Guide to the Human Genome
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Search of human proteins with 21040261

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21040261 START domain containing protein 6 [Homo sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21040261 START domain containing protein 6 [Homo sapiens]          452   e-127
gi|32526915 StAR-related lipid transfer protein 5 [Homo sapiens]      142   2e-34
gi|21040247 StAR-related lipid transfer (START) domain containin...   112   3e-25
gi|31543657 StAR-related lipid transfer (START) domain containin...    78   5e-15
gi|56243551 steroidogenic acute regulatory protein isoform 1 [Ho...    78   7e-15
gi|56117848 steroidogenic acute regulatory protein isoform 2 [Ho...    56   3e-08
gi|151301035 START domain containing 7 [Homo sapiens]                  42   4e-04
gi|22165400 thioesterase, adipose associated isoform BFIT2 [Homo...    40   0.001
gi|22165355 thioesterase, adipose associated isoform BFIT1 [Homo...    40   0.001
gi|18640736 acyl-CoA thioesterase 12 [Homo sapiens]                    38   0.008
gi|116812600 START domain containing 10 [Homo sapiens]                 33   0.25 
gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo ...    28   8.0  
gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]                     28   8.0  
gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]                     28   8.0  
gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]                     28   8.0  
gi|30089954 H326 [Homo sapiens]                                        28   8.0  

>gi|21040261 START domain containing protein 6 [Homo sapiens]
          Length = 220

 Score =  452 bits (1162), Expect = e-127
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MDFKAIAQQTAQEVLGYNRDTSGWKVVKTSKKITVSSKASRKFHGNLYRVEGIIPESPAK 60
           MDFKAIAQQTAQEVLGYNRDTSGWKVVKTSKKITVSSKASRKFHGNLYRVEGIIPESPAK
Sbjct: 1   MDFKAIAQQTAQEVLGYNRDTSGWKVVKTSKKITVSSKASRKFHGNLYRVEGIIPESPAK 60

Query: 61  LSDFLYQTGDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRY 120
           LSDFLYQTGDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRY
Sbjct: 61  LSDFLYQTGDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRY 120

Query: 121 EGNMNIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLS 180
           EGNMNIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLS
Sbjct: 121 EGNMNIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLS 180

Query: 181 PSIIEKTMPSNLVNFILNAKDGIKAHRTPSRRGFHHNSHS 220
           PSIIEKTMPSNLVNFILNAKDGIKAHRTPSRRGFHHNSHS
Sbjct: 181 PSIIEKTMPSNLVNFILNAKDGIKAHRTPSRRGFHHNSHS 220


>gi|32526915 StAR-related lipid transfer protein 5 [Homo sapiens]
          Length = 213

 Score =  142 bits (358), Expect = 2e-34
 Identities = 68/201 (33%), Positives = 115/201 (57%), Gaps = 2/201 (0%)

Query: 6   IAQQTAQEVLGYNRDTSGWKVVKTSKKITVSSKASRKFHGNLYRVEGIIPESPAKLSDFL 65
           +++  A+++L Y RDT+GWK+ +    ++VS + S +F GNLYR EGI+  +  ++ D +
Sbjct: 9   MSEAVAEKMLQYRRDTAGWKICREGNGVSVSWRPSVEFPGNLYRGEGIVYGTLEEVWDCV 68

Query: 66  YQT--GDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRYEGN 123
                G R+ WD+++  + ++  I     +  T T S A+  ISPRDF+DLV +KRYE  
Sbjct: 69  KPAVGGLRVKWDENVTGFEIIQSITDTLCVSRTSTPSAAMKLISPRDFVDLVLVKRYEDG 128

Query: 124 MNIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLSPSI 183
               ++  V+ P  PP   ++RG+NHPCG  C P+   P  + LV F  T++ G L  ++
Sbjct: 129 TISSNATHVEHPLCPPKPGFVRGFNHPCGCFCEPLPGEPTKTNLVTFFHTDLSGYLPQNV 188

Query: 184 IEKTMPSNLVNFILNAKDGIK 204
           ++   P ++  F  N +  +K
Sbjct: 189 VDSFFPRSMTRFYANLQKAVK 209


>gi|21040247 StAR-related lipid transfer (START) domain containing 4
           [Homo sapiens]
          Length = 205

 Score =  112 bits (279), Expect = 3e-25
 Identities = 58/195 (29%), Positives = 103/195 (52%), Gaps = 4/195 (2%)

Query: 2   DFKAIAQQTAQEVLGYNR-DTSGWKVVKTSKKITVSSKASRKFHGNLYRVEGIIPESPAK 60
           D  + A +    ++ Y+  +   W+V K +K +TV  K S +F+G LY+ +G+I +    
Sbjct: 6   DVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYS 65

Query: 61  LSDFLYQTGDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRY 120
           + D +     R+ WD  +   +++   + +  +    T       ISPR+F+D  Y   Y
Sbjct: 66  IIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGY 125

Query: 121 EGNMNIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLS 180
           +  + +    S+D+ E  P   ++RGYNHPCG+ C P+++NP  S L  ++QT++RG + 
Sbjct: 126 KEGL-LSCGISLDWDEKRPE--FVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIP 182

Query: 181 PSIIEKTMPSNLVNF 195
            S ++  M S L NF
Sbjct: 183 QSAVDTAMASTLTNF 197


>gi|31543657 StAR-related lipid transfer (START) domain containing 3
           [Homo sapiens]
          Length = 445

 Score = 78.2 bits (191), Expect = 5e-15
 Identities = 44/182 (24%), Positives = 88/182 (48%), Gaps = 4/182 (2%)

Query: 24  WKVVKTSKKITVSSKASRKFHGNLYRVEGIIPESPAKL--SDFLYQTGDRITWDKSLQVY 81
           WK  K ++           FHG  + ++  +P  PA+L   + + Q    + W+K++   
Sbjct: 259 WKFEKNNEYGDTVYTIEVPFHGKTFILKTFLP-CPAELVYQEVILQPERMVLWNKTVTAC 317

Query: 82  NMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRYEGNMNIISSKSVDFPEYPPSS 141
            ++ R++ +T I + ++   A G +SPRDF+++  I+R      + S  +      PP+ 
Sbjct: 318 QILQRVEDNTLISYDVSAGAAGGVVSPRDFVNVRRIERRRDRY-LSSGIATSHSAKPPTH 376

Query: 142 NYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLSPSIIEKTMPSNLVNFILNAKD 201
            Y+RG N P GF+      NP     V  + T+++G+L   +I +++ + +  F  + + 
Sbjct: 377 KYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKGRLPRYLIHQSLAATMFEFAFHLRQ 436

Query: 202 GI 203
            I
Sbjct: 437 RI 438


>gi|56243551 steroidogenic acute regulatory protein isoform 1 [Homo
           sapiens]
          Length = 285

 Score = 77.8 bits (190), Expect = 7e-15
 Identities = 49/208 (23%), Positives = 100/208 (48%), Gaps = 6/208 (2%)

Query: 8   QQTAQEVLGYNRDTSGWKVVKTSKKITVSSKASRKFH--GNLYRVEGIIPESPAKLSDFL 65
           ++  Q+ LG   +  GWK  K S++       S+     G ++R+E ++ +   +L + L
Sbjct: 80  EEAMQKALGILSNQEGWK--KESQQDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEEL 137

Query: 66  YQTGDRI-TWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRYEGNM 124
            +  + +  W+ +++   ++ +I  DTFI H +    A   + PRDF+ +   KR  G+ 
Sbjct: 138 VERMEAMGEWNPNVKEIKVLQKIGKDTFITHELAAEAAGNLVGPRDFVSVRCAKR-RGST 196

Query: 125 NIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLSPSII 184
            +++  + DF   P     IR  + P   V  P+  +P+ +KL   +  +++G L  SII
Sbjct: 197 CVLAGMATDFGNMPEQKGVIRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKSII 256

Query: 185 EKTMPSNLVNFILNAKDGIKAHRTPSRR 212
            + +    V+F  + +  +++H     R
Sbjct: 257 NQVLSQTQVDFANHLRKRLESHPASEAR 284


>gi|56117848 steroidogenic acute regulatory protein isoform 2 [Homo
           sapiens]
          Length = 267

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 43/208 (20%), Positives = 92/208 (44%), Gaps = 24/208 (11%)

Query: 8   QQTAQEVLGYNRDTSGWKVVKTSKKITVSSKASRKFH--GNLYRVEGIIPESPAKLSDFL 65
           ++  Q+ LG   +  GWK  K S++       S+     G ++R+E ++ +   +L + L
Sbjct: 80  EEAMQKALGILSNQEGWK--KESQQDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEEL 137

Query: 66  YQTGDRI-TWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKRYEGNM 124
            +  + +  W+ +++   ++ +I                    PRDF+ +   KR  G+ 
Sbjct: 138 VERMEAMGEWNPNVKEIKVLQKIGG------------------PRDFVSVRCAKR-RGST 178

Query: 125 NIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMFVQTEMRGKLSPSII 184
            +++  + DF   P     IR  + P   V  P+  +P+ +KL   +  +++G L  SII
Sbjct: 179 CVLAGMATDFGNMPEQKGVIRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKSII 238

Query: 185 EKTMPSNLVNFILNAKDGIKAHRTPSRR 212
            + +    V+F  + +  +++H     R
Sbjct: 239 NQVLSQTQVDFANHLRKRLESHPASEAR 266


>gi|151301035 START domain containing 7 [Homo sapiens]
          Length = 370

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 15/150 (10%)

Query: 18  NRDTSG----WKVVKTSKKITVSSKASRKFHGNLYRVEGIIPE-SPAKLSDFLYQTGDRI 72
           N D+ G    W++V   K   +  +     H   YRV G   + +P +  +    T  R 
Sbjct: 131 NEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRK 190

Query: 73  TWDKSLQVYNMVHR-IDSDTFICHTITQSFAVGSISPRDFIDLVYIKRY----EGNMNII 127
            WD  +    ++ R + S + + H +T         P    D VY++RY    E NM ++
Sbjct: 191 KWDALVIKLEVIERDVVSGSEVLHWVTHF-----PYPMYSRDYVYVRRYSVDQENNMMVL 245

Query: 128 SSKSVDFPEYPPSSNYIRGYNHPCGFVCSP 157
            S++V+ P  P S  ++R  ++    V  P
Sbjct: 246 VSRAVEHPSVPESPEFVRVRSYESQMVIRP 275


>gi|22165400 thioesterase, adipose associated isoform BFIT2 [Homo
           sapiens]
          Length = 594

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 3/108 (2%)

Query: 48  YRVEGIIPESPAKLSDFLYQTGDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSIS 107
           + +E ++    A+    L     R  WDK  +   +V ++D D  I H +T     G   
Sbjct: 426 FHMEMVVHVDAAQAFLLLSDLRQRPEWDKHYRSVELVQQVDEDDAIYH-VTSPALGGHTK 484

Query: 108 PRDFIDLVYIKR--YEGNMNIISSKSVDFPEYPPSSNYIRGYNHPCGF 153
           P+DF+ L   ++    G+  +I+ +SV  P +  +  Y RG     GF
Sbjct: 485 PQDFVILASRRKPCDNGDPYVIALRSVTLPTHRETPEYRRGETLCSGF 532


>gi|22165355 thioesterase, adipose associated isoform BFIT1 [Homo
           sapiens]
          Length = 607

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 3/108 (2%)

Query: 48  YRVEGIIPESPAKLSDFLYQTGDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSIS 107
           + +E ++    A+    L     R  WDK  +   +V ++D D  I H +T     G   
Sbjct: 426 FHMEMVVHVDAAQAFLLLSDLRQRPEWDKHYRSVELVQQVDEDDAIYH-VTSPALGGHTK 484

Query: 108 PRDFIDLVYIKR--YEGNMNIISSKSVDFPEYPPSSNYIRGYNHPCGF 153
           P+DF+ L   ++    G+  +I+ +SV  P +  +  Y RG     GF
Sbjct: 485 PQDFVILASRRKPCDNGDPYVIALRSVTLPTHRETPEYRRGETLCSGF 532


>gi|18640736 acyl-CoA thioesterase 12 [Homo sapiens]
          Length = 555

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 37/142 (26%), Positives = 57/142 (40%), Gaps = 8/142 (5%)

Query: 23  GWKVVKTSKKITVSSKASRKFHGNLYRVEGIIPESPAKLS-DFLYQTGDRITWDKSLQVY 81
           GW+V  T +KI + +      H  L         SPA L+   L     R  WD      
Sbjct: 367 GWEVTSTVEKIKIYTLEE---HDVLSVWVEKHVGSPAHLAYRLLSDFTKRPLWDPHFVSC 423

Query: 82  NMVHRIDSDTFICHTITQSFAVGSISPRDFIDLVYIKR--YEGNMNIISSKSVDFPEYPP 139
            ++  +  D  + H       +    P+D + LV  ++   +GN   ++ KSV  P  PP
Sbjct: 424 EVIDWVSEDDQLYHITCP--ILNDDKPKDLVVLVSRRKPLKDGNTYTVAVKSVILPSVPP 481

Query: 140 SSNYIRGYNHPCGFVCSPMEEN 161
           S  YIR      GF+   ++ N
Sbjct: 482 SPQYIRSEIICAGFLIHAIDSN 503


>gi|116812600 START domain containing 10 [Homo sapiens]
          Length = 291

 Score = 32.7 bits (73), Expect = 0.25
 Identities = 44/197 (22%), Positives = 79/197 (40%), Gaps = 33/197 (16%)

Query: 2   DFKAIAQQTAQEVLGYNRDTSGWKVVKTSKKITVSSKA---SRKFHGNLYRVEGIIPESP 58
           DF++   +   EV        GW +  +   ++V  +A    R  H    R+E    + P
Sbjct: 29  DFRSFRSECEAEV--------GWNLTYSRAGVSVWVQAVEMDRTLHKIKCRMECC--DVP 78

Query: 59  AK-LSDFLYQTGDRITWDKSLQVYNMVHRIDSDTFICHTITQSFAVGSIS-----PRDFI 112
           A+ L D L+    R  WD ++           +TF    +T +  VG  S     P    
Sbjct: 79  AETLYDVLHDIEYRKKWDSNV----------IETFDIARLTVNADVGYYSWRCPKPLKNR 128

Query: 113 DLVYIKRY--EGNMNIISSKSVDFPEYPPSSNYIRGYNHPCGFVCSPMEENPAYSKLVMF 170
           D++ ++ +   G   II + SV  P+YPP  + +R  +   G++       P    +   
Sbjct: 129 DVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLI--QSTGPKSCVITYL 186

Query: 171 VQTEMRGKLSPSIIEKT 187
            Q + +G L   ++ K+
Sbjct: 187 AQVDPKGSLPKWVVNKS 203


>gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo
            sapiens]
          Length = 1246

 Score = 27.7 bits (60), Expect = 8.0
 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 6/64 (9%)

Query: 151  CGFVCSPMEENPAYSKLVMFVQTEMRGKLSPSIIEKTMPSN-LVNFILNAKDGIKAHRTP 209
            C + C P EE    +KL   V T ++   +P +  + + SN +++  +  K+GIK HRT 
Sbjct: 947  CIWYCIPAEEE---NKLEDVVHTLLQANGTPGL--QMLESNVMISPEVLCKEGIKVHRTV 1001

Query: 210  SRRG 213
             + G
Sbjct: 1002 QQSG 1005


>gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]
          Length = 1137

 Score = 27.7 bits (60), Expect = 8.0
 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 27  VKTSKKITVSSKASRKFHGNLYRVEGIIPESPAKLSDFLYQTGDRITWDKSLQVYNMVHR 86
           VKT   ++   KA  KFHG++Y  + +   SP  L + L +   R+ + K+     +VH 
Sbjct: 240 VKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSP--LREKLEEQFKRLLFQKAFNSQQLVHV 297

Query: 87  IDSDTFICH 95
              + F  H
Sbjct: 298 TVINLFQLH 306


>gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]
          Length = 1049

 Score = 27.7 bits (60), Expect = 8.0
 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 27  VKTSKKITVSSKASRKFHGNLYRVEGIIPESPAKLSDFLYQTGDRITWDKSLQVYNMVHR 86
           VKT   ++   KA  KFHG++Y  + +   SP  L + L +   R+ + K+     +VH 
Sbjct: 198 VKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSP--LREKLEEQFKRLLFQKAFNSQQLVHV 255

Query: 87  IDSDTFICH 95
              + F  H
Sbjct: 256 TVINLFQLH 264


>gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]
          Length = 1091

 Score = 27.7 bits (60), Expect = 8.0
 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 27  VKTSKKITVSSKASRKFHGNLYRVEGIIPESPAKLSDFLYQTGDRITWDKSLQVYNMVHR 86
           VKT   ++   KA  KFHG++Y  + +   SP  L + L +   R+ + K+     +VH 
Sbjct: 240 VKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSP--LREKLEEQFKRLLFQKAFNSQQLVHV 297

Query: 87  IDSDTFICH 95
              + F  H
Sbjct: 298 TVINLFQLH 306


>gi|30089954 H326 [Homo sapiens]
          Length = 597

 Score = 27.7 bits (60), Expect = 8.0
 Identities = 12/29 (41%), Positives = 19/29 (65%), Gaps = 2/29 (6%)

Query: 116 YIKRYEGNMNIISSKSVDFPEYPPSSNYI 144
           Y+KRY+G+ N  + K V+F  Y P S ++
Sbjct: 424 YVKRYKGHRNNATVKGVNF--YGPKSEFV 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,189,839
Number of Sequences: 37866
Number of extensions: 342313
Number of successful extensions: 653
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 642
Number of HSP's gapped (non-prelim): 16
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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