query: 394 PASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAV---GTLVSAAEGAPGEEA 450
++ + QP D + D SM +P A+ + V++A PG A
Sbjct: 331 SSAIEALRLPEQPVDVP--SEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPA 388
Query: 451 EA--EKATVPAGEGVSL--EEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPA 506
+ E P + L A E + PE AT E PSV P
Sbjct: 389 TSMPELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQ 448
Query: 507 SNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQ 566
+ E G ++G EP + E PP E P L ++ P+ AM +Q
Sbjct: 449 LSQELPGLPAPSMGLEPPQ--EVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQ 506
Query: 567 LASAREASQ 575
+ E Q
Sbjct: 507 PVTTTELEQ 515
Score = 32.3 bits (72), Expect = 1.4
Identities = 72/366 (19%), Positives = 126/366 (34%), Gaps = 15/366 (4%)
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPV 303
T+ P + P+ P P E LP+ ++ + P+ P S ++ PPV
Sbjct: 1156 TMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPV 1215
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
P+ ++ + V E +VT P PE T ++ + EV
Sbjct: 1216 SQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEV 1275
Query: 364 TPAG--SAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGF------TQPQDTSLFTMQ 415
P + V+ +P P L S V + +F+ TSL
Sbjct: 1276 VPERPVTCMVSETPAMSAEPTVL--ASEPPVMSETAETFDSMRASGHVASEVSTSLLVPA 1333
Query: 416 TDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETT 475
++ I+ A + ++ E + E+ TV V++ E + T
Sbjct: 1334 VTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVT-VP 1392
Query: 476 EGAESAQPEAEELEATVPQEKVIPSV-VIEPASNHEEEGENEITIGAEPKETTEDAAPPG 534
E A+P+ + V + PSV V+EPA + + +E+T + P
Sbjct: 1393 EPPVVAEPDYVTIPVPV-VSALEPSVPVLEPAVSVLQPSMIVSEPSVSVQESTVTVSEPA 1451
Query: 535 PT--SETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFE 592
T +T + TE P S+ + + Q L P + LH E
Sbjct: 1452 VTVSEQTQVIPTEVAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGE 1511
Query: 593 AANSDE 598
+++E
Sbjct: 1512 EPHAEE 1517
Score = 32.0 bits (71), Expect = 1.8
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 17/88 (19%)
Query: 261 PSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENI 320
P PPEEP +P L P P P P + +GP +P T L EN
Sbjct: 1148 PLPPEEPPTMPP--------LPPEEPPMTPPLPPEEPPEGPALP-----TEQSALTAENT 1194
Query: 321 ISFFEDNFVPEISVTTP----SQNEVPE 344
+ E SV+ P SQ+E+ E
Sbjct: 1195 WPTEVPSSPSEESVSQPEPPVSQSEISE 1222
Score = 30.0 bits (66), Expect = 7.0
Identities = 39/179 (21%), Positives = 71/179 (39%), Gaps = 17/179 (9%)
Query: 408 DTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEE 467
D S+ +M D+SM+ + + AD ++ + SAA+ + A+++ + +
Sbjct: 1080 DRSMMSMGADRSMMSSY----SAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDS 1135
Query: 468 AKIGTETTEGAESAQPEAEELEATVP-----QEKVIPSVVIEPASNHEEEGENEITIGAE 522
T+T A P E T+P + + P + E + + AE
Sbjct: 1136 Y---TDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAE 1192
Query: 523 PKETTEDAAPPGPTSET---PELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELP 578
TE P P+ E+ PE Q I +P P+ ++ A+D EA+ +P
Sbjct: 1193 NTWPTE--VPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVP 1249
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 48.9 bits (115), Expect = 1e-05
Identities = 87/324 (26%), Positives = 121/324 (37%), Gaps = 37/324 (11%)
Query: 249 PSDSGPLR--IAKTPSPPEEPSP-LPSPTASPNHTLA---PASPAPARPRSPSQTRKGPP 302
P GPL + + P PP P LP P+ +P L+ P PAP+ P Q PP
Sbjct: 414 PELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPP 473
Query: 303 V-----PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFD 357
V P LP VT EL ++ ++ + + E VTT + + E
Sbjct: 474 VMAQELPGLPLVTAAVELPEQPAVTVAME--LTEQPVTTTELEQPVGMTTVE-------H 524
Query: 358 PFKPEVTPA-GSAGVTHSPMSQTLPWD-LWTTSTDLV-QPASGGSFNGFTQPQDTSLFTM 414
P PEVT A G G + M LP + TT+ +L QP+ G P T +
Sbjct: 525 PGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPELPGLPSATRALEL 584
Query: 415 QTDQSMICNLIIPGA--DADAAVGTLVSAAEGAP---GEEAEAEKATVPAGEGV-SLEEA 468
L +PG A A + S A GA G+ +P G L
Sbjct: 585 SGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQ 644
Query: 469 KIGTETTE-GAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEE-------GENEITIG 520
+ T E +S +E TV Q +PS + N + GE +T+G
Sbjct: 645 PVATVALEISVQSVVTTSELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVG 704
Query: 521 AEPKETTEDAAPPGPTSETPELAT 544
+P E T ET LA+
Sbjct: 705 VDPLMAPESHILASNTMETHILAS 728
Score = 36.2 bits (82), Expect = 0.098
Identities = 57/236 (24%), Positives = 83/236 (35%), Gaps = 38/236 (16%)
Query: 233 KLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPS-PLPSPTASPNHTLAPASPAPAR- 290
+L + A + G P+ S P + PP P LP P+A+P P P P
Sbjct: 371 ELQESSVASAMELPGPPATSMP----ELQGPPVTPVLELPGPSATP----VPELPGPLST 422
Query: 291 --PRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKE 348
P P P P P VTP +L QE P + + P + P V +
Sbjct: 423 PVPELPGPPATAVPELPGPSVTPVPQLSQE-----LPGLPAPSMGLEPPQEVPEPPVMAQ 477
Query: 349 E----TLLDLDFD-PFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGF 403
E L+ + P +P VT A +T P+ T+T+L QP +
Sbjct: 478 ELPGLPLVTAAVELPEQPAVTVA--MELTEQPV----------TTTELEQPVGMTTVEHP 525
Query: 404 TQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPA 459
P+ T+ + L +PG V T G P E +P+
Sbjct: 526 GHPEVTTATGLLGQPEATMVLELPG----QPVATTALELPGQPSVTGVPELPGLPS 577
Score = 33.1 bits (74), Expect = 0.83
Identities = 101/489 (20%), Positives = 176/489 (35%), Gaps = 52/489 (10%)
Query: 107 EDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYD---------SARH--HLEAL 155
E+ QK+ + LDT L PD+K K V D S +H H
Sbjct: 59 EEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKK 118
Query: 156 QSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAK 215
+ K++ E + + EE + K ++ N+DL+ + + + ++
Sbjct: 119 KKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAFGPSE 178
Query: 216 FHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTP--SPPEEPSPLPSP 273
++ AV+ V ++ + H + T++ A + + L + T S E S P
Sbjct: 179 TNESPAVVLEPPV-VSMEVSEPHILE--TLKPA-TKTAELSVVSTSVISEQSEQSVAVMP 234
Query: 274 TASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEIS 333
S L + AP P + + PV VT + E Q ++++ E
Sbjct: 235 EPSMTKILDSFAAAPV-PTTTLVLKSSEPV-----VTMSVEYQMKSVLKSVES------- 281
Query: 334 VTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQ 393
T+P +++ V+ P + P+ + V+ ++ P +T+ D +
Sbjct: 282 -TSPEPSKIMLVE----------PPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPE 330
Query: 394 PASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAV---GTLVSAAEGAPGEEA 450
++ + QP D + D SM +P A+ + V++A PG A
Sbjct: 331 SSAIEALRLPEQPVDVP--SEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPA 388
Query: 451 EA--EKATVPAGEGVSL--EEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPA 506
+ E P + L A E + PE AT E PSV P
Sbjct: 389 TSMPELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQ 448
Query: 507 SNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQ 566
+ E G ++G EP + E PP E P L ++ P+ AM +Q
Sbjct: 449 LSQELPGLPAPSMGLEPPQ--EVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQ 506
Query: 567 LASAREASQ 575
+ E Q
Sbjct: 507 PVTTTELEQ 515
Score = 32.3 bits (72), Expect = 1.4
Identities = 72/366 (19%), Positives = 126/366 (34%), Gaps = 15/366 (4%)
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPV 303
T+ P + P+ P P E LP+ ++ + P+ P S ++ PPV
Sbjct: 1156 TMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPV 1215
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
P+ ++ + V E +VT P PE T ++ + EV
Sbjct: 1216 SQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEV 1275
Query: 364 TPAG--SAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGF------TQPQDTSLFTMQ 415
P + V+ +P P L S V + +F+ TSL
Sbjct: 1276 VPERPVTCMVSETPAMSAEPTVL--ASEPPVMSETAETFDSMRASGHVASEVSTSLLVPA 1333
Query: 416 TDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETT 475
++ I+ A + ++ E + E+ TV V++ E + T
Sbjct: 1334 VTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVT-VP 1392
Query: 476 EGAESAQPEAEELEATVPQEKVIPSV-VIEPASNHEEEGENEITIGAEPKETTEDAAPPG 534
E A+P+ + V + PSV V+EPA + + +E+T + P
Sbjct: 1393 EPPVVAEPDYVTIPVPV-VSALEPSVPVLEPAVSVLQPSMIVSEPSVSVQESTVTVSEPA 1451
Query: 535 PT--SETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFE 592
T +T + TE P S+ + + Q L P + LH E
Sbjct: 1452 VTVSEQTQVIPTEVAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGE 1511
Query: 593 AANSDE 598
+++E
Sbjct: 1512 EPHAEE 1517
Score = 32.0 bits (71), Expect = 1.8
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 17/88 (19%)
Query: 261 PSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENI 320
P PPEEP +P L P P P P + +GP +P T L EN
Sbjct: 1148 PLPPEEPPTMPP--------LPPEEPPMTPPLPPEEPPEGPALP-----TEQSALTAENT 1194
Query: 321 ISFFEDNFVPEISVTTP----SQNEVPE 344
+ E SV+ P SQ+E+ E
Sbjct: 1195 WPTEVPSSPSEESVSQPEPPVSQSEISE 1222
Score = 30.0 bits (66), Expect = 7.0
Identities = 39/179 (21%), Positives = 71/179 (39%), Gaps = 17/179 (9%)
Query: 408 DTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEE 467
D S+ +M D+SM+ + + AD ++ + SAA+ + A+++ + +
Sbjct: 1080 DRSMMSMGADRSMMSSY----SAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDS 1135
Query: 468 AKIGTETTEGAESAQPEAEELEATVP-----QEKVIPSVVIEPASNHEEEGENEITIGAE 522
T+T A P E T+P + + P + E + + AE
Sbjct: 1136 Y---TDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAE 1192
Query: 523 PKETTEDAAPPGPTSET---PELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELP 578
TE P P+ E+ PE Q I +P P+ ++ A+D EA+ +P
Sbjct: 1193 NTWPTE--VPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVP 1249
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 48.5 bits (114), Expect = 2e-05
Identities = 73/314 (23%), Positives = 113/314 (35%), Gaps = 44/314 (14%)
Query: 261 PSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENI 320
P+PP PS S ++SP+ + + +SP+P P P PP PP P+
Sbjct: 184 PAPPPAPS---SASSSPSPSPSSSSPSPPPPPPP----PAPPAPPAPRFD---------- 226
Query: 321 ISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTL 380
D F P +P PE K +DPF+P + S+ T SP +
Sbjct: 227 ---IYDPFHPTDEAYSPP--PAPEQK---------YDPFEPTGSNPSSSAGTPSPEEEEE 272
Query: 381 PWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVS 440
+ + + G S ++ +T L + D S+ + + A T +
Sbjct: 273 EEEEEEEEEEDEEEEEGLS-QSISRISET-LAGIYDDNSLSQDFPGDESPRPDAQPTQPT 330
Query: 441 AAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPS 500
A G P + ++ +A V + +GTE AE+ + +E +P
Sbjct: 331 PAPGTP-PQVDSTRADGAMRRRVFV----VGTE----AEACREGKVSVEVVTAGGAALPP 381
Query: 501 VVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPA 560
++ P + EEG EI E PG + P A P P P P AP
Sbjct: 382 PLLPPGDSEIEEG--EIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPR 439
Query: 561 MGAADQLASAREAS 574
D S S
Sbjct: 440 APEGDDFLSLHAES 453
Score = 30.4 bits (67), Expect = 5.4
Identities = 36/146 (24%), Positives = 46/146 (31%), Gaps = 12/146 (8%)
Query: 434 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVP 493
A GT + GEE A+ + P + A T + PE L
Sbjct: 953 AAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEAT 1012
Query: 494 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQ 553
+E + E EEE E E E+ P T+ T A P P
Sbjct: 1013 EEAGVRGGAEEEEEEEEEEEEEE----------EEEEQQPATTTATSTAAA--APSTAPS 1060
Query: 554 PTPSAPAMGAADQLASAREASQELPP 579
+A GA D AS LPP
Sbjct: 1061 AGSTAGDSGAEDGPASRVSQLPTLPP 1086
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 48.5 bits (114), Expect = 2e-05
Identities = 53/162 (32%), Positives = 67/162 (41%), Gaps = 21/162 (12%)
Query: 250 SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTL--APASPAPARPR--SPSQTR------K 299
SDSG K P+P P L +S N T AP P PR SQ + +
Sbjct: 129 SDSGK----KVPTPAPRPLLLKKSVSSENPTYPSAPLKPVTVPPRLAGASQAKAYKSLGE 184
Query: 300 GPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPF 359
GPP P V +K L ++IS F+D+ +P TPS N E E +L L DP
Sbjct: 185 GPPANPPVPVLQSKPLVDIDLIS-FDDDVLP-----TPSGNLAEESVGSEMVLGLHEDPQ 238
Query: 360 KPEVTPAGS-AGVTHSPMSQTLPWDLWTTSTDLVQPASGGSF 400
P PA G T S +S L T + + P G F
Sbjct: 239 SPPPLPAEKPIGNTFSTVSGKLSNVERTRNLESNHPGQTGGF 280
Score = 35.4 bits (80), Expect = 0.17
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 25/110 (22%)
Query: 547 KPIQDPQPTPSAPAMGAADQLASAREAS------QELPPGFLYKVETLHDFEAANSDELT 600
+P++D PT A + L + +E S LP + E LH F A SD+L+
Sbjct: 567 EPVED-YPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWC---EALHSFTAETSDDLS 622
Query: 601 LQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTR 650
+RGD + ++ +SDW + R L +G+FP F R
Sbjct: 623 FKRGDRIQILER--------------LDSDWCRGR-LQDREGIFPAVFVR 657
Score = 35.4 bits (80), Expect = 0.17
Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 17/94 (18%)
Query: 559 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ 618
PA+ A A+ +P G K + L+DF N DEL+ + GD++ + S
Sbjct: 652 PAVFVRPCPAEAKSMLAIVPKG--RKAKALYDFRGENEDELSFKAGDIITELES-----V 704
Query: 619 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652
D W+ G +L G+FP+N+ + L
Sbjct: 705 DDDWMSG----------ELMGKSGIFPKNYIQFL 728
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,308,137
Number of Sequences: 37866
Number of extensions: 1671186
Number of successful extensions: 24664
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 345
Number of HSP's successfully gapped in prelim test: 1186
Number of HSP's that attempted gapping in prelim test: 13468
Number of HSP's gapped (non-prelim): 8419
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.