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Search of human proteins with 20127553
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20127553 anaphase-promoting complex subunit 5 isoform a
[Homo sapiens]
(755 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20127553 anaphase-promoting complex subunit 5 isoform a [Homo... 1478 0.0
gi|213385323 anaphase-promoting complex subunit 5 isoform b [Hom... 1254 0.0
gi|21735569 claspin [Homo sapiens] 35 0.34
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 34 0.57
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 33 0.75
gi|130980075 centromere protein J [Homo sapiens] 33 0.98
gi|38488692 SH3 domain and tetratricopeptide repeats 2 [Homo sap... 33 0.98
gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens] 33 0.98
gi|51477718 TATA box binding protein-associated factor, RNA poly... 33 1.3
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 32 1.7
gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo sap... 32 1.7
gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo sap... 32 1.7
gi|110347427 ubiquitin specific protease 34 [Homo sapiens] 32 1.7
gi|110611919 UDP glucuronosyltransferase 2 family, polypeptide A... 32 2.2
gi|4758980 pituitary tumor-transforming protein 1 [Homo sapiens] 32 2.8
gi|148747864 JAW1-related protein isoform a [Homo sapiens] 32 2.8
gi|154091334 JAW1-related protein isoform c [Homo sapiens] 32 2.8
gi|154091332 JAW1-related protein isoform b [Homo sapiens] 32 2.8
gi|148728182 JAW1-related protein isoform b [Homo sapiens] 32 2.8
gi|217416374 hypothetical protein LOC92749 [Homo sapiens] 32 2.8
gi|21735548 centrosomal protein 2 [Homo sapiens] 31 3.7
gi|62899047 RAD50 interactor 1 [Homo sapiens] 31 3.7
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 31 3.7
gi|11034845 Regulation of nuclear pre-mRNA domain containing 1B ... 31 4.9
gi|7656849 acyl-Coenzyme A dehydrogenase family, member 8 [Homo ... 31 4.9
gi|226693318 adenosine deaminase-like isoform 1 [Homo sapiens] 30 6.3
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 30 6.3
gi|21359945 chromosome condensation protein G [Homo sapiens] 30 6.3
gi|68077164 Yeast Sps1/Ste20-related kinase 4 isoform 1 [Homo sa... 30 6.3
gi|221139761 zinc finger protein 853 [Homo sapiens] 30 8.3
>gi|20127553 anaphase-promoting complex subunit 5 isoform a [Homo
sapiens]
Length = 755
Score = 1478 bits (3827), Expect = 0.0
Identities = 755/755 (100%), Positives = 755/755 (100%)
Query: 1 MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRL 60
MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRL
Sbjct: 1 MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRL 60
Query: 61 NQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFS 120
NQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFS
Sbjct: 61 NQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFS 120
Query: 121 GTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR 180
GTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR
Sbjct: 121 GTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR 180
Query: 181 DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKEL 240
DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKEL
Sbjct: 181 DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKEL 240
Query: 241 NNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSL 300
NNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSL
Sbjct: 241 NNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSL 300
Query: 301 RYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL 360
RYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL
Sbjct: 301 RYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL 360
Query: 361 LEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDI 420
LEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDI
Sbjct: 361 LEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDI 420
Query: 421 SIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQ 480
SIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQ
Sbjct: 421 SIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQ 480
Query: 481 GCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNS 540
GCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNS
Sbjct: 481 GCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNS 540
Query: 541 IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIA 600
IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIA
Sbjct: 541 IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIA 600
Query: 601 LPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDK 660
LPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDK
Sbjct: 601 LPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDK 660
Query: 661 GRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARL 720
GRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARL
Sbjct: 661 GRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARL 720
Query: 721 YHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL 755
YHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL
Sbjct: 721 YHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL 755
>gi|213385323 anaphase-promoting complex subunit 5 isoform b [Homo
sapiens]
Length = 643
Score = 1254 bits (3244), Expect = 0.0
Identities = 643/656 (98%), Positives = 643/656 (98%), Gaps = 13/656 (1%)
Query: 100 MAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQ 159
MAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQ
Sbjct: 1 MAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQ 60
Query: 160 QYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQ 219
QYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQ
Sbjct: 61 QYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQ 120
Query: 220 ASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFD 279
ASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFD
Sbjct: 121 ASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFD 180
Query: 280 RLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVC 339
RLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVC
Sbjct: 181 RLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVC 240
Query: 340 LQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLM 399
LQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLP RAFAGKTANKLM
Sbjct: 241 LQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLP-------------RAFAGKTANKLM 287
Query: 400 DALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQ 459
DALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQ
Sbjct: 288 DALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQ 347
Query: 460 QNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRA 519
QNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRA
Sbjct: 348 QNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRA 407
Query: 520 MNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEM 579
MNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEM
Sbjct: 408 MNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEM 467
Query: 580 VISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQ 639
VISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQ
Sbjct: 468 VISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQ 527
Query: 640 ALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKN 699
ALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKN
Sbjct: 528 ALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKN 587
Query: 700 YFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL 755
YFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL
Sbjct: 588 YFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL 643
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 34.7 bits (78), Expect = 0.34
Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 21/139 (15%)
Query: 166 EKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPL---SQKQAEFFLSQQASL 222
E++ E+ +M S ++GE K+EKEE + + EEE +Q+ AEF LS +
Sbjct: 629 EEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIE 688
Query: 223 LKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLI 282
K+++ + KE N+ + + L V SS +LL + D
Sbjct: 689 TKDEK-------EMDKENND--------GSSEIGKAVGFLSVPKSLSSDSTLLLFKDSSS 733
Query: 283 LTG---AESKSNGEEGYGR 298
G E KS +E G+
Sbjct: 734 KMGYFPTEEKSETDENSGK 752
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 33.9 bits (76), Expect = 0.57
Identities = 97/540 (17%), Positives = 202/540 (37%), Gaps = 65/540 (12%)
Query: 64 LLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLS---DSFS 120
L +++ D+ L + + ++E N ++ ++KL A+ +L + ++ +++ +
Sbjct: 64 LKDIIRQKDVQLQQKDEALQEERKAADNKIK-KLKLHAKAKLTSLNKYIEEMKAQGGTVL 122
Query: 121 GTEPEVH-------KTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDA 173
TEP+ K+S M + K + +L + LQ + + +
Sbjct: 123 PTEPQSEEQLSKHDKSSTE----EEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQS 178
Query: 174 DMELTSRDEGERKMEKEELDVSVREEEVS-------CSGPLSQKQAEFFLSQQASLLKND 226
E+ +++++++E +S + ++S + +K A F Q L +++
Sbjct: 179 STEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARF--ETQVRLHEDE 236
Query: 227 ETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGA 286
+ +T A ++ E+ L+ E H S + +V D+ + ++++
Sbjct: 237 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQL 296
Query: 287 ESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSW 346
+ E +LR N ++ L+ A R N + H L
Sbjct: 297 QQM----EAEHNTLR----NTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQ 348
Query: 347 LYVLGQKRSD---SYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALK 403
GQ +++ Y LE K + ++ SL G+ DALK
Sbjct: 349 FEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSL---------QKTGQELQSACDALK 399
Query: 404 D--SDLLHWKH--------SLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEA 453
D S LL K+ ++ +L D + I + R + LQQ + + +
Sbjct: 400 DQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNR--LPLQQHETASQTSFPDV 457
Query: 454 VNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQK 513
N G Q E+ A + EL E+G +S L+ LK S L ++
Sbjct: 458 YNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRT 517
Query: 514 IQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQK 573
+ DR +++ ++ + N ++ +N S+ HK L LL+ ++
Sbjct: 518 GEADREVSE---------ISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKE 568
Score = 30.0 bits (66), Expect = 8.3
Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 17/148 (11%)
Query: 102 EGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQ- 160
E +LK+ E+ +DL SF+ + E S + K+S SQ+ + TALQ+
Sbjct: 2573 EEKLKESEEANEDLRRSFNALQEEKQDLS--------KEIESLKVSISQLTRQVTALQEE 2624
Query: 161 -----YFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFF 215
Y + K E + +R E EE V V++E G + K +
Sbjct: 2625 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKEL 2684
Query: 216 --LSQQASLLKND-ETKALTPASLQKEL 240
L A +++N+ ET A L ++L
Sbjct: 2685 KHLHHDAGIMRNETETAEERVAELARDL 2712
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 33.5 bits (75), Expect = 0.75
Identities = 39/174 (22%), Positives = 77/174 (44%), Gaps = 28/174 (16%)
Query: 76 SKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLF 135
+K +L+EE+ + + S ++ KL L +ME +DL +G E E K
Sbjct: 1894 NKPTELLEENTEEKSKSHLVQPKL-----LSNMEAQHNDLEFKLAGAEREKQKLG----- 1943
Query: 136 LRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDV- 194
++ +L L+ + ++ +E E E + K E+E+L++
Sbjct: 1944 -------------KEIVRLQKDLRM-LRKEHQQELEILKKEYDQEREEKIKQEQEDLELK 1989
Query: 195 ---SVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLK 245
++++ + L+QK+ E ++ + ++ K E +A S Q+E N LLK
Sbjct: 1990 HNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLK 2043
>gi|130980075 centromere protein J [Homo sapiens]
Length = 1338
Score = 33.1 bits (74), Expect = 0.98
Identities = 25/93 (26%), Positives = 49/93 (52%), Gaps = 13/93 (13%)
Query: 155 YTALQQYFQNG-EKKTVEDADMELTSRDEGERKMEKEELD--VSVREEEVSCSGPLSQKQ 211
+T + FQ G E K V + + TS D+ KM++++L +++ +E+ P+ +K
Sbjct: 385 FTNAKSKFQKGKESKLVTN---QSTSEDQPLFKMDRQQLQRKTALKNKELCADNPILKKD 441
Query: 212 AE-------FFLSQQASLLKNDETKALTPASLQ 237
++ LSQ+ +LK K+L+P+ L+
Sbjct: 442 SKARTKSGSVTLSQKPKMLKCSNRKSLSPSGLK 474
>gi|38488692 SH3 domain and tetratricopeptide repeats 2 [Homo
sapiens]
Length = 1288
Score = 33.1 bits (74), Expect = 0.98
Identities = 27/90 (30%), Positives = 49/90 (54%), Gaps = 5/90 (5%)
Query: 563 LLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASE 622
+L++ L C++L + ++ L ++++Y SP A+ L QAL L + Q + E
Sbjct: 739 MLRQALAACEELADRSTQRALCLILSKVYLEHRSPDGAIHYLSQALVLGQLLGEQE-SFE 797
Query: 623 TVLNLAFAQLILGIPEQALSLLHMAIEPIL 652
+ L LA+A L+ ++AL +L EP+L
Sbjct: 798 SSLCLAWAYLLASQAKKALDVL----EPLL 823
>gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens]
Length = 1316
Score = 33.1 bits (74), Expect = 0.98
Identities = 161/710 (22%), Positives = 258/710 (36%), Gaps = 170/710 (23%)
Query: 81 LIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMI 140
L+++S A +Q + EG+++ ++L ++ EP+ + ++
Sbjct: 239 LLQDSQNVEALRMQALYYVCREGDIEKASTKLENLGNTLDAMEPQNAQ------LFYNIT 292
Query: 141 LAYSKL-SFSQVF--KLYTALQQYF----QNGEKKTVEDADMELTSRDEGERKMEK---- 189
LA+S+ SQ+ K+ T L++ F Q E T M L R + K K
Sbjct: 293 LAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVKEALKWYKTAMT 352
Query: 190 -EELDVSVREEEVSCS---GPL--SQKQAEFFLSQQASLLKNDE------TKALTPASLQ 237
+E VS + C G L + +Q EF Q S+ K+ E A+ Q
Sbjct: 353 LDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLHAVLAMKKNKRQ 412
Query: 238 KELNNLL----------------------KFNPDFAEAHYLSYLNNLRVQDVFSSTHSLL 275
+E+ NLL K NPDF + YL+ +Q +S L
Sbjct: 413 EEVINLLNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPMQP--ASPGQPL 470
Query: 276 HYFDRLILTGAESKSNGEEGYGRSL------RYAALNLAALHCRFGH-------YQQAEL 322
R ++ E+ G +++ +Y + ++ A H Y A L
Sbjct: 471 CPLLRRCISVLETVVRTVPGLLQTVFLIAKVKYLSGDIEAAFNNLQHCLEHNPSYADAHL 530
Query: 323 AL------QEAIRIAQESNDHVCLQHCLSW--------LYVLGQKRSDSYVLLEHSVKKA 368
L QE +++ +S L+ CLS+ LY L + +S + K
Sbjct: 531 LLAQVYLSQEKVKLCSQS-----LELCLSYDFKVRDYPLYHLIKAQSQKKMGEIADAIKT 585
Query: 369 VHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAI 428
+H + SL + T +K D + D H ELID+
Sbjct: 586 LHMAM---------SLPGMKRIGASTKSK--DRKTEVDTSHRLSIFLELIDVH------- 627
Query: 429 WRLYGR---STMALQQAQMLLSMNSLEA------VNAGVQQNNTESFAVALCHLAELHAE 479
RL G +T LQ A S S E + + Q + E AL L + AE
Sbjct: 628 -RLNGEQHEATKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIER---ALSILQNVTAE 683
Query: 480 QGCFAAASE-----VLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTG 534
Q F A E LKH K++ L++ C ++I +R N + L+ G
Sbjct: 684 QPYFIEAREKMADIYLKHRKDKM--------LYITCFREIA-ERMANPRSF-----LLLG 729
Query: 535 ITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRS 594
+N +E QA NQ + L K+ K N M I+ Y+ +
Sbjct: 730 DAYMNILEPEEAIVAYEQALNQNPKDGTLASKMGKALIKTHNYSMAIT--------YYEA 781
Query: 595 SSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILAD 654
AL ++ L Y +E +L L + + + AL A EP+
Sbjct: 782 ------------ALKTGQKNYLCYDLAELLLKLKWYDKAEKVLQHAL-----AHEPVNEL 824
Query: 655 GAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKV 704
A+++ GR L+AK K E L AI L +A+ A+V
Sbjct: 825 SALMEDGRCQVLLAKVY----------SKMEKLGDAITALQQARELQARV 864
>gi|51477718 TATA box binding protein-associated factor, RNA
polymerase II, Q [Homo sapiens]
Length = 462
Score = 32.7 bits (73), Expect = 1.3
Identities = 33/154 (21%), Positives = 63/154 (40%), Gaps = 14/154 (9%)
Query: 87 PQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKL 146
P + N V+ ++ AE E +D GT+ + S+ G + + ++ +
Sbjct: 259 PDVENEVKRLLRSDAEAVSTRWEVIAED------GTKEIESQGSIPGFLISSGMSSHKQG 312
Query: 147 SFSQVFKLYTALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGP 206
S Y L++ F + +D D + DE E + E E+ D EEE CS
Sbjct: 313 HTSSE---YDMLREMFSDSRSNNDDDEDED----DEDEDEDEDEDEDEDKEEEEEDCSEE 365
Query: 207 LSQKQAEFFLSQQASLLKNDETKALTPASLQKEL 240
++Q + + N+ T ++ +QK++
Sbjct: 366 YLERQLQAEFIESGQYRANEGTSSIV-MEIQKQI 398
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 32.3 bits (72), Expect = 1.7
Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 10/55 (18%)
Query: 160 QYFQNGEKKTVEDADMELTSRDEGERKME---------KEELDVSVREEEVSCSG 205
QYFQN +T+ D D+ L E + + E KE+L+ + EEEVS G
Sbjct: 89 QYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLE-DLEEEEVSDMG 142
>gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo
sapiens]
Length = 594
Score = 32.3 bits (72), Expect = 1.7
Identities = 47/177 (26%), Positives = 72/177 (40%), Gaps = 34/177 (19%)
Query: 58 RRLNQLLLPLLQGPDITLSK-----LYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFF 112
R L + L P L P +++ + L+EE P + SV + L E +L +
Sbjct: 152 RELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNTAARIG 211
Query: 113 DDLSDSFSGTEPEVHKT-SVVG------LFLRHMILAYSKLSFSQVFKLYTALQQYFQNG 165
L S E K +++G L+LRH + +L LQ Y +
Sbjct: 212 QSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDEL-----------LQLYSDSD 260
Query: 166 EKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASL 222
E ED D E +E E K +EE + EE++ C+ P A +SQ+A L
Sbjct: 261 E----EDEDEE----EEEEEKEAEEEQEEEEAEEDLQCAHPC---DAPKLISQEALL 306
>gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
sapiens]
Length = 619
Score = 32.3 bits (72), Expect = 1.7
Identities = 47/177 (26%), Positives = 72/177 (40%), Gaps = 34/177 (19%)
Query: 58 RRLNQLLLPLLQGPDITLSK-----LYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFF 112
R L + L P L P +++ + L+EE P + SV + L E +L +
Sbjct: 152 RELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNTAARIG 211
Query: 113 DDLSDSFSGTEPEVHKT-SVVG------LFLRHMILAYSKLSFSQVFKLYTALQQYFQNG 165
L S E K +++G L+LRH + +L LQ Y +
Sbjct: 212 QSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDEL-----------LQLYSDSD 260
Query: 166 EKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASL 222
E ED D E +E E K +EE + EE++ C+ P A +SQ+A L
Sbjct: 261 E----EDEDEE----EEEEEKEAEEEQEEEEAEEDLQCAHPC---DAPKLISQEALL 306
>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
Length = 3546
Score = 32.3 bits (72), Expect = 1.7
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 6/105 (5%)
Query: 103 GELKDMEQFFDDLSDSFSGTEPEVHKT--SVVGLFLRHMILAYSKLSFSQVFKLYTALQQ 160
GE KDM +FF DL PE+ T S+ G + + +++ SQ + + ++
Sbjct: 1974 GEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR- 2032
Query: 161 YFQNGEKKTVEDADMELTSRD--EGERKMEKEELDVSVREEEVSC 203
Q + K + ++ E+T +D EG+ VR E+ +C
Sbjct: 2033 -CQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRAC 2076
>gi|110611919 UDP glucuronosyltransferase 2 family, polypeptide A1
[Homo sapiens]
Length = 527
Score = 32.0 bits (71), Expect = 2.2
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 483 FAAASEVLKHL-KERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSI 541
F+ AS V KH K +PP+ A L L DQ DR N YHL D + T S
Sbjct: 173 FSPASTVEKHCGKVPYPPSYVPAVLSELTDQMSFTDRIRNFISYHLQDYMFE--TLWKSW 230
Query: 542 EGVYRKAV 549
+ Y KA+
Sbjct: 231 DSYYSKAL 238
>gi|4758980 pituitary tumor-transforming protein 1 [Homo sapiens]
Length = 202
Score = 31.6 bits (70), Expect = 2.8
Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 10/70 (14%)
Query: 198 EEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPAS--LQKELNNLLKFNP------D 249
E+ V GPL QKQ F S + K + K+ PAS E+ FNP D
Sbjct: 72 EKSVKTKGPLKQKQPSF--SAKKMTEKTVKAKSSVPASDDAYPEIEKFFPFNPLDFESFD 129
Query: 250 FAEAHYLSYL 259
E H +++L
Sbjct: 130 LPEEHQIAHL 139
>gi|148747864 JAW1-related protein isoform a [Homo sapiens]
Length = 903
Score = 31.6 bits (70), Expect = 2.8
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 157 ALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAE 213
A + FQ G KKT E D++ +E E+K E E V E E GP S K E
Sbjct: 774 AYSKGFQEGLKKTKELQDLK---EEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEE 827
>gi|154091334 JAW1-related protein isoform c [Homo sapiens]
Length = 597
Score = 31.6 bits (70), Expect = 2.8
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 157 ALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAE 213
A + FQ G KKT E D++ +E E+K E E V E E GP S K E
Sbjct: 468 AYSKGFQEGLKKTKELQDLK---EEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEE 521
>gi|154091332 JAW1-related protein isoform b [Homo sapiens]
Length = 821
Score = 31.6 bits (70), Expect = 2.8
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 157 ALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAE 213
A + FQ G KKT E D++ +E E+K E E V E E GP S K E
Sbjct: 692 AYSKGFQEGLKKTKELQDLK---EEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEE 745
>gi|148728182 JAW1-related protein isoform b [Homo sapiens]
Length = 821
Score = 31.6 bits (70), Expect = 2.8
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 157 ALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAE 213
A + FQ G KKT E D++ +E E+K E E V E E GP S K E
Sbjct: 692 AYSKGFQEGLKKTKELQDLK---EEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEE 745
>gi|217416374 hypothetical protein LOC92749 [Homo sapiens]
Length = 740
Score = 31.6 bits (70), Expect = 2.8
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 166 EKKTVEDADMELTSR-DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLK 224
E KT +D E+TS+ +EG++K +EL + +++ C+G L K QQ K
Sbjct: 126 EVKTSQDKFDEITSKWEEGKQKRIPQELWEMLNTQQLHCAGLLEDKNKLISELQQELKTK 185
Query: 225 NDE 227
+D+
Sbjct: 186 DDQ 188
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 31.2 bits (69), Expect = 3.7
Identities = 108/511 (21%), Positives = 190/511 (37%), Gaps = 73/511 (14%)
Query: 167 KKTVEDADMELTSRDEGERKMEKE------------ELDVSVREEEVSCSGPLSQKQAEF 214
+K VED +L ++D+ +R +E+E + + E+ S + L +K+
Sbjct: 1009 QKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRL 1068
Query: 215 FLSQQASLLKNDETKAL-----TPASLQKELN---NLLKFNPDFAEAHYLSYLNNLRVQD 266
+ Q+A ++ E AL QKEL+ LL+ EA +L+ ++ +
Sbjct: 1069 LVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLA--QEAQLLE 1126
Query: 267 VFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQE 326
++H + R L E+K+ + RS + L A + G+ QA+ L
Sbjct: 1127 ELEASH-ITEQQLRASLWAQEAKAAQLQLRLRSTE-SQLEALAAEQQPGNQAQAQAQLAS 1184
Query: 327 AIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL-LEHSVKKAVHFGLPYLASLGIQSLV 385
Q++ VC L G + L + + +++ P L +L +++
Sbjct: 1185 LYSALQQALGSVC--ESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVA 1242
Query: 386 QQRAFAGKTANKLMDALKDSDLLHWK-HSLSELIDISIAQKTAIWRLYGRSTMALQQAQM 444
+ K L + D+L + L E + + A+K+ + LQ Q
Sbjct: 1243 ---SALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQV-------HTELQDLQR 1292
Query: 445 LLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAA--------------ASEVL 490
LS N E +QN+ ES L ELH + E+L
Sbjct: 1293 QLSQNQEEKSKWEGKQNSLES------ELMELHETMASLQSRLRRAELQRMEAQGERELL 1346
Query: 491 KHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITAL----NSIEGVYR 546
+ KE +H Q + RA L + L T +AL +E
Sbjct: 1347 QAAKENLTAQVEHLQ------AAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERE 1400
Query: 547 KAVVLQAQNQM--SEAHKLLQKLLVHCQKLKNTEMVISVLL-SVAELYWRSSSPTIALPM 603
+A LQ Q ++ ++ L + L + Q L E + L + EL + AL +
Sbjct: 1401 RAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALEL 1460
Query: 604 LLQALALSKEYRLQYLASETVLNLAFAQLIL 634
L +L L K + L E + L + +L
Sbjct: 1461 L--SLDLKKRNQEVDLQQEQIQELEKCRSVL 1489
>gi|62899047 RAD50 interactor 1 [Homo sapiens]
Length = 792
Score = 31.2 bits (69), Expect = 3.7
Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Query: 559 EAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQY 618
E + L+ L KL+ ++ +++ + E Y +SP++ LP+ + L K +R +
Sbjct: 262 EIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPASPSVILPIQVMLTPLQKRFRYHF 321
Query: 619 LASETVLNLA-----FAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMF 665
+ L+ AQ+++ I L I+PIL L R F
Sbjct: 322 RGNRQTNVLSKPEWYLAQVLMWIGNHT-EFLDEKIQPILDKVGSLVNARLEF 372
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 31.2 bits (69), Expect = 3.7
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 16/81 (19%)
Query: 163 QNGEKKTVEDADMELTSRDEGERKMEKEEL----------DVSVREEEVSCSG------P 206
+ GE++ E+ + EL +E E + E+EEL + +EE+VS +G P
Sbjct: 1761 EEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQP 1820
Query: 207 LSQKQAEFFLSQQASLLKNDE 227
SQ+ ++ QQ +++ +E
Sbjct: 1821 ESQESMQWQWQQQLNVMVKEE 1841
>gi|11034845 Regulation of nuclear pre-mRNA domain containing 1B
[Homo sapiens]
Length = 326
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 48 GEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKD 107
G A L +RR+L ++L+ Q LS+ K +EE +LA Q+R ELK
Sbjct: 242 GRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVR------KELKS 295
Query: 108 MEQFFDDLS 116
Q DLS
Sbjct: 296 HIQSLPDLS 304
>gi|7656849 acyl-Coenzyme A dehydrogenase family, member 8 [Homo
sapiens]
Length = 415
Score = 30.8 bits (68), Expect = 4.9
Identities = 15/37 (40%), Positives = 20/37 (54%)
Query: 455 NAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLK 491
NA V AVALC +A+L A CFA ++ L+
Sbjct: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQ 371
>gi|226693318 adenosine deaminase-like isoform 1 [Homo sapiens]
Length = 328
Score = 30.4 bits (67), Expect = 6.3
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 182 EGERKMEKEELDVSVREEEV--SCSGPLSQKQA-----EFFLSQQASLLKNDETKALTPA 234
EG ++ ++E LD+ VR GPL K+ EFFLS + ++L D + T
Sbjct: 127 EGIKQSKQENLDIDVRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGTVLGLDLSGDPTIP 186
Query: 235 SLQKELNNLLKFNPD 249
+ +KE LL PD
Sbjct: 187 NQKKETQILLDLLPD 201
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 30.4 bits (67), Expect = 6.3
Identities = 17/62 (27%), Positives = 31/62 (50%)
Query: 166 EKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKN 225
EK+ E+ E R E E KM ++E + +EE++ + Q+Q E Q+ + +
Sbjct: 364 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ 423
Query: 226 DE 227
+E
Sbjct: 424 EE 425
>gi|21359945 chromosome condensation protein G [Homo sapiens]
Length = 1015
Score = 30.4 bits (67), Expect = 6.3
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 247 NPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAE 287
N DFA H++ L L++ DV +L FD+L+ G E
Sbjct: 615 NQDFARKHFVLLLQVLQIDDVTIKISALKAIFDQLMTFGIE 655
>gi|68077164 Yeast Sps1/Ste20-related kinase 4 isoform 1 [Homo
sapiens]
Length = 1328
Score = 30.4 bits (67), Expect = 6.3
Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 163 QNGEKKTVEDAD-MELTSRDEGERKMEKEELDV----SVREEEVSCSGPLSQKQAEFFLS 217
+N + K +E+ + +E+T ++G+ + E L +VREE++ C G ++K E S
Sbjct: 306 ENWKSKEIEECNKIEITHFEKGQSLVSFENLKEGNIPAVREEDIDCHGSKTRKPEE-ENS 364
Query: 218 QQASLLKNDETKA 230
Q S KN+ + A
Sbjct: 365 QYLSSRKNESSVA 377
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 30.0 bits (66), Expect = 8.3
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 10/73 (13%)
Query: 165 GEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLK 224
G ++ +E EL + E ER+ E+ +L + ++EE +Q E L QQ L+
Sbjct: 330 GSEQELEQQRQELERQQELERQQEQRQLQLKLQEE---------LQQLEQQLEQQQQQLE 380
Query: 225 NDETK-ALTPASL 236
E + LTP L
Sbjct: 381 QQEVQLELTPVEL 393
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,991,388
Number of Sequences: 37866
Number of extensions: 998976
Number of successful extensions: 3625
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3586
Number of HSP's gapped (non-prelim): 55
length of query: 755
length of database: 18,247,518
effective HSP length: 110
effective length of query: 645
effective length of database: 14,082,258
effective search space: 9083056410
effective search space used: 9083056410
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.