BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21314690 N-glycanase 1 isoform 1 [Homo sapiens] (654 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21314690 N-glycanase 1 isoform 1 [Homo sapiens] 1333 0.0 gi|223941803 N-glycanase 1 isoform 3 [Homo sapiens] 1254 0.0 gi|223941798 N-glycanase 1 isoform 2 [Homo sapiens] 1209 0.0 gi|223941808 N-glycanase 1 isoform 4 [Homo sapiens] 1102 0.0 gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein... 38 0.034 gi|13376854 UBX domain protein 6 [Homo sapiens] 37 0.044 gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens] 36 0.13 gi|46276885 WD repeat domain 78 isoform 2 [Homo sapiens] 36 0.13 gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 35 0.17 gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 35 0.17 gi|4502613 cyclin A [Homo sapiens] 35 0.28 gi|189011568 adenomatous polyposis coli [Homo sapiens] 34 0.37 gi|189011566 adenomatous polyposis coli [Homo sapiens] 34 0.37 gi|53759122 adenomatous polyposis coli [Homo sapiens] 34 0.37 gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens] 34 0.49 gi|50345997 E1A binding protein p300 [Homo sapiens] 33 0.63 gi|224809302 xeroderma pigmentosum, complementation group C isof... 33 0.63 gi|224809295 xeroderma pigmentosum, complementation group C isof... 33 0.63 gi|33946327 nucleoporin 214kDa [Homo sapiens] 33 1.1 gi|11067749 bromodomain containing protein 3 [Homo sapiens] 33 1.1 gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens] 32 1.8 gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ... 32 1.8 gi|221139926 NHS-like 1 [Homo sapiens] 31 4.1 gi|23199971 T-cell activation Rho GTPase-activating protein isof... 31 4.1 gi|21314774 T-cell activation Rho GTPase-activating protein isof... 31 4.1 gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 30 5.4 gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 30 7.0 gi|16753207 ubiquilin 2 [Homo sapiens] 30 7.0 gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 30 7.0 gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 30 7.0 >gi|21314690 N-glycanase 1 isoform 1 [Homo sapiens] Length = 654 Score = 1333 bits (3450), Expect = 0.0 Identities = 654/654 (100%), Positives = 654/654 (100%) Query: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA Sbjct: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60 Query: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH Sbjct: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120 Query: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ Sbjct: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180 Query: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE Sbjct: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240 Query: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK Sbjct: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300 Query: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD 360 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD Sbjct: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD 360 Query: 361 KPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQ 420 KPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQ Sbjct: 361 KPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQ 420 Query: 421 RQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETL 480 RQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETL Sbjct: 421 RQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETL 480 Query: 481 FIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVYL 540 FIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVYL Sbjct: 481 FIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVYL 540 Query: 541 ARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSL 600 ARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSL Sbjct: 541 ARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSL 600 Query: 601 HSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL 654 HSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL Sbjct: 601 HSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL 654 >gi|223941803 N-glycanase 1 isoform 3 [Homo sapiens] Length = 612 Score = 1254 bits (3245), Expect = 0.0 Identities = 611/612 (99%), Positives = 612/612 (100%) Query: 43 LRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 102 +RNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR Sbjct: 1 MRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 60 Query: 103 DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 162 DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA Sbjct: 61 DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 120 Query: 163 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN Sbjct: 121 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180 Query: 223 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 282 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY Sbjct: 181 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 240 Query: 283 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 342 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY Sbjct: 241 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 300 Query: 343 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR 402 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR Sbjct: 301 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR 360 Query: 403 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS 462 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS Sbjct: 361 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS 420 Query: 463 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW 522 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW Sbjct: 421 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW 480 Query: 523 KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE 582 KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE Sbjct: 481 KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE 540 Query: 583 WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE 642 WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE Sbjct: 541 WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE 600 Query: 643 NCLEIIIKFSDL 654 NCLEIIIKFSDL Sbjct: 601 NCLEIIIKFSDL 612 >gi|223941798 N-glycanase 1 isoform 2 [Homo sapiens] Length = 636 Score = 1209 bits (3127), Expect = 0.0 Identities = 614/655 (93%), Positives = 617/655 (94%), Gaps = 20/655 (3%) Query: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA Sbjct: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60 Query: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH Sbjct: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120 Query: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ Sbjct: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180 Query: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE Sbjct: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240 Query: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK Sbjct: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300 Query: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD 360 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYT+ QR L Sbjct: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTE----------LQRTLSLKL------ 344 Query: 361 KPLLYEIGWGKKLSYVIAFSK-DEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK 419 L EI GK + K +VVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK Sbjct: 345 -TTLKEI--GKTFLRISKRQKLIQVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK 401 Query: 420 QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET 479 QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET Sbjct: 402 QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET 461 Query: 480 LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVY 539 LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVY Sbjct: 462 LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVY 521 Query: 540 LARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNS 599 LARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNS Sbjct: 522 LARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNS 581 Query: 600 LHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL 654 LHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL Sbjct: 582 LHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL 636 >gi|223941808 N-glycanase 1 isoform 4 [Homo sapiens] Length = 558 Score = 1102 bits (2849), Expect = 0.0 Identities = 537/538 (99%), Positives = 538/538 (100%) Query: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA Sbjct: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60 Query: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH Sbjct: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120 Query: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ Sbjct: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180 Query: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE Sbjct: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240 Query: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK Sbjct: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300 Query: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD 360 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD Sbjct: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD 360 Query: 361 KPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQ 420 KPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQ Sbjct: 361 KPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQ 420 Query: 421 RQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETL 480 RQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETL Sbjct: 421 RQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETL 480 Query: 481 FIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMV 538 FIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHM+ Sbjct: 481 FIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMI 538 >gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein [Homo sapiens] Length = 614 Score = 37.7 bits (86), Expect = 0.034 Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Query: 419 KQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKE 478 +Q+Q+ + K++LQ++ E++ +SP+ KP E +G+V V L R+ Sbjct: 266 RQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRES 325 Query: 479 TLFIPCE--NEKISKQLHLCYNIVKDRYVRVSN 509 + CE E+++ + + I+K ++ N Sbjct: 326 MWDLSCETVREQLTNSIRKQWRILKSHVEKLDN 358 >gi|13376854 UBX domain protein 6 [Homo sapiens] Length = 441 Score = 37.4 bits (85), Expect = 0.044 Identities = 17/45 (37%), Positives = 26/45 (57%) Query: 38 YADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEE 82 Y DNI +P +EKYR I++ N F R+ + G E +GF++ Sbjct: 181 YLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQK 225 >gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens] Length = 848 Score = 35.8 bits (81), Expect = 0.13 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 17/116 (14%) Query: 113 LDGSNKSHKVKSSQQPAASTQLPTTPSS-----NPSGLNQHTRNRQGQSSDPPSASTVAA 167 L G+ K K+ +SQ+ + ++ ++ S NPS L Q TR+ G S+ S S+V+A Sbjct: 135 LTGTAKPSKLLTSQEGSLGSEFISSYSLYQNTINPSTLGQFTRSVLGSST--VSKSSVSA 192 Query: 168 DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINI 223 +I E L E P+ + + L ++ R + EK+ L+K I I Sbjct: 193 SESIAEDL----------EEPSYKRERLTSFTDLQVIRAAPEKIVTKEDLEKNIEI 238 >gi|46276885 WD repeat domain 78 isoform 2 [Homo sapiens] Length = 545 Score = 35.8 bits (81), Expect = 0.13 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 17/116 (14%) Query: 113 LDGSNKSHKVKSSQQPAASTQLPTTPSS-----NPSGLNQHTRNRQGQSSDPPSASTVAA 167 L G+ K K+ +SQ+ + ++ ++ S NPS L Q TR+ G S+ S S+V+A Sbjct: 135 LTGTAKPSKLLTSQEGSLGSEFISSYSLYQNTINPSTLGQFTRSVLGSST--VSKSSVSA 192 Query: 168 DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINI 223 +I E L E P+ + + L ++ R + EK+ L+K I I Sbjct: 193 SESIAEDL----------EEPSYKRERLTSFTDLQVIRAAPEKIVTKEDLEKNIEI 238 >gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sapiens] Length = 1690 Score = 35.4 bits (80), Expect = 0.17 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 9/129 (6%) Query: 332 DYTDHVWT---EVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVT 388 D T H+W + PS+ R+LH + + +KPL + GK S K E V+ Sbjct: 1460 DETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVK---GKDSSEKKRKRKLEKVEQL 1516 Query: 389 WRYSCKHEEVIARRTKVKEALLR---DTINGLNKQRQLFLSENRRKELLQRIIVELVEFI 445 + + + + + K ++ L+ D LNK + E RK+ ++ VE + Sbjct: 1517 FGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEERKKKKEKAAAAKVELV 1576 Query: 446 SPKTPKPGE 454 T K E Sbjct: 1577 KESTEKKRE 1585 >gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sapiens] Length = 1641 Score = 35.4 bits (80), Expect = 0.17 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 9/129 (6%) Query: 332 DYTDHVWT---EVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVT 388 D T H+W + PS+ R+LH + + +KPL + GK S K E V+ Sbjct: 1465 DETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVK---GKDSSEKKRKRKLEKVEQL 1521 Query: 389 WRYSCKHEEVIARRTKVKEALLR---DTINGLNKQRQLFLSENRRKELLQRIIVELVEFI 445 + + + + + K ++ L+ D LNK + E RK+ ++ VE + Sbjct: 1522 FGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEERKKKKEKAAAAKVELV 1581 Query: 446 SPKTPKPGE 454 T K E Sbjct: 1582 KESTEKKRE 1590 >gi|4502613 cyclin A [Homo sapiens] Length = 432 Score = 34.7 bits (78), Expect = 0.28 Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 15/118 (12%) Query: 104 LIAIERSSRLDGSNKSHKVKSS--QQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPS 161 L+A+++++ + + K++ QQP L S NP GL Q R P Sbjct: 18 LLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQR---------PK 68 Query: 162 ASTVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDK 219 VA L+ L N +HV V A ++ I V E ++++Q+K + ++K+++ Sbjct: 69 TRRVAP----LKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIER 122 >gi|189011568 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%) Query: 76 FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 135 + + + E + H+ P S L+ D+ + ++ S + S + ++ ++S++ Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218 Query: 136 TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 177 +TPSSN NQ H + Q +S P A+T S E +Q+ Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261 >gi|189011566 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%) Query: 76 FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 135 + + + E + H+ P S L+ D+ + ++ S + S + ++ ++S++ Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218 Query: 136 TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 177 +TPSSN NQ H + Q +S P A+T S E +Q+ Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261 >gi|53759122 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%) Query: 76 FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 135 + + + E + H+ P S L+ D+ + ++ S + S + ++ ++S++ Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218 Query: 136 TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 177 +TPSSN NQ H + Q +S P A+T S E +Q+ Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261 >gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens] Length = 298 Score = 33.9 bits (76), Expect = 0.49 Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 15/138 (10%) Query: 117 NKSHKVKSSQQPAASTQLPTTP--------SSNPSGLNQHTRNRQGQSSDPPSASTVAA- 167 N + K+ AST LP +P S+ PS +QH R Q S +PP+ A Sbjct: 4 NTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPSPAP 63 Query: 168 -----DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222 +S+ E + V++ +P + + +LA + + +R E+L ++ + Sbjct: 64 DDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGE-DVYERTLT 122 Query: 223 ISDEDFLLLELLHWFKEE 240 + ED L+ + W E+ Sbjct: 123 VDGEDTTLVVVDTWEAEK 140 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 33.5 bits (75), Expect = 0.63 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 10/114 (8%) Query: 123 KSSQQPAASTQLPTTPSSNP---SGLNQHTRNRQGQSSDPPSASTVAADSAIL------- 172 +S Q AAS PT P P + L+Q + +GQ S+PPS S+ +S + Sbjct: 915 RSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQ 974 Query: 173 EVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDE 226 EV V E Q + ++ V++ K +S E R+ +L I ++ Sbjct: 975 EVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEED 1028 >gi|224809302 xeroderma pigmentosum, complementation group C isoform 2 [Homo sapiens] Length = 903 Score = 33.5 bits (75), Expect = 0.63 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 338 WTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDE-VVDVTWRY 391 W EV+ +++W+ D V +PL K ++YV+ D V DVT RY Sbjct: 494 WLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRY 548 >gi|224809295 xeroderma pigmentosum, complementation group C isoform 1 [Homo sapiens] Length = 940 Score = 33.5 bits (75), Expect = 0.63 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 338 WTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDE-VVDVTWRY 391 W EV+ +++W+ D V +PL K ++YV+ D V DVT RY Sbjct: 531 WLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRY 585 >gi|33946327 nucleoporin 214kDa [Homo sapiens] Length = 2090 Score = 32.7 bits (73), Expect = 1.1 Identities = 40/162 (24%), Positives = 62/162 (38%), Gaps = 21/162 (12%) Query: 8 SSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLP 67 SS G + P+ + +++P + + ++ ++ P R + TA ST Sbjct: 1256 SSGGGSKPSYEAIPESSPPSGITSA------SNTTPGEPAASSSRPVAPSGTALSTTSSK 1309 Query: 68 VRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQ 127 + L E L+FP + E L L R + D S K K+S Sbjct: 1310 LETPPSKLGE---------LLFPSSLAGETLGSFSGL----RVGQADDSTKPTN-KASST 1355 Query: 128 PAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADS 169 STQ PT S PSG N G+ ++PP S+ S Sbjct: 1356 SLTSTQ-PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTS 1396 >gi|11067749 bromodomain containing protein 3 [Homo sapiens] Length = 726 Score = 32.7 bits (73), Expect = 1.1 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Query: 96 EQLQKIRDLIAIERSSRLDG--SNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQ 153 +Q K ++ +A E+ L+ + S ++ SS++PA + + PS PS L+ + + Sbjct: 651 KQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSES 710 Query: 154 GQSSDPPSAS 163 G SS S+S Sbjct: 711 GSSSSSGSSS 720 Score = 31.2 bits (69), Expect = 3.1 Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 123 KSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQHV 182 K +P + LP + S + +R+ + SSD S+ + + L LQ ++ Sbjct: 414 KMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLK-- 471 Query: 183 LVYENPALQEKALACIPVQELKRKSQEKLSRARKLDK 219 V+E A AL+ PV + K+K ++K +K DK Sbjct: 472 AVHEQLA----ALSQAPVNKPKKKKEKKEKEKKKKDK 504 >gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens] Length = 144 Score = 32.0 bits (71), Expect = 1.8 Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 26/112 (23%) Query: 53 SIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQL-QKIRDLIAIERSS 111 S+R+ N++ ++ A++ E + ++HL++ + VE L ++I++LI E++S Sbjct: 36 SVRLDNSSSGASVV----AIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELI--EKNS 89 Query: 112 RLDGSNKSHKVKSSQ-------------------QPAASTQLPTTPSSNPSG 144 +L+ N K +S QP +TQ P P+S SG Sbjct: 90 QLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSG 141 >gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 [Homo sapiens] Length = 1461 Score = 32.0 bits (71), Expect = 1.8 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%) Query: 78 MGFEEGETHLIFPKK-ASVEQLQKIRDLIAIERSSRLDGSNK----SHKVKSSQQPAAST 132 MG EE ++ + +K A+ E + RD+ +E S D +K K K +++ A ST Sbjct: 341 MGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVST 400 Query: 133 QLPTTPSSNPSGLNQHTRNRQGQSSDPP 160 +PT P+ N S + T ++ PP Sbjct: 401 SVPTKPTENISKASSCTPVPVTMTATPP 428 >gi|221139926 NHS-like 1 [Homo sapiens] Length = 1606 Score = 30.8 bits (68), Expect = 4.1 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 91 KKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAAST-QLPTTPSSNPSGLNQHT 149 ++ + EQ + ++ S+ L N +++++S QPA+ T LPT S+ G + Sbjct: 1094 ERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSA 1153 Query: 150 RNRQGQSSDPPSASTVAADSA 170 R G S P A + A Sbjct: 1154 AERGGPVSRSPGAPSAGEAEA 1174 >gi|23199971 T-cell activation Rho GTPase-activating protein isoform a [Homo sapiens] Length = 553 Score = 30.8 bits (68), Expect = 4.1 Identities = 31/149 (20%), Positives = 61/149 (40%), Gaps = 6/149 (4%) Query: 20 LCQNTPETFLEASKLLLTYADNILRNPNDEK--YRSIRIGNTAFSTRLLPVRGAVECLFE 77 + +N+ +++S L + N+L ND+ + + + N T V ++ FE Sbjct: 41 ISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTL---VEFLIDNCFE 97 Query: 78 MGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTT 137 + E H S+E D+ ++ S D ++ + SS ++ ++ P Sbjct: 98 IFGENIPVHSSITSDDSLEHTDS-SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQV 156 Query: 138 PSSNPSGLNQHTRNRQGQSSDPPSASTVA 166 P + +GL+ + S P STVA Sbjct: 157 PMATAAGLDSAGPQDAREVSPEPIVSTVA 185 >gi|21314774 T-cell activation Rho GTPase-activating protein isoform b [Homo sapiens] Length = 731 Score = 30.8 bits (68), Expect = 4.1 Identities = 31/149 (20%), Positives = 61/149 (40%), Gaps = 6/149 (4%) Query: 20 LCQNTPETFLEASKLLLTYADNILRNPNDEK--YRSIRIGNTAFSTRLLPVRGAVECLFE 77 + +N+ +++S L + N+L ND+ + + + N T V ++ FE Sbjct: 219 ISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTL---VEFLIDNCFE 275 Query: 78 MGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTT 137 + E H S+E D+ ++ S D ++ + SS ++ ++ P Sbjct: 276 IFGENIPVHSSITSDDSLEHTDS-SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQV 334 Query: 138 PSSNPSGLNQHTRNRQGQSSDPPSASTVA 166 P + +GL+ + S P STVA Sbjct: 335 PMATAAGLDSAGPQDAREVSPEPIVSTVA 363 >gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] Length = 3664 Score = 30.4 bits (67), Expect = 5.4 Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 7/125 (5%) Query: 107 IERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVA 166 +ER RL K K K+ +Q +PSS S +Q Q P S + ++ Sbjct: 802 VERERRLIRKEKVEKDKTDKQKRKGKV--HSPSSQSSETDQENEREQSPEK-PRSCNKLS 858 Query: 167 ADSAILEVLQSN----IQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222 + A E + N + V++ + K + PV++LK K ++ LD+ + Sbjct: 859 REKADKEGIAKNRLELMPCVVLTRVKEKEGKVIDHTPVEKLKAKLDNDTVKSSALDQKLQ 918 Query: 223 ISDED 227 +S + Sbjct: 919 VSQTE 923 >gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] Length = 710 Score = 30.0 bits (66), Expect = 7.0 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 81 EEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSS 140 E ++ + P+K S +++ + + + ++R+ G KS V S +QPA+ T T S+ Sbjct: 119 EGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSA 178 Query: 141 NPSGLNQHTRNRQG 154 LN T + G Sbjct: 179 ----LNTATEIKDG 188 >gi|16753207 ubiquilin 2 [Homo sapiens] Length = 624 Score = 30.0 bits (66), Expect = 7.0 Identities = 48/190 (25%), Positives = 75/190 (39%), Gaps = 14/190 (7%) Query: 13 ASPAVAELCQNTPE-TFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGA 71 A+P + +L Q PE + L + ++ I RNP + +R + A S L + G Sbjct: 207 ANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQ-EMMRNQDLALSN-LESIPGG 264 Query: 72 VECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAAS 131 L M + E L A+ EQ SS +G+ S P Sbjct: 265 YNALRRMYTDIQEPML----NAAQEQFGGNPFASVGSSSSSGEGTQPSRTENRDPLPNPW 320 Query: 132 TQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEV-----LQSNIQHVLVYE 186 P T SS + T + G SS + +TVAA + + + +QS +Q + E Sbjct: 321 APPPATQSSATTSTTTSTGSGSGNSSSNATGNTVAAANYVASIFSTPGMQSLLQQIT--E 378 Query: 187 NPALQEKALA 196 NP L + L+ Sbjct: 379 NPQLIQNMLS 388 >gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] Length = 1073 Score = 30.0 bits (66), Expect = 7.0 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 22/94 (23%) Query: 71 AVECLFEMGFEEGETHLIFPKKASVEQL-QKIRDLIAIERSSRLDGSNKSHKVKSSQ--- 126 A++ E + ++HL++ + VE L ++I++LI E++S+L+ N K +S Sbjct: 979 AIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELI--EKNSQLEQENNLLKTLASPEQL 1036 Query: 127 ----------------QPAASTQLPTTPSSNPSG 144 QP +TQ P P+S SG Sbjct: 1037 AQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSG 1070 >gi|124517695 ankyrin repeat domain 36B [Homo sapiens] Length = 1121 Score = 30.0 bits (66), Expect = 7.0 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 81 EEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSS 140 E ++ + P+K S +++ + + + ++R+ G KS V S +QPA+ T T S+ Sbjct: 84 EGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSA 143 Query: 141 NPSGLNQHTRNRQG 154 LN T + G Sbjct: 144 ----LNTATEIKDG 153 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,080,269 Number of Sequences: 37866 Number of extensions: 1139173 Number of successful extensions: 3968 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 7 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 3941 Number of HSP's gapped (non-prelim): 52 length of query: 654 length of database: 18,247,518 effective HSP length: 109 effective length of query: 545 effective length of database: 14,120,124 effective search space: 7695467580 effective search space used: 7695467580 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.