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Search of human proteins with 20143482
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
(957 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 1931 0.0
gi|20162570 melanoma antigen family E, 2 [Homo sapiens] 367 e-101
gi|29826296 melanoma antigen family F, 1 [Homo sapiens] 227 5e-59
gi|20162572 necdin-like 2 [Homo sapiens] 221 2e-57
gi|148746206 MAGE-like protein 2 [Homo sapiens] 219 7e-57
gi|29171705 melanoma antigen family D, 2 [Homo sapiens] 203 5e-52
gi|19387846 melanoma antigen family D, 2 [Homo sapiens] 203 5e-52
gi|41350320 melanoma antigen family D, 2 [Homo sapiens] 203 5e-52
gi|29540551 trophinin isoform 2 [Homo sapiens] 194 3e-49
gi|29540541 trophinin isoform 2 [Homo sapiens] 194 3e-49
gi|89276766 trophinin isoform 5 [Homo sapiens] 191 4e-48
gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens] 190 6e-48
gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens] 188 2e-47
gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens] 188 2e-47
gi|153791873 melanoma antigen family B, 16 [Homo sapiens] 188 2e-47
gi|4505085 melanoma antigen family B, 4 [Homo sapiens] 181 3e-45
gi|27734781 melanoma antigen family B, 18 [Homo sapiens] 181 3e-45
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 179 1e-44
gi|73623441 melanoma antigen family B, 10 [Homo sapiens] 177 4e-44
gi|58530863 melanoma antigen family A, 10 [Homo sapiens] 176 1e-43
gi|10567820 melanoma antigen family A, 10 [Homo sapiens] 176 1e-43
gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens] 173 6e-43
gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens] 173 6e-43
gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens] 173 6e-43
gi|149274614 melanoma antigen family D, 4 [Homo sapiens] 173 6e-43
gi|222418639 melanoma antigen family B, 2 [Homo sapiens] 172 1e-42
gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo sapi... 172 1e-42
gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo sapi... 172 1e-42
gi|169216802 PREDICTED: melanoma antigen family B, 17 [Homo sapi... 172 1e-42
gi|29171711 melanoma antigen family B, 1 [Homo sapiens] 169 9e-42
>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
Length = 957
Score = 1931 bits (5002), Expect = 0.0
Identities = 957/957 (100%), Positives = 957/957 (100%)
Query: 1 MSLVSQNSRRRRRRVAKATAHNSSWGEMQAPNAPGLPADVPGSDVPQGPSDSQILQGLCA 60
MSLVSQNSRRRRRRVAKATAHNSSWGEMQAPNAPGLPADVPGSDVPQGPSDSQILQGLCA
Sbjct: 1 MSLVSQNSRRRRRRVAKATAHNSSWGEMQAPNAPGLPADVPGSDVPQGPSDSQILQGLCA 60
Query: 61 SEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTI 120
SEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTI
Sbjct: 61 SEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTI 120
Query: 121 SKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTA 180
SKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTA
Sbjct: 121 SKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTA 180
Query: 181 YEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTA 240
YEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTA
Sbjct: 181 YEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTA 240
Query: 241 TEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTA 300
TEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTA
Sbjct: 241 TEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTA 300
Query: 301 TEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIP 360
TEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIP
Sbjct: 301 TEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIP 360
Query: 361 GEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSA 420
GEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSA
Sbjct: 361 GEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSA 420
Query: 421 SVDRNPSKCSLVLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSR 480
SVDRNPSKCSLVLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSR
Sbjct: 421 SVDRNPSKCSLVLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSR 480
Query: 481 VAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHL 540
VAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHL
Sbjct: 481 VAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHL 540
Query: 541 ECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKE 600
ECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKE
Sbjct: 541 ECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKE 600
Query: 601 AEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSH 660
AEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSH
Sbjct: 601 AEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSH 660
Query: 661 LETTKMKILKFMAKIYNKDPMDWPEKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAE 720
LETTKMKILKFMAKIYNKDPMDWPEKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAE
Sbjct: 661 LETTKMKILKFMAKIYNKDPMDWPEKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAE 720
Query: 721 VPSPDSEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECS 780
VPSPDSEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECS
Sbjct: 721 VPSPDSEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECS 780
Query: 781 KVFPDLLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQ 840
KVFPDLLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQ
Sbjct: 781 KVFPDLLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQ 840
Query: 841 VLSFIFIMGNHARESAVWAFLRGLGVQAGRKHVITCRYLSQRYIDSLRVPDSDPVQYEFV 900
VLSFIFIMGNHARESAVWAFLRGLGVQAGRKHVITCRYLSQRYIDSLRVPDSDPVQYEFV
Sbjct: 841 VLSFIFIMGNHARESAVWAFLRGLGVQAGRKHVITCRYLSQRYIDSLRVPDSDPVQYEFV 900
Query: 901 WGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRADVGHRQIFVHNFR 957
WGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRADVGHRQIFVHNFR
Sbjct: 901 WGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRADVGHRQIFVHNFR 957
>gi|20162570 melanoma antigen family E, 2 [Homo sapiens]
Length = 523
Score = 367 bits (943), Expect = e-101
Identities = 195/502 (38%), Positives = 296/502 (58%), Gaps = 38/502 (7%)
Query: 448 EGPKGAEGPIEFEVLRDCES---PNSISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLV 504
+ P+ + PI + + ++ PN + ++ SR L+ DP+E L+ F+ +
Sbjct: 42 DAPQCPQAPINSQCVNTSQAVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRM 101
Query: 505 KDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELDPEAHTYILLNKL 564
K Q++ I++SEM E++ +EY +QFPEILRRA+AHL+ +F LR +DP+A TY L++K
Sbjct: 102 KSQTEGSIQQSEMLEFL-REYSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKR 160
Query: 565 GPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGV--QRERRLSIFG 622
G + + ES + PK LL ++LG I LNGN+A+EA IW++L ++ + + +R ++FG
Sbjct: 161 GFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFG 220
Query: 623 NPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMD 682
N + LL+ +FV R+L+Y PV P+E+EF WG R+H E TKM+ LKF++ ++++P
Sbjct: 221 NTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWS 280
Query: 683 WPEKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPE 742
WPE+YN+ALE D + S W E
Sbjct: 281 WPEEYNKALEGDKTK--------------------------------ERSLTAGLEFWSE 308
Query: 743 SRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTEL 802
+ KA LVQL + + LPI + +L + G+E VFP++LNRA L+ YG L
Sbjct: 309 DTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSL 368
Query: 803 VVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLR 862
+ +D H Y L + E EE + +++S RP ++M +L IF+MGN +E+ VW LR
Sbjct: 369 IEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLR 428
Query: 863 GLGVQAGRKHVITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALRYVARIH 922
V GRKH IT + + QRY++ + S+PV+YE +WGPRA ET KMK L Y+AR++
Sbjct: 429 RFSVDVGRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLEYMARLY 488
Query: 923 RKEPQDWPQQYREAMEDEANRA 944
RK PQ+WP+QYREA+EDE RA
Sbjct: 489 RKRPQNWPEQYREAVEDEEARA 510
Score = 156 bits (395), Expect = 8e-38
Identities = 81/214 (37%), Positives = 123/214 (57%), Gaps = 8/214 (3%)
Query: 488 QDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFE 547
+D M +L+Q + + PI + E+ + KE+ + FP IL RA L+ +
Sbjct: 308 EDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLS 367
Query: 548 LRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEML 607
L E+D H Y+L+ + + + ES P +M ILG IFL GN+ KEA +W +L
Sbjct: 368 LIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLL 427
Query: 608 WRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMK 667
RR S+ K ++ + + QRYL+ RP++ PVEYE WGPR+H ET KMK
Sbjct: 428 --------RRFSVDVGRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMK 479
Query: 668 ILKFMAKIYNKDPMDWPEKYNEALEEDAARAFAE 701
+L++MA++Y K P +WPE+Y EA+E++ ARA +E
Sbjct: 480 VLEYMARLYRKRPQNWPEQYREAVEDEEARAKSE 513
Score = 34.7 bits (78), Expect = 0.44
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query: 1 MSLVSQNSRRRRRRVAKATAHNSSWGEMQAPNAPGLPAD---VPGSDVPQGPSDSQILQG 57
MSLVSQN+R + + GE+QA NA G P V PQ P +SQ +
Sbjct: 1 MSLVSQNARHCSAEIT--ADYGDGRGEIQATNASGSPTSMLVVDAPQCPQAPINSQCVNT 58
Query: 58 LCASEGPS 65
A + P+
Sbjct: 59 SQAVQDPN 66
>gi|29826296 melanoma antigen family F, 1 [Homo sapiens]
Length = 307
Score = 227 bits (578), Expect = 5e-59
Identities = 111/212 (52%), Positives = 154/212 (72%), Gaps = 1/212 (0%)
Query: 491 MEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRE 550
+ + VAEL+QFLLVKD+ K PI SEM +Y++ + + FP+I+ RAA HL +F FEL++
Sbjct: 76 LNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQ 135
Query: 551 LDPEAHTYILLNKLGPVPFEGLEE-SPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWR 609
D + HTYIL+NKL P+ E E+ +GP++GLLMMILG I++ GN A+EA++WEML R
Sbjct: 136 FDRKHHTYILINKLKPLEEEEEEDLGGDGPRLGLLMMILGLIYMRGNSAREAQVWEMLRR 195
Query: 610 MGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKIL 669
+GVQ + +FG PKRL+ +FV QRYL YR V P EYEF WGPRS+LE +KM++L
Sbjct: 196 LGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPEYEFSWGPRSNLEISKMEVL 255
Query: 670 KFMAKIYNKDPMDWPEKYNEALEEDAARAFAE 701
F+AK++ K+P WP +Y EAL ++A RA A+
Sbjct: 256 GFVAKLHKKEPQHWPVQYREALADEADRARAK 287
Score = 174 bits (440), Expect = 5e-43
Identities = 96/239 (40%), Positives = 138/239 (57%), Gaps = 9/239 (3%)
Query: 715 EEAAAEVPSPDSEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYY 774
EE AAE + ++K RL +LVQ L+ D K PI + ++ Y
Sbjct: 46 EEGAAEPALTRKGARALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKY 105
Query: 775 IGRECSKVFPDLLNRAARTLNHVYGTELVVLDPRNHSYTLYNR-REMEETEEIVDSPNRP 833
+ + +FPD++ RAA L +V+G EL D ++H+Y L N+ + +EE EE + P
Sbjct: 106 VIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEEDLGGDGP 165
Query: 834 GNNFLMQVLSFIFIMGNHARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYID 885
LM +L I++ GN ARE+ VW LR LGVQ + H +I ++ QRY+
Sbjct: 166 RLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLS 225
Query: 886 SLRVPDSDPVQYEFVWGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
RVP ++P +YEF WGPR+ LE SKM+ L +VA++H+KEPQ WP QYREA+ DEA+RA
Sbjct: 226 YRRVPHTNPPEYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEADRA 284
>gi|20162572 necdin-like 2 [Homo sapiens]
Length = 304
Score = 221 bits (564), Expect = 2e-57
Identities = 112/257 (43%), Positives = 172/257 (66%), Gaps = 15/257 (5%)
Query: 445 SDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLKP--QDPMEQNVAELLQFL 502
S S GP G++G + P S G ++ A + P Q +E V+EL+QFL
Sbjct: 49 STSRGPGGSQGS---------QGP---SPQGARRAQAAPAVGPRSQKQLELKVSELVQFL 96
Query: 503 LVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELDPEAHTYILLN 562
L+KDQ K PI+ +++ ++++ +Y++ FP++ +RAA L+ +F ++L EL+P+++TYIL+N
Sbjct: 97 LIKDQKKIPIKRADILKHVIGDYKDIFPDLFKRAAERLQYVFGYKLVELEPKSNTYILIN 156
Query: 563 KLGPVPFEGLEESPNG-PKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIF 621
L PV + G P GLLM++LG IF+ GN KE E W+ L R+GV ++ IF
Sbjct: 157 TLEPVEEDAEMRGDQGTPTTGLLMIVLGLIFMKGNTIKETEAWDFLRRLGVYPTKKHLIF 216
Query: 622 GNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPM 681
G+PK+L++ +FV QRYL+YR + PV+YEF WGPR++LET+KMK+LKF+AK++N+DP
Sbjct: 217 GDPKKLITEDFVRQRYLEYRRIPHTDPVDYEFQWGPRTNLETSKMKVLKFVAKVHNQDPK 276
Query: 682 DWPEKYNEALEEDAARA 698
DWP +Y EAL ++ RA
Sbjct: 277 DWPAQYCEALADEENRA 293
Score = 187 bits (476), Expect = 3e-47
Identities = 109/277 (39%), Positives = 156/277 (56%), Gaps = 17/277 (6%)
Query: 682 DWPEKYNEALEE--DAARAFAEGW-QALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPH 738
DW N + AR +G+ + P R ++ PSP + ++ AP
Sbjct: 20 DWSHSGNPGASRAGEDARVLRDGFAEEAPSTSRGPGGSQGSQGPSPQG---ARRAQAAPA 76
Query: 739 SWPESR--LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNH 796
P S+ LE K +LVQ L+ D K+PI + IL ++ + +FPDL RAA L +
Sbjct: 77 VGPRSQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIGDYKDIFPDLFKRAAERLQY 136
Query: 797 VYGTELVVLDPRNHSYTLYNRRE-MEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARES 855
V+G +LV L+P++++Y L N E +EE E+ P LM VL IF+ GN +E+
Sbjct: 137 VFGYKLVELEPKSNTYILINTLEPVEEDAEMRGDQGTPTTGLLMIVLGLIFMKGNTIKET 196
Query: 856 AVWAFLRGLGVQAGRKHVI--------TCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARL 907
W FLR LGV +KH+I T ++ QRY++ R+P +DPV YEF WGPR L
Sbjct: 197 EAWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTDPVDYEFQWGPRTNL 256
Query: 908 ETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
ETSKMK L++VA++H ++P+DWP QY EA+ DE NRA
Sbjct: 257 ETSKMKVLKFVAKVHNQDPKDWPAQYCEALADEENRA 293
>gi|148746206 MAGE-like protein 2 [Homo sapiens]
Length = 646
Score = 219 bits (559), Expect = 7e-57
Identities = 186/632 (29%), Positives = 279/632 (44%), Gaps = 107/632 (16%)
Query: 130 LAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGT-------------STSV 176
L A E + + P E+P PP+ V LPP + + S
Sbjct: 27 LPAQEAQRQAPPLVQLEQPFQGAPPSQKAV-QIQLPPQQAQASGPQAEVPTLPLQPSWQA 85
Query: 177 PPT---AYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEG---LSTSVQATPDE 230
PP A GP + P G + S++ GE +S+ + S+ + P +
Sbjct: 86 PPAVLQAQPGPPVAAANFP-LGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERRAPSK 144
Query: 231 G----PSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGE-GPSTSVLPAASDGQSISLV 285
+T P A +P ++PATP PS+SV PA S Q SL
Sbjct: 145 DRMIFAATFCAPKAVSAARAHLPAAWK-----NLPATPETFAPSSSVFPATSQFQPASLN 199
Query: 286 PTRGKGSSTSVP---PTATEGLSTSVQ--------PTAGEGSSTSVPPTPGGGLSTSVPP 334
+G +++ P P A + V+ P +S + P ++T+ P
Sbjct: 200 AFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAP 259
Query: 335 TAT----EELSTSVPPTPGEGPSTSVL---------------------PIPGEGLSTS-- 367
AT E TSV P G +T P P E L+ S
Sbjct: 260 QATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHTLAFHDWQGPRPWENLNLSDW 319
Query: 368 -VPPTASDGSDTSVPPTPG-----EGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSAS 421
V D P TP EG ST + +GP +S + EGPST S +
Sbjct: 320 EVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAWEGPST--SRALG 377
Query: 422 VDRNPSKCSLVLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRV 481
+ +P LP V + V S S G + + E
Sbjct: 378 LSESPGSS---LP---VVVSEVASVSPGSSATQDNSKVEA-------------------- 411
Query: 482 AITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLE 541
+P P+++ L+QFLLVKDQ+K P++ SEM + I++EY+++ +I+ RA LE
Sbjct: 412 ----QPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLE 467
Query: 542 CIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEA 601
C F ++L+E+D + H YI++NKLG + + PK GLLM++L IF+ GN +E
Sbjct: 468 CAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVRED 527
Query: 602 EIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHL 661
I+ L+++G+ +FGN K+L++ FV Q+YL+YR + +P EYEF WGPR+ L
Sbjct: 528 LIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFL 587
Query: 662 ETTKMKILKFMAKIYNKDPMDWPEKYNEALEE 693
ET+KM +L+F+AK++ KDP WP Y EAL E
Sbjct: 588 ETSKMLVLRFLAKLHKKDPQSWPFHYLEALAE 619
Score = 152 bits (384), Expect = 1e-36
Identities = 94/273 (34%), Positives = 141/273 (51%), Gaps = 20/273 (7%)
Query: 693 EDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESRLESKARKL 752
E + + A G P P A V SP S + +SK + P S L+ +A L
Sbjct: 368 EGPSTSRALGLSESPGSSLPVVVSEVASV-SPGSSATQDNSKV--EAQPLSPLDERANAL 424
Query: 753 VQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVVLDPRNHSY 812
VQ L+ D K+P+ + ++ I RE D++NRA L +G +L +D +NH+Y
Sbjct: 425 VQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTKNHAY 484
Query: 813 TLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGLGVQA---- 868
+ N+ + +RP LM VLS IF+ GN RE ++ FL LG+
Sbjct: 485 IIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETN 544
Query: 869 ----GRKHVITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALRYVARIHRK 924
K +IT ++ Q+Y++ R+P ++P +YEF+WGPRA LETSKM LR++A++H+K
Sbjct: 545 GLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKK 604
Query: 925 EPQDWPQQYREAM---------EDEANRADVGH 948
+PQ WP Y EA+ EDE + D H
Sbjct: 605 DPQSWPFHYLEALAECEWEDTDEDEPDTGDSAH 637
Score = 36.2 bits (82), Expect = 0.15
Identities = 24/60 (40%), Positives = 31/60 (51%)
Query: 56 QGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTS 115
+GL EGPSTS + + EGPS + E S S +SE PG+S+ SE S S
Sbjct: 338 RGLSGWEGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVS 397
Score = 35.4 bits (80), Expect = 0.26
Identities = 24/54 (44%), Positives = 30/54 (55%)
Query: 110 EGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTS 163
EG STS + +G S L+A EG +TSR SE P +S+P SEV S S
Sbjct: 344 EGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVS 397
>gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 203 bits (517), Expect = 5e-52
Identities = 145/452 (32%), Positives = 229/452 (50%), Gaps = 50/452 (11%)
Query: 298 PTATEGLSTS----VQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELS-TSVPPTPGEGP 352
P A++ L S V +G +T V TP + + ++T +L+ T V +
Sbjct: 43 PKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSL 102
Query: 353 STSVLPIPGEGLSTSVPPT----ASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNP 408
+ + + ++P T S +DT V E + Q A + S
Sbjct: 103 AADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQS 162
Query: 409 GEGPSTLFSSSASVDR-------------NPSKCSLVLPSPRVTKASVDSDSEGPKGAEG 455
E T A R + S+ S RV+KA + S + + + G
Sbjct: 163 QENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMAR--RASRG 220
Query: 456 PIEFEVLRDCESPNSI----SIMGLNT------------SRVAITLKPQDPMEQNVA--- 496
PI F R + + +++ L + +++ + +P+ P ++VA
Sbjct: 221 PIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQ 280
Query: 497 ----ELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELD 552
+L+++LL KDQ+K PI+ S+M + I+KEY + +PEI+ RA LE +F +L+E+D
Sbjct: 281 GRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEID 340
Query: 553 PEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGV 612
H YILL+ L P L + + PK+GLLM++L IF+NGN++ EA IWE+L ++G+
Sbjct: 341 KNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGL 400
Query: 613 QRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFM 672
+ S+FG+ K+L++ EFV Q+YLDY V + P EYEFFWG RS+ ET+KMK+LKF
Sbjct: 401 RPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFA 460
Query: 673 AKIYNKDPMDWPEKYNEALEED---AARAFAE 701
K+ KDP +W +Y EA+E D AA A AE
Sbjct: 461 CKVQKKDPKEWAAQYREAMEADLKAAAEAAAE 492
Score = 154 bits (389), Expect = 4e-37
Identities = 80/227 (35%), Positives = 131/227 (57%), Gaps = 8/227 (3%)
Query: 726 SEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPD 785
+++ S AP + L+ +A LV+ L D TK+PI + +L I +E + V+P+
Sbjct: 260 AKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPE 319
Query: 786 LLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFI 845
++ RA +L V+G +L +D +H Y L + E + + + + P LM +LS I
Sbjct: 320 IIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSII 379
Query: 846 FIMGNHARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQY 897
F+ GN + E+ +W LR LG++ G H +IT ++ Q+Y+D RVP+S+P +Y
Sbjct: 380 FMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEY 439
Query: 898 EFVWGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
EF WG R+ ETSKMK L++ ++ +K+P++W QYREAME + A
Sbjct: 440 EFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAA 486
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/145 (24%), Positives = 54/145 (37%), Gaps = 14/145 (9%)
Query: 146 EEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPG 205
E P S SE S + T S P A E P+T + ST+ L
Sbjct: 41 ETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPAT-------QASSTTQL---- 89
Query: 206 EGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPG 265
T V A + L+ + + + ++P T T+ +S V T+ + A P
Sbjct: 90 --TDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVS-HVADTKVNTKAQETEAAPS 146
Query: 266 EGPSTSVLPAASDGQSISLVPTRGK 290
+ P+ P ++ QS TR K
Sbjct: 147 QAPADEPEPESAAAQSQENQDTRPK 171
>gi|19387846 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 203 bits (517), Expect = 5e-52
Identities = 145/452 (32%), Positives = 229/452 (50%), Gaps = 50/452 (11%)
Query: 298 PTATEGLSTS----VQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELS-TSVPPTPGEGP 352
P A++ L S V +G +T V TP + + ++T +L+ T V +
Sbjct: 43 PKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSL 102
Query: 353 STSVLPIPGEGLSTSVPPT----ASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNP 408
+ + + ++P T S +DT V E + Q A + S
Sbjct: 103 AADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQS 162
Query: 409 GEGPSTLFSSSASVDR-------------NPSKCSLVLPSPRVTKASVDSDSEGPKGAEG 455
E T A R + S+ S RV+KA + S + + + G
Sbjct: 163 QENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMAR--RASRG 220
Query: 456 PIEFEVLRDCESPNSI----SIMGLNT------------SRVAITLKPQDPMEQNVA--- 496
PI F R + + +++ L + +++ + +P+ P ++VA
Sbjct: 221 PIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQ 280
Query: 497 ----ELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELD 552
+L+++LL KDQ+K PI+ S+M + I+KEY + +PEI+ RA LE +F +L+E+D
Sbjct: 281 GRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEID 340
Query: 553 PEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGV 612
H YILL+ L P L + + PK+GLLM++L IF+NGN++ EA IWE+L ++G+
Sbjct: 341 KNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGL 400
Query: 613 QRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFM 672
+ S+FG+ K+L++ EFV Q+YLDY V + P EYEFFWG RS+ ET+KMK+LKF
Sbjct: 401 RPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFA 460
Query: 673 AKIYNKDPMDWPEKYNEALEED---AARAFAE 701
K+ KDP +W +Y EA+E D AA A AE
Sbjct: 461 CKVQKKDPKEWAAQYREAMEADLKAAAEAAAE 492
Score = 154 bits (389), Expect = 4e-37
Identities = 80/227 (35%), Positives = 131/227 (57%), Gaps = 8/227 (3%)
Query: 726 SEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPD 785
+++ S AP + L+ +A LV+ L D TK+PI + +L I +E + V+P+
Sbjct: 260 AKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPE 319
Query: 786 LLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFI 845
++ RA +L V+G +L +D +H Y L + E + + + + P LM +LS I
Sbjct: 320 IIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSII 379
Query: 846 FIMGNHARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQY 897
F+ GN + E+ +W LR LG++ G H +IT ++ Q+Y+D RVP+S+P +Y
Sbjct: 380 FMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEY 439
Query: 898 EFVWGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
EF WG R+ ETSKMK L++ ++ +K+P++W QYREAME + A
Sbjct: 440 EFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAA 486
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/145 (24%), Positives = 54/145 (37%), Gaps = 14/145 (9%)
Query: 146 EEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPG 205
E P S SE S + T S P A E P+T + ST+ L
Sbjct: 41 ETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPAT-------QASSTTQL---- 89
Query: 206 EGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPG 265
T V A + L+ + + + ++P T T+ +S V T+ + A P
Sbjct: 90 --TDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVS-HVADTKVNTKAQETEAAPS 146
Query: 266 EGPSTSVLPAASDGQSISLVPTRGK 290
+ P+ P ++ QS TR K
Sbjct: 147 QAPADEPEPESAAAQSQENQDTRPK 171
>gi|41350320 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 203 bits (517), Expect = 5e-52
Identities = 145/452 (32%), Positives = 229/452 (50%), Gaps = 50/452 (11%)
Query: 298 PTATEGLSTS----VQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELS-TSVPPTPGEGP 352
P A++ L S V +G +T V TP + + ++T +L+ T V +
Sbjct: 43 PKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSL 102
Query: 353 STSVLPIPGEGLSTSVPPT----ASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNP 408
+ + + ++P T S +DT V E + Q A + S
Sbjct: 103 AADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQS 162
Query: 409 GEGPSTLFSSSASVDR-------------NPSKCSLVLPSPRVTKASVDSDSEGPKGAEG 455
E T A R + S+ S RV+KA + S + + + G
Sbjct: 163 QENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMAR--RASRG 220
Query: 456 PIEFEVLRDCESPNSI----SIMGLNT------------SRVAITLKPQDPMEQNVA--- 496
PI F R + + +++ L + +++ + +P+ P ++VA
Sbjct: 221 PIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQ 280
Query: 497 ----ELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELD 552
+L+++LL KDQ+K PI+ S+M + I+KEY + +PEI+ RA LE +F +L+E+D
Sbjct: 281 GRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEID 340
Query: 553 PEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGV 612
H YILL+ L P L + + PK+GLLM++L IF+NGN++ EA IWE+L ++G+
Sbjct: 341 KNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGL 400
Query: 613 QRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFM 672
+ S+FG+ K+L++ EFV Q+YLDY V + P EYEFFWG RS+ ET+KMK+LKF
Sbjct: 401 RPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFA 460
Query: 673 AKIYNKDPMDWPEKYNEALEED---AARAFAE 701
K+ KDP +W +Y EA+E D AA A AE
Sbjct: 461 CKVQKKDPKEWAAQYREAMEADLKAAAEAAAE 492
Score = 154 bits (389), Expect = 4e-37
Identities = 80/227 (35%), Positives = 131/227 (57%), Gaps = 8/227 (3%)
Query: 726 SEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPD 785
+++ S AP + L+ +A LV+ L D TK+PI + +L I +E + V+P+
Sbjct: 260 AKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPE 319
Query: 786 LLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFI 845
++ RA +L V+G +L +D +H Y L + E + + + + P LM +LS I
Sbjct: 320 IIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSII 379
Query: 846 FIMGNHARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQY 897
F+ GN + E+ +W LR LG++ G H +IT ++ Q+Y+D RVP+S+P +Y
Sbjct: 380 FMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEY 439
Query: 898 EFVWGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
EF WG R+ ETSKMK L++ ++ +K+P++W QYREAME + A
Sbjct: 440 EFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAA 486
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/145 (24%), Positives = 54/145 (37%), Gaps = 14/145 (9%)
Query: 146 EEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPG 205
E P S SE S + T S P A E P+T + ST+ L
Sbjct: 41 ETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPAT-------QASSTTQL---- 89
Query: 206 EGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPG 265
T V A + L+ + + + ++P T T+ +S V T+ + A P
Sbjct: 90 --TDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVS-HVADTKVNTKAQETEAAPS 146
Query: 266 EGPSTSVLPAASDGQSISLVPTRGK 290
+ P+ P ++ QS TR K
Sbjct: 147 QAPADEPEPESAAAQSQENQDTRPK 171
>gi|29540551 trophinin isoform 2 [Homo sapiens]
Length = 706
Score = 194 bits (493), Expect = 3e-49
Identities = 111/281 (39%), Positives = 166/281 (59%), Gaps = 26/281 (9%)
Query: 475 GLNTSRVAITLKPQDP-----MEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQF 529
G N R+ +P P +++ +L+++LLVKDQ+K PI+ S+M +++EY F
Sbjct: 423 GSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYF 482
Query: 530 PEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNG--------PKM 581
PEI+ RA+ LE +FR L+E+D ++ YIL++ +ES G PK+
Sbjct: 483 PEIIERASYTLEKMFRVNLKEIDKQSSLYILIST---------QESSAGILGTTKDTPKL 533
Query: 582 GLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYR 641
GLLM+IL IF+NGN+A EA IWE+L ++G++ R S+FG ++L++ EFV Q+YL+Y+
Sbjct: 534 GLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYK 593
Query: 642 PVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALE---EDAARA 698
V + +P EYEFFWG RS+ ET+KMK+LKF ++ KDP DW +Y EA+E + AA A
Sbjct: 594 RVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVA 653
Query: 699 FAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHS 739
AE +A P + SP + PHS
Sbjct: 654 VAEA-EARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHS 693
Score = 147 bits (371), Expect = 5e-35
Identities = 78/210 (37%), Positives = 125/210 (59%), Gaps = 9/210 (4%)
Query: 745 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV 804
L+ +A KLV+ L+ D TK+PI + +L + +E + FP+++ RA+ TL ++ L
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 805 LDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGL 864
+D ++ Y L + +E + + + P LM +LS IF+ GN A E+ +W LR L
Sbjct: 504 IDKQSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 865 GVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALR 916
G++ G +H +IT ++ Q+Y++ RVP+S P +YEF WG R+ ETSKMK L+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 917 YVARIHRKEPQDWPQQYREAMEDEANRADV 946
+ R+ +K+P+DW QYREA+E E A V
Sbjct: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAV 652
>gi|29540541 trophinin isoform 2 [Homo sapiens]
Length = 706
Score = 194 bits (493), Expect = 3e-49
Identities = 111/281 (39%), Positives = 166/281 (59%), Gaps = 26/281 (9%)
Query: 475 GLNTSRVAITLKPQDP-----MEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQF 529
G N R+ +P P +++ +L+++LLVKDQ+K PI+ S+M +++EY F
Sbjct: 423 GSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYF 482
Query: 530 PEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNG--------PKM 581
PEI+ RA+ LE +FR L+E+D ++ YIL++ +ES G PK+
Sbjct: 483 PEIIERASYTLEKMFRVNLKEIDKQSSLYILIST---------QESSAGILGTTKDTPKL 533
Query: 582 GLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYR 641
GLLM+IL IF+NGN+A EA IWE+L ++G++ R S+FG ++L++ EFV Q+YL+Y+
Sbjct: 534 GLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYK 593
Query: 642 PVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALE---EDAARA 698
V + +P EYEFFWG RS+ ET+KMK+LKF ++ KDP DW +Y EA+E + AA A
Sbjct: 594 RVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVA 653
Query: 699 FAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHS 739
AE +A P + SP + PHS
Sbjct: 654 VAEA-EARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHS 693
Score = 147 bits (371), Expect = 5e-35
Identities = 78/210 (37%), Positives = 125/210 (59%), Gaps = 9/210 (4%)
Query: 745 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV 804
L+ +A KLV+ L+ D TK+PI + +L + +E + FP+++ RA+ TL ++ L
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 805 LDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGL 864
+D ++ Y L + +E + + + P LM +LS IF+ GN A E+ +W LR L
Sbjct: 504 IDKQSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 865 GVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALR 916
G++ G +H +IT ++ Q+Y++ RVP+S P +YEF WG R+ ETSKMK L+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 917 YVARIHRKEPQDWPQQYREAMEDEANRADV 946
+ R+ +K+P+DW QYREA+E E A V
Sbjct: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAV 652
>gi|89276766 trophinin isoform 5 [Homo sapiens]
Length = 1431
Score = 191 bits (484), Expect = 4e-48
Identities = 104/243 (42%), Positives = 156/243 (64%), Gaps = 25/243 (10%)
Query: 475 GLNTSRVAITLKPQDP-----MEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQF 529
G N R+ +P P +++ +L+++LLVKDQ+K PI+ S+M +++EY F
Sbjct: 423 GSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYF 482
Query: 530 PEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNG--------PKM 581
PEI+ RA+ LE +FR L+E+D ++ YIL++ +ES G PK+
Sbjct: 483 PEIIERASYTLEKMFRVNLKEIDKQSSLYILIST---------QESSAGILGTTKDTPKL 533
Query: 582 GLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYR 641
GLLM+IL IF+NGN+A EA IWE+L ++G++ R S+FG ++L++ EFV Q+YL+Y+
Sbjct: 534 GLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYK 593
Query: 642 PVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALE---EDAARA 698
V + +P EYEFFWG RS+ ET+KMK+LKF ++ KDP DW +Y EA+E + AA A
Sbjct: 594 RVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVA 653
Query: 699 FAE 701
AE
Sbjct: 654 VAE 656
Score = 147 bits (371), Expect = 5e-35
Identities = 78/210 (37%), Positives = 125/210 (59%), Gaps = 9/210 (4%)
Query: 745 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV 804
L+ +A KLV+ L+ D TK+PI + +L + +E + FP+++ RA+ TL ++ L
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 805 LDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGL 864
+D ++ Y L + +E + + + P LM +LS IF+ GN A E+ +W LR L
Sbjct: 504 IDKQSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 865 GVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALR 916
G++ G +H +IT ++ Q+Y++ RVP+S P +YEF WG R+ ETSKMK L+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 917 YVARIHRKEPQDWPQQYREAMEDEANRADV 946
+ R+ +K+P+DW QYREA+E E A V
Sbjct: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAV 652
Score = 48.1 bits (113), Expect = 4e-05
Identities = 89/319 (27%), Positives = 117/319 (36%), Gaps = 36/319 (11%)
Query: 107 TPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPP 166
T S + G P+ S G ++ AS G S + S STS S P T+
Sbjct: 1042 TLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSA--CFSGAPITN--- 1096
Query: 167 TPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQA 226
PG G + S +A G + S PS S+ G P TSV G S
Sbjct: 1097 -PGFGGAFST--SAGFGGALSTAADFGGTPSNSI--GFGAAPSTSVSFGGAHGTSLCFGG 1151
Query: 227 TPDE----GPSTSV------PPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAA 276
P G +++ PP+ + S P+ +GPSTS + G G ST+
Sbjct: 1152 APSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNA---- 1207
Query: 277 SDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTA 336
G L + G G + GLSTS G G+S GGG TS
Sbjct: 1208 --GFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGF----GGGPGTST--GF 1259
Query: 337 TEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTA 396
L TS + G G S G GL TS G++ S T G A +
Sbjct: 1260 GGGLGTSAGFSGGLGTSAGF----GGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLST 1315
Query: 397 PDGPGSSVLPNPGEGPSTL 415
DG GS + G ST+
Sbjct: 1316 SDGFGSRPNASFDRGLSTI 1334
Score = 46.2 bits (108), Expect = 1e-04
Identities = 81/288 (28%), Positives = 104/288 (36%), Gaps = 35/288 (12%)
Query: 58 LCASEGPSTSVLPTSAEGPSTFV--PPTISEASSASGQPTISEGPGTSVLPTPSEGLSTS 115
LC PSTS+ SA + PP+ S S + P+ +GP TS + GLST+
Sbjct: 1147 LCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTN 1206
Query: 116 GPPTISKGLCTSV----TLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEG 171
GL TS L S G + +S + P TS G G
Sbjct: 1207 A--GFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLG 1264
Query: 172 TSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEG 231
TS G S + + G G G GT+ +T G S G
Sbjct: 1265 TSA--------GFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSG----G 1312
Query: 232 PSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVL--PAASDGQS---ISLVP 286
STS +G + + D G ST + G ST P+ S G S S+V
Sbjct: 1313 LSTS------DGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVG 1366
Query: 287 TRGKGSSTSV---PPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTS 331
G G ST V +T G S AG G + GGG STS
Sbjct: 1367 FSG-GPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTS 1413
Score = 44.7 bits (104), Expect = 4e-04
Identities = 95/408 (23%), Positives = 143/408 (35%), Gaps = 20/408 (4%)
Query: 60 ASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPT----ISEGPGTSVLPTPSEGLSTS 115
A E S + G ST + + S +G P+ S GPG + PS S S
Sbjct: 711 AQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFS 770
Query: 116 GPPTISKG--LCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTS 173
+IS G L TS + +++ + ++S S+ + +P TS + G +S
Sbjct: 771 NTASISFGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSS 830
Query: 174 TSVPPT--------AYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQ 225
S P + A G ++ T S + G P TS ++ ST
Sbjct: 831 FSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFG 890
Query: 226 ATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLV 285
P+++ + + G S G STSV S S +
Sbjct: 891 GILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFG 950
Query: 286 PTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVP 345
T P+ G ++ +A GS + GG +STS T LSTSV
Sbjct: 951 GTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGT--LSTSV- 1007
Query: 346 PTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVL 405
G P TSV G L+T+ + ++T T P+ G G ++
Sbjct: 1008 -CFGGSPGTSV--SFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALN 1064
Query: 406 PNPGEGPSTLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSEGPKGA 453
N G + S+S S + S C P S S G GA
Sbjct: 1065 TNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGA 1112
>gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]
Length = 834
Score = 190 bits (482), Expect = 6e-48
Identities = 199/718 (27%), Positives = 310/718 (43%), Gaps = 76/718 (10%)
Query: 39 DVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISE 98
D P S + P+ +L C G S + S E S + T+ EA ISE
Sbjct: 45 DPPYSQLRDPPA---VLSCYCTPLGASPAPAEASVED-SALLMQTLMEAIQ------ISE 94
Query: 99 GPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSV-----P 153
P T+ T + +S PPT ++ V+ AA+ ++ + ++ + V
Sbjct: 95 APPTNQA-TAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQA 153
Query: 154 PTASEVPSTSLPPT-PGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSV 212
A +VP+T + + P AY+ + T + + S + + T V
Sbjct: 154 HNAKDVPNTQPKAAFKSQNATPKGPNAAYD--FSQAATTGELAANKSEMAFKAQNATTKV 211
Query: 213 PLAATEGLSTSVQATPDEGPSTSVPPTA-TEGLSTPVPPTRDEGPSTSVPAT-------- 263
AT S S+ A P A + P T+ + + + AT
Sbjct: 212 GPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETD 271
Query: 264 PG-EGPSTSVLPAASDGQSISLVPTRG--KGSST-SVPPTATEGLSTSVQP----TAGEG 315
PG P + ++DG + +R +G T + E S+ Q AG
Sbjct: 272 PGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTW 331
Query: 316 SSTSVPPTPGGGLSTSVPPTATEELSTSVP-----PTPGEGPSTSVLPIPGEGLSTSVPP 370
S VP T T PP A + P P+ + + P + P
Sbjct: 332 RSAPVPVT------TQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTP 385
Query: 371 TASDG----SDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNP-----------GEGPSTL 415
A + + P P + ++ P PG V PNP G T
Sbjct: 386 PAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTP 445
Query: 416 FSSSASVD-RNPSKCSLVLPSPRVTKASVDSDSEGPKG---AEGPIEFEVLRDCESPNSI 471
D + P L P + +D P A+ PI + SPN
Sbjct: 446 PGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLR 505
Query: 472 SIMGLNTSRVAITLKPQDP--MEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQF 529
S+ +P+D +++ +L+++L++KD +K PI+ SEM I++EY + +
Sbjct: 506 PSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVY 565
Query: 530 PEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEG-LEESPNGPKMGLLMMIL 588
PEI+ RA LE F +L+E+D E H YIL++ P G L + + PK+GLL++IL
Sbjct: 566 PEIIERACFVLEKKFGIQLKEIDKEEHLYILIST--PESLAGILGTTKDTPKLGLLLVIL 623
Query: 589 GQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKP 648
G IF+NGN+A EA +WE L +MG++ R + G+ ++LL+ EFV Q+YLDYR V + P
Sbjct: 624 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 683
Query: 649 VEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEE-----DAARAFAE 701
EYEF WG RS+ ET+KMK+L+F+A++ +DP DW ++ EA +E DAA A AE
Sbjct: 684 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAE 741
Score = 147 bits (372), Expect = 4e-35
Identities = 91/280 (32%), Positives = 145/280 (51%), Gaps = 28/280 (10%)
Query: 680 PMDWPEKYNEALEEDAARA---FAEGWQAL---PHFRRPFFEEAAAEVPSPDSEVSSYSS 733
P DWP + L D A WQ L P+ R PSP+S S
Sbjct: 469 PPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLR-----------PSPNSRASQNPG 517
Query: 734 KYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAART 793
P + L+ +A KLV+ +L D TK+PI + +L I RE + V+P+++ RA
Sbjct: 518 AAQPRD--VALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFV 575
Query: 794 LNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHAR 853
L +G +L +D H Y L + E + + + P L+ +L IF+ GN A
Sbjct: 576 LEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRAS 634
Query: 854 ESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRA 905
E+ +W LR +G++ G +H ++T ++ Q+Y+D RVP+S+P +YEF+WG R+
Sbjct: 635 EAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRS 694
Query: 906 RLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRAD 945
ETSKMK LR++A + +++P+DW Q+ EA ++ + D
Sbjct: 695 YHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALD 734
>gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]
Length = 778
Score = 188 bits (478), Expect = 2e-47
Identities = 189/696 (27%), Positives = 294/696 (42%), Gaps = 88/696 (12%)
Query: 54 ILQGLCASEGPSTSVLPTSAEGPSTFVPPTISE-----ASSASGQPTISEGPGTSVLPTP 108
+++ + SE P T+ T+A P + PPT +E S+A+ +P + + P
Sbjct: 30 LMEAIQISEAPPTNQA-TAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGP 88
Query: 109 SEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTP 168
+ G+ +K + + AA + +N + ++ + T + S
Sbjct: 89 N-GVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 147
Query: 169 GEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEG-------LS 221
+ +T V P A S S+ D S P T P A T+ ++
Sbjct: 148 AQNATTKVGPNATYNFSQSLNAN-DLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMA 206
Query: 222 TSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQS 281
TS QA + P S P AT S ++ T + + + S G
Sbjct: 207 TS-QADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQ 265
Query: 282 ISLVPTRGKGSSTSVPPTATE--GLSTSV--------QPTAGEGSSTS--VPPTPGGGLS 329
G S VP T G +V Q +G + T+ PP +
Sbjct: 266 RRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPA 325
Query: 330 TSVPPTATEELSTSVP---------------PTPGEGPSTSVLPIPGEGLSTSVPPTASD 374
PP ++ P P P P V P P L+ PP
Sbjct: 326 RQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNP---LAWQNPPGWQT 382
Query: 375 GSDTSVPPT---PGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSKCSL 431
PP P + P PD P P P + P A P +L
Sbjct: 383 PPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNL 442
Query: 432 VLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLKPQDPM 491
PSP + + S+ P A+ P ++++
Sbjct: 443 -RPSPNLRPSPNSRASQNPGAAQ-------------PRDVALL----------------- 471
Query: 492 EQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELREL 551
++ +L+++L++KD +K PI+ SEM I++EY + +PEI+ RA LE F +L+E+
Sbjct: 472 QERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEI 531
Query: 552 DPEAHTYILLNKLGPVPFEG-LEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRM 610
D E H YIL++ P G L + + PK+GLL++ILG IF+NGN+A EA +WE L +M
Sbjct: 532 DKEEHLYILIST--PESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 589
Query: 611 GVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILK 670
G++ R + G+ ++LL+ EFV Q+YLDYR V + P EYEF WG RS+ ET+KMK+L+
Sbjct: 590 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 649
Query: 671 FMAKIYNKDPMDWPEKYNEALEE-----DAARAFAE 701
F+A++ +DP DW ++ EA +E DAA A AE
Sbjct: 650 FIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAE 685
Score = 147 bits (372), Expect = 4e-35
Identities = 91/280 (32%), Positives = 145/280 (51%), Gaps = 28/280 (10%)
Query: 680 PMDWPEKYNEALEEDAARA---FAEGWQAL---PHFRRPFFEEAAAEVPSPDSEVSSYSS 733
P DWP + L D A WQ L P+ R PSP+S S
Sbjct: 413 PPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLR-----------PSPNSRASQNPG 461
Query: 734 KYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAART 793
P + L+ +A KLV+ +L D TK+PI + +L I RE + V+P+++ RA
Sbjct: 462 AAQPRD--VALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFV 519
Query: 794 LNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHAR 853
L +G +L +D H Y L + E + + + P L+ +L IF+ GN A
Sbjct: 520 LEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRAS 578
Query: 854 ESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRA 905
E+ +W LR +G++ G +H ++T ++ Q+Y+D RVP+S+P +YEF+WG R+
Sbjct: 579 EAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRS 638
Query: 906 RLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRAD 945
ETSKMK LR++A + +++P+DW Q+ EA ++ + D
Sbjct: 639 YHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALD 678
>gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]
Length = 778
Score = 188 bits (478), Expect = 2e-47
Identities = 189/696 (27%), Positives = 294/696 (42%), Gaps = 88/696 (12%)
Query: 54 ILQGLCASEGPSTSVLPTSAEGPSTFVPPTISE-----ASSASGQPTISEGPGTSVLPTP 108
+++ + SE P T+ T+A P + PPT +E S+A+ +P + + P
Sbjct: 30 LMEAIQISEAPPTNQA-TAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGP 88
Query: 109 SEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTP 168
+ G+ +K + + AA + +N + ++ + T + S
Sbjct: 89 N-GVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFK 147
Query: 169 GEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEG-------LS 221
+ +T V P A S S+ D S P T P A T+ ++
Sbjct: 148 AQNATTKVGPNATYNFSQSLNAN-DLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMA 206
Query: 222 TSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQS 281
TS QA + P S P AT S ++ T + + + S G
Sbjct: 207 TS-QADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQ 265
Query: 282 ISLVPTRGKGSSTSVPPTATE--GLSTSV--------QPTAGEGSSTS--VPPTPGGGLS 329
G S VP T G +V Q +G + T+ PP +
Sbjct: 266 RRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPA 325
Query: 330 TSVPPTATEELSTSVP---------------PTPGEGPSTSVLPIPGEGLSTSVPPTASD 374
PP ++ P P P P V P P L+ PP
Sbjct: 326 RQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNP---LAWQNPPGWQT 382
Query: 375 GSDTSVPPT---PGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSKCSL 431
PP P + P PD P P P + P A P +L
Sbjct: 383 PPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNL 442
Query: 432 VLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLKPQDPM 491
PSP + + S+ P A+ P ++++
Sbjct: 443 -RPSPNLRPSPNSRASQNPGAAQ-------------PRDVALL----------------- 471
Query: 492 EQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELREL 551
++ +L+++L++KD +K PI+ SEM I++EY + +PEI+ RA LE F +L+E+
Sbjct: 472 QERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEI 531
Query: 552 DPEAHTYILLNKLGPVPFEG-LEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRM 610
D E H YIL++ P G L + + PK+GLL++ILG IF+NGN+A EA +WE L +M
Sbjct: 532 DKEEHLYILIST--PESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 589
Query: 611 GVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILK 670
G++ R + G+ ++LL+ EFV Q+YLDYR V + P EYEF WG RS+ ET+KMK+L+
Sbjct: 590 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 649
Query: 671 FMAKIYNKDPMDWPEKYNEALEE-----DAARAFAE 701
F+A++ +DP DW ++ EA +E DAA A AE
Sbjct: 650 FIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAE 685
Score = 147 bits (372), Expect = 4e-35
Identities = 91/280 (32%), Positives = 145/280 (51%), Gaps = 28/280 (10%)
Query: 680 PMDWPEKYNEALEEDAARA---FAEGWQAL---PHFRRPFFEEAAAEVPSPDSEVSSYSS 733
P DWP + L D A WQ L P+ R PSP+S S
Sbjct: 413 PPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLR-----------PSPNSRASQNPG 461
Query: 734 KYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAART 793
P + L+ +A KLV+ +L D TK+PI + +L I RE + V+P+++ RA
Sbjct: 462 AAQPRD--VALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFV 519
Query: 794 LNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHAR 853
L +G +L +D H Y L + E + + + P L+ +L IF+ GN A
Sbjct: 520 LEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGNRAS 578
Query: 854 ESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRA 905
E+ +W LR +G++ G +H ++T ++ Q+Y+D RVP+S+P +YEF+WG R+
Sbjct: 579 EAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRS 638
Query: 906 RLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRAD 945
ETSKMK LR++A + +++P+DW Q+ EA ++ + D
Sbjct: 639 YHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALD 678
>gi|153791873 melanoma antigen family B, 16 [Homo sapiens]
Length = 324
Score = 188 bits (477), Expect = 2e-47
Identities = 113/312 (36%), Positives = 172/312 (55%), Gaps = 27/312 (8%)
Query: 390 TLVQPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSEG 449
TL+ + P PG E P+ S V + S CS + + + D S
Sbjct: 37 TLLSSSHPLVPGKLK-----EAPAAKAESPLEVPQ--SFCSSSIAVTTTSSSESDEASSN 89
Query: 450 PKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSK 509
+ + P E D P ++ P D ++Q VA L+ F+L K Q K
Sbjct: 90 QEEEDSPSSSE---DTSDPRNV---------------PADALDQKVAFLVNFMLHKCQMK 131
Query: 510 YPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPF 569
PI +++M + I+K+ + F EIL RA+ HLE IF ++ E+DP H Y L KLG + +
Sbjct: 132 KPITKADMLKIIIKDDESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLG-LTY 190
Query: 570 EGLEESPNG-PKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLL 628
+G+ G PK GLL+++LG IF+ GN+A E E+WE+L GV ++ IFG P+ L+
Sbjct: 191 DGMLSGEKGVPKTGLLIIVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLI 250
Query: 629 SVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYN 688
+ +FV ++YL+Y+ V + P YEF WGPR+ ET+KMK+L+F+AK++ P +P +Y
Sbjct: 251 TKDFVKEKYLEYQQVANSDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYA 310
Query: 689 EALEEDAARAFA 700
EAL+E+ RA A
Sbjct: 311 EALKEEEERARA 322
Score = 145 bits (367), Expect = 1e-34
Identities = 83/238 (34%), Positives = 127/238 (53%), Gaps = 9/238 (3%)
Query: 715 EEAAAEVPSPDSEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYY 774
+EA++ DS SS + P + P L+ K LV L K PI K +L
Sbjct: 84 DEASSNQEEEDSPSSSEDTS-DPRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKI 142
Query: 775 IGRECSKVFPDLLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPG 834
I ++ F ++L RA+ L ++G ++V +DP H Y L+ + + + P
Sbjct: 143 IIKDDESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPK 202
Query: 835 NNFLMQVLSFIFIMGNHARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDS 886
L+ VL IF+ GN A E VW L GV +G+KH +IT ++ ++Y++
Sbjct: 203 TGLLIIVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEY 262
Query: 887 LRVPDSDPVQYEFVWGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
+V +SDP +YEF+WGPRA+ ETSKMK L +VA++H P +P QY EA+++E RA
Sbjct: 263 QQVANSDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEALKEEEERA 320
>gi|4505085 melanoma antigen family B, 4 [Homo sapiens]
Length = 346
Score = 181 bits (459), Expect = 3e-45
Identities = 109/286 (38%), Positives = 170/286 (59%), Gaps = 10/286 (3%)
Query: 417 SSSASVDRNPSKCSLVLPSPRVTKASVDSDSEGPK-GAEGPIEFEVLRDCESPNSISIMG 475
SSS+SV R+ + SL P+ + + S G + + +D E+ +S S
Sbjct: 40 SSSSSVLRDTASSSLAFGIPQEPQREPPTTSAAAAMSCTGSDKGDESQDEENASS-SQAS 98
Query: 476 LNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRR 535
+T R +LK D + + L+QFLL K + K P ++EM + I K+Y+ FPEI R+
Sbjct: 99 TSTER---SLK--DSLTRKTKMLVQFLLYKYKMKEPTTKAEMLKIISKKYKEHFPEIFRK 153
Query: 536 AAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESP-NGPKMGLLMMILGQIFLN 594
+ E +F L+E++P H+YIL++ LGP +G + S P+ GLLM +L IFLN
Sbjct: 154 VSQRTELVFGLALKEVNPTTHSYILVSMLGPN--DGNQSSAWTLPRNGLLMPLLSVIFLN 211
Query: 595 GNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFF 654
GN A+E EIWE L +G+ +R IFG P++L++ + V ++YL+Y+ V + P Y+F
Sbjct: 212 GNCAREEEIWEFLNMLGIYDGKRHLIFGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQFL 271
Query: 655 WGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEEDAARAFA 700
WGPR+H ET+KMK+L+F+AK+ + P ++P Y EAL ++ RA A
Sbjct: 272 WGPRAHAETSKMKVLEFLAKVNDTTPNNFPLLYEEALRDEEERAGA 317
Score = 140 bits (353), Expect = 6e-33
Identities = 89/279 (31%), Positives = 139/279 (49%), Gaps = 20/279 (7%)
Query: 684 PEKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAA----------EVPSPDSEVSSYSS 733
P + L + A+ + A G P P AAA E ++ SS +S
Sbjct: 39 PSSSSSVLRDTASSSLAFGIPQEPQREPPTTSAAAAMSCTGSDKGDESQDEENASSSQAS 98
Query: 734 KYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAART 793
S +S L K + LVQ L K P K +L I ++ + FP++ + ++
Sbjct: 99 TSTERSLKDS-LTRKTKMLVQFLLYKYKMKEPTTKAEMLKIISKKYKEHFPEIFRKVSQR 157
Query: 794 LNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHAR 853
V+G L ++P HSY L + + + + P N LM +LS IF+ GN AR
Sbjct: 158 TELVFGLALKEVNPTTHSYILVSMLGPNDGNQS-SAWTLPRNGLLMPLLSVIFLNGNCAR 216
Query: 854 ESAVWAFLRGLGVQAGRKHVI--------TCRYLSQRYIDSLRVPDSDPVQYEFVWGPRA 905
E +W FL LG+ G++H+I T + ++Y++ +VP+SDP +Y+F+WGPRA
Sbjct: 217 EEEIWEFLNMLGIYDGKRHLIFGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQFLWGPRA 276
Query: 906 RLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
ETSKMK L ++A+++ P ++P Y EA+ DE RA
Sbjct: 277 HAETSKMKVLEFLAKVNDTTPNNFPLLYEEALRDEEERA 315
>gi|27734781 melanoma antigen family B, 18 [Homo sapiens]
Length = 343
Score = 181 bits (459), Expect = 3e-45
Identities = 92/235 (39%), Positives = 147/235 (62%), Gaps = 1/235 (0%)
Query: 466 ESPNSISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEY 525
E +S L +SR A K +DP+ + V L+ FLL K ++K PI + +M ++++++
Sbjct: 83 EGASSQDEKSLGSSREAEGWK-EDPLNKKVVSLVHFLLQKYETKEPITKGDMIKFVIRKD 141
Query: 526 RNQFPEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLM 585
+ F EIL+RA+ H+E +L+E+DP H Y +KL E + PK GLLM
Sbjct: 142 KCHFNEILKRASEHMELALGVDLKEVDPIRHYYAFFSKLDLTYDETTSDEEKIPKTGLLM 201
Query: 586 MILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTD 645
+ LG IFLNGN+A E +WE++ MGV +R+ ++G+P+++++ + V +YL+Y+ V +
Sbjct: 202 IALGVIFLNGNRAPEEAVWEIMNMMGVYADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPN 261
Query: 646 CKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEEDAARAFA 700
P YEF WGPR+H ET+KMK+L+F+AKI++ P +P Y EAL ++ R A
Sbjct: 262 SDPPRYEFLWGPRAHAETSKMKVLEFVAKIHDTVPSAFPSCYEEALRDEEQRTQA 316
Score = 147 bits (371), Expect = 5e-35
Identities = 90/269 (33%), Positives = 126/269 (46%), Gaps = 24/269 (8%)
Query: 699 FAEGWQALPHFRRPFFEEAAAEVPSPDSEVS----------------SYSSKYAPHSWPE 742
F + Q LP P EA PS + ++ S S W E
Sbjct: 45 FGDRPQNLPAAETPSIPEALQGAPSTTNAIAPVSCSSNEGASSQDEKSLGSSREAEGWKE 104
Query: 743 SRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTEL 802
L K LV L TK PI K ++ ++ R+ F ++L RA+ + G +L
Sbjct: 105 DPLNKKVVSLVHFLLQKYETKEPITKGDMIKFVIRKDKCHFNEILKRASEHMELALGVDL 164
Query: 803 VVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLR 862
+DP H Y +++ ++ E D P LM L IF+ GN A E AVW +
Sbjct: 165 KEVDPIRHYYAFFSKLDLTYDETTSDEEKIPKTGLLMIALGVIFLNGNRAPEEAVWEIMN 224
Query: 863 GLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKA 914
+GV A RKH V+T + +Y++ +VP+SDP +YEF+WGPRA ETSKMK
Sbjct: 225 MMGVYADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPNSDPPRYEFLWGPRAHAETSKMKV 284
Query: 915 LRYVARIHRKEPQDWPQQYREAMEDEANR 943
L +VA+IH P +P Y EA+ DE R
Sbjct: 285 LEFVAKIHDTVPSAFPSCYEEALRDEEQR 313
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 179 bits (453), Expect = 1e-44
Identities = 160/543 (29%), Positives = 246/543 (45%), Gaps = 44/543 (8%)
Query: 177 PPTAYEGPSTSVVP-TPDEGPS-TSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPST 234
PP + S P +P +G S L +P +S P + + S Q+ P EGP
Sbjct: 599 PPQGEDSMSPLYFPQSPLQGEEFQSSLQSPVSICSSSTPSSLPQSFPESSQSPP-EGPVQ 657
Query: 235 SV---PPTATEGL--STPV--PPTRDEGPST----SVPATPGEGP---STSVLPAASDGQ 280
S P + EG+ +P+ P + EG + +P +P EG S+ P +
Sbjct: 658 SPLHSPQSPPEGMHSQSPLQSPESAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSPPEW 717
Query: 281 SISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEEL 340
SL P PP + S+ P + SSTS+ S+P + E
Sbjct: 718 EDSLSPLH----FPQFPPQGEDFQSSLQSPVSICSSSTSL----------SLPQSFPES- 762
Query: 341 STSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEG-ASTLVQPTAPDG 399
P +P EGP+ S L P + + S S P +P EG A + +Q
Sbjct: 763 ----PQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHES-PQSPPEGPAQSPLQSPVSSF 817
Query: 400 PGSSVLPNPGEGPSTLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSEGPKGAEGPIEF 459
P S+ P + F SS S + S L SP ++ +S S S + + P++
Sbjct: 818 PSSTSSSLSQSSPVSSFPSSTSSSLSKSSPESPLQSPVISFSSSTSLSPFSEESSSPVDE 877
Query: 460 EVLRDCESPNSISIMGLNTSRVAITLKP--QDPMEQNVAELLQFLLVKDQSKYPIRESEM 517
S + L S I +P +++ V EL +FLL+K Q K PI ++EM
Sbjct: 878 YT---SSSDTLLESDSLTDSESLIESEPLFTYTLDEKVDELARFLLLKYQVKQPITKAEM 934
Query: 518 REYIVKEYRNQFPEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPN 577
++ Y FP I R+A +E +F LRE+DP+ +Y+ +N L L +
Sbjct: 935 LTNVISRYTGYFPVIFRKAREFIEILFGISLREVDPD-DSYVFVNTLDLTSEGCLSDEQG 993
Query: 578 GPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRY 637
+ LL++IL IF+ G A E IW++L +GV+ R FG P+ LL+ +V + Y
Sbjct: 994 MSQNRLLILILSIIFIKGTYASEEVIWDVLSGIGVRAGREHFAFGEPRELLTKVWVQEHY 1053
Query: 638 LDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEEDAAR 697
L+YR V + P YEF WGPR+H E K K+++F+A + N P+ +P Y +AL++ R
Sbjct: 1054 LEYREVPNSSPPRYEFLWGPRAHSEVIKRKVVEFLAMLKNTVPITFPSSYKDALKDVEER 1113
Query: 698 AFA 700
A A
Sbjct: 1114 AQA 1116
Score = 119 bits (297), Expect = 2e-26
Identities = 75/253 (29%), Positives = 122/253 (48%), Gaps = 24/253 (9%)
Query: 712 PFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESR------------LESKARKLVQLFLLM 759
PF EE+++ V D SS + S +S L+ K +L + LL
Sbjct: 866 PFSEESSSPV---DEYTSSSDTLLESDSLTDSESLIESEPLFTYTLDEKVDELARFLLLK 922
Query: 760 DSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVVLDPRNHSYTLYNRRE 819
K PI K +L + + FP + +A + ++G L +DP + SY N +
Sbjct: 923 YQVKQPITKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDP-DDSYVFVNTLD 981
Query: 820 MEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGLGVQAGRKH------- 872
+ + D N L+ +LS IFI G +A E +W L G+GV+AGR+H
Sbjct: 982 LTSEGCLSDEQGMSQNRLLILILSIIFIKGTYASEEVIWDVLSGIGVRAGREHFAFGEPR 1041
Query: 873 -VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALRYVARIHRKEPQDWPQ 931
++T ++ + Y++ VP+S P +YEF+WGPRA E K K + ++A + P +P
Sbjct: 1042 ELLTKVWVQEHYLEYREVPNSSPPRYEFLWGPRAHSEVIKRKVVEFLAMLKNTVPITFPS 1101
Query: 932 QYREAMEDEANRA 944
Y++A++D RA
Sbjct: 1102 SYKDALKDVEERA 1114
>gi|73623441 melanoma antigen family B, 10 [Homo sapiens]
Length = 347
Score = 177 bits (449), Expect = 4e-44
Identities = 96/264 (36%), Positives = 152/264 (57%), Gaps = 17/264 (6%)
Query: 439 TKASVDSDSEGPKGAEGPIEFEVL--RDCESPNSISIMGLNTSRVAITLKPQDPMEQNVA 496
T A+ S + P+G +E + +D E+ +S P+ P+++ V
Sbjct: 72 TSATAASHTRHPEGVNDQMEERPICTQDLEATDSF---------------PRGPVDEKVI 116
Query: 497 ELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELDPEAH 556
L+ +LL K Q K PI +++M + + ++QFP IL RA+ HLE IF +L+E++P H
Sbjct: 117 ILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLKEVEPNKH 176
Query: 557 TYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRER 616
Y+L+NKL L + PK GLLM +LG IF NGN E E+W++ MG+
Sbjct: 177 IYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNTMGLYDGI 236
Query: 617 RLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIY 676
+FG P++LL+ + V + YL+Y+ V + P Y+F WGPR+H ET+KMK+L+F+AK+
Sbjct: 237 EHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVN 296
Query: 677 NKDPMDWPEKYNEALEEDAARAFA 700
+ P ++ Y EAL+++ RA A
Sbjct: 297 DTAPSEFSNWYTEALQDEEERARA 320
Score = 131 bits (329), Expect = 3e-30
Identities = 71/217 (32%), Positives = 113/217 (52%), Gaps = 8/217 (3%)
Query: 736 APHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLN 795
A S+P ++ K LV L K PI K +L + + FP +L+RA+ L
Sbjct: 102 ATDSFPRGPVDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLE 161
Query: 796 HVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARES 855
++G +L ++P H Y L N+ ++ ++ D P LM VL IF GN E
Sbjct: 162 LIFGLDLKEVEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEE 221
Query: 856 AVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARL 907
VW +G+ G +H ++T + + Y++ +VP+SDP +Y+F+WGPRA
Sbjct: 222 EVWKVFNTMGLYDGIEHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHA 281
Query: 908 ETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
ETSKMK L ++A+++ P ++ Y EA++DE RA
Sbjct: 282 ETSKMKVLEFLAKVNDTAPSEFSNWYTEALQDEEERA 318
>gi|58530863 melanoma antigen family A, 10 [Homo sapiens]
Length = 369
Score = 176 bits (445), Expect = 1e-43
Identities = 110/331 (33%), Positives = 176/331 (53%), Gaps = 33/331 (9%)
Query: 386 EGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSKCSLVLPSPRVTKASVDS 445
EGA P A + SS PS+ SSS+S + S C ++PS T V +
Sbjct: 26 EGAQA---PLAVEEDASSSTSTSSSFPSSFPSSSSS---SSSSCYPLIPS---TPEEVSA 76
Query: 446 DSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLK-----------------PQ 488
D E P P ++ C SP+ ++ + L+ S + + P+
Sbjct: 77 DDETPNP---PQSAQIA--CSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPR 131
Query: 489 DPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFEL 548
+++ V +L+QFLL K Q K PI ++E+ E ++K Y + FP + A+ + +F ++
Sbjct: 132 SEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDV 191
Query: 549 RELDPEAHTYILLNKLGPVPFEG-LEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEML 607
+E+DP H+++L+ LG + ++G L + + PK G+L++IL IF+ G E IWE L
Sbjct: 192 KEVDPTGHSFVLVTSLG-LTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEAL 250
Query: 608 WRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMK 667
MG+ I+G P++LL+ ++V + YL+YR V P YEF WGPR+H E KM
Sbjct: 251 NMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMS 310
Query: 668 ILKFMAKIYNKDPMDWPEKYNEALEEDAARA 698
+LKF+AK+ DP +P Y EAL+++ RA
Sbjct: 311 LLKFLAKVNGSDPRSFPLWYEEALKDEEERA 341
Score = 127 bits (320), Expect = 4e-29
Identities = 70/214 (32%), Positives = 111/214 (51%), Gaps = 8/214 (3%)
Query: 739 SWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVY 798
S P S ++ K LVQ L K PI K IL + + FP L + A+ + V+
Sbjct: 128 SLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVF 187
Query: 799 GTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVW 858
G ++ +DP HS+ L + + D + P L+ +LS IFI G E +W
Sbjct: 188 GIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIW 247
Query: 859 AFLRGLGVQAGRKHVI--------TCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETS 910
L +G+ G +H+I T ++ + Y++ +VP SDP +YEF+WGPRA E
Sbjct: 248 EALNMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIR 307
Query: 911 KMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
KM L+++A+++ +P+ +P Y EA++DE RA
Sbjct: 308 KMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERA 341
>gi|10567820 melanoma antigen family A, 10 [Homo sapiens]
Length = 369
Score = 176 bits (445), Expect = 1e-43
Identities = 110/331 (33%), Positives = 176/331 (53%), Gaps = 33/331 (9%)
Query: 386 EGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSKCSLVLPSPRVTKASVDS 445
EGA P A + SS PS+ SSS+S + S C ++PS T V +
Sbjct: 26 EGAQA---PLAVEEDASSSTSTSSSFPSSFPSSSSS---SSSSCYPLIPS---TPEEVSA 76
Query: 446 DSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLK-----------------PQ 488
D E P P ++ C SP+ ++ + L+ S + + P+
Sbjct: 77 DDETPNP---PQSAQIA--CSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPR 131
Query: 489 DPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFEL 548
+++ V +L+QFLL K Q K PI ++E+ E ++K Y + FP + A+ + +F ++
Sbjct: 132 SEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDV 191
Query: 549 RELDPEAHTYILLNKLGPVPFEG-LEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEML 607
+E+DP H+++L+ LG + ++G L + + PK G+L++IL IF+ G E IWE L
Sbjct: 192 KEVDPTGHSFVLVTSLG-LTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEAL 250
Query: 608 WRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMK 667
MG+ I+G P++LL+ ++V + YL+YR V P YEF WGPR+H E KM
Sbjct: 251 NMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMS 310
Query: 668 ILKFMAKIYNKDPMDWPEKYNEALEEDAARA 698
+LKF+AK+ DP +P Y EAL+++ RA
Sbjct: 311 LLKFLAKVNGSDPRSFPLWYEEALKDEEERA 341
Score = 127 bits (320), Expect = 4e-29
Identities = 70/214 (32%), Positives = 111/214 (51%), Gaps = 8/214 (3%)
Query: 739 SWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVY 798
S P S ++ K LVQ L K PI K IL + + FP L + A+ + V+
Sbjct: 128 SLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVF 187
Query: 799 GTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVW 858
G ++ +DP HS+ L + + D + P L+ +LS IFI G E +W
Sbjct: 188 GIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIW 247
Query: 859 AFLRGLGVQAGRKHVI--------TCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETS 910
L +G+ G +H+I T ++ + Y++ +VP SDP +YEF+WGPRA E
Sbjct: 248 EALNMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIR 307
Query: 911 KMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
KM L+++A+++ +P+ +P Y EA++DE RA
Sbjct: 308 KMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERA 341
>gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]
Length = 739
Score = 173 bits (439), Expect = 6e-43
Identities = 143/523 (27%), Positives = 237/523 (45%), Gaps = 60/523 (11%)
Query: 185 STSVVPTPDEGPSTSVLPTPGEGPGTSVPLAA---TEGLSTSVQATPDEGPSTSVPPTAT 241
+T V D P+T +GP PLA+ ++ L TS A P E P+TS A
Sbjct: 138 ATPQVSGEDTQPTTYA--AEAQGPTPEPPLASPQTSQMLVTSKMAAP-EAPATS----AQ 190
Query: 242 EGLSTPVPPTRDEGPSTSVPATPG--------EGPSTSVLPAASDGQSISLVPTRGKGSS 293
+P EGPS++ + PST+ L GQ+ T+ G S
Sbjct: 191 SQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFL-----GQNDVFDFTQPAGVS 245
Query: 294 TSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPS 353
P T G +++ VP T G G + T + ++ T P
Sbjct: 246 GMAFPRPKRPAPAQEAATEGPSAASGVPQT-GPGREVAATRPKTTKSGKALAKTRWVEPQ 304
Query: 354 TSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGEGPS 413
V A TS+P G A+T P +
Sbjct: 305 NVV-----------AAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLD 353
Query: 414 TLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSE-GPKGAEGPIEFEVLRD--CESPNS 470
+ SS P+ V P+ R ++ S+ ++ P+ P R C P +
Sbjct: 354 DEYESSEEERETPA----VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRN 409
Query: 471 ISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFP 530
++++ ++ +L+++L++KD K PI+ ++M + +++EY FP
Sbjct: 410 VTLL-----------------QERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFP 452
Query: 531 EILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQ 590
EI+ RA LE F L+E+D E H YIL+ L ++ + P++ LL++ILG
Sbjct: 453 EIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRDSSA-RLLGKTKDTPRLSLLLVILGV 511
Query: 591 IFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVE 650
IF+NGN+A EA +WE L +MG++ R G+ ++L++ +FV Q+YL+Y+ + + P E
Sbjct: 512 IFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPE 571
Query: 651 YEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEE 693
YEF WG R+ ET+KM++L+F+A+ N+DP +W + EA+++
Sbjct: 572 YEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAVDD 614
Score = 138 bits (347), Expect = 3e-32
Identities = 81/270 (30%), Positives = 142/270 (52%), Gaps = 10/270 (3%)
Query: 685 EKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESR 744
++Y + EE A W+A + A +P S++ S P +
Sbjct: 354 DEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPR-NVTL 412
Query: 745 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV 804
L+ +A KLV+ ++ D K+PI + +L + RE + FP+++ RA TL +G L
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 805 LDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGL 864
+D H Y L R+ + + + P + L+ +L IF+ GN A E+ +W LR +
Sbjct: 473 IDKEEHLYILVCTRD-SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 865 GVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALR 916
G++ G +H +IT ++ Q+Y++ ++P+S+P +YEF+WG RAR ETSKM+ LR
Sbjct: 532 GLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLR 591
Query: 917 YVARIHRKEPQDWPQQYREAMEDEANRADV 946
++A+ ++P++W + EA++D DV
Sbjct: 592 FIAQNQNRDPREWKAHFLEAVDDAFKTMDV 621
>gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
Length = 741
Score = 173 bits (439), Expect = 6e-43
Identities = 143/523 (27%), Positives = 237/523 (45%), Gaps = 60/523 (11%)
Query: 185 STSVVPTPDEGPSTSVLPTPGEGPGTSVPLAA---TEGLSTSVQATPDEGPSTSVPPTAT 241
+T V D P+T +GP PLA+ ++ L TS A P E P+TS A
Sbjct: 138 ATPQVSGEDTQPTTYA--AEAQGPTPEPPLASPQTSQMLVTSKMAAP-EAPATS----AQ 190
Query: 242 EGLSTPVPPTRDEGPSTSVPATPG--------EGPSTSVLPAASDGQSISLVPTRGKGSS 293
+P EGPS++ + PST+ L GQ+ T+ G S
Sbjct: 191 SQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFL-----GQNDVFDFTQPAGVS 245
Query: 294 TSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPS 353
P T G +++ VP T G G + T + ++ T P
Sbjct: 246 GMAFPRPKRPAPAQEAATEGPSAASGVPQT-GPGREVAATRPKTTKSGKALAKTRWVEPQ 304
Query: 354 TSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGEGPS 413
V A TS+P G A+T P +
Sbjct: 305 NVV-----------AAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLD 353
Query: 414 TLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSE-GPKGAEGPIEFEVLRD--CESPNS 470
+ SS P+ V P+ R ++ S+ ++ P+ P R C P +
Sbjct: 354 DEYESSEEERETPA----VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRN 409
Query: 471 ISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFP 530
++++ ++ +L+++L++KD K PI+ ++M + +++EY FP
Sbjct: 410 VTLL-----------------QERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFP 452
Query: 531 EILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQ 590
EI+ RA LE F L+E+D E H YIL+ L ++ + P++ LL++ILG
Sbjct: 453 EIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRDSSA-RLLGKTKDTPRLSLLLVILGV 511
Query: 591 IFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVE 650
IF+NGN+A EA +WE L +MG++ R G+ ++L++ +FV Q+YL+Y+ + + P E
Sbjct: 512 IFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPE 571
Query: 651 YEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEE 693
YEF WG R+ ET+KM++L+F+A+ N+DP +W + EA+++
Sbjct: 572 YEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAVDD 614
Score = 138 bits (347), Expect = 3e-32
Identities = 81/270 (30%), Positives = 142/270 (52%), Gaps = 10/270 (3%)
Query: 685 EKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESR 744
++Y + EE A W+A + A +P S++ S P +
Sbjct: 354 DEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPR-NVTL 412
Query: 745 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV 804
L+ +A KLV+ ++ D K+PI + +L + RE + FP+++ RA TL +G L
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 805 LDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGL 864
+D H Y L R+ + + + P + L+ +L IF+ GN A E+ +W LR +
Sbjct: 473 IDKEEHLYILVCTRD-SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 865 GVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALR 916
G++ G +H +IT ++ Q+Y++ ++P+S+P +YEF+WG RAR ETSKM+ LR
Sbjct: 532 GLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLR 591
Query: 917 YVARIHRKEPQDWPQQYREAMEDEANRADV 946
++A+ ++P++W + EA++D DV
Sbjct: 592 FIAQNQNRDPREWKAHFLEAVDDAFKTMDV 621
>gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
Length = 741
Score = 173 bits (439), Expect = 6e-43
Identities = 143/523 (27%), Positives = 237/523 (45%), Gaps = 60/523 (11%)
Query: 185 STSVVPTPDEGPSTSVLPTPGEGPGTSVPLAA---TEGLSTSVQATPDEGPSTSVPPTAT 241
+T V D P+T +GP PLA+ ++ L TS A P E P+TS A
Sbjct: 138 ATPQVSGEDTQPTTYA--AEAQGPTPEPPLASPQTSQMLVTSKMAAP-EAPATS----AQ 190
Query: 242 EGLSTPVPPTRDEGPSTSVPATPG--------EGPSTSVLPAASDGQSISLVPTRGKGSS 293
+P EGPS++ + PST+ L GQ+ T+ G S
Sbjct: 191 SQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFL-----GQNDVFDFTQPAGVS 245
Query: 294 TSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPS 353
P T G +++ VP T G G + T + ++ T P
Sbjct: 246 GMAFPRPKRPAPAQEAATEGPSAASGVPQT-GPGREVAATRPKTTKSGKALAKTRWVEPQ 304
Query: 354 TSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGEGPS 413
V A TS+P G A+T P +
Sbjct: 305 NVV-----------AAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLD 353
Query: 414 TLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSE-GPKGAEGPIEFEVLRD--CESPNS 470
+ SS P+ V P+ R ++ S+ ++ P+ P R C P +
Sbjct: 354 DEYESSEEERETPA----VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRN 409
Query: 471 ISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFP 530
++++ ++ +L+++L++KD K PI+ ++M + +++EY FP
Sbjct: 410 VTLL-----------------QERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFP 452
Query: 531 EILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQ 590
EI+ RA LE F L+E+D E H YIL+ L ++ + P++ LL++ILG
Sbjct: 453 EIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRDSSA-RLLGKTKDTPRLSLLLVILGV 511
Query: 591 IFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVE 650
IF+NGN+A EA +WE L +MG++ R G+ ++L++ +FV Q+YL+Y+ + + P E
Sbjct: 512 IFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPE 571
Query: 651 YEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEE 693
YEF WG R+ ET+KM++L+F+A+ N+DP +W + EA+++
Sbjct: 572 YEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAVDD 614
Score = 138 bits (347), Expect = 3e-32
Identities = 81/270 (30%), Positives = 142/270 (52%), Gaps = 10/270 (3%)
Query: 685 EKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESR 744
++Y + EE A W+A + A +P S++ S P +
Sbjct: 354 DEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPR-NVTL 412
Query: 745 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV 804
L+ +A KLV+ ++ D K+PI + +L + RE + FP+++ RA TL +G L
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 805 LDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGL 864
+D H Y L R+ + + + P + L+ +L IF+ GN A E+ +W LR +
Sbjct: 473 IDKEEHLYILVCTRD-SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 865 GVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALR 916
G++ G +H +IT ++ Q+Y++ ++P+S+P +YEF+WG RAR ETSKM+ LR
Sbjct: 532 GLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLR 591
Query: 917 YVARIHRKEPQDWPQQYREAMEDEANRADV 946
++A+ ++P++W + EA++D DV
Sbjct: 592 FIAQNQNRDPREWKAHFLEAVDDAFKTMDV 621
>gi|149274614 melanoma antigen family D, 4 [Homo sapiens]
Length = 739
Score = 173 bits (439), Expect = 6e-43
Identities = 143/523 (27%), Positives = 237/523 (45%), Gaps = 60/523 (11%)
Query: 185 STSVVPTPDEGPSTSVLPTPGEGPGTSVPLAA---TEGLSTSVQATPDEGPSTSVPPTAT 241
+T V D P+T +GP PLA+ ++ L TS A P E P+TS A
Sbjct: 138 ATPQVSGEDTQPTTYA--AEAQGPTPEPPLASPQTSQMLVTSKMAAP-EAPATS----AQ 190
Query: 242 EGLSTPVPPTRDEGPSTSVPATPG--------EGPSTSVLPAASDGQSISLVPTRGKGSS 293
+P EGPS++ + PST+ L GQ+ T+ G S
Sbjct: 191 SQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFL-----GQNDVFDFTQPAGVS 245
Query: 294 TSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPS 353
P T G +++ VP T G G + T + ++ T P
Sbjct: 246 GMAFPRPKRPAPAQEAATEGPSAASGVPQT-GPGREVAATRPKTTKSGKALAKTRWVEPQ 304
Query: 354 TSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGEGPS 413
V A TS+P G A+T P +
Sbjct: 305 NVV-----------AAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLD 353
Query: 414 TLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSE-GPKGAEGPIEFEVLRD--CESPNS 470
+ SS P+ V P+ R ++ S+ ++ P+ P R C P +
Sbjct: 354 DEYESSEEERETPA----VPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRN 409
Query: 471 ISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFP 530
++++ ++ +L+++L++KD K PI+ ++M + +++EY FP
Sbjct: 410 VTLL-----------------QERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFP 452
Query: 531 EILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQ 590
EI+ RA LE F L+E+D E H YIL+ L ++ + P++ LL++ILG
Sbjct: 453 EIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRDSSA-RLLGKTKDTPRLSLLLVILGV 511
Query: 591 IFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVE 650
IF+NGN+A EA +WE L +MG++ R G+ ++L++ +FV Q+YL+Y+ + + P E
Sbjct: 512 IFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPE 571
Query: 651 YEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEE 693
YEF WG R+ ET+KM++L+F+A+ N+DP +W + EA+++
Sbjct: 572 YEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAVDD 614
Score = 138 bits (347), Expect = 3e-32
Identities = 81/270 (30%), Positives = 142/270 (52%), Gaps = 10/270 (3%)
Query: 685 EKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESR 744
++Y + EE A W+A + A +P S++ S P +
Sbjct: 354 DEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPR-NVTL 412
Query: 745 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV 804
L+ +A KLV+ ++ D K+PI + +L + RE + FP+++ RA TL +G L
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 805 LDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGL 864
+D H Y L R+ + + + P + L+ +L IF+ GN A E+ +W LR +
Sbjct: 473 IDKEEHLYILVCTRD-SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 865 GVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALR 916
G++ G +H +IT ++ Q+Y++ ++P+S+P +YEF+WG RAR ETSKM+ LR
Sbjct: 532 GLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLR 591
Query: 917 YVARIHRKEPQDWPQQYREAMEDEANRADV 946
++A+ ++P++W + EA++D DV
Sbjct: 592 FIAQNQNRDPREWKAHFLEAVDDAFKTMDV 621
>gi|222418639 melanoma antigen family B, 2 [Homo sapiens]
Length = 319
Score = 172 bits (437), Expect = 1e-42
Identities = 98/285 (34%), Positives = 157/285 (55%), Gaps = 18/285 (6%)
Query: 411 GPSTLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNS 470
G + S +A + + P + P+ A+ S ++ KGA+ + +
Sbjct: 47 GGAASSSPAAGIPQEPQRA----PTTAAAAAAGVSSTKSKKGAKSH---------QGEKN 93
Query: 471 ISIMGLNTSRVAITLKP-QDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQF 529
S +TS T P +DP+ + L+QFLL K + K + + EM + + K +R F
Sbjct: 94 ASSSQASTS----TKSPSEDPLTRKSGSLVQFLLYKYKIKKSVTKGEMLKIVGKRFREHF 149
Query: 530 PEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILG 589
PEIL++A+ L +F EL +++P HTY ++K+ E L S + P+ LLM +LG
Sbjct: 150 PEILKKASEGLSVVFGLELNKVNPNGHTYTFIDKVDLTDEESLLSSWDFPRRKLLMPLLG 209
Query: 590 QIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPV 649
IFLNGN A E EIWE L +GV S+FG P +L++ + V ++YL+Y+ V P
Sbjct: 210 VIFLNGNSATEEEIWEFLNMLGVYDGEEHSVFGEPWKLITKDLVQEKYLEYKQVPSSDPP 269
Query: 650 EYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEED 694
++F WGPR++ ET+KMK+L+F+AK+ P +P Y EAL+++
Sbjct: 270 RFQFLWGPRAYAETSKMKVLEFLAKVNGTTPCAFPTHYEEALKDE 314
Score = 143 bits (361), Expect = 7e-34
Identities = 76/224 (33%), Positives = 125/224 (55%), Gaps = 8/224 (3%)
Query: 725 DSEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFP 784
+ SS + + S E L K+ LVQ L K + K +L +G+ + FP
Sbjct: 91 EKNASSSQASTSTKSPSEDPLTRKSGSLVQFLLYKYKIKKSVTKGEMLKIVGKRFREHFP 150
Query: 785 DLLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSF 844
++L +A+ L+ V+G EL ++P H+YT ++ ++ + E ++ S + P LM +L
Sbjct: 151 EILKKASEGLSVVFGLELNKVNPNGHTYTFIDKVDLTDEESLLSSWDFPRRKLLMPLLGV 210
Query: 845 IFIMGNHARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQ 896
IF+ GN A E +W FL LGV G +H +IT + ++Y++ +VP SDP +
Sbjct: 211 IFLNGNSATEEEIWEFLNMLGVYDGEEHSVFGEPWKLITKDLVQEKYLEYKQVPSSDPPR 270
Query: 897 YEFVWGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDE 940
++F+WGPRA ETSKMK L ++A+++ P +P Y EA++DE
Sbjct: 271 FQFLWGPRAYAETSKMKVLEFLAKVNGTTPCAFPTHYEEALKDE 314
>gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo
sapiens]
Length = 457
Score = 172 bits (437), Expect = 1e-42
Identities = 102/269 (37%), Positives = 152/269 (56%), Gaps = 18/269 (6%)
Query: 434 PSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLKPQDPMEQ 493
PS + S+ S EG KG +G ESPNS G ++S +D +
Sbjct: 189 PSSPASAVSLTSSDEGAKGQKG----------ESPNSFH--GPSSSEST----GRDLLNT 232
Query: 494 NVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELDP 553
EL+QFLL K K PI M + I ++Y+ FPEILRR+ ++E +F L+E+DP
Sbjct: 233 KTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYLKEMDP 292
Query: 554 EAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQ 613
+Y+L+ KL L + P GLLM++L IF++GN+A E E+WE L +G+
Sbjct: 293 SRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLNALGMY 352
Query: 614 RERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMA 673
+ R+ I+G P+ L++ + V + YL+Y+ V P YEF WGPR+ ET+KMK+L+F+A
Sbjct: 353 KGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMKVLEFVA 412
Query: 674 KIYNKDPMDWPEKYNEAL--EEDAARAFA 700
K+ + + +Y EAL EE+ ARA A
Sbjct: 413 KLNDTVASTYKSRYEEALREEEEQARARA 441
Score = 138 bits (347), Expect = 3e-32
Identities = 92/281 (32%), Positives = 140/281 (49%), Gaps = 25/281 (8%)
Query: 689 EALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKY--------APHSW 740
E L ++ A Q+ P+ P + A+ SP S VS SS +P+S+
Sbjct: 157 EKLPSSSSPACQSPPQSFPNAGIPQESQRASYPSSPASAVSLTSSDEGAKGQKGESPNSF 216
Query: 741 --PESR-------LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAA 791
P S L +K +LVQ L K PI ++ +L I R+ + FP++L R+
Sbjct: 217 HGPSSSESTGRDLLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRST 276
Query: 792 RTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNH 851
+ V+G L +DP SY L + + + D P + LM +LS IF+ GN
Sbjct: 277 ENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNR 336
Query: 852 ARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGP 903
A E +W L LG+ GRKH ++T + + Y++ +VP SDP +YEF+WGP
Sbjct: 337 ATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGP 396
Query: 904 RARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
RAR ETSKMK L +VA+++ + +Y EA+ +E +A
Sbjct: 397 RARAETSKMKVLEFVAKLNDTVASTYKSRYEEALREEEEQA 437
>gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo
sapiens]
Length = 457
Score = 172 bits (437), Expect = 1e-42
Identities = 102/269 (37%), Positives = 152/269 (56%), Gaps = 18/269 (6%)
Query: 434 PSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLKPQDPMEQ 493
PS + S+ S EG KG +G ESPNS G ++S +D +
Sbjct: 189 PSSPASAVSLTSSDEGAKGQKG----------ESPNSFH--GPSSSEST----GRDLLNT 232
Query: 494 NVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELDP 553
EL+QFLL K K PI M + I ++Y+ FPEILRR+ ++E +F L+E+DP
Sbjct: 233 KTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYLKEMDP 292
Query: 554 EAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQ 613
+Y+L+ KL L + P GLLM++L IF++GN+A E E+WE L +G+
Sbjct: 293 SRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLNALGMY 352
Query: 614 RERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMA 673
+ R+ I+G P+ L++ + V + YL+Y+ V P YEF WGPR+ ET+KMK+L+F+A
Sbjct: 353 KGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMKVLEFVA 412
Query: 674 KIYNKDPMDWPEKYNEAL--EEDAARAFA 700
K+ + + +Y EAL EE+ ARA A
Sbjct: 413 KLNDTVASTYKSRYEEALREEEEQARARA 441
Score = 138 bits (347), Expect = 3e-32
Identities = 92/281 (32%), Positives = 140/281 (49%), Gaps = 25/281 (8%)
Query: 689 EALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKY--------APHSW 740
E L ++ A Q+ P+ P + A+ SP S VS SS +P+S+
Sbjct: 157 EKLPSSSSPACQSPPQSFPNAGIPQESQRASYPSSPASAVSLTSSDEGAKGQKGESPNSF 216
Query: 741 --PESR-------LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAA 791
P S L +K +LVQ L K PI ++ +L I R+ + FP++L R+
Sbjct: 217 HGPSSSESTGRDLLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRST 276
Query: 792 RTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNH 851
+ V+G L +DP SY L + + + D P + LM +LS IF+ GN
Sbjct: 277 ENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNR 336
Query: 852 ARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGP 903
A E +W L LG+ GRKH ++T + + Y++ +VP SDP +YEF+WGP
Sbjct: 337 ATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGP 396
Query: 904 RARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
RAR ETSKMK L +VA+++ + +Y EA+ +E +A
Sbjct: 397 RARAETSKMKVLEFVAKLNDTVASTYKSRYEEALREEEEQA 437
>gi|169216802 PREDICTED: melanoma antigen family B, 17 [Homo
sapiens]
Length = 457
Score = 172 bits (437), Expect = 1e-42
Identities = 102/269 (37%), Positives = 152/269 (56%), Gaps = 18/269 (6%)
Query: 434 PSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRVAITLKPQDPMEQ 493
PS + S+ S EG KG +G ESPNS G ++S +D +
Sbjct: 189 PSSPASAVSLTSSDEGAKGQKG----------ESPNSFH--GPSSSEST----GRDLLNT 232
Query: 494 NVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELDP 553
EL+QFLL K K PI M + I ++Y+ FPEILRR+ ++E +F L+E+DP
Sbjct: 233 KTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYLKEMDP 292
Query: 554 EAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQ 613
+Y+L+ KL L + P GLLM++L IF++GN+A E E+WE L +G+
Sbjct: 293 SRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLNALGMY 352
Query: 614 RERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMA 673
+ R+ I+G P+ L++ + V + YL+Y+ V P YEF WGPR+ ET+KMK+L+F+A
Sbjct: 353 KGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMKVLEFVA 412
Query: 674 KIYNKDPMDWPEKYNEAL--EEDAARAFA 700
K+ + + +Y EAL EE+ ARA A
Sbjct: 413 KLNDTVASTYKSRYEEALREEEEQARARA 441
Score = 138 bits (347), Expect = 3e-32
Identities = 92/281 (32%), Positives = 140/281 (49%), Gaps = 25/281 (8%)
Query: 689 EALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKY--------APHSW 740
E L ++ A Q+ P+ P + A+ SP S VS SS +P+S+
Sbjct: 157 EKLPSSSSPACQSPPQSFPNAGIPQESQRASYPSSPASAVSLTSSDEGAKGQKGESPNSF 216
Query: 741 --PESR-------LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAA 791
P S L +K +LVQ L K PI ++ +L I R+ + FP++L R+
Sbjct: 217 HGPSSSESTGRDLLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRST 276
Query: 792 RTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNH 851
+ V+G L +DP SY L + + + D P + LM +LS IF+ GN
Sbjct: 277 ENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNR 336
Query: 852 ARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGP 903
A E +W L LG+ GRKH ++T + + Y++ +VP SDP +YEF+WGP
Sbjct: 337 ATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGP 396
Query: 904 RARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944
RAR ETSKMK L +VA+++ + +Y EA+ +E +A
Sbjct: 397 RARAETSKMKVLEFVAKLNDTVASTYKSRYEEALREEEEQA 437
>gi|29171711 melanoma antigen family B, 1 [Homo sapiens]
Length = 347
Score = 169 bits (429), Expect = 9e-42
Identities = 100/299 (33%), Positives = 160/299 (53%), Gaps = 22/299 (7%)
Query: 400 PGSSVLPNPGEGPSTLFSSSASVDRNPSKCSLVLPSPRVTKASVDSDSEGPKGAEGPIEF 459
P SS P G+ P++ S +A + + P P T A+ S +E +GA+
Sbjct: 39 PSSS--PVLGDTPTS--SPAAGIPQKPQGAP-----PTTTAAAAVSCTESDEGAK----- 84
Query: 460 EVLRDCESPNSISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMRE 519
C+ + S TS + +DP+ L+ F+L K + + PI +++M +
Sbjct: 85 -----CQGEENASFSQATTSTESSV---KDPVAWEAGMLMHFILRKYKMREPIMKADMLK 136
Query: 520 YIVKEYRNQFPEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGP 579
+ ++Y++ F EIL A+ LE +F +L+E +P HTY L++KL L + P
Sbjct: 137 VVDEKYKDHFTEILNGASRRLELVFGLDLKEDNPSGHTYTLVSKLNLTNDGNLSNDWDFP 196
Query: 580 KMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLD 639
+ GLLM +LG IFL GN A E EIW+ + +G I+G P++ ++ + V ++YL
Sbjct: 197 RNGLLMPLLGVIFLKGNSATEEEIWKFMNVLGAYDGEEHLIYGEPRKFITQDLVQEKYLK 256
Query: 640 YRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEEDAARA 698
Y V + P Y+F WGPR++ ETTKMK+L+F+AK+ P D+P Y EAL ++ RA
Sbjct: 257 YEQVPNSDPPRYQFLWGPRAYAETTKMKVLEFLAKMNGATPRDFPSHYEEALRDEEERA 315
Score = 135 bits (340), Expect = 2e-31
Identities = 76/226 (33%), Positives = 121/226 (53%), Gaps = 15/226 (6%)
Query: 729 SSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLN 788
S+ SS P +W +A L+ L + PI K +L + + F ++LN
Sbjct: 99 STESSVKDPVAW-------EAGMLMHFILRKYKMREPIMKADMLKVVDEKYKDHFTEILN 151
Query: 789 RAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIM 848
A+R L V+G +L +P H+YTL ++ + + + + P N LM +L IF+
Sbjct: 152 GASRRLELVFGLDLKEDNPSGHTYTLVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLK 211
Query: 849 GNHARESAVWAFLRGLGVQAGRKHVI--------TCRYLSQRYIDSLRVPDSDPVQYEFV 900
GN A E +W F+ LG G +H+I T + ++Y+ +VP+SDP +Y+F+
Sbjct: 212 GNSATEEEIWKFMNVLGAYDGEEHLIYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFL 271
Query: 901 WGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRADV 946
WGPRA ET+KMK L ++A+++ P+D+P Y EA+ DE RA V
Sbjct: 272 WGPRAYAETTKMKVLEFLAKMNGATPRDFPSHYEEALRDEEERAQV 317
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,028,636
Number of Sequences: 37866
Number of extensions: 2886726
Number of successful extensions: 37053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 338
Number of HSP's successfully gapped in prelim test: 1932
Number of HSP's that attempted gapping in prelim test: 13284
Number of HSP's gapped (non-prelim): 9992
length of query: 957
length of database: 18,247,518
effective HSP length: 112
effective length of query: 845
effective length of database: 14,006,526
effective search space: 11835514470
effective search space used: 11835514470
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.