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Search of human proteins with 209862835
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
(211 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 419 e-117
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 419 e-117
gi|209915553 cyclin D3 isoform 3 [Homo sapiens] 307 4e-84
gi|4502617 cyclin D2 [Homo sapiens] 248 3e-66
gi|16950655 cyclin D1 [Homo sapiens] 201 4e-52
gi|209915556 cyclin D3 isoform 4 [Homo sapiens] 189 1e-48
gi|161377472 cyclin A1 isoform c [Homo sapiens] 73 2e-13
gi|161377470 cyclin A1 isoform c [Homo sapiens] 73 2e-13
gi|161377468 cyclin A1 isoform b [Homo sapiens] 73 2e-13
gi|4502611 cyclin A1 isoform a [Homo sapiens] 73 2e-13
gi|4502613 cyclin A [Homo sapiens] 69 3e-12
gi|4757930 cyclin B2 [Homo sapiens] 61 6e-10
gi|153791755 cyclin domain containing [Homo sapiens] 57 1e-08
gi|14327896 cyclin B1 [Homo sapiens] 56 3e-08
gi|197276674 cyclin J isoform 1 [Homo sapiens] 54 1e-07
gi|17318565 cyclin E2 [Homo sapiens] 48 5e-06
gi|40805832 cyclin G1 [Homo sapiens] 44 1e-04
gi|4757934 cyclin G1 [Homo sapiens] 44 1e-04
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 40 0.001
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 40 0.001
gi|40254889 cyclin J isoform 2 [Homo sapiens] 39 0.002
gi|94680985 cyclin J-like [Homo sapiens] 39 0.002
gi|197276676 cyclin J isoform 3 [Homo sapiens] 38 0.005
gi|4757936 cyclin G2 [Homo sapiens] 37 0.009
gi|38524591 intramembrane protease 5 [Homo sapiens] 37 0.009
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 37 0.012
gi|5802992 cyclin I [Homo sapiens] 35 0.047
gi|89886237 cyclin I family, member 2 [Homo sapiens] 34 0.079
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 32 0.51
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 32 0.51
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 419 bits (1076), Expect = e-117
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE
Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS
Sbjct: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
Query: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 180
MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT
Sbjct: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 180
Query: 181 SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211
SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Sbjct: 181 SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 419 bits (1076), Expect = e-117
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE
Sbjct: 82 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 141
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS
Sbjct: 142 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 201
Query: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 180
MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT
Sbjct: 202 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 261
Query: 181 SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211
SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Sbjct: 262 SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292
>gi|209915553 cyclin D3 isoform 3 [Homo sapiens]
Length = 220
Score = 307 bits (787), Expect = 4e-84
Identities = 155/156 (99%), Positives = 155/156 (99%)
Query: 56 LRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFA 115
L DWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFA
Sbjct: 65 LEDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFA 124
Query: 116 MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR 175
MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR
Sbjct: 125 MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR 184
Query: 176 EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211
EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Sbjct: 185 EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 220
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 248 bits (633), Expect = 3e-66
Identities = 130/216 (60%), Positives = 162/216 (75%), Gaps = 12/216 (5%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
MNYLDR+L+ VPT K+ LQLLGAVCM LASKL+ET+PLT EKLCIYTD+++ P++L +WE
Sbjct: 81 MNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWE 140
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
++VLGKLKW+LAAV HDF+ IL +L R++ +L++KHAQTF+ALCATD+ FAMYPPS
Sbjct: 141 LVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPS 200
Query: 121 MIATGSIGAAVQGL----GACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLRE 176
MIATGS+GAA+ GL S++ D LTELLA IT T+VDCL+ACQEQIEA L SL++
Sbjct: 201 MIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQ 260
Query: 177 ASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL 211
Q GS S+ Q STPTDV I L
Sbjct: 261 YRQDQRD-------GSKSEDELDQASTPTDVRDIDL 289
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 201 bits (511), Expect = 4e-52
Identities = 104/215 (48%), Positives = 140/215 (65%), Gaps = 5/215 (2%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
MNYLDR+LS P +K++LQLLGA CM +ASK++ET PLT EKLCIYTD+++ P +L E
Sbjct: 82 MNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQME 141
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
+L++ KLKW+LAA+ HDF+ L ++ + + +++KHAQTF+ALCATD F PPS
Sbjct: 142 LLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPS 201
Query: 121 MIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEVDCLRACQEQIEAALRESLRE 176
M+A GS+ AAVQGL S +S LT L+ + + DCLRACQEQIEA L SLR+
Sbjct: 202 MVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQ 261
Query: 177 ASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211
A Q + P + TPTDV + +
Sbjct: 262 AQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295
>gi|209915556 cyclin D3 isoform 4 [Homo sapiens]
Length = 96
Score = 189 bits (481), Expect = 1e-48
Identities = 96/96 (100%), Positives = 96/96 (100%)
Query: 116 MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR 175
MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR
Sbjct: 1 MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR 60
Query: 176 EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211
EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Sbjct: 61 EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 96
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 72.8 bits (177), Expect = 2e-13
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 8/169 (4%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
+N+LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E
Sbjct: 225 VNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKME 284
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
L+L L +DL + FL L R + + L K A+ L+L D F Y PS
Sbjct: 285 HLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPS 341
Query: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 169
+IA AA L +++ E LA TG + + C ++ A
Sbjct: 342 LIA-----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 385
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 72.8 bits (177), Expect = 2e-13
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 8/169 (4%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
+N+LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E
Sbjct: 225 VNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKME 284
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
L+L L +DL + FL L R + + L K A+ L+L D F Y PS
Sbjct: 285 HLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPS 341
Query: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 169
+IA AA L +++ E LA TG + + C ++ A
Sbjct: 342 LIA-----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 385
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 72.8 bits (177), Expect = 2e-13
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 8/169 (4%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
+N+LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E
Sbjct: 268 VNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKME 327
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
L+L L +DL + FL L R + + L K A+ L+L D F Y PS
Sbjct: 328 HLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPS 384
Query: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 169
+IA AA L +++ E LA TG + + C ++ A
Sbjct: 385 LIA-----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 428
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 72.8 bits (177), Expect = 2e-13
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 8/169 (4%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
+N+LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E
Sbjct: 269 VNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKME 328
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
L+L L +DL + FL L R + + L K A+ L+L D F Y PS
Sbjct: 329 HLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPS 385
Query: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 169
+IA AA L +++ E LA TG + + C ++ A
Sbjct: 386 LIA-----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 429
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 68.9 bits (167), Expect = 3e-12
Identities = 56/181 (30%), Positives = 89/181 (49%), Gaps = 9/181 (4%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
+NY+DR+LS + + +LQL+G MLLASK E P + + TD + +Q+ E
Sbjct: 236 VNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME 295
Query: 61 VLVLGKLKWDLAAVIAHDFLA-FILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPP 119
LVL L +DLAA + FL + LH+ ++L + L+L D + Y P
Sbjct: 296 HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLP 352
Query: 120 SMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQ 179
S+IA GAA L +++G E L TG ++ L+ C + ++ + A Q
Sbjct: 353 SVIA----GAAFH-LALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQ 407
Query: 180 T 180
+
Sbjct: 408 S 408
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 61.2 bits (147), Expect = 6e-10
Identities = 41/132 (31%), Positives = 63/132 (47%), Gaps = 4/132 (3%)
Query: 4 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 63
+DR+L P + +LQL+G +LLASK E IE TD+A + Q+R+ E L+
Sbjct: 194 MDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLI 253
Query: 64 LGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 123
L +LK++L + F L R S + A+ + L DY Y PS +A
Sbjct: 254 LKELKFELGRPLPLHF----LRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVA 309
Query: 124 TGSIGAAVQGLG 135
+ + + LG
Sbjct: 310 AAASCLSQKVLG 321
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 57.0 bits (136), Expect = 1e-08
Identities = 44/131 (33%), Positives = 61/131 (46%), Gaps = 12/131 (9%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
+N LDR+L+ P QLLG +L+A K E P +++L A S +QL + E
Sbjct: 158 VNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLE 217
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILH--------RLSLPRDRQALVKKHAQTFLALCATDY 112
+VL KL + L A FL H S + QAL + A+ LA DY
Sbjct: 218 CIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLA----DY 273
Query: 113 TFAMYPPSMIA 123
F Y PS++A
Sbjct: 274 AFTSYSPSLLA 284
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 55.8 bits (133), Expect = 3e-08
Identities = 42/136 (30%), Positives = 67/136 (49%), Gaps = 12/136 (8%)
Query: 1 MNYLDRYL--SCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRD 58
++ +DR++ +CVP K LQL+G M +ASK E P I TD+ + Q+R
Sbjct: 227 VSIIDRFMQNNCVP--KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQ 284
Query: 59 WEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKH--AQTFLALCATDYTFAM 116
E+ +L L + L + F L R S + + V++H A+ + L DY
Sbjct: 285 MEMKILRALNFGLGRPLPLHF----LRRAS--KIGEVDVEQHTLAKYLMELTMLDYDMVH 338
Query: 117 YPPSMIATGSIGAAVQ 132
+PPS IA G+ A++
Sbjct: 339 FPPSQIAAGAFCLALK 354
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 53.5 bits (127), Expect = 1e-07
Identities = 58/220 (26%), Positives = 94/220 (42%), Gaps = 27/220 (12%)
Query: 3 YLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVSPRQ- 55
++DRY + QL L+ C+LLASK +E + +E+L C+ + V +Q
Sbjct: 71 FMDRYDISIQ----QLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQN 126
Query: 56 LRDWEVLVLGKLKWDLAAVIAHDFLAFIL----HRLSLP--------RDRQALVKKHAQT 103
L E+L+L +W+L A F+ + L H L + + K+A
Sbjct: 127 LLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADY 186
Query: 104 FLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQ 163
FL + DY F Y PS++A + ++ L L L T D L C
Sbjct: 187 FLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRL----TAYSWDFLVQCI 242
Query: 164 EQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 203
E++ A ++EA++ P++ + S Q SQ S P
Sbjct: 243 ERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 282
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 48.1 bits (113), Expect = 5e-06
Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Query: 2 NYLDRY-LSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
++ DR+ L+ K LQL+G + +ASKL E +++ TD A S + E
Sbjct: 168 DFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRME 227
Query: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQ-TFLALCATDYTFAMYPP 119
+++L LKW+L V +L L +L + L+ +++Q TF+ + +
Sbjct: 228 LIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIA------QLLDL 281
Query: 120 SMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRAC 162
++A S+ + L A ++ E++ +G E D + C
Sbjct: 282 CILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISEC 324
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 43.9 bits (102), Expect = 1e-04
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDHAVSPRQLR 57
+N LDR+LS + + L +G C LA K E PL + + I + + + L
Sbjct: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135
Query: 58 DWEVLVLGKLKWDLAAVIAHDFLA--FILHRLSLPRDRQALVK-KHAQTFLALCATDYTF 114
E +VL K+ W + A A FL + L + +LP +R+ + + + L C F
Sbjct: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIF 195
Query: 115 AMYPPSMIATGSIGAAVQGLGACSMS-GDELTELLAGITGTEVDCLRACQEQIEAALRE 172
+ PS++A I +Q ++ G E + + I G + L QE + L E
Sbjct: 196 SKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRD---LTFWQELVSKCLTE 251
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 43.9 bits (102), Expect = 1e-04
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDHAVSPRQLR 57
+N LDR+LS + + L +G C LA K E PL + + I + + + L
Sbjct: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135
Query: 58 DWEVLVLGKLKWDLAAVIAHDFLA--FILHRLSLPRDRQALVK-KHAQTFLALCATDYTF 114
E +VL K+ W + A A FL + L + +LP +R+ + + + L C F
Sbjct: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIF 195
Query: 115 AMYPPSMIATGSIGAAVQGLGACSMS-GDELTELLAGITGTEVDCLRACQEQIEAALRE 172
+ PS++A I +Q ++ G E + + I G + L QE + L E
Sbjct: 196 SKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRD---LTFWQELVSKCLTE 251
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 40.0 bits (92), Expect = 0.001
Identities = 23/77 (29%), Positives = 37/77 (48%)
Query: 4 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 63
+D YL +K +LQLLGA ++A+K E ++ D ++ E+ +
Sbjct: 85 VDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINI 144
Query: 64 LGKLKWDLAAVIAHDFL 80
L LK D+ IA+ FL
Sbjct: 145 LNVLKCDINIPIAYHFL 161
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 40.0 bits (92), Expect = 0.001
Identities = 23/77 (29%), Positives = 37/77 (48%)
Query: 4 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 63
+D YL +K +LQLLGA ++A+K E ++ D ++ E+ +
Sbjct: 1189 VDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINI 1248
Query: 64 LGKLKWDLAAVIAHDFL 80
L LK D+ IA+ FL
Sbjct: 1249 LNVLKCDINIPIAYHFL 1265
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 39.3 bits (90), Expect = 0.002
Identities = 54/215 (25%), Positives = 87/215 (40%), Gaps = 28/215 (13%)
Query: 3 YLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVSPRQ- 55
++DRY + QL L+ C+LLASK +E + +E+L C+ + V +Q
Sbjct: 71 FMDRYDISIQ----QLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQN 126
Query: 56 LRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFA 115
L E+L+L +W+L A F+ + L D + L T A
Sbjct: 127 LLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLH-----DGWPMICLEKTKLYMA 181
Query: 116 MYPPSMIATGSIGAAVQGLGACSMSGDELTEL-------LAGITGTEVDCLRACQEQIEA 168
Y A + ++Q AC S + L L +T D L C E++
Sbjct: 182 KY-----ADYFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLI 236
Query: 169 ALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 203
A ++EA++ P++ + S Q SQ S P
Sbjct: 237 AHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 271
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 39.3 bits (90), Expect = 0.002
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 17/152 (11%)
Query: 51 VSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFIL--------HRL-----SLPRDRQALV 97
++ ++L E+L+L W+L FL + L H + PR + +
Sbjct: 170 LTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECL 229
Query: 98 KKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVD 157
K++A FL + D+ F + PS++A +GA+ C T L I+ ++
Sbjct: 230 KEYAHYFLEVTLQDHIFYKFQPSVVAAACVGAS----RICLQLSPYWTRDLQRISSYSLE 285
Query: 158 CLRACQEQIEAALRESLREASQTSSSPAPKAP 189
L C E + L++A S P
Sbjct: 286 HLSTCIEILLVVYDNVLKDAVAVKSQALAMVP 317
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 38.1 bits (87), Expect = 0.005
Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 37/219 (16%)
Query: 3 YLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVSPRQ- 55
++DRY + QL L+ C+LLASK +E + +E+L C+ + V +Q
Sbjct: 71 FMDRYDISIQ----QLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQN 126
Query: 56 LRDWEVLVLGKLKWDLAAVIAHDFLAFIL----HRLSLPRDRQALVKKHAQTFLALCATD 111
L E+L+L +W+L A F+ + L H L + + + ++A A D
Sbjct: 127 LLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYA-D 185
Query: 112 YTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTEL-------LAGITGTEVDCLRACQE 164
Y + S+ AA AC S + L L +T D L C E
Sbjct: 186 YFLEV---------SLQAA-----ACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIE 231
Query: 165 QIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 203
++ A ++EA++ P++ + S Q SQ S P
Sbjct: 232 RLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 270
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 37.4 bits (85), Expect = 0.009
Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 15/155 (9%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDHAVSPRQLR 57
+N LDR+L+ + + L +G LLA+++ E P T + + I + + ++
Sbjct: 81 VNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRI-SQCKCTASDIK 139
Query: 58 DWEVLVLGKLKWDLAAVIAHDFL----AFILHRLSLPRDRQALVKKHAQTFLALCATDYT 113
E ++ KL ++L A A +FL IL S ++ +L K AQ L C
Sbjct: 140 RMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEILSLDKLEAQ--LKACNCRLI 197
Query: 114 FAMYPPSMIATGSIGAAVQGLGACSMSGDELTELL 148
F+ PS++A + V+ ++ EL E+L
Sbjct: 198 FSKAKPSVLALCLLNLEVE-----TLKSVELLEIL 227
>gi|38524591 intramembrane protease 5 [Homo sapiens]
Length = 684
Score = 37.4 bits (85), Expect = 0.009
Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 5/96 (5%)
Query: 69 WDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIG 128
W L + + F+LHR+ LP +K + LAL A D F P TG
Sbjct: 349 WLLQDTLGISYCLFVLHRVRLPT-----LKNCSSFLLALLAFDVFFVFVTPFFTKTGESI 403
Query: 129 AAVQGLGACSMSGDELTELLAGITGTEVDCLRACQE 164
A LG S E ++ + V L C +
Sbjct: 404 MAQVALGPAESSSHERLPMVLKVPRLRVSALTLCSQ 439
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 37.0 bits (84), Expect = 0.012
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
++ LD YLS R +LQLLG C+ +A K+ E LC+ + + S +L E
Sbjct: 133 VHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAE 192
Query: 61 VLVLGKLKWDL 71
+L +L + L
Sbjct: 193 RRILSRLDFRL 203
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 35.0 bits (79), Expect = 0.047
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 4 LDRYLSCVPTRKAQLQLLGAVCMLLASK-LRETTPLTIEKLCIYTDHA-VSPRQLRDWEV 61
LDR+L+ V L + C LA+K + E + + K+ S ++ E
Sbjct: 73 LDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMER 132
Query: 62 LVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL 96
++L KL WDL DFL I H +++ Q L
Sbjct: 133 IILDKLNWDLHTATPLDFL-HIFHAIAVSTRPQLL 166
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 34.3 bits (77), Expect = 0.079
Identities = 49/195 (25%), Positives = 81/195 (41%), Gaps = 21/195 (10%)
Query: 6 RYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHA---VSPRQLRDWEVL 62
R L V ++ L + LA+K+ E I ++ +T H SP +L E+
Sbjct: 180 RLLISVKVKEKYLHCATITSLRLAAKVNEEEEF-IPQVKDFTKHYGSDYSPNELLRMELA 238
Query: 63 VLGKLKWDLAAVIAHDFLAFI--LHRLSLPRDRQALVKKHAQTFLAL-------CATDYT 113
+L +L WDL DFL L LS P + L +++ +A C +
Sbjct: 239 ILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQLQHCMAGHQ 298
Query: 114 FAMYPPSMIATGSIGAAVQGL--GACSMSGDELTELLAGITGTEVDCLRACQEQIEAALR 171
+ S +A I ++ L G C+ D L + A + + C C+E + LR
Sbjct: 299 LLQFKGSTLALVIITLELERLMPGWCAPISDLLKK--AQVGDMQYSC---CKELVMQQLR 353
Query: 172 ESLREASQTSSSPAP 186
SL+ +S T + +P
Sbjct: 354 -SLQSSSCTDNFVSP 367
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 31.6 bits (70), Expect = 0.51
Identities = 18/49 (36%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 163 QEQIEAALR-ESLREASQTSSSPAPKAPRGSSSQGPSQ-TSTPTDVTAI 209
Q Q++A ++ +++ ++ T+SSPAP +SS PS TST T T++
Sbjct: 244 QAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 31.6 bits (70), Expect = 0.51
Identities = 18/49 (36%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 163 QEQIEAALR-ESLREASQTSSSPAPKAPRGSSSQGPSQ-TSTPTDVTAI 209
Q Q++A ++ +++ ++ T+SSPAP +SS PS TST T T++
Sbjct: 244 QAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.131 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,923,981
Number of Sequences: 37866
Number of extensions: 316706
Number of successful extensions: 2113
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2025
Number of HSP's gapped (non-prelim): 110
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.