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Search of human proteins with 212276104
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|212276104 leucine rich repeat (in FLII) interacting protein
1 isoform 5 [Homo sapiens]
(752 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|212276104 leucine rich repeat (in FLII) interacting protein 1... 1488 0.0
gi|212276070 leucine rich repeat (in FLII) interacting protein 1... 1472 0.0
gi|212276096 leucine rich repeat (in FLII) interacting protein 1... 1458 0.0
gi|212276088 leucine rich repeat (in FLII) interacting protein 1... 463 e-130
gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 268 1e-71
gi|8923224 leucine rich repeat (in FLII) interacting protein 2 i... 231 2e-60
gi|197276647 leucine rich repeat (in FLII) interacting protein 2... 220 4e-57
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i... 150 4e-36
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 79 2e-14
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 70 7e-12
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 68 3e-11
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 60 1e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 58 3e-08
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 58 3e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 6e-08
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 56 1e-07
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 56 1e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 55 2e-07
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 55 2e-07
gi|157738619 smoothelin-like 1 [Homo sapiens] 55 3e-07
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 54 4e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 53 9e-07
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 53 9e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 52 2e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 52 2e-06
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 52 3e-06
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 52 3e-06
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 52 3e-06
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 51 3e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 51 3e-06
>gi|212276104 leucine rich repeat (in FLII) interacting protein 1
isoform 5 [Homo sapiens]
Length = 752
Score = 1488 bits (3853), Expect = 0.0
Identities = 752/752 (100%), Positives = 752/752 (100%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV
Sbjct: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE
Sbjct: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL
Sbjct: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
Query: 241 GRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTA 300
GRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTA
Sbjct: 241 GRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTA 300
Query: 301 PFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDG 360
PFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDG
Sbjct: 301 PFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDG 360
Query: 361 GNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEF 420
GNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEF
Sbjct: 361 GNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEF 420
Query: 421 TNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS 480
TNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS
Sbjct: 421 TNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS 480
Query: 481 TVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELT 540
TVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELT
Sbjct: 481 TVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELT 540
Query: 541 YQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKL 600
YQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKL
Sbjct: 541 YQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKL 600
Query: 601 DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPA 660
DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPA
Sbjct: 601 DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPA 660
Query: 661 EPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSA 720
EPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSA
Sbjct: 661 EPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSA 720
Query: 721 PGREPGHFNPESREDTRGGNEKGKSKEDCTMS 752
PGREPGHFNPESREDTRGGNEKGKSKEDCTMS
Sbjct: 721 PGREPGHFNPESREDTRGGNEKGKSKEDCTMS 752
>gi|212276070 leucine rich repeat (in FLII) interacting protein 1
isoform 4 [Homo sapiens]
Length = 784
Score = 1472 bits (3810), Expect = 0.0
Identities = 752/784 (95%), Positives = 752/784 (95%), Gaps = 32/784 (4%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- 51
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
Query: 52 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 88
VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
Query: 89 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 148
GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE
Sbjct: 121 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 180
Query: 149 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 208
QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE
Sbjct: 181 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 240
Query: 209 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 268
TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE
Sbjct: 241 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 300
Query: 269 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN 328
QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN
Sbjct: 301 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN 360
Query: 329 TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG 388
TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG
Sbjct: 361 TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG 420
Query: 389 HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 448
HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE
Sbjct: 421 HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 480
Query: 449 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 508
ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS
Sbjct: 481 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 540
Query: 509 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN 568
SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN
Sbjct: 541 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN 600
Query: 569 EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV 628
EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV
Sbjct: 601 EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV 660
Query: 629 QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA 688
QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA
Sbjct: 661 QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA 720
Query: 689 ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED 748
ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED
Sbjct: 721 ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED 780
Query: 749 CTMS 752
CTMS
Sbjct: 781 CTMS 784
>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
isoform 3 [Homo sapiens]
Length = 808
Score = 1458 bits (3775), Expect = 0.0
Identities = 752/808 (93%), Positives = 752/808 (93%), Gaps = 56/808 (6%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- 51
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
Query: 52 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 88
VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
Query: 89 GDTSISIDTEASIREIK------------------------DSLAEVEEKYKKAMVSNAQ 124
GDTSISIDTEASIREIK DSLAEVEEKYKKAMVSNAQ
Sbjct: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
Query: 125 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 184
LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA
Sbjct: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
Query: 185 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 244
LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS
Sbjct: 241 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 300
Query: 245 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 304
EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG
Sbjct: 301 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 360
Query: 305 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 364
TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT
Sbjct: 361 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 420
Query: 365 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 424
ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE
Sbjct: 421 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 480
Query: 425 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 484
AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT
Sbjct: 481 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 540
Query: 485 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 544
QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT
Sbjct: 541 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 600
Query: 545 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 604
DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG
Sbjct: 601 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 660
Query: 605 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 664
DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS
Sbjct: 661 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 720
Query: 665 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 724
EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE
Sbjct: 721 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 780
Query: 725 PGHFNPESREDTRGGNEKGKSKEDCTMS 752
PGHFNPESREDTRGGNEKGKSKEDCTMS
Sbjct: 781 PGHFNPESREDTRGGNEKGKSKEDCTMS 808
>gi|212276088 leucine rich repeat (in FLII) interacting protein 1
isoform 2 [Homo sapiens]
Length = 394
Score = 463 bits (1192), Expect = e-130
Identities = 256/345 (74%), Positives = 276/345 (80%), Gaps = 12/345 (3%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV
Sbjct: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE
Sbjct: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL
Sbjct: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
Query: 241 G---------RASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTE 291
R +E ++ + +R+ + + + +D +++ D+ V +
Sbjct: 241 DIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDAN 300
Query: 292 DQKSSEDTAPFLGTLAGATYEEQV---QSQILESSSLPENTVQVE 333
Q S E+ V +SQ+ S EN ++E
Sbjct: 301 RQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIE 345
Score = 33.5 bits (75), Expect = 0.75
Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Query: 405 PQELETSTGHSLEKEFTNQEAAE--PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 462
P+ + + K EA E KE+ EV + E++ E G R+ +
Sbjct: 17 PEAQKLAEARLAAKRAARAEAREIRMKELERQQKEV-EERPEKDFTEKGSRNMPGLSAAT 75
Query: 463 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 522
S GT ++DT+ ++K+ E ++ +A+ S N + N+K
Sbjct: 76 LASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS------NAQLDNEK 129
Query: 523 KKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRK 561
V+TLKD+ EL Q + S + EE+ K +R+
Sbjct: 130 TNFMYQVDTLKDMLLELEEQLAE-SRRQYEEKNKEFERE 167
>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
isoform 1 [Homo sapiens]
Length = 640
Score = 268 bits (686), Expect = 1e-71
Identities = 162/261 (62%), Positives = 181/261 (69%), Gaps = 36/261 (13%)
Query: 47 RQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK- 105
R VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK
Sbjct: 207 RASPVVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKE 266
Query: 106 -----------------------DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 142
DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM
Sbjct: 267 LNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 326
Query: 143 LLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSE 202
LLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE+ + +
Sbjct: 327 LLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEEIRQLQQKQ 386
Query: 203 IATNGETSDTLNNVGYQ----GPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGK 258
++ E SD + ++ G + KE ++++S D R V +K E+ K
Sbjct: 387 ASSIREISDLQETIEWKDKKIGALERQKEFFDSVRSERDDL--REEVVMLKEEL----KK 440
Query: 259 REILHNTE--KEQHTEDTVKD 277
I+ N+E T DT+ +
Sbjct: 441 HGIILNSEIATNGETSDTLNN 461
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/48 (70%), Positives = 40/48 (83%), Gaps = 1/48 (2%)
Query: 11 EIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEK 58
E D L+ A++ AEARLAAKRAARAEAREIRMKELERQQKE+ + +K
Sbjct: 22 EDDALNQIARE-AEARLAAKRAARAEAREIRMKELERQQKEIYQVQKK 68
Score = 34.3 bits (77), Expect = 0.44
Identities = 33/154 (21%), Positives = 63/154 (40%), Gaps = 4/154 (2%)
Query: 426 AEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQ 485
A + A ++ V + E++ E G R+ + S GT ++DT+
Sbjct: 199 ASSRASSARASPVVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTE 258
Query: 486 NEPLDMKEPDEEK---SDQQGEALDS-SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTY 541
++KE +E K D +G+ + + K + + K KK+ V L + K Y
Sbjct: 259 ASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMY 318
Query: 542 QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPK 575
Q L ++ E + + + + E +N+ E K
Sbjct: 319 QVDTLKDMLLELEEQLAESRRQYEEKNKEFEREK 352
>gi|8923224 leucine rich repeat (in FLII) interacting protein 2
isoform 2 [Homo sapiens]
Length = 400
Score = 231 bits (589), Expect = 2e-60
Identities = 145/338 (42%), Positives = 215/338 (63%), Gaps = 17/338 (5%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNM 68
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE++E+ +K + E +R
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKELDEKSDKQYAENYTRPS 76
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNE 128
SA+ L G SSRRGSGDTS ID + S+ E+++SL+EVEEKYKKAMVSNAQLDNE
Sbjct: 77 SRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRESLSEVEEKYKKAMVSNAQLDNE 136
Query: 129 KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQR 188
K N +YQVDTLKD++ E EEQ+AE R+ EEK+KE ER+KH S+LQ + E+KE L+QR
Sbjct: 137 KNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQR 196
Query: 189 EEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG-RASEVE 247
+E++EKHG+++ + NG+ S + T +++E L+S G+G L R ++
Sbjct: 197 DELIEKHGLVIIPDGTPNGDVS---HEPVAGAITVVSQEAAQVLESAGEGPLDVRLRKLA 253
Query: 248 -VKNEIVANVGKREILHNTEKEQ--HTEDTVKDCVDIEVFPAGENTEDQK-SSEDTAPFL 303
K E+++ + K ++ E+++ + TV D ++ + E Q+ ++ + +
Sbjct: 254 GEKEELLSQIRKLKLQLEEERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQISEYK 313
Query: 304 GTLAGA-----TYEEQV---QSQILESSSLPENTVQVE 333
L+ A T E+ + + Q+L + EN +VE
Sbjct: 314 FKLSKAEQDITTLEQSISRLEGQVLRYKTAAENAEKVE 351
Score = 32.3 bits (72), Expect = 1.7
Identities = 42/183 (22%), Positives = 69/183 (37%), Gaps = 24/183 (13%)
Query: 454 DEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQN----EPLDMKEPDEEKSDQQGEALDSS 509
DEK K + N AT P + ++ + + +PD S+ + E+L
Sbjct: 61 DEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELR-ESLSEV 119
Query: 510 QKKTK-----NKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEE----------- 553
++K K N + N+K V+TLKDV +E Q + EE+
Sbjct: 120 EEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMC 179
Query: 554 ---QVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTA 610
Q K + K + ++E+ E I + + N D P + QE V +
Sbjct: 180 SVLQHKMEELKEGLRQRDELIEKHGLVIIPDGTPNGDVSHEPVAGAITVVSQEAAQVLES 239
Query: 611 AEE 613
A E
Sbjct: 240 AGE 242
>gi|197276647 leucine rich repeat (in FLII) interacting protein 2
isoform 3 [Homo sapiens]
Length = 424
Score = 220 bits (560), Expect = 4e-57
Identities = 146/362 (40%), Positives = 216/362 (59%), Gaps = 41/362 (11%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNM 68
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE++E+ +K + E +R
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKELDEKSDKQYAENYTRPS 76
Query: 69 PGLSAATLASLGGTSSRRGSGDTSISIDTEASI------------------------REI 104
SA+ L G SSRRGSGDTS ID + S+ +E+
Sbjct: 77 SRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDLKDQIQDVEGRYMQGLKEL 136
Query: 105 KDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEF 164
K+SL+EVEEKYKKAMVSNAQLDNEK N +YQVDTLKD++ E EEQ+AE R+ EEK+KE
Sbjct: 137 KESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKEL 196
Query: 165 EREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKM 224
ER+KH S+LQ + E+KE L+QR+E++EKHG+++ + NG+ S + T +
Sbjct: 197 ERQKHMCSVLQHKMEELKEGLRQRDELIEKHGLVIIPDGTPNGDVS---HEPVAGAITVV 253
Query: 225 TKEELNALKSTGDGTLG-RASEVE-VKNEIVANVGKREILHNTEKEQ--HTEDTVKDCVD 280
++E L+S G+G L R ++ K E+++ + K ++ E+++ + TV D
Sbjct: 254 SQEAAQVLESAGEGPLDVRLRKLAGEKEELLSQIRKLKLQLEEERQKCSRNDGTVGDLAG 313
Query: 281 IEVFPAGENTEDQK-SSEDTAPFLGTLAGA-----TYEEQV---QSQILESSSLPENTVQ 331
++ + E Q+ ++ + + L+ A T E+ + + Q+L + EN +
Sbjct: 314 LQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDITTLEQSISRLEGQVLRYKTAAENAEK 373
Query: 332 VE 333
VE
Sbjct: 374 VE 375
>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
isoform 1 [Homo sapiens]
Length = 721
Score = 150 bits (379), Expect = 4e-36
Identities = 84/184 (45%), Positives = 118/184 (64%), Gaps = 28/184 (15%)
Query: 35 AEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSIS 94
+E +I + +L ++ +++ +++T SRN SA+ L G SSRRGSGDTS
Sbjct: 279 SEVDDISIPDLSSLDEKSDKQYAENYTRPSSRN----SASATTPLSGNSSRRGSGDTSSL 334
Query: 95 IDTEASI------------------------REIKDSLAEVEEKYKKAMVSNAQLDNEKT 130
ID + S+ +E+K+SL+EVEEKYKKAMVSNAQLDNEK
Sbjct: 335 IDPDTSLSELRDIYDLKDQIQDVEGRYMQGLKELKESLSEVEEKYKKAMVSNAQLDNEKN 394
Query: 131 NFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREE 190
N +YQVDTLKD++ E EEQ+AE R+ EEK+KE ER+KH S+LQ + E+KE L+QR+E
Sbjct: 395 NLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQRDE 454
Query: 191 MLEK 194
++E+
Sbjct: 455 LIEE 458
Score = 56.6 bits (135), Expect = 8e-08
Identities = 39/94 (41%), Positives = 51/94 (54%), Gaps = 17/94 (18%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE----------------V 52
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE +
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKEYSLHSFDRKWGQIQKWL 76
Query: 53 EERPEKDFTEKGSRNMPGLSAATLASLGGTSSRR 86
E+ ++ + S + P L S+ S R
Sbjct: 77 EDSERARYSHRSSHHRPYLGVEDALSIRSVGSHR 110
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 78.6 bits (192), Expect = 2e-14
Identities = 142/692 (20%), Positives = 268/692 (38%), Gaps = 110/692 (15%)
Query: 96 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 155
DTEA+IR ++ + E A + +LD + + +V L+ EE++A+
Sbjct: 198 DTEAAIRALRKDIEE-------ASLVKVELDKKVQSLQDEVAFLRS---NHEEEVADLLA 247
Query: 156 QYEEKNKEFEREKHAHSILQFQFAEVKEALK--------QREEMLEKHGIILNSEIATNG 207
Q + + ER+ + + + E++ L+ Q EE + L N
Sbjct: 248 QIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNK 307
Query: 208 ETSDTLNN--VGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKN--EIVANVGKREILH 263
E + Y+ + EL +++ T + + S++E ++ ++ + + L
Sbjct: 308 EAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLE 367
Query: 264 NT------EKEQHTED-----TVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATY- 311
N E +H + VK +DIE+ + E +++ T F G++ G Y
Sbjct: 368 NELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFST--FAGSITGPLYT 425
Query: 312 -------EEQVQSQILESSSLP-----------ENTVQVESNEVMGAPDDRTRTPLEPSN 353
++Q +E+ L E V+ E +E+ A T L S
Sbjct: 426 HRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEE-LAVSM 484
Query: 354 CWSDLDGGNHTENVGEAAVTQVEEQAGTV-ASCPLGHSDDTVYHDDKCMVEVPQELETST 412
+ E EA +V + V A+ P ++ +++ E +E E +
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544
Query: 413 GHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPI-------------- 458
E+ + +E + KE E G E EGEE ++EK +
Sbjct: 545 SDQAEEGGSEKEGSSEKE--EGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV 602
Query: 459 -----------KTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEK--SDQQGEA 505
K+ VP SP +G P V+ + + K P EEK S
Sbjct: 603 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVPKSP 660
Query: 506 LDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVE 565
++ K +K +K KSPVP +++ K + + E +EE++VK ++ VE
Sbjct: 661 VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKE-EEEKEVKEAPKEEKVE 719
Query: 566 AQNEVTENPKQKIAAES-------SENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADG 618
+ E ++ +K AES +E V ++ K+ L+ + +EG +Q E+ A G
Sbjct: 720 KKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGG 779
Query: 619 DTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE-- 676
+ G ++ +G K++ ++G + E + E ++ + E E
Sbjct: 780 ----------EGGSEEEGSDKGAKGSRKEDIAVNGEVEGK-EEVEQETKEKGSGREEEKG 828
Query: 677 --SPSQDISDACEAESTERCEMSEHPSQTVRK 706
+ D+S A E + ++ E ++TV K
Sbjct: 829 VVTNGLDLSPADEKKGGDKSEEKVVVTKTVEK 860
Score = 39.3 bits (90), Expect = 0.014
Identities = 58/250 (23%), Positives = 104/250 (41%), Gaps = 28/250 (11%)
Query: 509 SQKKTKNKKKKNKKKKSPVPVETLKD---VKKELTYQNTDLSEIKEEEQVK-STDRKSAV 564
S K K K + K K VE + + V+ E + L+ I EE V ++K A
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 492
Query: 565 EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFE 624
E + E E ++++AA+ S P++K ++EG+ + +E + D
Sbjct: 493 EEKEEEPEAEEEEVAAKKSPVK--ATAPEVK-----EEEGEKEEEEGQEEEEEEDEGAKS 545
Query: 625 DDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISD 684
D + + G E +EG + +G T+ AE + E+A+ + E S++++
Sbjct: 546 DQAEEGGSEKEGSSEKEEGEQE-----EGETE---AEAEGEEAEAKEEKKVEEKSEEVAT 597
Query: 685 ACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFN-PESREDTRGGN--- 740
E + + E E V K+ ++ +P E G P+S + +G +
Sbjct: 598 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 657
Query: 741 -----EKGKS 745
EKGKS
Sbjct: 658 KSPVEEKGKS 667
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 70.1 bits (170), Expect = 7e-12
Identities = 170/806 (21%), Positives = 301/806 (37%), Gaps = 131/806 (16%)
Query: 5 AAAQSREIDCLS--PEAQKLAEARLAAKRAARAEAREI---------RMKELERQQKEVE 53
AA+ + +D LS PE +A +A R+ + + + + ++++LE + +E
Sbjct: 70 AASSTDSLDTLSNGPEGCMVA---VATSRSEKEQLQALNDRFAGYIDKVRQLEAHNRSLE 126
Query: 54 ERPEKDFTEKGSRNMPG-LSAATLASLGGTSSRRGSGDTSISIDTE------ASIREIKD 106
++ R+ G L + + G R G+ + ++ E A +R+ D
Sbjct: 127 GEAAALRQQQAGRSAMGELYEREVREMRGAVLRLGAARGQLRLEQEHLLEDIAHVRQRLD 186
Query: 107 SLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFER 166
A E+ + A + A+ E +VD L+ L+E+ RR ++E+ E
Sbjct: 187 DEARQREEAEAAARALARFAQEAE--AARVD-LQKKAQALQEECGYLRRHHQEEVGELLG 243
Query: 167 EKHAHSILQFQF---------AEVKEALKQREEMLEKHGI--ILNSE------------- 202
+ Q Q +V AL++ LE H + L SE
Sbjct: 244 QIQGSGAAQAQMQAETRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSEA 303
Query: 203 --IATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKRE 260
+ T+ S Y+ + EL ALKST D + SE+E +++ +
Sbjct: 304 AKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEA 363
Query: 261 I------LHNTEKEQHTED-------TVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLA 307
I L NT+ E + VK +DIE+ + E ++ P +L
Sbjct: 364 IQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLP 423
Query: 308 -GATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTEN 366
G V + I S V+ E + + T + TE
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQV--------------TEE 469
Query: 367 VGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAA 426
V E + +E+ G G ++ ++ P E E ++ K +EA
Sbjct: 470 VTEEEEKEAKEEEGKEEE---GGEEEEAEGGEEETKSPPAE-EAASPEKEAKSPVKEEAK 525
Query: 427 EPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQN 486
P E + E + E + E + + P K E P +EA P+ V
Sbjct: 526 SPAEAKSPEKEEAKSPAEVKSPE---KAKSPAKEEAKSPPEAKSPEKEEAKSPAEV---- 578
Query: 487 EPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDL 546
K P++ KS + EA ++ K+ K K K+++ P E VK+E
Sbjct: 579 -----KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA----KSP 629
Query: 547 SEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDD 606
+E+K E+ KS ++ EA++ +K A+S E P +K + K ++
Sbjct: 630 AEVKSPEKAKSPTKE---EAKSPEKAKSPEKEEAKSPEKAKSP----VKAEAKSPEK--- 679
Query: 607 VQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSED 666
A V A+ + + V+ A E + K+ AK SP + KS
Sbjct: 680 ---AKSPVKAEAKSPEKAKSPVKE---EAKSPEKAKSPVKEEAK-------SPEKAKSPV 726
Query: 667 ADRCTLPEH-ESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPG-RE 724
+ PE +SP ++ EA+S E+ + E K+ ++ + ++ +P +
Sbjct: 727 KEEAKTPEKAKSPVKE-----EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781
Query: 725 PGHFNPESREDTRGGNEKGKS--KED 748
P +E+ + EK KS KED
Sbjct: 782 PEKAKSPVKEEVK-SPEKAKSPLKED 806
Score = 49.7 bits (117), Expect = 1e-05
Identities = 106/600 (17%), Positives = 225/600 (37%), Gaps = 52/600 (8%)
Query: 88 SGDTSISIDTEASIREIKDSLAE---VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLL 144
S T I + +E I+ ++ S E VEE+ ++ V+ + E+ + ++
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE 490
Query: 145 ELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA 204
E E + E + + EK A S ++ + EA +E + + + E A
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKA 550
Query: 205 TNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEV----EVKN-EIVANVGKR 259
+ + + + P K + +KS E E K+ E + K
Sbjct: 551 KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610
Query: 260 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 319
E E + ++ K +++ ++ +++ A E+ +S +
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPV 670
Query: 320 LESSSLPENT---VQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVE 376
+ PE V+ E+ A P S + E A + V+
Sbjct: 671 KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV---KEEAKSPEKAKSPVK 727
Query: 377 EQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV---PA 433
E+A T ++ + E + L+ + + K +EA P + A
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA--KTPAKEEARSPADKFPEKA 785
Query: 434 HSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKE 493
S + E+ + D K + E+P +E P + + + + +KE
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK--------EEVKSPVKEEEKPQEVKVKE 837
Query: 494 PDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVP-VETLKDVKKELTYQN---TDLSEI 549
P ++ +++ A +++K +KK++ KK++P P VE K+ E ++ E
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Query: 550 KEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQT 609
+++++V + ++++ + + + PK+K E P++ K K K ++ +
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKE----PDDAKAKEPSKPAEK----KE 949
Query: 610 AAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADR 669
AA E + DT + + + E AK++ D P++PK+E A++
Sbjct: 950 AAPE----------KKDTKEEKAKKPEEKPKTEAKAKED---DKTLSKEPSKPKAEKAEK 996
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 68.2 bits (165), Expect = 3e-11
Identities = 106/490 (21%), Positives = 191/490 (38%), Gaps = 77/490 (15%)
Query: 275 VKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATY--------EEQVQSQILESSSLP 326
VK +DIE+ + E +++ T F G++ G Y ++Q +E+ L
Sbjct: 14 VKMALDIEIAAYRKLLEGEETRFST--FAGSITGPLYTHRPPITISSKIQKPKVEAPKLK 71
Query: 327 -----------ENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQV 375
E V+ E +E+ A T L S + E EA +V
Sbjct: 72 VQHKFVEEIIEETKVEDEKSEMEEALTAITEE-LAVSMKEEKKEAAEEKEEEPEAEEEEV 130
Query: 376 EEQAGTV-ASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAH 434
+ V A+ P ++ +++ E +E E + E+ + +E + KE
Sbjct: 131 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKE--EG 188
Query: 435 STEVGRDHNEEEGEETGLRDEKPI-------------------------KTEVPGSPAGT 469
E G E EGEE ++EK + K+ VP SP
Sbjct: 189 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 248
Query: 470 EGNCQEATGPSTVDTQNEPLDMKEPDEEK--SDQQGEALDSSQKKTKNKKKKNKKKKSPV 527
+G P V+ + + K P EEK S ++ K +K +K KSPV
Sbjct: 249 KGKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 306
Query: 528 PVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAES----- 582
P +++ K + + E +EE++VK ++ VE + E ++ +K AES
Sbjct: 307 PKSPVEEAKSKAEVGKGEQKE-EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 365
Query: 583 --SENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEEL 640
+E V ++ K+ L+ + +EG +Q E+ A G + G ++
Sbjct: 366 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGG----------EGGSEEEGSDKG 415
Query: 641 DEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE----SPSQDISDACEAESTERCEM 696
+G K++ ++G + E + E ++ + E E + D+S A E + ++ E
Sbjct: 416 AKGSRKEDIAVNGEVEGK-EEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEE 474
Query: 697 SEHPSQTVRK 706
++TV K
Sbjct: 475 KVVVTKTVEK 484
Score = 39.3 bits (90), Expect = 0.014
Identities = 58/250 (23%), Positives = 104/250 (41%), Gaps = 28/250 (11%)
Query: 509 SQKKTKNKKKKNKKKKSPVPVETLKD---VKKELTYQNTDLSEIKEEEQVK-STDRKSAV 564
S K K K + K K VE + + V+ E + L+ I EE V ++K A
Sbjct: 57 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 116
Query: 565 EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFE 624
E + E E ++++AA+ S P++K ++EG+ + +E + D
Sbjct: 117 EEKEEEPEAEEEEVAAKKSPVK--ATAPEVK-----EEEGEKEEEEGQEEEEEEDEGAKS 169
Query: 625 DDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISD 684
D + + G E +EG + +G T+ AE + E+A+ + E S++++
Sbjct: 170 DQAEEGGSEKEGSSEKEEGEQE-----EGETE---AEAEGEEAEAKEEKKVEEKSEEVAT 221
Query: 685 ACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFN-PESREDTRGGN--- 740
E + + E E V K+ ++ +P E G P+S + +G +
Sbjct: 222 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 281
Query: 741 -----EKGKS 745
EKGKS
Sbjct: 282 KSPVEEKGKS 291
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 59.7 bits (143), Expect = 1e-08
Identities = 75/365 (20%), Positives = 135/365 (36%), Gaps = 30/365 (8%)
Query: 403 EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 462
E ++ E GH E+ NQE E E E EEE E+ G E+ EV
Sbjct: 708 EEQEQKEREQGHQKER---NQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEV 764
Query: 463 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 522
G EG ++ + E D E +EE+++ +GE + + + ++ K
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG 824
Query: 523 KKSPVPVETLKDV-------------------KKELTYQNTDLSEIKEEEQVKSTDRKSA 563
++ E + K E + + E EE + + + +
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 564 VEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDF 623
E + E +++ E E + + +GK ++EG++ + EE +G+ D
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 624 EDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDIS 683
E + + G G EE EG ++ +G + E + E+ + E E ++
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEE----EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000
Query: 684 DACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKG 743
+ E E E E V ++ E + G E G E RE G E
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG----EEREKEGEGEENR 1056
Query: 744 KSKED 748
+++E+
Sbjct: 1057 RNREE 1061
Score = 47.8 bits (112), Expect = 4e-05
Identities = 72/375 (19%), Positives = 138/375 (36%), Gaps = 50/375 (13%)
Query: 400 CMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEE----GEETGLRDE 455
C V Q + + + + F+++E P+E G E+E E +
Sbjct: 559 CKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGG 618
Query: 456 KPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKN 515
+ KTE+ + E S + ++ P E + D E S + ++
Sbjct: 619 RKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGP-------EGRGDGTCEEGSSGAEHWQD 671
Query: 516 KKK-KNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENP 574
+++ K +K K +E + +KEL + EE++ K ++ E E+ E
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731
Query: 575 KQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLA----------------DG 618
+++ E D E + + +GK + EG++V+ E+ +G
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG 791
Query: 619 DTLDFEDDTVQSSG--PRAGGE----ELDEGVA-KDNAKIDGATQSSPAEPKSEDADRCT 671
D + E++ + G GGE E++EG ++ + +G + E + E+ +
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG-- 849
Query: 672 LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 731
E E + + E E E E E E ++ G E G E
Sbjct: 850 -EEEEGEGKGEEEGEEGEGEEEGEEGEGEG------------EEEEGEGEGEEEGEGEGE 896
Query: 732 SREDTRGGNEKGKSK 746
E G E+G+ +
Sbjct: 897 EEEGEGEGEEEGEGE 911
Score = 42.7 bits (99), Expect = 0.001
Identities = 119/569 (20%), Positives = 198/569 (34%), Gaps = 62/569 (10%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAK--RAARAEAREIRMKE----LERQQKEVEE 54
MT PA I+ S E ++ E + A+ + E +E+ E + +KE E
Sbjct: 569 MTQPATT----IEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTE 624
Query: 55 RPEKDFTEKGSRNMPGLSAATLASLG-GTSSRRGSGDTSISIDTEASIREIKDSLAEVEE 113
D T+K +S S+G G GD + + + +D E E
Sbjct: 625 ILSDDLTDKAE-----VSEGKAKSVGEAEDGPEGRGDGTCE-EGSSGAEHWQDEEREKGE 678
Query: 114 KYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFER---EKHA 170
K K + EK + + + K E +EQ + +E+N+E E E+H
Sbjct: 679 KDKGRGEMERPGEGEKE--LAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG 736
Query: 171 HSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQ---GPTKMTKE 227
E +E ++ EE E G GE + G + +E
Sbjct: 737 EG-------EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789
Query: 228 ELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAG 287
E + + + T GR E E E+ + E+E+ E ++ E G
Sbjct: 790 EGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG 849
Query: 288 ENTEDQ-KSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTR 346
E E + K E+ G G E + + + E E + E E G ++
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE--- 906
Query: 347 TPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQ 406
E + +G E GE + EE+ G G +D ++ E
Sbjct: 907 ---EGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE------GEGEDGEGEGEEEEGEWEG 957
Query: 407 ELETSTGHSLEK-EFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEK--------- 456
E E G E+ E +E E E + EEEGEE G +E+
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Query: 457 --PIKTEVPGSPAGTEGNCQEATGPSTV-----DTQNEPLDMKEPDEEKSDQQGEALDSS 509
++ EV G EG +E + + + +E +EE+ Q + +
Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEEN 1077
Query: 510 QKKTKNKKKKNKKKKSPVPVETLKDVKKE 538
+++ + KK K K V K +K+
Sbjct: 1078 ERQDGEEYKKVSKIKGSVKYGKHKTYQKK 1106
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/317 (22%), Positives = 131/317 (41%), Gaps = 37/317 (11%)
Query: 443 NEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQ 502
+E +E+ L ++ ++ E P E STV++ E D+ S
Sbjct: 451 SERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMS--- 507
Query: 503 GEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTY-QNTDLSEIKEEEQVKSTDRK 561
L+S++K K + +KK+ +T+ ++ ++ +N D E +E ++K
Sbjct: 508 ---LNSNEKSLKLSPVQKQKKQ-----QTIGELTQDTALTENDDSDEYEEMSEMKEGKAC 559
Query: 562 SAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTL 621
+Q P I A S E V+ PE + +G D +G+ ++ +EV A+
Sbjct: 560 KQHVSQGIFMTQPATTIEAFSDEEVEIPE----EKEGAEDSKGNGIE--EQEVEAN---- 609
Query: 622 DFEDDTVQSSGPRAGGEELDEGVAKDNAKI-DGATQS-SPAEPKSEDADRCTLPEHESPS 679
++ V+ G R E+ D A++ +G +S AE E T E S +
Sbjct: 610 ---EENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGA 666
Query: 680 QDISDACEAESTE----RCEMSEHPSQTVRKALDS---NSLENDDLSAPGREPGHFNPES 732
+ D E E E R EM E P + ++ + + ++ RE GH +
Sbjct: 667 EHWQDE-EREKGEKDKGRGEM-ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERN 724
Query: 733 REDTRGGNEK-GKSKED 748
+E GG E+ G+ +E+
Sbjct: 725 QEMEEGGEEEHGEGEEE 741
Score = 35.4 bits (80), Expect = 0.20
Identities = 108/511 (21%), Positives = 171/511 (33%), Gaps = 66/511 (12%)
Query: 46 ERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK 105
E Q E E+ EKD +G PG LA R G E K
Sbjct: 667 EHWQDEEREKGEKD-KGRGEMERPGEGEKELAEKEEWKKRDGEEQEQ----KEREQGHQK 721
Query: 106 DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE 165
+ E+EE ++ + + ++ E EE+ E + + E + E E
Sbjct: 722 ERNQEMEEGGEEEHGEGEEEEGDRE--------------EEEEKEGEGKEEGEGEEVEGE 767
Query: 166 REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMT 225
REK + + A +E K EE + G E GE + V G +
Sbjct: 768 REKEEGERKKEERAGKEE--KGEEEGDQGEGE--EEETEGRGEEKEEGGEVE-GGEVEEG 822
Query: 226 KEELNALKSTGDGTL--GRASEVEVKNEIVANVGK-REILHNTEKEQHTEDTVKDCVDIE 282
K E + G+G G E E + E GK E E E+ E+ + + E
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Query: 283 VFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPD 342
GE + + E+ G G E+ + + E + E E G +
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942
Query: 343 DRTRTPLEPSNCWS------DLDGGNHTENVGEAAVTQVEEQAGTVASCPL--------- 387
D E W + +G E GE + EE+ G
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Query: 388 --GHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEE 445
G + +++ EV E+E G +E +E E +E E R+ EE
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEE 1062
Query: 446 EGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEA 505
E E EG QE TG + Q+ K + S + G+
Sbjct: 1063 EEE---------------------EGKYQE-TGEEENERQDGEEYKKVSKIKGSVKYGKH 1100
Query: 506 LDSSQKKTKNKKKKNKKKKSPVPVETLKDVK 536
+K N + K+++S +PV++ + +K
Sbjct: 1101 KTYQKKSVTNTQGNGKEQRSKMPVQSKRLLK 1131
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 58.2 bits (139), Expect = 3e-08
Identities = 79/378 (20%), Positives = 149/378 (39%), Gaps = 56/378 (14%)
Query: 390 SDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEV----------G 439
SDDT+ ++ + + +T S +E N++ + K ST+ G
Sbjct: 140 SDDTIQASEESAPQGQDSAQDTTSES--RELDNEDRVDSKPEGGDSTQESESEEHWVGGG 197
Query: 440 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 499
D G+ + L DE ++++ P S GN ++ MK + ++
Sbjct: 198 SDGESSHGDGSELDDEG-MQSDDPESIRSERGN-----------SRMNSAGMKSKESGEN 245
Query: 500 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 559
+Q DS + + +KS + E D + EL NT + E+K + S
Sbjct: 246 SEQANTQDSGGSQLLEHPSRKIFRKSRISEE---DDRSELDDNNT-MEEVKSDSTENSNS 301
Query: 560 RKSAV-----EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 614
R + + +++ + E+ K+ ++ E S+NVD P + + QE + EEV
Sbjct: 302 RDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS--ESQEEV 359
Query: 615 LAD--GD----TLDFEDDTVQSSGPR---------AGGEELDEGVAKDNAKIDGATQSSP 659
+++ GD T + +D S + E +E ++++ ++ SP
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 419
Query: 660 AEPKSEDADRCT-LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDL 718
P+ E++ L H S ++ S+ +E E + R DSNS E+
Sbjct: 420 ESPEDENSSSQEGLQSHSSSAESQSEESHSE-----EDDSDSQDSSRSKEDSNSTESKSS 474
Query: 719 SAPGREPGHFNPESREDT 736
S + + ESR+ T
Sbjct: 475 SEEDGQLKNIEIESRKLT 492
Score = 47.0 bits (110), Expect = 7e-05
Identities = 72/422 (17%), Positives = 163/422 (38%), Gaps = 42/422 (9%)
Query: 288 ENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRT 347
++ ++ S +DT + G ++ + L S ++T+Q D T
Sbjct: 102 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 161
Query: 348 PLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA-----GTVASCPLGHSDDTVYHDDKCMV 402
E +LD + ++ E + E ++ G + H D + D+
Sbjct: 162 TSESR----ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQS 217
Query: 403 EVPQELETSTGHSL--------------EKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 448
+ P+ + + G+S ++ Q++ + + S ++ R E +
Sbjct: 218 DDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEED 277
Query: 449 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 508
+ D+ EV TE + TG S ++ ++ E S ++ + +D
Sbjct: 278 DRSELDDNNTMEEVKSD--STENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 335
Query: 509 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD--LSEIKEEEQVKSTDRKSAVEA 566
++ + + ++ S E+ ++V E N D S ++++E S++ S+
Sbjct: 336 PSSESSQEANLSSQENSS---ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTL 392
Query: 567 QNEVTENPKQKIAAESSENV----DCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLD 622
+ +E+ +++ +ESSE++ + PE+P+ + QEG +Q+ + + +
Sbjct: 393 SHSKSESREEQADSESSESLNFSEESPESPED--ENSSSQEG--LQSHSSSAESQSEESH 448
Query: 623 FEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDI 682
E+D S E+ + +K +++ DG ++ E + D H P D
Sbjct: 449 SEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD----AYHNKPIGDQ 504
Query: 683 SD 684
D
Sbjct: 505 DD 506
Score = 31.6 bits (70), Expect = 2.8
Identities = 43/200 (21%), Positives = 74/200 (37%), Gaps = 26/200 (13%)
Query: 562 SAVEAQNEVTENPKQKIAAESSENVDCPENPKI-KLDGKL--------DQEGDDVQTAAE 612
S V ++ + E+P + +S E + ++ I +L G D + DD + +
Sbjct: 54 SKVSSEEQANEDPSD--STQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGD 111
Query: 613 EVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTL 672
+ D D+ D + R G +E + D S + P+ +D+ + T
Sbjct: 112 DTFGDDDSGPGPKDRQEGGNSRLGSDEDSD---------DTIQASEESAPQGQDSAQDTT 162
Query: 673 PE-HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 731
E E ++D D+ + E + + SE V D S D +PE
Sbjct: 163 SESRELDNEDRVDS-KPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPE 221
Query: 732 SREDTRGGNEKG----KSKE 747
S RG + KSKE
Sbjct: 222 SIRSERGNSRMNSAGMKSKE 241
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 58.2 bits (139), Expect = 3e-08
Identities = 79/378 (20%), Positives = 149/378 (39%), Gaps = 56/378 (14%)
Query: 390 SDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEV----------G 439
SDDT+ ++ + + +T S +E N++ + K ST+ G
Sbjct: 124 SDDTIQASEESAPQGQDSAQDTTSES--RELDNEDRVDSKPEGGDSTQESESEEHWVGGG 181
Query: 440 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 499
D G+ + L DE ++++ P S GN ++ MK + ++
Sbjct: 182 SDGESSHGDGSELDDEG-MQSDDPESIRSERGN-----------SRMNSAGMKSKESGEN 229
Query: 500 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 559
+Q DS + + +KS + E D + EL NT + E+K + S
Sbjct: 230 SEQANTQDSGGSQLLEHPSRKIFRKSRISEE---DDRSELDDNNT-MEEVKSDSTENSNS 285
Query: 560 RKSAV-----EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 614
R + + +++ + E+ K+ ++ E S+NVD P + + QE + EEV
Sbjct: 286 RDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS--ESQEEV 343
Query: 615 LAD--GD----TLDFEDDTVQSSGPR---------AGGEELDEGVAKDNAKIDGATQSSP 659
+++ GD T + +D S + E +E ++++ ++ SP
Sbjct: 344 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 403
Query: 660 AEPKSEDADRCT-LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDL 718
P+ E++ L H S ++ S+ +E E + R DSNS E+
Sbjct: 404 ESPEDENSSSQEGLQSHSSSAESQSEESHSE-----EDDSDSQDSSRSKEDSNSTESKSS 458
Query: 719 SAPGREPGHFNPESREDT 736
S + + ESR+ T
Sbjct: 459 SEEDGQLKNIEIESRKLT 476
Score = 47.0 bits (110), Expect = 7e-05
Identities = 72/422 (17%), Positives = 163/422 (38%), Gaps = 42/422 (9%)
Query: 288 ENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRT 347
++ ++ S +DT + G ++ + L S ++T+Q D T
Sbjct: 86 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 145
Query: 348 PLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA-----GTVASCPLGHSDDTVYHDDKCMV 402
E +LD + ++ E + E ++ G + H D + D+
Sbjct: 146 TSESR----ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQS 201
Query: 403 EVPQELETSTGHSL--------------EKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 448
+ P+ + + G+S ++ Q++ + + S ++ R E +
Sbjct: 202 DDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEED 261
Query: 449 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 508
+ D+ EV TE + TG S ++ ++ E S ++ + +D
Sbjct: 262 DRSELDDNNTMEEVKSD--STENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 319
Query: 509 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD--LSEIKEEEQVKSTDRKSAVEA 566
++ + + ++ S E+ ++V E N D S ++++E S++ S+
Sbjct: 320 PSSESSQEANLSSQENSS---ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTL 376
Query: 567 QNEVTENPKQKIAAESSENV----DCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLD 622
+ +E+ +++ +ESSE++ + PE+P+ + QEG +Q+ + + +
Sbjct: 377 SHSKSESREEQADSESSESLNFSEESPESPED--ENSSSQEG--LQSHSSSAESQSEESH 432
Query: 623 FEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDI 682
E+D S E+ + +K +++ DG ++ E + D H P D
Sbjct: 433 SEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD----AYHNKPIGDQ 488
Query: 683 SD 684
D
Sbjct: 489 DD 490
Score = 30.4 bits (67), Expect = 6.3
Identities = 34/152 (22%), Positives = 55/152 (36%), Gaps = 15/152 (9%)
Query: 601 DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPA 660
D + DD + ++ D D+ D + R G +E + D S +
Sbjct: 84 DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSD---------DTIQASEES 134
Query: 661 EPKSEDADRCTLPE-HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLS 719
P+ +D+ + T E E ++D D+ + E + + SE V D S D
Sbjct: 135 APQGQDSAQDTTSESRELDNEDRVDS-KPEGGDSTQESESEEHWVGGGSDGESSHGDGSE 193
Query: 720 APGREPGHFNPESREDTRGGNEKG----KSKE 747
+PES RG + KSKE
Sbjct: 194 LDDEGMQSDDPESIRSERGNSRMNSAGMKSKE 225
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 57.0 bits (136), Expect = 6e-08
Identities = 97/430 (22%), Positives = 166/430 (38%), Gaps = 48/430 (11%)
Query: 308 GATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV 367
G+ +E+ +Q + ++ Q + E + AP+ E + G+ E
Sbjct: 1807 GSGHEDNLQGEAAAGGD--QDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAE 1864
Query: 368 GEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAE 427
GEA + +A S+D + EV E E + EKE E
Sbjct: 1865 GEAQPESEDVEAPEAEGEAQPESEDV--ETPEAEWEVQPESEGAEAPEAEKE----AQPE 1918
Query: 428 PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNE 487
+ V A TE G D E EG E +E + E P QEA ++E
Sbjct: 1919 TESVEALETE-GEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAE--EEAQPESE 1975
Query: 488 PLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDL- 546
++ E + E + +GEA S+ ++P +++ ++E ++ +
Sbjct: 1976 DVEALEVEVETQEAEGEAQPESEDV-----------EAPEAEGEMQEAEEEAQPESDGVE 2024
Query: 547 ----SEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQ 602
SE +E ++V+ +K+ +AQ E A E+ E E + +G+
Sbjct: 2025 AQPKSEGEEAQEVEGETQKTEGDAQPESDGVE----APEAEEEAQEAEGEVQEAEGEAHP 2080
Query: 603 EGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEP 662
E +DV A+E A+G+ + ++ P A EG A+ I+ A+P
Sbjct: 2081 ESEDVD--AQE--AEGEA---QPESEGVEAPEA------EGEAQKAEGIEAPETEGEAQP 2127
Query: 663 KSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPG 722
+SE + PE E +Q S+ EA+ E E ++A + E + + AP
Sbjct: 2128 ESEGIE---APEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184
Query: 723 REPGHFNPES 732
E G PES
Sbjct: 2185 AE-GEAQPES 2193
Score = 51.2 bits (121), Expect = 3e-06
Identities = 107/546 (19%), Positives = 207/546 (37%), Gaps = 76/546 (13%)
Query: 165 EREKHAHSILQFQFAEVKEALKQREEMLEK---------HGIILNSEIATNGET------ 209
ERE H+ +E+ EA ++ E + E+ H L E A G+
Sbjct: 1771 EREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSD 1830
Query: 210 -SDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 268
++ + +G + E + A ++ GD ++ A + E +
Sbjct: 1831 GAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA------Q 1884
Query: 269 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLA-------------GATYEEQV 315
+ED + EV P E E ++ ++ P ++ GA +E
Sbjct: 1885 PESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE 1944
Query: 316 QS-QILESSSLPENTVQVESNEVM--GAPDDRTRTPLEPSNCWSDLDGGNHTENVG-EAA 371
++ Q E + PE+ V +ES E P+ LE + +G E+ EA
Sbjct: 1945 EAAQEAEGQTQPESEV-IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAP 2003
Query: 372 VTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV 431
+ E Q + P D V K E QE+E T + + A+P+
Sbjct: 2004 EAEGEMQEAEEEAQP---ESDGVEAQPKSEGEEAQEVEGETQKT-------EGDAQPESD 2053
Query: 432 PAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDM 491
+ E + E EGE + E P + + QEA G + Q E +
Sbjct: 2054 GVEAPEAEEEAQEAEGEVQ--------EAEGEAHPESEDVDAQEAEG----EAQPESEGV 2101
Query: 492 KEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKE 551
+ P+ E Q+ E +++ + + + + +++ ++P + + + Q+ + E
Sbjct: 2102 EAPEAEGEAQKAEGIEAPETEGE-AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPE 2160
Query: 552 EEQVKSTDRKSAVEAQNEVTENPKQKIAAE-SSENVDCPENPKIKLDGKLDQEGDDVQTA 610
E +++ + + + + E E P+ + A+ SE ++ PE + + + + EG + A
Sbjct: 2161 SEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPE---AEGEAQPELEGVEAPEA 2217
Query: 611 AEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRC 670
EE + + ++ P A GE E + + G+ Q S + +SE+A
Sbjct: 2218 EEEAQPEPEGVET---------PEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASES 2268
Query: 671 TLPEHE 676
+ P E
Sbjct: 2269 SSPVPE 2274
Score = 40.4 bits (93), Expect = 0.006
Identities = 50/219 (22%), Positives = 90/219 (41%), Gaps = 22/219 (10%)
Query: 542 QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLD 601
+NT E++ EE + T+ + E ++ E ++ E E V E + + +G+ +
Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQE--EGVQLEETKETEGEGQQE 1351
Query: 602 QEG---DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAG--GEELDEGVAKDNAKIDGA-- 654
+E + +T E + +G L+ + GP G GE L+EG+ ++ +G+
Sbjct: 1352 EEAQLEEIEETGGEGLQEEGVQLEEVKE-----GPEGGLQGEALEEGLKEEGLPEEGSVH 1406
Query: 655 ----TQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTER-CEMSEHPSQTVRKALD 709
+++S + K D E + ++ C AE TE E H S+T A +
Sbjct: 1407 GQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASE 1466
Query: 710 SNS---LENDDLSAPGREPGHFNPESREDTRGGNEKGKS 745
S LE PG + T+G E+ S
Sbjct: 1467 RQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSS 1505
Score = 36.6 bits (83), Expect = 0.088
Identities = 132/639 (20%), Positives = 221/639 (34%), Gaps = 91/639 (14%)
Query: 148 EQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNG 207
EQLAE+ Q EE E +E LQ + +++E + EE L++ G+ L T G
Sbjct: 1290 EQLAENTVQ-EEVQLEETKEGTEGEGLQEEAVQLEET--KTEEGLQEEGVQLEETKETEG 1346
Query: 208 ETSDT----LNNVGYQGPTKMTKE--ELNALKSTGDGTL-GRASEVEVKNEIVANVGKRE 260
E L + G + +E +L +K +G L G A E +K E + G
Sbjct: 1347 EGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGS-- 1404
Query: 261 ILHNTE---------KEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAP--FLGTLAGA 309
+H E K +D V++ + E + + E T P L +
Sbjct: 1405 -VHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPS 1463
Query: 310 TYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV-- 367
E Q SQ+ P + P C + LD +V
Sbjct: 1464 ASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVLL 1523
Query: 368 --GEAAVTQVEEQAGTVASCPLGHSDDTVYHD--DKCMVEVPQELETSTGHSLEK---EF 420
E A A G D+ + + +V Q L+ ST L+K
Sbjct: 1524 KKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQGRA 1583
Query: 421 TNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS 480
P+E A + E+ + GLR+ G GP
Sbjct: 1584 GRMVLEPPRE--ALTGELLLQTQQRRHRLRGLRNLSAFSERTLG------------LGPL 1629
Query: 481 TVDTQNEP-LDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKEL 539
+ ++EP L + + +GE + + KK SP+ + +
Sbjct: 1630 SFTLEDEPALSTALGSQLGEEAEGEEFCPCEACVR-------KKVSPMSPKATMGATRGP 1682
Query: 540 TYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCP---ENPKIKL 596
+ DL +I + ++ + TD ++A A + +P + +E P + P +
Sbjct: 1683 IKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGV-- 1740
Query: 597 DGKLDQEGDDVQTAAEEVL---ADGDTLDFEDDTVQSSGPRAGGEEL------DEGVA-- 645
D D EG ++ A+GD + E + + + G EL EG++
Sbjct: 1741 DEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISER 1800
Query: 646 ----------KDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCE 695
+DN + + A +S+ A+ PE E +Q S+ EA E
Sbjct: 1801 GETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAE--- 1857
Query: 696 MSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESRE 734
++A E++D+ AP E G PES +
Sbjct: 1858 ------GDAQEAEGEAQPESEDVEAPEAE-GEAQPESED 1889
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 55.8 bits (133), Expect = 1e-07
Identities = 125/646 (19%), Positives = 261/646 (40%), Gaps = 76/646 (11%)
Query: 7 AQSREIDCLSPEAQKLAE--ARLAAKRAARAEAREIRMKELERQQKEVEERPE-KDFTEK 63
A ++ L+ E L E A+L ++ A EA + + +L+ ++ +V + K E+
Sbjct: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQ 1035
Query: 64 GSRNMPGL--SAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS 121
++ G L + R+ GD ++ + SI +I++ +++EK KK
Sbjct: 1036 QVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA---QESIMDIENEKQQLDEKLKKK--- 1089
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEV 181
+ E +N +++ + + ++L++++ E + + EE +E E E+ + + + Q +++
Sbjct: 1090 ----EFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG 241
L++ E LE+ G +++I N + + + EE TL
Sbjct: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKM------RRDLEEATLQHEATAATLR 1199
Query: 242 RASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTED-QKSSEDTA 300
+ + VA +G++ + N ++ + + K + +E+ N E K+ +
Sbjct: 1200 KKHA-----DSVAELGEQ--IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLE 1252
Query: 301 PFLGTLAGATYE----EQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWS 356
TL E E+ Q +++ + +Q ES E D++ S
Sbjct: 1253 KMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALV-------S 1305
Query: 357 DLDGGNH--TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM---VEVPQELETS 411
L G T+ + E Q+EE+ A L H+ + HD + E QE +
Sbjct: 1306 QLSRGKQAFTQQIEELK-RQLEEEIK--AKNALAHALQSSRHDCDLLREQYEEEQESKAE 1362
Query: 412 TGHSLEKEFTN----------------QEAAEPKEVPAHSTEVGRDHNEEEGEETGL--R 453
+L K T +E E K+ A + +H E + +
Sbjct: 1363 LQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEK 1422
Query: 454 DEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPD-EEKSDQQGEALDSSQKK 512
++ ++ EV E + + +D + D + ++K ++ L++SQK+
Sbjct: 1423 TKQRLQNEVEDLMLDVE---RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE 1479
Query: 513 TKNK-----KKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQ 567
++ K KN ++S +ETLK K L + +DL+E + E K ++ Q
Sbjct: 1480 ARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE-QIAEGGKRIHELEKIKKQ 1538
Query: 568 NEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEE 613
E + Q E+ +++ E +++ +L+Q +V E
Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584
Score = 32.7 bits (73), Expect = 1.3
Identities = 118/618 (19%), Positives = 232/618 (37%), Gaps = 82/618 (13%)
Query: 46 ERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSIS--IDTEASIRE 103
E ++KE+EE+ EK L A G + D I I EA I+E
Sbjct: 873 EAKRKELEEKMVTLLKEKND-----LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKE 927
Query: 104 IKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQ---YEEK 160
+ + + EE NA+L +K + LK + +LE LA+ ++ E K
Sbjct: 928 VTERAEDEEE-------INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
Query: 161 NKEFEREKHAHSILQFQFAEVKEALKQREEML--------EKHGIILNSEIATNGETSDT 212
K E + + K+AL++ + +K + ++I + D
Sbjct: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040
Query: 213 LNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNE---IVANVGKRE-----ILHN 264
++ + +M E K GD L + S ++++NE + + K+E +
Sbjct: 1041 EGSLEQEKKLRMDLERAKR-KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099
Query: 265 TEKEQ----HTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQIL 320
E EQ + +K+ + + E E +++S A + EE + ++
Sbjct: 1100 IEDEQALGIQLQKKIKE-LQARIEELEEEIEAERASRAKAEKQRSDLSRELEE-ISERLE 1157
Query: 321 ESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGG----NHTENVGEAAVTQVE 376
E+ + Q+E N+ A + R LE + + H ++V E Q++
Sbjct: 1158 EAGG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG-EQID 1214
Query: 377 EQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEK----------EFTNQEAA 426
S+ + DD + E + +LEK E ++E
Sbjct: 1215 NLQRVKQKLEKEKSEMKMEIDD---LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEE 1271
Query: 427 EPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQN 486
+ + + + + GR E GE + DEK Q + G Q
Sbjct: 1272 QQRLINDLTAQRGR-LQTESGEFSRQLDEKEALVS------------QLSRGKQAFTQQI 1318
Query: 487 EPLDMKEPDEEKS-DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD 545
E L + +E K+ + AL SS+ +++ ++++ E+ ++++ L+ NT+
Sbjct: 1319 EELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQ-----ESKAELQRALSKANTE 1373
Query: 546 LSEIKEEEQVKSTDRKSAV-EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 604
+++ + + + + R + EA+ ++ + + + N C K K +L E
Sbjct: 1374 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK--QRLQNEV 1431
Query: 605 DDVQTAAEEVLADGDTLD 622
+D+ E A LD
Sbjct: 1432 EDLMLDVERTNAACAALD 1449
Score = 31.6 bits (70), Expect = 2.8
Identities = 38/183 (20%), Positives = 75/183 (40%), Gaps = 18/183 (9%)
Query: 22 LAEARLAAKRAARAEAREIRMKELERQQKEVE---ERPEKDFTEKGSRNMPGLSAATLAS 78
L EAR A ++A +A M E +++++ ER +K+ + L A +
Sbjct: 1751 LQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLA 1810
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD- 137
L G G I EA +RE++ + +++ +A+ + + YQ +
Sbjct: 1811 LKG-------GKKQIQ-KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEE 1862
Query: 138 ------TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEM 191
L+D++ +L+ ++ +RQ EE ++ LQ + E +E E
Sbjct: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQ 1922
Query: 192 LEK 194
+ K
Sbjct: 1923 VNK 1925
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 55.8 bits (133), Expect = 1e-07
Identities = 125/646 (19%), Positives = 261/646 (40%), Gaps = 76/646 (11%)
Query: 7 AQSREIDCLSPEAQKLAE--ARLAAKRAARAEAREIRMKELERQQKEVEERPE-KDFTEK 63
A ++ L+ E L E A+L ++ A EA + + +L+ ++ +V + K E+
Sbjct: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQ 1035
Query: 64 GSRNMPGL--SAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS 121
++ G L + R+ GD ++ + SI +I++ +++EK KK
Sbjct: 1036 QVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA---QESIMDIENEKQQLDEKLKKK--- 1089
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEV 181
+ E +N +++ + + ++L++++ E + + EE +E E E+ + + + Q +++
Sbjct: 1090 ----EFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG 241
L++ E LE+ G +++I N + + + EE TL
Sbjct: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKM------RRDLEEATLQHEATAATLR 1199
Query: 242 RASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTED-QKSSEDTA 300
+ + VA +G++ + N ++ + + K + +E+ N E K+ +
Sbjct: 1200 KKHA-----DSVAELGEQ--IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLE 1252
Query: 301 PFLGTLAGATYE----EQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWS 356
TL E E+ Q +++ + +Q ES E D++ S
Sbjct: 1253 KMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALV-------S 1305
Query: 357 DLDGGNH--TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM---VEVPQELETS 411
L G T+ + E Q+EE+ A L H+ + HD + E QE +
Sbjct: 1306 QLSRGKQAFTQQIEELK-RQLEEEIK--AKNALAHALQSSRHDCDLLREQYEEEQESKAE 1362
Query: 412 TGHSLEKEFTN----------------QEAAEPKEVPAHSTEVGRDHNEEEGEETGL--R 453
+L K T +E E K+ A + +H E + +
Sbjct: 1363 LQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEK 1422
Query: 454 DEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPD-EEKSDQQGEALDSSQKK 512
++ ++ EV E + + +D + D + ++K ++ L++SQK+
Sbjct: 1423 TKQRLQNEVEDLMLDVE---RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE 1479
Query: 513 TKNK-----KKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQ 567
++ K KN ++S +ETLK K L + +DL+E + E K ++ Q
Sbjct: 1480 ARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE-QIAEGGKRIHELEKIKKQ 1538
Query: 568 NEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEE 613
E + Q E+ +++ E +++ +L+Q +V E
Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584
Score = 32.7 bits (73), Expect = 1.3
Identities = 118/618 (19%), Positives = 232/618 (37%), Gaps = 82/618 (13%)
Query: 46 ERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSIS--IDTEASIRE 103
E ++KE+EE+ EK L A G + D I I EA I+E
Sbjct: 873 EAKRKELEEKMVTLLKEKND-----LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKE 927
Query: 104 IKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQ---YEEK 160
+ + + EE NA+L +K + LK + +LE LA+ ++ E K
Sbjct: 928 VTERAEDEEE-------INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
Query: 161 NKEFEREKHAHSILQFQFAEVKEALKQREEML--------EKHGIILNSEIATNGETSDT 212
K E + + K+AL++ + +K + ++I + D
Sbjct: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040
Query: 213 LNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNE---IVANVGKRE-----ILHN 264
++ + +M E K GD L + S ++++NE + + K+E +
Sbjct: 1041 EGSLEQEKKLRMDLERAKR-KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099
Query: 265 TEKEQ----HTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQIL 320
E EQ + +K+ + + E E +++S A + EE + ++
Sbjct: 1100 IEDEQALGIQLQKKIKE-LQARIEELEEEIEAERASRAKAEKQRSDLSRELEE-ISERLE 1157
Query: 321 ESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGG----NHTENVGEAAVTQVE 376
E+ + Q+E N+ A + R LE + + H ++V E Q++
Sbjct: 1158 EAGG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG-EQID 1214
Query: 377 EQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEK----------EFTNQEAA 426
S+ + DD + E + +LEK E ++E
Sbjct: 1215 NLQRVKQKLEKEKSEMKMEIDD---LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEE 1271
Query: 427 EPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQN 486
+ + + + + GR E GE + DEK Q + G Q
Sbjct: 1272 QQRLINDLTAQRGR-LQTESGEFSRQLDEKEALVS------------QLSRGKQAFTQQI 1318
Query: 487 EPLDMKEPDEEKS-DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD 545
E L + +E K+ + AL SS+ +++ ++++ E+ ++++ L+ NT+
Sbjct: 1319 EELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQ-----ESKAELQRALSKANTE 1373
Query: 546 LSEIKEEEQVKSTDRKSAV-EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 604
+++ + + + + R + EA+ ++ + + + N C K K +L E
Sbjct: 1374 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK--QRLQNEV 1431
Query: 605 DDVQTAAEEVLADGDTLD 622
+D+ E A LD
Sbjct: 1432 EDLMLDVERTNAACAALD 1449
Score = 31.6 bits (70), Expect = 2.8
Identities = 38/183 (20%), Positives = 75/183 (40%), Gaps = 18/183 (9%)
Query: 22 LAEARLAAKRAARAEAREIRMKELERQQKEVE---ERPEKDFTEKGSRNMPGLSAATLAS 78
L EAR A ++A +A M E +++++ ER +K+ + L A +
Sbjct: 1751 LQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLA 1810
Query: 79 LGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD- 137
L G G I EA +RE++ + +++ +A+ + + YQ +
Sbjct: 1811 LKG-------GKKQIQ-KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEE 1862
Query: 138 ------TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEM 191
L+D++ +L+ ++ +RQ EE ++ LQ + E +E E
Sbjct: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQ 1922
Query: 192 LEK 194
+ K
Sbjct: 1923 VNK 1925
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 55.1 bits (131), Expect = 2e-07
Identities = 72/460 (15%), Positives = 163/460 (35%), Gaps = 21/460 (4%)
Query: 289 NTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTP 348
++ D +S D++ + G+ + +S SS +++ S++ + D
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN---- 886
Query: 349 LEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQEL 408
E SN D N +++ + + + S +S D+ + +
Sbjct: 887 -ESSNSSDSSDSSNSSDS-------DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 409 ETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAG 468
S+ S + +N + ++S++ ++ + + + D S +
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 469 TEGNCQEATGPS-TVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPV 527
N +++ S + D+ N D S ++ DSS + + +
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 528 PVETLKDVKKEL-TYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENV 586
D + ++D S+ E + S ++ +++ +++SS++
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 587 DCPENPKIKLDGKLDQEGDDVQTAAE--EVLADGDTLDFED--DTVQSSGPRAGGEELDE 642
D N D + D +++ + D+ D D D+ SS + D
Sbjct: 1119 DS-SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 643 GVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE--SPSQDISDACEAESTERCEMSEHP 700
+ D++ ++ SS + S+ +D + S S D SD+ ++ + S
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237
Query: 701 SQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGN 740
S + + SNS ++ D S N ES ++ GN
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277
Score = 52.0 bits (123), Expect = 2e-06
Identities = 74/506 (14%), Positives = 169/506 (33%), Gaps = 19/506 (3%)
Query: 265 TEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSS 324
+E + D+ D D + +N++ SS + + + + + S SS
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 325 LPENTVQVESNEVMGAPDDRTRTPLEPSNCW----SDLDGGNHTENVGEAAVTQVEEQAG 380
+++ S+E + D + S+ SD D N +++ + + + +
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 381 TVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPA---HSTE 437
+ S S D+ D + S+ S + +N + + +S++
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 438 VGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEE 497
+ + + + D S + + +++ S D+ N D
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868
Query: 498 KSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEE-EQVK 556
S + DSS N+ + + ++D S + E
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 557 STDRKSAVEAQN--EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 614
S+D ++ ++ N + +++ +++SS + D N D D ++
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS-SNSSDSSDSNSSDSSDSSNSSDSSD 987
Query: 615 LADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPE 674
+D D+ SS + D + D++ ++ SS + S+ +D +
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 675 --------HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPG 726
+ S S D SD+ ++ + S S++ + SNS ++ D S
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Query: 727 HFNPESREDTRGGNEKGKSKEDCTMS 752
+ D+ + S + S
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Score = 51.6 bits (122), Expect = 3e-06
Identities = 55/315 (17%), Positives = 118/315 (37%), Gaps = 19/315 (6%)
Query: 441 DHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSD 500
D N E + R + ++ + GN ++ G D+ + D SD
Sbjct: 476 DANSESDNNSSSRGDASYNSD----ESKDNGNGSDSKGAEDDDSDSTS------DTNNSD 525
Query: 501 QQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDR 560
G + + K+ K K S + ++D S+ S+D
Sbjct: 526 SNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585
Query: 561 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQ---EGDDVQTAAEEVLAD 617
S+ + ++ +++ +++SS++ D ++ D K D E D + ++ +D
Sbjct: 586 DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS-DSKSDSSKSESDSSDSDSKSDSSD 644
Query: 618 GDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHES 677
++ D D++ SS D + D++ ++ SS + S+ +D + S
Sbjct: 645 SNSSDSSDNS-DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD----SSNSS 699
Query: 678 PSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTR 737
S D SD+ +++S++ + S S + S+S ++ + S N D+
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759
Query: 738 GGNEKGKSKEDCTMS 752
+ S + S
Sbjct: 760 DSSNSSDSSDSSDSS 774
Score = 47.8 bits (112), Expect = 4e-05
Identities = 72/558 (12%), Positives = 186/558 (33%), Gaps = 22/558 (3%)
Query: 200 NSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKR 259
+S+ + + ++SD+ ++ + + + + D + +S+ + N ++
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739
Query: 260 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 319
+ + D D ++ D S D++ + + + S
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN-----SSDSNDSSNSSDS 794
Query: 320 LESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV-----GEAAVTQ 374
+SS+ +++ +S++ + D + + SN D N +++ + + +
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 375 VEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAH 434
++ + S S D+ D E S+ S ++ ++++
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 435 STEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEP 494
S + E + + S + N +++ S ++ D
Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 495 DEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQ 554
D S ++ DSS + + D + ++D S +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD-----SSNSSDSSNSSDSSN 1029
Query: 555 VKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 614
+ S ++ +++ ++ SS++ D ++ D + D ++E
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS----DSSDSSDSSDSSDSSES- 1084
Query: 615 LADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPE 674
+D D+ SS + D + D++ ++ SS + S+ +D +
Sbjct: 1085 -SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 675 HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESRE 734
S S + SD+ ++ + S S + + SNS ++ D S +
Sbjct: 1144 -SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 735 DTRGGNEKGKSKEDCTMS 752
D+ ++ S + S
Sbjct: 1203 DSSDSSDSSDSSDSSDSS 1220
Score = 47.0 bits (110), Expect = 7e-05
Identities = 106/599 (17%), Positives = 212/599 (35%), Gaps = 65/599 (10%)
Query: 205 TNGETSDTLNN--VGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 262
TNG T N VG G E++ ++ G G + + ++EI+ N + E
Sbjct: 154 TNGNTDKNTQNGDVGDAGHN----EDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEG- 208
Query: 263 HNTEKEQHTEDTVKDCVDIEVFP-----AGENTEDQKSSEDTAPFLGTLAGATYEEQVQS 317
+ +E + EV P AG + D S + A E++
Sbjct: 209 NTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAG 268
Query: 318 QILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNC--WSDLDGGN--HTENVGEAAVT 373
+SS N + + + G DD + + S+ + D +G H E G+
Sbjct: 269 NGKDSS----NNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSK 324
Query: 374 QVEEQAGTVASCPLGHSDDT--VYHDDKCMVE--VPQELET-STGHSLEKEFTNQEAAEP 428
E AG +DT + H + VE + +E ET + G S +K + +
Sbjct: 325 SEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSG 384
Query: 429 KEVPAHSTEVGRDHNEEEGEETGLRDEKPIKT-------EVPG-----------SPAGTE 470
G + E++G+ + + +KT E PG S G++
Sbjct: 385 NRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSD 444
Query: 471 GNCQ------------EATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKK 518
N + P++ D N D + S +G+A +S + N
Sbjct: 445 SNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNG 504
Query: 519 KNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKI 578
+ K ++ D + N + + ++ + + + + ++ +++
Sbjct: 505 SDSKGAEDDDSDSTSDTNN--SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562
Query: 579 AAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFED-----DTVQSSGP 633
+++SS++ N D D + + + D+ D D D+ SS
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622
Query: 634 RAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTER 693
++ + + + ++K D + +S + D+ + + S S D SD+ ++ S+
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682
Query: 694 CEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKEDCTMS 752
S + S + + SNS E+ D S + +S ++ S + S
Sbjct: 683 ---SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Score = 43.9 bits (102), Expect = 6e-04
Identities = 56/369 (15%), Positives = 130/369 (35%), Gaps = 15/369 (4%)
Query: 392 DTVYHDDKCMV-EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET 450
D+ DDK M + P + S G+ ++ ++ + +S E +D+ +
Sbjct: 451 DSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE-SKDNGNGSDSKG 509
Query: 451 GLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQ 510
D+ ++ S + GN + D+ D + D S ++ DSS
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS-DSGKGKSDSSDSDSSDSSNSSDSSDSSD 568
Query: 511 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEE----EQVKSTDRKS---- 562
+ + + S D + ++D S+ + + S+D KS
Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 563 --AVEAQNEVTENPKQKIAAESSENVDCPE--NPKIKLDGKLDQEGDDVQTAAEEVLADG 618
+ + ++ + +++SS+N D + N D + D ++++ +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 619 DTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESP 678
+ + S + + D + D++ + + S S D+ + S
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 679 SQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRG 738
S + SD+ ++ + S S + + SNS +++D S N ++
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 739 GNEKGKSKE 747
++ S +
Sbjct: 809 SSDSSDSSD 817
Score = 43.5 bits (101), Expect = 7e-04
Identities = 72/560 (12%), Positives = 195/560 (34%), Gaps = 25/560 (4%)
Query: 200 NSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKR 259
NS+ NG + N+ G K + ++ S+ +S+ + +
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS-------- 574
Query: 260 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 319
N+ + + D+ D D + +++ SS+ + + + + + + S
Sbjct: 575 ----NSSSDSDSSDS--DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 320 LESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA 379
ES S ++ S+ D + + + SN + D + +++ ++ + +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSS-DSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687
Query: 380 GTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVG 439
+ S +S ++ D + ++S +S + + +N + + S++
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747
Query: 440 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 499
N + ++ ++ S ++ + + S+ + + D S
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD-SSNSSDSSNS 806
Query: 500 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 559
++ DSS + N + S + + +D + S+D
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 560 RKSAVEAQN-----EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 614
+ ++ N + +++ + +++SS++ + ++ D + + E
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 615 LADGDTLDFED--DTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTL 672
D + D ++ SS D + D++ ++ S+ ++ S D+ +
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD--SSDSSNSSD 984
Query: 673 PEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPES 732
S S D SD+ ++ ++ S S + + SNS ++ + S +
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSD 1044
Query: 733 REDTRGGNEKGKSKEDCTMS 752
D+ ++ S + S
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSS 1064
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 55.1 bits (131), Expect = 2e-07
Identities = 116/585 (19%), Positives = 215/585 (36%), Gaps = 103/585 (17%)
Query: 23 AEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGT 82
A +RL +R R E+R+ E PE D +K P L ++ +A+
Sbjct: 82 AVSRLGGERRTRRESRQ-------------ESDPEDDDVKK-----PALQSSVVATSKER 123
Query: 83 SSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 142
+ R D ++ + R I L +K+K+ S + +K +++
Sbjct: 124 TRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQE--STVATERQKRR--------QEI 173
Query: 143 LLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSE 202
+LE Q E R+Q E + +E E+ A + + E K L Q +E +H +
Sbjct: 174 EQKLEVQAEEERKQVENERRELFEERRAKQ-TELRLLEQKVELAQLQEEWNEHNAKIIKY 232
Query: 203 IATNG-------------------ETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRA 243
I T E S N ++G E++N +++ R
Sbjct: 233 IRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARP----RRQ 288
Query: 244 SEVEVKNEIVAN---VGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTA 300
S E ++++V N ++E ++E+ E+T D+E+ AGE E +
Sbjct: 289 SMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKE------I 342
Query: 301 PFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDG 360
+ + A EE+ Q Q +E E V+ + P++ +D
Sbjct: 343 AIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEE-------------VMDV 389
Query: 361 GNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEF 420
ENV Q + V S P E E S E EF
Sbjct: 390 LEMVENVKHVIADQEVMETNRVESVE------------------PSENEASKELEPEMEF 431
Query: 421 TNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS 480
+ E K + V E+E EE ++ +P V ++ Q
Sbjct: 432 EIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQ------ 485
Query: 481 TVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELT 540
+ +Q++P+ +P + D L + + T+ + ++K PVE++K + +
Sbjct: 486 -LQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKD-FPVESVKLTEVPVE 543
Query: 541 YQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSEN 585
T E K + + +S +S A+N+ +++ + ++ SS +
Sbjct: 544 PVLTVHPESKSKTKTRS---RSRGRARNKTSKSRSRSSSSSSSSS 585
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 54.7 bits (130), Expect = 3e-07
Identities = 73/309 (23%), Positives = 124/309 (40%), Gaps = 51/309 (16%)
Query: 397 DDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV-----PAHSTE--VGRDHNEEEGEE 449
+ C E +++E G E T AA+ E+ PA T+ G+ NE E
Sbjct: 8 ESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTE 67
Query: 450 TGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSS 509
+G +++ P + G A +G EA G DE K + Q EA
Sbjct: 68 SGKQEKAPAED---GMSAELQG---EANGL---------------DEVKVESQREAGGKE 106
Query: 510 QKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNE 569
+ + KK+ +K+++ V + + K+E SE KE E+ +ST + ++ +
Sbjct: 107 DAEAELKKEDGEKEETTVGSQEMTGRKEETK------SEPKEAEEKEST-----LASEKQ 155
Query: 570 VTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQ 629
E + K ES + D N + K + K E +D +TA++E G + + +
Sbjct: 156 KAEEKEAK--PESGQKADA--NDRDKPEPKATVEEEDAKTASQE--ETGQRKECSTEPKE 209
Query: 630 SSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAE 689
+ E + V +D AK + P EP ++ + E ++ DA EAE
Sbjct: 210 KATDEEAKAESQKAVVEDEAKAE------PKEPDGKEEAKHGAKEEADAKEEAEDAEEAE 263
Query: 690 STERCEMSE 698
E E
Sbjct: 264 PGSPSEEQE 272
Score = 52.4 bits (124), Expect = 2e-06
Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 26/297 (8%)
Query: 405 PQELETSTGHSLEKEFTNQEAAEPKEVPAH---STEVGRDHN-------EEEGEETGLRD 454
P E T E E+ + ++ PA S E+ + N E + E G D
Sbjct: 48 PAEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKED 107
Query: 455 EKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTK 514
+ + G T QE TG +T++EP + +E + + ++ +A + K
Sbjct: 108 AEAELKKEDGEKEETTVGSQEMTGRKE-ETKSEPKEAEEKESTLASEKQKAEEKEAKPES 166
Query: 515 NKKKKNKKKKSPVPVETLK--DVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTE 572
+K + P P T++ D K + E E + K+TD ++ E+Q V E
Sbjct: 167 GQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVE 226
Query: 573 NPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSG 632
+ + E + K + D K +E +D + A ++ D E + +G
Sbjct: 227 DEAKAEPKEPDGKEEAKHGAKEEADAK--EEAEDAEEAEPGSPSEEQEQDVEKEPEGGAG 284
Query: 633 P-RAGGEELDEGVAKD--NAKIDG-------ATQSSPAEPKSEDADRCTLPEHESPS 679
+ EE E + N DG + Q+SP+ +S +D P ESPS
Sbjct: 285 VIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPP-ESPS 340
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 54.3 bits (129), Expect = 4e-07
Identities = 133/632 (21%), Positives = 259/632 (40%), Gaps = 78/632 (12%)
Query: 7 AQSREIDCLSPEAQKLAE--ARLAAKRAARAEAREIRMKELERQQKEVE---------ER 55
A ++ LS E L E ++L ++ + EA + + +L+ ++ +V E+
Sbjct: 974 ATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQ 1033
Query: 56 PEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKY 115
D +GS A L + R+ GD +S + SI ++++ ++EEK
Sbjct: 1034 QTDDL--EGSLEQEKKLRADLER----AKRKLEGDLKMS---QESIMDLENDKQQIEEKL 1084
Query: 116 KKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQ 175
KK +QL ++D + L+ ++++ E + + EE +E E E + ++
Sbjct: 1085 KKKEFELSQL-------QAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIE 1137
Query: 176 FQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKST 235
Q +++ L++ E LE+ +++I N + + + EE
Sbjct: 1138 KQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKM------RRDLEEATLQHEA 1191
Query: 236 GDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTED-QK 294
TL + + + VA +G E + N ++ + + K + +E+ N E K
Sbjct: 1192 TAATLRKK-----QADSVAELG--EQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSK 1244
Query: 295 SSEDTAPFLGTLAGATYE----EQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLE 350
S + T+ E ++ Q+Q++ ++ + +Q ++ E+ +++ +
Sbjct: 1245 SKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQ 1304
Query: 351 PSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM---VEVPQE 407
+ L T+ + E Q+EE+ T A + H+ + HD + E QE
Sbjct: 1305 LTKSKQAL-----TQQL-EELKRQMEEE--TKAKNAMAHALQSSRHDCDLLREQYEEEQE 1356
Query: 408 LETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPA 467
+ +L K N E A+ + E EE EE +K + + +
Sbjct: 1357 AKAELQRALSK--ANSEVAQWRT----KYETDAIQRTEELEEA----KKKLAQRLQEAEE 1406
Query: 468 GTE-GNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSP 526
TE N + A+ T ++ D E+S LD Q+ + K+K
Sbjct: 1407 NTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDE 1466
Query: 527 VPVETLKDVKKELTYQNTDLSEIKE--EEQVK--STDRKSAVEAQNEVTENPKQKIAAES 582
E L+ +KE +T+L +++ EE V T R+ Q E+++ +Q AE+
Sbjct: 1467 SQAE-LEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQ--IAET 1523
Query: 583 SENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 614
+N+ E K KL ++QE D+Q A EEV
Sbjct: 1524 GKNLQEAEKTK-KL---VEQEKSDLQVALEEV 1551
Score = 32.7 bits (73), Expect = 1.3
Identities = 46/227 (20%), Positives = 92/227 (40%), Gaps = 45/227 (19%)
Query: 6 AAQSREIDC--LSPEAQKLAEARLAAKRAARAEAREI-------------RMKELERQQK 50
A QS DC L + ++ EA+ +RA E+ R +ELE +K
Sbjct: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395
Query: 51 EVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASI--------- 101
++ +R ++ + N + ASL T R + D E S
Sbjct: 1396 KLAQRLQEAEENTETAN------SKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKK 1449
Query: 102 ------------REIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLE---L 146
+++ +S AE+E K++ + +L + + VD L+ + E L
Sbjct: 1450 QRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNL 1509
Query: 147 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE 193
+E++++ Q E K + + +++ + ++++ AL++ E LE
Sbjct: 1510 QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLE 1556
Score = 30.8 bits (68), Expect = 4.8
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 25/163 (15%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML-----------LEL 146
+ I ++ + +AE + ++A + ++ EK++ ++ ++ L LEL
Sbjct: 1510 QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLEL 1569
Query: 147 EEQLAESRRQYEEKNKEFEREKH--------AHSILQFQFAEVKEALKQREEM---LEKH 195
+ +E R+ EK++E E+ K S+L + +AL+ +++M L +
Sbjct: 1570 SQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEM 1629
Query: 196 GIILNSEIATNGETSDTLNNVGYQGPTKMTKEEL-NALKSTGD 237
I L ET L V QG K ++ L +AL+S D
Sbjct: 1630 EIQLGHSNRQMAETQKHLRTV--QGQLKDSQLHLDDALRSNED 1670
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 53.1 bits (126), Expect = 9e-07
Identities = 59/252 (23%), Positives = 109/252 (43%), Gaps = 21/252 (8%)
Query: 401 MVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKT 460
+V V E++ S K T + E + + + V E EE + K +
Sbjct: 27 LVPVTPEVKPKRTSSSRKMKTKSDMME-ENIDTSAQAVAETKQEAVVEEDYNENAKNGEA 85
Query: 461 EVPGSPAGT-------EGNCQEATGPS-------TVDTQNEPLDMKEPDEEKSDQQGEA- 505
++ +PA E N ++AT + +NE D KE +E++++++GEA
Sbjct: 86 KITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
Query: 506 -LDSSQK-KTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSA 563
D +K + K+ KN +K E K E N + + K E++ + DRK
Sbjct: 146 KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Query: 564 VEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAE-EVLADGDTLD 622
+ + E+ K+K + ++V E+ K + DGK D+ G++ + E E L + +
Sbjct: 206 GDGKE--NEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK 263
Query: 623 FEDDTVQSSGPR 634
ED+ + G +
Sbjct: 264 EEDEIKEDDGKK 275
Score = 34.3 bits (77), Expect = 0.44
Identities = 36/196 (18%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 561 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIK---------LDGKLDQEGDDVQTAA 611
K Q ++ + PK++ A S+ V P P++K + K D +++ T+A
Sbjct: 3 KRKAAGQGDMRQEPKRRSARLSAMLV--PVTPEVKPKRTSSSRKMKTKSDMMEENIDTSA 60
Query: 612 EEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCT 671
+ V E+D +++ + G ++ E A + ++ E EDA
Sbjct: 61 QAVAETKQEAVVEEDYNENA--KNGEAKITEAPASEKEIVE------VKEENIEDATEKG 112
Query: 672 LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 731
+ E+ + ++ + E + + + +E + ++ D E+ G E G E
Sbjct: 113 GEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKE 172
Query: 732 SREDTRGGNEKGKSKE 747
+ +G + KG ++
Sbjct: 173 KEDGKKGEDGKGNGED 188
Score = 32.7 bits (73), Expect = 1.3
Identities = 53/239 (22%), Positives = 94/239 (39%), Gaps = 35/239 (14%)
Query: 479 PSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQK---KTK---------NKKKKNKKKK-- 524
P T + + + + KSD E +D+S + +TK N+ KN + K
Sbjct: 29 PVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKIT 88
Query: 525 -SPVPVETLKDVKKELTYQNTD---------LSEIK-EEEQVKSTD---RKSAVEAQNEV 570
+P + + +VK+E T+ +E+K EEE K + + EA E
Sbjct: 89 EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
Query: 571 TENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQS 630
+ ++ E + E+ K K DGK +G+D + E+ G+ E+D ++
Sbjct: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGK---KGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Query: 631 SGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAE 689
G+E ++G K + K + E + ED E ++ D E E
Sbjct: 206 ----GDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260
Score = 30.0 bits (66), Expect = 8.2
Identities = 44/192 (22%), Positives = 73/192 (38%), Gaps = 14/192 (7%)
Query: 15 LSPEAQKLAEARLAA-------KRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRN 67
+ AQ +AE + A + A EA+ E++ EV+E +D TEKG
Sbjct: 56 IDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEK 115
Query: 68 MPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDN 127
A A + + + + + + +E KD E + K K +
Sbjct: 116 ----KEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAK 171
Query: 128 EKTNFMYQVD---TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 184
EK + D +D + E++ E R+ KE E K + + +VKE
Sbjct: 172 EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKED 231
Query: 185 LKQREEMLEKHG 196
K+RE+ E G
Sbjct: 232 EKEREDGKEDEG 243
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 53.1 bits (126), Expect = 9e-07
Identities = 125/646 (19%), Positives = 264/646 (40%), Gaps = 76/646 (11%)
Query: 7 AQSREIDCLSPEAQKLAE--ARLAAKRAARAEAREIRMKELERQQKEVEERPE-KDFTEK 63
A ++ L+ E L E A+L ++ A EA + + +L+ ++ +V + K E+
Sbjct: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQ 1033
Query: 64 GSRNMPGL--SAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS 121
++ G L + R+ GD ++ + S + ++ ++ EK KK
Sbjct: 1034 QVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLA---QESTMDTENDKQQLNEKLKKK--- 1087
Query: 122 NAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEV 181
+ E +N +++ + + ++L++++ E + + EE +E E E+ + + + Q +++
Sbjct: 1088 ----EFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1143
Query: 182 KEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG 241
L++ E LE+ G +++I N + + K + +ST
Sbjct: 1144 SRELEEISERLEEAGGATSAQIEMNKKRE-----------AEFQKMRRDLEESTLQHEAT 1192
Query: 242 RASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTED-QKSSEDTA 300
A+ + + VA +G++ + + ++ + + K + +E+ N E K+ +
Sbjct: 1193 AAALRKKHADSVAELGEQ--IDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFE 1250
Query: 301 PFLGTLAGATYE----EQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWS 356
TL E E+ Q +++ S + + ES E D++ S
Sbjct: 1251 KMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMV-------S 1303
Query: 357 DLDGGNH--TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM---VEVPQELETS 411
L G T+ + E Q+EE+ T A L H+ + HD + E QE +
Sbjct: 1304 QLSRGKQAFTQQIEELK-RQLEEE--TKAKSTLAHALQSARHDCDLLREQYEEEQEAKAE 1360
Query: 412 TGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET---GLRDEKPIKTEVPGSPAG 468
+ K N E A+ + + + R EE ++ L+D + V A
Sbjct: 1361 LQRGMSK--ANSEVAQWR-TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCAS 1417
Query: 469 ---TEGNCQEATGPSTVDTQNE-----PLDMKEPD--------EEKSDQQGEALDSSQKK 512
T+ Q +D + LD K+ + ++K ++ L++SQK+
Sbjct: 1418 LEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKE 1477
Query: 513 TKNK-----KKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQ 567
+++ K KN ++S +ETLK K L + +DL+E + E K V+ Q
Sbjct: 1478 SRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTE-QIAEGGKHIHELEKVKKQ 1536
Query: 568 NEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEE 613
+ ++ Q E+ +++ E +++ +L+Q ++ E
Sbjct: 1537 LDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAE 1582
Score = 48.5 bits (114), Expect = 2e-05
Identities = 129/666 (19%), Positives = 251/666 (37%), Gaps = 115/666 (17%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDF 60
+T +++D L ++ + + +RA R ++++ + E +++ +
Sbjct: 1024 LTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEK 1083
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMV 120
+K M L + +++I + I+E++ + E+EE+ +
Sbjct: 1084 LKKKEFEMSNLQGKI------------EDEQALAIQLQKKIKELQARIEELEEEIEAERA 1131
Query: 121 SNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAE 180
S A+ + ++++ +++ + + L E + +++ EF++ + Q
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEA 1191
Query: 181 VKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL 240
AL+ +KH +A GE D+L V K+ KE+ D
Sbjct: 1192 TAAALR------KKHA----DSVAELGEQIDSLQRV----KQKLEKEKSELKMEIND--- 1234
Query: 241 GRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTA 300
AS +E ++ AN K C EDQ S T
Sbjct: 1235 -LASNMETVSKAKANFEKM------------------C---------RTLEDQLSEIKT- 1265
Query: 301 PFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDG 360
+E+ Q +++ S + + ES E D++ S L
Sbjct: 1266 -----------KEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMV-------SQLSR 1307
Query: 361 GNH--TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHD-DKCMVEVPQELETSTGHSLE 417
G T+ + E Q+EE+ T A L H+ + HD D + +E E
Sbjct: 1308 GKQAFTQQI-EELKRQLEEE--TKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRG 1364
Query: 418 KEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEE---TGLRDEKPIKTEVPGSPAGTEGNCQ 474
N E A+ + + + R EE ++ L+D + V A E Q
Sbjct: 1365 MSKANSEVAQWR-TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQ 1423
Query: 475 EATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKD 534
QNE D+ D E+S+ ALD Q+ + K+K E L+
Sbjct: 1424 R--------LQNEVEDLM-IDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAE-LEA 1473
Query: 535 VKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIA------AESSENVDC 588
+KE +T+L ++K + +S D ++ +N +N +Q+I+ AE +++
Sbjct: 1474 SQKESRSLSTELFKVKNAYE-ESLDHLETLKREN---KNLQQEISDLTEQIAEGGKHIHE 1529
Query: 589 PENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAG--GEELDEGVAK 646
E K+ +LD E ++QT+ EE A +L+ E+ + E+D +A+
Sbjct: 1530 LE----KVKKQLDHEKSELQTSLEEAEA---SLEHEEGKILRIQLELNQVKSEIDRKIAE 1582
Query: 647 DNAKID 652
+ ++D
Sbjct: 1583 KDEELD 1588
Score = 33.9 bits (76), Expect = 0.57
Identities = 99/529 (18%), Positives = 201/529 (37%), Gaps = 76/529 (14%)
Query: 61 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISI------DTEASIREIKDSLAEVEEK 114
TEK NM T L T ++R + + D + ++ D+LA+ EE+
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEER 908
Query: 115 YKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSIL 174
+ + + QL+ + + +V + E+ +L +R+ E++ E +++ L
Sbjct: 909 CDQLIKTKIQLEAK----IKEVTERAEDEEEINAELTAKKRKLEDECSELKKD---IDDL 961
Query: 175 QFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKS 234
+ A+V++ E ++ L E+A ET K+TKE+ AL+
Sbjct: 962 ELTLAKVEKEKHATENKVKN----LTEEMAGLDETI-----------AKLTKEK-KALQE 1005
Query: 235 TGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIE---------VFP 285
TL E K + + + E E K C+D+E +
Sbjct: 1006 AHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKL 1065
Query: 286 AGENTEDQKSSEDTAP--------FLGTLAGATYEE-----QVQSQILE-SSSLPENTVQ 331
A E+T D ++ + + L G +E Q+Q +I E + + E +
Sbjct: 1066 AQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEE 1125
Query: 332 VESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAG-TVASCPLGHS 390
+E+ A ++ R+ L E + E ++EE G T A +
Sbjct: 1126 IEAERASRAKAEKQRSDL-----------SRELEEISE----RLEEAGGATSAQIEMNKK 1170
Query: 391 DDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET 450
+ + + +E +T +L K+ + A +++ + + E+ +
Sbjct: 1171 REAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKM 1230
Query: 451 GLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQ 510
+ D V + A E C+ T++ Q + KE ++++ + A ++
Sbjct: 1231 EINDLASNMETVSKAKANFEKMCR------TLEDQLSEIKTKEEEQQRLINELSA-QKAR 1283
Query: 511 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLS-EIKEEEQVKST 558
T++ + + + V L K+ T Q +L +++EE + KST
Sbjct: 1284 LHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKST 1332
Score = 30.0 bits (66), Expect = 8.2
Identities = 47/219 (21%), Positives = 91/219 (41%), Gaps = 45/219 (20%)
Query: 98 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML-----------LEL 146
+ I ++ + +AE + + QLD+EK+ ++ + L LEL
Sbjct: 1510 QQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLEL 1569
Query: 147 EEQLAESRRQYEEKNKEFEREKHAH--------SILQFQFAEVKEALKQREEM---LEKH 195
+ +E R+ EK++E ++ K H S L + +AL+ +++M L +
Sbjct: 1570 NQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEM 1629
Query: 196 GIILNSEIATNGETSDTLNNV-GYQGPTKMT--------------KEELNALKSTGDGTL 240
I LN N + ++ L N+ QG K T KE+L ++ +
Sbjct: 1630 EIQLNH---ANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQ 1686
Query: 241 GRASEVEV---KNEIVANVGKREILHNTEKEQ--HTEDT 274
E+ + E + ++E+L +E+ Q HT++T
Sbjct: 1687 AEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNT 1725
Score = 30.0 bits (66), Expect = 8.2
Identities = 42/182 (23%), Positives = 74/182 (40%), Gaps = 20/182 (10%)
Query: 24 EARLAAKRAARAEAREIRMKELERQQKEVE---ERPEKDFTEKGSRNMPGLSAATLASLG 80
EAR A ++A +A M E +++++ ER +K+ + L A +L
Sbjct: 1751 EARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALK 1810
Query: 81 GTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKT-NFMYQVD-- 137
G G I EA +RE+ +S E E+K+ V + + YQ +
Sbjct: 1811 G-------GKKQIQ-KLEARVREL-ESEVESEQKHNVEAVKGLRKHERRVKELTYQTEED 1861
Query: 138 -----TLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML 192
L+D++ +L+ ++ +RQ EE ++ LQ + E KE E +
Sbjct: 1862 RKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV 1921
Query: 193 EK 194
K
Sbjct: 1922 NK 1923
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 52.0 bits (123), Expect = 2e-06
Identities = 131/643 (20%), Positives = 248/643 (38%), Gaps = 111/643 (17%)
Query: 20 QKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASL 79
QKL E LA K + + R +E + Q K E+ + ++
Sbjct: 482 QKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEY------------------- 522
Query: 80 GGTSSRRGSGDTSISIDTEASIREIKDSLAEVE-EKYKKAMVSNAQLDNEKTNFMYQVDT 138
+ I E +E ++SLA E E KKA+++ ++ N+ + + +T
Sbjct: 523 -------------LKISQE---KEQQESLALEELELQKKAILTESE--NKLRDLQQEAET 564
Query: 139 LKDMLLELEEQLAESRRQYEEKNKEF----EREKHAHSILQFQFAEVKEALKQREEMLEK 194
+ +LELE L +S ++ + ++K+ E EK+ H+ K+ M+EK
Sbjct: 565 YRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN-------------KEITVMVEK 611
Query: 195 HGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKN-EIV 253
H +E+ + D L Q + + E+ L+ + + E +K+ EI+
Sbjct: 612 H----KTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCE----QEKETLLKDKEII 663
Query: 254 ANVGKREILHNTEKEQHTEDTVKDCVDIE---VFPAGENTEDQKS--SEDTAPFLGTLAG 308
E+ T ++ + T + + E V A E++ S + T L
Sbjct: 664 FQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEA 723
Query: 309 ATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDL-DGGNHTENV 367
E++ Q S + E+ V ++ E D + L L + H EN+
Sbjct: 724 KMDEQKNHHQQQVDSIIKEHEVSIQRTE-KALKDQINQLELLLKERDKHLKEHQAHVENL 782
Query: 368 ------GEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFT 421
E + Q + S + T ++++ + L+ T L +
Sbjct: 783 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV 842
Query: 422 NQEAAEPKEV----PAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEAT 477
+ A+ K+V AH +V + E + + + + T+V S QE T
Sbjct: 843 AEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQT 902
Query: 478 GPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQK-------------KTKNKKKKNKKKK 524
V+ +N L M+E +++ + + L + + K + KK + K+K
Sbjct: 903 KQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQK 962
Query: 525 SPVPVETLK--------DVKKELTYQNTDLSEIKEEEQVKSTDRKSA-----VEAQNEVT 571
+ ETLK +KKEL +LS+ +++ K + A +A + +
Sbjct: 963 AKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLE 1022
Query: 572 ENPKQKIAAESSENVDCPE-NPKIKL-DGKLDQEGDDVQTAAE 612
N K++I ES V E N I + + KL+Q+ +++Q E
Sbjct: 1023 TNQKEQI--ESLTEVHRRELNDVISIWEKKLNQQAEELQEIHE 1063
Score = 38.1 bits (87), Expect = 0.030
Identities = 108/592 (18%), Positives = 236/592 (39%), Gaps = 88/592 (14%)
Query: 44 ELERQQKEVEERPEKDFTEKG---SRNMPGLSAATLASLGGTSSRRGSGDTSIS--IDTE 98
E+E+ +++ E+ E +K ++ ++ TL L + S + +S +
Sbjct: 641 EMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR 700
Query: 99 ASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTL----KDMLLELEEQLAESR 154
+ E L + +K K+ + A++D +K + QVD++ + + E+ L +
Sbjct: 701 HKLEEELSVLKDQTDKMKQEL--EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQI 758
Query: 155 RQYEEKNKEFEREKHAHSI-LQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTL 213
Q E KE ++ H ++ A++K + + ++ K + + + AT+ +T
Sbjct: 759 NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK--- 815
Query: 214 NNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTED 273
Y+ +++L L++ + +EVE + + V TE + H
Sbjct: 816 ---AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVC----------TELDAHK-- 860
Query: 274 TVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQS--QILESSSLPENTVQ 331
I+V + E Q S E++V+S Q+ ES N Q
Sbjct: 861 -------IQVQDLMQQLEKQNSE--------------MEQKVKSLTQVYESKLEDGNKEQ 899
Query: 332 VESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSD 391
++ +++ +E N + G E +E + + L
Sbjct: 900 EQTKQIL----------VEKENMILQMREGQKKEIEILTQKLSAKEDSIHI----LNEEY 945
Query: 392 DTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETG 451
+T + + + +E ++ +L+K+ +QEA KE+ + E+ + E++
Sbjct: 946 ETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ--KEKQFNAKM 1003
Query: 452 LRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSS-- 509
L + + + + E N +E T + E D+ E+K +QQ E L
Sbjct: 1004 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHE 1063
Query: 510 -QKKTKNKKKKNKKKKSPVPVETLKDVKKELTY-------QNTDLSEIKEEEQVKSTDRK 561
Q + K ++ K+K + +++ KE+T+ Q+T L+E++E+ + KS
Sbjct: 1064 IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVN 1123
Query: 562 SAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEE 613
S + + ++ + E ++ N +K + L ++ +++ AEE
Sbjct: 1124 SLAQDETKLKAH---------LEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1166
Score = 35.0 bits (79), Expect = 0.26
Identities = 110/549 (20%), Positives = 195/549 (35%), Gaps = 76/549 (13%)
Query: 90 DTSISIDTEA-----SIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLL 144
D S +DT + ++ ++ D + E KKA Q N Q++
Sbjct: 1416 DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAY 1475
Query: 145 ELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA 204
E +EQ+ + + +++NK F+ L+ + + K ++++E LE L S+ A
Sbjct: 1476 EKDEQINLLKEELDQQNKRFD-------CLKGEMEDDKSKMEKKESNLETE---LKSQTA 1525
Query: 205 TNGETSD--------------TLNNVGYQGPT--KMTKEELNALKSTGDGTLGRASEVEV 248
E D L N Q K ++L + G+ R E E
Sbjct: 1526 RIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEE 1585
Query: 249 K-----NEIVA-----NVGKREILHNTEKEQHTEDTVKDCVD-IEVFPAGENTE-DQKSS 296
K N++ + K+E+ H + E+ +K D +E A + E +K+
Sbjct: 1586 KILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE 1645
Query: 297 EDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNE---------VMGAPDDRTRT 347
+ A L E++ Q + S L E +++ E + ++ T
Sbjct: 1646 QKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSET 1705
Query: 348 PLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQE 407
+ P + + E + V + E+ +V L +K + V QE
Sbjct: 1706 LIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEK-------EKLLQRVGQE 1758
Query: 408 LETSTGHSLEKEFTNQE---AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPG 464
E + E QE E E H + H +EE EE + + V
Sbjct: 1759 KEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHV-- 1816
Query: 465 SPAGTEGNCQEATGPSTV-DTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKK 523
G + N Q V D + L KE + +Q+ + LDS + K + ++
Sbjct: 1817 EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEE 1876
Query: 524 KSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKS----TDRKSAVEAQNE-------VTE 572
+ + + + + T+L E EE+ KS S +EAQ+ E
Sbjct: 1877 LTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAE 1936
Query: 573 NPKQKIAAE 581
KQK+ E
Sbjct: 1937 REKQKLGKE 1945
Score = 30.0 bits (66), Expect = 8.2
Identities = 44/214 (20%), Positives = 83/214 (38%), Gaps = 29/214 (13%)
Query: 511 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEV 570
+ KN ++ ++ K V ET + + + L E+KEEE + R + Q E
Sbjct: 349 RDAKNLIEQLEQDKGMVIAETKRQMHETL--------EMKEEEIAQLRSRIKQMTTQGEE 400
Query: 571 TENPKQKIAAESSENVD-------CPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDF 623
K+K + E ++ E + KL ++D++ ++ +EE
Sbjct: 401 LREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE---------- 450
Query: 624 EDDTVQSSGPRAGGEELD---EGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQ 680
E ++Q R E +D + + AK+ + A + E + E E Q
Sbjct: 451 ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQ 510
Query: 681 DISDACEAESTERCEMSEHPSQTVRKALDSNSLE 714
+ A E +E ++S+ Q AL+ L+
Sbjct: 511 -MKVALEKSQSEYLKISQEKEQQESLALEELELQ 543
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 52.0 bits (123), Expect = 2e-06
Identities = 141/728 (19%), Positives = 271/728 (37%), Gaps = 105/728 (14%)
Query: 10 REIDCLSPEAQKLAEARLAAKR-------AARAEAREIRMKELERQQKEVEERPEKDFTE 62
RE+ E +L R+A +R AAR R R + L ++Q+E D E
Sbjct: 8 RELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVE 67
Query: 63 KGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKK----A 118
++N S+ ++ + +T + D EA+ E LA EE+ +K A
Sbjct: 68 VNAQN----------SVPDEEAKTTTTNTQVEGDDEAAFLE---RLARREERRQKRLQEA 114
Query: 119 MVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQF 178
+ + D T+ + + + E + E + E + + +E E+ +Q
Sbjct: 115 LERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174
Query: 179 AEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDG 238
+ ++A + ++E EK E G + V + T ++EE +
Sbjct: 175 NDWRDAEENKKEDKEKEEE--EEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKN-- 230
Query: 239 TLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSED 298
G+ S E K E G EI H+ + E+ ED K+ + E ++ +E
Sbjct: 231 --GQISSEEPKQEEEREQGSDEISHHEKMEE--ED--KERAEAERARLEAEERERIKAEQ 284
Query: 299 TAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDL 358
A EE+ +Q E E E E A ++R R E +
Sbjct: 285 DKKIADERARIEAEEKAAAQERERREAEERERMRE--EEKRAAEERQRIKEEEKRAAEER 342
Query: 359 DGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQ---ELETSTGHS 415
E +++E+ A ++K VE + +LE H+
Sbjct: 343 QRIKEEEKRAAEERQRIKEEEKRAAE---ERQRARAEEEEKAKVEEQKRNKQLEEKK-HA 398
Query: 416 LEKEFTNQEAAEPK-------EVPAHSTEVGRDHNEEEGEETG---------LRDEKPI- 458
+++ E E K E A ++ +++GEE G L+++KP
Sbjct: 399 MQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTF 458
Query: 459 -KTEVPGSPAGTEGNCQEAT--------GPSTVDTQN---------------------EP 488
K E+ + +E G + V +QN
Sbjct: 459 KKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRAS 518
Query: 489 LDMKEPDEEKSDQQGEALDSSQKK---TKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD 545
+D KE + + G+ L+ +++ T++++ + K+K L+++KK+ +
Sbjct: 519 VDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 578
Query: 546 LSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGD 605
L E ++ + + DRK E + + ++ AE++E + K+ DG D +
Sbjct: 579 LEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE-----KRQKMPEDGLSDDKKP 633
Query: 606 -DVQTAAEEVLADGDTLDFEDDTVQ-SSGPRAGGE-----ELDEGVAKDNAKIDGATQSS 658
T L + +F + +VQ SSG ++ + ++D + + + I+G +
Sbjct: 634 FKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAK 693
Query: 659 PAEPKSED 666
P +P + D
Sbjct: 694 PTKPAASD 701
Score = 40.4 bits (93), Expect = 0.006
Identities = 89/511 (17%), Positives = 186/511 (36%), Gaps = 59/511 (11%)
Query: 152 ESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSD 211
E RR+ + +E R + Q + +EA ++R + + E + G+ +D
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 212 TLN-NVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQH 270
+ N P + K + GD + + E ++ + E+++
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREER----RQKRLQEALERQKE 120
Query: 271 TEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTV 330
+ T+ D A + ++ DTA E ++ E S +
Sbjct: 121 FDPTITD--------ASLSLPSRRMQNDTA------------ENETTEKEEKSESRQERY 160
Query: 331 QVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHS 390
++E E T T N W D + + E EE+ +G +
Sbjct: 161 EIEETE--------TVTKSYQKNDWRDAEENKKEDKEKE------EEEEEKPKRGSIGEN 206
Query: 391 DDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET 450
V ++K + ET + +++E + +E S E+ EE ++
Sbjct: 207 QVEVMVEEKT---TESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263
Query: 451 GLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQ 510
E+ E + + A + ++ + + + E + ++ E + +
Sbjct: 264 RAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQER--ERREAEERERMREEE 321
Query: 511 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEV 570
K+ ++++ K+++ E + +K+E + IKEEE+ + +R+ A + E
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQR-IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 571 TENPKQKIAAESSENVDCPENPKI-------KLDGKLDQE----GDDVQTAAEEVLAD-- 617
+ +QK + E + KI K++GK E D +QTA + +
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK 440
Query: 618 GDTLDFEDDTVQSSGPRAGGEEL-DEGVAKD 647
G + + + +Q P EE+ DE + KD
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKD 471
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 51.6 bits (122), Expect = 3e-06
Identities = 129/577 (22%), Positives = 202/577 (35%), Gaps = 93/577 (16%)
Query: 192 LEKHGIILNSEIATNGETSDTLNNVGY-QGPTKMTK--EELNALKSTGDGTLGRASEVEV 248
LEK L+ ++ +T+ + +N G Q K T E++ A T T G E E
Sbjct: 251 LEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEK 310
Query: 249 KNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFP-------AGENT-----EDQKSS 296
+ V ++L T K + + P A EN E ++
Sbjct: 311 TEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENR 370
Query: 297 EDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWS 356
E TA TL+ A E + E+++ P E+ E M A ++ T P EP+
Sbjct: 371 ERTANENTTLSPAEPTENRERTANENTA-PFPAGPTENRE-MTANENTTLFPAEPTEHGE 428
Query: 357 DLDGGNHTENVGEAAV---TQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTG 413
N T + E E + P H + T + +DK + E
Sbjct: 429 RTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGER 488
Query: 414 HSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNC 473
L E T AEP E E T + P SPAG N
Sbjct: 489 TPLANENTTPSPAEP---------------TENRERTANENTTP-------SPAGPTENR 526
Query: 474 QEATGPSTVDTQNEPLDMKE--PDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVET 531
+ T + EP + +E +E+ + E ++ Q+ +K P T
Sbjct: 527 ETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEP----T 582
Query: 532 LKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPEN 591
+ L +NT S + E + T A + T +P AE +EN D
Sbjct: 583 EHGERTPLANENTTPSPAEPTENRERT-------ANEKTTPSP-----AEPTENGD---- 626
Query: 592 PKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKI 651
+ + + E +G F ++ SS E +A +N
Sbjct: 627 -------RTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANEN--- 676
Query: 652 DGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSN 711
T SPAEP +E+ +R T E+ +PS A TE EM+ + T+ A +
Sbjct: 677 ---TTPSPAEP-TENRER-TANENTTPS-------PAGPTENREMTANEKTTLFPAEPTE 724
Query: 712 SLE---NDDLSAPGREPGHFNPESREDTRGGNEKGKS 745
+ E N+ ++ EP E+ + T NEK S
Sbjct: 725 NRERTANEKTTSSPAEP----TENGQRTPFANEKTTS 757
Score = 38.9 bits (89), Expect = 0.018
Identities = 72/346 (20%), Positives = 117/346 (33%), Gaps = 39/346 (11%)
Query: 410 TSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTE-VPGSPAG 468
T + E T AEP E + E T + P+ E SPA
Sbjct: 542 TENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAE 601
Query: 469 TEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVP 528
N + T + EP + + +++ +L + + N+K S
Sbjct: 602 PTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSA 661
Query: 529 VETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEA------QNEVTENPKQKI-AAE 581
T + + L +NT S + E + T ++ + E+T N K + AE
Sbjct: 662 EPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAE 721
Query: 582 SSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDF--EDDTVQSSGPRAGGEE 639
+EN + N K ++ E +G F E T S+ P GE
Sbjct: 722 PTENRERTANEK-------------TTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGER 768
Query: 640 LDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEH 699
+A +N + A P E + A+ T P P+++ E T +
Sbjct: 769 TP--LANENTTLSPA---GPTENRERTANEKTTPFPAEPTEN------RERTANENTTPS 817
Query: 700 PSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKS 745
P+Q D L N+ + EP E+ + T NEK S
Sbjct: 818 PAQPTENG-DRTPLANEKTTPSLAEP----TENGKRTPFANEKTTS 858
Score = 32.0 bits (71), Expect = 2.2
Identities = 45/205 (21%), Positives = 68/205 (33%), Gaps = 27/205 (13%)
Query: 419 EFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTE-VPGSPAGTEGNCQEAT 477
E T AEP E + E T + P+ E SPAG N +
Sbjct: 732 EKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTA 791
Query: 478 GPSTVDTQNEPLDMKE--------PDEEKSDQQGEALDSSQKKT--------KNKKKK-- 519
T EP + +E P + + G+ + +KT +N K+
Sbjct: 792 NEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPF 851
Query: 520 -NKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQ-- 576
N+K S T + L +NT S + E + T + + E TEN +
Sbjct: 852 ANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTA 911
Query: 577 -----KIAAESSENVDCPENPKIKL 596
AE +EN + N L
Sbjct: 912 NEKTTPFPAEPTENREWTANENTTL 936
>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
sapiens]
Length = 788
Score = 51.6 bits (122), Expect = 3e-06
Identities = 101/466 (21%), Positives = 170/466 (36%), Gaps = 72/466 (15%)
Query: 297 EDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWS 356
++ A LG G T E ++ SL E + N V+G + E
Sbjct: 67 QEAASLLGKKYGETANECGEAFFFYGKSLLE--LARMENGVLGNALEGVHVEEEEGEKTE 124
Query: 357 DLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSL 416
D + +N+ E A ++ EQ +G ++ +DK + + + E + +
Sbjct: 125 DESLVENNDNIDEEAREELREQVYDA----MGEKEEAKKTEDKSLAKPETDKEQDS--EM 178
Query: 417 EKEFT-NQEAAEPKEVPAHSTEVGRDHNEEEGEET--GLRDEKPIKTEVP-GSPAGTEGN 472
EK + + ++ E P ++ D E EE G E P + EV G P +
Sbjct: 179 EKGGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPD 238
Query: 473 CQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKN-----KKKKSPV 527
+E S D Q E + + ++QGE + S ++K K ++ +K+ + V
Sbjct: 239 AEEEKSVSGTDVQEECRE-----KGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAV 293
Query: 528 PVE------TLKDV--------KKELTYQNTDLSEIKEE-------------EQVKSTDR 560
VE T+K V +K +T +N + E+ E
Sbjct: 294 EVEAESLDPTVKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTTEAAE 353
Query: 561 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKL-------DQEGDDVQTAAEE 613
SAVEA +EV+E P Q E P + DG + DQ + QT+ E
Sbjct: 354 ASAVEAGSEVSEKPGQ-------------EAPVLPKDGAVNGPSVVGDQTPIEPQTSIER 400
Query: 614 VLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGA-TQSSPAEPKSEDADRCTL 672
+ D E+ P EE V + A DG T+ + + D+ +
Sbjct: 401 LTETKDGSGLEEKVRAKLVP--SQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQI 458
Query: 673 PEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDL 718
+E + E E TE E + + + + + LEN L
Sbjct: 459 AANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLENKSL 504
Score = 32.7 bits (73), Expect = 1.3
Identities = 52/224 (23%), Positives = 84/224 (37%), Gaps = 28/224 (12%)
Query: 108 LAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFERE 167
LAE + A N+Q D F ++ +++ + L EQ+ E+ E KE E
Sbjct: 583 LAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEEL 642
Query: 168 KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKE 227
K E++E ++ +E + + AT E+S + G G +
Sbjct: 643 KEL-------LPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGG----SSV 691
Query: 228 ELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAG 287
+ A + DG AS +I V K+ E+E +D K A
Sbjct: 692 SMIASRKPTDG----ASSSNCVTDISHLVRKK---RKPEEESPRKDDAK--------KAK 736
Query: 288 ENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQ 331
+ E S D P G EE+ ++Q ES + E TV+
Sbjct: 737 QEPEVNGGSGDAVP-SGNEVSENMEEEAENQ-AESRAAVEGTVE 778
>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
sapiens]
Length = 790
Score = 51.6 bits (122), Expect = 3e-06
Identities = 101/466 (21%), Positives = 170/466 (36%), Gaps = 72/466 (15%)
Query: 297 EDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWS 356
++ A LG G T E ++ SL E + N V+G + E
Sbjct: 69 QEAASLLGKKYGETANECGEAFFFYGKSLLE--LARMENGVLGNALEGVHVEEEEGEKTE 126
Query: 357 DLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSL 416
D + +N+ E A ++ EQ +G ++ +DK + + + E + +
Sbjct: 127 DESLVENNDNIDEEAREELREQVYDA----MGEKEEAKKTEDKSLAKPETDKEQDS--EM 180
Query: 417 EKEFT-NQEAAEPKEVPAHSTEVGRDHNEEEGEET--GLRDEKPIKTEVP-GSPAGTEGN 472
EK + + ++ E P ++ D E EE G E P + EV G P +
Sbjct: 181 EKGGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPD 240
Query: 473 CQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKN-----KKKKSPV 527
+E S D Q E + + ++QGE + S ++K K ++ +K+ + V
Sbjct: 241 AEEEKSVSGTDVQEECRE-----KGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAV 295
Query: 528 PVE------TLKDV--------KKELTYQNTDLSEIKEE-------------EQVKSTDR 560
VE T+K V +K +T +N + E+ E
Sbjct: 296 EVEAESLDPTVKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTTEAAE 355
Query: 561 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKL-------DQEGDDVQTAAEE 613
SAVEA +EV+E P Q E P + DG + DQ + QT+ E
Sbjct: 356 ASAVEAGSEVSEKPGQ-------------EAPVLPKDGAVNGPSVVGDQTPIEPQTSIER 402
Query: 614 VLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGA-TQSSPAEPKSEDADRCTL 672
+ D E+ P EE V + A DG T+ + + D+ +
Sbjct: 403 LTETKDGSGLEEKVRAKLVP--SQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQI 460
Query: 673 PEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDL 718
+E + E E TE E + + + + + LEN L
Sbjct: 461 AANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLENKSL 506
Score = 32.7 bits (73), Expect = 1.3
Identities = 52/224 (23%), Positives = 84/224 (37%), Gaps = 28/224 (12%)
Query: 108 LAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFERE 167
LAE + A N+Q D F ++ +++ + L EQ+ E+ E KE E
Sbjct: 585 LAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEEL 644
Query: 168 KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKE 227
K E++E ++ +E + + AT E+S + G G +
Sbjct: 645 KEL-------LPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGG----SSV 693
Query: 228 ELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAG 287
+ A + DG AS +I V K+ E+E +D K A
Sbjct: 694 SMIASRKPTDG----ASSSNCVTDISHLVRKK---RKPEEESPRKDDAK--------KAK 738
Query: 288 ENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQ 331
+ E S D P G EE+ ++Q ES + E TV+
Sbjct: 739 QEPEVNGGSGDAVP-SGNEVSENMEEEAENQ-AESRAAVEGTVE 780
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 51.2 bits (121), Expect = 3e-06
Identities = 100/582 (17%), Positives = 207/582 (35%), Gaps = 91/582 (15%)
Query: 198 ILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVG 257
++ +E++ E SD + + E N + S D E NE V
Sbjct: 601 LVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSD---------EECNETVKEKQ 651
Query: 258 KREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQS 317
K + + ++++ D+ D P + +E + D+ L L + S
Sbjct: 652 KLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSS 711
Query: 318 QILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEE 377
+ + + N + + DD+ + + S SD D G++A + +
Sbjct: 712 SDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFD-----TKKGKSAKSSI-- 764
Query: 378 QAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTE 437
++ ++ +D + E+ + + +K N + + E HS +
Sbjct: 765 ----ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKK 820
Query: 438 VGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS---TVDTQNEPLDMKE- 493
G D+ + K +KT GS E + T S TVD +++++
Sbjct: 821 -GMDN----------QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDR 869
Query: 494 -PDEEKSDQQGEALDSSQKK--------------TKNKKKKNKKKKSPVPVETLKDVKKE 538
P ++++ + +D K TK K K K K + L D+ ++
Sbjct: 870 LPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEK 929
Query: 539 LTY--QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKI-- 594
Q+ + SE +++ K T+ K + +Q+ + S PE +I
Sbjct: 930 FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 989
Query: 595 --------------------KLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPR 634
K+ K ++ D++ AE+ GD+ D +D +G
Sbjct: 990 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNG-- 1047
Query: 635 AGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERC 694
A G E K K+ G + + S D ++ ++ E S D + +R
Sbjct: 1048 AYGRE------KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSD-------KRLKRI 1094
Query: 695 EMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDT 736
E+ E + + ++ ++ +++ S+ E N + ++ T
Sbjct: 1095 ELRERRNLSSKR--NTKEIQSGSSSSDAEESSEDNKKKKQRT 1134
Score = 48.5 bits (114), Expect = 2e-05
Identities = 109/601 (18%), Positives = 218/601 (36%), Gaps = 72/601 (11%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKG 64
A+A + +D LS + Q + + +++ ++ K ++ Q + + EK F +K
Sbjct: 876 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEK-FLKKD 934
Query: 65 SRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEK-----YKKAM 119
+ + G ++ S I E D ++ E+ + K +
Sbjct: 935 QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI 994
Query: 120 --VSNAQLDNEKTNFMYQVDTLK--DMLLELEEQLA------ESRRQYEEKNKEFEREKH 169
+ N D EK + + T K D L + E+ +S + KN + REK
Sbjct: 995 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1054
Query: 170 AHSILQFQFAEVKEALKQREEMLEKHGIILNS--------EIATNGETSDTLNNVGYQGP 221
+L + ++ E NS E+ S N Q
Sbjct: 1055 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSG 1114
Query: 222 TKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDI 281
+ + E +S+ D + K ++ KR L + K + + T DI
Sbjct: 1115 SSSSDAE----ESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1170
Query: 282 EVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAP 341
E +DQ S + + +EQ + E+ L +T +S+
Sbjct: 1171 E-------DDDQNS----------IGEGSSDEQKIKPVTENLVLSSHTGFCQSS------ 1207
Query: 342 DDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM 401
D + P D D + + + + +EE ++S G SDD K
Sbjct: 1208 GDEALSKSVPVTVDDDDDDNDPENRIAKKML--LEEIKANLSSDEDGSSDDEPEEGKKRT 1265
Query: 402 ----VEVPQELETSTGHSLEKEFTNQEAAEPK---EVPAHSTEVGRDHNEEEGEETGLRD 454
E P + E + E + ++E+ +P+ + H V + EE ++T ++
Sbjct: 1266 GKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEE-KKTKPKE 1324
Query: 455 EKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQK-KT 513
K +K N ++ + + D+ + + E E D+Q S++K +
Sbjct: 1325 HKEVKGR----------NRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1374
Query: 514 KNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTEN 573
+ ++ K+KK ++ +D E + + E KEEE+ + + + E +N+ +++
Sbjct: 1375 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKS 1434
Query: 574 P 574
P
Sbjct: 1435 P 1435
Score = 37.0 bits (84), Expect = 0.067
Identities = 68/339 (20%), Positives = 124/339 (36%), Gaps = 54/339 (15%)
Query: 429 KEVPAHST----EVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 484
KE+ + S+ E + N+++ + T + + I E + T ++A S+ +
Sbjct: 1109 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSS 1168
Query: 485 QNEPLDMKEPDEEKSDQQ-------GEALDSSQKKTKNKKKKNKKKKSPVPVET------ 531
E D E SD+Q L S ++ + K PV V+
Sbjct: 1169 DIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1228
Query: 532 ----------LKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAE 581
L+++K L+ S+ + EE K T +++ +N E K ++ +E
Sbjct: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE---ENPGDEEAKNQVNSE 1285
Query: 582 SSENVDCPENPKIK----------LDGKLDQEGDDVQTAAEEVLADG----DTLDFEDDT 627
S + + + P+ + DG+ +E +EV + D ED
Sbjct: 1286 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1345
Query: 628 VQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPK---SEDADRCTLPEHESPSQDISD 684
Q SG EE+ E + + A ++ E + + R + E S +
Sbjct: 1346 FQESGV---SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1402
Query: 685 ACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGR 723
E E E+ E E + + D ENDD +PG+
Sbjct: 1403 NSEEEEEEKEEEEEEEEEEEEEEED----ENDDSKSPGK 1437
Score = 36.6 bits (83), Expect = 0.088
Identities = 129/676 (19%), Positives = 244/676 (36%), Gaps = 109/676 (16%)
Query: 120 VSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFA 179
+S+A + F + +K L LEE L R + NK E+ H ++ +F
Sbjct: 345 ISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNK--EKNTKEHKVIDAKF- 401
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGT 239
E K ++ LEK I SE + + D+ ++ PT EE KSTG
Sbjct: 402 ETKARKGEKPCALEKKD-ISKSEAKLSRKQVDS-EHMHQNVPT----EEQRTNKSTG--- 452
Query: 240 LGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDT 299
G + + K E + E + +E +V V ++F EN E + +
Sbjct: 453 -GEHKKSDRKEE-----PQYEPANTSEDLDMDIVSVPSSVPEDIF---ENLETAMEVQSS 503
Query: 300 APFLGTLAGATYEEQVQSQILESSSLPENTVQVESNE---------VMGAPDDRTRTPLE 350
G + T +E S + + S +N ++S V P + +P++
Sbjct: 504 VDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIK 563
Query: 351 PSNCW---SDLDG------------------GNHTENVGEAAVTQVEEQAG-----TVAS 384
++C D DG + E++ E V+ + E++ V +
Sbjct: 564 GADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKT 623
Query: 385 CPLGHSDD----TVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAA----EPKEVPAHST 436
PL + T D++C V ++ + S + + + ++A +P ++P
Sbjct: 624 TPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQ 683
Query: 437 EVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDE 496
D N + E + K + S + T+ N + T ++ L +
Sbjct: 684 SETVDQNSDSDEMLAIL--KEVSRMSHSSSSDTDIN--------EIHTNHKTLYDLKTQA 733
Query: 497 EKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVK 556
K D+ SS + KK K KS + + + + E + +++L E+++K
Sbjct: 734 GKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSEL-----EKEIK 788
Query: 557 STDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLA 616
S + A + N K + D E+ K G +D +G ++E +
Sbjct: 789 SMSKIGAARTTKKRIPNTK---------DFDSSEDEKHSKKG-MDNQGHKNLKTSQEGSS 838
Query: 617 DGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKI----DGATQSSPAEPKSEDADRCTL 672
D E +T S+ EG + I D + A ++ D+ +
Sbjct: 839 DDAERKQERETFSSA----------EGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSG 888
Query: 673 PEHESPSQDISDACEAESTERCEMSEH-PSQTVRKALDSNSLENDDLSAPGREPGHFNPE 731
E S ++ E + E S+H ++T +K D S + + +
Sbjct: 889 KEQSFTSLEVRKVAETK-----EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD 943
Query: 732 SREDTRGGNEKGKSKE 747
++ +G EK K +
Sbjct: 944 KKQSKKGTEEKKKPSD 959
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 51.2 bits (121), Expect = 3e-06
Identities = 100/582 (17%), Positives = 207/582 (35%), Gaps = 91/582 (15%)
Query: 198 ILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVG 257
++ +E++ E SD + + E N + S D E NE V
Sbjct: 639 LVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSD---------EECNETVKEKQ 689
Query: 258 KREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQS 317
K + + ++++ D+ D P + +E + D+ L L + S
Sbjct: 690 KLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSS 749
Query: 318 QILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEE 377
+ + + N + + DD+ + + S SD D G++A + +
Sbjct: 750 SDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFD-----TKKGKSAKSSI-- 802
Query: 378 QAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTE 437
++ ++ +D + E+ + + +K N + + E HS +
Sbjct: 803 ----ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKK 858
Query: 438 VGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS---TVDTQNEPLDMKE- 493
G D+ + K +KT GS E + T S TVD +++++
Sbjct: 859 -GMDN----------QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDR 907
Query: 494 -PDEEKSDQQGEALDSSQKK--------------TKNKKKKNKKKKSPVPVETLKDVKKE 538
P ++++ + +D K TK K K K K + L D+ ++
Sbjct: 908 LPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEK 967
Query: 539 LTY--QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKI-- 594
Q+ + SE +++ K T+ K + +Q+ + S PE +I
Sbjct: 968 FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 1027
Query: 595 --------------------KLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPR 634
K+ K ++ D++ AE+ GD+ D +D +G
Sbjct: 1028 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNG-- 1085
Query: 635 AGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERC 694
A G E K K+ G + + S D ++ ++ E S D + +R
Sbjct: 1086 AYGRE------KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSD-------KRLKRI 1132
Query: 695 EMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDT 736
E+ E + + ++ ++ +++ S+ E N + ++ T
Sbjct: 1133 ELRERRNLSSKR--NTKEIQSGSSSSDAEESSEDNKKKKQRT 1172
Score = 48.5 bits (114), Expect = 2e-05
Identities = 109/601 (18%), Positives = 218/601 (36%), Gaps = 72/601 (11%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEVEERPEKDFTEKG 64
A+A + +D LS + Q + + +++ ++ K ++ Q + + EK F +K
Sbjct: 914 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEK-FLKKD 972
Query: 65 SRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEK-----YKKAM 119
+ + G ++ S I E D ++ E+ + K +
Sbjct: 973 QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI 1032
Query: 120 --VSNAQLDNEKTNFMYQVDTLK--DMLLELEEQLA------ESRRQYEEKNKEFEREKH 169
+ N D EK + + T K D L + E+ +S + KN + REK
Sbjct: 1033 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1092
Query: 170 AHSILQFQFAEVKEALKQREEMLEKHGIILNS--------EIATNGETSDTLNNVGYQGP 221
+L + ++ E NS E+ S N Q
Sbjct: 1093 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSG 1152
Query: 222 TKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDI 281
+ + E +S+ D + K ++ KR L + K + + T DI
Sbjct: 1153 SSSSDAE----ESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1208
Query: 282 EVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAP 341
E +DQ S + + +EQ + E+ L +T +S+
Sbjct: 1209 E-------DDDQNS----------IGEGSSDEQKIKPVTENLVLSSHTGFCQSS------ 1245
Query: 342 DDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM 401
D + P D D + + + + +EE ++S G SDD K
Sbjct: 1246 GDEALSKSVPVTVDDDDDDNDPENRIAKKML--LEEIKANLSSDEDGSSDDEPEEGKKRT 1303
Query: 402 ----VEVPQELETSTGHSLEKEFTNQEAAEPK---EVPAHSTEVGRDHNEEEGEETGLRD 454
E P + E + E + ++E+ +P+ + H V + EE ++T ++
Sbjct: 1304 GKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEE-KKTKPKE 1362
Query: 455 EKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQK-KT 513
K +K N ++ + + D+ + + E E D+Q S++K +
Sbjct: 1363 HKEVKGR----------NRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1412
Query: 514 KNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTEN 573
+ ++ K+KK ++ +D E + + E KEEE+ + + + E +N+ +++
Sbjct: 1413 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKS 1472
Query: 574 P 574
P
Sbjct: 1473 P 1473
Score = 37.0 bits (84), Expect = 0.067
Identities = 68/339 (20%), Positives = 124/339 (36%), Gaps = 54/339 (15%)
Query: 429 KEVPAHST----EVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 484
KE+ + S+ E + N+++ + T + + I E + T ++A S+ +
Sbjct: 1147 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSS 1206
Query: 485 QNEPLDMKEPDEEKSDQQ-------GEALDSSQKKTKNKKKKNKKKKSPVPVET------ 531
E D E SD+Q L S ++ + K PV V+
Sbjct: 1207 DIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1266
Query: 532 ----------LKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAE 581
L+++K L+ S+ + EE K T +++ +N E K ++ +E
Sbjct: 1267 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE---ENPGDEEAKNQVNSE 1323
Query: 582 SSENVDCPENPKIK----------LDGKLDQEGDDVQTAAEEVLADG----DTLDFEDDT 627
S + + + P+ + DG+ +E +EV + D ED
Sbjct: 1324 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1383
Query: 628 VQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPK---SEDADRCTLPEHESPSQDISD 684
Q SG EE+ E + + A ++ E + + R + E S +
Sbjct: 1384 FQESGV---SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1440
Query: 685 ACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGR 723
E E E+ E E + + D ENDD +PG+
Sbjct: 1441 NSEEEEEEKEEEEEEEEEEEEEEED----ENDDSKSPGK 1475
Score = 36.6 bits (83), Expect = 0.088
Identities = 129/676 (19%), Positives = 244/676 (36%), Gaps = 109/676 (16%)
Query: 120 VSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFA 179
+S+A + F + +K L LEE L R + NK E+ H ++ +F
Sbjct: 383 ISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNK--EKNTKEHKVIDAKF- 439
Query: 180 EVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGT 239
E K ++ LEK I SE + + D+ ++ PT EE KSTG
Sbjct: 440 ETKARKGEKPCALEKKD-ISKSEAKLSRKQVDS-EHMHQNVPT----EEQRTNKSTG--- 490
Query: 240 LGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDT 299
G + + K E + E + +E +V V ++F EN E + +
Sbjct: 491 -GEHKKSDRKEE-----PQYEPANTSEDLDMDIVSVPSSVPEDIF---ENLETAMEVQSS 541
Query: 300 APFLGTLAGATYEEQVQSQILESSSLPENTVQVESNE---------VMGAPDDRTRTPLE 350
G + T +E S + + S +N ++S V P + +P++
Sbjct: 542 VDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIK 601
Query: 351 PSNCW---SDLDG------------------GNHTENVGEAAVTQVEEQAG-----TVAS 384
++C D DG + E++ E V+ + E++ V +
Sbjct: 602 GADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKT 661
Query: 385 CPLGHSDD----TVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAA----EPKEVPAHST 436
PL + T D++C V ++ + S + + + ++A +P ++P
Sbjct: 662 TPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQ 721
Query: 437 EVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDE 496
D N + E + K + S + T+ N + T ++ L +
Sbjct: 722 SETVDQNSDSDEMLAIL--KEVSRMSHSSSSDTDIN--------EIHTNHKTLYDLKTQA 771
Query: 497 EKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVK 556
K D+ SS + KK K KS + + + + E + +++L E+++K
Sbjct: 772 GKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSEL-----EKEIK 826
Query: 557 STDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLA 616
S + A + N K + D E+ K G +D +G ++E +
Sbjct: 827 SMSKIGAARTTKKRIPNTK---------DFDSSEDEKHSKKG-MDNQGHKNLKTSQEGSS 876
Query: 617 DGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKI----DGATQSSPAEPKSEDADRCTL 672
D E +T S+ EG + I D + A ++ D+ +
Sbjct: 877 DDAERKQERETFSSA----------EGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSG 926
Query: 673 PEHESPSQDISDACEAESTERCEMSEH-PSQTVRKALDSNSLENDDLSAPGREPGHFNPE 731
E S ++ E + E S+H ++T +K D S + + +
Sbjct: 927 KEQSFTSLEVRKVAETK-----EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD 981
Query: 732 SREDTRGGNEKGKSKE 747
++ +G EK K +
Sbjct: 982 KKQSKKGTEEKKKPSD 997
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.122 0.326
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,993,507
Number of Sequences: 37866
Number of extensions: 1496524
Number of successful extensions: 12473
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 223
Number of HSP's successfully gapped in prelim test: 975
Number of HSP's that attempted gapping in prelim test: 7702
Number of HSP's gapped (non-prelim): 4088
length of query: 752
length of database: 18,247,518
effective HSP length: 110
effective length of query: 642
effective length of database: 14,082,258
effective search space: 9040809636
effective search space used: 9040809636
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.