BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21070997 stromal interaction molecule 1 precursor [Homo sapiens] (685 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21070997 stromal interaction molecule 1 precursor [Homo sapiens] 1377 0.0 gi|41349446 stromal interaction molecule 2 [Homo sapiens] 574 e-164 gi|148746195 trichohyalin [Homo sapiens] 54 4e-07 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 2e-06 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 52 2e-06 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 52 2e-06 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 52 2e-06 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 5e-06 gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 50 5e-06 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 7e-06 gi|115648142 centrosomal protein 164kDa [Homo sapiens] 50 7e-06 gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 50 7e-06 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 9e-06 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 49 2e-05 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 49 2e-05 gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 49 2e-05 gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 48 3e-05 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 48 3e-05 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 48 3e-05 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 47 4e-05 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 47 4e-05 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 47 6e-05 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 8e-05 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 46 1e-04 gi|226371725 FCH domain only 2 isoform b [Homo sapiens] 46 1e-04 gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 46 1e-04 gi|118498356 kinectin 1 isoform a [Homo sapiens] 46 1e-04 gi|118498368 kinectin 1 isoform c [Homo sapiens] 46 1e-04 gi|33620775 kinectin 1 isoform a [Homo sapiens] 46 1e-04 gi|22758136 MAP7 domain containing 2 [Homo sapiens] 46 1e-04 >gi|21070997 stromal interaction molecule 1 precursor [Homo sapiens] Length = 685 Score = 1377 bits (3563), Expect = 0.0 Identities = 685/685 (100%), Positives = 685/685 (100%) Query: 1 MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSED 60 MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSED Sbjct: 1 MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSED 60 Query: 61 EKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDL 120 EKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDL Sbjct: 61 EKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDL 120 Query: 121 WKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLK 180 WKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLK Sbjct: 121 WKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLK 180 Query: 181 MTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEH 240 MTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEH Sbjct: 181 MTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEH 240 Query: 241 MKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRL 300 MKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRL Sbjct: 241 MKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRL 300 Query: 301 KELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQ 360 KELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQ Sbjct: 301 KELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQ 360 Query: 361 YYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVT 420 YYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVT Sbjct: 361 YYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVT 420 Query: 421 AALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDM 480 AALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDM Sbjct: 421 AALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDM 480 Query: 481 DEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQM 540 DEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQM Sbjct: 481 DEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQM 540 Query: 541 SRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELS 600 SRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELS Sbjct: 541 SRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELS 600 Query: 601 PSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGS 660 PSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGS Sbjct: 601 PSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGS 660 Query: 661 IGEETDSSPGRKKFPLKIFKKPLKK 685 IGEETDSSPGRKKFPLKIFKKPLKK Sbjct: 661 IGEETDSSPGRKKFPLKIFKKPLKK 685 >gi|41349446 stromal interaction molecule 2 [Homo sapiens] Length = 833 Score = 574 bits (1480), Expect = e-164 Identities = 322/659 (48%), Positives = 405/659 (61%), Gaps = 77/659 (11%) Query: 25 HSHSEKATGTSSGANSEESTAA--------EFCRIDKPLCHSEDEKLSFEAVRNIHKLMD 76 H +ATG+++ A S + AA + C P C +E+++ S EA++ IHK MD Sbjct: 108 HLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMD 167 Query: 77 DDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDE 136 DD +G ++VEESDEF+RED+ Y D T KHS H EDK I++EDLWK WK+SEV+NWT+++ Sbjct: 168 DDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLED 227 Query: 137 VVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALD 196 +QWLI +VELPQYE+ FR + G +PR+AV + + LK++DRSHRQKLQLKALD Sbjct: 228 TLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALD 287 Query: 197 TVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQ 256 VLFGP HN +KDF+L VSIVIGVGGCWFAY QN+ SKEH+ KMMKDLE L AEQ Sbjct: 288 VVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQ 347 Query: 257 SLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKY 316 SL DLQERL KAQEE+R V VEK +LE+K+ DEIN AK+EA RL+ELREG E E SR++Y Sbjct: 348 SLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQY 407 Query: 317 AEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVA 376 AE+ELEQVR AL+KAEKE E SSW P+ALQKWLQLTHEVEVQYYNIK+QNAE QL +A Sbjct: 408 AEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIA 467 Query: 377 KEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEIL 436 K+ AEKIKKKR+T+FGT HVAHSSSLD+VDHKIL AK+ALSE+T LRERL RWQQIE + Sbjct: 468 KDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKI 527 Query: 437 CGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQ 496 CGFQI +N G+ SL ++L D SW+ R + + + VDD+DE+ +P + Sbjct: 528 CGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDED--------TPPIV 579 Query: 497 SSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGS 556 S + +P L L S R+ + P PQ RA Sbjct: 580 SQFPGTMAKPPGSLARSSSLCRS----------RRSIVPSSPQPQRA------------- 616 Query: 557 HRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGGSPHLDSSRS 616 + P +P PS P PH Sbjct: 617 -------------QLAPHAP-----------------------HPSHP--RHPHHPQHTP 638 Query: 617 HSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGSIGEETDSSPGRKKFP 675 HS SPDPD S + + + +K D S + +SS GRK+ P Sbjct: 639 HSLPSPDPDILSVSSCPALYRNEEEEEAIYFSAEKQWEVPDTASECDSLNSSIGRKQSP 697 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 54.3 bits (129), Expect = 4e-07 Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 5/109 (4%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E K+ ++LE +R E+ + +E+L + + E R + LE++ R+E L ++E Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR----RRQELERQYREEEELQQEEE 1181 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSW-YAPE 345 Q L+E +E ER RQ EEEL++ + R +++ S W + PE Sbjct: 1182 QLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230 Score = 50.8 bits (120), Expect = 4e-06 Identities = 36/137 (26%), Positives = 68/137 (49%), Gaps = 3/137 (2%) Query: 253 RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERS 312 R EQ L QE + Q+E R + E+ +++ R++ +QE +R ++LR E ER Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360 Query: 313 RQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEV---QYYNIKKQNA 369 Q+ E+ E+ RE + E++L + L++ QL E ++ Q ++Q Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420 Query: 370 EKQLLVAKEGAEKIKKK 386 +Q L ++ E+ ++K Sbjct: 421 REQQLRREQEEERHEQK 437 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/161 (20%), Positives = 77/161 (47%), Gaps = 5/161 (3%) Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291 ++ + +E ++ + E R EQ +++L + QEE R ++ + E++ ++ Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365 Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351 ++E +R ++LR + R +Q E++L RE + E++L + L++ Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRREQQLRREQQLRREQ 423 Query: 352 QLTHEVEVQYYNIKKQNAEKQLLVAKEGAEK---IKKKRNT 389 QL E E + + K + ++ + +E E+ +K++ T Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 7/156 (4%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E K+ ++ E +R E+ L +E+L + + E R + E++ R + L ++E Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR----RRQERERQYRKDKKLQQKEE 971 Query: 298 QRLKELREGTENERSRQKYAEEE-LEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 Q L E E + +KY EEE L+Q E L + E+E W + LQ E Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031 Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG 392 ++ K++ E++ +E E+++++ L G Sbjct: 1032 QLLREEREKRRLQERERQYREE--EELQQEEEQLLG 1065 Score = 49.3 bits (116), Expect = 1e-05 Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 11/136 (8%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E K+ +++ E +R E+ L +E+L + E R + LE++ R E L ++E Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETR----RRQELERQYRKEEELQQEEE 1091 Query: 298 QRLKELREGTEN-ERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 Q L+E E ER RQ EEEL+Q E L + E+E + L++ + E Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR------QELERQYREEEE 1145 Query: 357 VEVQYYNIKKQNAEKQ 372 V+ + + ++ EK+ Sbjct: 1146 VQQEEEQLLREEPEKR 1161 Score = 47.0 bits (110), Expect = 6e-05 Identities = 44/152 (28%), Positives = 72/152 (47%), Gaps = 24/152 (15%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E + ++LE +R E+ L +E+L + + E R + E++ R+E L ++E Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKR----RRQERERQCREEEELQQEEE 1121 Query: 298 QRLKELRE-GTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 Q L+E RE E RQ EEE++Q E L + E E E Sbjct: 1122 QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR----------------QE 1165 Query: 357 VEVQYYNIKK-QNAEKQLLVAKEGAEKIKKKR 387 +E QY ++ Q E+QLL +E EK +++R Sbjct: 1166 LERQYREEEELQQEEEQLL--REEQEKRRQER 1195 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/124 (25%), Positives = 63/124 (50%), Gaps = 3/124 (2%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ-E 296 +E ++K+ + + L R Q Q+RL + Q+ R E E+ +++ R++ +Q E Sbjct: 275 EEQLRKLER--QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332 Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 +R ++LR E R +Q E+E E+ + LR+ ++E + L++ QL E Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392 Query: 357 VEVQ 360 +++ Sbjct: 393 QQLR 396 Score = 44.3 bits (103), Expect = 4e-04 Identities = 36/157 (22%), Positives = 74/157 (47%), Gaps = 4/157 (2%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E +K ++ + + R E+ L+E QE HR E+ L+++ +++ +++ Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357 + L+E ++ ER R K+ E+EL + E+E + H + LQ+ QL + Sbjct: 1486 KFLEEEQQLRRQERDR-KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544 Query: 358 EVQYY---NIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391 Q +K E+QL +E + +++R+ F Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581 Score = 43.1 bits (100), Expect = 8e-04 Identities = 42/175 (24%), Positives = 79/175 (45%), Gaps = 23/175 (13%) Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQE--RLHKAQEEHRTVEVEKVHLEKKLRDE 289 ++ +E ++ ++ + R EQ L Q+ R + + E + +++ E++LR E Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410 Query: 290 INLAK-QEAQRLKELREGTENERSRQKYAEEELEQ-------VREALRKAEKELESHSSW 341 L + Q+ +R ++LR E ER QK+ +E EQ R K E+E E H Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470 Query: 342 YAPEAL---------QKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387 + L ++WL+L E + +++ E+QL +E + + KR Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERRE----QQERREQQLRREQEERREQRLKR 521 Score = 42.7 bits (99), Expect = 0.001 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 14/115 (12%) Query: 262 QERLHKAQEEH-----RTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKY 316 Q+RL + QEE + EVE++ E++ + + E +R ++L + E E RQ+ Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646 Query: 317 AEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEK 371 E ++ RE K E+E E L++ L+ HE E + + ++ E+ Sbjct: 647 LRREQQERREQRLKREEE---------EERLEQRLKREHEEERREQELAEEEQEQ 692 Score = 42.4 bits (98), Expect = 0.001 Identities = 38/155 (24%), Positives = 78/155 (50%), Gaps = 8/155 (5%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTV-EVEKVHLEKKLRDEINLAKQE 296 +E +K M+D + L R E QER K +E+ + + E E+ L ++ RD L ++ Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650 Query: 297 AQRLKELREGTENERSRQKYAEEEL--EQVREALRKAEKE---LESHSSWYAPEALQKWL 351 R +E + ++R R+ EE+L E + LR+ E++ E E +K+L Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710 Query: 352 QLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 Q E +++ ++++ E++ L + E+++++ Sbjct: 1711 Q--EEQQLRRQELERKFREEEQLRQETEQEQLRRQ 1743 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/161 (25%), Positives = 71/161 (44%), Gaps = 31/161 (19%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQER--------LHKAQEEHRTVEVEKVHLEKKLRDE 289 +E +++ ++ +GL ++ ++R L + ++ R K L+++LR E Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE 902 Query: 290 INLAKQEAQRLK--ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEAL 347 L ++E + L+ E + E+ RQ EE+L+Q E L + E+E Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR--------- 953 Query: 348 QKWLQLTHEVEVQYYNIKK-QNAEKQLLVAKEGAEKIKKKR 387 E E QY KK Q E+QLL G E K++R Sbjct: 954 -------QERERQYRKDKKLQQKEEQLL----GEEPEKRRR 983 Score = 39.7 bits (91), Expect = 0.009 Identities = 41/157 (26%), Positives = 74/157 (47%), Gaps = 6/157 (3%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q R + ++ + + L R E++ QER + Q+ R E E+ KL +E Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQER--RKQQLKRDQEEERRERWLKLEEEERR 497 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 +QE + + RE E R K EEE E++++ LR +E++L + L++ + Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEE-ERLQQRLR-SEQQLRREQEERREQLLKREEE 555 Query: 353 LTHEVEVQYYNIKKQNAEK--QLLVAKEGAEKIKKKR 387 E E + +K++ E+ QLL +E + + KR Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592 Score = 38.1 bits (87), Expect = 0.027 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 14/138 (10%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKK-LRDEIN 291 Q+R +E +K + E + R E+ LQE + Q E + E + LE++ LR E Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEE--KLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291 Query: 292 LAKQEAQRLK-----------ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS 340 +Q+ QRL+ E RE E R +Q+ E++ E+ + LR+ ++E Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351 Query: 341 WYAPEALQKWLQLTHEVE 358 E ++ QL E E Sbjct: 352 RREQEEERREQQLRREQE 369 Score = 37.7 bits (86), Expect = 0.036 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 6/135 (4%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 K H + D E L R E L +L+ + + +++ R ++V E+ +E K+E Sbjct: 197 KGHETEEFPDEEQLRRRE--LLELRRKGREEKQQQRRERQDRVFQEE---EEKEWRKRET 251 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357 KE + E E RQ+ +EE EQ+R+ L + E E + L++ QL + Sbjct: 252 VLRKEEEKLQEEEPQRQRELQEEEEQLRK-LERQELRRERQEEEQQQQRLRREQQLRRKQ 310 Query: 358 EVQYYNIKKQNAEKQ 372 E + +++ E+Q Sbjct: 311 EEERREQQEERREQQ 325 Score = 37.7 bits (86), Expect = 0.036 Identities = 46/211 (21%), Positives = 89/211 (42%), Gaps = 36/211 (17%) Query: 235 RYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAK 294 R +E +++ +K E ++ + + + + +EE R ++ E++ + ++ + Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651 Query: 295 QE--AQRLK----------ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY 342 QE QRLK L+ E ER Q+ AEEE EQ RE ++ Sbjct: 652 QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK------------- 698 Query: 343 APEALQKW-LQLTHEVEVQ----YYNIKKQNAEKQLLVAKEGAEKIKKKRNTL-FGTFHV 396 + KW QL E + + Y +KQ +++ +E EK +++ + L + Sbjct: 699 --SRIPKWQWQLESEADARQSKVYSRPRKQEGQRR---RQEQEEKRRRRESELQWQEEER 753 Query: 397 AHSSSLDDVDHKILTAKQALSEVTAALRERL 427 AH ++ + T + E + R+RL Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784 Score = 37.7 bits (86), Expect = 0.036 Identities = 38/178 (21%), Positives = 80/178 (44%), Gaps = 23/178 (12%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDL--QERLHKAQEEHRTVEVEKVHLEKKLRDEI 290 + ++ +E + ++LE R E+ L QE+L + + + +E E++ E R+E Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE---REEQ 1762 Query: 291 NLAKQEAQRL----KELREGTENERSRQKYA------EEELEQVREALRKAEKELESHSS 340 L +QE R ++LR+ E ++ R + + EE+L Q RE + ++ + Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822 Query: 341 W--------YAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 W + L++ + E Q+ +K E+Q L +E ++ +++ L Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880 Score = 37.0 bits (84), Expect = 0.061 Identities = 47/177 (26%), Positives = 79/177 (44%), Gaps = 22/177 (12%) Query: 236 YSKEHMKKMMKDLEGLH-RAEQSLHDLQERLHKAQEEHRTVE-----------VEKVHLE 283 Y K + + LE R QS DLQ L + QE R E E+ LE Sbjct: 1241 YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLE 1300 Query: 284 KKLRDEINLAKQEAQRLKEL-REGTENERSRQ----KYAEEE---LEQVREALRKAEKEL 335 ++ + E +++Q K+L RE E +R RQ K+ EEE E+ + LR+ E++ Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360 Query: 336 E-SHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391 + E +K+L+ + Q +K E+Q L +E +++++ R+ F Sbjct: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERE-RKFLKEEQQLRCQEREQQLRQDRDRKF 1416 Score = 35.8 bits (81), Expect = 0.14 Identities = 39/159 (24%), Positives = 71/159 (44%), Gaps = 9/159 (5%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q R + + + E L R EQ + + R K+QEE + + E+ EK+ R E + Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQK--EAKRRDRKSQEEKQLLREERE--EKRRRQETDR 1336 Query: 293 AKQEAQRLKELREGTENERSRQ--KYAEEELEQVREALRKAEKELESHSSWYAPEALQKW 350 +E ++L + RE R + K+ EEEL + + E+E + L++ Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396 Query: 351 LQL---THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 QL E +++ +K E+Q L +E K +++ Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREE 1435 Score = 35.8 bits (81), Expect = 0.14 Identities = 33/155 (21%), Positives = 73/155 (47%), Gaps = 8/155 (5%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E +K +K+ + L E+ Q+R K +EE + ++ + ++K R+E +++ Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ--QLSRQERDRKFREEEQQVRRQE 1443 Query: 298 QRLKELREGTE--NERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355 + K L E + ER R+ EE+L Q RE + +E + E Q+ + Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL----EEEQQLRRQER 1499 Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 + + + ++ Q E++ L ++ + +++R L Sbjct: 1500 DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534 Score = 35.4 bits (80), Expect = 0.18 Identities = 40/167 (23%), Positives = 78/167 (46%), Gaps = 13/167 (7%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q R ++ K+ ++ E + E+ H Q+ +E+ R + EK R L Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQE----EEQRRDFTWQWQAEEKSERGRQRL 784 Query: 293 AKQ---EAQRLKELREGTENERSRQKYA--EEELEQVREALRKAEKELESHSSWYAPEAL 347 + + QR ++LR E ++ Q++ EEE EQ R R+ EKEL+ + Sbjct: 785 SARPPLREQRERQLR-AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843 Query: 348 QKWLQLTHEVEVQYYNIKKQNAEKQLLVAK---EGAEKIKKKRNTLF 391 ++ QL E + + +++ +++Q K + E+ K++R+TL+ Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY 890 Score = 35.0 bits (79), Expect = 0.23 Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 14/162 (8%) Query: 235 RYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAK 294 R+ +E K+ +K + R E+ L L+E + Q+E R ++ + E++ R E L + Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLK-LEEEERREQQERREQQLRR---EQEERREQRLKR 521 Query: 295 QEA-QRL-------KELREGTENERSRQKYAEEE--LEQVREALRKAEKELESHSSWYAP 344 QE +RL ++LR E R + EEE LEQ R R ++ E Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581 Query: 345 EALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 E ++ +L E E + K+ ++L + +++K++ Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623 Score = 35.0 bits (79), Expect = 0.23 Identities = 37/172 (21%), Positives = 77/172 (44%), Gaps = 18/172 (10%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q R ++ ++ + E + ++ LQ+RL Q+ R E + L K+ ++ Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559 Query: 293 AKQEAQRLKELRE-------GTENERSRQKYAEEELEQVREALRKAEKE-------LESH 338 ++ QRLK +E E ER +Q+ E+ E++ + L++ E E E Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619 Query: 339 SSWYAP--EALQKWLQLTHEVEVQYYNIKKQNAEK--QLLVAKEGAEKIKKK 386 P E Q+ L+ + E + ++++ E+ Q L +E E+++++ Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671 Score = 34.3 bits (77), Expect = 0.39 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 12/131 (9%) Query: 249 EGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLK----ELR 304 E L R Q + +ER +A+EE ++ K H ++ DE L ++E L+ E + Sbjct: 171 EELWRQRQEWQEREER--RAEEEQ--LQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226 Query: 305 EGTENERSRQKYAEEELEQVRE---ALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQY 361 + ER + + EEE ++ R+ LRK E++L+ E LQ+ + ++E Q Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE-LQEEEEQLRKLERQE 285 Query: 362 YNIKKQNAEKQ 372 ++Q E+Q Sbjct: 286 LRRERQEEEQQ 296 Score = 34.3 bits (77), Expect = 0.39 Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 8/134 (5%) Query: 255 EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKEL-REGTENERSR 313 EQ L + +E+ + QE R E+ L ++ R+ L +++ R +EL R+ E E+ R Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732 Query: 314 QKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL-QLTHEVEVQYYNIKKQNAEKQ 372 Q+ +E+L + +E RK +E + PE ++ L + + + + +Q E+Q Sbjct: 1733 QETEQEQLRR-QERYRKILEEEQ-----LRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786 Query: 373 LLVAKEGAEKIKKK 386 L ++E K +++ Sbjct: 1787 QLRSQESDRKFREE 1800 Score = 33.9 bits (76), Expect = 0.51 Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 5/99 (5%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQS---LHDLQERLHKAQEEHRTVEVEKVHLEKKLRDE 289 Q R +E + + +G +R E+ L + ++RL + ++ E + EK R+E Sbjct: 1802 QLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861 Query: 290 INLAKQEAQRLKELREG--TENERSRQKYAEEELEQVRE 326 L ++E Q+ ++ RE E RQ+ E+ QV E Sbjct: 1862 QELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900 Score = 33.5 bits (75), Expect = 0.67 Identities = 34/149 (22%), Positives = 66/149 (44%), Gaps = 14/149 (9%) Query: 249 EGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTE 308 +G +Q + Q+R+ + +EE + E V ++E L ++E QR +EL+E E Sbjct: 221 KGREEKQQQRRERQDRVFQEEEEKEWRKRETV----LRKEEEKLQEEEPQRQRELQEEEE 276 Query: 309 NERS-------RQKYAEEELEQ---VREALRKAEKELESHSSWYAPEALQKWLQLTHEVE 358 R R++ EE+ +Q + LR+ ++E E ++ Q E Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336 Query: 359 VQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387 Q +++ E+QL +E + ++ R Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLR 365 Score = 33.1 bits (74), Expect = 0.88 Identities = 32/155 (20%), Positives = 69/155 (44%), Gaps = 6/155 (3%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 + K+ ++ E EQS + QERL + + R E+ + E + R+E +++ Sbjct: 136 RRRQKRQEQERELAEGEEQS--EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL 193 Query: 298 QRLK--ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355 Q K E E + E+ R++ E + RE K ++ E + E ++W + Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGRE--EKQQQRRERQDRVFQEEEEKEWRKRET 251 Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 + + ++++ ++Q + +E + K +R L Sbjct: 252 VLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286 Score = 33.1 bits (74), Expect = 0.88 Identities = 33/157 (21%), Positives = 72/157 (45%), Gaps = 28/157 (17%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 + ++ K+L+ L EQ +ER + QEE ++ D+ QE Sbjct: 821 RRQRREREKELQFLEEEEQLQR--RERAQQLQEEEDGLQ----------EDQERRRSQEQ 868 Query: 298 QRLKELREGTENERSRQKYA-------EEELEQVREALRKAEKELESHSSWYAPEALQKW 350 +R ++ R E ER R+++ +E+L + ++ L++ E+EL+ ++ Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE---------ERE 919 Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387 + E E QY ++ E++ L+ +E ++ +++R Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956 Score = 32.0 bits (71), Expect = 2.0 Identities = 30/155 (19%), Positives = 72/155 (46%), Gaps = 11/155 (7%) Query: 242 KKMMKDLEGLHRAEQSLHDLQERLH--KAQEEHRTVEVEKVHLEK----KLRDEINLAKQ 295 ++ ++ + L R +Q + +E H K ++E R +++ E+ K +E +Q Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469 Query: 296 EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ--- 352 E ++ + R+ E R R EE E+ RE + E++L + L++ + Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEE--EERREQQERREQQLRREQEERREQRLKRQEEEER 527 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387 L + + ++Q ++ L+ +E ++++++R Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562 Score = 31.6 bits (70), Expect = 2.5 Identities = 37/159 (23%), Positives = 71/159 (44%), Gaps = 19/159 (11%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q S+E +K +++ EQ LH Q + QEE + E+ ++ RD Sbjct: 1506 QELRSQEPERKFLEE-------EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 +++ ++ +E ++ + ER R+ EE+ + +E RK +E E Q Q Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKF---MEDEQQLRRQEGQQ---Q 1612 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391 L E + +K ++QLL +E + +++R+ F Sbjct: 1613 LRQERD------RKFREDEQLLQEREEQQLHRQERDRKF 1645 Score = 29.6 bits (65), Expect = 9.7 Identities = 39/136 (28%), Positives = 63/136 (46%), Gaps = 25/136 (18%) Query: 262 QERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEEL 321 Q R K QE+ R + + EK+ R L +++ QR E E R RQ++ E Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQER----LEQRDRQRRDE-----ELWRQRQEWQE--- 182 Query: 322 EQVREALRKAEKELES---HSSWYAPEALQ----KWLQLTHEVEVQYYNIKKQNAEKQLL 374 RE R E++L+S H + P+ Q + L+L + + ++Q E+Q Sbjct: 183 ---REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK---QQQRRERQDR 236 Query: 375 VAKEGAEKIKKKRNTL 390 V +E EK +KR T+ Sbjct: 237 VFQEEEEKEWRKRETV 252 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 52.0 bits (123), Expect = 2e-06 Identities = 39/208 (18%), Positives = 92/208 (44%), Gaps = 11/208 (5%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKA----------QEEHRTVEVEKVHLEKKLR 287 +E +M + E + EQ + D +ER+ K QEE E EKK+R Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599 Query: 288 DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREAL-RKAEKELESHSSWYAPEA 346 +E + +++ ++++E E + + + EE++++ E + + EK E + + Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659 Query: 347 LQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVD 406 L + + E E K Q E+++ ++ +K +++ + + S+ + + Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719 Query: 407 HKILTAKQALSEVTAALRERLHRWQQIE 434 K+ ++ + E ++E+ + Q+ E Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQE 747 Score = 43.9 bits (102), Expect = 5e-04 Identities = 43/209 (20%), Positives = 93/209 (44%), Gaps = 15/209 (7%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E KK+ K E + R E ERL + + + R E + EK+LR++ Sbjct: 277 QEEELREQEKKIRKQEEKMWRQE-------ERLREQEGKMREQEEKMWRQEKRLREQEKE 329 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSWYAPEALQKW 350 +++ + L+E +E E E Q+ E+ EQ E +R+ E+++ + W + +++ Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQ-EEKMREQEEKMWRQEERLWEQEKQMREQ 388 Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAK-----EGAEKIKKKRNTLFGTFHVAHSSSLDDV 405 Q + E + + ++ EK+ + + E EK+++++ Sbjct: 389 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE 448 Query: 406 DHKILTAKQALSEVTAALRERLHRWQQIE 434 + +I ++ + E +RE+ + Q+ E Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQE 477 Score = 43.9 bits (102), Expect = 5e-04 Identities = 40/148 (27%), Positives = 70/148 (47%), Gaps = 8/148 (5%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298 E K+M + + + E+ + + ERL + +E R E +EK +R+E + +QE + Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK-MREEKKMQEQEKK 438 Query: 299 RLKELREGTENE--RSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 + + E E R R+K EE E +RE K +K+ E + W E + +L + Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE--NMWEQEEKEWQQQRLPEQ 496 Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIK 384 E + K Q E+++ E EKI+ Sbjct: 497 KEKLWEQEKMQEQEEKIW---EQEEKIR 521 Score = 42.4 bits (98), Expect = 0.001 Identities = 47/201 (23%), Positives = 92/201 (45%), Gaps = 21/201 (10%) Query: 238 KEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296 K ++ +K+L+ L RA+ L +Q + QEE E E EKK+R + ++ Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQVQT--NTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298 Query: 297 AQRLKELREGTENERSRQKYAEEE-LEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355 +RL+E +EG E+ + + +E+ L + + LR+ EKEL E ++ Q+ Sbjct: 299 EERLRE-QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK-----ELREQEEQMQE 352 Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGA--EKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAK 413 + E + +K +++ + +E E+ K+ R + D + ++ Sbjct: 353 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE---------QEQKMRDQEERMWEQD 403 Query: 414 QALSEVTAALRERLHRWQQIE 434 + L E +RE+ W+Q+E Sbjct: 404 ERLREKEERMREQEKMWEQVE 424 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/162 (19%), Positives = 79/162 (48%), Gaps = 12/162 (7%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQE-EHRTVEVEKVH-------LEKKLRDEI 290 EH K M++ E + E+ + + ++ K QE E +T + EK+ EKK+R+E Sbjct: 669 EHEK--MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726 Query: 291 NLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKW 350 + +++ ++++E E + + EE++ + E + + ++ E + E +Q+ Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 786 Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG 392 ++ + E +K +++ + +E EK++ + ++G Sbjct: 787 EKIWEQEEKMRDQEEKMRGQEEKMRGQE--EKMRGQEEKMWG 826 Score = 38.1 bits (87), Expect = 0.027 Identities = 31/146 (21%), Positives = 68/146 (46%), Gaps = 3/146 (2%) Query: 235 RYSKEHMKKMMKDLEGLHRA-EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293 R +E M++ K E + + E+ QE+ + QEE E EKK+R+E Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466 Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEALQKWLQ 352 +++ +++++ E E+ +++ ++ L + +E L + EK E W E ++ + Sbjct: 467 REQEEKMQKQEENMW-EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKE 378 + + + + K + E Q+ +E Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEE 551 Score = 37.4 bits (85), Expect = 0.046 Identities = 25/115 (21%), Positives = 58/115 (50%), Gaps = 3/115 (2%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E KKM ++ E + E+ + + +E++ + +EE E + E+K+ ++ L +Q+ Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK- 774 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 ++L E + E E+ ++ EE++ E +R E+++ + + W Q Sbjct: 775 EKLWEHEKMQEQEKIWEQ--EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQ 827 Score = 34.7 bits (78), Expect = 0.30 Identities = 37/200 (18%), Positives = 92/200 (46%), Gaps = 13/200 (6%) Query: 242 KKMMKDLEGLHRAEQSLHD---LQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298 KKM + + E+ + + ++ER K +EE T+ ++ EK + E N+ +QE Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQE---EKMQKQEENMWEQEE- 485 Query: 299 RLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVE 358 KE ++ E+ + + +E++++ E + + E+++ + E + E E Sbjct: 486 --KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543 Query: 359 VQYY--NIKKQNAEKQLLVAKEGAEK--IKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQ 414 Q + K ++ E+++ +E EK ++++ T + + + + K+ ++ Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603 Query: 415 ALSEVTAALRERLHRWQQIE 434 + E ++E+ + Q+ E Sbjct: 604 MMREQEEKMQEQEEKMQEQE 623 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 52.0 bits (123), Expect = 2e-06 Identities = 41/173 (23%), Positives = 81/173 (46%), Gaps = 3/173 (1%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q + +E +K+ + E + R E+ + +L+E + +E+ R VE + E+K++++ Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY-APEALQKWL 351 +++ ++++E E T + K E+ EQ + R+ EK E E +Q+ Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530 Query: 352 QLTHEVEVQYY--NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSL 402 + E EV+ + K Q E +L +E K+ +K L G + S L Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583 Score = 43.5 bits (101), Expect = 6e-04 Identities = 39/202 (19%), Positives = 95/202 (47%), Gaps = 23/202 (11%) Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRDEINL 292 N +++ +KM + E + E+ + + QE + QEE + EK+H E+K+R++ + Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCE-QELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 ++ ++++E E + + EE++ + E +++ E+E+ W E +++ + Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM-----WRQEEKIREQEE 402 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTA 412 E K EK++ +E EKI+++ ++ + +++ + Sbjct: 403 KRQE--------KMWRQEKKM---REQDEKIREQEEEMW-----RQEEKIRELEEMMQDQ 446 Query: 413 KQALSEVTAALRERLHRWQQIE 434 ++ L EV ++E + Q+ E Sbjct: 447 EEKLREVEEKMQEEEEKMQEQE 468 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/169 (17%), Positives = 83/169 (49%), Gaps = 18/169 (10%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQER-----------LHKAQEEHRTVEVEKVH 281 Q +E +K+ + E + R E+ + + +E+ + + E+ R E E Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431 Query: 282 LEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSW 341 E+K+R+ + + + ++L+E+ E + E + + EE++++ E +++ E++ +W Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK-----TW 486 Query: 342 YAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 + L++ ++ + E + +K +++ + +E EK++++ + Sbjct: 487 RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKM--QEQEEKMQRQEEKM 533 Score = 40.0 bits (92), Expect = 0.007 Identities = 27/153 (17%), Positives = 75/153 (49%), Gaps = 2/153 (1%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + + E+ + +E++H+ +E+ R E + E+K+R++ Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 +++ +++ E + + + EEE+ + E +R+ E E W + +++ + Sbjct: 362 IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE-EKRQEKMWRQEKKMREQDE 420 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKK 385 E E + + +++ E + ++ ++ EK+++ Sbjct: 421 KIREQEEEMWRQEEKIRELEEMM-QDQEEKLRE 452 Score = 39.3 bits (90), Expect = 0.012 Identities = 42/209 (20%), Positives = 97/209 (46%), Gaps = 20/209 (9%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + E + ++ + + +E + + +E+ R E E+ EK R E + Sbjct: 358 QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR--EQEEKRQEKMWRQEKKM 415 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQV----REALRKAEKEL--ESHSSWYAPEA 346 +Q+ +++RE E E RQ+ ELE++ E LR+ E+++ E E Sbjct: 416 REQD----EKIRE-QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470 Query: 347 LQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVD 406 +Q+ + E E + + +K +++ + +E EK+ ++ ++ + + + Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE--EKMWRQEEKMW-----EQEEKMQEQE 523 Query: 407 HKILTAKQALSEVTAALRERLHRWQQIEI 435 K+ ++ + E L ++ + Q+ E+ Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEV 552 Score = 30.8 bits (68), Expect = 4.3 Identities = 37/200 (18%), Positives = 92/200 (46%), Gaps = 21/200 (10%) Query: 240 HMKKMMKDLEG----LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ 295 +++K+ K+ + L+R + +L+E+ + QE+ R VE EK ++ ++D K+ Sbjct: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKD----LKR 246 Query: 296 EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355 + +R + L ++ Q A+ ++++ K + ++E + W Q+ Sbjct: 247 KLERAQLLLP----QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302 Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQA 415 E ++Q +++ +Q L +E EK+ ++ + + + + K+ ++ Sbjct: 303 EEKIQE---QEEKMCEQELKIREQEEKMWRQEEKMH-----EQEEKIREQEDKMWRQEEK 354 Query: 416 LSEVTAALRERLHR-WQQIE 434 + E +RE+ + W+Q E Sbjct: 355 IREQEEKIREQEEKMWRQEE 374 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 52.0 bits (123), Expect = 2e-06 Identities = 41/173 (23%), Positives = 81/173 (46%), Gaps = 3/173 (1%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q + +E +K+ + E + R E+ + +L+E + +E+ R VE + E+K++++ Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY-APEALQKWL 351 +++ ++++E E T + K E+ EQ + R+ EK E E +Q+ Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530 Query: 352 QLTHEVEVQYY--NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSL 402 + E EV+ + K Q E +L +E K+ +K L G + S L Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583 Score = 43.5 bits (101), Expect = 6e-04 Identities = 39/202 (19%), Positives = 95/202 (47%), Gaps = 23/202 (11%) Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRDEINL 292 N +++ +KM + E + E+ + + QE + QEE + EK+H E+K+R++ + Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCE-QELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 ++ ++++E E + + EE++ + E +++ E+E+ W E +++ + Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM-----WRQEEKIREQEE 402 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTA 412 E K EK++ +E EKI+++ ++ + +++ + Sbjct: 403 KRQE--------KMWRQEKKM---REQDEKIREQEEEMW-----RQEEKIRELEEMMQDQ 446 Query: 413 KQALSEVTAALRERLHRWQQIE 434 ++ L EV ++E + Q+ E Sbjct: 447 EEKLREVEEKMQEEEEKMQEQE 468 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/169 (17%), Positives = 83/169 (49%), Gaps = 18/169 (10%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQER-----------LHKAQEEHRTVEVEKVH 281 Q +E +K+ + E + R E+ + + +E+ + + E+ R E E Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431 Query: 282 LEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSW 341 E+K+R+ + + + ++L+E+ E + E + + EE++++ E +++ E++ +W Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK-----TW 486 Query: 342 YAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 + L++ ++ + E + +K +++ + +E EK++++ + Sbjct: 487 RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKM--QEQEEKMQRQEEKM 533 Score = 40.0 bits (92), Expect = 0.007 Identities = 27/153 (17%), Positives = 75/153 (49%), Gaps = 2/153 (1%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + + E+ + +E++H+ +E+ R E + E+K+R++ Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 +++ +++ E + + + EEE+ + E +R+ E E W + +++ + Sbjct: 362 IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE-EKRQEKMWRQEKKMREQDE 420 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKK 385 E E + + +++ E + ++ ++ EK+++ Sbjct: 421 KIREQEEEMWRQEEKIRELEEMM-QDQEEKLRE 452 Score = 39.3 bits (90), Expect = 0.012 Identities = 42/209 (20%), Positives = 97/209 (46%), Gaps = 20/209 (9%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + E + ++ + + +E + + +E+ R E E+ EK R E + Sbjct: 358 QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR--EQEEKRQEKMWRQEKKM 415 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQV----REALRKAEKEL--ESHSSWYAPEA 346 +Q+ +++RE E E RQ+ ELE++ E LR+ E+++ E E Sbjct: 416 REQD----EKIRE-QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470 Query: 347 LQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVD 406 +Q+ + E E + + +K +++ + +E EK+ ++ ++ + + + Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE--EKMWRQEEKMW-----EQEEKMQEQE 523 Query: 407 HKILTAKQALSEVTAALRERLHRWQQIEI 435 K+ ++ + E L ++ + Q+ E+ Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEV 552 Score = 30.8 bits (68), Expect = 4.3 Identities = 37/200 (18%), Positives = 92/200 (46%), Gaps = 21/200 (10%) Query: 240 HMKKMMKDLEGL----HRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ 295 +++K+ K+ + L +R + +L+E+ + QE+ R VE EK ++ ++D K+ Sbjct: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKD----LKR 246 Query: 296 EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTH 355 + +R + L ++ Q A+ ++++ K + ++E + W Q+ Sbjct: 247 KLERAQLLLP----QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302 Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQA 415 E ++Q +++ +Q L +E EK+ ++ + + + + K+ ++ Sbjct: 303 EEKIQE---QEEKMCEQELKIREQEEKMWRQEEKMH-----EQEEKIREQEDKMWRQEEK 354 Query: 416 LSEVTAALRERLHR-WQQIE 434 + E +RE+ + W+Q E Sbjct: 355 IREQEEKIREQEEKMWRQEE 374 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 10/144 (6%) Query: 254 AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKK--LRDEINLAKQEAQRLKELREGTENER 311 AE+ +E A+E R E EK E++ +++E A +E QR+KE + ER Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370 Query: 312 SRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEK 371 R + EEE +V E R + E + H+ E K ++ ++E ++ N KK +K Sbjct: 371 QRARAEEEEKAKVEEQKRNKQLEEKKHA---MQETKIKGEKVEQKIEGKWVNEKKAQEDK 427 Query: 372 --QLLVAKEGAE---KIKKKRNTL 390 ++ K+G E K++ KR L Sbjct: 428 LQTAVLKKQGEEKGTKVQAKREKL 451 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/165 (21%), Positives = 71/165 (43%), Gaps = 23/165 (13%) Query: 240 HMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLE---------------- 283 H +KM ++ + AE++ + +ER E+ + + E+ +E Sbjct: 253 HHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAE 312 Query: 284 --KKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSW 341 +++R+E A +E QR+KE + ER R K E+ + R+ +++ EK Sbjct: 313 ERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 372 Query: 342 YAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 E +K +VE Q N + + + + K EK+++K Sbjct: 373 ARAEEEEK-----AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQK 412 Score = 30.0 bits (66), Expect = 7.4 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 12/97 (12%) Query: 237 SKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296 S+E K K E E+ +ER +EE + + E+ ++KLR+E +E Sbjct: 548 SEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA--DRKLREE-----EE 600 Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEK 333 +RLKE E ER R + AE+ + + L +K Sbjct: 601 KRRLKE-----EIERRRAEAAEKRQKMPEDGLSDDKK 632 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 50.4 bits (119), Expect = 5e-06 Identities = 28/159 (17%), Positives = 84/159 (52%), Gaps = 6/159 (3%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q ++ +KM + E +H E+ + + +E++ + +E+ R E + E+K+R++ + Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 +++ +++ E E + + + EE++ + E +R+ EK++ E +++ + Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE-----EKIREQEE 662 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391 + E E + + +++ E++ + +E EK++++ ++ Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKM-QEQEEKMRRQEEKMW 700 Score = 45.4 bits (106), Expect = 2e-04 Identities = 37/157 (23%), Positives = 81/157 (51%), Gaps = 13/157 (8%) Query: 233 QNRYSKEHMKKMMKDLEG---LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDE 289 + R +E +++ K E + R E+ + + +E++ + QEE + EK+H ++K+R+E Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-QEEKMWRQEEKIHEQEKIREE 516 Query: 290 INLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQK 349 +QE +E + + E RQK E++ + E +RK E+++ W E + Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQK---EKIHEQEEKIRKQEEKM-----WRQEEKMHD 568 Query: 350 WLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 + E E + + +++ E++ + +E EKI+++ Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKI-REQEEKIREQ 604 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/137 (20%), Positives = 70/137 (51%), Gaps = 4/137 (2%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV-HLEKKLRDEINLAKQEA 297 +H+ K ++ + +A+ ++L RL++ QEE + EK+ E+K++++ +++ Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSWYAPEALQKWLQLTH 355 ++++E E + EE++ + E + + E+++ + W E +++ + H Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448 Query: 356 EVE-VQYYNIKKQNAEK 371 E E ++ K+Q EK Sbjct: 449 EQEKIREQEEKRQEEEK 465 Score = 44.7 bits (104), Expect = 3e-04 Identities = 42/210 (20%), Positives = 103/210 (49%), Gaps = 21/210 (10%) Query: 233 QNRYSKEHM---KKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRD 288 + R +E M ++ +++ E + R ++ +H+ +E++ K QEE + EK+H E+K+R+ Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK-QEEKMWRQEEKMHDQEEKIRE 575 Query: 289 EINLAKQEAQRLKE----LREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAP 344 + ++ ++++E +RE E R +++ +E+ E++ E + EK E Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE---QEEKMCEQEEKMQEQ 632 Query: 345 EALQKWLQLTHEVEVQYYNIKKQNAE--KQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSL 402 E +K + ++ Q I++Q + +Q + +E EK+ ++ + + Sbjct: 633 E--EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM-----CEQEEKM 685 Query: 403 DDVDHKILTAKQALSEVTAALRERLHRWQQ 432 + + K+ ++ + E LR++ + Q+ Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715 Score = 43.1 bits (100), Expect = 8e-04 Identities = 45/220 (20%), Positives = 101/220 (45%), Gaps = 26/220 (11%) Query: 235 RYSKEHMKK----MMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRDE 289 R +E M++ M + E + R E+ + + +E++ + QEE + EK+ LE+K+ ++ Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR-QEEMMWEKEEKIRELEEKMHEQ 450 Query: 290 INLAKQEAQRLKELREGTENERSRQK----YAEEELEQVREALRKAEKELESHSSWYAPE 345 + +QE +R +E + + +R Q+ EE++ + E +R+ E+++ W E Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM-----WRQEE 505 Query: 346 ALQKWLQLTHEVEVQYYNIKKQNAEK---------QLLVAKEGAEKIKKKRNTLFGTFHV 396 + + ++ E + Q + EK Q E EKI+K+ ++ Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565 Query: 397 AH--SSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIE 434 H + + + K+ ++ + E +RE+ + ++ E Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/143 (21%), Positives = 72/143 (50%), Gaps = 5/143 (3%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E +K+ + E + E+ + +E + + +E+ R E E+K+R + + ++ Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437 Query: 298 QRLKELREGT-ENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEALQKWLQLTH 355 ++++EL E E E+ R+ +EE Q E +R+ EK E + W E +++ + Sbjct: 438 EKIRELEEKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494 Query: 356 EVEVQYYNIKKQNAEKQLLVAKE 378 E E + + +++ E++ + +E Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEE 517 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/113 (19%), Positives = 59/113 (52%), Gaps = 7/113 (6%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q ++E +KM + E + E+ + + +E++ + +E+ R E + E+K+R++ + Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVRE-------ALRKAEKELESH 338 +++ +++ E E + + + EE++ + E LR+ E++++ H Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 716 Score = 36.2 bits (82), Expect = 0.10 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 11/157 (7%) Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293 +RY +E K+ L+R + +L+E+ K QE+ + VE EK EI L Sbjct: 253 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--------SEIQLN 304 Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353 +E +R E + ++ Q A+ ++++ K + ++E + W Q+ Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 364 Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 E ++Q + K Q E+++ +E EKI+++ + Sbjct: 365 RQEEKIQEWEEKIQEQEEKI---REQEEKIREQEEKM 398 Score = 36.2 bits (82), Expect = 0.10 Identities = 18/99 (18%), Positives = 50/99 (50%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + E + E+ + + +E++ + +E + E + E+K+ ++ Sbjct: 625 QEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 684 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKA 331 +++ ++++ E + R + EE++++ +E L A Sbjct: 685 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 723 >gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo sapiens] Length = 482 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/107 (33%), Positives = 63/107 (58%), Gaps = 7/107 (6%) Query: 242 KKMMKDLEGLHRAEQSLHD---LQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298 ++ +++ + L R Q LH+ L+E+ KAQEE R ++ EK KK ++E +E Sbjct: 55 EQQLEEEKLLERERQRLHEEWLLREQ--KAQEEFR-IKKEKEEAAKKRQEEQERKLKEQW 111 Query: 299 RLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPE 345 ++ +E E E+ RQ+ E+E E +++ L +AE ELE+ ++W PE Sbjct: 112 EEQQRKEREEEEQKRQEKKEKE-EALQKMLDQAENELENGTTWQNPE 157 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 50.1 bits (118), Expect = 7e-06 Identities = 32/141 (22%), Positives = 72/141 (51%), Gaps = 5/141 (3%) Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293 NR +++ +KM + E + E+ + + +E++ + +E+ R E E+K+R + + Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 339 Query: 294 KQEAQRLKELREGT-ENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEALQKWL 351 ++ ++++EL E E E+ R+ +EE Q E +R+ EK E + W E +++ Sbjct: 340 WEKEEKIRELEEKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 396 Query: 352 QLTHEVEVQYYNIKKQNAEKQ 372 + E E +++ E++ Sbjct: 397 EKIREQEEMMQEQEEKMGEQE 417 Score = 46.2 bits (108), Expect = 1e-04 Identities = 27/158 (17%), Positives = 82/158 (51%), Gaps = 6/158 (3%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + E + E+ + + +E++ + +E+ R E + E+K+R++ + Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ 352 +++ +++ E + ++ + EE++ + E +R+ EK++ E +++ + Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE-----EKIREQEE 516 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 + E E + + +++ E++ + +E EK++++ + Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKM-QEQEEKMRRQEEKM 553 Score = 45.1 bits (105), Expect = 2e-04 Identities = 41/220 (18%), Positives = 99/220 (45%), Gaps = 34/220 (15%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLH----------KAQEEHRTVEVEKVH------- 281 E +KM + E + E+ + +L+E++H K QEE + E EK Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386 Query: 282 -LEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS 340 E+K+R++ +++ + ++E E + + EEE+++ E +R+ E+++ Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446 Query: 341 WY--APEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAH 398 E +++ ++ E E + + + E++ + +E EK++++ Sbjct: 447 KIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM-QEQEEKMRRQ------------ 493 Query: 399 SSSLDDVDHKILTAKQALSEVTAALRERLHR-WQQIEILC 437 + + + KI ++ + E ++E+ + W+Q E +C Sbjct: 494 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533 Score = 40.0 bits (92), Expect = 0.007 Identities = 29/154 (18%), Positives = 77/154 (50%), Gaps = 5/154 (3%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV-HLEKKLRDEINLAKQEA 297 +H+ K ++ + +A+ ++L RL++ QEE + EK+ E+K++++ +++ Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQE 315 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL-ESHSSWYAPEALQKWLQLTHE 356 ++++ E + + + EE + + E +R+ E+++ E E Q+ ++ + Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375 Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 + Q K E+++ +E EKI+++ + Sbjct: 376 EKRQEQEAKMWRQEEKI---REQEEKIREQEEMM 406 Score = 38.5 bits (88), Expect = 0.021 Identities = 20/103 (19%), Positives = 52/103 (50%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + + E + + +E++ + +E+ R E + E+K+R++ + Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL 335 +++ +++ E E + + + EE++ + E +R+ E L Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560 Score = 34.3 bits (77), Expect = 0.39 Identities = 35/158 (22%), Positives = 72/158 (45%), Gaps = 11/158 (6%) Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293 +RY +E K+ L+R + +L+E+ K QE+ + VE EK EI L Sbjct: 180 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--------SEIQLN 231 Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353 +E +R E + ++ Q A+ ++++ K + ++E + W Q+ Sbjct: 232 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 291 Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391 E ++Q K Q E+++ +E EK++++ ++ Sbjct: 292 RQEEKIQEREEKIQEQEEKI---REQEEKMRRQEEMMW 326 Score = 33.9 bits (76), Expect = 0.51 Identities = 15/91 (16%), Positives = 46/91 (50%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + E + E+ + + +E++ + +E + E + E+K+ ++ Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQ 323 +++ ++++ E + R + EE++++ Sbjct: 539 MQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569 >gi|115648142 centrosomal protein 164kDa [Homo sapiens] Length = 1460 Score = 50.1 bits (118), Expect = 7e-06 Identities = 49/188 (26%), Positives = 88/188 (46%), Gaps = 33/188 (17%) Query: 255 EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENE---- 310 EQSL L+ERL KA EE +E + ++E+QRL LR ++ Sbjct: 641 EQSLSSLRERLQKAIEE----------------EEARMREEESQRLSWLRAQVQSSTQAD 684 Query: 311 ----RSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKK 366 R+ Q+ + ++L + E+ +KAE+ + E L++ ++ + + E N K Sbjct: 685 EDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK 744 Query: 367 QNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRER 426 + A +QL E+++ +R T HS+ L+ + L AK EV ++L+++ Sbjct: 745 EKALQQL------REQLEGERKEAVATLEKEHSAELERLCSS-LEAKH--REVVSSLQKK 795 Query: 427 LHRWQQIE 434 + QQ E Sbjct: 796 IQEAQQKE 803 Score = 31.6 bits (70), Expect = 2.5 Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 12/161 (7%) Query: 234 NRYSKEHMKKMMKDLEGLHRAEQS-----LHDLQERLHKAQEEH-RTVEVEKVHLEKKLR 287 ++ +EH + M K E E+ L L L + Q H R +E + K+L Sbjct: 852 DKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLE 911 Query: 288 DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK----ELESHSSWYA 343 D +++ ++L++L E R++ A L +V+E + EK +++ + + Sbjct: 912 DLRRRHREQERKLQDLELDLET-RAKDVKARLALLEVQEETARREKQQLLDVQRQVALKS 970 Query: 344 PEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIK 384 EA QL E + ++ ++ + N + + ++ + A K+K Sbjct: 971 EEATATHQQL-EEAQKEHTHLLQSNQQLREILDELQARKLK 1010 >gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] Length = 898 Score = 50.1 bits (118), Expect = 7e-06 Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 13/186 (6%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 KE ++M + + A Q + + + ++E + EK LEKKLRD ++ Sbjct: 288 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNT 347 Query: 298 QRLKELREGTENERSRQKYAEEELEQVR--EALRKAEKELESHSSWYAPEALQKWLQLTH 355 ++K+L + E R Q Y +E E R + K ++++ SH KW Q Sbjct: 348 NKIKQLSQ--EKGRLHQLYETKEGETTRLIREIDKLKEDINSH------VIKVKWAQNKL 399 Query: 356 EVEVQYYNIKKQNAEK---QLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTA 412 + E+ + K ++ +L AKE A++I+K + T+ + +++D K+ Sbjct: 400 KAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVT 459 Query: 413 KQALSE 418 K L + Sbjct: 460 KGELEK 465 Score = 34.7 bits (78), Expect = 0.30 Identities = 53/255 (20%), Positives = 113/255 (44%), Gaps = 29/255 (11%) Query: 253 RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKE---------- 302 R E L +E +++ + E + + ++KV +L++++ KQE + LKE Sbjct: 514 RTEDELSKYKEIINRQKAEIQNL-LDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLIN 572 Query: 303 -LREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQY 361 L++ E R R E EL E L +L+S S+ + K +++ Q Sbjct: 573 DLQKDIEGSRKR----ESELLLFTERLTSKNAQLQSESNSLQSQ-FDKVSCSESQLQSQC 627 Query: 362 YNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG------TFHVAHSSSLDDVDHKILTAKQ- 414 +K+ N + + KE E K++ TL T A S+ ++++ +++T ++ Sbjct: 628 EQMKQTNINLESRLLKE-EELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 686 Query: 415 ---ALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVA-ALNIDPSWMGSTRPNPAH 470 ++ ++T L++ + Q+E + V++ G S + +LN S + N Sbjct: 687 HASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARSSAEDRSPENTGS 746 Query: 471 FIMTDDVDDMDEEIV 485 + D+ +D+ ++ Sbjct: 747 SVAVDNFPQVDKAML 761 Score = 30.0 bits (66), Expect = 7.4 Identities = 35/188 (18%), Positives = 84/188 (44%), Gaps = 27/188 (14%) Query: 237 SKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296 +KE ++ K+ + + + Q ++ K+ E + V K LEK+++++ + + Sbjct: 423 AKEEADQIRKNCQDMIKTYQESEEI-----KSNELDAKLRVTKGELEKQMQEKSDQLEMH 477 Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 ++KEL E+ + K +EL +R ++ E E + L K+ ++ + Sbjct: 478 HAKIKEL----EDLKRTFKEGMDELRTLRTKVKCLEDE-----RLRTEDELSKYKEIINR 528 Query: 357 VEVQYYNI-----KKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILT 411 + + N+ ++QL K+ E +K++ +L +S ++D+ I Sbjct: 529 QKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESL--------NSLINDLQKDIEG 580 Query: 412 AKQALSEV 419 +++ SE+ Sbjct: 581 SRKRESEL 588 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 49.7 bits (117), Expect = 9e-06 Identities = 36/167 (21%), Positives = 80/167 (47%), Gaps = 13/167 (7%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q + ++ +KM + E L E + + +E++ + ++ R E E EK+LR++ L Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKL 305 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL---------ESHSSWYA 343 +QE Q ++E E + + + EE++ + E L + EK++ + W Sbjct: 306 REQEEQ-MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364 Query: 344 PEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 E L++ + E E + +K E+++ +E +K++++ T+ Sbjct: 365 DERLREKEERMREQEKMWEQEEKMQEEERI---REREKKMREEEETM 408 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/208 (19%), Positives = 95/208 (45%), Gaps = 22/208 (10%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQ----EEHRTVEVEKVH-LEKKLR 287 Q + +E +KM E + ++ L + +ER+ + + +E + E E++ EKK+R Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402 Query: 288 DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEA 346 +E +++ +++++ E E+ +++ ++ L + +E L + EK E W E Sbjct: 403 EEEETMREQEEKMQKQEENMW-EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461 Query: 347 LQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVD 406 ++ ++ + + + K + E Q+ E EK++ + ++ D + Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMW---EQEEKMRDQEQKMW------------DQE 506 Query: 407 HKILTAKQALSEVTAALRERLHRWQQIE 434 ++ + L E +RE+ WQQ E Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEE 534 Score = 43.9 bits (102), Expect = 5e-04 Identities = 35/152 (23%), Positives = 77/152 (50%), Gaps = 6/152 (3%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E ++M + E + E+ + + +E++ + +E E + E+K+RD+ ++ Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365 Query: 298 QRLKELREGTENERSRQK-YAEEELEQVREALRKAEKEL--ESHSSWYAPEALQKWLQLT 354 +RL RE E R ++K + +EE Q E +R+ EK++ E + E +QK + Sbjct: 366 ERL---REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422 Query: 355 HEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 E E + + ++ +K+ L +E ++ ++K Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/129 (17%), Positives = 62/129 (48%), Gaps = 9/129 (6%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV---------HLE 283 Q +E +KM + E + E+ + + +E++ + +EE + E E++ E Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645 Query: 284 KKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYA 343 +K+ ++ +++ ++++E E + + + + EE+++ E +R+ E+++ Sbjct: 646 EKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMW 705 Query: 344 PEALQKWLQ 352 + + W Q Sbjct: 706 GQEEKMWGQ 714 Score = 41.2 bits (95), Expect = 0.003 Identities = 46/224 (20%), Positives = 89/224 (39%), Gaps = 36/224 (16%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQS--------LHDLQERLHKA------------QEEH 272 +N + E +KK +L+ R +S + +L+ +L +A QEE Sbjct: 177 RNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 236 Query: 273 RTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAE 332 E E EKK+R + ++ +RL+E + + + E+ L + + LR+ E Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296 Query: 333 KELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGA--EKIKKKRNTL 390 KEL E Q+ + E + +K +++ + +E E+ K+ R Sbjct: 297 KELREQKKLREQEE-----QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE-- 349 Query: 391 FGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIE 434 + D + ++ + L E +RE+ W+Q E Sbjct: 350 -------QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE 386 Score = 41.2 bits (95), Expect = 0.003 Identities = 33/165 (20%), Positives = 79/165 (47%), Gaps = 12/165 (7%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKA-----QEEHRTVEVEKVHLEKKLR 287 Q ++ +KM E + ++ L + +ER+ + QEE E + EKK Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550 Query: 288 DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEAL 347 D+ ++E +R++E + E + EE++++ E +R+ E+++ W E + Sbjct: 551 DQEEKMREE-ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM-----WEQEEKM 604 Query: 348 QKWLQLTHEVEVQYYNIKKQN-AEKQLLVAKEGAEKIKKKRNTLF 391 Q+ + E E + + ++++ ++Q + E EK++++ ++ Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649 Score = 40.8 bits (94), Expect = 0.004 Identities = 43/198 (21%), Positives = 93/198 (46%), Gaps = 17/198 (8%) Query: 242 KKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL-RDEINLAKQEAQRL 300 ++M + E L E+ + +E++ + +E R E + E+K+ R E L +QE Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE---- 289 Query: 301 KELREGTENERSRQKY--AEEELEQVREALRKAEKEL--ESHSSWYAPEALQKWLQLTHE 356 KELRE + R ++K EE++++ E + + E+++ + W E L W Q E Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL--WEQ---E 344 Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQAL 416 +++ K ++ E+++ E E++++K + + + +I ++ + Sbjct: 345 KQMREQEQKMRDQEERMW---EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKM 401 Query: 417 SEVTAALRERLHRWQQIE 434 E +RE+ + Q+ E Sbjct: 402 REEEETMREQEEKMQKQE 419 Score = 38.9 bits (89), Expect = 0.016 Identities = 45/210 (21%), Positives = 92/210 (43%), Gaps = 19/210 (9%) Query: 235 RYSKEHMK--KMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 R +E M+ K M E R E+ + QE+ QEE E EKK+R+E + Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQE-QEKKTWDQEEKMREEERMREREKKMREEEEM 575 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK---ELESHSSWYAPEALQK 349 +++ ++++E E + + EE++++ E + + E+ E E E + Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM- 634 Query: 350 WLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKI 409 W Q E ++Q K E+++ +E EK++++ + G + + + K+ Sbjct: 635 WEQ---EEKMQEQEEKMWEQEEKM---REQEEKMREQEEKMQG-----QEEKMREQEEKM 683 Query: 410 LTAKQALSEVTAALRERLHR-WQQIEILCG 438 ++ + E +R + + W Q E + G Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWG 713 Score = 35.0 bits (79), Expect = 0.23 Identities = 20/119 (16%), Positives = 56/119 (47%), Gaps = 9/119 (7%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 + + +E KM + E + E+ + + +E++ + +E+ R E+K+R++ Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-------EQEEKMREQEEK 668 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSWYAPEALQK 349 + + ++++E E + + + + EE++ E + E+++ + W E +K Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK 727 Score = 35.0 bits (79), Expect = 0.23 Identities = 20/110 (18%), Positives = 53/110 (48%), Gaps = 10/110 (9%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298 E +KM + E + E+ + + +E++ + +E+ + E + E+K++ + +++ + Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695 Query: 299 RLKELRE----------GTENERSRQKYAEEELEQVREALRKAEKELESH 338 +++ E G E + Q+ E+ E++R+ K ++ L H Sbjct: 696 KMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745 Score = 33.5 bits (75), Expect = 0.67 Identities = 43/216 (19%), Positives = 98/216 (45%), Gaps = 24/216 (11%) Query: 235 RYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV--HLEKKLRD---- 288 R +E M+K +++ E L E+ K E+ + E E+ E+K+RD Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468 Query: 289 ---EINLAKQEAQRLKELREGTENERSRQKYA-----EEELEQVREALRKAEKEL-ESHS 339 E + +QE R +E + + E+ R + EE + + E LR+ E+ + E Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKK 528 Query: 340 SWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHS 399 W E +++ + T E E + ++ +++ E++ + +E +K++++ + Sbjct: 529 MWQQEEKMRE-EKKTQEQEKKTWDQEEKMREEERM--REREKKMREEEEMM-----REQE 580 Query: 400 SSLDDVDHKILTAKQALSEVTAALRERLHR-WQQIE 434 + + + K+ ++ + E ++E+ + W+Q E Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 616 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 48.9 bits (115), Expect = 2e-05 Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 18/181 (9%) Query: 237 SKEHMKKMMKDLEGLHR--------AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRD 288 S E KK+ DLE R A++S+ D++ + E+ + E E +L+ K+ D Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102 Query: 289 EINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ 348 E L Q +++KEL ++R + EEE+E R + KAEK+ S S E + Sbjct: 1103 EQALGIQLQKKIKEL-------QARIEELEEEIEAERASRAKAEKQ-RSDLSRELEEISE 1154 Query: 349 KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHK 408 + + Q KK+ AE Q + + E+ + T H+ S+ ++ + Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQKM--RRDLEEATLQHEATAATLRKKHADSVAELGEQ 1212 Query: 409 I 409 I Sbjct: 1213 I 1213 Score = 38.1 bits (87), Expect = 0.027 Identities = 43/203 (21%), Positives = 91/203 (44%), Gaps = 23/203 (11%) Query: 239 EHMKKMMKDLEGLHRA-EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 E + K+ K+ + L A +Q+L DLQ +++ T+ K+ LE+++ D +QE Sbjct: 993 ETIAKLTKEKKALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1048 Query: 298 QRLKELREGTENERSRQKYAEE-------ELEQVREALRKAEKELESHSSWYAPEALQKW 350 + +L K A+E E +Q+ E L+K E E+ + S E + Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE---QA 1105 Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKIL 410 L + + +++ + + E+++ + K +K+R+ L S L+++ ++ Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL--------SRELEEISERLE 1157 Query: 411 TAKQALSEVTAALRERLHRWQQI 433 A A S ++R +Q++ Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKM 1180 Score = 35.0 bits (79), Expect = 0.23 Identities = 27/143 (18%), Positives = 67/143 (46%), Gaps = 7/143 (4%) Query: 233 QNRYSKEHMKKMMKDLEGLH-RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291 + + +++ ++D + L + ++ + +LQ R+ + +EE + EK+ D Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147 Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351 ++ ++RL+E T + K E E +++R L +A + E+ ++ + Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVA 1207 Query: 352 QLTHEVEVQYYNIK--KQNAEKQ 372 +L +++ N++ KQ EK+ Sbjct: 1208 ELGEQID----NLQRVKQKLEKE 1226 Score = 35.0 bits (79), Expect = 0.23 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 11/113 (9%) Query: 274 TVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK 333 T ++E+ L+++L +EI A L+ R + R + + +E +++ AL KA Sbjct: 1315 TQQIEE--LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANT 1372 Query: 334 ELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 E+ + Y +A+Q+ T E+E KK+ A++ L A+E E + K Sbjct: 1373 EVAQWRTKYETDAIQR----TEELE----EAKKKLAQR-LQAAEEHVEAVNAK 1416 Score = 34.3 bits (77), Expect = 0.39 Identities = 43/180 (23%), Positives = 78/180 (43%), Gaps = 38/180 (21%) Query: 237 SKEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHRTVEV----EKVHLEKKLRDEIN 291 S+ ++ K +EG L+ E L+ +A +R + ++HL+ LR + + Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672 Query: 292 LAKQEAQ----------RLKELREGTENERSRQKYAEEELEQVRE----------ALRKA 331 L +Q A ++ELR E +K AE+EL E +L Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732 Query: 332 EKELESHSSWYAPEALQKWLQLTHEVE--VQYYNIKKQNAEKQLLVAKEGAEKIKKKRNT 389 +K+LE+ S Q+ E+E +Q ++ A+K + A AE++KK+++T Sbjct: 1733 KKKLETDIS-----------QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDT 1781 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 48.9 bits (115), Expect = 2e-05 Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 18/181 (9%) Query: 237 SKEHMKKMMKDLEGLHR--------AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRD 288 S E KK+ DLE R A++S+ D++ + E+ + E E +L+ K+ D Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102 Query: 289 EINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ 348 E L Q +++KEL ++R + EEE+E R + KAEK+ S S E + Sbjct: 1103 EQALGIQLQKKIKEL-------QARIEELEEEIEAERASRAKAEKQ-RSDLSRELEEISE 1154 Query: 349 KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHK 408 + + Q KK+ AE Q + + E+ + T H+ S+ ++ + Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQKM--RRDLEEATLQHEATAATLRKKHADSVAELGEQ 1212 Query: 409 I 409 I Sbjct: 1213 I 1213 Score = 38.1 bits (87), Expect = 0.027 Identities = 43/203 (21%), Positives = 91/203 (44%), Gaps = 23/203 (11%) Query: 239 EHMKKMMKDLEGLHRA-EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 E + K+ K+ + L A +Q+L DLQ +++ T+ K+ LE+++ D +QE Sbjct: 993 ETIAKLTKEKKALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1048 Query: 298 QRLKELREGTENERSRQKYAEE-------ELEQVREALRKAEKELESHSSWYAPEALQKW 350 + +L K A+E E +Q+ E L+K E E+ + S E + Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE---QA 1105 Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKIL 410 L + + +++ + + E+++ + K +K+R+ L S L+++ ++ Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL--------SRELEEISERLE 1157 Query: 411 TAKQALSEVTAALRERLHRWQQI 433 A A S ++R +Q++ Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKM 1180 Score = 35.0 bits (79), Expect = 0.23 Identities = 27/143 (18%), Positives = 67/143 (46%), Gaps = 7/143 (4%) Query: 233 QNRYSKEHMKKMMKDLEGLH-RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291 + + +++ ++D + L + ++ + +LQ R+ + +EE + EK+ D Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147 Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351 ++ ++RL+E T + K E E +++R L +A + E+ ++ + Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVA 1207 Query: 352 QLTHEVEVQYYNIK--KQNAEKQ 372 +L +++ N++ KQ EK+ Sbjct: 1208 ELGEQID----NLQRVKQKLEKE 1226 Score = 35.0 bits (79), Expect = 0.23 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 11/113 (9%) Query: 274 TVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK 333 T ++E+ L+++L +EI A L+ R + R + + +E +++ AL KA Sbjct: 1315 TQQIEE--LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANT 1372 Query: 334 ELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 E+ + Y +A+Q+ T E+E KK+ A++ L A+E E + K Sbjct: 1373 EVAQWRTKYETDAIQR----TEELE----EAKKKLAQR-LQAAEEHVEAVNAK 1416 Score = 34.3 bits (77), Expect = 0.39 Identities = 43/180 (23%), Positives = 78/180 (43%), Gaps = 38/180 (21%) Query: 237 SKEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHRTVEV----EKVHLEKKLRDEIN 291 S+ ++ K +EG L+ E L+ +A +R + ++HL+ LR + + Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672 Query: 292 LAKQEAQ----------RLKELREGTENERSRQKYAEEELEQVRE----------ALRKA 331 L +Q A ++ELR E +K AE+EL E +L Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732 Query: 332 EKELESHSSWYAPEALQKWLQLTHEVE--VQYYNIKKQNAEKQLLVAKEGAEKIKKKRNT 389 +K+LE+ S Q+ E+E +Q ++ A+K + A AE++KK+++T Sbjct: 1733 KKKLETDIS-----------QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDT 1781 >gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapiens] Length = 693 Score = 48.5 bits (114), Expect = 2e-05 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 12/144 (8%) Query: 239 EHMKKMMKDLEGLHRAE----QSLHDL----QERLHKAQEEHRTVEVEKVHLEKKLRDEI 290 +H+++ ++ LEG +++ Q+L L ++RL + +E R EV++V +++L ++ Sbjct: 305 KHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQN 364 Query: 291 NLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSWYAPEALQ 348 +++ + L+E E + R + EE L + E L+K EK L + W E LQ Sbjct: 365 ERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQ 424 Query: 349 KWLQLTHEVEVQYYNIKKQNAEKQ 372 K Q Q + + KQ AE Q Sbjct: 425 K--QEERLALSQNHKLDKQLAEPQ 446 Score = 39.7 bits (91), Expect = 0.009 Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 1/129 (0%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL-RDEIN 291 QN +E K + + E L + EQ L +ERL K +E + E E++L + E Sbjct: 363 QNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEER 422 Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351 L KQE + + + + + + E+L +++ + E++++ E L+ Sbjct: 423 LQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAAS 482 Query: 352 QLTHEVEVQ 360 Q ++E Q Sbjct: 483 QQNQQLETQ 491 Score = 36.6 bits (83), Expect = 0.079 Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 8/103 (7%) Query: 237 SKEHMKKMMKDLEGLHRAEQSLHDLQERL----HKAQEEHRTVEVEKVHLEKKLRDEINL 292 SKE +++ + E L E QERL + +E+ +T++ + L K+ E L Sbjct: 332 SKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQ---EQRL 388 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL 335 KQE +RL++ E + + R EE L + E L+K E+ L Sbjct: 389 RKQE-ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430 >gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] Length = 841 Score = 48.1 bits (113), Expect = 3e-05 Identities = 39/157 (24%), Positives = 78/157 (49%), Gaps = 21/157 (13%) Query: 239 EHMKKMMKDLEGLHRAEQS----LHDLQERLHKAQEEHRTVEVEKVHLEKKLRD-EINLA 293 E K+ ++L G R E++ L LQ+ + + Q + +++ K E++L++ E +L Sbjct: 478 EDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQ 537 Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353 +Q+ ++ + L++ E + K EEEL+ VR+ L +A++E + H L+ L Sbjct: 538 QQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCH--------LKTISSL 589 Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 EV K + Q ++ K+G+ +K + L Sbjct: 590 KQEV--------KDTVDGQRILEKKGSAALKDLKRQL 618 Score = 37.7 bits (86), Expect = 0.036 Identities = 46/203 (22%), Positives = 89/203 (43%), Gaps = 15/203 (7%) Query: 235 RYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAK 294 R S E K M+ +L E+S H + + + E + V + E++LR+ L + Sbjct: 423 RKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGV-RARYERELRE---LHE 478 Query: 295 QEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY------APEALQ 348 + ++ +ELR E++R + E L+Q E L+ ++ W+ A E+LQ Sbjct: 479 DKKRQEEELRGQIREEKARTRELET-LQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQ 537 Query: 349 KWLQLTHEVEVQ---YYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDV 405 + Q E Q + + + E++L ++ E+ +++R+ T D V Sbjct: 538 QQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTV 597 Query: 406 DHKILTAKQALSEVTAALRERLH 428 D + + K+ S L+ +LH Sbjct: 598 DGQRILEKKG-SAALKDLKRQLH 619 Score = 30.0 bits (66), Expect = 7.4 Identities = 33/172 (19%), Positives = 69/172 (40%), Gaps = 23/172 (13%) Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291 +Q R +H ++ + + +Q L + L + +++ + +E + L+D+++ Sbjct: 263 LQQRKEADHKAQLART----QKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVS 318 Query: 292 LAKQEAQRLKE--------LREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYA 343 + +AQ E LR Q +EL +RE EL+ + Y Sbjct: 319 IQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYE 378 Query: 344 P---------EALQKWLQLTHEV--EVQYYNIKKQNAEKQLLVAKEGAEKIK 384 LQ+ L+ + ++Q +K+ ++L A++ AEK K Sbjct: 379 DLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRK 430 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/171 (26%), Positives = 78/171 (45%), Gaps = 16/171 (9%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 + + K+ K M+++E + E+ L+ L + +EE R E+ L+KK +E Sbjct: 620 EEKAKKKAAAKKMEEVEARRKQEEEARRLRW-LQQEEEERRHQEL----LQKKKEEEQER 674 Query: 293 AKQ--EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ-- 348 ++ EA+RL E RE E+ R++ E E+ + R+ E++L E LQ Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734 Query: 349 -------KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG 392 K L+L E + KK+ E+Q L ++ E+ +KK G Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAG 785 Score = 42.0 bits (97), Expect = 0.002 Identities = 34/151 (22%), Positives = 68/151 (45%), Gaps = 13/151 (8%) Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291 ++ + E +++ + + R E+ +ERL K + VE K +K++ + Sbjct: 545 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 604 Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351 ++ ++ KE E E++++K A +++E+V EA RK E+E +WL Sbjct: 605 QIDEKTEKAKE--ERLAEEKAKKKAAAKKMEEV-EARRKQEEEARR----------LRWL 651 Query: 352 QLTHEVEVQYYNIKKQNAEKQLLVAKEGAEK 382 Q E ++K+ E+Q + K K Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAK 682 Score = 40.4 bits (93), Expect = 0.005 Identities = 36/129 (27%), Positives = 63/129 (48%), Gaps = 6/129 (4%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQE--EHRTVEVEKVHLEKKLRDEINLAKQ 295 +E +++ K E AEQ + +E+ + QE E E E+ E++L ++ +Q Sbjct: 669 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 728 Query: 296 EA-QRLKELREGTENERSRQKYAEEELEQVR---EALRKAEKELESHSSWYAPEALQKWL 351 E Q +EL+E + R +++ + ELE+ + E R AE++L+ A EA Sbjct: 729 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788 Query: 352 QLTHEVEVQ 360 L V+VQ Sbjct: 789 ALNVTVDVQ 797 Score = 36.6 bits (83), Expect = 0.079 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 14/104 (13%) Query: 285 KLRDEINLAKQEAQRLKELREGTENER-SRQKYAEEELEQVREALRKAEKELESHSSWYA 343 ++ + + ++E QRL+ LR E E+ RQK E++ ++ E K E Sbjct: 527 RMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE----------- 575 Query: 344 PEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKR 387 E L+K LQ VE Q KK+ E++ E EK K++R Sbjct: 576 -ERLRKVLQARERVE-QMKEEKKKQIEQKFAQIDEKTEKAKEER 617 Score = 31.6 bits (70), Expect = 2.5 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 16/119 (13%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDL----QERLHKAQ--------EEHRTVEVEKV 280 Q R K K + + R EQ + QER + + E+ R E E++ Sbjct: 672 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 731 Query: 281 HLEKKLRDE---INLAKQEAQR-LKELREGTENERSRQKYAEEELEQVREALRKAEKEL 335 E++L++ + L K++ QR L+E ++ E +R ++ +EE E+ + A K L Sbjct: 732 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 790 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/171 (26%), Positives = 78/171 (45%), Gaps = 16/171 (9%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 + + K+ K M+++E + E+ L+ L + +EE R E+ L+KK +E Sbjct: 616 EEKAKKKAAAKKMEEVEARRKQEEEARRLRW-LQQEEEERRHQEL----LQKKKEEEQER 670 Query: 293 AKQ--EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ-- 348 ++ EA+RL E RE E+ R++ E E+ + R+ E++L E LQ Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730 Query: 349 -------KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFG 392 K L+L E + KK+ E+Q L ++ E+ +KK G Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAG 781 Score = 42.0 bits (97), Expect = 0.002 Identities = 34/151 (22%), Positives = 68/151 (45%), Gaps = 13/151 (8%) Query: 232 IQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEIN 291 ++ + E +++ + + R E+ +ERL K + VE K +K++ + Sbjct: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 600 Query: 292 LAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWL 351 ++ ++ KE E E++++K A +++E+V EA RK E+E +WL Sbjct: 601 QIDEKTEKAKE--ERLAEEKAKKKAAAKKMEEV-EARRKQEEEARR----------LRWL 647 Query: 352 QLTHEVEVQYYNIKKQNAEKQLLVAKEGAEK 382 Q E ++K+ E+Q + K K Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAK 678 Score = 40.4 bits (93), Expect = 0.005 Identities = 36/129 (27%), Positives = 63/129 (48%), Gaps = 6/129 (4%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQE--EHRTVEVEKVHLEKKLRDEINLAKQ 295 +E +++ K E AEQ + +E+ + QE E E E+ E++L ++ +Q Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724 Query: 296 EA-QRLKELREGTENERSRQKYAEEELEQVR---EALRKAEKELESHSSWYAPEALQKWL 351 E Q +EL+E + R +++ + ELE+ + E R AE++L+ A EA Sbjct: 725 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784 Query: 352 QLTHEVEVQ 360 L V+VQ Sbjct: 785 ALNVTVDVQ 793 Score = 36.2 bits (82), Expect = 0.10 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 14/131 (10%) Query: 258 LHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENER-SRQKY 316 LH +Q V K +++ ++ ++E QRL+ LR E E+ RQK Sbjct: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKV 555 Query: 317 AEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVA 376 E++ ++ E K E E L+K LQ VE Q KK+ E++ Sbjct: 556 EEDKRRRLEEVKLKRE------------ERLRKVLQARERVE-QMKEEKKKQIEQKFAQI 602 Query: 377 KEGAEKIKKKR 387 E EK K++R Sbjct: 603 DEKTEKAKEER 613 Score = 31.6 bits (70), Expect = 2.5 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 16/119 (13%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDL----QERLHKAQ--------EEHRTVEVEKV 280 Q R K K + + R EQ + QER + + E+ R E E++ Sbjct: 668 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 727 Query: 281 HLEKKLRDE---INLAKQEAQR-LKELREGTENERSRQKYAEEELEQVREALRKAEKEL 335 E++L++ + L K++ QR L+E ++ E +R ++ +EE E+ + A K L Sbjct: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 47.4 bits (111), Expect = 4e-05 Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 16/137 (11%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298 E +K + L L RAEQ + +ER + QE R +E+EK LEK+ E ++E + Sbjct: 374 EQQRKEQERLAQLERAEQ---ERKERERQEQERKRQLELEK-QLEKQRELE---RQREEE 426 Query: 299 RLKEL--REGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 R KE+ RE + E RQ+ E E + +E L + KE E + K + T E Sbjct: 427 RRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQED-------IVVLKAKKKTLE 479 Query: 357 VEVQYYNIKKQNAEKQL 373 E++ N KK E +L Sbjct: 480 FELEALNDKKHQLEGKL 496 Score = 45.1 bits (105), Expect = 2e-04 Identities = 48/203 (23%), Positives = 87/203 (42%), Gaps = 25/203 (12%) Query: 255 EQSLHDLQERLHKA------QEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKEL----- 303 E L D Q++L K ++ E + LEK+ + + ++E +RL +L Sbjct: 332 EPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQ 391 Query: 304 ----REGTENERSRQKYAEEELEQVREALRKAE----KELESHSSWYAPEALQKWLQLTH 355 RE E ER RQ E++LE+ RE R+ E KE+E + A L++ QL Sbjct: 392 ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREA--AKRELERQRQLEW 449 Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQA 415 E + + ++N E++ +V + +K + L D+ ++ T +Q Sbjct: 450 ERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQE 509 Query: 416 LSEVTAA----LRERLHRWQQIE 434 + + + E H QQ++ Sbjct: 510 IESTNKSRELRIAEITHLQQQLQ 532 Score = 37.7 bits (86), Expect = 0.036 Identities = 24/93 (25%), Positives = 54/93 (58%), Gaps = 8/93 (8%) Query: 245 MKDLEGLHRAEQSLHDLQ---ERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLK 301 +K+L +H +Q ERL + ++E + +E+EK E + R + +++ Q L+ Sbjct: 607 LKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQ----ERDKQWLE 662 Query: 302 ELREGTENERSRQKYAEEELEQVREALRKAEKE 334 +++ E++R R+ + EE+L++ E+++K + E Sbjct: 663 HVQQEDEHQRPRKLHEEEKLKR-EESVKKKDGE 694 Score = 34.3 bits (77), Expect = 0.39 Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 15/172 (8%) Query: 238 KEHMKKMMKDLE--GLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ 295 K+ + +K ++ LHR SL L+ L + + + + +EK+ R ++ Sbjct: 545 KQILNDQLKQVQQNSLHR--DSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDI 602 Query: 296 EAQRLKELRE-GTENERSRQKYAEEELEQVREALRK---AEKELESHSSWYAPEALQKWL 351 +LKELRE + + +QK E E + +E RK EK+ E + A E ++WL Sbjct: 603 FNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKE-EAQRRAQERDKQWL 661 Query: 352 QLTHEVEVQYYNIKKQNAEKQL-----LVAKEGAEKIKKKRNTLFGTFHVAH 398 + + E ++ +K + E++L + K+G EK K++ G H Sbjct: 662 EHVQQ-EDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH 712 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 47.4 bits (111), Expect = 4e-05 Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 16/137 (11%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298 E +K + L L RAEQ + +ER + QE R +E+EK LEK+ E ++E + Sbjct: 374 EQQRKEQERLAQLERAEQ---ERKERERQEQERKRQLELEK-QLEKQRELE---RQREEE 426 Query: 299 RLKEL--REGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 R KE+ RE + E RQ+ E E + +E L + KE E + K + T E Sbjct: 427 RRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQED-------IVVLKAKKKTLE 479 Query: 357 VEVQYYNIKKQNAEKQL 373 E++ N KK E +L Sbjct: 480 FELEALNDKKHQLEGKL 496 Score = 45.1 bits (105), Expect = 2e-04 Identities = 48/203 (23%), Positives = 87/203 (42%), Gaps = 25/203 (12%) Query: 255 EQSLHDLQERLHKA------QEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKEL----- 303 E L D Q++L K ++ E + LEK+ + + ++E +RL +L Sbjct: 332 EPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQ 391 Query: 304 ----REGTENERSRQKYAEEELEQVREALRKAE----KELESHSSWYAPEALQKWLQLTH 355 RE E ER RQ E++LE+ RE R+ E KE+E + A L++ QL Sbjct: 392 ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREA--AKRELERQRQLEW 449 Query: 356 EVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQA 415 E + + ++N E++ +V + +K + L D+ ++ T +Q Sbjct: 450 ERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQE 509 Query: 416 LSEVTAA----LRERLHRWQQIE 434 + + + E H QQ++ Sbjct: 510 IESTNKSRELRIAEITHLQQQLQ 532 Score = 37.7 bits (86), Expect = 0.036 Identities = 24/93 (25%), Positives = 54/93 (58%), Gaps = 8/93 (8%) Query: 245 MKDLEGLHRAEQSLHDLQ---ERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLK 301 +K+L +H +Q ERL + ++E + +E+EK E + R + +++ Q L+ Sbjct: 607 LKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQ----ERDKQWLE 662 Query: 302 ELREGTENERSRQKYAEEELEQVREALRKAEKE 334 +++ E++R R+ + EE+L++ E+++K + E Sbjct: 663 HVQQEDEHQRPRKLHEEEKLKR-EESVKKKDGE 694 Score = 34.3 bits (77), Expect = 0.39 Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 15/172 (8%) Query: 238 KEHMKKMMKDLE--GLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQ 295 K+ + +K ++ LHR SL L+ L + + + + +EK+ R ++ Sbjct: 545 KQILNDQLKQVQQNSLHR--DSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDI 602 Query: 296 EAQRLKELRE-GTENERSRQKYAEEELEQVREALRK---AEKELESHSSWYAPEALQKWL 351 +LKELRE + + +QK E E + +E RK EK+ E + A E ++WL Sbjct: 603 FNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKE-EAQRRAQERDKQWL 661 Query: 352 QLTHEVEVQYYNIKKQNAEKQL-----LVAKEGAEKIKKKRNTLFGTFHVAH 398 + + E ++ +K + E++L + K+G EK K++ G H Sbjct: 662 EHVQQ-EDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH 712 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 47.0 bits (110), Expect = 6e-05 Identities = 47/181 (25%), Positives = 79/181 (43%), Gaps = 18/181 (9%) Query: 237 SKEHMKKMMKDLEGLHR--------AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRD 288 S E KK+ DLE R A++S D++ + E+ + E E L+ K+ D Sbjct: 1041 SLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100 Query: 289 EINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQ 348 E L Q +++KEL ++R + EEE+E R + KAEK+ S S E + Sbjct: 1101 EQALGMQLQKKIKEL-------QARIEELEEEIEAERASRAKAEKQ-RSDLSRELEEISE 1152 Query: 349 KWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHK 408 + + Q KK+ AE Q + + E+ + T H+ S+ ++ + Sbjct: 1153 RLEEAGGATSAQIEMNKKREAEFQKM--RRDLEEATLQHEATAATLRKKHADSVAELGEQ 1210 Query: 409 I 409 I Sbjct: 1211 I 1211 Score = 37.4 bits (85), Expect = 0.046 Identities = 37/162 (22%), Positives = 80/162 (49%), Gaps = 31/162 (19%) Query: 240 HMKKMMKDLEGLHRAEQSLHDLQERLHKAQE-------------EHRTVEVE-KVHLEKK 285 H+++M K+LE Q++ DLQ RL +A++ E R E+E +V E+K Sbjct: 1782 HLERMKKNLE------QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1835 Query: 286 LRDE-INLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAP 344 E + ++ +++KEL TE +R ++ +++++ ++ +++ E + + Sbjct: 1836 RNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE-EAEEQSN 1894 Query: 345 EALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 L K+ ++ HE+E AE++ +A+ K++ K Sbjct: 1895 VNLSKFRRIQHELE---------EAEERADIAESQVNKLRVK 1927 Score = 36.2 bits (82), Expect = 0.10 Identities = 42/203 (20%), Positives = 90/203 (44%), Gaps = 23/203 (11%) Query: 239 EHMKKMMKDLEGLHRA-EQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 E + K+ K+ + L A +Q+L DLQ +++ T+ K+ LE+++ D +QE Sbjct: 991 ETIAKLTKEKKALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1046 Query: 298 QRLKELREGTENERSRQKYAEE-------ELEQVREALRKAEKELESHSSWYAPEALQKW 350 + +L K A+E + +Q+ E L+K E E+ S E + Sbjct: 1047 KIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDE---QA 1103 Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKIL 410 L + + +++ + + E+++ + K +K+R+ L S L+++ ++ Sbjct: 1104 LGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL--------SRELEEISERLE 1155 Query: 411 TAKQALSEVTAALRERLHRWQQI 433 A A S ++R +Q++ Sbjct: 1156 EAGGATSAQIEMNKKREAEFQKM 1178 Score = 36.2 bits (82), Expect = 0.10 Identities = 48/210 (22%), Positives = 91/210 (43%), Gaps = 46/210 (21%) Query: 237 SKEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHRTVEV----EKVHLEKKLRDEIN 291 S+ ++ K +EG L+ E L+ +A +R + ++HL+ LR + + Sbjct: 1611 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQED 1670 Query: 292 LAKQEAQ----------RLKELREGTENERSRQKYAEEELEQVRE----------ALRKA 331 L +Q A ++ELR E +K AE+EL E +L Sbjct: 1671 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1730 Query: 332 EKELESHSSWYAPEALQKWLQLTHEVE--VQYYNIKKQNAEKQLLVAKEGAEKIKKKRNT 389 +K+LE+ S Q+ E+E +Q ++ A+K + A AE++KK+++T Sbjct: 1731 KKKLETDIS-----------QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDT 1779 Query: 390 LFGTFHVAH-----SSSLDDVDHKILTAKQ 414 + H+ ++ D+ H++ A+Q Sbjct: 1780 ---SAHLERMKKNLEQTVKDLQHRLDEAEQ 1806 Score = 35.8 bits (81), Expect = 0.14 Identities = 43/185 (23%), Positives = 83/185 (44%), Gaps = 26/185 (14%) Query: 241 MKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL------RDEINLAK 294 +K ++K E E+ + +++E K +EE E ++ LE+K+ ++++ L Sbjct: 840 IKPLLKSAE----TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV 895 Query: 295 Q-EAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353 Q EA L + E + + E ++++V E +AE E E ++ A + Sbjct: 896 QAEADSLADAEERCDQLIKTKIQLEAKIKEVTE---RAEDEEEINAELTAKK-------- 944 Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAK 413 ++E + +KK + +L +AK EK + T +A LD+ K+ K Sbjct: 945 -RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMA---GLDETIAKLTKEK 1000 Query: 414 QALSE 418 +AL E Sbjct: 1001 KALQE 1005 Score = 35.4 bits (80), Expect = 0.18 Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 17/147 (11%) Query: 239 EHMKKMMKDLEGLH-----------RAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLR 287 E +KK ++ GL + ++ + +LQ R+ + +EE + EK+ Sbjct: 1082 EKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141 Query: 288 DEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEAL 347 D ++ ++RL+E T + K E E +++R L +A + E+ ++ + Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1201 Query: 348 QKWLQLTHEVEVQYYNIK--KQNAEKQ 372 +L +++ N++ KQ EK+ Sbjct: 1202 DSVAELGEQID----NLQRVKQKLEKE 1224 Score = 33.1 bits (74), Expect = 0.88 Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 11/113 (9%) Query: 274 TVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEK 333 T ++E+ L+++L +EI A L+ R + R + + +E +++ A+ KA Sbjct: 1313 TQQIEE--LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANS 1370 Query: 334 ELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKK 386 E+ + Y +A+Q+ T E+E KK+ A++ L A+E E + K Sbjct: 1371 EVAQWRTKYETDAIQR----TEELE----EAKKKLAQR-LQDAEEHVEAVNAK 1414 Score = 30.0 bits (66), Expect = 7.4 Identities = 47/230 (20%), Positives = 92/230 (40%), Gaps = 46/230 (20%) Query: 251 LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENE 310 L R +Q+ E L + EE + H + R + +L +++ + +E + + Sbjct: 1305 LSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRA 1364 Query: 311 RS---------RQKYAE------EELEQVREALRKAEKELESHSSWYAPE--ALQKWLQ- 352 S R KY EELE+ ++ L + ++ E H + +L+K Q Sbjct: 1365 MSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQR 1424 Query: 353 LTHEVEVQYYNIKKQNAEKQLLVAK----------------------EGAEKIKKKRNTL 390 L +EVE ++++ NA L K E ++K + +T Sbjct: 1425 LQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTE 1484 Query: 391 FGTFHVAHSSSLDDVD---HKILTAKQALSEVTAALRE---RLHRWQQIE 434 A+ SLD ++ + +Q +S++T + E R+H ++I+ Sbjct: 1485 LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIK 1534 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 46.6 bits (109), Expect = 8e-05 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 22/168 (13%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298 E +KM + E + E+ + +L+E++H+ QE+ R E EK E+K+R++ +QEA+ Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIREQE-EKRQEEEKIREQEKRQEQEAK 431 Query: 299 RLKE---LREGTENERSRQK--YAEEEL----EQVREALRKAEKELESHSSWYAPEALQK 349 ++ +RE E R ++K + +EE E++RE EK E W E + + Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE----EKRQEQEEMWRQEEKIHE 487 Query: 350 ----WLQLTHEVEVQYYNIKKQNAE--KQLLVAKEGAEKIKKKRNTLF 391 W Q ++ Q I+KQ + +Q +E EKI+++ ++ Sbjct: 488 QEEIWRQ-KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534 Score = 44.3 bits (103), Expect = 4e-04 Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 5/148 (3%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + E + E+ + +E + + +E+ R E E+K+R + + Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385 Query: 293 AKQEAQRLKELREGT-ENERSRQKYAEEELEQVREALRKAEKELESHSS-WYAPEALQKW 350 ++ ++++EL E E E+ R+ +EE Q E +R+ EK E + W E +++ Sbjct: 386 MWEKEEKIRELEEKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442 Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKE 378 + E E + + +++ E++ + +E Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEE 470 Score = 43.5 bits (101), Expect = 6e-04 Identities = 45/222 (20%), Positives = 95/222 (42%), Gaps = 25/222 (11%) Query: 233 QNRYSKEHMKKMMKDLEGLH-----RAEQSLHDLQERLHKAQEEHRTVEV----EKVH-L 282 Q +E KKM + E +H R E+ + +E + ++ H E+ EK+H Sbjct: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501 Query: 283 EKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY 342 E+K+R + ++ ++++E E + + EE++ + E R+ EK E W Sbjct: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561 Query: 343 APEALQK----WLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAH 398 + ++ W Q E +++ K E+++ +E EK +++ ++ Sbjct: 562 EEKRQEQEDKMWRQ---EEKIREQEEKVWRQEEKI---REQEEKRQEQEEKMW-----KQ 610 Query: 399 SSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQ 440 + + + KI ++ + E +RE+ Q+ E G Q Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652 Score = 43.1 bits (100), Expect = 8e-04 Identities = 47/226 (20%), Positives = 104/226 (46%), Gaps = 27/226 (11%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL-RDEIN 291 Q E +K+ K E + R E+ + + +E++ + QEE + EK+ ++++ R+E Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI-REQEEKMWRQEEKIREQEEMWREEEK 552 Query: 292 LAKQEAQRLKELREGTENERSRQ----KYAEEELEQVREALRKAE--KELESHSSWYAPE 345 + +QE +E R+ E++ RQ + EE++ + E +R+ E ++ + W E Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612 Query: 346 AL----QKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEG---------AEKIKKKRNTLFG 392 + +K + ++ Q I++Q Q K G EK++++ T++ Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW- 671 Query: 393 TFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHR-WQQIEILC 437 + + + KI ++ + E ++E+ + W+Q E +C Sbjct: 672 ----RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713 Score = 42.7 bits (99), Expect = 0.001 Identities = 44/206 (21%), Positives = 95/206 (46%), Gaps = 27/206 (13%) Query: 244 MMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-LEKKLRDEINLAKQEAQRLKE 302 M + E + R E+ + + +E++ + QEE + EK+ LE+K+ ++ + +QE +R +E Sbjct: 358 MWEKEEKMRRQEEMMWEKEEKMRR-QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 416 Query: 303 LREGTENERSRQKYA-----EEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357 + E E+ +++ A EE++ + E +R+ EK++ W E + + ++ E Sbjct: 417 -EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM-----WRQEEKIHEQEKIREEE 470 Query: 358 EVQYYNIKKQNAEK---------QLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHK 408 + Q + EK Q E EKI+K+ ++ + + + K Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW-----RQEEKIREQEEK 525 Query: 409 ILTAKQALSEVTAALRERLHRWQQIE 434 I ++ + +RE+ W++ E Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEE 551 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/161 (16%), Positives = 79/161 (49%), Gaps = 3/161 (1%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +K+ + E + E+ + +E++ K +E+ R E + E+K+R++ Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWY--APEALQKW 350 +++ + +E E + + EE++++ E + + E+++ E +++ Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694 Query: 351 LQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLF 391 ++ E E + + +++ E++ + +E EK++++ ++ Sbjct: 695 EEMMQEQEEKMWEQEEKMCEQEEKM-QEQEEKMRRQEEKMW 734 Score = 40.8 bits (94), Expect = 0.004 Identities = 36/196 (18%), Positives = 87/196 (44%), Gaps = 13/196 (6%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEA 297 +E KM + E + E+ + +E++ + +E+ + E + E+K+R++ +++ Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625 Query: 298 QRLKELREG-TENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 ++++E E E E Q+ E+ EQ + + EK E + + E +K + + Sbjct: 626 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE--EKIREQEKK 683 Query: 357 VEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQAL 416 + Q I++Q Q E EK+ ++ + + + + K+ ++ + Sbjct: 684 IREQEEKIREQEEMMQ-----EQEEKMWEQEEKM-----CEQEEKMQEQEEKMRRQEEKM 733 Query: 417 SEVTAALRERLHRWQQ 432 E LR++ + Q+ Sbjct: 734 WEQEVRLRQQEEKMQE 749 Score = 39.7 bits (91), Expect = 0.009 Identities = 22/113 (19%), Positives = 58/113 (51%), Gaps = 7/113 (6%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q ++E +KM + E + E+ + + +E + + +E+ R E + E+K+R++ + Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVRE-------ALRKAEKELESH 338 +++ +++ E E + + + EE++ + E LR+ E++++ H Sbjct: 698 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750 Score = 37.4 bits (85), Expect = 0.046 Identities = 29/151 (19%), Positives = 68/151 (45%), Gaps = 18/151 (11%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH---------------LE 283 +H+ K ++ + +A+ ++L RL++ QEE + EK+ E Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327 Query: 284 KKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKEL--ESHSSW 341 +K+R++ +++ + + E E + EE++ + E + + E+++ + W Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387 Query: 342 YAPEALQKWLQLTHEVE-VQYYNIKKQNAEK 371 E +++ + HE E ++ K+Q EK Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418 Score = 36.2 bits (82), Expect = 0.10 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 11/157 (7%) Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293 +RY +E K+ L+R + +L+E+ K QE+ + VE EK EI L Sbjct: 192 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--------SEIQLN 243 Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353 +E +R E + ++ Q A+ ++++ K + ++E + W Q+ Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303 Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 E ++Q + K Q E+++ +E EKI+++ + Sbjct: 304 RQEEKIQEWEEKIQEQEEKI---REQEEKIREQEEKM 337 Score = 32.3 bits (72), Expect = 1.5 Identities = 29/157 (18%), Positives = 64/157 (40%), Gaps = 26/157 (16%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL------ 286 Q +E +KM K E + E+ + + +E++ + +E+ R E E+K+ Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655 Query: 287 ----------------RDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRK 330 R E + +QE ++++E E + + EE++ + E + + Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQE-KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714 Query: 331 AEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQ 367 E++++ + + W Q EV ++ K Q Sbjct: 715 QEEKMQEQEEKMRRQEEKMWEQ---EVRLRQQEEKMQ 748 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 46.2 bits (108), Expect = 1e-04 Identities = 32/191 (16%), Positives = 93/191 (48%), Gaps = 12/191 (6%) Query: 242 KKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLK 301 K+ M + E + + E+ + +E++H +E+ R E + E+K+R++ +++ ++++ Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540 Query: 302 ELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQY 361 E E + + + EE++++ + R+ EK E E +++ + E E + Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE------EKIREQKEKIREQEEKI 594 Query: 362 YNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTA 421 + +++ E++ ++ +E EK+ ++ + + + + K+ ++ + E Sbjct: 595 WEQEEKIREQEEMM-QEQEEKMWEQEEKM-----CEQEEKMQEQEEKMRRQEEKMWEQEV 648 Query: 422 ALRERLHRWQQ 432 LR++ + Q+ Sbjct: 649 RLRQQEEKMQE 659 Score = 44.3 bits (103), Expect = 4e-04 Identities = 29/162 (17%), Positives = 83/162 (51%), Gaps = 8/162 (4%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +KM + E + E+ + + +E++ + +E + E + E+K++++ + Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSS--WYAPEALQKW 350 +QE ++++E E ++ + + EE++ + E +R+ E+ ++ W E +K Sbjct: 567 RRQE-EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW---EQEEKM 622 Query: 351 LQLTHEVEVQYYNIKKQNAE--KQLLVAKEGAEKIKKKRNTL 390 + +++ Q +++Q + +Q + ++ EK+++ + L Sbjct: 623 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664 Score = 43.9 bits (102), Expect = 5e-04 Identities = 28/137 (20%), Positives = 69/137 (50%), Gaps = 4/137 (2%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKV-HLEKKLRDEINLAKQEA 297 +H+ K ++ + +A+ ++L RL++ QEE + EK+ E+K++++ +++ Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELE--SHSSWYAPEALQKWLQLTH 355 ++++E E + EE++ + E + + E+++ W E +++ + H Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387 Query: 356 EVE-VQYYNIKKQNAEK 371 E E ++ K+Q EK Sbjct: 388 EQEKIREQEEKRQEEEK 404 Score = 43.9 bits (102), Expect = 5e-04 Identities = 42/205 (20%), Positives = 96/205 (46%), Gaps = 16/205 (7%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQ 298 E +KM + E + E+ + L+E + + +E+ R +E EK+H ++K+R+ QE + Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE-EKMHEQEKIRE------QEEK 398 Query: 299 RLKELREGTENERSRQK----YAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLT 354 R +E + + +R Q+ EE++ + E +R+ EK++ + + + Sbjct: 399 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458 Query: 355 HEVEVQYYNIKKQNAEKQLLVAKE---GAEKIKKKRNTLFGTFHVAH--SSSLDDVDHKI 409 E E + +K ++++ KE EKI+K+ ++ H + + + K+ Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518 Query: 410 LTAKQALSEVTAALRERLHRWQQIE 434 ++ + E +RE+ + ++ E Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQE 543 Score = 43.9 bits (102), Expect = 5e-04 Identities = 42/211 (19%), Positives = 103/211 (48%), Gaps = 17/211 (8%) Query: 233 QNRYSKEHMKKMMKDLEG---LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDE 289 + R +E +++ K E + R E+ + + +E++ + QE+ + EK+H ++K+R+E Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-QEKKMWRQEEKIHEQEKIREE 455 Query: 290 INLAKQEA--QRLKELREGTENERSRQK-YAEEELEQVREALRKAEKELESHSSWYAPEA 346 +QE ++ +++RE E R ++K + +E++ + E + + E+++ + Sbjct: 456 EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE 515 Query: 347 LQKWLQLTHEVEVQYYNIKKQNAE--KQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDD 404 + W Q ++ Q I++Q + +Q + +E EK+ ++ + + Sbjct: 516 EKMWRQ-EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM------QEQEKMRR 568 Query: 405 VDHKILTAKQALSEVTAALRERLHR-WQQIE 434 + KI ++ + E +RE+ + W+Q E Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEE 599 Score = 40.0 bits (92), Expect = 0.007 Identities = 46/232 (19%), Positives = 100/232 (43%), Gaps = 31/232 (13%) Query: 234 NRYSKEHMKKMMKDLEGLHR-------AEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKL 286 NR +++ +KM + E + E+ + + +E++ + +E+ R E E+K+ Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351 Query: 287 R--DEINLAKQEAQRLKE---------LREGTENERSRQKYAE-EELEQVREALRKAEKE 334 R +E+ K+E R E +RE E ++K E EE Q E +R+ EK Sbjct: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 411 Query: 335 LESHSS-WYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKE----------GAEKI 383 E + W E +++ + E E + + +++ E++ + +E EKI Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471 Query: 384 KKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHR-WQQIE 434 +++ + + + K+ ++ + + +RE+ + W+Q E Sbjct: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523 Score = 36.2 bits (82), Expect = 0.10 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 11/157 (7%) Query: 234 NRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA 293 +RY +E K+ L+R + +L+E+ K QE+ + VE EK EI L Sbjct: 192 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK--------SEIQLN 243 Query: 294 KQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQL 353 +E +R E + ++ Q A+ ++++ K + ++E + W Q+ Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303 Query: 354 THEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTL 390 E ++Q + K Q E+++ +E EKI+++ + Sbjct: 304 RQEEKIQEWEEKIQEQEEKI---REQEEKIREQEEKM 337 Score = 34.3 bits (77), Expect = 0.39 Identities = 17/99 (17%), Positives = 50/99 (50%) Query: 233 QNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINL 292 Q +E +K+ + E + E+ + + +E++ + +E + E + E+K+ ++ Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628 Query: 293 AKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKA 331 +++ ++++ E + R + EE++++ +E L A Sbjct: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667 >gi|226371725 FCH domain only 2 isoform b [Homo sapiens] Length = 777 Score = 46.2 bits (108), Expect = 1e-04 Identities = 83/384 (21%), Positives = 148/384 (38%), Gaps = 60/384 (15%) Query: 276 EVEKVHLEKKLRDEINLAKQEAQRLKELRE-GTENERSRQKYAEE---------ELEQVR 325 +V K EK ++L ++ + +KE+++ G E +S +K EE ++ + Sbjct: 74 DVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSIT 133 Query: 326 EALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIK- 384 +AL+K+++ ++ E L+K E+E KK +L V K K Sbjct: 134 QALQKSKENY--NAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALAKADF 191 Query: 385 KKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNN 444 +++ T H +++ + + L K A S+ T R L +++ + + + Sbjct: 192 EQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGI-K 250 Query: 445 PGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLT 504 P A I + A + D D ++ + + + S++ Q T Sbjct: 251 PRKRKTFALPGI------IKKEKDAESVECPDADSLN---IPDVDEEGYSIKPETNQNDT 301 Query: 505 EPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVH 564 + H S SDS+S + R+ KP M N SH + + Sbjct: 302 KENHFYSS------SDSDSEDEEPKKYRIEIKP-------------MHPNNSHHTMASLD 342 Query: 565 PGSL-VEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGG-------------SPH 610 + + + SPA+++ + + +N L L + PSAPP P Sbjct: 343 ELKVSIGNITLSPAISRHSPVQMNRNLSN-EELTKSKPSAPPNEKGTSDLLAWDPLFGPS 401 Query: 611 LDSSRSH---SPSSPDPDTPSPVG 631 LDSS S S SS P TP VG Sbjct: 402 LDSSSSSSLTSSSSARPTTPLSVG 425 >gi|34878904 synaptonemal complex protein 1 [Homo sapiens] Length = 976 Score = 46.2 bits (108), Expect = 1e-04 Identities = 84/397 (21%), Positives = 162/397 (40%), Gaps = 50/397 (12%) Query: 52 DKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGE 111 +K SE+ K S E ++ K ++D + + L EDL T+ T E Sbjct: 301 EKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLT---E 357 Query: 112 DKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTN 171 +K +E+ KA +++ V E + + EL + E+ ++L+ + + L + Sbjct: 358 EKETQMEESNKA---RAAHSFVVTEFETTVCSLEELLRTEQ--QRLEKNEDQLKILTMEL 412 Query: 172 TTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAY 231 + + +MT ++ ++++L+ L VL L N K F + + G Sbjct: 413 QKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYEN--KQFEKIAEELKGTEQELIGL 470 Query: 232 IQNRY---------------SKEHMKKMMKDLEG-LHRAEQSLHDLQERLHKAQEEHR-- 273 +Q R S+++ K +KDL+ L + +L +K E++ Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKEL 530 Query: 274 TVEVEKVHLEKKLRDEI--NLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKA 331 T E + LE K + E N KQE + LK++ EN + + ELE VRE L++ Sbjct: 531 TQETSDMTLELKNQQEDINNNKKQEERMLKQI----ENLQETETQLRNELEYVREELKQK 586 Query: 332 EKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAK-EGAEKIKKKRNTL 390 E++ + E N++KQ K + + + K KK+ T Sbjct: 587 RDEVKCK---------------LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTA 631 Query: 391 FGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERL 427 + ++ ++ ++ +AKQ E+T ++ + Sbjct: 632 ESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEI 668 Score = 36.2 bits (82), Expect = 0.10 Identities = 34/144 (23%), Positives = 71/144 (49%), Gaps = 6/144 (4%) Query: 251 LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENE 310 +++ E L +++ + + ++ +K E+ L +E+ AK A +L++ + + Sbjct: 643 VNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEID-K 701 Query: 311 RSRQKYAEEE--LEQVREALRKAEKELESHSSWY-APEALQKWLQLTHEVEVQYYNIKKQ 367 R + K AE +E+ + K +E +S Y + E Q L+ + E+E+ + Sbjct: 702 RCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELL 761 Query: 368 NAEKQLLVAKEGAEKIKK--KRNT 389 + +KQL + +E EK+K+ K NT Sbjct: 762 SVKKQLEIEREEKEKLKREAKENT 785 Score = 35.0 bits (79), Expect = 0.23 Identities = 50/227 (22%), Positives = 92/227 (40%), Gaps = 46/227 (20%) Query: 245 MKDLEGL-HRAEQSLHDLQERLHKAQEEHRTVEVEKVH------------------LEKK 285 MKDL L + ++ L+E+ K Q E+ +EK H +K Sbjct: 282 MKDLTFLLEESRDKVNQLEEKT-KLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKA 340 Query: 286 LRDEINLAKQEAQRLKELREGTENERSRQKYA--------EEELEQVREALRKAEKELES 337 L +++ +A + +L E +E E ++ + A E + + E LR ++ LE Sbjct: 341 LEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEK 400 Query: 338 HSSWY---------APEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEG-----AEKI 383 + L++ +LT+ EV+ +KK EK+ L+ + AE++ Sbjct: 401 NEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEEL 460 Query: 384 KKKRNTLFGTFHVAHSSSLDDVDHK---ILTAKQALSEVTAALRERL 427 K L G A + D++ + I T++Q S+ L+ L Sbjct: 461 KGTEQELIGLLQ-AREKEVHDLEIQLTAITTSEQYYSKEVKDLKTEL 506 Score = 31.6 bits (70), Expect = 2.5 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 12/96 (12%) Query: 295 QEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLT 354 +EA+++K+ + TE E +++ +E ++ EA RKA +EL+ + E + L+L Sbjct: 111 KEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQ-----FGNEKVS--LKLE 163 Query: 355 HEVEVQYYNIKKQNAEKQLL-----VAKEGAEKIKK 385 ++ IK+ NA + L AEK KK Sbjct: 164 EGIQENKDLIKENNATRHLCNLLKETCARSAEKTKK 199 Score = 29.6 bits (65), Expect = 9.7 Identities = 35/155 (22%), Positives = 67/155 (43%), Gaps = 23/155 (14%) Query: 246 KDLEGLHRAEQSLHDL-QERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELR 304 KDL + A + L +L +E ++ E+ + E E+ + D N ++ +ELR Sbjct: 170 KDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELR 229 Query: 305 EGTENERSRQKY-AEEELEQVREALRKAEKELESHS--------------------SWYA 343 EN R + +E+ E+++ ++ +KE+ ++ Sbjct: 230 VQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLL 289 Query: 344 PEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKE 378 E+ K QL + ++Q N+ KQ+ EKQ + KE Sbjct: 290 EESRDKVNQLEEKTKLQSENL-KQSIEKQHHLTKE 323 >gi|118498356 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/152 (24%), Positives = 77/152 (50%), Gaps = 9/152 (5%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEI-NLAKQEA 297 E +KK++ + +G ++ + L L+ L K + +TV+ K + K L++EI N+ ++A Sbjct: 797 EELKKVIHEKDGKIKSVEEL--LEAELLKVANKEKTVQDLKQEI-KALKEEIGNVQLEKA 853 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357 Q+L + + ++ K EE++ ++ L + EK+L + W + H Sbjct: 854 QQLS-ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912 Query: 358 EVQYYNIKKQNAEKQL----LVAKEGAEKIKK 385 EV +N+K+ ++ Q +V KE ++K+ Sbjct: 913 EVAQHNLKEASSASQFEELEIVLKEKENELKR 944 Score = 44.3 bits (103), Expect = 4e-04 Identities = 46/181 (25%), Positives = 85/181 (46%), Gaps = 24/181 (13%) Query: 239 EHMKKMMKDLEG-LHRAEQSLHDLQERLH-KAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296 E K ++ + EG L + ++S+ + + K E H+T+ K+++ ++QE Sbjct: 1137 EKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQE 1188 Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 +RL+ + EN R +++ E ELE KAE E ++ + E +L + Sbjct: 1189 LERLRSENKDIENLRREREHLEMELE-------KAEMERSTYVT-EVRELKDLLTELQKK 1240 Query: 357 VEVQYYNIKKQNAEKQLLVAK--EGAEKIKKKRN---TLFGTFHVAHSSSLDDVDHKILT 411 ++ Y +QN E LL A+ E K++ ++N + G H A SL+ + KI+ Sbjct: 1241 LDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKA-QQSLELIQSKIVK 1299 Query: 412 A 412 A Sbjct: 1300 A 1300 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 22/192 (11%) Query: 245 MKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELR 304 MKD G E ++ Q ++H + +E + ++++ + +++ EI KQE L++ Sbjct: 376 MKDRIGTLEKEHNV--FQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAV 433 Query: 305 EGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQK--WLQLTHEVEVQYY 362 T N+ ++ A EL ++R+ + EL + E +QK Q +++VQ Sbjct: 434 SNTTNQLESKQSA--ELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQ 491 Query: 363 NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAA 422 +++ E Q + K AE H ++ D+ K + + + + + Sbjct: 492 EAERRWEEVQSYIRKRTAE----------------HEAAQQDLQSKFVAKENEVQSLHSK 535 Query: 423 LRERLHRWQQIE 434 L + L QQ+E Sbjct: 536 LTDTLVSKQQLE 547 Score = 29.6 bits (65), Expect = 9.7 Identities = 18/75 (24%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Query: 251 LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA---KQEAQRLKELREGT 307 LH+A+QSL +Q ++ KA + +E V E + ++ ++ Q +L++L + Sbjct: 1283 LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAV 1342 Query: 308 ENERSRQKYAEEELE 322 + +++K + LE Sbjct: 1343 NQQLTKEKEHYQVLE 1357 >gi|118498368 kinectin 1 isoform c [Homo sapiens] Length = 1300 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/152 (24%), Positives = 77/152 (50%), Gaps = 9/152 (5%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEI-NLAKQEA 297 E +KK++ + +G ++ + L L+ L K + +TV+ K + K L++EI N+ ++A Sbjct: 797 EELKKVIHEKDGKIKSVEEL--LEAELLKVANKEKTVQDLKQEI-KALKEEIGNVQLEKA 853 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357 Q+L + + ++ K EE++ ++ L + EK+L + W + H Sbjct: 854 QQLS-ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912 Query: 358 EVQYYNIKKQNAEKQL----LVAKEGAEKIKK 385 EV +N+K+ ++ Q +V KE ++K+ Sbjct: 913 EVAQHNLKEASSASQFEELEIVLKEKENELKR 944 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 22/192 (11%) Query: 245 MKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELR 304 MKD G E ++ Q ++H + +E + ++++ + +++ EI KQE L++ Sbjct: 376 MKDRIGTLEKEHNV--FQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAV 433 Query: 305 EGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQK--WLQLTHEVEVQYY 362 T N+ ++ A EL ++R+ + EL + E +QK Q +++VQ Sbjct: 434 SNTTNQLESKQSA--ELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQ 491 Query: 363 NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAA 422 +++ E Q + K AE H ++ D+ K + + + + + Sbjct: 492 EAERRWEEVQSYIRKRTAE----------------HEAAQQDLQSKFVAKENEVQSLHSK 535 Query: 423 LRERLHRWQQIE 434 L + L QQ+E Sbjct: 536 LTDTLVSKQQLE 547 Score = 37.4 bits (85), Expect = 0.046 Identities = 46/212 (21%), Positives = 87/212 (41%), Gaps = 35/212 (16%) Query: 239 EHMKKMMKDLEG-LHRAEQSLHDLQERLH-KAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296 E K ++ + EG L + ++S+ + + K E H+T+ K+++ ++QE Sbjct: 1108 EKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQE 1159 Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 +RL+ + EN R +++ E ELE KAE E S Y E + QL Sbjct: 1160 LERLRSENKDIENLRREREHLEMELE-------KAEME----RSTYVTEVRELKAQLNET 1208 Query: 357 V-EVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLD------------ 403 + +++ ++Q L A++ E I+ K G V +S + Sbjct: 1209 LTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMS 1268 Query: 404 -DVDHKILTAKQALSEVTAALRERLHRWQQIE 434 ++ + +Q L V L + +Q +E Sbjct: 1269 VSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE 1300 >gi|33620775 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/152 (24%), Positives = 77/152 (50%), Gaps = 9/152 (5%) Query: 239 EHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEI-NLAKQEA 297 E +KK++ + +G ++ + L L+ L K + +TV+ K + K L++EI N+ ++A Sbjct: 797 EELKKVIHEKDGKIKSVEEL--LEAELLKVANKEKTVQDLKQEI-KALKEEIGNVQLEKA 853 Query: 298 QRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEV 357 Q+L + + ++ K EE++ ++ L + EK+L + W + H Sbjct: 854 QQLS-ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912 Query: 358 EVQYYNIKKQNAEKQL----LVAKEGAEKIKK 385 EV +N+K+ ++ Q +V KE ++K+ Sbjct: 913 EVAQHNLKEASSASQFEELEIVLKEKENELKR 944 Score = 44.3 bits (103), Expect = 4e-04 Identities = 46/181 (25%), Positives = 85/181 (46%), Gaps = 24/181 (13%) Query: 239 EHMKKMMKDLEG-LHRAEQSLHDLQERLH-KAQEEHRTVEVEKVHLEKKLRDEINLAKQE 296 E K ++ + EG L + ++S+ + + K E H+T+ K+++ ++QE Sbjct: 1137 EKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQE 1188 Query: 297 AQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHE 356 +RL+ + EN R +++ E ELE KAE E ++ + E +L + Sbjct: 1189 LERLRSENKDIENLRREREHLEMELE-------KAEMERSTYVT-EVRELKDLLTELQKK 1240 Query: 357 VEVQYYNIKKQNAEKQLLVAK--EGAEKIKKKRN---TLFGTFHVAHSSSLDDVDHKILT 411 ++ Y +QN E LL A+ E K++ ++N + G H A SL+ + KI+ Sbjct: 1241 LDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKA-QQSLELIQSKIVK 1299 Query: 412 A 412 A Sbjct: 1300 A 1300 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 22/192 (11%) Query: 245 MKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELR 304 MKD G E ++ Q ++H + +E + ++++ + +++ EI KQE L++ Sbjct: 376 MKDRIGTLEKEHNV--FQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAV 433 Query: 305 EGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQK--WLQLTHEVEVQYY 362 T N+ ++ A EL ++R+ + EL + E +QK Q +++VQ Sbjct: 434 SNTTNQLESKQSA--ELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQ 491 Query: 363 NIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAA 422 +++ E Q + K AE H ++ D+ K + + + + + Sbjct: 492 EAERRWEEVQSYIRKRTAE----------------HEAAQQDLQSKFVAKENEVQSLHSK 535 Query: 423 LRERLHRWQQIE 434 L + L QQ+E Sbjct: 536 LTDTLVSKQQLE 547 Score = 29.6 bits (65), Expect = 9.7 Identities = 18/75 (24%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Query: 251 LHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLA---KQEAQRLKELREGT 307 LH+A+QSL +Q ++ KA + +E V E + ++ ++ Q +L++L + Sbjct: 1283 LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAV 1342 Query: 308 ENERSRQKYAEEELE 322 + +++K + LE Sbjct: 1343 NQQLTKEKEHYQVLE 1357 >gi|22758136 MAP7 domain containing 2 [Homo sapiens] Length = 732 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 9/129 (6%) Query: 262 QERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEEL 321 Q RL K QEE VE E+ + +L E K E +RL+ E + E R++ EE+ Sbjct: 410 QARLQKEQEEQERVEKEE---QDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKK 466 Query: 322 EQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAE 381 +Q E RKA +E + + E L K Q + E +K+ AE + A+E AE Sbjct: 467 KQEGEEKRKAGEEAKRKAE---EELLLKEKQEQEKQEKAMIEKQKEAAETK---AREVAE 520 Query: 382 KIKKKRNTL 390 +++ +R + Sbjct: 521 QMRLEREQI 529 Score = 37.7 bits (86), Expect = 0.036 Identities = 38/160 (23%), Positives = 79/160 (49%), Gaps = 14/160 (8%) Query: 276 EVEKVHLEKKLRDEINLAKQEAQRL-KELREGTENERSRQKYAEEELEQVREALRKAEKE 334 E K+ EK+ + + ++E +R+ KE ++ E E ++K AEEE ++ E RK E+E Sbjct: 399 EAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRK-AEEERLRLEEEARKQEEE 457 Query: 335 LESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTF 394 + + ++ + E K+ AE++LL+ KE E+ K+++ + Sbjct: 458 RKRQEEEKKKQEGEEKRKAGEEA--------KRKAEEELLL-KEKQEQEKQEKAMIEKQK 508 Query: 395 HVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIE 434 A + + + + L +Q + ++ +ERL R ++I+ Sbjct: 509 EAAETKAREVAEQMRLEREQIMLQIE---QERLERKKRID 545 Score = 35.8 bits (81), Expect = 0.14 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 16/104 (15%) Query: 260 DLQERLHKAQEEHRT---VEVEKVHLEKKLRDEINLAKQEAQRLKELREGTE-------- 308 D ++RL K + E R E+ LEK+ R + KQ +R ++L E + Sbjct: 52 DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAA 111 Query: 309 -NERSRQKYAEEE--LE-QVREALRKAEK-ELESHSSWYAPEAL 347 E+ +QK EEE LE +R +L + ++ EL+ SW AP A+ Sbjct: 112 VEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAI 155 Score = 30.0 bits (66), Expect = 7.4 Identities = 29/143 (20%), Positives = 59/143 (41%), Gaps = 7/143 (4%) Query: 238 KEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLR---DEINLAK 294 +E + ++ + L R E +ERL +E + E K E+K + +E A Sbjct: 418 EEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAG 477 Query: 295 QEAQRLKE----LREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKW 350 +EA+R E L+E E E+ + E++ E R+ +++ + Q+ Sbjct: 478 EEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQER 537 Query: 351 LQLTHEVEVQYYNIKKQNAEKQL 373 L+ ++ +K + Q+ Sbjct: 538 LERKKRIDEIMKRTRKSDVPPQV 560 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.129 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,121,806 Number of Sequences: 37866 Number of extensions: 1385957 Number of successful extensions: 11884 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 267 Number of HSP's successfully gapped in prelim test: 775 Number of HSP's that attempted gapping in prelim test: 7482 Number of HSP's gapped (non-prelim): 3621 length of query: 685 length of database: 18,247,518 effective HSP length: 109 effective length of query: 576 effective length of database: 14,120,124 effective search space: 8133191424 effective search space used: 8133191424 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.