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Search of human proteins with 21314720
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21314720 Smad nuclear interacting protein [Homo sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21314720 Smad nuclear interacting protein [Homo sapiens] 811 0.0
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 68 2e-11
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 68 2e-11
gi|13699256 protein phosphatase 1 regulatory inhibitor subunit 8... 67 4e-11
gi|155722990 solute carrier family 4 (anion exchanger), member 1... 65 1e-10
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 60 3e-09
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 60 4e-09
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 60 4e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 58 1e-08
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 58 2e-08
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 57 3e-08
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi... 57 3e-08
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 54 2e-07
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 54 3e-07
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 54 3e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 54 3e-07
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 53 4e-07
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 53 4e-07
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 53 5e-07
gi|50083281 KIAA1853 protein [Homo sapiens] 53 5e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 52 9e-07
gi|60097902 filaggrin [Homo sapiens] 52 1e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 52 1e-06
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 51 2e-06
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 50 3e-06
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 50 5e-06
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 49 6e-06
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 49 8e-06
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 49 8e-06
>gi|21314720 Smad nuclear interacting protein [Homo sapiens]
Length = 396
Score = 811 bits (2094), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEP 60
MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEP
Sbjct: 1 MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEP 60
Query: 61 ARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRE 120
ARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRE
Sbjct: 61 ARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRE 120
Query: 121 DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE 180
DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE
Sbjct: 121 DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE 180
Query: 181 FYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFR 240
FYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFR
Sbjct: 181 FYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFR 240
Query: 241 GVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCS 300
GVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCS
Sbjct: 241 GVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCS 300
Query: 301 KQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKF 360
KQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKF
Sbjct: 301 KQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKF 360
Query: 361 GFSSREYVLLHESSDTSEIDRKDDEDEEEEEEVSDS 396
GFSSREYVLLHESSDTSEIDRKDDEDEEEEEEVSDS
Sbjct: 361 GFSSREYVLLHESSDTSEIDRKDDEDEEEEEEVSDS 396
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/195 (23%), Positives = 90/195 (46%), Gaps = 10/195 (5%)
Query: 31 QERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGR-RS 89
Q +S + P + + + GG T +RS + + R RS K ++++ R RS
Sbjct: 286 QSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRR--KRSQSKHRSRSHNRSRS 343
Query: 90 KSPRSKRNRSPHHSTVKVKQEREDHPR-RGREDRQHREPSEQEHRRARNSDRDRHRGHSH 148
+ +R++SPH K ++ R+ R R+ R+ +E R + DR++ R
Sbjct: 344 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 403
Query: 149 QRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPR 208
+R ER G+ + RD++ + + +++E++ R +EH + D E ++ +
Sbjct: 404 EREKEKER---GKNKDRDKEREKDREKDKEKDREREREKEHEKDRD---KEKEKEQDKEK 457
Query: 209 PGGNNKEKEVPAKEK 223
++ KE+ K K
Sbjct: 458 EREKDRSKEIDEKRK 472
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/210 (22%), Positives = 80/210 (38%), Gaps = 36/210 (17%)
Query: 42 AHRRPDHSGGSPSPPTSEPARSGHRG---NRARGV------SRSPPKKKNKASGRRSKSP 92
+H R S S + ++S HR NR+R S+SP KK++K+ RR
Sbjct: 310 SHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS 369
Query: 93 RSKRNRSPHHSTVKVKQ-----------------EREDHPRRGR---------EDRQHRE 126
RS + K+K+ ERE RG+ +DR+ +
Sbjct: 370 RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 429
Query: 127 PSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARR 186
++E R + ++DR + ++ ER + ++ ++ +++ R YNA R
Sbjct: 430 EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS-YNASR 488
Query: 187 REHRQRNDVGGGGSESQELVPRPGGNNKEK 216
R + S S PR K K
Sbjct: 489 RSRSSSRERRRRRSRSSSRSPRTSKTIKRK 518
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/121 (28%), Positives = 63/121 (52%), Gaps = 18/121 (14%)
Query: 60 PARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGR 119
P RS + R+R SR ++++++S S+SPR+ + T+K K R P R R
Sbjct: 480 PPRSYNASRRSRSSSRERRRRRSRSS---SRSPRTSK-------TIKRKSSRSPSP-RSR 528
Query: 120 EDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEER 179
+ + E++H R R+R R S R++SN+R G + ++++ +L+ +E +
Sbjct: 529 NKKDKKREKERDHISER---RERERSTS-MRKSSNDRDGK---EKLEKNSTSLKEKEHNK 581
Query: 180 E 180
E
Sbjct: 582 E 582
Score = 41.6 bits (96), Expect = 0.001
Identities = 52/232 (22%), Positives = 84/232 (36%), Gaps = 26/232 (11%)
Query: 2 KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPA 61
K KS R SR R D +K++ E R + E
Sbjct: 357 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE----------KERE 406
Query: 62 RSGHRG-NRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRE 120
+ RG N+ R R ++K+K R + + + +E+E R +E
Sbjct: 407 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466
Query: 121 -------DRQHREP--SEQEHRRARNSDRDRH----RGHSHQRRTSN--ERPGSGQGQGR 165
D++ R P S RR+R+S R+R R S RTS +R S R
Sbjct: 467 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR 526
Query: 166 DRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKE 217
R+ ++ + ++E R RE + +E + + + KEKE
Sbjct: 527 SRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 578
Score = 38.9 bits (89), Expect = 0.008
Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 13/146 (8%)
Query: 44 RRPDHSGGSP--SPPTSEPARSG---HRGNRARGVSRSPPKKKN-KASGRRSKSPRS--- 94
R+ D +P S S +RS R R+R SRSP K K RS SPRS
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 95 ---KRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRR 151
KR + H + + ++ER R+ DR +E E+ + + ++ S +
Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 152 TSNERPGSGQGQGRDRDTQNLQAQEE 177
+++ + + + N Q EE
Sbjct: 591 V-DDKDAPRTEENKIQHNGNCQLNEE 615
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/195 (23%), Positives = 90/195 (46%), Gaps = 10/195 (5%)
Query: 31 QERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGR-RS 89
Q +S + P + + + GG T +RS + + R RS K ++++ R RS
Sbjct: 170 QSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRR--KRSQSKHRSRSHNRSRS 227
Query: 90 KSPRSKRNRSPHHSTVKVKQEREDHPR-RGREDRQHREPSEQEHRRARNSDRDRHRGHSH 148
+ +R++SPH K ++ R+ R R+ R+ +E R + DR++ R
Sbjct: 228 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 287
Query: 149 QRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPR 208
+R ER G+ + RD++ + + +++E++ R +EH + D E ++ +
Sbjct: 288 EREKEKER---GKNKDRDKEREKDREKDKEKDREREREKEHEKDRD---KEKEKEQDKEK 341
Query: 209 PGGNNKEKEVPAKEK 223
++ KE+ K K
Sbjct: 342 EREKDRSKEIDEKRK 356
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/210 (22%), Positives = 80/210 (38%), Gaps = 36/210 (17%)
Query: 42 AHRRPDHSGGSPSPPTSEPARSGHRG---NRARGV------SRSPPKKKNKASGRRSKSP 92
+H R S S + ++S HR NR+R S+SP KK++K+ RR
Sbjct: 194 SHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS 253
Query: 93 RSKRNRSPHHSTVKVKQ-----------------EREDHPRRGR---------EDRQHRE 126
RS + K+K+ ERE RG+ +DR+ +
Sbjct: 254 RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 313
Query: 127 PSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARR 186
++E R + ++DR + ++ ER + ++ ++ +++ R YNA R
Sbjct: 314 EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS-YNASR 372
Query: 187 REHRQRNDVGGGGSESQELVPRPGGNNKEK 216
R + S S PR K K
Sbjct: 373 RSRSSSRERRRRRSRSSSRSPRTSKTIKRK 402
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/121 (28%), Positives = 63/121 (52%), Gaps = 18/121 (14%)
Query: 60 PARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGR 119
P RS + R+R SR ++++++S S+SPR+ + T+K K R P R R
Sbjct: 364 PPRSYNASRRSRSSSRERRRRRSRSS---SRSPRTSK-------TIKRKSSRSPSP-RSR 412
Query: 120 EDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEER 179
+ + E++H R R+R R S R++SN+R G + ++++ +L+ +E +
Sbjct: 413 NKKDKKREKERDHISER---RERERSTS-MRKSSNDRDGK---EKLEKNSTSLKEKEHNK 465
Query: 180 E 180
E
Sbjct: 466 E 466
Score = 41.6 bits (96), Expect = 0.001
Identities = 52/232 (22%), Positives = 84/232 (36%), Gaps = 26/232 (11%)
Query: 2 KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPA 61
K KS R SR R D +K++ E R + E
Sbjct: 241 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE----------KERE 290
Query: 62 RSGHRG-NRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRE 120
+ RG N+ R R ++K+K R + + + +E+E R +E
Sbjct: 291 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350
Query: 121 -------DRQHREP--SEQEHRRARNSDRDRH----RGHSHQRRTSN--ERPGSGQGQGR 165
D++ R P S RR+R+S R+R R S RTS +R S R
Sbjct: 351 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR 410
Query: 166 DRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKE 217
R+ ++ + ++E R RE + +E + + + KEKE
Sbjct: 411 SRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 462
Score = 38.9 bits (89), Expect = 0.008
Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 13/146 (8%)
Query: 44 RRPDHSGGSP--SPPTSEPARSG---HRGNRARGVSRSPPKKKN-KASGRRSKSPRS--- 94
R+ D +P S S +RS R R+R SRSP K K RS SPRS
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 95 ---KRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRR 151
KR + H + + ++ER R+ DR +E E+ + + ++ S +
Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 152 TSNERPGSGQGQGRDRDTQNLQAQEE 177
+++ + + + N Q EE
Sbjct: 475 V-DDKDAPRTEENKIQHNGNCQLNEE 499
>gi|13699256 protein phosphatase 1 regulatory inhibitor subunit 8
isoform alpha [Homo sapiens]
Length = 351
Score = 66.6 bits (161), Expect = 4e-11
Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 11/145 (7%)
Query: 249 PPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQY 308
P A P L K D+++ + I + YL GR+ + D IDH SCS+ HA Y
Sbjct: 17 PTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVY 76
Query: 309 RLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYV 368
+ ++IDL S +GTFL + R+EP + ++ + FG S+R Y
Sbjct: 77 HK-----------HLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYT 125
Query: 369 LLHESSDTSEIDRKDDEDEEEEEEV 393
L + + D++ E++E+
Sbjct: 126 LREKPQTLPSAVKGDEKMGGEDDEL 150
>gi|155722990 solute carrier family 4 (anion exchanger), member 1,
adaptor protein [Homo sapiens]
Length = 796
Score = 64.7 bits (156), Expect = 1e-10
Identities = 52/173 (30%), Positives = 76/173 (43%), Gaps = 27/173 (15%)
Query: 246 YSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAV 305
Y EPP + L K +L + S L GR D+ ++HPS S+ HAV
Sbjct: 154 YQEPPWGGPATAPYSLETLKGGTILGTRSLKGTSYCLFGRLSG-CDVCLEHPSVSRYHAV 212
Query: 306 FQYRLVEYTRADGTVGRRVKP-YIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSS 364
Q+R + DG Y+ DLGS +GTFLN RI P+ Y + V++FG S+
Sbjct: 213 LQHRA---SGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFGGST 269
Query: 365 REYVLLHESSDTSE-------------------IDRK---DDEDEEEEEEVSD 395
R ++L D +++K +D DEEEE + S+
Sbjct: 270 RLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSE 322
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 60.5 bits (145), Expect = 3e-09
Identities = 60/222 (27%), Positives = 95/222 (42%), Gaps = 32/222 (14%)
Query: 47 DHSGGSPSPPTSEPARSGHRGN-RARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTV 105
DH G S S ++SG R SRSP K ++++ RS+SP R+RS S
Sbjct: 376 DHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS---RSRSPYKARDRSRSRSPN 432
Query: 106 KVKQ-EREDHPRRGREDRQHREPSE-QEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQ 163
K + R P + R+ + R P++ ++H R+R+ ++ R R S R S ER S G
Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDR--SRSRSPSKERDHSQLGS 490
Query: 164 -GRDRDTQNLQAQEEEREFYNAR----RREHRQRNDVGGGGSESQELVPRPGGNNKEKEV 218
++RD + ++ +ER+ +R R+HR+ Q P NKE++
Sbjct: 491 PSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP-----NKERDR 545
Query: 219 PAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWR 260
PS E + S P ++RWR
Sbjct: 546 SQSRSPSEEREH--------------RQSRSPSKERDRRRWR 573
Score = 58.5 bits (140), Expect = 1e-08
Identities = 55/221 (24%), Positives = 90/221 (40%), Gaps = 25/221 (11%)
Query: 69 RARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQERE-DHPRRGREDRQHREP 127
R R SRSP K ++ + RS+SP R+RS S K + + P + R+ R+ R P
Sbjct: 447 RDRSRSRSPNKARDHS---RSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSP 503
Query: 128 S-EQEHRRARNSDRDRHRGHSHQRRTSNERP-GSGQGQGRDRDTQNLQAQEEEREFYNAR 185
S E++ R++R+S ++ R H R S ER + ++RD ++ EERE +R
Sbjct: 504 SKERQCRQSRSSSKE--RDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561
Query: 186 ----------------RREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELS 229
RE RQ S+ P +KEK
Sbjct: 562 SPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
Query: 230 GALLEDTNTFRGVVIKYSEPPEARIPKK-RWRLYPFKNDEV 269
E ++ K S+P ++ +P+ W+ P + +
Sbjct: 622 TPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSL 662
Score = 52.0 bits (123), Expect = 9e-07
Identities = 46/152 (30%), Positives = 64/152 (42%), Gaps = 12/152 (7%)
Query: 45 RPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSK---SPRSKRNRSPH 101
RP S SP S +R R S S + ++A R K S + ++S
Sbjct: 277 RPQSHSQSRSPRRSRSGSQKRTHSRVR--SHSWKRNHSRARSRTRKGILSQMGRHSQSRS 334
Query: 102 HSTVKVKQEREDHPRRGREDRQHREPS-EQEHRRARNSDRDR-HRGHSHQR----RTSNE 155
HS K Q + PRRGR R PS E+ H +R+S ++R HRG S R R+ +
Sbjct: 335 HSKGK-SQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSG 393
Query: 156 RPGSGQGQGRDRDTQNLQAQEEEREFYNARRR 187
P + R R + + R Y AR R
Sbjct: 394 SPNKQRDHSRSRSPNKARDRSRSRSPYKARDR 425
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/188 (28%), Positives = 73/188 (38%), Gaps = 26/188 (13%)
Query: 41 PAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRS-KRNRS 99
P R SPS R SRSP K++ R S R +R+RS
Sbjct: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS 526
Query: 100 PHHSTVKVKQEREDH-PRRGREDRQHREPSEQ-EHRRAR--NSDRDRHRGHS-------H 148
P K +Q R+ P + R+ Q R PSE+ EHR++R + +RDR R S
Sbjct: 527 PS----KERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR 582
Query: 149 QRRTSNER--------PGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGS 200
Q R+S+E P G R R + +A R ++ H Q
Sbjct: 583 QSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRT--PSKEGNHSQSRTSSKESD 640
Query: 201 ESQELVPR 208
SQ VPR
Sbjct: 641 PSQSTVPR 648
Score = 45.8 bits (107), Expect = 7e-05
Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 16/164 (9%)
Query: 74 SRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPS--EQE 131
SRS K K++ +S++PR R RS + S K+ H R ++R HR S +E
Sbjct: 332 SRSHSKGKSQ---NQSRTPR--RGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKE 386
Query: 132 HRRARNSDRDRHRGHSHQR-------RTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNA 184
R+++ ++ R HS R R+ + P + + R R + R Y A
Sbjct: 387 SGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKA 446
Query: 185 RRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFEL 228
R R + + S S+ P + P+KE+ +L
Sbjct: 447 RDRSRSRSPNKARDHSRSRS--PNKARDRSRSRSPSKERDHSQL 488
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 11/129 (8%)
Query: 31 QERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSK 90
+ER + + R SPS R R SRSP +++ R+S+
Sbjct: 505 KERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH---RQSR 561
Query: 91 SPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQH---REPSEQE-HRRARNSDRDRHRGH 146
SP +R+R S K ++ R+ R E+R H R P++Q + R R S ++ + H
Sbjct: 562 SPSKERDRRRWRSPSKERERRQS--RSSSEERDHSRSRSPNKQSGYSRPRASSKE--KAH 617
Query: 147 SHQRRTSNE 155
S R S E
Sbjct: 618 SRSRTPSKE 626
Score = 39.3 bits (90), Expect = 0.006
Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 11/180 (6%)
Query: 48 HSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKV 107
HS G + P R R+ SR+P K+++ + R S R R S +
Sbjct: 335 HSKGKSQNQSRTPRRG-----RSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK--ES 387
Query: 108 KQEREDHPRRGREDRQHREPSEQEHRRARNSD---RDRHRGHSHQRRTSNERPGSG-QGQ 163
+ + P + R+ + R P++ R S RDR R S + R S + +
Sbjct: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
Query: 164 GRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEK 223
R R +A++ R + R+ + SQ P +++ P+KE+
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
Score = 37.4 bits (85), Expect = 0.024
Identities = 53/232 (22%), Positives = 82/232 (35%), Gaps = 45/232 (19%)
Query: 30 KQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNK----AS 85
+ + S +AP P P PP S + NR+ V P +N +S
Sbjct: 6 RSSKPSMSLAPSGSSMPT---ADPKPPASLKSTKSATPNRSL-VPTKPATSRNSVMSPSS 61
Query: 86 GRRSKSPRSKR---NRSPHHSTVKVK-------------------------QEREDHPRR 117
+ +KS +KR NR S V+ K Q R H R
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
Query: 118 GREDRQHREPSEQEHRRARNSDRDRHRG-----HSHQRRTSNERPGS-GQGQGRDRDTQN 171
R+ S++ RA R R G S R ++++ GS G+ GR R +
Sbjct: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
Query: 172 LQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEK 223
++ + R N ++ +R G G S + P +P+KEK
Sbjct: 182 ERSDSQPR---NLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEK 230
Score = 33.9 bits (76), Expect = 0.26
Identities = 44/173 (25%), Positives = 66/173 (38%), Gaps = 43/173 (24%)
Query: 52 SPSPPTSEPARS-GHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQE 110
+PSP +S +S G +R S SP + ++ +S + S R+R HS Q
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRV---KSYNQASTRSRPQSHS-----QS 284
Query: 111 REDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQ 170
R PRR R Q R S R R HS +R S
Sbjct: 285 RS--PRRSRSGSQKRTHS-------------RVRSHSWKRNHS----------------- 312
Query: 171 NLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEK 223
+A+ R+ ++ H Q G S++Q PR G ++ P+KE+
Sbjct: 313 --RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER 363
Score = 30.4 bits (67), Expect = 2.9
Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 13/101 (12%)
Query: 30 KQERLSPEVAPPAHRR-PDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRR 88
+Q R S E + R P+ G P S ++ R SR+P K+ G
Sbjct: 582 RQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSR-------SRTPSKE-----GNH 629
Query: 89 SKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSE 129
S+S S + P STV + + P R Q+R PS+
Sbjct: 630 SQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSK 670
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 59.7 bits (143), Expect = 4e-09
Identities = 53/179 (29%), Positives = 77/179 (43%), Gaps = 7/179 (3%)
Query: 61 ARSGHRGNRARGVSRSPPKKKNK-ASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGR 119
A G G+R+R SRSP K++K RRS+S R R S K + D R R
Sbjct: 13 ASRGRSGSRSR--SRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRR 70
Query: 120 EDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPG--SGQGQGRDRDTQNLQAQEE 177
+ R+ S +E RR+R+ DR R R S RR+ + PG S + + R R + E
Sbjct: 71 SRSRERDRS-RERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGES 129
Query: 178 EREFYNAR-RREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLED 235
+E + +E + D G E R EK + K + E G L ++
Sbjct: 130 SKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKE 188
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/184 (25%), Positives = 76/184 (41%), Gaps = 28/184 (15%)
Query: 83 KASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDR 142
K S R +S R+RSP + +RG +DR+ R +++ RR R+ RD+
Sbjct: 10 KRSASRGRSGSRSRSRSP----------SDKRSKRG-DDRRSRS-RDRDRRRERSRSRDK 57
Query: 143 HRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSES 202
R S R+ R + + RDR + +++ +R +R R R R+ G S+
Sbjct: 58 RRSRSRDRK----RLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKK 113
Query: 203 QELVPRP------GGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPK 256
E R G ++KEK+ +K + A D N + K E E
Sbjct: 114 TENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVE----- 168
Query: 257 KRWR 260
+WR
Sbjct: 169 -KWR 171
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/155 (24%), Positives = 63/155 (40%), Gaps = 9/155 (5%)
Query: 67 GNRARGVSRSPPKKKNKASGRRSKSPRSKRN-RSPHHSTVKVKQEREDHPRRGREDRQHR 125
G +R + + S RS+SP KR+ R + ++R R R+ R+ R
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 126 EPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNAR 185
+ RR+R+ +RDR S +RR S R + + R R ++ + +
Sbjct: 62 SRDRKRLRRSRSRERDR----SRERRRSRSR-DRRRSRSRSRGRRSRSSSPGNKSKKTEN 116
Query: 186 RREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPA 220
R +++ D GG S+E EKE A
Sbjct: 117 RSRSKEKTD---GGESSKEKKKDKDDKEDEKEKDA 148
Score = 34.3 bits (77), Expect = 0.20
Identities = 31/175 (17%), Positives = 66/175 (37%), Gaps = 40/175 (22%)
Query: 69 RARGVSRSPPKKKNKASGRRSKS--PRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHRE 126
R R SR + ++++ GRRS+S P +K ++ + S K K + + + ++D+ +E
Sbjct: 82 RRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKE 141
Query: 127 PSEQ------------EHRRARNSDRDRHRGHSHQRRTSN-------------------- 154
++ E R R ++ R ++ N
Sbjct: 142 DEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLE 201
Query: 155 ------ERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQ 203
+ P + +G + + + L + E ++ R+ GGGG+E +
Sbjct: 202 DDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKK 256
Score = 33.9 bits (76), Expect = 0.26
Identities = 38/208 (18%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 52 SPSPPTSEPARSGHRGNRARGV------SRSPPKKKNKASGR------RSKSPRSKRNRS 99
S SP R R +R+R SRS K+++++ R RS+ R R
Sbjct: 24 SRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERR 83
Query: 100 PHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGS 159
S + + RR R + + E+R D +++ +++
Sbjct: 84 RSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDE 143
Query: 160 GQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGG-------N 212
+ + D L+ + +R+ + RE +++ + G +E+ G +
Sbjct: 144 KEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDD 203
Query: 213 NKEKEVPAK-EKPSFELSGALLEDTNTF 239
+ +++ PA+ EK E+ G L+ + +
Sbjct: 204 DDDEDDPAEAEKEGNEMEGEELDPLDAY 231
Score = 33.5 bits (75), Expect = 0.34
Identities = 32/147 (21%), Positives = 67/147 (45%), Gaps = 13/147 (8%)
Query: 44 RRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSK----RNRS 99
RR + S + R R +R+R RS ++++++ RR RS+ R+ S
Sbjct: 47 RRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSS 106
Query: 100 PHHSTVKVK-----QEREDHPRRGREDRQHREPSEQEHRR-ARNSDRDRHRGHSHQRRTS 153
P + + K + +E+ D +E ++ ++ E E + A N D+++ +R+
Sbjct: 107 PGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRK-- 164
Query: 154 NERPGSGQGQGRDRDTQNLQAQEEERE 180
ER + + R + +N+ ++E E
Sbjct: 165 -ERVEKWREEQRKKAMENIGELKKEIE 190
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 59.7 bits (143), Expect = 4e-09
Identities = 51/171 (29%), Positives = 83/171 (48%), Gaps = 22/171 (12%)
Query: 30 KQERLSPE-VAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGR- 87
+++ L+PE +P ++ + S S SP S+ H +R+R SR K+K+ GR
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASK-----HHYSRSRSRSRER-KRKSDNEGRK 60
Query: 88 ---RSKSPRSKRNRSPHHSTVKVKQE----REDHPRRGREDRQHREPSEQEHRRARNSDR 140
RS+S +R+ S S+ K K E +E +GRE E E H+R +R
Sbjct: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR---KER 117
Query: 141 DRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQ 191
RG SH R S ER + + R R+ + +++ ER+ +R RE ++
Sbjct: 118 KSSRGRSHSRSRSRER----RHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
Score = 58.2 bits (139), Expect = 1e-08
Identities = 47/163 (28%), Positives = 81/163 (49%), Gaps = 10/163 (6%)
Query: 30 KQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRS 89
K+E+ V+P A + H S S +S + G + R SRS +++++ + S
Sbjct: 23 KKEQSEVSVSPRASKH--HYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSS 80
Query: 90 KSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQ 149
K +S+ + HS+ K +ER + G EDR R+ E++ R R+ R R R H+
Sbjct: 81 KKHKSEEHNDKEHSSDK-GRERLNSSENG-EDRHKRK--ERKSSRGRSHSRSRSRERRHR 136
Query: 150 RRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQR 192
R S ER S + R R+ + +++ ER+ +R RE ++R
Sbjct: 137 SR-SRERKKS---RSRSRERKKSRSRSRERKKSRSRSRERKRR 175
Score = 42.4 bits (98), Expect = 7e-04
Identities = 44/167 (26%), Positives = 70/167 (41%), Gaps = 18/167 (10%)
Query: 7 ERERGSR---RRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSG--GSPSPPTSEPA 61
ER+R S R+HR +++ S + H +HS G +SE
Sbjct: 49 ERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG 108
Query: 62 RSGH-RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRE 120
H R R RS + +++ RS+S K++RS +ER+ R RE
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSR-------SRERKKSRSRSRE 161
Query: 121 DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDR 167
++ R S + RR R+ R R R H H+ R+ + + + RDR
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSR-HRHRTRSRSRT----RSRSRDR 203
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/165 (29%), Positives = 67/165 (40%), Gaps = 16/165 (9%)
Query: 31 QERL-SPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRS 89
+ERL S E H+R + S +RS R R R SRS +KK+++ R
Sbjct: 99 RERLNSSENGEDRHKRKERK----SSRGRSHSRSRSRERRHR--SRSRERKKSRSRSRER 152
Query: 90 KSPRSK-RNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSH 148
K RS+ R R S + ++ R R R +HR S R R+ RDR +
Sbjct: 153 KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS---RTRSRSRDRKKRIEK 209
Query: 149 QRRTSNE-----RPGSGQGQGRDRDTQNLQAQEEEREFYNARRRE 188
RR S P +G+ D Q A+ ER +RE
Sbjct: 210 PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 254
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 58.2 bits (139), Expect = 1e-08
Identities = 40/166 (24%), Positives = 80/166 (48%), Gaps = 7/166 (4%)
Query: 43 HRRPDHSGGSPSPPTSEPARSGHR-GNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPH 101
H R S S + +RS R G+R+R SRS + ++++ +S+SP +++RS
Sbjct: 200 HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRS 259
Query: 102 HSTVKVKQEREDHPRRGREDRQHREPSEQEHRR--ARNSDRDRHRGHSHQRRTSNERPGS 159
HS K + + +D + E Q+ + + R +R+ + + R S +RR E+ GS
Sbjct: 260 HSAGKSRSKSKD---QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS 316
Query: 160 -GQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQE 204
+G+ +++ + +++ + +R R + D G S+E
Sbjct: 317 VSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Score = 49.7 bits (117), Expect = 5e-06
Identities = 49/182 (26%), Positives = 75/182 (41%), Gaps = 16/182 (8%)
Query: 38 VAPPAHRRPD-HSGGSPSPPTSEPAR--SGHRGNRARGVSRSPPKKKNKASGRRSKSPRS 94
V P R P H S S S+ R RG+ +RG S+ +K + S RS+S
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQ---EKSLRQSRSRSRSKGG 339
Query: 95 KRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSN 154
R+RS S K K R+GR ++ RE S R S+R R RG + +
Sbjct: 340 SRSRSRSRSKSKDK-------RKGR--KRSREESRSRSRSRSKSERSRKRGSKRDSKAGS 390
Query: 155 ERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNK 214
+ + R + ++ +ERE + + R + G+ +QE R N+K
Sbjct: 391 SKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT-NQETRSRSRSNSK 449
Query: 215 EK 216
K
Sbjct: 450 SK 451
Score = 47.8 bits (112), Expect = 2e-05
Identities = 40/152 (26%), Positives = 65/152 (42%), Gaps = 3/152 (1%)
Query: 56 PTSEPARSGHRG-NRARGVSRSPPKKKNKASGRRSKSPRSK-RNRSPHHSTVKVKQERED 113
P S RS R + +R SRS +K+++ SKS SK R+RS S + K
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 114 HPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQ 173
R + + R PS+ E R+R+ + R S + + G+ + R +
Sbjct: 237 QSRSRSKKEKSRSPSK-EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK 295
Query: 174 AQEEEREFYNARRREHRQRNDVGGGGSESQEL 205
++ + R RR E +R V G S+ + L
Sbjct: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSL 327
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 4/145 (2%)
Query: 30 KQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHR---GNRARGVSRSPPKKKNKASG 86
K S E +R S G + +RS R G+R+R SRS K K K
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGR- 357
Query: 87 RRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGH 146
+RS+ R+RS S K+ + + G ++ +E +++ R+ + + R H
Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417
Query: 147 SHQRRTSNERPGSGQGQGRDRDTQN 171
+ + E G + G +++T++
Sbjct: 418 AKSESSQREGRGESENAGTNQETRS 442
Score = 43.5 bits (101), Expect = 3e-04
Identities = 40/192 (20%), Positives = 70/192 (36%), Gaps = 4/192 (2%)
Query: 12 SRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRAR 71
SR R ++ V V + R + + R GGS S S R R R
Sbjct: 300 SRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
Query: 72 GVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQE 131
S + ++++ RS+ SKR+ S K+++ED R E+E
Sbjct: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSK---KKKKEDTDRSQSRSPSRSVSKERE 416
Query: 132 HRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQ 191
H ++ +S R+ RG S T+ E + + + +++ + R R +
Sbjct: 417 HAKSESSQRE-GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSR 475
Query: 192 RNDVGGGGSESQ 203
S S+
Sbjct: 476 SRSASRSPSRSR 487
Score = 42.7 bits (99), Expect = 6e-04
Identities = 33/152 (21%), Positives = 66/152 (43%), Gaps = 9/152 (5%)
Query: 56 PTSEPARS-GHRGNRARGVSRSPPKKK--NKASGRRSKSPRSKRNRSPHHSTVKVKQERE 112
P+ E +RS H ++R S+ ++K N + + KS R++S S + ++ R
Sbjct: 250 PSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRV 309
Query: 113 DHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNL 172
+ +RG R + R+R+ + R S R S ++ +GR R +
Sbjct: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK-----RKGRKRSREES 364
Query: 173 QAQEEEREFYNARRREHRQRNDVGGGGSESQE 204
+++ R + R R+ + D G S+ ++
Sbjct: 365 RSRSRSRS-KSERSRKRGSKRDSKAGSSKKKK 395
Score = 33.5 bits (75), Expect = 0.34
Identities = 28/119 (23%), Positives = 45/119 (37%), Gaps = 5/119 (4%)
Query: 112 EDHPRRGREDRQHREPSEQEHR-RARNSDRDRHRG----HSHQRRTSNERPGSGQGQGRD 166
ED P R R S R R+R+S + R R SH + S R GS
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 167 RDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPS 225
+Q+ ++E+ ++ + + + G S+S++ NN P PS
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS 292
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 57.8 bits (138), Expect = 2e-08
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 17/193 (8%)
Query: 69 RARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPS 128
R R R K++ + R+++ R + ++ + ++ERE R R+ + RE
Sbjct: 329 RQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER 388
Query: 129 EQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRRE 188
E+ DRDR R +R+T +R G R+T+ + +E++RE R R
Sbjct: 389 ER--------DRDRDRQKERERQTEKDRDG-------QRETEKQREREKDRESERGRERG 433
Query: 189 HRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTN-TFRGVVIKYS 247
+ G ++ + G K + P SG + D N RG+ K S
Sbjct: 434 REREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSS 493
Query: 248 -EPPEARIPKKRW 259
E P+A + W
Sbjct: 494 PEDPKAASTRFPW 506
Score = 56.2 bits (134), Expect = 5e-08
Identities = 31/126 (24%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
Query: 69 RARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPS 128
R R R +K+ + R + R++R+R + ++ + R + +R+
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER 325
Query: 129 EQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQ-GQGRDRDTQNLQAQEEEREFYNARRR 187
E+E +R DR++ R +R+T +R + Q G+ R + + +E ER+ +AR R
Sbjct: 326 ERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARER 385
Query: 188 EHRQRN 193
E R+R+
Sbjct: 386 EERERD 391
Score = 55.5 bits (132), Expect = 8e-08
Identities = 45/196 (22%), Positives = 76/196 (38%), Gaps = 15/196 (7%)
Query: 69 RARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPS 128
R G + ++ R+ + R + R T + ++ R + R + DR
Sbjct: 40 RGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQR 99
Query: 129 EQEHRRARNSD--RDRHRGHSHQRRTSNERPGSGQGQ-GRDRDTQNLQAQEEEREFYNAR 185
++E R R +D RDR R R+ ER +G+ GRDR T + +E +R+ R
Sbjct: 100 DREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKER 159
Query: 186 RRE---HRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGV 242
R+ RQR E + R +E++ + K ED ++ RG
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK---------TEDRHSERGR 210
Query: 243 VIKYSEPPEARIPKKR 258
+ E +KR
Sbjct: 211 ERERERETETETERKR 226
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/233 (21%), Positives = 87/233 (37%), Gaps = 16/233 (6%)
Query: 2 KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPA 61
+ + E ERG R R DG ++ + R+ D + +
Sbjct: 129 RETEREGERG-RDRQTDGQ---------RERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 62 RSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSK-RNRSPHHSTVKVKQEREDHPRRGRE 120
R + + R +K+NK R S+ R + R R T + +Q + R+ +
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 121 DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE 180
+R+ + +E+E R ++RD+ R R +R + + DR Q ++ E E
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Query: 181 FYNARRRE-----HRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFEL 228
R+RE R R E + R ++EKE K K E+
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM 351
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Query: 88 RSKSPRSKRNRSPHHSTVKVKQ-EREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGH 146
R + +++R R+ T + K+ ERE R R+ RQ + + +R R ++RDR
Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299
Query: 147 SHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRRE-HRQRNDVGGGGSESQEL 205
+R+ ER + + R+R+ + + +E +RE R +E R+R E
Sbjct: 300 KRERQRERERERE-RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 206 VPRPGGNNKEKE 217
R G E+E
Sbjct: 359 TGREGRRQAERE 370
Score = 45.8 bits (107), Expect = 7e-05
Identities = 46/212 (21%), Positives = 83/212 (39%), Gaps = 18/212 (8%)
Query: 7 ERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHR 66
ER R R+ R+ D K+ER + HR+ D E R R
Sbjct: 63 ERRREKRQTERETDR--------KRERRREK---DRHRKRDRHRERQRDREKERERQTDR 111
Query: 67 G-NRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHR 125
+R R R+ K++ + + R + R ++ + E+E + RE ++
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
Query: 126 EPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNAR 185
E + Q+ R R +R R QR N+ +GR+R+ + E ER+ R
Sbjct: 172 ERNRQKERE-REKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDR 230
Query: 186 RREHRQRNDVGGGGSESQELVPRPGGNNKEKE 217
R+ +++ + E ++ R + +E E
Sbjct: 231 ERDRQRKTE-----REREKQAERERASERETE 257
Score = 45.4 bits (106), Expect = 9e-05
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 59 EPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRG 118
E R R R + R +K+ + + R ++ R + + + ++RE R
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERE 324
Query: 119 REDRQHREPS-----EQEHRRARNS--DRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQN 171
RE + RE E+E +R R + DR+R+R + R ER + + R+RD Q+
Sbjct: 325 RERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERE---RERERERDRQS 381
Query: 172 LQAQEE-EREFYNARRREHRQRNDVGGGGSESQE 204
+ +EE ER+ R++E ++ + G E
Sbjct: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETE 415
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/108 (21%), Positives = 44/108 (40%), Gaps = 3/108 (2%)
Query: 62 RSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRED 121
++G G R R +++++ S R + R+R + ++ D R +
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 122 RQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDT 169
R+ + E E R R +R++ +G R +R G+ R R T
Sbjct: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQA---GRQRKRST 462
Score = 35.8 bits (81), Expect = 0.069
Identities = 40/162 (24%), Positives = 55/162 (33%), Gaps = 9/162 (5%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARS- 63
+S RER R R RD D K+ E R + SE R
Sbjct: 380 QSAREREERERDRDRDRQ-------KERERQTEKDRDGQRETEKQREREKDRESERGRER 432
Query: 64 GHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRG-REDR 122
G + +G R ++ ++ +GR+ K N P + V Q + P RG R
Sbjct: 433 GREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKS 492
Query: 123 QHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQG 164
+P R RG RR R G +GQG
Sbjct: 493 SPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQG 534
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 57.0 bits (136), Expect = 3e-08
Identities = 66/286 (23%), Positives = 103/286 (36%), Gaps = 29/286 (10%)
Query: 34 LSPEVAPPAHRRPDH--SGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKS 91
LSP +P R H G S E R R R +++ S R
Sbjct: 267 LSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLE 326
Query: 92 PRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRR 151
R R+R H S + + + D RR R DR+ + +E+ RR R+ D++R +R
Sbjct: 327 RRRSRSRERHRSRSRSRDRKGD--RRDR-DREREKENERGRRRDRDYDKERGNEREKERE 383
Query: 152 TSNERPGSGQGQG--------------RDRDTQNLQAQEEEREFYNARRREHRQRNDVGG 197
S ER + +G R RD + +E++ +R R+HR R+
Sbjct: 384 RSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRN 443
Query: 198 GGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKK 257
G S+ +K + K S SG+ + + ++S E +
Sbjct: 444 AGKRSRSRSKEKSSKHKNESKEKSNKRS--RSGSQGRTDSVEKSKKREHSPSKEKSRKRS 501
Query: 258 RWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQH 303
R + K D H S +H R I+ S KQH
Sbjct: 502 RSKERSHKRD--------HSDSKDQSDKHDRRRSQSIEQESQEKQH 539
Score = 54.7 bits (130), Expect = 1e-07
Identities = 53/230 (23%), Positives = 86/230 (37%), Gaps = 15/230 (6%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSG 64
+S R SR HR+G +++E+ + A R S S R
Sbjct: 271 RSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRS 330
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVK-----QEREDHPRRGR 119
R R SRS +K ++ R + ++R R K + +ERE R +
Sbjct: 331 RSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK 390
Query: 120 EDRQHREPSEQEH------RRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQ 173
E R E E++H RR R+ RD + H R S ER + + R+ ++
Sbjct: 391 EQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRS 450
Query: 174 AQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEK 223
+E+ + +E + G SQ + K + P+KEK
Sbjct: 451 RSKEKSSKHKNESKEKSNKRSRSG----SQGRTDSVEKSKKREHSPSKEK 496
Score = 53.1 bits (126), Expect = 4e-07
Identities = 46/165 (27%), Positives = 64/165 (38%), Gaps = 16/165 (9%)
Query: 32 ERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHR-GNRARGVSRSPPKKKNKASGRRSK 90
E + V R P S P +RS HR G+ + R ++K + R
Sbjct: 249 EEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREA 308
Query: 91 SPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQR 150
R K R +R RR R +HR S R+ DRDR +R
Sbjct: 309 KEREKERRRSR------SIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR------ER 356
Query: 151 RTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDV 195
NER G+ + RD D + +E+ERE R +E R R +V
Sbjct: 357 EKENER---GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEV 398
Score = 47.8 bits (112), Expect = 2e-05
Identities = 54/203 (26%), Positives = 85/203 (41%), Gaps = 42/203 (20%)
Query: 5 KSERERGSRRRHRDGDVVLP---------AGVVVKQERLSPEVAPPAH-------RRPDH 48
+ E ERG RRR RD D + K++R EV H R D
Sbjct: 357 EKENERG-RRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDD 415
Query: 49 SGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVK 108
S +RS R +R+R SR+ +G+RS+S RSK S H + K K
Sbjct: 416 KRDSKKEKKHSRSRSRERKHRSRSRSRN--------AGKRSRS-RSKEKSSKHKNESKEK 466
Query: 109 -QEREDHPRRGRED-------RQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSG 160
+R +GR D R+H E+ +R+R+ +R R HS + S++
Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHD--- 523
Query: 161 QGQGRDRDTQNLQAQEEEREFYN 183
R +Q+++ + +E++ N
Sbjct: 524 -----RRRSQSIEQESQEKQHKN 541
Score = 33.5 bits (75), Expect = 0.34
Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 2 KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPA 61
K K R R R+HR AG K+ R + H+ +++ +
Sbjct: 421 KEKKHSRSRSRERKHRSRSRSRNAG---KRSRSRSKEKSSKHKNESKE------KSNKRS 471
Query: 62 RSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSK-RNRSPHHSTVKVKQEREDHPR---- 116
RSG +G R V +S ++ + + + K RSK R+ HS K + ++ D R
Sbjct: 472 RSGSQG-RTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSI 530
Query: 117 -RGREDRQHREPSE 129
+ +++QH+ E
Sbjct: 531 EQESQEKQHKNKDE 544
Score = 31.6 bits (70), Expect = 1.3
Identities = 35/164 (21%), Positives = 61/164 (37%), Gaps = 21/164 (12%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSG 64
K +E RRHRD + K R R + G S S+ S
Sbjct: 401 KKHKEDKDDRRHRDDK--RDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSK 458
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQH 124
H+ +S + ++ + GR +SK+ RE P + + R+
Sbjct: 459 HKNESKE---KSNKRSRSGSQGRTDSVEKSKK--------------REHSPSK-EKSRKR 500
Query: 125 REPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRD 168
E+ H+R + +D+ H +R S E+ S + Q +++D
Sbjct: 501 SRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQE-SQEKQHKNKD 543
>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo
sapiens]
Length = 1554
Score = 57.0 bits (136), Expect = 3e-08
Identities = 35/94 (37%), Positives = 48/94 (51%), Gaps = 11/94 (11%)
Query: 276 HRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGN 335
HR L+ R ++ + S KQHAV Y R + ++ DLGS N
Sbjct: 16 HRLPRELIFVGREECELMLQSRSVDKQHAVINYDQ-----------DRDEHWVKDLGSLN 64
Query: 336 GTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVL 369
GTF+N+ RI Q+Y LK DV++FG+ S YVL
Sbjct: 65 GTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVL 98
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 53.9 bits (128), Expect = 2e-07
Identities = 45/185 (24%), Positives = 68/185 (36%), Gaps = 11/185 (5%)
Query: 40 PPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRS 99
P R P+ + +S R G R R P + GR + R +R
Sbjct: 603 PERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREE 662
Query: 100 PHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGS 159
V +R D R R DR+ E+E R R DR+R + +R + ER
Sbjct: 663 RRVDRV---DDRRDERARER-DRERERDRERERERERERDREREKERELERERARERERE 718
Query: 160 GQGQ-------GRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGN 212
+ + RD D + + +E +RE R RE R+R E + R
Sbjct: 719 REKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERAR 778
Query: 213 NKEKE 217
++KE
Sbjct: 779 ERDKE 783
Score = 50.1 bits (118), Expect = 4e-06
Identities = 34/149 (22%), Positives = 60/149 (40%), Gaps = 7/149 (4%)
Query: 53 PSPPTSEPARSGH----RGNRARGVSRSPPKKKNKASGR---RSKSPRSKRNRSPHHSTV 105
PS P R+ R V R ++ +A R R + +R R
Sbjct: 641 PSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRE 700
Query: 106 KVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGR 165
+ K+ + R +R+ + ++E R R+ DR+R R R ER + + R
Sbjct: 701 REKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERER 760
Query: 166 DRDTQNLQAQEEEREFYNARRREHRQRND 194
+R+ + + +E ERE R +E ++ D
Sbjct: 761 ERERERERERERERERARERDKERERQRD 789
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/165 (23%), Positives = 65/165 (39%), Gaps = 5/165 (3%)
Query: 31 QERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSK 90
Q L+P + A P HS SP S P HR + R R ++ +++ RR +
Sbjct: 360 QRTLTPPLRRSASPYPSHSLSSPQRKQSPPR---HR-SPMREKGRHDHERTSQSHDRRHE 415
Query: 91 SPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHR-GHSHQ 149
R + + ++E E R+ R REP + RR RDR S
Sbjct: 416 RREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRD 475
Query: 150 RRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRND 194
R S E + RD ++ ++ + ++ + R+ ++ D
Sbjct: 476 MRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKED 520
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/147 (23%), Positives = 66/147 (44%), Gaps = 11/147 (7%)
Query: 68 NRARGVSRSPPKKKNKASGRRSKSPRSK-RNRSPHHSTVKVKQEREDHPRRGREDRQHRE 126
+R R R +++ + R + R + R+R H + ++ D + +R+ RE
Sbjct: 698 DREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERE 757
Query: 127 PSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQE-----EEREF 181
E+E R R +R+R R + +R ER + + + RD + + +E R+
Sbjct: 758 -RERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG 816
Query: 182 YNARRREHRQRNDVGGGGSESQELVPR 208
++ R+ + R RN+ GS S P+
Sbjct: 817 HDERKSKKRYRNE----GSPSPRQSPK 839
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 18/151 (11%)
Query: 44 RRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHS 103
+R HSG T +G R +R + R P + + + S+S S+R+ SP
Sbjct: 1225 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRS-SP--- 1280
Query: 104 TVKVKQEREDHPRRGREDRQHR--EPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQ 161
+ +R+ H R G D + R E EH R R +R R R + P
Sbjct: 1281 ----ESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWP---- 1332
Query: 162 GQGRDRDTQNLQAQEEEREFYNARRREHRQR 192
R+RD L+ +E ERE + RR R+R
Sbjct: 1333 ---RNRDRDRLRERERERE-RDKRRDLDRER 1359
Score = 45.4 bits (106), Expect = 9e-05
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Query: 52 SPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQER 111
+PSP R + + S S + K S R +SP ++ R H T + R
Sbjct: 354 TPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRR 413
Query: 112 ED--HPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRD-RD 168
+ RG+ DR+ E+E+ + ++S RD HR R + R R+ RD
Sbjct: 414 HERREDTRGKRDREKDSREEREYEQDQSSSRD-HRDDREPRDGRDRRDARDTRDRRELRD 472
Query: 169 TQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKE 217
+++++ E R+ Y+ +E R D ++ + R G + KE
Sbjct: 473 SRDMRDSREMRD-YSRDTKESRDPRD-SRSTRDAHDYRDREGRDTHRKE 519
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/194 (25%), Positives = 71/194 (36%), Gaps = 28/194 (14%)
Query: 39 APPAHRRP-------DHSGGSPSPPTSEPARSGHRGNRARGV-SRSPPKKKNKASGRRS- 89
+PP HR P DH S S R RG R R SR + + S R
Sbjct: 387 SPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDH 446
Query: 90 ---KSPRSKRNRSPHHSTVKVKQEREDHPRR--------GREDRQHREPSEQEHRRARNS 138
+ PR R+R T ++ R+ R R+ ++ R+P + R +
Sbjct: 447 RDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHD 506
Query: 139 DRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQ--RNDVG 196
RDR +H R + P + GR+ +L+ + E N R E R RND
Sbjct: 507 YRDREGRDTH--RKEDTYPEESRSYGRN----HLREESSRTEIRNESRNESRSEIRNDRM 560
Query: 197 GGGSESQELVPRPG 210
G +P G
Sbjct: 561 GRSRGRVPELPEKG 574
Score = 42.7 bits (99), Expect = 6e-04
Identities = 43/189 (22%), Positives = 72/189 (38%), Gaps = 17/189 (8%)
Query: 43 HRRPDHSGGSPSPPTSEPARSGHRGNR-ARGVSRSPPKKKNKASGRRSKSPRSKRNRSPH 101
H R + S + +RS R +R R R P + + G R S + S +
Sbjct: 533 HLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592
Query: 102 HSTVKVKQ---EREDHPRRGREDRQHREPSEQEH---RRARNSDRD-------RHRGHSH 148
H + + + ER+ +P R D+ E+ H R N +RD RH+G +
Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND 652
Query: 149 QRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPR 208
+ R + DR + + ++ ERE R RE + D E + + R
Sbjct: 653 ELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERD---REREKERELER 709
Query: 209 PGGNNKEKE 217
+E+E
Sbjct: 710 ERARERERE 718
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/166 (18%), Positives = 63/166 (37%), Gaps = 6/166 (3%)
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHR 125
R RAR R + + + R + R R + + + R DR+
Sbjct: 672 RDERARERDRERERDRER---ERERERERDREREKERELERERAREREREREKERDRERD 728
Query: 126 EPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNAR 185
+ + R R +RDR + +R + + R+R+ + +A+E ++E R
Sbjct: 729 RDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKE--RER 786
Query: 186 RREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGA 231
+R+ ++ E +E + R N ++ K K + G+
Sbjct: 787 QRDWEDKDKGRDDRREKREEI-REDRNPRDGHDERKSKKRYRNEGS 831
Score = 39.7 bits (91), Expect = 0.005
Identities = 42/185 (22%), Positives = 77/185 (41%), Gaps = 14/185 (7%)
Query: 51 GSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQE 110
GSPSP S R H + S +K++ + + P+ R+ SP H T +
Sbjct: 830 GSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVR-PQESRSLSPSHLTEDRQGR 888
Query: 111 REDHPRRGREDRQHREPSEQEHRRARNS-DRDRHRGHSHQRRTSNERPGSGQGQGRDRDT 169
++ R+ R EQE + +S D+ R + + + G Q DR+T
Sbjct: 889 WKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRET 948
Query: 170 QNLQAQEEEREFYNARRR--EHRQRNDVG-------GGGSESQELVPRPGGNNKEKEVPA 220
+ +A +E ++ +++ + ++ +DVG + Q P+ G K+K +
Sbjct: 949 SD-RAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKG--QKKKSIEK 1005
Query: 221 KEKPS 225
K K S
Sbjct: 1006 KRKKS 1010
Score = 39.3 bits (90), Expect = 0.006
Identities = 58/264 (21%), Positives = 94/264 (35%), Gaps = 30/264 (11%)
Query: 7 ERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRP---DHSGGSPSPPTSEPARS 63
ERER R R R+ + ++ER +R G E R
Sbjct: 750 EREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRE 809
Query: 64 GHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPR------R 117
+S + +N+ S +SP+ +R SP ++ + R R
Sbjct: 810 DRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVR 869
Query: 118 GREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEE 177
+E R E R+ R + DR +R+ S+ R + Q ++ Q E
Sbjct: 870 PQESRSLSPSHLTEDRQGRWKEEDR----KPERKESSRR---YEEQELKEKVSSVDKQRE 922
Query: 178 EREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEK----EVPAKEKPSFELSGALL 233
+ E + R R ++ +G SE +E R NK+K + P K+K
Sbjct: 923 QTEILESSRM--RAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKE-------- 972
Query: 234 EDTNTFRGVVIKYSEPPEARIPKK 257
+D RG + SE + PKK
Sbjct: 973 DDVGIERGNIETTSEDGQVFSPKK 996
Score = 37.4 bits (85), Expect = 0.024
Identities = 44/183 (24%), Positives = 68/183 (37%), Gaps = 27/183 (14%)
Query: 16 HRDGDV------VLPAGVVVKQERLSPEVAPPAHRRPDH-SGGSPSPPTSEPARSGHRGN 68
HR GD VL +G +++ S E+ R D G PS TS R R +
Sbjct: 1215 HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSD-RQDSRSH 1273
Query: 69 RARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQERE------------DHPR 116
+R S ++ + SG R + H + ++ R+ D PR
Sbjct: 1274 SSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPR 1333
Query: 117 RGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQE 176
DR E+E + R+ DR+R R S +R RDR ++ Q +
Sbjct: 1334 NRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDR-------DRDRTFESSQIES 1386
Query: 177 EER 179
+R
Sbjct: 1387 VKR 1389
Score = 33.5 bits (75), Expect = 0.34
Identities = 19/84 (22%), Positives = 35/84 (41%)
Query: 97 NRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNER 156
N H + + E+ + P ED QHR+P +Q+ + S+R S + R+ +
Sbjct: 1153 NEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSND 1212
Query: 157 PGSGQGQGRDRDTQNLQAQEEERE 180
G + + L + +RE
Sbjct: 1213 SAHRSGDDQSGRKRVLHSGSRDRE 1236
Score = 28.9 bits (63), Expect = 8.5
Identities = 48/196 (24%), Positives = 70/196 (35%), Gaps = 32/196 (16%)
Query: 52 SPSPPTSEPARSGHRGNRARGVSRSPPKKKN--KASGRRSKSPRSKRNR----SP---HH 102
SP PP E G + V +K K GR + R KR++ SP HH
Sbjct: 265 SPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHH 324
Query: 103 STVKVK------------QEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQR 150
S + + Q PRR R + + R S H S QR
Sbjct: 325 SPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQR 384
Query: 151 RTSNERPGSG-QGQGR---DRDTQNLQAQEEEREFYNARR------REHRQ-RNDVGGGG 199
+ S R S + +GR +R +Q+ + E RE +R RE R+ D
Sbjct: 385 KQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSR 444
Query: 200 SESQELVPRPGGNNKE 215
+ PR G + ++
Sbjct: 445 DHRDDREPRDGRDRRD 460
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 53.5 bits (127), Expect = 3e-07
Identities = 37/137 (27%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Query: 60 PARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHST-VKVKQEREDHPRRG 118
P+ S HR +R+R RS K +++ RRSKSPR +R+ S + + D +
Sbjct: 261 PSSSRHRRSRSRSRRRSHSKSRSR---RRSKSPRRRRSHSRERGRRSRSTSKTRDKKKED 317
Query: 119 REDRQHREP--SEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQE 176
+E ++ + P S RR+R++ R+R R S S ++P S + + + +E
Sbjct: 318 KEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKE 377
Query: 177 EEREFYNARRREHRQRN 193
++++ R R+ R+R+
Sbjct: 378 KKKDKDKERSRDERERS 394
Score = 49.3 bits (116), Expect = 6e-06
Identities = 55/250 (22%), Positives = 97/250 (38%), Gaps = 61/250 (24%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPAR-- 62
K E+ R SR R R P+ ++ R RR HS + P R
Sbjct: 242 KEEKRRHSRSRSRSRRRRTPSSSRHRRSR-------SRSRRRSHSKSRSRRRSKSPRRRR 294
Query: 63 --SGHRGNRARGVSRSPPKKKNKASGRRSKSP-----------------RSKRNRSPHHS 103
S RG R+R S++ KKK +RSK+P R +R+RS S
Sbjct: 295 SHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRS 354
Query: 104 -----TVKVKQEREDHPRRGRED----------RQHREPSEQEHRRARNSDRDRHRGHSH 148
+ K K R PRR +++ R RE S + +++++ ++DR R
Sbjct: 355 PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE- 413
Query: 149 QRRTSNERPGSGQGQGRDRDTQNL-QAQEEEREFYNARRREHRQRNDVGGGGSESQELVP 207
D+D + + + +EE + Y++ + + ++ + G +++E
Sbjct: 414 ----------------SDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSV 457
Query: 208 RPGGNNKEKE 217
G + +E
Sbjct: 458 EKGTGDSLRE 467
Score = 43.5 bits (101), Expect = 3e-04
Identities = 44/154 (28%), Positives = 63/154 (40%), Gaps = 26/154 (16%)
Query: 77 PPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRAR 136
P KK+ K RS+S RS+R R+P S RR R + R S+ RR
Sbjct: 239 PDKKEEKRRHSRSRS-RSRRRRTPSSS----------RHRRSRSRSRRRSHSKSRSRRRS 287
Query: 137 NSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARR-----REHRQ 191
S R R R HS + R R S + D + +++ + + ARR RE R+
Sbjct: 288 KSPR-RRRSHSRE-RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR 345
Query: 192 RNDVGGGGSESQELVPR--------PGGNNKEKE 217
R G S + P+ P + KEK+
Sbjct: 346 RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK 379
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 53.5 bits (127), Expect = 3e-07
Identities = 54/194 (27%), Positives = 78/194 (40%), Gaps = 22/194 (11%)
Query: 32 ERLSPEVAPPAHRRP-DHSGGSPSPPTSE-PARSGHRGNRARGVSRSPPKKKNKASGRRS 89
ER + +HR P + S SPS P++ HRG R SP K+ +++ RRS
Sbjct: 1667 ERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERR-HHSPSKRSHRSPARRS 1725
Query: 90 -KSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEH-----RRARNSDRDRH 143
+SP + + SP + ER H +R H PSE+ H RR R+ RH
Sbjct: 1726 HRSPSERSHHSPSERSHHSPSERRHH---SPSERSHCSPSERSHCSPSERRHRSPSERRH 1782
Query: 144 RG------HSHQRRT----SNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRN 193
HS R+ S R S + R + ER + + R HR+ +
Sbjct: 1783 HSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRIS 1842
Query: 194 DVGGGGSESQELVP 207
+ SE L P
Sbjct: 1843 ERSHSPSEKSHLSP 1856
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/162 (26%), Positives = 65/162 (40%), Gaps = 14/162 (8%)
Query: 43 HRRP-DHSGGSPSPPT--SEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRS 99
H P + S SPS S P RS H + RG+ + S RR SP + +RS
Sbjct: 1598 HSSPSERSWRSPSQRNHCSPPERSCHSLSE-RGLHSPSQRSHRGPSQRRHHSPSERSHRS 1656
Query: 100 PHHSTVKVKQERE-----DHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSN 154
P + + ER RG +R H PSE+ H R+ + HRG S +R S
Sbjct: 1657 PSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRH---RSPSQRSHRGPSERRHHSP 1713
Query: 155 ERPGSGQGQGRDRDTQNLQAQE--EEREFYNARRREHRQRND 194
+ R + + ++ ER ++ R H ++
Sbjct: 1714 SKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSE 1755
Score = 36.6 bits (83), Expect = 0.041
Identities = 31/146 (21%), Positives = 59/146 (40%), Gaps = 11/146 (7%)
Query: 56 PTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHP 115
P S R+ HR + + K+ N S R ++PR R+ H+ + + + +
Sbjct: 1518 PGSPVKRTWHRHLK----DKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERS 1573
Query: 116 RRGREDRQHREPSEQEH----RRARNSDRDRHRGHSHQRRTSNERPGSGQG---QGRDRD 168
+R +R+H PS++ H R+ +S +R QR + S +G
Sbjct: 1574 QRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSP 1633
Query: 169 TQNLQAQEEEREFYNARRREHRQRND 194
+Q +R ++ R HR ++
Sbjct: 1634 SQRSHRGPSQRRHHSPSERSHRSPSE 1659
Score = 33.1 bits (74), Expect = 0.45
Identities = 38/167 (22%), Positives = 60/167 (35%), Gaps = 23/167 (13%)
Query: 13 RRRHRDGDVVLPAGVVVKQERL---------SPEVAPPAHRRPDHSGGSPSPPTSEPA-- 61
+R R D + PAG +KQE + S + A+ P P S+
Sbjct: 1406 KRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIA 1465
Query: 62 -RSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVK----------VKQE 110
++ G R V + + K R S + +N S + V+ VK+
Sbjct: 1466 FQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRT 1525
Query: 111 REDHPRRGREDRQHREPSEQEHRRARN-SDRDRHRGHSHQRRTSNER 156
H + ++H PS R R S+R RH R+ +ER
Sbjct: 1526 WHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSER 1572
Score = 33.1 bits (74), Expect = 0.45
Identities = 36/146 (24%), Positives = 50/146 (34%), Gaps = 24/146 (16%)
Query: 5 KSERERGSRRRH----RDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEP 60
+S RRRH R +L ER S +HRR SPS
Sbjct: 1796 RSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPS------ 1849
Query: 61 ARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSP------------HHSTVKVK 108
H R ++ + +SG+ SP + +RSP H S+ +
Sbjct: 1850 -EKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERT 1908
Query: 109 QEREDHPRRGR-EDRQHREPSEQEHR 133
+ R GR R H PSE+ R
Sbjct: 1909 RHSPSEMRPGRPSGRNHCSPSERSRR 1934
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 53.5 bits (127), Expect = 3e-07
Identities = 53/202 (26%), Positives = 80/202 (39%), Gaps = 20/202 (9%)
Query: 30 KQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRR- 88
+ R SPE+ A S SP T HR R+ VS P +K+++S RR
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR--RSPSVSSPEPAEKSRSSRRRR 1746
Query: 89 -SKSPR----SKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRH 143
+ SPR S+R RSP +++ R R R ++ ++++ R R
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRS----RSRREKTRTTRRRDRSGSSQSTSRRRQ 1802
Query: 144 RGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQ 203
R S R T R GSG +++ QE R ++RRR R R
Sbjct: 1803 RSRSRSRVTRRRRGGSGY------HSRSPARQESSRT--SSRRRRGRSRTPPTSRKRSRS 1854
Query: 204 ELVPRPGGNNKEKEVPAKEKPS 225
P P ++ + PA + S
Sbjct: 1855 RTSPAPWKRSRSRASPATHRRS 1876
Score = 48.5 bits (114), Expect = 1e-05
Identities = 43/200 (21%), Positives = 71/200 (35%), Gaps = 11/200 (5%)
Query: 35 SPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRS 94
SPEV + P S SP + R+ R S P +A RRS+S S
Sbjct: 1582 SPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641
Query: 95 KRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQ----- 149
+ R P + +HP + R R+ S + ++R R R S +
Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKA 1701
Query: 150 RRTSNERPGSGQGQGRDRD------TQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQ 203
R + R S + R R + ++ + E + ++RRR +
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761
Query: 204 ELVPRPGGNNKEKEVPAKEK 223
P+P G + + +EK
Sbjct: 1762 SPSPKPRGLQRSRSRSRREK 1781
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/192 (26%), Positives = 77/192 (40%), Gaps = 18/192 (9%)
Query: 35 SPEVAPPAHRRPD---HSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKS 91
S E +PP+ + H+ SP P PA HR + S++ + K S +
Sbjct: 417 SSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT 476
Query: 92 PRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRR 151
P + RS +T K + R P + R H + RR+R++ R R S QRR
Sbjct: 477 PSRRMGRSRSPATAKRGRSRSRTPTK----RGHSRSRSPQWRRSRSAQR-WGRSRSPQRR 531
Query: 152 TSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGG 211
+ P G R R+TQ +ARR R+ G S S+ P G
Sbjct: 532 GRSRSP-QRPGWSRSRNTQRRGRSR------SARRGRSHSRSPATRGRSRSR--TPARRG 582
Query: 212 NNKEKEVPAKEK 223
++ + PA+ +
Sbjct: 583 RSRSR-TPARRR 593
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/220 (26%), Positives = 87/220 (39%), Gaps = 38/220 (17%)
Query: 35 SPEVAPPAHR---RPDHSGGS-----PSPPTSEPARSG----HRGNRARGVSRSPPKKKN 82
SPE PA R R SG S PSP S S + AR SRS P+ K
Sbjct: 1621 SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT 1680
Query: 83 KASGRRSKSPRSKRNRSPHHSTVKVKQEREDH------PRRGREDRQHR--------EPS 128
K+ PR + +RS T K + R R R +HR EP+
Sbjct: 1681 KS----RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPA 1736
Query: 129 EQEH--RRARNSDRDRHRGHSHQRRTSNERP-GSGQGQGRDRDTQNLQAQEEEREFYNAR 185
E+ RR R++ R + S + R+ + +P G + + R R + + +R +
Sbjct: 1737 EKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQS 1796
Query: 186 RREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPS 225
RQR+ S S+ R GG+ PA+++ S
Sbjct: 1797 TSRRRQRS-----RSRSRVTRRRRGGSGYHSRSPARQESS 1831
Score = 47.4 bits (111), Expect = 2e-05
Identities = 48/190 (25%), Positives = 75/190 (39%), Gaps = 16/190 (8%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGH 65
+E+ R SRRR P + SP P +R S S E R+
Sbjct: 1736 AEKSRSSRRRRSASS---PRTKTTSRRGRSPSPKPRGLQR------SRSRSRREKTRTTR 1786
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHR 125
R +R+ G S+S +++ + S RS+ R +R S +HS +QE R R R
Sbjct: 1787 RRDRS-GSSQSTSRRRQR-SRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRT 1844
Query: 126 EPSEQEHRRARNSDRDRHRGHSH-----QRRTSNERPGSGQGQGRDRDTQNLQAQEEERE 180
P+ ++ R+R S R S RR+ + P + + R R + + + R
Sbjct: 1845 PPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT 1904
Query: 181 FYNARRREHR 190
RR R
Sbjct: 1905 SVTRRRSRSR 1914
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/167 (25%), Positives = 66/167 (39%), Gaps = 16/167 (9%)
Query: 52 SPSPPTSEPARSGHRGNRARGVSRSPPKKKNK--------------ASGRRSKSPRSKRN 97
S SP T +RS R R SR+P +++++ A RS+S R
Sbjct: 564 SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARR 623
Query: 98 RSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARN-SDRDRHRGHSHQRRTSNER 156
RS S V+ ++ R P R + R P+ + R+R + R R R + RR+ R
Sbjct: 624 RSRTRSPVR-RRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSR 682
Query: 157 PGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQ 203
+ +GR R + + R R R G GS S+
Sbjct: 683 SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSE 729
Score = 42.7 bits (99), Expect = 6e-04
Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 20/135 (14%)
Query: 46 PDHSGGSPSPPTSEPARSGHRGNRARGVSRSPP-----KKKNKASGRRSKSPRSKRNRSP 100
P P EP + + R SRSP KKK K GRRS+S +R R
Sbjct: 153 PQRRAREAKQPAPEPPKP-YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKK 211
Query: 101 HHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRG--------HSHQRRT 152
K + E E + R+HR P+ + R++++ R R R +H+ +
Sbjct: 212 SSKKKKHRSESES------KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTS 265
Query: 153 SNERPGSGQGQGRDR 167
++ S + R R
Sbjct: 266 ADSASSSDTSRSRSR 280
Score = 42.7 bits (99), Expect = 6e-04
Identities = 48/206 (23%), Positives = 79/206 (38%), Gaps = 29/206 (14%)
Query: 42 AHRRPDHSGGSPSPPTSE--------PARSGHRGNRAR-----------GVSRSPPKKKN 82
+H G S SP T++ P + GH +R+ G SRSP ++
Sbjct: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR 533
Query: 83 KASGRRSKSPRSK--RNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDR 140
S +R RS+ + R S + + RGR + R P+ + R+R R
Sbjct: 534 SRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS--RSRTPARRGRSRSRTPAR 591
Query: 141 DRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNAR-----RREHRQRNDV 195
R R + RR S R + +G+ R R +++ +R RR R R+
Sbjct: 592 RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT 651
Query: 196 GGGGSESQELVPRPGGNNKEKEVPAK 221
S+ P G ++ + PA+
Sbjct: 652 PARRGRSRSRTPARRGRSRSR-TPAR 676
Score = 42.4 bits (98), Expect = 7e-04
Identities = 40/161 (24%), Positives = 64/161 (39%), Gaps = 17/161 (10%)
Query: 41 PAHRR-----PDHSGGSPSPPTSEPARSGHRGNRARGVSRS-PPKKKNKASGRRSKSPRS 94
PA RR P P RS R RG SRS P ++ ++ RS++P
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS---RSRTPAR 676
Query: 95 KRNRSPHHSTVKVKQEREDHPRRGRE--------DRQHREPSEQEHRRARNSDRDRHRGH 146
+ RS + + + R PRRGR R H ++ R +S+R
Sbjct: 677 RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT 736
Query: 147 SHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRR 187
S +R SN P + + R +++L + + + + RR
Sbjct: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Score = 42.0 bits (97), Expect = 0.001
Identities = 49/191 (25%), Positives = 74/191 (38%), Gaps = 26/191 (13%)
Query: 36 PEVAPPAHRRPDHSGGSPSP----PTS-EPARSGHRGNRARGVSRSPPKKKNK---ASGR 87
PE P + GGSP P P S EP + R RSPPK K +S
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTR--DRSPPKSPEKLPQSSSS 418
Query: 88 RSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSE---QEHRRARNSDRDRHR 144
S P + + H++ + P+ HRE S ++R + RD+
Sbjct: 419 ESSPPSPQPTKVSRHAS-----SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSH 473
Query: 145 GHSHQRRTSNERPGSGQGQGRDRD---TQNLQAQEEEREFYNAR--RREHRQRNDVGGGG 199
H+ RR R + +GR R T+ ++ ++ +R +R R R+ G
Sbjct: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR 533
Query: 200 SESQELVPRPG 210
S S + RPG
Sbjct: 534 SRSPQ---RPG 541
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 23/155 (14%)
Query: 60 PARSGHRGNRA----RGVSRSPPKKKNKA------SGR-RSKSPRSKRNRSPHHSTVKVK 108
PAR G +R R +RSP ++++++ SGR RS++P ++R RS + +
Sbjct: 609 PARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP-ARRGRSRSRTPARRG 667
Query: 109 QEREDHPRRGREDRQHREPSEQEHRRARNSDRDR-------HRGHSHQRRTSNERPGSG- 160
+ R P R + R P+ + R+R R R RG SH RT R SG
Sbjct: 668 RSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHS-RTPQRRGRSGS 726
Query: 161 --QGQGRDRDTQNLQAQEEEREFYNARRREHRQRN 193
+ + + R +Q E +R R R+
Sbjct: 727 SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 14/159 (8%)
Query: 5 KSERER---GSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHR-RPDHSGGSPSPPTSEP 60
K+ER R G + DG P + ++ +PE P R S SP+P +
Sbjct: 131 KNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKK 190
Query: 61 ARSGHRGNRARGVSRSPPKKKNKASGRRSK--SPRSKRNRSPHHSTVKVKQEREDHPRRG 118
+ RG R+ S P+++ K S ++ K S + R T K K++ +D R+
Sbjct: 191 KKKKDRGRRSES---SSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKR 247
Query: 119 REDRQHREPSEQEHR-----RARNSDRDRHRGHSHQRRT 152
S + HR A +SD R R S +T
Sbjct: 248 SRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT 286
Score = 40.0 bits (92), Expect = 0.004
Identities = 53/223 (23%), Positives = 82/223 (36%), Gaps = 38/223 (17%)
Query: 49 SGGSPSPP-------------TSEP-ARSGHRGNRARGVSRSPPKKKNKASGRRSKS--- 91
SG SP P +S+P A+S R+R S PPK+K+K R+S S
Sbjct: 780 SGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSS 839
Query: 92 --PRSKRNRSPHHSTVKVKQEREDH--PRRGREDRQHREPSEQEHRRARNSDRDRHRGHS 147
P+ K P ++ Q E P+R R E S ++R R G S
Sbjct: 840 PHPKVKSGTPPRQGSITSPQANEQSVTPQR----RSCFESSPDPELKSRTPSRHSCSGSS 895
Query: 148 HQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVP 207
R S+ P R +++ Q + + + R+R H + S+
Sbjct: 896 PPRVKSSTPP-------RQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948
Query: 208 RPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPP 250
R + V ++ P + SG+ DT +K PP
Sbjct: 949 RSRSVSPCSNVESRLLPRYSHSGSSSPDTK------VKPETPP 985
Score = 40.0 bits (92), Expect = 0.004
Identities = 54/216 (25%), Positives = 78/216 (36%), Gaps = 28/216 (12%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSG 64
K R R S HR P ++ + R +P + RR S S + RS
Sbjct: 1862 KRSRSRASPATHRRSRSRTP---LISRRRSRSRTSPVSRRR------SRSRTSVTRRRSR 1912
Query: 65 HRGN---RARGVSRSPPKKKNKASGRRSKSPRSKRNRSP-------HHSTVKVKQER--- 111
R + R R SR+PP + ++ R + R R+R+P T V + R
Sbjct: 1913 SRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS 1972
Query: 112 EDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSH-----QRRTSNERPGSGQGQGRD 166
P R R P + R+R S R R S +RR+ + P + + + R
Sbjct: 1973 RTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRS 2032
Query: 167 RDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSES 202
R T L + A RR R R G S
Sbjct: 2033 R-TPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRS 2067
Score = 38.9 bits (89), Expect = 0.008
Identities = 36/105 (34%), Positives = 47/105 (44%), Gaps = 12/105 (11%)
Query: 44 RRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSK---SPRSKR---- 96
R P G S S +SE R + SP KK++ S RRS+ SPRSK
Sbjct: 716 RTPQRRGRSGS--SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL 773
Query: 97 --NRSPHHSTVKVKQEREDHPRRGRE-DRQHREPSEQEHRRARNS 138
RS S+ KQ+ + PRR R Q + S RR+R+S
Sbjct: 774 SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSS 818
Score = 37.0 bits (84), Expect = 0.031
Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 9/119 (7%)
Query: 29 VKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRG-NRARGVSRSPPKKKNKASGR 87
+ + R +P RR S SP T +RS R R SR+PP + ++
Sbjct: 1977 ITRRRSRSRTSPVTRRR---SRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS--- 2030
Query: 88 RSKSPRSKRNRSPHHSTVKV-KQEREDHPRRGREDRQ-HREPSEQEHRRARNSDRDRHR 144
RS++P R RS S + + ++ R PR R R R P R A S DR R
Sbjct: 2031 RSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSR 2089
Score = 35.8 bits (81), Expect = 0.069
Identities = 31/146 (21%), Positives = 51/146 (34%), Gaps = 12/146 (8%)
Query: 24 PAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSP------ 77
P K++R S + + S S S +S + S + + S SP
Sbjct: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
Query: 78 PKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQERE------DHPRRGREDRQHREPSEQE 131
P+ K + + P +R+RSP ++ R + R + + S
Sbjct: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Query: 132 HRRARNSDRDRHRGHSHQRRTSNERP 157
R +R R R SH+RR P
Sbjct: 2716 ERGSRRGQRGDSRSPSHKRRRETPSP 2741
Score = 35.8 bits (81), Expect = 0.069
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 15/114 (13%)
Query: 49 SGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRS-----KRNRSPHHS 103
S S S + PA+ G + + + KK RRS+SPR + +RS +S
Sbjct: 2640 SSSSSSSSSPSPAKPG-----PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694
Query: 104 TVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERP 157
V + R P+ D+Q SE+ RR + D R H +R T + RP
Sbjct: 2695 PV---ERRRPSPQPSPRDQQ-SSSSERGSRRGQRGD-SRSPSHKRRRETPSPRP 2743
Score = 34.7 bits (78), Expect = 0.15
Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 12/64 (18%)
Query: 39 APPAHRRPDHSGGSPSP-PTSEPARSGHRGNR--ARGVSRSPPKKKNKASGRRSKSPRSK 95
+P RRP SP P P + + S RG+R RG SRSP K+ R + SPR
Sbjct: 2694 SPVERRRP-----SPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRR----RETPSPRPM 2744
Query: 96 RNRS 99
R+RS
Sbjct: 2745 RHRS 2748
Score = 30.0 bits (66), Expect = 3.8
Identities = 32/130 (24%), Positives = 49/130 (37%), Gaps = 10/130 (7%)
Query: 52 SPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKS-----PRSKRNRSPHHSTVK 106
S S P + +R R R+R +S K K++ S RRS S P+ K P S
Sbjct: 743 SNSSPEMKKSRISSR--RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG 800
Query: 107 VKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHS-HQRRTSNERPGSGQGQGR 165
Q + R R P ++ +++ R H S H + S P G
Sbjct: 801 SSQPKAKSRTPPRRSRSSSSPPPKQ--KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSP 858
Query: 166 DRDTQNLQAQ 175
+ Q++ Q
Sbjct: 859 QANEQSVTPQ 868
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 53.1 bits (126), Expect = 4e-07
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 20/189 (10%)
Query: 52 SPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHST------- 104
S S S + S G+ S PK+K + S RS + +++R+RS +S
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESN 585
Query: 105 ---VKVKQEREDHPRR-GREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSG 160
VK++ R + RE R++R PS +E RR+R+ RDR + + R+ + R
Sbjct: 586 RARVKIRDRRRSNRNSIERERRRNRSPS-RERRRSRSRSRDRRTNRASRSRSRDRRKIDD 644
Query: 161 QGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPA 220
Q ++ + + +E+E R++ R R+ + +E R +K KE
Sbjct: 645 QRGNLSGNSHKHKGEAKEQE-----RKKERSRSIDKDRKKKDKE---REREQDKRKEKQK 696
Query: 221 KEKPSFELS 229
+E+ F+ S
Sbjct: 697 REEKDFKFS 705
Score = 38.1 bits (87), Expect = 0.014
Identities = 40/201 (19%), Positives = 80/201 (39%), Gaps = 24/201 (11%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSG---GSPSPPTSEPAR 62
S R SR R RD + R S + + D G G+ E
Sbjct: 613 SRERRRSRSRSRDR----------RTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKE 662
Query: 63 SGHRGNRARGVSRSPPKK----KNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRG 118
+ R+R + + KK + + R+ K R +++ ++K++RE
Sbjct: 663 QERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFS 722
Query: 119 RED----RQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQ--GRDRDTQNL 172
R + R S Q+ +++ D +H G R+S+E PGS + + + + +++
Sbjct: 723 RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSR 782
Query: 173 QAQEEEREFYNARRREHRQRN 193
++ +R A R+ H+ ++
Sbjct: 783 SVEKSQRSGKKASRK-HKSKS 802
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 53.1 bits (126), Expect = 4e-07
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 20/189 (10%)
Query: 52 SPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHST------- 104
S S S + S G+ S PK+K + S RS + +++R+RS +S
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESN 585
Query: 105 ---VKVKQEREDHPRR-GREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSG 160
VK++ R + RE R++R PS +E RR+R+ RDR + + R+ + R
Sbjct: 586 RARVKIRDRRRSNRNSIERERRRNRSPS-RERRRSRSRSRDRRTNRASRSRSRDRRKIDD 644
Query: 161 QGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPA 220
Q ++ + + +E+E R++ R R+ + +E R +K KE
Sbjct: 645 QRGNLSGNSHKHKGEAKEQE-----RKKERSRSIDKDRKKKDKE---REREQDKRKEKQK 696
Query: 221 KEKPSFELS 229
+E+ F+ S
Sbjct: 697 REEKDFKFS 705
Score = 38.1 bits (87), Expect = 0.014
Identities = 40/201 (19%), Positives = 80/201 (39%), Gaps = 24/201 (11%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSG---GSPSPPTSEPAR 62
S R SR R RD + R S + + D G G+ E
Sbjct: 613 SRERRRSRSRSRDR----------RTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKE 662
Query: 63 SGHRGNRARGVSRSPPKK----KNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRG 118
+ R+R + + KK + + R+ K R +++ ++K++RE
Sbjct: 663 QERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFS 722
Query: 119 RED----RQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQ--GRDRDTQNL 172
R + R S Q+ +++ D +H G R+S+E PGS + + + + +++
Sbjct: 723 RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSR 782
Query: 173 QAQEEEREFYNARRREHRQRN 193
++ +R A R+ H+ ++
Sbjct: 783 SVEKSQRSGKKASRK-HKSKS 802
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 52.8 bits (125), Expect = 5e-07
Identities = 40/191 (20%), Positives = 80/191 (41%), Gaps = 25/191 (13%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSG 64
K RER R+R R+ + G K++R E R+ E R
Sbjct: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER---------EKQRKE 88
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQH 124
R R + K++ K GRR + K K+ER++ R ++ R+
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRER---------------KKKKERKERERENKQRRER 133
Query: 125 REPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDR-DTQNLQAQEEEREFYN 183
+ ++ +R + R++ RG ++R ++ + + R+R + + + ++E RE
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193
Query: 184 ARRREHRQRND 194
R++E R++ +
Sbjct: 194 ERKKERRKKKE 204
Score = 46.2 bits (108), Expect = 5e-05
Identities = 32/165 (19%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 59 EPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRG 118
E R R R + R K++ + G++ K R KR R + ++E++ RR
Sbjct: 33 ESERKKERREREKR-KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 119 REDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEE 178
+E R+ ++ ++ R+ R + + +R N++ + + R + + + + E+
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 179 REFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEK 223
R+R+ R++ E +E ++KE KE+
Sbjct: 152 ERGKRERKRKKRKK--------EEREKKRERNRKERKKERERKER 188
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/166 (18%), Positives = 71/166 (42%), Gaps = 12/166 (7%)
Query: 58 SEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRR 117
S+P + R K++ + +R + + K+ R K ++ +E +R
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRK------KRERGKERERKR 79
Query: 118 GREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEE 177
++Q +E E+E R+ + + R R +R ++ + ++R+ +N Q +E
Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK------ERKERERENKQRRER 133
Query: 178 EREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEK 223
+R+ ++R ++ + G E + + K++E KE+
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKER 179
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 52.8 bits (125), Expect = 5e-07
Identities = 50/190 (26%), Positives = 73/190 (38%), Gaps = 21/190 (11%)
Query: 44 RRPDHSGGSPSPPTSEP-ARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNR-SPH 101
R HS SP+P S +S + R SRSP + SG+RS RS R+R SP
Sbjct: 399 RSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSP--SYSSKSGKRSPPSRSSRSRRSPS 456
Query: 102 HSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHR----GHSHQRRTSNER- 156
+S +ER+ P+ +D Q RE RR S + R H RR ++ R
Sbjct: 457 YSRYSPSRERD--PKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARK 514
Query: 157 ----------PGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELV 206
SG + ++ R + +R R +R S S
Sbjct: 515 RPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRS 574
Query: 207 PRPGGNNKEK 216
P PG ++ +
Sbjct: 575 PSPGSRSRSR 584
Score = 48.1 bits (113), Expect = 1e-05
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 25/147 (17%)
Query: 30 KQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRAR-----GVSRSPPKKKNKA 84
++++ E+ H PP+S + + R + S SP KKK K
Sbjct: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
Query: 85 SGRR--------------SKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQ 130
S ++ S SP+SKR H K++ PR+ R HR PS
Sbjct: 138 SSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRH-----KKQSRSRPRKSHRHRHHRCPSRS 192
Query: 131 EHRRAR-NSDRDRHRGHSHQRRTSNER 156
+ +R +S RHRG S + + R
Sbjct: 193 QSSESRPSSCESRHRGRSPEEGQKSRR 219
Score = 46.6 bits (109), Expect = 4e-05
Identities = 61/250 (24%), Positives = 84/250 (33%), Gaps = 44/250 (17%)
Query: 5 KSERERGSRRRH---RDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPA 61
K+ RE G+ R H D D+ P K+++ +R S SPSP +
Sbjct: 81 KTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKST----RKKRRRSSSYSPSPVKKKKK 136
Query: 62 RSGHRGNRARGVSR------SPPKKKNKASGRRSKSPRS---KRNRSPHHSTVKVKQERE 112
+S + R R S+ S PK K + R K RS K +R HH Q E
Sbjct: 137 KSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSE 196
Query: 113 DHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGS------------- 159
P + R P E + R R+S R + RP S
Sbjct: 197 SRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARG 256
Query: 160 ---GQGQGRDRDTQNLQAQEEEREFYNARRREHRQRND--------VGGGGSESQELVPR 208
G G D T+ R R +E+ ND S QE
Sbjct: 257 VITGSGSAADLFTKTASPLTTSR----GRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSP 312
Query: 209 PGGNNKEKEV 218
GG +K +E+
Sbjct: 313 SGGLSKSREL 322
Score = 33.1 bits (74), Expect = 0.45
Identities = 33/142 (23%), Positives = 48/142 (33%), Gaps = 20/142 (14%)
Query: 47 DHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVK 106
D + SPP+++ + + RG S K + SG S S S SP +
Sbjct: 286 DSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAM 345
Query: 107 VKQEREDHPRRGREDRQHREP------------------SEQEHRRARNSDRDRHRGHSH 148
+ E RGRE R + P S +R+S R SH
Sbjct: 346 L--ENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSH 403
Query: 149 QRRTSNERPGSGQGQGRDRDTQ 170
R+ N R Q R ++
Sbjct: 404 SSRSPNPRASPRYTQSRSTSSE 425
Score = 30.8 bits (68), Expect = 2.2
Identities = 40/157 (25%), Positives = 55/157 (35%), Gaps = 42/157 (26%)
Query: 7 ERERGSRRRH---------RDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPT 57
ERER RRR RD L A + + P + RP S T
Sbjct: 479 ERERARRRRRSYSPMRKRRRDSPSHLEARRITSARK-----RPIPYYRPSPSSSGSLSST 533
Query: 58 SEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRR 117
S S + + +R SRS + ++ RS+S R R R+ S+
Sbjct: 534 S----SWYSSSSSRSASRSYSRSRS-----RSRSRRRSRTRTSSSSS------------- 571
Query: 118 GREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSN 154
R PS R+R+ R R R S R S+
Sbjct: 572 ------SRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
Score = 30.4 bits (67), Expect = 2.9
Identities = 35/142 (24%), Positives = 57/142 (40%), Gaps = 10/142 (7%)
Query: 56 PTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQE--RED 113
PTS S RG ++ + + KK + SP +RS +++ + R
Sbjct: 351 PTSRGRES--RGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSP 408
Query: 114 HPRRGREDRQHREPSEQEHRRARNSDRDRHRG-HSHQRRTSNERPG---SGQGQGRDRDT 169
+PR Q R S ++ +R+ G S R+S R S R+RD
Sbjct: 409 NPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDP 468
Query: 170 QNLQ--AQEEEREFYNARRREH 189
+ + +Q+ ERE RRR +
Sbjct: 469 KYSEKDSQQRERERARRRRRSY 490
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 52.0 bits (123), Expect = 9e-07
Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 3/120 (2%)
Query: 75 RSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRR 134
R +K+ + R + R +R R + +++ ++ R DR E++ R
Sbjct: 302 RQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDR 361
Query: 135 ARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRND 194
R DRDR R S R R + + RDR+ + + +E ERE R RE + +
Sbjct: 362 DRERDRDRDRERSSDRNKDRSR---SREKSRDRERERERERERERERERERERERERERE 418
Score = 50.1 bits (118), Expect = 4e-06
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 68 NRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREP 127
++ R + ++K K R + + +R R + ++ERE R RE + RE
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERE----RERERERERE- 336
Query: 128 SEQEHRRARNSDRDRHRGHSHQRRTSNERP-------GSGQGQGRDRDTQNLQAQEEERE 180
E+E R R DRDR R R ER S + + R R + + +E ERE
Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Query: 181 FYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFE 227
R RE R+R E + R +K+++ E+ ++E
Sbjct: 397 RERERERE-REREREREREREREREREREREKDKKRDREEDEEDAYE 442
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/168 (21%), Positives = 67/168 (39%), Gaps = 5/168 (2%)
Query: 30 KQERLSPEVAP--PAHRRPDHSGGSPSPPTSE--PARSGHRGNRARGVSRSPPKKKNKAS 85
K++ +S E++ H++ + G E R R R R +++ +
Sbjct: 273 KRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERE 332
Query: 86 GRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRG 145
R K +R R + K+ D R DR S++ R+R+ ++ R R
Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRE 392
Query: 146 HSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRN 193
+R ER + + R+R+ + + +E ERE R RE + +
Sbjct: 393 RERERERERERERERERE-REREREREREREREREKDKKRDREEDEED 439
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/178 (22%), Positives = 69/178 (38%), Gaps = 9/178 (5%)
Query: 59 EPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRG 118
E R R R R R ++K K R + R R+R+ + ++ D R
Sbjct: 315 ERERERERREREREREREREREKEKERERERERDRD-RDRTKERDRDRDRERDRDRDRER 373
Query: 119 REDR-----QHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQ 173
DR + RE S ++ R R +R+R R +R ER + + +
Sbjct: 374 SSDRNKDRSRSREKS-RDREREREREREREREREREREREREREREREREREREKDKKRD 432
Query: 174 AQEEEREFYNARRREHRQRNDVGGGGS--ESQELVPRPGGNNKEKEVPAKEKPSFELS 229
+E+E + Y R+ E + R ++ E+ R EKE +E+ E++
Sbjct: 433 REEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMA 490
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/93 (21%), Positives = 45/93 (48%), Gaps = 14/93 (15%)
Query: 106 KVKQEREDHPR----RGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQ 161
++ + R+ H + +G+++++ +E ++ R R +R+R R +R ER
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER---RERERERERE---- 332
Query: 162 GQGRDRDTQNLQAQEEEREFYNARRREHRQRND 194
R+R+ + + +E ER+ R +E + D
Sbjct: 333 ---REREKEKERERERERDRDRDRTKERDRDRD 362
Score = 29.3 bits (64), Expect = 6.5
Identities = 15/82 (18%), Positives = 36/82 (43%)
Query: 107 VKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRD 166
++ E + RE + R+ ++ +++R +R ER + + R+
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERE 326
Query: 167 RDTQNLQAQEEEREFYNARRRE 188
R+ + + +E+E+E R R+
Sbjct: 327 REREREREREKEKERERERERD 348
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 23/203 (11%)
Query: 43 HRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGR-RSKSPRSKRNRSPH 101
H + + + G P T R G R +AR SR ++ + + R S R R S H
Sbjct: 3717 HEQSESAHGRAGPSTG--GRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYH 3774
Query: 102 HSTVKVKQEREDH----PRRGREDRQH-----REPSEQEHRRARNSDRDRHRGHSHQRRT 152
+V H +GR D H R S + ++ D RH G H +
Sbjct: 3775 EQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEAS 3834
Query: 153 ----SNERPGSGQGQG----RDRDTQNLQAQEEEREFY---NARRREHRQRNDVGGGGSE 201
S+ SGQG+ R R + +Q+ + E Y + RR E RN G +
Sbjct: 3835 TQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQ 3894
Query: 202 SQELVPRPGGNNKEKEVPAKEKP 224
S++ PG ++++ + P
Sbjct: 3895 SRDGSRHPGSSHRDTASHVQSSP 3917
Score = 43.1 bits (100), Expect = 4e-04
Identities = 43/145 (29%), Positives = 57/145 (39%), Gaps = 32/145 (22%)
Query: 63 SGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQERED--HPRRGRE 120
SG R +R RG S S + + + G S R + S +H +Q R+ HPR E
Sbjct: 2231 SGPRTSRPRGSSVS---QDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHE 2287
Query: 121 DR---------------QHREPSE-----QEHRRARNSDRDRHRGHSHQRRTSNERPGSG 160
DR H E S H +AR+S +RH H Q S+ G G
Sbjct: 2288 DRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG 2347
Query: 161 QGQG----RD---RDTQNLQAQEEE 178
GQ RD R + QA + E
Sbjct: 2348 HGQASSAVRDSGHRGSSGSQASDSE 2372
Score = 42.4 bits (98), Expect = 7e-04
Identities = 47/186 (25%), Positives = 67/186 (36%), Gaps = 31/186 (16%)
Query: 43 HRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGR-RSKSPRSKRNRSPH 101
H +PD + G TS R G +AR SR ++ + + R S R R S H
Sbjct: 475 HEQPDSAHGRTG--TSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHH 532
Query: 102 HSTVKVKQEREDH----PRRGREDRQH-----REPSEQEHRRARNSDRDRHRGHSH---- 148
+V H +GR D H R S Q ++ D RH G H
Sbjct: 533 EQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEAS 592
Query: 149 ------------QRRTSNERPGSGQGQ--GRDRDTQNLQAQEEEREFYNARRREHRQRND 194
Q ++S R QG +D D+Q +++ ER +A R H +
Sbjct: 593 SQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQG-HSEDSERWSGSASRNHHGSAQE 651
Query: 195 VGGGGS 200
GS
Sbjct: 652 QSRDGS 657
Score = 42.0 bits (97), Expect = 0.001
Identities = 49/210 (23%), Positives = 70/210 (33%), Gaps = 56/210 (26%)
Query: 48 HSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKAS---------GRRSKSPR--SKR 96
HSG +S SGH +G S P +N S G S R
Sbjct: 2529 HSGSRHHEASSRADSSGH-SQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSA 2587
Query: 97 NRSPHHSTVKVKQEREDHPRRGREDR---------------QHREPSE-----QEHRRAR 136
+R+ H S + ++ HPR +EDR +H + S H +AR
Sbjct: 2588 SRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2647
Query: 137 NSDRDRHRGHSHQRRTSNERPGSGQGQ------------------------GRDRDTQNL 172
+S +RH H Q S+ G G GQ D DTQ++
Sbjct: 2648 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV 2707
Query: 173 QAQEEEREFYNARRREHRQRNDVGGGGSES 202
A + + + R R+ G S S
Sbjct: 2708 SAHGQAGSHQQSHQESARGRSGETSGHSGS 2737
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/198 (22%), Positives = 72/198 (36%), Gaps = 41/198 (20%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGH 65
SER GS R+ G QE+L P + D +G S +S + + H
Sbjct: 2904 SERWSGSASRNHHGSA---------QEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRH 2954
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHR 125
+ G + S ++ ++G R S + S HS +
Sbjct: 2955 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI-------------------- 2994
Query: 126 EPSEQEHRRARNSDRDR-HRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNA 184
H +A ++ RD HRG+S + + NE G D DTQ++ A + +
Sbjct: 2995 -----GHGQASSAVRDSGHRGYSGSQASDNE------GHSEDSDTQSVSAHGQAGSHQQS 3043
Query: 185 RRREHRQRNDVGGGGSES 202
+ R R+ G S S
Sbjct: 3044 HQESARGRSGETSGHSGS 3061
Score = 40.0 bits (92), Expect = 0.004
Identities = 45/209 (21%), Positives = 69/209 (33%), Gaps = 18/209 (8%)
Query: 37 EVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARG----VSRSPPKKKNKASGRRSKSP 92
E + AH R S G E AR R + ++ + P + G +
Sbjct: 1773 EQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQS 1832
Query: 93 RSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSH---- 148
S H + QER D R R S Q ++ D RH G H
Sbjct: 1833 VDSSGHSGSHHSHTTSQERSD---VSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEAS 1889
Query: 149 QRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQ-------RNDVGGGGSE 201
R S+ GQGQ T Q ++ + E + RN +G +
Sbjct: 1890 SRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQ 1949
Query: 202 SQELVPRPGGNNKEKEVPAKEKPSFELSG 230
S++ PG +++++ S SG
Sbjct: 1950 SRDGSRHPGSHHEDRAGHGHSADSSRQSG 1978
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/174 (23%), Positives = 58/174 (33%), Gaps = 33/174 (18%)
Query: 62 RSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVK------VKQERED-- 113
RSG R R+ K S P + + HH + Q+ +D
Sbjct: 782 RSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTI 841
Query: 114 --HP---RRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQ----G 164
HP RRGR+ H + + DR H G H TS R + +GQ
Sbjct: 842 RGHPGSSRRGRQGSHHEQ----------SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRS 891
Query: 165 RDRDTQNLQAQEEEREFYNARRREHRQRNDV------GGGGSESQELVPRPGGN 212
R T+N + + +R E D+ G G SE R G +
Sbjct: 892 ASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSS 945
Score = 39.7 bits (91), Expect = 0.005
Identities = 52/240 (21%), Positives = 87/240 (36%), Gaps = 44/240 (18%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGH 65
SER GS R+ G QE+ P D +G S +S + + H
Sbjct: 2256 SERRSGSASRNHHGSA---------QEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHH 2306
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTV---KVKQEREDHPRRGREDR 122
N + G + S ++ ++G R S + S HS + + D RG
Sbjct: 2307 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGS 2366
Query: 123 Q------HREPSE-----------------QEHRRARNSDRDRHRGHSHQRRTSNERPGS 159
Q H E S+ QE R R++ R G + +++E+ S
Sbjct: 2367 QASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSES 2426
Query: 160 GQGQ-----GRDRDTQNLQAQEEEREFYNARRRE----HRQRNDVGGGGSESQELVPRPG 210
G+ G + + + QA++ R + ++ H + G GS ++LV R G
Sbjct: 2427 AHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSG 2486
Score = 38.5 bits (88), Expect = 0.011
Identities = 43/200 (21%), Positives = 69/200 (34%), Gaps = 31/200 (15%)
Query: 57 TSEPARSGHRGNRARGVSRSPPKKKNKASGRRSK-SPRSKRNRSPHHSTVKVKQEREDH- 114
TS R G +AR SR ++ + + R S R R S H +V H
Sbjct: 1136 TSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHH 1195
Query: 115 ---PRRGREDRQH-----REPSEQEHRRARNSDRDRHRGHSH----------------QR 150
+GR D H R S Q + ++ D RH G H Q
Sbjct: 1196 SHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQE 1255
Query: 151 RTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPG 210
++S R QG +D+ + + ++ + R H G +S++ PG
Sbjct: 1256 QSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHH-----GSSREQSRDGSRHPG 1310
Query: 211 GNNKEKEVPAKEKPSFELSG 230
+ +++ S SG
Sbjct: 1311 FHQEDRASHGHSADSSRQSG 1330
Score = 38.1 bits (87), Expect = 0.014
Identities = 39/140 (27%), Positives = 50/140 (35%), Gaps = 27/140 (19%)
Query: 47 DHSGGSPSPPTSEPARSGHRGNRARGVS-----RSPPKKKNKASGRRSKSPRSKRNRSPH 101
D SGG RSG G+ VS S + ++GRR S + S
Sbjct: 3374 DRSGG----------RSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 3423
Query: 102 HSTVKVKQER-EDHPRRGREDRQ--HREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPG 158
HS + Q+ HP R RQ H E S DR H G H TS R
Sbjct: 3424 HSASQEGQDTIRGHPGSSRRGRQGSHYEQSV---------DRSGHSGSHHSHTTSQGRSD 3474
Query: 159 SGQGQGRDRDTQNLQAQEEE 178
+ +GQ R +E+
Sbjct: 3475 ASRGQSGSRSASRQTRNDEQ 3494
Score = 38.1 bits (87), Expect = 0.014
Identities = 42/159 (26%), Positives = 55/159 (34%), Gaps = 38/159 (23%)
Query: 58 SEPARSGHRGNRARGVSRSPPKKKNKAS---------GRRSKSPRSKRNRSPHHSTVKVK 108
S A S +G S P +N+ S G S R + S +H +
Sbjct: 3510 STQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQE 3569
Query: 109 QERED--HPRRGREDR---------------QHREPSE-----QEHRRARNSDRDRHRGH 146
Q R+ HP EDR H E S H +AR+S +RH H
Sbjct: 3570 QSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSH 3629
Query: 147 SHQRRTSNERPGSGQGQG----RD---RDTQNLQAQEEE 178
Q S+ G G GQ RD R + QA + E
Sbjct: 3630 HQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE 3668
Score = 37.7 bits (86), Expect = 0.018
Identities = 35/150 (23%), Positives = 58/150 (38%), Gaps = 15/150 (10%)
Query: 64 GHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQ 123
G ++R SR P +G + S+++ + H + Q H + R
Sbjct: 1944 GSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSH-EQARSSAG 2002
Query: 124 HREPSEQEHRRARNSDRDRHRGHSHQR-----RTSNERPGSG------QGQGRDRDTQNL 172
R S H + +++D RH G H + R S R SG +G D DTQ++
Sbjct: 2003 ERHGS---HHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSV 2059
Query: 173 QAQEEEREFYNARRREHRQRNDVGGGGSES 202
AQ + + + R ++ G S S
Sbjct: 2060 SAQGKAGPHQQSHKESARGQSGESSGRSGS 2089
Score = 37.4 bits (85), Expect = 0.024
Identities = 51/240 (21%), Positives = 82/240 (34%), Gaps = 44/240 (18%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGH 65
SER GS R+ G E+ P D + S +S + + H
Sbjct: 310 SERHSGSASRNHHGSA---------WEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRH 360
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTV---KVKQEREDHPRRGREDR 122
+RG + S ++ + G R S + S HS + D RG
Sbjct: 361 AETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS 420
Query: 123 QH-----------------------REPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGS 159
Q R+ S QE R R+ +R G S + +++E+P S
Sbjct: 421 QASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDS 480
Query: 160 GQGQ-----GRDRDTQNLQAQEEEREFYNARR----REHRQRNDVGGGGSESQELVPRPG 210
G+ G + + + QA++ R + R H + G GS ++ V R G
Sbjct: 481 AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG 540
Score = 37.0 bits (84), Expect = 0.031
Identities = 34/125 (27%), Positives = 46/125 (36%), Gaps = 17/125 (13%)
Query: 62 RSGHRGNRARGVS-----RSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQER-EDHP 115
RSG G+ VS S + ++GRR S + S HS + Q+ HP
Sbjct: 1110 RSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHP 1169
Query: 116 --RRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQ 173
RRG H E S DR H G H TS R + GQ R
Sbjct: 1170 GSRRGGRQGSHHEQSV---------DRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQT 1220
Query: 174 AQEEE 178
++++
Sbjct: 1221 RKDKQ 1225
Score = 37.0 bits (84), Expect = 0.031
Identities = 50/238 (21%), Positives = 81/238 (34%), Gaps = 20/238 (8%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRP--------DHSGGSPSPP 56
+S R+R R R G + + E RR D S S S
Sbjct: 3370 ESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE 3429
Query: 57 TSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPR 116
+ R GH G+ RG S ++ SG S S S + + R
Sbjct: 3430 GQDTIR-GHPGSSRRGRQGSHYEQSVDRSGH-SGSHHSHTTSQGRSDASRGQSGSRSASR 3487
Query: 117 RGREDRQHREPSEQE----HRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNL 172
+ R D Q + S H + +D RH S Q +++ R QG +D+ +
Sbjct: 3488 QTRNDEQSGDGSRHSWSHHHEASTQADSSRH-SQSGQGQSAGPRTSRNQGSSVSQDSDSQ 3546
Query: 173 QAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSG 230
E+ + + R HR G +S++ P +++++ S SG
Sbjct: 3547 GHSEDSERWSGSASRNHR-----GSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSG 3599
Score = 37.0 bits (84), Expect = 0.031
Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 18/157 (11%)
Query: 45 RPDHSGGSPSPPTSEP-ARSGHRGNRARGVSRSPPKKKNKASGRRSKSPR---------- 93
R HSG S TS+ + + H + +R SR ++ G R R
Sbjct: 3780 RSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADS 3839
Query: 94 SKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTS 153
S+ ++S + ++ R ++ P + E RR+ ++ R+ H Q R
Sbjct: 3840 SRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSE-RRSESASRNHHGSSREQSRDG 3898
Query: 154 NERPGSGQGQGRDRDT-QNLQAQEEEREFYNARRREH 189
+ PGS RDT ++Q+ + + A+ H
Sbjct: 3899 SRHPGSSH-----RDTASHVQSSPVQSDSSTAKEHGH 3930
Score = 36.6 bits (83), Expect = 0.041
Identities = 50/246 (20%), Positives = 86/246 (34%), Gaps = 20/246 (8%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRP--------DHSGGSPSPP 56
+S R+R R R G + + E P R D+S S S
Sbjct: 777 ESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQD 836
Query: 57 TSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPR 116
+ R GH G+ RG S ++ SG S S S + + R
Sbjct: 837 GQDTIR-GHPGSSRRGRQGSHHEQSVDRSGH-SGSHHSHTTSQGRSDASRGQSGSRSASR 894
Query: 117 RGREDRQHREPSE----QEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNL 172
R + Q R+ S + H + ++D RH + Q ++ R QG +D+ +
Sbjct: 895 TTRNEEQSRDGSRHSGSRHHEASSHADISRH-SQAGQGQSEGSRTSRRQGSSVSQDSDSE 953
Query: 173 QAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGAL 232
E+ + + R HR G +S+ P +++++ S SG
Sbjct: 954 GHSEDSERWSGSASRNHR-----GSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTP 1008
Query: 233 LEDTNT 238
+T++
Sbjct: 1009 HAETSS 1014
Score = 36.6 bits (83), Expect = 0.041
Identities = 43/178 (24%), Positives = 57/178 (32%), Gaps = 29/178 (16%)
Query: 45 RPDHSGGSPSPPTSEPARSGHRGNR-ARGVSRSPPKKKNKASGRRSKSPR----SKRNRS 99
R HSG S TS+ RG +R SR K+ G R S S
Sbjct: 2160 RSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADS 2219
Query: 100 PHHSTVKVKQEREDHPRRGR-----EDRQHREPSEQEHRRARNSDRDRHR--------GH 146
HS V Q R R +D SE RR+ ++ R+ H G
Sbjct: 2220 SRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGS 2279
Query: 147 SHQRRTSNERPGSGQGQGRDRDT-----------QNLQAQEEEREFYNARRREHRQRN 193
H R +R G G R + Q + E+ R R H Q++
Sbjct: 2280 RHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQS 2337
Score = 36.6 bits (83), Expect = 0.041
Identities = 44/198 (22%), Positives = 70/198 (35%), Gaps = 41/198 (20%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGH 65
SER GS R+ G QE+ P D +G S +S + + H
Sbjct: 3552 SERWSGSASRNHRGSA---------QEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHH 3602
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHR 125
N + G + S ++ ++G R S + S HS +
Sbjct: 3603 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI-------------------- 3642
Query: 126 EPSEQEHRRARNSDRDR-HRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNA 184
H +A ++ RD HRG S + + +E G D DTQ++ A + +
Sbjct: 3643 -----GHGQASSAVRDSGHRGSSGSQASDSE------GHSEDSDTQSVSAHGQAGPHQQS 3691
Query: 185 RRREHRQRNDVGGGGSES 202
+ R R+ G S S
Sbjct: 3692 HQESTRGRSAGRSGRSGS 3709
Score = 36.2 bits (82), Expect = 0.053
Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 28/155 (18%)
Query: 57 TSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPR 116
TS+ R + RG SR + ++ S+ +R+ H S + ++ HPR
Sbjct: 279 TSQVPLQESRTRKRRG-SRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPR 337
Query: 117 RGREDR---------------QHREPSEQ-----EHRRARNSDRDRHRGHSHQRRTSNER 156
EDR +H E S + H +AR+S +RH Q S+
Sbjct: 338 SHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRH 397
Query: 157 PGSGQGQGRD-------RDTQNLQAQEEEREFYNA 184
+G+GQ R + QA + E N+
Sbjct: 398 SATGRGQASSAVSDRGHRGSSGSQASDSEGHSENS 432
Score = 36.2 bits (82), Expect = 0.053
Identities = 51/253 (20%), Positives = 79/253 (31%), Gaps = 49/253 (19%)
Query: 2 KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPA 61
+A S ER R + D +G+ +Q A A R H G S S T+
Sbjct: 1348 QARSSPGERHGSRHQQSADSSRHSGIGHRQ-------ASSAVRDSGHRGSSGSQVTNSEG 1400
Query: 62 RSGHRGNRARGV--SRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRR-- 117
S ++ P ++ +K S R S R+RS + +Q H +
Sbjct: 1401 HSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAP 1460
Query: 118 ---GREDRQHREPSEQEHRRA-------------------------RNSDRDRHRGHSHQ 149
GR+ +H + A ++ DR H G+ H
Sbjct: 1461 STGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHS 1520
Query: 150 RRTSNERPGSGQGQGRDRDTQNLQAQEEE----------REFYNARRREHRQRNDVGGGG 199
T R + GQ R EE+ R + R + + VG G
Sbjct: 1521 HTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGE 1580
Query: 200 SESQELVPRPGGN 212
S + R G +
Sbjct: 1581 SAGSKTSRRQGSS 1593
Score = 35.8 bits (81), Expect = 0.069
Identities = 42/198 (21%), Positives = 71/198 (35%), Gaps = 41/198 (20%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGH 65
SER GS R+ G +E+ P + D + S +S + + H
Sbjct: 1283 SERLSGSASRNHHGS---------SREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHR 125
+ + G + S ++ + G R S + S HS +
Sbjct: 1334 TESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI-------------------- 1373
Query: 126 EPSEQEHRRARNSDRDR-HRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNA 184
HR+A ++ RD HRG S + T++E G D DTQ++ A + +
Sbjct: 1374 -----GHRQASSAVRDSGHRGSSGSQVTNSE------GHSEDSDTQSVSAHGQAGPHQQS 1422
Query: 185 RRREHRQRNDVGGGGSES 202
+ R ++ G S S
Sbjct: 1423 HKESARGQSGESSGRSRS 1440
Score = 35.4 bits (80), Expect = 0.091
Identities = 40/176 (22%), Positives = 59/176 (33%), Gaps = 18/176 (10%)
Query: 45 RPDHSGGSPSPPTSEPARSGHRGNRA-RGVSRSPPKKKNKASGRRSKSPR----SKRNRS 99
R HSG S T + G R SR ++ G R R S R S
Sbjct: 1511 RSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGS 1570
Query: 100 PHHSTVKVKQEREDHPRRGR-----EDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSN 154
HS V + R + +DR SE RR+ ++ R+ + Q R +
Sbjct: 1571 SRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGS 1630
Query: 155 ERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPG 210
P S Q DR + A+ + H + + G S ++ PG
Sbjct: 1631 RNPRSHQ---EDRASHGHSAESSRQS-----GTRHAETSSGGQAASSQEQARSSPG 1678
Score = 35.4 bits (80), Expect = 0.091
Identities = 37/154 (24%), Positives = 56/154 (36%), Gaps = 17/154 (11%)
Query: 74 SRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQER-EDHPRRGREDRQHREPSEQEH 132
S S + ++G R S + S HS + Q+ HP R RQ S QE
Sbjct: 2100 SESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQG---SHQE- 2155
Query: 133 RRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEE---------REFYN 183
++ DR H G H TS R + +GQ R +E+ +
Sbjct: 2156 ---QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHE 2212
Query: 184 ARRREHRQRNDVGGGGSESQELVPRPGGNNKEKE 217
A R+ + G G S RP G++ ++
Sbjct: 2213 ASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQD 2246
Score = 35.0 bits (79), Expect = 0.12
Identities = 57/230 (24%), Positives = 84/230 (36%), Gaps = 23/230 (10%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSP-EVAPPAHRRP-DHSGGSPSPPTSEPARS 63
+E R S RH + A +Q R SP E H++ D S S + + +
Sbjct: 1647 AESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVV 1706
Query: 64 GHRGNR-ARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDR 122
G GNR + G S + ++ S +S S + PH + + + R GR
Sbjct: 1707 GDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAG--PHQQSHQESTRGQSGERSGRSGS 1764
Query: 123 -----QHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQ-------GRDRDTQ 170
E SE H R S R R Q R S+ S +GQ G R +
Sbjct: 1765 FLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGR 1824
Query: 171 NLQAQEEEREFYNARRREH-----RQRNDVGGGGSESQELVPRPGGNNKE 215
E+ + H ++R+DV G S S+ V R N K+
Sbjct: 1825 QGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRS-VSRQTRNEKQ 1873
Score = 35.0 bits (79), Expect = 0.12
Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 24/149 (16%)
Query: 48 HSGGSPSPPTSEPARSGHRGNR-ARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTV- 105
HSG S TS+ RG +R SR+ + + SG S+ S+ + + H+ +
Sbjct: 3135 HSGSHHSHTTSQGRSDASRGQSGSRSASRTT--RNEEQSGDSSRHSVSRHHEASTHADIS 3192
Query: 106 ---KVKQEREDHPRRGR----------------EDRQHREPSEQEHRRARNSDRDRHRGH 146
+ Q + + RR R ED + S + R ++ RH G
Sbjct: 3193 RHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRH-GS 3251
Query: 147 SHQRRTSNERPGSGQGQGRDRDTQNLQAQ 175
H R +R G G R R + A+
Sbjct: 3252 RHPRSHHEDRAGHGHSADRSRQSGTRHAE 3280
Score = 34.7 bits (78), Expect = 0.15
Identities = 46/199 (23%), Positives = 65/199 (32%), Gaps = 56/199 (28%)
Query: 51 GSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKAS---------GRRSKSPRSKRNRSPH 101
GS S A S +G S P +N+ S G S R + S +
Sbjct: 585 GSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 644
Query: 102 HSTVKVKQERED--HPRRGREDR---------------QHREPSEQ-----EHRRARNS- 138
H +Q R+ HPR EDR +H + S H +AR+S
Sbjct: 645 HHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSA 704
Query: 139 -------------DRDRHRGHSHQR-----RTSNERPGSG------QGQGRDRDTQNLQA 174
D RH G H + R S R SG +G D DTQ++
Sbjct: 705 GERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSG 764
Query: 175 QEEEREFYNARRREHRQRN 193
+ + + R R+
Sbjct: 765 HGQAGHHQQSHQESARDRS 783
Score = 34.3 bits (77), Expect = 0.20
Identities = 30/123 (24%), Positives = 42/123 (34%), Gaps = 13/123 (10%)
Query: 62 RSGHRGNRARGVSRSPP------KKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHP 115
RSG G+ VS + GR+ R+ S H ++ + + HP
Sbjct: 461 RSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHP 520
Query: 116 RRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQ 175
R RQ H ++ N R H G H TS R + GQ R
Sbjct: 521 GSSRGGRQG-----SHHEQSVN--RSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRN 573
Query: 176 EEE 178
EE+
Sbjct: 574 EEQ 576
Score = 34.3 bits (77), Expect = 0.20
Identities = 43/165 (26%), Positives = 57/165 (34%), Gaps = 8/165 (4%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSP-EVAPPAHRRPDHSGGSPSPPTSEPARSG 64
++R R S RH + A +Q R SP E H++ S P + A S
Sbjct: 3268 ADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQ-ASSA 3326
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRS-PHHSTVKVKQEREDHPRRGREDR- 122
R +R G S S S S ++ PH + + R GR
Sbjct: 3327 VRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSF 3386
Query: 123 ----QHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQ 163
E SE H R R S R H Q R S+ S +GQ
Sbjct: 3387 LYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 3431
Score = 33.5 bits (75), Expect = 0.34
Identities = 50/241 (20%), Positives = 78/241 (32%), Gaps = 26/241 (10%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGH 65
SER GS R+ G QE+ P D +G S +S + + H
Sbjct: 959 SERWSGSASRNHRGSA---------QEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPH 1009
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHR 125
+ G + S ++ + G R S + S HS + +Q G
Sbjct: 1010 AETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGS 1069
Query: 126 EPSEQEHRRARNSDRDRHRGHS-----HQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE 180
+ S+ E + SD GH Q + R SG GR + E+ E
Sbjct: 1070 QASDSE-GHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSE 1128
Query: 181 FYNARRR---------EHRQRNDVG--GGGSESQELVPRPGGNNKEKEVPAKEKPSFELS 229
+ R R H Q D E Q+ + G+ + + + S + S
Sbjct: 1129 SAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRS 1188
Query: 230 G 230
G
Sbjct: 1189 G 1189
Score = 33.5 bits (75), Expect = 0.34
Identities = 31/121 (25%), Positives = 42/121 (34%), Gaps = 9/121 (7%)
Query: 48 HSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKV 107
HSG +S SGHRG+ S S + + ++S + PH + +
Sbjct: 3639 HSGIGHGQASSAVRDSGHRGSSGSQASDS----EGHSEDSDTQSVSAHGQAGPHQQSHQE 3694
Query: 108 KQEREDHPRRGREDR-----QHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQG 162
R GR E SE H RA S R Q R S+ S +G
Sbjct: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEG 3754
Query: 163 Q 163
Q
Sbjct: 3755 Q 3755
Score = 33.1 bits (74), Expect = 0.45
Identities = 27/122 (22%), Positives = 41/122 (33%), Gaps = 13/122 (10%)
Query: 63 SGHRGNRARGVSRSPPKKKN------KASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPR 116
SGH G+ VS + + GR+ ++ S H ++ + HP
Sbjct: 2732 SGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPG 2791
Query: 117 RGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQE 176
R RQ + + D H G H TS R + +GQ R E
Sbjct: 2792 SSRGGRQG-------YHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE 2844
Query: 177 EE 178
E+
Sbjct: 2845 EQ 2846
Score = 32.7 bits (73), Expect = 0.59
Identities = 22/116 (18%), Positives = 43/116 (37%), Gaps = 4/116 (3%)
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQH 124
HR + +++NK + +R S + NR + K +E +++
Sbjct: 101 HRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKE 160
Query: 125 REPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE 180
R+ HR + + +T N R G R R ++ L+ +E+ E
Sbjct: 161 RKGYSPTHREEEYGKNHHNSSKKEKNKTENTR----LGDNRKRLSERLEEKEDNEE 212
Score = 32.7 bits (73), Expect = 0.59
Identities = 27/122 (22%), Positives = 41/122 (33%), Gaps = 13/122 (10%)
Query: 63 SGHRGNRARGVSRSPPKKKN------KASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPR 116
SGH G+ VS + + GR+ ++ S H ++ + HP
Sbjct: 3056 SGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPG 3115
Query: 117 RGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQE 176
R RQ + + D H G H TS R + +GQ R E
Sbjct: 3116 SSRGGRQG-------YHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE 3168
Query: 177 EE 178
E+
Sbjct: 3169 EQ 3170
Score = 32.3 bits (72), Expect = 0.77
Identities = 37/152 (24%), Positives = 51/152 (33%), Gaps = 17/152 (11%)
Query: 62 RSGHRGNRARGVS-----RSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQER-EDHP 115
RSG G+ VS S + ++G R S + S HST + Q+ HP
Sbjct: 2407 RSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHP 2466
Query: 116 RRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQG----QGRDRDTQN 171
RQ + DR H G H TS R + G + R T+N
Sbjct: 2467 GSSSGGRQGSHYEQLV-------DRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRN 2519
Query: 172 LQAQEEEREFYNARRREHRQRNDVGGGGSESQ 203
+ + +R E R D G Q
Sbjct: 2520 DEQSGDGSRHSGSRHHEASSRADSSGHSQVGQ 2551
Score = 32.3 bits (72), Expect = 0.77
Identities = 49/241 (20%), Positives = 77/241 (31%), Gaps = 26/241 (10%)
Query: 6 SERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGH 65
SER GS R+ G V QE+ P D +G S S + + H
Sbjct: 3228 SERWSGSASRNHRGSV---------QEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRH 3278
Query: 66 RGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHR 125
+ G + S ++ + G R S + S HS + + + R R
Sbjct: 3279 AETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIP-RGQASSAVRDSRHWGSSG 3337
Query: 126 EPSEQEHRRARNSDRDRHRGHS-----HQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE 180
+ + SD GH Q + R SG GR + E+ E
Sbjct: 3338 SQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSE 3397
Query: 181 FYNARRR---------EHRQRNDVG--GGGSESQELVPRPGGNNKEKEVPAKEKPSFELS 229
+ R R H Q D E Q+ + G+++ + + S + S
Sbjct: 3398 SAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRS 3457
Query: 230 G 230
G
Sbjct: 3458 G 3458
Score = 32.0 bits (71), Expect = 1.0
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 8/123 (6%)
Query: 111 REDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDT- 169
+E+ P G + R+H + E + + +R R S +RR N R G+ R+T
Sbjct: 91 KENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERR--NNRKGNKGRSKSPRETG 148
Query: 170 ---QNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELV--PRPGGNNKEKEVPAKEKP 224
++++ER+ Y+ RE + + + R G N K +EK
Sbjct: 149 GKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKE 208
Query: 225 SFE 227
E
Sbjct: 209 DNE 211
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 51.6 bits (122), Expect = 1e-06
Identities = 38/177 (21%), Positives = 75/177 (42%), Gaps = 13/177 (7%)
Query: 54 SPPTSEPARSGHRGNRARGV-SRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQERE 112
S P ++P R R + +R KK+ ++ ++ + R KR R + + ++E
Sbjct: 26 SKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE 85
Query: 113 DHPRRGREDRQHR------EPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRD 166
R +E+R+ + E E E + R + RG + + ER + + R
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 167 RDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEK 223
+ + +E+ERE ++RE +Q G + +E + K++E KE+
Sbjct: 146 ERERKKEEREKERERKERKKRERKQ------VGEKEEERKEKERKERKKRERNRKER 196
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 7/138 (5%)
Query: 62 RSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRED 121
+ G R R + +K+NK + K R K+ + T K +ERE R RE+
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEK--RKKKEKKERGRTSKEGKERERKEERKREE 143
Query: 122 RQHRE--PSEQEHRRARNSDRDRHR---GHSHQRRTSNERPGSGQGQGRDRDTQNLQAQE 176
R+ RE E+E R R + R R G + R ER + + ++ + + ++
Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK 203
Query: 177 EEREFYNARRREHRQRND 194
E RE R+++ ++ +
Sbjct: 204 ERRERKKERKKKEERKKE 221
Score = 46.6 bits (109), Expect = 4e-05
Identities = 41/194 (21%), Positives = 78/194 (40%), Gaps = 27/194 (13%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSG 64
K RER R+R R+ + K+ER + + G R
Sbjct: 61 KERREREKRKREREKE--------RKRER----------GKKEKKGERKKEERERKKRRR 102
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSKSPRSK-----RNRSPHHSTVKVKQERE-DHPRRG 118
+ N+ KK+ K GR SK + + R R + K+ERE + R+
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162
Query: 119 REDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEE 178
R+ R+ ++ E+E R ++R + +++ ER + + R+R + + +E +
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE---RKERRERKKERKKKEERK 219
Query: 179 REFYNARRREHRQR 192
+E R+ R++
Sbjct: 220 KERQKDRQTNWREK 233
Score = 43.5 bits (101), Expect = 3e-04
Identities = 39/177 (22%), Positives = 67/177 (37%), Gaps = 25/177 (14%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSG 64
K ERER RRR + E E ++ G S E R
Sbjct: 92 KEERERKKRRREK--------------ENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQH 124
R R + +KK + R + R KR R +V ++ E+ + R++R+
Sbjct: 138 ERKREER---KERERKKEEREKERERKERKKRERK------QVGEKEEERKEKERKERKK 188
Query: 125 REPSEQEHR--RARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEER 179
RE + +E + R R R+R + + ER Q R+++ + +E ++
Sbjct: 189 RERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 51.6 bits (122), Expect = 1e-06
Identities = 68/255 (26%), Positives = 91/255 (35%), Gaps = 39/255 (15%)
Query: 24 PAG-VVVKQERLSPEVAPPAHRRP-DHSGGSPSPPTSEPARSGHRGNRARGVSRS----- 76
P G +V + RL+ P P D G GHRG R + S S
Sbjct: 108 PGGHIVAETPRLTEGAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPP 167
Query: 77 PPKKKNKASG-------RRSKSPRSKRNRSPHHSTVK-VKQEREDHPRRG-REDRQHREP 127
P KKK K G RR +S S + SP K VK+ R D G R R+HR
Sbjct: 168 PKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSR 227
Query: 128 SEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQ--------GQGRDRDTQNLQAQEEER 179
S + R+ +N ++ R S RR+ GS R + + ++E R
Sbjct: 228 SSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGR 287
Query: 180 EFYNARRREHR-------------QRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSF 226
+ + R R QRN GG G S RPG + + P+ P
Sbjct: 288 KTGSQRSSGSRSPSPSGGSGWGSPQRN--GGSGQRSGAHGGRPGSAHSPPDKPSSPSPRV 345
Query: 227 ELSGALLEDTNTFRG 241
A T RG
Sbjct: 346 RDKAAAAAPTPPARG 360
Score = 44.7 bits (104), Expect = 1e-04
Identities = 54/206 (26%), Positives = 73/206 (35%), Gaps = 46/206 (22%)
Query: 3 AVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAH--------RRPDHSG---G 51
A + R R RRR R A ++ R P APP R SG G
Sbjct: 383 AGRRRRRRRRRRRSRSS-----ASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRG 437
Query: 52 SPSPPTSEPARSGHRGNRARGVSRSPPKKKNKAS------GRRSKSPRSKRNRSPHHSTV 105
+P P + GH G+ R R P + S GRR +RSP
Sbjct: 438 APGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPG---- 493
Query: 106 KVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGS----GQ 161
HPR R PS+ R A R HS R S ++P S G+
Sbjct: 494 -------PHPRSWSSSRS---PSKSRSRSAEK------RPHSPSRSPSPKKPLSRDKDGE 537
Query: 162 GQGRDRDTQNLQAQEEEREFYNARRR 187
G+ R + + +A+ R + R+R
Sbjct: 538 GRARHSEAEATRARRRSRSYSPIRKR 563
Score = 33.9 bits (76), Expect = 0.26
Identities = 51/199 (25%), Positives = 69/199 (34%), Gaps = 49/199 (24%)
Query: 15 RHRDGDVVLPAGVVVKQERLSPEVAPPAHRRP------DHSGGSPSPPTS------EPAR 62
RH G P+ + SP P HR S GS SP S P R
Sbjct: 254 RHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQR 313
Query: 63 SGHRGNRAR------GVSRSPPKKKNKASGR-------RSKSPRSKRNRSPHHSTVKVKQ 109
+G G R+ G + SPP K + S R + +P ++ SP + Q
Sbjct: 314 NGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQ 373
Query: 110 EREDHP--------RRGREDRQHREPSEQEHRRARNSDRDRH-RGHSH---QRRTSNE-- 155
R RR R R+ R + RR R R RG S + R+S++
Sbjct: 374 GRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSG 433
Query: 156 ----------RPGSGQGQG 164
PGS +G G
Sbjct: 434 SGRGAPGPGPEPGSERGHG 452
Score = 33.1 bits (74), Expect = 0.45
Identities = 44/151 (29%), Positives = 59/151 (39%), Gaps = 28/151 (18%)
Query: 9 ERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHS--GGSPSPPTSEPARSGHR 66
E GS R H G K+ + P A PA P G P +RS
Sbjct: 444 EPGSERGH---------GGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGP 494
Query: 67 GNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHRE 126
R+ SRSP K +++++ +R SP +RSP S K +D R R
Sbjct: 495 HPRSWSSSRSPSKSRSRSAEKRPHSP----SRSP--SPKKPLSRDKDGEGRARH------ 542
Query: 127 PSEQEHRRARNSDRDRHRGHSHQRRTSNERP 157
SE E RAR R R +S R+ + P
Sbjct: 543 -SEAEATRARR----RSRSYSPIRKRRRDSP 568
Score = 29.6 bits (65), Expect = 5.0
Identities = 31/134 (23%), Positives = 43/134 (32%), Gaps = 15/134 (11%)
Query: 2 KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPA 61
K + +++ R RH + + + R S +P RR D SP EP
Sbjct: 528 KPLSRDKDGEGRARHSEAEAT-------RARRRSRSYSPIRKRRRD------SPSFMEPR 574
Query: 62 RSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRED 121
R R R P + + R+ SP HS H R R
Sbjct: 575 RITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSR--SHGTRSRTR 632
Query: 122 RQHREPSEQEHRRA 135
R PS H R+
Sbjct: 633 SPSRTPSPSYHSRS 646
Score = 29.3 bits (64), Expect = 6.5
Identities = 27/107 (25%), Positives = 36/107 (33%), Gaps = 7/107 (6%)
Query: 35 SPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRS 94
S +P AH R G S + P +R+ SRS +K S RS SP+
Sbjct: 469 STSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKK 528
Query: 95 K-------RNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRR 134
R+ H + R R+ PS E RR
Sbjct: 529 PLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRR 575
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 51.2 bits (121), Expect = 2e-06
Identities = 42/172 (24%), Positives = 71/172 (41%), Gaps = 18/172 (10%)
Query: 64 GHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPR-RGRE-- 120
G R R R + + + R + +R+R + +Q+ D R R RE
Sbjct: 14 GKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETE 73
Query: 121 ---DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEE 177
+RQ ++E +R + +RD+ R +R T R + +G GR+RD Q + ++
Sbjct: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG-GRERDKQTERERDR 132
Query: 178 EREFYNAR------RREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEK 223
ERE R +RE ++ D E Q R + K+ KE+
Sbjct: 133 ERERQRQRERERQRQRERKRETD-----RERQRWAEREERKKERKKERKKER 179
Score = 48.1 bits (113), Expect = 1e-05
Identities = 43/191 (22%), Positives = 77/191 (40%), Gaps = 15/191 (7%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSG 64
++ERER R+R R+ ER + HR D + R
Sbjct: 16 ETERER-DRQRERENQT----------ERENRHRQRDRHRERDRQTDREKERERQKERDR 64
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSK--SPRSKRNRSPHHSTVKVKQEREDHPRRGRE-D 121
R R R R +++ + R K + R + + + RE + + GRE D
Sbjct: 65 QR-QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
Query: 122 RQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREF 181
+Q ++E R R +R+R R +R T ER + + R ++ + + +E + +
Sbjct: 124 KQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKK 183
Query: 182 YNARRREHRQR 192
+RRE ++R
Sbjct: 184 KEEKRREDKKR 194
Score = 46.2 bits (108), Expect = 5e-05
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 20/174 (11%)
Query: 58 SEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRR 117
++ R R R R + K R+ + R ++ + ++ER+ R
Sbjct: 29 NQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRER 88
Query: 118 GRE-DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQE 176
R+ DR+ + ++E +R + +R+R+R +R ER RDR+ + + +E
Sbjct: 89 KRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERE-------RDRERERQRQRE 141
Query: 177 EEREFYNARRRE---HRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFE 227
ER+ R+RE RQR +E +E R KE++ KEK E
Sbjct: 142 RERQRQRERKRETDRERQR------WAEREE---RKKERKKERKKERKEKKKEE 186
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 11/129 (8%)
Query: 79 KKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRE-DRQHREPSEQEHRRARN 137
+++ K R K +R+R ++ R R RE DRQ E+E ++ R
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER- 62
Query: 138 SDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRRE---HRQRND 194
DR R R +R T +R Q + R R T + ++ +RE R+RE +R+RN
Sbjct: 63 -DRQRQRERETERETERQRERQRQRE-RKRQTDRERDKDRDRE----RKRETDRNRERNR 116
Query: 195 VGGGGSESQ 203
GG + Q
Sbjct: 117 KGGRERDKQ 125
Score = 35.0 bits (79), Expect = 0.12
Identities = 18/74 (24%), Positives = 31/74 (41%)
Query: 121 DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE 180
+RQ E + + +RDR R +Q N + + RDR T + +E ++E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 181 FYNARRREHRQRND 194
R+RE +
Sbjct: 62 RDRQRQRERETERE 75
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/69 (24%), Positives = 30/69 (43%)
Query: 149 QRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPR 208
++R G+ R+RD Q + + ERE + +R HR+R+ E + R
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 209 PGGNNKEKE 217
+E+E
Sbjct: 63 DRQRQRERE 71
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 50.4 bits (119), Expect = 3e-06
Identities = 73/308 (23%), Positives = 120/308 (38%), Gaps = 61/308 (19%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVV----VKQERLSPEVAPPAHRRPDHSGGSPSPPTS-- 58
+ E +R R R G+ + +K+ + SP V + DH S SP
Sbjct: 363 RQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSP-VRVKERKITDHRNVSESPNRKNE 421
Query: 59 -EPARSGHRGN-RARGVSRSPPK--------KKNKASGRRSKS---PRSKRNRSPH---- 101
E H+ N + R + R+ K KK S RSKS +SK S H
Sbjct: 422 KEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNE 481
Query: 102 ------------HSTVKVKQEREDHPRRGREDRQHREPSEQ------EHRRARNSDRDRH 143
H VK K+++ D + +E + +E S+Q EH +++ ++DR
Sbjct: 482 EKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRR 541
Query: 144 R------------GHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQ 191
HS+ RT ER S R R + + + +E++ R +E+R+
Sbjct: 542 AQSRSRECDITKGKHSYNSRT-RERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRR 600
Query: 192 RNDVGGGGSESQELVPRPG-GNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPP 250
R G S S+E PG +K++ ++ S E + + + +R K S
Sbjct: 601 R-----GRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRK 655
Query: 251 EARIPKKR 258
E +KR
Sbjct: 656 ENSESEKR 663
Score = 45.8 bits (107), Expect = 7e-05
Identities = 49/247 (19%), Positives = 91/247 (36%), Gaps = 30/247 (12%)
Query: 47 DHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVK 106
DH S+ +R++ S+ K N+ SKS R
Sbjct: 493 DHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHD--HSKSKEKDRRAQSRSRECD 550
Query: 107 VKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQR------------RTSN 154
+ + + + R RE + R+ S + R+R DRDR R + R R+
Sbjct: 551 ITKGKHSYNSRTRERSRSRDRSRRV--RSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRE 608
Query: 155 ERPGSGQGQGRDRDTQNLQAQEEEREFYNARRRE----------HRQRNDVGGGGSESQE 204
R G+ + +DR + ++ ERE +R ++ HR+ N S+
Sbjct: 609 RRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKS 668
Query: 205 LVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEAR--IPKKRWRLY 262
N++EK+ + P ++ + N + ++K E + R + K+ +
Sbjct: 669 RDHNSSNNSREKKADRDQSPFSKIKQS--SQDNELKSSMLKNKEDEKIRSSVEKENQKSK 726
Query: 263 PFKNDEV 269
+ND V
Sbjct: 727 GQENDHV 733
Score = 42.7 bits (99), Expect = 6e-04
Identities = 35/167 (20%), Positives = 71/167 (42%), Gaps = 15/167 (8%)
Query: 7 ERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHR 66
E+E R R R + P G ++R + R + + ++ ++S HR
Sbjct: 595 EQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHR 654
Query: 67 GNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHP-----RRGRED 121
+ R K ++ S S+ ++ R++SP K+KQ +D+ + +ED
Sbjct: 655 KENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFS---KIKQSSQDNELKSSMLKNKED 711
Query: 122 RQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRD 168
+ R E+E+++++ + D H H++ N++ G D D
Sbjct: 712 EKIRSSVEKENQKSKGQEND----HVHEK---NKKFDHESSPGTDED 751
Score = 38.5 bits (88), Expect = 0.011
Identities = 36/153 (23%), Positives = 66/153 (43%), Gaps = 12/153 (7%)
Query: 75 RSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQER-----EDHPRRGREDRQHREPSE 129
+SPPK K R+++ +R +P +S Q R +GR R++R PS
Sbjct: 289 KSPPKADEKE--RKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSR 346
Query: 130 QEHR-RARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRR- 187
R R R S+ H +R R SG+ + ++ + +E +R + R
Sbjct: 347 SRSRDRFRRSETPPH-WRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERK 405
Query: 188 --EHRQRNDVGGGGSESQELVPRPGGNNKEKEV 218
+HR ++ +E ++ V N+KE+++
Sbjct: 406 ITDHRNVSESPNRKNEKEKKVKDHKSNSKERDI 438
Score = 30.8 bits (68), Expect = 2.2
Identities = 42/187 (22%), Positives = 66/187 (35%), Gaps = 25/187 (13%)
Query: 57 TSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRN-RSPHHSTVKVKQ-----E 110
T E ++ + +R KKK K S + + S N + STV+ ++ E
Sbjct: 223 TEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPE 282
Query: 111 REDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRR---TSNERPGSGQG----- 162
R+ +E +E R R + + S+QRR T + R G+G
Sbjct: 283 NRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYR 342
Query: 163 -QGRDRDTQNLQAQEEEREFYNARRREHRQRNDVG-----GGGSESQELVPRPGGNNKEK 216
R R + E + +R R R G G SE E+ N+
Sbjct: 343 TPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEI-----KENQRS 397
Query: 217 EVPAKEK 223
V KE+
Sbjct: 398 PVRVKER 404
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 49.7 bits (117), Expect = 5e-06
Identities = 44/175 (25%), Positives = 77/175 (44%), Gaps = 22/175 (12%)
Query: 49 SGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRS----KSPRSKRNR------ 98
S S S TSE + N+ + + R +KKNK SG + + +SK+ +
Sbjct: 265 SSSSSSTETSESSSESESNNKEKKIQRKK-RKKNKCSGHNNSDSEEKDKSKKRKLHEELS 323
Query: 99 SPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPG 158
S HH+ K K++ R + RE S+ H + + + R HS ++R S + G
Sbjct: 324 SSHHNREKAKEK-----PRFLKHESSREDSKWSH--SDSDKKSRTHKHSPEKRGSERKEG 376
Query: 159 SGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNN 213
S + GR+ ++ + R + ++RE R+R G +S+ R G +
Sbjct: 377 SSRSHGREERSR----RSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTD 427
Score = 32.0 bits (71), Expect = 1.0
Identities = 28/131 (21%), Positives = 49/131 (37%), Gaps = 13/131 (9%)
Query: 59 EPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRG 118
E + S H +A+ R + ++ + S S K++R+ HS K ER++
Sbjct: 321 ELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEG---- 376
Query: 119 REDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEE 178
R H R+R+ + R R+ + PG Q + D + E
Sbjct: 377 -SSRSHGREERSRRSRSRSPGSYKQR---ETRKRAQRNPGEEQSRRNDSRSHGTDLYRGE 432
Query: 179 REFYNARRREH 189
+ + REH
Sbjct: 433 KMY-----REH 438
>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
Length = 1374
Score = 49.3 bits (116), Expect = 6e-06
Identities = 49/187 (26%), Positives = 68/187 (36%), Gaps = 18/187 (9%)
Query: 46 PDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKS-PRSKRNRSPH--- 101
P S P PP P + ++ PP N S P + + SPH
Sbjct: 147 PPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRH 206
Query: 102 ---HSTVKVKQEREDHPR-RGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERP 157
+ K ER R + +D +HR+ S R R+ DR R RG S RR + R
Sbjct: 207 LPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDR-RERGRSPDRRRQDSRY 265
Query: 158 GSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDV---------GGGGSESQELVPR 208
S +GR + ERE R R++R+ + G S +VP
Sbjct: 266 RSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGLSVVPE 325
Query: 209 PGGNNKE 215
P G E
Sbjct: 326 PAGCTPE 332
Score = 36.2 bits (82), Expect = 0.053
Identities = 37/127 (29%), Positives = 48/127 (37%), Gaps = 41/127 (32%)
Query: 32 ERLSPEVAP--PAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRS 89
ER SPE HR DHS G RG R R + R R
Sbjct: 218 ERRSPERLKHYDDHRHRDHSHG--------------RGERHRSLDRR----------ERG 253
Query: 90 KSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQ 149
+SP +R S + S RGR +HR + R+R +R+RHR ++
Sbjct: 254 RSPDRRRQDSRYRSDYD----------RGRTPSRHRS-----YERSRERERERHRHRDNR 298
Query: 150 RRTSNER 156
R S ER
Sbjct: 299 RSPSLER 305
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 48.9 bits (115), Expect = 8e-06
Identities = 53/249 (21%), Positives = 83/249 (33%), Gaps = 28/249 (11%)
Query: 2 KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHS------------ 49
K+ E ER + +D L G + K+E+ P A A + P +
Sbjct: 212 KSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKA--AFKEPKMALKETKLESTSPK 269
Query: 50 GGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQ 109
GG P PP P S R A S K+K +S +P + S S K
Sbjct: 270 GGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKP 329
Query: 110 EREDHPRRGREDRQHREPSEQ----EHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGR 165
++ RG + + EP E E + + D + S Q SN S
Sbjct: 330 AKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDS 389
Query: 166 DRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVP----------RPGGNNKE 215
D + +Q R + E +D G + + P N+ +
Sbjct: 390 DFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSAD 449
Query: 216 KEVPAKEKP 224
+P++E P
Sbjct: 450 SSLPSREPP 458
Score = 36.6 bits (83), Expect = 0.041
Identities = 44/228 (19%), Positives = 79/228 (34%), Gaps = 14/228 (6%)
Query: 5 KSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSG 64
K++ GS+ +++ V K+ R P R+ S S E A+S
Sbjct: 174 KTKPSHGSKDANKESSKTSKPHKVTKEHRERP-------RKDSESKSSSKELEREQAKSS 226
Query: 65 HRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQH 124
+R G R P ++K K P+ + ST P R +
Sbjct: 227 KDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKR 286
Query: 125 R----EPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDT---QNLQAQEE 177
P ++ ++S + RTS+ S + +D+ + + ++A+ E
Sbjct: 287 PATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESE 346
Query: 178 EREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPS 225
RE A E D SES + P ++ + + +PS
Sbjct: 347 PREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPS 394
Score = 34.3 bits (77), Expect = 0.20
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 7/81 (8%)
Query: 76 SPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRA 135
S PKK + G + + S + PH T ++H R R+D + + S++ R
Sbjct: 170 SDPKKTKPSHGSKDANKESSKTSKPHKVT-------KEHRERPRKDSESKSSSKELEREQ 222
Query: 136 RNSDRDRHRGHSHQRRTSNER 156
S +D R R E+
Sbjct: 223 AKSSKDTSRKLGEGRLPKEEK 243
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 48.9 bits (115), Expect = 8e-06
Identities = 55/226 (24%), Positives = 82/226 (36%), Gaps = 51/226 (22%)
Query: 37 EVAPPAHRRPDHSGGSPSPP-----------TSEPARSGHRGNRARGVSRS-----PPKK 80
E+ PP+ R S S T RS R +R S S P ++
Sbjct: 985 ELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQ 1044
Query: 81 KNKASGRRSKSPRSKRNRSPHHSTVKVKQERE-----DHPRR---------GREDRQHRE 126
++KA RRS S RS K K H RR G +H E
Sbjct: 1045 RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYE 1104
Query: 127 PSEQEHRRARNSDRDRHRG----------HSHQRRTSNERPGSGQGQGRDRDTQNLQAQE 176
+++ RR+ + R R H HQR S+ERP + RD + +++
Sbjct: 1105 SRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRS 1164
Query: 177 EEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKE 222
E R REHR+ S+E P+ ++ E++ +E
Sbjct: 1165 PSSEH---RAREHRR--------PRSREKWPQTRSHSPERKGAVRE 1199
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/149 (24%), Positives = 53/149 (35%), Gaps = 14/149 (9%)
Query: 56 PTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHP 115
P + P+ + R V PP + S RS+ ++ S H + E
Sbjct: 967 PEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRD 1026
Query: 116 RRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQ 175
R R PS E R R + + R S R +S ER + + + R
Sbjct: 1027 RSSRS----ASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSR-------- 1074
Query: 176 EEEREFYNARRREHRQRNDVGGGGSESQE 204
E R + RR R R+ G GS S E
Sbjct: 1075 EHRRGPWGHSRRTSRSRS--GSPGSSSYE 1101
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,842,912
Number of Sequences: 37866
Number of extensions: 1079707
Number of successful extensions: 14355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 284
Number of HSP's successfully gapped in prelim test: 560
Number of HSP's that attempted gapping in prelim test: 8284
Number of HSP's gapped (non-prelim): 3844
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.