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Search of human proteins with 21361241
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
(983 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 2011 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 1410 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 1398 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 1290 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 1286 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 1285 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 1169 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 1126 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 1124 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 1115 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 1109 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 1102 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 972 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 924 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 923 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 772 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 763 0.0
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 554 e-157
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 324 2e-88
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 231 2e-60
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 228 2e-59
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 223 7e-58
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 223 9e-58
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... 223 9e-58
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 222 1e-57
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 222 2e-57
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 222 2e-57
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 221 3e-57
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi... 221 3e-57
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens] 221 3e-57
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 2011 bits (5211), Expect = 0.0
Identities = 983/983 (100%), Positives = 983/983 (100%)
Query: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE
Sbjct: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
Query: 61 HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF 120
HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF
Sbjct: 61 HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF 120
Query: 121 NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY
Sbjct: 121 NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Query: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP 240
LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP
Sbjct: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP 240
Query: 241 RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG 300
RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG
Sbjct: 241 RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG 300
Query: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN 360
SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN
Sbjct: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN 360
Query: 361 IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS 420
IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS
Sbjct: 361 IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS 420
Query: 421 PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ 480
PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ
Sbjct: 421 PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ 480
Query: 481 ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESS 540
ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESS
Sbjct: 481 ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESS 540
Query: 541 QVVMIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPH 600
QVVMIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPH
Sbjct: 541 QVVMIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPH 600
Query: 601 TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT 660
TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT
Sbjct: 601 TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT 660
Query: 661 EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV 720
EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV
Sbjct: 661 EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV 720
Query: 721 IQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYT 780
IQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYT
Sbjct: 721 IQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYT 780
Query: 781 TRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEG 840
TRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEG
Sbjct: 781 TRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEG 840
Query: 841 YRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSN 900
YRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSN
Sbjct: 841 YRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSN 900
Query: 901 LLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVG 960
LLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVG
Sbjct: 901 LLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVG 960
Query: 961 PQKKIISSIKALETQSKNGPVPV 983
PQKKIISSIKALETQSKNGPVPV
Sbjct: 961 PQKKIISSIKALETQSKNGPVPV 983
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 1410 bits (3650), Expect = 0.0
Identities = 668/977 (68%), Positives = 819/977 (83%), Gaps = 8/977 (0%)
Query: 10 LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69
LL C+ L + L+ PSNEVNLLDS+T+ G+LGWI++P +GWEEI VDE+Y PI TYQ
Sbjct: 44 LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
Query: 70 VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129
VC VM+ +QNNWL T+W+ A +I++ELKFTLRDCNS+P LGTCKETFN+YY ESDD
Sbjct: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
Query: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189
+G +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
Query: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248
+ALVSVRVY+KKCP V++LA+FPDT+ DS L+EV GSCVN+S ++PP+M+CS EG
Sbjct: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
Query: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308
EWLVPIGKC C AGYEE+ CQ CRPGF+KA C KCPPHS T E+ S +C CE
Sbjct: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
Query: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368
+YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W P DTGGRKDV++ I CKKC
Sbjct: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
Query: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428
+ CE C +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS RQ+ +V
Sbjct: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
Query: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488
++TTNQAAPSPV +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
Query: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAIS 548
++ T +T LKP ++YVFQIRARTAAGYG SR+FEFET+P F+ S + SQ+ +IA+S
Sbjct: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP-VFAASSDQSQIPVIAVS 578
Query: 549 AAVAIILLTVVIYVLI-GRFCGY-KSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPT 606
V +ILL VVI VL+ GR CGY K+K +E+++HF NGH+KLPG+RTY+DPHTYEDP
Sbjct: 579 VTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 638
Query: 607 QAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRD 666
QAVHEFAKE++A+ I+I++V+GAGEFGEVCSGRLKLP K+E+ VAIKTLKVGYTEKQRRD
Sbjct: 639 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 698
Query: 667 FLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGM 726
FLGEASIMGQFDHPNII LEGVVTKSKPVMIVTEYMENGSLD+FL+K+D QFTVIQLVGM
Sbjct: 699 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 758
Query: 727 LRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 786
LRGI++GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
Sbjct: 759 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 818
Query: 787 PIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPP 846
PIRWT+PEAIA+RKFTSASDVWSYGIV+WEV+SYGERPYWEM+NQDVIKAV+EGYRLP P
Sbjct: 819 PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 878
Query: 847 MDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQS 906
MDCPAALYQLMLDCWQK+RN+RPKF++IV++LDKLIRNP SLK + +A+ R SNLL + S
Sbjct: 879 MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 938
Query: 907 NVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKII 966
+ +R+ G+WL + EIF YSS D +A+++ +D++++GVT+VG QKKI+
Sbjct: 939 PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 998
Query: 967 SSIKALETQSKNGPVPV 983
+S++ ++ Q NG VP+
Sbjct: 999 NSLQEMKVQLVNGMVPL 1015
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 1398 bits (3618), Expect = 0.0
Identities = 668/999 (66%), Positives = 819/999 (81%), Gaps = 30/999 (3%)
Query: 10 LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69
LL C+ L + L+ PSNEVNLLDS+T+ G+LGWI++P +GWEEI VDE+Y PI TYQ
Sbjct: 44 LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
Query: 70 VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129
VC VM+ +QNNWL T+W+ A +I++ELKFTLRDCNS+P LGTCKETFN+YY ESDD
Sbjct: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
Query: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189
+G +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
Query: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248
+ALVSVRVY+KKCP V++LA+FPDT+ DS L+EV GSCVN+S ++PP+M+CS EG
Sbjct: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
Query: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308
EWLVPIGKC C AGYEE+ CQ CRPGF+KA C KCPPHS T E+ S +C CE
Sbjct: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
Query: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368
+YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W P DTGGRKDV++ I CKKC
Sbjct: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
Query: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428
+ CE C +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS RQ+ +V
Sbjct: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
Query: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488
++TTNQAAPSPV +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
Query: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAIS 548
++ T +T LKP ++YVFQIRARTAAGYG SR+FEFET+P F+ S + SQ+ +IA+S
Sbjct: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP-VFAASSDQSQIPVIAVS 578
Query: 549 AAVAIILLTVVIYVLI---------GRF--------------CGY-KSKHGADEKRLHFG 584
V +ILL VVI VL+ GR CGY K+K +E+++HF
Sbjct: 579 VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH 638
Query: 585 NGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPS 644
NGH+KLPG+RTY+DPHTYEDP QAVHEFAKE++A+ I+I++V+GAGEFGEVCSGRLKLP
Sbjct: 639 NGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG 698
Query: 645 KKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMEN 704
K+E+ VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNII LEGVVTKSKPVMIVTEYMEN
Sbjct: 699 KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMEN 758
Query: 705 GSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSD 764
GSLD+FL+K+D QFTVIQLVGMLRGI++GMKYLSDMGYVHRDLAARNILINSNLVCKVSD
Sbjct: 759 GSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSD 818
Query: 765 FGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERP 824
FGLSRVLEDDPEAAYTTRGGKIPIRWT+PEAIA+RKFTSASDVWSYGIV+WEV+SYGERP
Sbjct: 819 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERP 878
Query: 825 YWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRN 884
YWEM+NQDVIKAV+EGYRLP PMDCPAALYQLMLDCWQK+RN+RPKF++IV++LDKLIRN
Sbjct: 879 YWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRN 938
Query: 885 PGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIA 944
P SLK + +A+ R SNLL + S + +R+ G+WL + EIF YSS D +A
Sbjct: 939 PSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVA 998
Query: 945 KISTDDMKKVGVTVVGPQKKIISSIKALETQSKNGPVPV 983
+++ +D++++GVT+VG QKKI++S++ ++ Q NG VP+
Sbjct: 999 QVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL 1037
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 1290 bits (3339), Expect = 0.0
Identities = 621/996 (62%), Positives = 771/996 (77%), Gaps = 55/996 (5%)
Query: 27 SNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNW 86
+N+V LLD+ T+ GELGW +YP +GW+ I+ +DEH PI TYQVCNVM+ +QNNWLRTNW
Sbjct: 126 NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185
Query: 87 VPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTI 146
+ R++AQKIYVE+KFTLRDCNSIP VLGTCKETFNL+YMESD+ HG+KF+ +Q+TKIDTI
Sbjct: 186 ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245
Query: 147 AADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTV 206
AADESFTQMDLGDRILKLNTEIREVGP+ +KGFYLAFQD+GAC+ALVSVRV++KKCPFTV
Sbjct: 246 AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305
Query: 207 KNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEE 265
+NLAMFPDT+P +DS SLVEVRGSCV +++E D P++YC +G+WLVP+G+C C+ GYEE
Sbjct: 306 RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365
Query: 266 RGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRP 325
C ACRPGFYKA GN KC+KCPPHS T + + C+CE YFRA+KDPPSMACTRP
Sbjct: 366 IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
PS+PRNV+ NINET++IL+WS P DTGGRKD+T+++ICKKCG + QCE C +RF+PR
Sbjct: 426 PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKK 445
GL N +V V D ++H NYTFEI+A+NGVSELS P+ F A+++TT+Q APS + ++K
Sbjct: 486 HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
Query: 446 DRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIY 505
D S+NSI+LSWQ P NG ILDYE+KYYEK+ ++ +Y+ R++ +V I+ LKP T Y
Sbjct: 546 DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
Query: 506 VFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTV--VIYVL 563
VF IR RTA GY S+KFEFET ++ ++ E Q+++IA +A LL + + +++
Sbjct: 606 VFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLI 665
Query: 564 IGRFCGY-KSKHGADEKRL-HFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNI 621
GR Y K+K ++EKR H NGHL+ PG++TY+DP TYEDP+ AVHEFAKE+D + I
Sbjct: 666 TGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRI 725
Query: 622 SIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 681
I++V+GAGEFGEVCSGRLK P K+EI VAIKTLK G+ ++QRRDFL EASIMGQFDHPN
Sbjct: 726 RIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPN 785
Query: 682 IIRLEGVVTK------------------------------------------SKPVMIVT 699
IIRLEGVVTK +PVMIV
Sbjct: 786 IIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVV 845
Query: 700 EYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLV 759
EYMENGSLDSFLRKHD FTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNIL+NSNLV
Sbjct: 846 EYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLV 905
Query: 760 CKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMS 819
CKVSDFGLSRVLEDDPEAAYTT GGKIPIRWT+PEAIAYRKF+SASD WSYGIV+WEVMS
Sbjct: 906 CKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMS 965
Query: 820 YGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879
YGERPYWEMSNQDVI +++EGYRLP PM CPA+L+QLML CWQK+RN+RPKF IVS LD
Sbjct: 966 YGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLD 1025
Query: 880 KLIRNPGSLKIITSAAARPSNLLLDQSNVDI---TTFRTTGDWLNGVWTAHCKEIFTGVE 936
KLIRNP +L + L++ +S ++ F T GDWL+ + K F
Sbjct: 1026 KLIRNPSALHTLVE-----DILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG 1080
Query: 937 YSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKAL 972
+++ D I+++S DD++++GV ++G Q++I+SSI+ L
Sbjct: 1081 FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTL 1116
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 1286 bits (3329), Expect = 0.0
Identities = 609/963 (63%), Positives = 769/963 (79%), Gaps = 15/963 (1%)
Query: 25 QPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRT 84
Q + EV LLDSK Q EL WIS P +GWEEISG+DE+YTPIRTYQVC VM+ +QNNWLRT
Sbjct: 28 QAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRT 87
Query: 85 NWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKID 144
NW+ + +AQ+I+VELKFTLRDCNS+P VLGTCKETFNLYY E+D D G RE+ + KID
Sbjct: 88 NWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKID 147
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESFTQ DLG+R +KLNTE+RE+GP++KKGFYLAFQDVGAC+ALVSV+VY+KKC
Sbjct: 148 TIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWS 207
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEE--DPPRMYCSTEGEWLVPIGKCSCNA 261
++NLA+FPDTV + SLVEVRG+CV++++EE + PRM+CS EGEWLVPIGKC C A
Sbjct: 208 IIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKA 267
Query: 262 GYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMA 321
GY+++G C+ C GFYK+ +++C++CP HS + ++GS C CE+ Y+RA DPP +A
Sbjct: 268 GYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVA 327
Query: 322 CTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
CTRPPS+P+N+I NIN+T+V L+WS P D GGR DVT+ I+CK+C W +C PC N+
Sbjct: 328 CTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIG 387
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
++P+Q GL + VTV DLLAH NYTFE++AVNGVS+LS R FAAVSITT QAAPS V
Sbjct: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
+ K+R + S+ LSWQEPEHPNG+I +YE+KYYEK ++E +Y+ ++ + T+ +I++LKP
Sbjct: 448 GVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKP 507
Query: 502 DTIYVFQIRARTAAGYGTNSRKFEFETSPDSF-------SISGESSQVVMIAISAAVAII 554
T+YVFQIRA TAAGYG S + + T ++ ++S E + V++IA+ A I
Sbjct: 508 GTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTI 567
Query: 555 LLTVVIY-VLIGR-FCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEF 612
+L +++ +IGR CGY ++ L+F H K PG +TY+DP TYEDP +AVH+F
Sbjct: 568 ILVFMVFGFIIGRRHCGYSKADQEGDEELYF---HFKFPGTKTYIDPETYEDPNRAVHQF 624
Query: 613 AKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEAS 672
AKELDA+ I I++V+GAGEFGEVCSGRLKLP K++++VAIKTLKVGYTEKQRRDFL EAS
Sbjct: 625 AKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEAS 684
Query: 673 IMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIAS 732
IMGQFDHPN++ LEGVVT+ KPVMIV E+MENG+LD+FLRKHD QFTVIQLVGMLRGIA+
Sbjct: 685 IMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAA 744
Query: 733 GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTS 792
GM+YL+DMGYVHRDLAARNIL+NSNLVCKVSDFGLSRV+EDDPEA YTT GGKIP+RWT+
Sbjct: 745 GMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 804
Query: 793 PEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAA 852
PEAI YRKFTSASDVWSYGIV+WEVMSYGERPYW+MSNQDVIKA++EGYRLP PMDCPA
Sbjct: 805 PEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAG 864
Query: 853 LYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITT 912
L+QLMLDCWQK+R RPKFEQIV ILDK+IRNP SLK +RP + LLDQ+ D TT
Sbjct: 865 LHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTT 924
Query: 913 FRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKAL 972
F + G+WL + K+ FT Y+S +++A+++ +D+ +G+T+VG QKKI+SSI+ +
Sbjct: 925 FCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTM 984
Query: 973 ETQ 975
Q
Sbjct: 985 RAQ 987
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 1285 bits (3325), Expect = 0.0
Identities = 615/956 (64%), Positives = 763/956 (79%), Gaps = 13/956 (1%)
Query: 26 PSNEVNLLDSKTIQGELGWISYPSHG-WEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRT 84
P+NEV LLDS+++QGELGWI+ P G WEE+S +DE TPIRTYQVCNVM+ SQNNWLRT
Sbjct: 27 PANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRT 86
Query: 85 NWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKID 144
+W+ R AQ++Y+E+KFTLRDCNS+P V+GTCKETFNLYY ESD+D RE+QF KID
Sbjct: 87 DWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKID 146
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESFTQ+D+GDRI+KLNTEIR+VGP++KKGFYLAFQDVGAC+ALVSVRV++KKCP
Sbjct: 147 TIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPL 206
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGY 263
TV+NLA FPDT+ D+ SLVEVRGSCVNNS+E+D P+MYC +GEWLVPIG C CNAG+
Sbjct: 207 TVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGH 266
Query: 264 EERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACT 323
EER CQAC+ G+YKAL + CAKCPPHS + +G+ +C C+ +FRAD D SM CT
Sbjct: 267 EERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCT 326
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG-WNIKQCEPCSPNVRF 382
RPPS+P N+ISN+NETSV L+WS P +TGGR+D+++N++CKKCG + +C PC V +
Sbjct: 327 RPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHY 386
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
P+Q GL T V++TDLLAHTNYTFEI AVNGVS+ + P Q +V++TTNQAAPS +
Sbjct: 387 TPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIAL 446
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
++ +R S++L+W EP+ PNG+IL+YEVKYYEK + E SY I+R N I L P
Sbjct: 447 VQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPL 506
Query: 503 TIYVFQIRARTAAGYGTNSRKFEFETS--PDSFSISGESSQVVMIAISAAVAIILLTVVI 560
T YVF +RARTAAGYG S E T+ P G +S V+++++S +V ++++ +
Sbjct: 507 TSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAA 566
Query: 561 YVLIGRFCGY-KSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDAT 619
+V+ R Y K+K ADE++ HL G+RTYVDP TYEDP QAV EFAKE+DA+
Sbjct: 567 FVISRRRSKYSKAKQEADEEK------HLN-QGVRTYVDPFTYEDPNQAVREFAKEIDAS 619
Query: 620 NISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679
I I+KV+G GEFGEVCSGRLK+P K+EI VAIKTLK GYT+KQRRDFL EASIMGQFDH
Sbjct: 620 CIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDH 679
Query: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSD 739
PNII LEGVVTK KPVMI+TEYMENGSLD+FLRK+D +FTVIQLVGMLRGI SGMKYLSD
Sbjct: 680 PNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSD 739
Query: 740 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYR 799
M YVHRDLAARNIL+NSNLVCKVSDFG+SRVLEDDPEAAYTTRGGKIPIRWT+PEAIAYR
Sbjct: 740 MSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYR 799
Query: 800 KFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLD 859
KFTSASDVWSYGIV+WEVMSYGERPYW+MSNQDVIKA++EGYRLPPPMDCP AL+QLMLD
Sbjct: 800 KFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLD 859
Query: 860 CWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDW 919
CWQK+R++RPKF QIV++LDKLIRNP SLK + ++RP+ LLD S+ + + + GDW
Sbjct: 860 CWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDW 919
Query: 920 LNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQ 975
L + K+ FT Y++ + + ++ +D+ ++G+T + Q KI+SS++A+ TQ
Sbjct: 920 LQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQ 975
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
Length = 1005
Score = 1169 bits (3024), Expect = 0.0
Identities = 558/975 (57%), Positives = 730/975 (74%), Gaps = 27/975 (2%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
EVNLLD+ TI G+ GW++YP+HGW+ I+ VDE + PI TYQVCNVM +QNNWLRT+WVP
Sbjct: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAA 148
R+ A+++Y E+KFTLRDCNS+P VLGTCKETFNLYY+ESD D G +E QF KIDTIAA
Sbjct: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAA 150
Query: 149 DESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKN 208
DESFT DLG R LKLNTE+R VGP++K+GFYLAFQD+GAC+A++S+R+Y+KKCP V+N
Sbjct: 151 DESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRN 210
Query: 209 LAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERG 267
LA F + V DS SLVEVRG CV +S+E D P+MYCS EGEWLVPIGKC C+AGYEER
Sbjct: 211 LAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERR 270
Query: 268 FMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPS 327
C AC GFYK+ G+ CA+CPPHS + + C C+ +Y+RA DPPS ACTRPPS
Sbjct: 271 DACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPS 330
Query: 328 SPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
+P N+IS++N TSV L+W+ PLD GGR D+T+N +C++C W + +CE C RF+P+Q
Sbjct: 331 APVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQT 390
Query: 388 GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
L ++ V +LLAH NY+F I+AVNGVS+LS PR+ A V+ITTNQAAPS V+ I+++R
Sbjct: 391 SLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQER 450
Query: 448 TSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVF 507
+ S+SL WQEPE PNGIIL+YE+KYYEK ++ SY+ L+A T T+S LKP T YVF
Sbjct: 451 AGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVF 510
Query: 508 QIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVLIGRF 567
Q+RART+AG G S+ E ET ++ +V I ++ +++L +++ + R
Sbjct: 511 QVRARTSAGCGRFSQAMEVETGKPRPRY--DTRTIVWICLTLITGLVVLLLLL-ICKKRH 567
Query: 568 CGY-KSKHGADEKRLHFGNGHL-------------KLPGLRTYVDPHTYEDPTQAVHEFA 613
CGY K+ +DE+++H+ NG KLP + Y +PHTYE+P +A F
Sbjct: 568 CGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFT 627
Query: 614 KELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASI 673
+E++A+ I I+K++G+G+ GEVC GRL++P ++++ VAIK LK GYTE+QRRDFL EASI
Sbjct: 628 REIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASI 687
Query: 674 MGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASG 733
MGQFDHPNIIRLEGVVT+ + MIVTEYMENGSLD+FLR HD QFT++QLVGMLRG+ +G
Sbjct: 688 MGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAG 747
Query: 734 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSP 793
M+YLSD+GYVHRDLAARN+L++SNLVCKVSDFGLSRVLEDDP+AAYTT GGKIPIRWT+P
Sbjct: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
Query: 794 EAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAAL 853
EAIA+R F+SASDVWS+G+V+WEV++YGERPYW M+N+DVI +V+EGYRLP PM CP AL
Sbjct: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
Query: 854 YQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTF 913
+QLMLDCW KDR RP+F QIVS+LD LIR+P SL+ + + P + +S D+
Sbjct: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFV-RSCFDLRGG 926
Query: 914 R------TTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIIS 967
T GDWL+ + ++ F YSS + +++ D++ +G+T++G QKKI+
Sbjct: 927 SGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILG 986
Query: 968 SIKALETQ--SKNGP 980
SI+ + Q S GP
Sbjct: 987 SIQTMRAQLTSTQGP 1001
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 1126 bits (2913), Expect = 0.0
Identities = 550/962 (57%), Positives = 719/962 (74%), Gaps = 19/962 (1%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
E L+DS T ELGW+ +P GWEE+SG DE+ IRTYQVCNV + SQNNWLRT ++
Sbjct: 20 EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
R A +I+VE+KF++RDC+SIP V G+CKETFNLYY E+D D K + E+ + K+D
Sbjct: 80 RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESF+Q+DLG R++K+NTE+R GPV++ GFYLAFQD G C++L++VRV+++KCP
Sbjct: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
++N A+F +T+ +S SLV RGSC+ N++E D P ++YC+ +GEWLVPIG+C C AG
Sbjct: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
Query: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320
+E E G +C+ C G +KA G+ C CP +S T +G+ NC C N Y+RAD DP M
Sbjct: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
CT PS+P+ VIS++NETS++L+W+ P D+GGR+D+ +NIICK CG C C NV
Sbjct: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
++ PRQ GLT + ++DLLAHT YTFEI AVNGV++ S QFA+V+ITTNQAAPS V
Sbjct: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ + + +SI+LSW +P+ PNG+ILDYE++YYEK+ E + T +++ VT+ LK
Sbjct: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
Query: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDS-FSISGESSQVVMIAISAAVAIILLTVV 559
IYVFQ+RART AGYG S K F+T ++ + S + ++I SAA + L+ VV
Sbjct: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVV 559
Query: 560 IYVLIGRFCGYKSKHGAD----EKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKE 615
+ ++ C + AD +K H+ +GH+ PG++ Y+DP TYEDP +AV EFAKE
Sbjct: 560 VIAIV---CNRRGFERADSEYTDKLQHYTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKE 615
Query: 616 LDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMG 675
+D + + I++V+GAGEFGEVCSG LKLP K+EI VAIKTLK GYTEKQRRDFL EASIMG
Sbjct: 616 IDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG 675
Query: 676 QFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMK 735
QFDHPN+I LEGVVTKS PVMI+TE+MENGSLDSFLR++D QFTVIQLVGMLRGIA+GMK
Sbjct: 676 QFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMK 735
Query: 736 YLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTSP 793
YL+DM YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDD + YT+ GGKIPIRWT+P
Sbjct: 736 YLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAP 795
Query: 794 EAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAAL 853
EAI YRKFTSASDVWSYGIV+WEVMSYGERPYW+M+NQDVI A+++ YRLPPPMDCP+AL
Sbjct: 796 EAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSAL 855
Query: 854 YQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTF 913
+QLMLDCWQKDRN+RPKF QIV+ LDK+IRNP SLK + ++ + LLD++ D T+F
Sbjct: 856 HQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSF 915
Query: 914 RTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALE 973
T +WL + KE F ++S D ++++ +D+ +VGVT+ G QKKI++SI+ +
Sbjct: 916 NTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMR 975
Query: 974 TQ 975
Q
Sbjct: 976 AQ 977
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 1124 bits (2908), Expect = 0.0
Identities = 549/960 (57%), Positives = 719/960 (74%), Gaps = 14/960 (1%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
E L+DS T ELGW+ +P GWEE+SG DE+ IRTYQVCNV + SQNNWLRT ++
Sbjct: 20 EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
R A +I+VE+KF++RDC+SIP V G+CKETFNLYY E+D D K + E+ + K+D
Sbjct: 80 RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESF+Q+DLG R++K+NTE+R GPV++ GFYLAFQD G C++L++VRV+++KCP
Sbjct: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
++N A+F +T+ +S SLV RGSC+ N++E D P ++YC+ +GEWLVPIG+C C AG
Sbjct: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
Query: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320
+E E G +C+ C G +KA G+ C CP +S T +G+ NC C N Y+RAD DP M
Sbjct: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
CT PS+P+ VIS++NETS++L+W+ P D+GGR+D+ +NIICK CG C C NV
Sbjct: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
++ PRQ GLT + ++DLLAHT YTFEI AVNGV++ S QFA+V+ITTNQAAPS V
Sbjct: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ + + +SI+LSW +P+ PNG+ILDYE++YYEK+ E + T +++ VT+ LK
Sbjct: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
Query: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDS-FSISGESSQVVMIAISAAVAIILLTVV 559
IYVFQ+RART AGYG S K F+T ++ + S + ++I SAA + L+ VV
Sbjct: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVV 559
Query: 560 IYVLI-GRFCGYKSKHGA-DEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELD 617
+ ++ R G++ +K H+ +GH+ PG++ Y+DP TYEDP +AV EFAKE+D
Sbjct: 560 VIAIVCNRRRGFERADSEYTDKLQHYTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEID 618
Query: 618 ATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQF 677
+ + I++V+GAGEFGEVCSG LKLP K+EI VAIKTLK GYTEKQRRDFL EASIMGQF
Sbjct: 619 ISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQF 678
Query: 678 DHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYL 737
DHPN+I LEGVVTKS PVMI+TE+MENGSLDSFLR++D QFTVIQLVGMLRGIA+GMKYL
Sbjct: 679 DHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYL 738
Query: 738 SDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTSPEA 795
+DM YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDD + YT+ GGKIPIRWT+PEA
Sbjct: 739 ADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEA 798
Query: 796 IAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQ 855
I YRKFTSASDVWSYGIV+WEVMSYGERPYW+M+NQDVI A+++ YRLPPPMDCP+AL+Q
Sbjct: 799 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQ 858
Query: 856 LMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRT 915
LMLDCWQKDRN+RPKF QIV+ LDK+IRNP SLK + ++ + LLD++ D T+F T
Sbjct: 859 LMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNT 918
Query: 916 TGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQ 975
+WL + KE F ++S D ++++ +D+ +VGVT+ G QKKI++SI+ + Q
Sbjct: 919 VDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQ 978
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 1115 bits (2885), Expect = 0.0
Identities = 543/963 (56%), Positives = 706/963 (73%), Gaps = 12/963 (1%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
E L+D++T ELGW + P+ GWEE+SG DE+ IRTYQVCNV + +QNNWL T ++
Sbjct: 19 EETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFIN 78
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
R A +IY E++FT+RDC+S+P V G+CKETFNLYY E+D K + E + K+D
Sbjct: 79 RRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVD 138
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESF+Q+D G R++K+NTE+R GP+ + GFYLAFQD GAC++L+SVRV+FKKCP
Sbjct: 139 TIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPS 198
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
V+N A+FP+T+ +S SLV RG+C+ N++E D P ++YC+ +GEW+VPIG+C+C G
Sbjct: 199 IVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPG 258
Query: 263 YE-ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMA 321
YE E C+AC G +KA C+ CP +S + + S C C Y+RAD DPP +A
Sbjct: 259 YEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPPEVA 318
Query: 322 CTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
CT PS PRNVIS +NETS+IL+W P +TGGR DVT+NIICKKC + + C C NV
Sbjct: 319 CTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVE 378
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
F+PRQ GLT V+++ L AHT YTF+I A+NGVS S P Q +V+ITTNQAAPS V
Sbjct: 379 FVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVP 438
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
+ + + SI+LSW +PE PNGIILDYE++YYEK+ E + ++ R++ I L+P
Sbjct: 439 IMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRP 498
Query: 502 DTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLT--VV 559
+YV Q+RART AGYG S K F+T D S Q+ +IA SAA ++ + V
Sbjct: 499 GMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVA 558
Query: 560 IYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDAT 619
I ++ R Y + +K H+ G PG++ Y+DP TYEDP +AV EFAKE+D +
Sbjct: 559 ISIVCSRKRAYSKEAVYSDKLQHYSTGRGS-PGMKIYIDPFTYEDPNEAVREFAKEIDVS 617
Query: 620 NISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679
+ I++V+GAGEFGEV GRLKLP K+EI VAIKTLK GY+EKQRRDFL EASIMGQFDH
Sbjct: 618 FVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDH 677
Query: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSD 739
PNIIRLEGVVTKS+PVMI+TE+MENG+LDSFLR++D QFTVIQLVGMLRGIA+GMKYL++
Sbjct: 678 PNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAE 737
Query: 740 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTSPEAIA 797
M YVHRDLAARNIL+NSNLVCKVSDFGLSR L+DD + YT+ GGKIP+RWT+PEAIA
Sbjct: 738 MNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA 797
Query: 798 YRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLM 857
YRKFTSASDVWSYGIV+WEVMS+GERPYW+MSNQDVI A+++ YRLPPPMDCPAAL+QLM
Sbjct: 798 YRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLM 857
Query: 858 LDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTG 917
LDCWQKDRN+RP+F +IV+ LDK+IRNP SLK + + A PS LLD+S D T F T
Sbjct: 858 LDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVD 917
Query: 918 DWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQSK 977
DWL+ + ++ F ++S + +++++D+ ++G+T+ G QKKI++SI ++ Q
Sbjct: 918 DWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQIS 977
Query: 978 NGP 980
P
Sbjct: 978 QSP 980
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 1109 bits (2869), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE
Sbjct: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
Query: 61 HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF 120
HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF
Sbjct: 61 HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF 120
Query: 121 NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY
Sbjct: 121 NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Query: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP 240
LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP
Sbjct: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP 240
Query: 241 RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG 300
RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG
Sbjct: 241 RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG 300
Query: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN 360
SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN
Sbjct: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN 360
Query: 361 IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS 420
IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS
Sbjct: 361 IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS 420
Query: 421 PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ 480
PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ
Sbjct: 421 PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ 480
Query: 481 ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD
Sbjct: 481 ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 1102 bits (2849), Expect = 0.0
Identities = 549/967 (56%), Positives = 703/967 (72%), Gaps = 21/967 (2%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
E L+D+K + EL W S+P GWEE+SG DE PIRTYQVCNV + SQNNWLRT ++
Sbjct: 39 EETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIW 98
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
R Q++YVELKFT+RDCNSIP + G+CKETFNL+Y E+D D + E+ + K+D
Sbjct: 99 RRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVD 158
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIA DESF+++D G ++NT++R GP++K GFYLAFQD GAC++L+SVR ++KKC
Sbjct: 159 TIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCAS 214
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
T A+FP+T+ + SLV G+C+ N+ E P ++YC+ +GEW+VP+G C+C G
Sbjct: 215 TTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATG 274
Query: 263 YEE--RGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320
+E + C+ C PG YKA G C CPP+S T + C C NN++RAD D
Sbjct: 275 HEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADS 334
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKC--GWNIKQCEPCSP 378
ACT PS PR VISN+NETS+IL+WS P D GGR D+ +N+ICKKC C C
Sbjct: 335 ACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDD 394
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438
NV F+PRQ GLT V ++ LLAHT YTFE+ AVNGVS S P ++AAV+ITTNQAAPS
Sbjct: 395 NVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPS 454
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISS 498
V T++ +S +S++LSW PE PNG+ILDYE+KY+EK E S + ++ +V +
Sbjct: 455 EVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQLDG 512
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTV 558
L+PD YV Q+RART AGYG SR EFET+ + S + + + + + + +A A ++ V
Sbjct: 513 LRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVV 572
Query: 559 VIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDA 618
+ V+I C K +HG+D + ++ PG++ Y+DP TYEDP +AV EFAKE+D
Sbjct: 573 AV-VVIAIVCLRKQRHGSDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAVREFAKEIDV 630
Query: 619 TNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFD 678
+ + I++V+GAGEFGEVC GRLK P ++E+ VAIKTLKVGYTE+QRRDFL EASIMGQFD
Sbjct: 631 SCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFD 690
Query: 679 HPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLS 738
HPNIIRLEGVVTKS+PVMI+TE+MEN +LDSFLR +D QFTVIQLVGMLRGIA+GMKYLS
Sbjct: 691 HPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLS 750
Query: 739 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDP-EAAYTTR-GGKIPIRWTSPEAI 796
+M YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDDP + YT+ GGKIPIRWT+PEAI
Sbjct: 751 EMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAI 810
Query: 797 AYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQL 856
AYRKFTSASDVWSYGIV+WEVMSYGERPYW+MSNQDVI AV++ YRLPPPMDCP AL+QL
Sbjct: 811 AYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQL 870
Query: 857 MLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTT 916
MLDCW +DRN RPKF QIV+ LDKLIRN SLK+I SA + S LLD++ D TTF T
Sbjct: 871 MLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTV 930
Query: 917 GDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQS 976
GDWL+ + KE F ++S D +A+++ +D+ ++GVT+ G QKKI+SSI+ + Q
Sbjct: 931 GDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQ- 989
Query: 977 KNGPVPV 983
N +PV
Sbjct: 990 MNQTLPV 996
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 972 bits (2512), Expect = 0.0
Identities = 499/964 (51%), Positives = 651/964 (67%), Gaps = 24/964 (2%)
Query: 29 EVNLLDSKTIQGELGWISYP-SHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWV 87
EV LLD GELGW+++P GW+ + + PI Y VCNVM Q+NWLRTNWV
Sbjct: 28 EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGDQDNWLRTNWV 86
Query: 88 PRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIA 147
R A++I++ELKFT+RDCNS P +CKETFNLYY ESD D+G F++ FTKIDTIA
Sbjct: 87 YRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIA 146
Query: 148 ADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVK 207
DE D R +KLN E R VGP+ +KGFYLAFQD+GACVAL+SVRVY+KKCP ++
Sbjct: 147 PDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQ 206
Query: 208 NLAMFPDTVP-MDSQSLVEVRGSCVNNSKEE---DPPRMYCSTEGEWLVPIGKCSCNAGY 263
LA FP+T+ D+ SL V G+CV+++ + PRM+C+ +GEWLVPIG+C C AGY
Sbjct: 207 GLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGY 266
Query: 264 EERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACT 323
E+ CQAC PGF+K C +CP H+ +G+ +C CE +FRA +DP SM CT
Sbjct: 267 EKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCT 326
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
RPPS+P + + V L W+ P D+GGR+D+ +++ C++C +C PC +VR+
Sbjct: 327 RPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYS 386
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
GLT T+VTV+DL H NYTF ++A NGVS L + R F S++ NQ P V
Sbjct: 387 EPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RSFRTASVSINQTEPPKV--- 442
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+ + S S+S+SW P + YEV Y +K + SY + R G +VT+ L PDT
Sbjct: 443 RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN-SYNVRRTEGFSVTLDDLAPDT 501
Query: 504 IYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVL 563
Y+ Q++A T G G S+ EF+T +S E S + + AV ++LL V+ V
Sbjct: 502 TYLVQVQALTQEGQGAGSKVHEFQT------LSPEGSGNLAVIGGVAVGVVLLLVLAGV- 554
Query: 564 IGRFCGYKSKHGADEKR---LHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATN 620
G F + K+ + ++F +L L+TYVDPHTYEDP QAV +F E+ +
Sbjct: 555 -GFFIHRRRKNQRARQSPEDVYFSKSE-QLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSC 612
Query: 621 ISIDKVVGAGEFGEVCSGRLKLPS-KKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679
++ KV+GAGEFGEV G LK S KKE+ VAIKTLK GYTEKQR DFLGEA IMGQF H
Sbjct: 613 VTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSH 672
Query: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSD 739
NIIRLEGV++K KP+MI+TEYMENG+LD FLR+ D +F+V+QLVGMLRGIA+GMKYL++
Sbjct: 673 HNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLAN 732
Query: 740 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYR 799
M YVHRDLAARNIL+NSNLVCKVSDFGLSRVLEDDPEA YTT GGKIPIRWT+PEAI+YR
Sbjct: 733 MNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYR 792
Query: 800 KFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLD 859
KFTSASDVWS+GIV+WEVM+YGERPYWE+SN +V+KA+++G+RLP PMDCP+A+YQLM+
Sbjct: 793 KFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQ 852
Query: 860 CWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDW 919
CWQ++R RPKF IVSILDKLIR P SLK + R S L S + FRT +W
Sbjct: 853 CWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEW 912
Query: 920 LNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQSKNG 979
L + E F Y++ + + +++ DD+K++GV + G QK+I S+ L+ Q
Sbjct: 913 LESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTV 972
Query: 980 PVPV 983
+P+
Sbjct: 973 GIPI 976
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 924 bits (2387), Expect = 0.0
Identities = 479/974 (49%), Positives = 645/974 (66%), Gaps = 38/974 (3%)
Query: 29 EVNLLDSKTIQGELGWISYPSHG--WEEISGVDEHYTPIRTYQVCNVMDH-SQNNWLRTN 85
E LL++K +L W+++P WEE+SG+DE +RTY+VC+V Q +WLRT
Sbjct: 17 EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLRTG 76
Query: 86 WVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFT 141
WVPR A +Y L+FT+ +C S+P +CKETF ++Y ESD D + E+ +
Sbjct: 77 WVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENPYI 136
Query: 142 KIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKK 201
K+DT+AA+ + + K+N + +GP++K GFYLAFQD GAC+AL+S+ +++KK
Sbjct: 137 KVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKK 196
Query: 202 CPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEED--PPRMYCSTEGEWLV-PIGKCS 258
C NL FP+TVP + +V V GSCV ++ P +YC +G+W P+ CS
Sbjct: 197 CAQLTVNLTRFPETVPREL--VVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCS 254
Query: 259 CNAGYE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKD 316
C G+E E C+AC G +K L G C CP +S + GS C+C YFRA D
Sbjct: 255 CAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTD 314
Query: 317 PPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPC 376
P CT PPS+PR+V+S +N +S+ L+WS PL++GGR+D+T+ + C++C C PC
Sbjct: 315 PRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG-GSCAPC 373
Query: 377 SPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAA 436
++ F P L V V L YTFE+ A+NGVS L++ P F V++TT++
Sbjct: 374 GGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREV 433
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEK-QEQETSYTILRARGTNVT 495
P V I+ R+S +S+SL+W P P+G +LDYEVKY+EK E +S L+
Sbjct: 434 PPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAE 493
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIIL 555
+ LK Y+ Q+RAR+ AGYG ++ +T D G Q+ +IA +A V ++L
Sbjct: 494 LRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESE--GWREQLALIAGTAVVGVVL 551
Query: 556 LTVVIYVLI--------GRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQ 607
+ VVI V + GR Y KHG + GH G + Y+DP TYEDP +
Sbjct: 552 VLVVIVVAVLCLRKQSNGREAEYSDKHG------QYLIGH----GTKVYIDPFTYEDPNE 601
Query: 608 AVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDF 667
AV EFAKE+D + + I++V+GAGEFGEVC GRLK P KKE VAIKTLK GYTE+QRR+F
Sbjct: 602 AVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREF 661
Query: 668 LGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGML 727
L EASIMGQF+HPNIIRLEGVVT S PVMI+TE+MENG+LDSFLR +D QFTVIQLVGML
Sbjct: 662 LSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGML 721
Query: 728 RGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGK 785
RGIASGM+YL++M YVHRDLAARNIL+NSNLVCKVSDFGLSR LE++ + YT+ GGK
Sbjct: 722 RGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGK 781
Query: 786 IPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPP 845
IPIRWT+PEAIA+RKFTSASD WSYGIV+WEVMS+GERPYW+MSNQDVI A+++ YRLPP
Sbjct: 782 IPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPP 841
Query: 846 PMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQ 905
P DCP +L+QLMLDCWQKDRN RP+F Q+VS LDK+IRNP SLKI+ S+ LLDQ
Sbjct: 842 PPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQ 901
Query: 906 SNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKI 965
+ F + G+WL + +E F + S + +++IS +D+ ++GVT+ G QKKI
Sbjct: 902 RQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKI 961
Query: 966 ISSIKALETQSKNG 979
++S++ +++Q+K G
Sbjct: 962 LASVQHMKSQAKPG 975
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 923 bits (2386), Expect = 0.0
Identities = 471/994 (47%), Positives = 663/994 (66%), Gaps = 36/994 (3%)
Query: 4 QLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYT 63
QL + LLL G P + EV LLDSK Q ELGW + PS+GWEEISGVDEH
Sbjct: 18 QLCLALLL--------GPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDR 69
Query: 64 PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLY 123
PIRTYQVCNV++ +Q+NWL+T W+ R Q+I+VEL+FTLRDC+SIP GTCKETFN+Y
Sbjct: 70 PIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVY 129
Query: 124 YMESDDDHG---VKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Y+E++ D G + + KIDTIAADESFTQ DLG+R +KLNTE+RE+GP++++GF+
Sbjct: 130 YLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFH 189
Query: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQS-LVEVRGSCVNNSKEE-- 237
LAFQDVGACVALVSVRVY+K+C TV+ LA FP T + S LVEV G+CV +S+ E
Sbjct: 190 LAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPG 249
Query: 238 DPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQ 297
PPRM+C +GEWLVP+G+CSC+AG++ERG C+AC PGFYK C+ CP HS
Sbjct: 250 SPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRAL 309
Query: 298 EDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSW--PLDTGGRK 355
E+ S C C+++Y R+ DPPS +CTRPPS+PR++ +++ + ++L W P D+GGR
Sbjct: 310 ENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRS 369
Query: 356 DVTFNIICKKCGWN--IKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
DVT++++C +CG CEPC P V FLPRQ GL T+ L YT + A+N
Sbjct: 370 DVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALN 429
Query: 414 GVS-ELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEP---EHPNGIILD 469
GVS ++ +A V+++T AP I++DR S+SLSW+EP P +
Sbjct: 430 GVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTE 489
Query: 470 YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKF----E 525
YE++YYEK + E +Y++++ VT+++LKP T YVFQIRA + G ++ F E
Sbjct: 490 YEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRA-ASPGPSWEAQSFNPSIE 548
Query: 526 FETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVLI--GRFCGYKSKHGA--DEKRL 581
+T ++ S S + S +++ + A+++L V+ VL R C Y G DE+ L
Sbjct: 549 VQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEEL 608
Query: 582 HFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLK 641
+F H K+P RT++DP + D QAVH FAKELDA ++++++ +G G FGE+C G L+
Sbjct: 609 YF---HFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQ 665
Query: 642 LPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEY 701
LP ++E+ VA+ L+ ++ QR FL EA +GQFDH +I+RLEGVVT+ +MIVTEY
Sbjct: 666 LPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEY 725
Query: 702 MENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCK 761
M +G+LD FLR+H+ Q QL+G+L G+AS MKYLS+MGYVHR LAAR++L++S+LVCK
Sbjct: 726 MSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCK 785
Query: 762 VSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYG 821
+S FG R D EA YTT G+ P W +PE + + F+SASDVWS+GI++WEVM++G
Sbjct: 786 ISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFG 843
Query: 822 ERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
ERPYW+MS QDVIKAV++G+RLPPP +CP L++LMLDCWQKD RP+F QI SIL K+
Sbjct: 844 ERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKM 903
Query: 882 IRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCD 941
+++P K + RP L D++ +F + G WL + K+ F Y S +
Sbjct: 904 VQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLE 963
Query: 942 TIAKISTDDMKKVGVTVVGPQKKIISSIKALETQ 975
+A+++ D+ +G+++ ++ ++S I AL+ +
Sbjct: 964 AVAEMTAQDLVSLGISLAEHREALLSGISALQAR 997
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 772 bits (1993), Expect = 0.0
Identities = 427/983 (43%), Positives = 602/983 (61%), Gaps = 35/983 (3%)
Query: 8 LLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWI-SYPSHGWEEISGVDEHYTPIR 66
L+LL C+ L + EV L+D+ QGELGW+ P GW E + + TP+
Sbjct: 11 LVLLLCAPLPPGAR-----AKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLY 64
Query: 67 TYQVCNVMDHSQ-NNWLRTNWVPRNS-AQKIYVELKFTLRDCNSIPLVLGT--CKETFNL 122
YQ C + ++WLR+NW+ R A +++VEL+FT+RDC S P G CKETFNL
Sbjct: 65 MYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNL 124
Query: 123 YYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLA 182
YMESD D G++ R F K+ T+AAD+SFT DL +KLN E +G + ++G YLA
Sbjct: 125 LYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLA 184
Query: 183 FQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEED---- 238
F + GACVALVSVRV++++CP T+ LA FPDT+P + LVEV G+C+ +++
Sbjct: 185 FHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPA-GLVEVAGTCLPHARASPRPSG 243
Query: 239 PPRMYCSTEGEWLVPIGKCSCNAGYEERGF--MCQACRPGFYKALDGNMKCAKCPPHSST 296
PRM+CS +GEWLVP+G+C C GYEE G C AC G Y+ C CP S+
Sbjct: 244 APRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTA 303
Query: 297 QEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKD 356
+ +G+ C CE+ ++RA + P +ACT PPS+PRN+ + + T + L W P DTGGR+D
Sbjct: 304 ESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQD 363
Query: 357 VTFNIICKKCGWNIKQ---CEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
V +++ C +C + C+PC V F P GLT V V L + NYTF ++A N
Sbjct: 364 VRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQN 423
Query: 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSW--QEPEHPNGIILDYE 471
GVS L S +VSI+ A L+++ + + L+W P P G L YE
Sbjct: 424 GVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYE 482
Query: 472 VKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+ + Q++E +L R V ++ L+PDT Y+ ++R T G G S EF TSP
Sbjct: 483 L-HVLNQDEERYQMVLEPR---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPP 538
Query: 532 -SFSISGESSQVVMIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKL 590
S ++G V+ + A++L +V + + + R + KL
Sbjct: 539 VSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQ----RQRQQRQRDRATDVDREDKL 594
Query: 591 PGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISV 650
L+ YVD YEDP Q +F +ELD + +D V+G GEFGEV G L+LPS+ +V
Sbjct: 595 -WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTV 653
Query: 651 AIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSF 710
AIKTLK Q +FL EA+IMGQF HP+I+ LEGVVTK KP+MI+TE+MENG+LD+F
Sbjct: 654 AIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAF 713
Query: 711 LRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRV 770
LR+ + Q QLV ML+GIASGM YLS+ YVHRDLAARNIL+N NL CKVSDFGL+R+
Sbjct: 714 LREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 773
Query: 771 LEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSN 830
L DD + Y T+GGKIPIRWT+PEAIA+R FT+ASDVWS+GIV+WEV+S+G++PY EMSN
Sbjct: 774 L-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSN 832
Query: 831 QDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKI 890
Q+V+K++++GYRLPPP+DCPA LY+LM +CW DR RP F+++ + L++L+ NP SL+
Sbjct: 833 QEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRT 892
Query: 891 ITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDD 950
I + R + L S D +RT +WL + F + + + +++ +D
Sbjct: 893 IANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAED 952
Query: 951 MKKVGVTVVGPQKKIISSIKALE 973
+ ++G+T+ G QK+I+ SI+ +
Sbjct: 953 LTQMGITLPGHQKRILCSIQGFK 975
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 763 bits (1969), Expect = 0.0
Identities = 411/1022 (40%), Positives = 611/1022 (59%), Gaps = 76/1022 (7%)
Query: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
M C L +LLL+S SVL + E LLD+ E+GW++YP GW+E+S +D+
Sbjct: 16 MVCSLWVLLLVS-SVL----------ALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDD 64
Query: 61 HYTPIRTYQVCNVMDH----SQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTC 116
RT++ C+V Q+NWL+T++V R AQ+ ++ L F++R C+S+ + GTC
Sbjct: 65 QRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTC 124
Query: 117 KETFNLYYMESDD----DHGVKFREHQFTKIDTIAADESFTQMD---------------- 156
+ETF LYY ++++ D + ++TK+DTIAADESF
Sbjct: 125 RETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPH 184
Query: 157 -LGDRI-LKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPD 214
G R L+LN + R GP+ ++GFY+AFQD GAC+ALV+VR++ CP +++ A FP+
Sbjct: 185 GAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPE 244
Query: 215 TVPMDS--QSLVEVRGSCVNNSKEED----------PPRMYCSTEGEWLVPIGKCSCNAG 262
T + SLV G+CV +++ E+ PPR++C+ EG+W+V +G C C G
Sbjct: 245 TQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPG 304
Query: 263 YEE-RGFM-CQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320
Y+ RG CQAC G YK+ GN C+ CP S + C C ++RA DPP
Sbjct: 305 YQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEA 364
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQ-------C 373
CT PPS+P+ + + ++++L W P + GGR D+ FN++CK+C + C
Sbjct: 365 PCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTC 424
Query: 374 EPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTN 433
C V F PRQ GLT + V V L AH Y E+ AVNGVSELS P Q AA++++T+
Sbjct: 425 HRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTS 484
Query: 434 QAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTN 493
PS V + + + NSI++SW +P+ NG ILDY+++YY++ E E+ L +
Sbjct: 485 HEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNT 544
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISG--ESSQVVMIAISAAV 551
T++ L P IY FQ+RARTAAG+G K F+T P S E +V+ +I A+
Sbjct: 545 ATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGAL 604
Query: 552 AIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHE 611
A +LL + VL F + G E+ + + L G++ Y+DP TYEDP QA+ E
Sbjct: 605 AFLLLAAIT-VLAVVFQRKRRGTGYTEQLQQYSSPGL---GVKYYIDPSTYEDPCQAIRE 660
Query: 612 FAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEA 671
A+E+D I I++V+G G FGEV GRL+ ++E +VAI+ L G E + FLG A
Sbjct: 661 LAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRA 720
Query: 672 SIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIA 731
+++GQF HPNI+RLEGVVTKS+P+M++TE+ME G LDSFLR+ + QF+ +QLV M RG+A
Sbjct: 721 AVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVA 780
Query: 732 SGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWT 791
+ M+YLS +VHR L+A ++L+NS+LVCKV+ G ++ +G +RW
Sbjct: 781 AAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG------------HSPQGPSCLLRWA 828
Query: 792 SPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPA 851
+PE IA+ K T++SDVWS+GI++WEVMSYGERPYW+MS Q+V+ A+++ +RLPPP CP
Sbjct: 829 APEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPP 888
Query: 852 ALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDIT 911
L+ LMLD WQKDR RP F+Q+V+ DK+IR P +L+ RPS LL +D
Sbjct: 889 GLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFP 948
Query: 912 TFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKA 971
+ WL+ + ++ F+ + +A++S +D+ +G+T+ G QKK++ I+
Sbjct: 949 CLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQL 1008
Query: 972 LE 973
L+
Sbjct: 1009 LQ 1010
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 554 bits (1427), Expect = e-157
Identities = 252/408 (61%), Positives = 318/408 (77%), Gaps = 1/408 (0%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
EVNLLD+ TI G+ GW++YP+HGW+ I+ VDE + PI TYQVCNVM +QNNWLRT+WVP
Sbjct: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAA 148
R+ A+++Y E+KFTLRDCNS+P VLGTCKETFNLYY+ESD D G +E QF KIDTIAA
Sbjct: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAA 150
Query: 149 DESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKN 208
DESFT DLG R LKLNTE+R VGP++K+GFYLAFQD+GAC+A++S+R+Y+KKCP V+N
Sbjct: 151 DESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRN 210
Query: 209 LAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERG 267
LA F + V DS SLVEVRG CV +S+E D P+MYCS EGEWLVPIGKC C+AGYEER
Sbjct: 211 LAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERR 270
Query: 268 FMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPS 327
C AC GFYK+ G+ CA+CPPHS + + C C+ +Y+RA DPPS ACTRPPS
Sbjct: 271 DACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPS 330
Query: 328 SPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
+P N+IS++N TSV L+W+ PLD GGR D+T+N +C++C W + +CE C RF+P+Q
Sbjct: 331 APVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQT 390
Query: 388 GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
L ++ V +LLAH NY+F I+AVNGVS+LS PR+ A V+ITTNQA
Sbjct: 391 SLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 324 bits (831), Expect = 2e-88
Identities = 161/274 (58%), Positives = 206/274 (75%), Gaps = 14/274 (5%)
Query: 4 QLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYT 63
QL + LLL G P + EV LLDSK Q ELGW + PS+GWEEISGVDEH
Sbjct: 18 QLCLALLL--------GPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDR 69
Query: 64 PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLY 123
PIRTYQVCNV++ +Q+NWL+T W+ R Q+I+VEL+FTLRDC+SIP GTCKETFN+Y
Sbjct: 70 PIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVY 129
Query: 124 YMESDDDHG---VKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Y+E++ D G + + KIDTIAADESFTQ DLG+R +KLNTE+RE+GP++++GF+
Sbjct: 130 YLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFH 189
Query: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDS-QSLVEVRGSCVNNSKEE-- 237
LAFQDVGACVALVSVRVY+K+C TV+ LA FP T + +LVEV G+CV +S+ E
Sbjct: 190 LAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPG 249
Query: 238 DPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQ 271
PPRM+C +GEWLVP+G+CSC+AG++ERG C+
Sbjct: 250 SPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCE 283
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 231 bits (590), Expect = 2e-60
Identities = 165/526 (31%), Positives = 264/526 (50%), Gaps = 41/526 (7%)
Query: 368 WNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE-LSSPPRQFA 426
+NI E F + TV +++L T Y +I + N +E L F
Sbjct: 763 YNITDPEELETEYPFFESRVDNKERTV-ISNLRPFTLYRIDIHSCNHEAEKLGCSASNFV 821
Query: 427 AVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKY---YEKQEQETS 483
+ A + + NSI L W EPE+PNG+IL YE+KY E Q + S
Sbjct: 822 FARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVS 881
Query: 484 YTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVV 543
R G ++ L P Y +I+A + +G G+ T P F + ++
Sbjct: 882 RQEYRKYG-GAKLNRLNPGN-YTARIQATSLSGNGS-------WTDPVFFYVQAKTGYEN 932
Query: 544 MIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYE 603
I + A+ + +L +V ++I + ++ ++ + GNG L Y
Sbjct: 933 FIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNS-----RLGNGVLYASVNPEYFSAADVY 987
Query: 604 DPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLK--LPSKKEISVAIKTLKVGYTE 661
P + E A+E I++ + +G G FG V G K + + E VAIKT+ +
Sbjct: 988 VPDE--WEVARE----KITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASM 1041
Query: 662 KQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQF--- 718
++R +FL EAS+M +F+ +++RL GVV++ +P +++ E M G L S+LR +
Sbjct: 1042 RERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENN 1101
Query: 719 ------TVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLE 772
++ +++ M IA GM YL+ +VHRDLAARN ++ + K+ DFG++R
Sbjct: 1102 PVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTR--- 1158
Query: 773 DDPEAAYTTRGGK--IPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSN 830
D E Y +GGK +P+RW SPE++ FT+ SDVWS+G+VLWE+ + E+PY +SN
Sbjct: 1159 DIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSN 1218
Query: 831 QDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 876
+ V++ V EG L P +CP L++LM CWQ + RP F +I+S
Sbjct: 1219 EQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIS 1264
Score = 31.2 bits (69), Expect = 5.0
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 430 ITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQE 481
I TN + PS L + S + + + W P PNG L Y + +++Q Q+
Sbjct: 604 IRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNG-NLSYYIVRWQRQPQD 654
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 228 bits (581), Expect = 2e-59
Identities = 119/277 (42%), Positives = 175/277 (63%), Gaps = 12/277 (4%)
Query: 605 PTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQR 664
P + + A E+ ++ ++K +GAG+FGEV K VA+KT+K G +
Sbjct: 246 PQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYN----KHTKVAVKTMKPGSMSVEA 301
Query: 665 RDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVI-QL 723
FL EA++M H +++L VVTK +P+ I+TE+M GSL FL+ + + +L
Sbjct: 302 --FLAEANVMKTLQHDKLVKLHAVVTK-EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKL 358
Query: 724 VGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 782
+ IA GM ++ Y+HRDL A NIL++++LVCK++DFGL+RV+ED+ YT R
Sbjct: 359 IDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE---YTARE 415
Query: 783 GGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYR 842
G K PI+WT+PEAI + FT SDVWS+GI+L E+++YG PY MSN +VI+A++ GYR
Sbjct: 416 GAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYR 475
Query: 843 LPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879
+P P +CP LY +M+ CW+ RP FE I S+LD
Sbjct: 476 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 223 bits (568), Expect = 7e-58
Identities = 118/267 (44%), Positives = 174/267 (65%), Gaps = 12/267 (4%)
Query: 615 ELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIM 674
E+ ++ + K +G G+FGEV G +K VAIKTLK G + FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318
Query: 675 GQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVI-QLVGMLRGIASG 733
+ H +++L VV++ +P+ IVTEYM GSL FL+ + + + LV M +A+G
Sbjct: 319 KKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377
Query: 734 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR-GGKIPIRWTS 792
M Y+ M Y+HRDL + NIL+ + L+CK++DFGL+R++ED+ YT R G K PI+WT+
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTA 434
Query: 793 PEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAA 852
PEA Y +FT SDVWS+GI+L E+++ G PY M+N++V++ V+ GYR+P P DCP +
Sbjct: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPIS 494
Query: 853 LYQLMLDCWQKDRNNRPKFEQIVSILD 879
L++LM+ CW+KD RP FE + S L+
Sbjct: 495 LHELMIHCWKKDPEERPTFEYLQSFLE 521
>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform B [Homo sapiens]
Length = 491
Score = 223 bits (567), Expect = 9e-58
Identities = 117/269 (43%), Positives = 172/269 (63%), Gaps = 11/269 (4%)
Query: 613 AKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEAS 672
A E+ +I + K +GAG+FGEV G +K VA+KTLK G Q FL EA+
Sbjct: 218 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 271
Query: 673 IMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVI-QLVGMLRGIA 731
+M H ++RL VVT+ +P+ I+TEYM GSL FL+ + ++ +L+ IA
Sbjct: 272 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 331
Query: 732 SGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR-GGKIPIRW 790
GM Y+ Y+HRDL A N+L++ +L+CK++DFGL+RV+ED+ YT R G K PI+W
Sbjct: 332 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTAREGAKFPIKW 388
Query: 791 TSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCP 850
T+PEAI + FT SDVWS+GI+L+E+++YG+ PY +N DV+ A+ +GYR+P +CP
Sbjct: 389 TAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCP 448
Query: 851 AALYQLMLDCWQKDRNNRPKFEQIVSILD 879
LY +M CW++ RP F+ + S+LD
Sbjct: 449 DELYDIMKMCWKEKAEERPTFDYLQSVLD 477
>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform A [Homo sapiens]
Length = 512
Score = 223 bits (567), Expect = 9e-58
Identities = 117/269 (43%), Positives = 172/269 (63%), Gaps = 11/269 (4%)
Query: 613 AKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEAS 672
A E+ +I + K +GAG+FGEV G +K VA+KTLK G Q FL EA+
Sbjct: 239 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 292
Query: 673 IMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVI-QLVGMLRGIA 731
+M H ++RL VVT+ +P+ I+TEYM GSL FL+ + ++ +L+ IA
Sbjct: 293 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 352
Query: 732 SGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR-GGKIPIRW 790
GM Y+ Y+HRDL A N+L++ +L+CK++DFGL+RV+ED+ YT R G K PI+W
Sbjct: 353 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTAREGAKFPIKW 409
Query: 791 TSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCP 850
T+PEAI + FT SDVWS+GI+L+E+++YG+ PY +N DV+ A+ +GYR+P +CP
Sbjct: 410 TAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCP 469
Query: 851 AALYQLMLDCWQKDRNNRPKFEQIVSILD 879
LY +M CW++ RP F+ + S+LD
Sbjct: 470 DELYDIMKMCWKEKAEERPTFDYLQSVLD 498
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 222 bits (566), Expect = 1e-57
Identities = 125/281 (44%), Positives = 178/281 (63%), Gaps = 12/281 (4%)
Query: 601 TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT 660
T + TQ + + A E+ ++ ++ +G G FGEV G +K VAIKTLK G
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312
Query: 661 EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV 720
+ FL EA IM + H ++ L VV++ +P+ IVTE+M GSL FL++ D ++
Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLK 369
Query: 721 I-QLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 779
+ QLV M IA GM Y+ M Y+HRDL A NIL+ NLVCK++DFGL+R++ED+ Y
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---Y 426
Query: 780 TTR-GGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVD 838
T R G K PI+WT+PEA Y +FT SDVWS+GI+ E+++ G PY M N++V++ V+
Sbjct: 427 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVE 486
Query: 839 EGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879
GYR+P P CP +L++LM CW+KD + RP FE I S L+
Sbjct: 487 RGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 222 bits (565), Expect = 2e-57
Identities = 112/282 (39%), Positives = 170/282 (60%), Gaps = 7/282 (2%)
Query: 601 TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT 660
TY P+ +E +E I + + +G G+FG+V G P ++VAIKT K +
Sbjct: 428 TYTMPSTRDYEIQRE----RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTS 483
Query: 661 EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV 720
+ R FL EA M QFDHP+I++L GV+T++ PV I+ E G L SFL+ +
Sbjct: 484 DSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDL 542
Query: 721 IQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYT 780
L+ +++ + YL +VHRD+AARN+L++SN K+ DFGLSR +ED Y
Sbjct: 543 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYK 600
Query: 781 TRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEG 840
GK+PI+W +PE+I +R+FTSASDVW +G+ +WE++ +G +P+ + N DVI ++ G
Sbjct: 601 ASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENG 660
Query: 841 YRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLI 882
RLP P +CP LY LM CW D + RP+F ++ + L ++
Sbjct: 661 ERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 702
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 222 bits (565), Expect = 2e-57
Identities = 112/282 (39%), Positives = 170/282 (60%), Gaps = 7/282 (2%)
Query: 601 TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT 660
TY P+ +E +E I + + +G G+FG+V G P ++VAIKT K +
Sbjct: 406 TYTMPSTRDYEIQRE----RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTS 461
Query: 661 EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV 720
+ R FL EA M QFDHP+I++L GV+T++ PV I+ E G L SFL+ +
Sbjct: 462 DSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDL 520
Query: 721 IQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYT 780
L+ +++ + YL +VHRD+AARN+L++SN K+ DFGLSR +ED Y
Sbjct: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYK 578
Query: 781 TRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEG 840
GK+PI+W +PE+I +R+FTSASDVW +G+ +WE++ +G +P+ + N DVI ++ G
Sbjct: 579 ASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENG 638
Query: 841 YRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLI 882
RLP P +CP LY LM CW D + RP+F ++ + L ++
Sbjct: 639 ERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 221 bits (563), Expect = 3e-57
Identities = 124/281 (44%), Positives = 176/281 (62%), Gaps = 12/281 (4%)
Query: 601 TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT 660
T + TQ + + A E+ ++ ++ +G G FGEV G ++ VAIKTLK G
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305
Query: 661 EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV 720
+ FL EA +M + H +++L VV++ +P+ IVTEYM GSL FL+ ++
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLR 362
Query: 721 I-QLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 779
+ QLV M IASGM Y+ M YVHRDL A NIL+ NLVCKV+DFGL+R++ED+ Y
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---Y 419
Query: 780 TTR-GGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVD 838
T R G K PI+WT+PEA Y +FT SDVWS+GI+L E+ + G PY M N++V+ V+
Sbjct: 420 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE 479
Query: 839 EGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879
GYR+P P +CP +L+ LM CW+K+ RP FE + + L+
Sbjct: 480 RGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520
>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 221 bits (563), Expect = 3e-57
Identities = 124/281 (44%), Positives = 176/281 (62%), Gaps = 12/281 (4%)
Query: 601 TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT 660
T + TQ + + A E+ ++ ++ +G G FGEV G ++ VAIKTLK G
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305
Query: 661 EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV 720
+ FL EA +M + H +++L VV++ +P+ IVTEYM GSL FL+ ++
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLR 362
Query: 721 I-QLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 779
+ QLV M IASGM Y+ M YVHRDL A NIL+ NLVCKV+DFGL+R++ED+ Y
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---Y 419
Query: 780 TTR-GGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVD 838
T R G K PI+WT+PEA Y +FT SDVWS+GI+L E+ + G PY M N++V+ V+
Sbjct: 420 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE 479
Query: 839 EGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879
GYR+P P +CP +L+ LM CW+K+ RP FE + + L+
Sbjct: 480 RGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520
>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
Length = 534
Score = 221 bits (562), Expect = 3e-57
Identities = 119/276 (43%), Positives = 177/276 (64%), Gaps = 12/276 (4%)
Query: 606 TQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRR 665
T + + A E+ ++ ++K +G G F EV G +K VAIKTLK G +
Sbjct: 253 TSGLAKDAWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTK----VAIKTLKPGTMSPE-- 306
Query: 666 DFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVI-QLV 724
FL EA IM + H +++L VV++ +P+ IVTEYM GSL FL+ + + + LV
Sbjct: 307 SFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLV 365
Query: 725 GMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR-G 783
M +A+GM Y+ M Y+HRDL + NIL+ + L+CK++DFGL+R++ED+ YT R G
Sbjct: 366 DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE---YTARQG 422
Query: 784 GKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRL 843
K PI+WT+PEA Y +FT SDVWS+GI+L E+++ G PY M+N++V++ V+ GYR+
Sbjct: 423 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM 482
Query: 844 PPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879
P P DCP +L++LM+ CW+KD RP FE + S L+
Sbjct: 483 PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLE 518
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,868,284
Number of Sequences: 37866
Number of extensions: 1773174
Number of successful extensions: 8068
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 641
Number of HSP's successfully gapped in prelim test: 318
Number of HSP's that attempted gapping in prelim test: 4229
Number of HSP's gapped (non-prelim): 2165
length of query: 983
length of database: 18,247,518
effective HSP length: 112
effective length of query: 871
effective length of database: 14,006,526
effective search space: 12199684146
effective search space used: 12199684146
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.