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Search of human proteins with 20127499
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20127499 arginine/serine-rich splicing factor 6 [Homo
sapiens]
(344 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 677 0.0
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 424 e-119
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 307 1e-83
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 307 1e-83
gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1 [Ho... 170 2e-42
gi|118582269 splicing factor, arginine/serine-rich 1 isoform 2 [... 131 8e-31
gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens] 130 2e-30
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 104 1e-22
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 103 2e-22
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 102 4e-22
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 100 2e-21
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 100 2e-21
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 99 7e-21
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 98 1e-20
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 94 2e-19
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 92 9e-19
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 91 2e-18
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 90 3e-18
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 89 7e-18
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 89 7e-18
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 88 1e-17
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 88 1e-17
gi|148612890 serine-arginine repressor protein [Homo sapiens] 87 2e-17
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 86 4e-17
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 85 1e-16
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 85 1e-16
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 84 1e-16
gi|52426743 cisplatin resistance-associated overexpressed protei... 83 3e-16
gi|19923485 cisplatin resistance-associated overexpressed protei... 83 3e-16
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 82 5e-16
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 677 bits (1747), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL 60
MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL
Sbjct: 1 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL 60
Query: 61 CGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSR 120
CGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSR
Sbjct: 61 CGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSR 120
Query: 121 CSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIE 180
CSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIE
Sbjct: 121 CSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIE 180
Query: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG 240
DKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG
Sbjct: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG 240
Query: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR 300
RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR
Sbjct: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR 300
Query: 301 SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD
Sbjct: 301 SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 424 bits (1091), Expect = e-119
Identities = 239/361 (66%), Positives = 270/361 (74%), Gaps = 26/361 (7%)
Query: 1 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL 60
MPRVYIGRLSY RE+D++RFF GYG++LEVDLKNGYGFVEF+D RDADDAVYELNGK+L
Sbjct: 1 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 60
Query: 61 CGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSR 120
CGERVIVEHARGPRRD SYGS G GY R SGRDKYGPP RTEYRLIVENLSSR
Sbjct: 61 CGERVIVEHARGPRRDG---SYGSGRSGYGY---RRSGRDKYGPPTRTEYRLIVENLSSR 114
Query: 121 CSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIE 180
CSWQDLKD+MRQAGEVTYADAHK R NEGVIEF SYSDMKRAL+KLDGTE+NGR IRL+E
Sbjct: 115 CSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE 174
Query: 181 DKPRTSHRRSYSGSRSRSRSRRRSR-SRSRRS---------SRSRSRSISKSRSRSRSRS 230
DKP + RRSYS SRS SRSR RSR SR RS S+SRSRS S SRSRS+SRS
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 231 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEK------SRSRSRSRSPKEN 284
+ +SRSRSK KSRS SK K +S S SRS+SKD+ E+ + + +SRSP +
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 285 GKGDIKSKSRSRSQSRS-NSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
KSKSRSRSQ R S+ RS +++ SRSRS+ S+SRSRSRS S+
Sbjct: 295 KS---KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
Query: 344 D 344
D
Sbjct: 352 D 352
Score = 127 bits (319), Expect = 1e-29
Identities = 123/391 (31%), Positives = 177/391 (45%), Gaps = 52/391 (13%)
Query: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGY---GFVEFEDSRDADDAVYELNGKE 59
R+ + LS +D++ + G + D G G +EF D A+ +L+G E
Sbjct: 105 RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTE 164
Query: 60 LCGERV-IVE----------------HARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKY 102
+ G ++ +VE H+R R R SRSG S ++ R +
Sbjct: 165 VNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRS 224
Query: 103 GPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERT------------NEGV 150
G R++ R ++ SR + + ++ A K R+ N+ V
Sbjct: 225 GSRSRSKSRSRSQS-RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 151 IEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRR 210
+ +S S + + R + E + S RS S +SRSR RS+ SR
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEE-EKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 211 SSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSR--------------SKSKSKPKSDRG 256
SRSRS+S K + R RSR + RSRSRS+ + R SK K K +DR
Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 257 -SHSHSRSRSKD-EYEKSRSRSR-SRSPKENGKGDIKSKSRSRSQSRSNSPLPVPP-SKA 312
S S SRS SK+ E+ KS S R R EN + +++SRSRS S+S LP S++
Sbjct: 403 QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
Query: 313 RSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
+S S R+ SRSRS SRS SRSRSRS SR
Sbjct: 463 KSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/164 (32%), Positives = 77/164 (46%), Gaps = 12/164 (7%)
Query: 84 SRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEV--TYADA 141
SRS GG S R+ + K R R E SR + + R+ G + A +
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSR---EESRSRSRSRSKSERSRKRGSKRDSKAGS 390
Query: 142 HKERTNEGVIEFRSYSDMK-----RALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRS 196
K++ E +S S + R K + ++ GR + + RS S S+S
Sbjct: 391 SKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKS 450
Query: 197 RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRS--RSKGRSRSRS 238
+ SRSRS+ +S++RSRS S+SRS SRS RS+ RS SRS
Sbjct: 451 KPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 307 bits (786), Expect = 1e-83
Identities = 170/279 (60%), Positives = 200/279 (71%), Gaps = 17/279 (6%)
Query: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELCG 62
RV+IGRL+ REKD++RFF GYGR+ ++DLK G+GFVEFED RDADDAVYEL+GKELC
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 63 ERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCS 122
ERV +EHAR R R G G S +SSRR + PPVRTE RLIVENLSSR S
Sbjct: 65 ERVTIEHARA--RSRGGRGRGRYSDR--FSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
Query: 123 WQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDK 182
WQDLKDFMRQAGEVT+ADAH+ + NEGV+EF SY D+K A++KL G EINGR I+LIE
Sbjct: 121 WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-- 178
Query: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSR-SRSRSRSKGRSRSRSKGR 241
GS+ SRSR RSRSR+R SSRSRSRS S+SR S SRSRS+ RSRSRSK R
Sbjct: 179 ----------GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSR 228
Query: 242 KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280
+ RGS S S+S + + ++SRSRSRSRS
Sbjct: 229 SVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
Score = 65.5 bits (158), Expect = 7e-11
Identities = 71/251 (28%), Positives = 111/251 (44%), Gaps = 41/251 (16%)
Query: 111 RLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTE 170
R+ + L+ +D++ F + G + D + G +EF D A+ +LDG E
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKR---GFGFVEFEDPRDADDAVYELDGKE 61
Query: 171 INGRNIRLIEDKPRTSHRRSYSGSRSRSRSRR-RSRSRSRRSSRSRSRSISKSRSRSRSR 229
+ + + + R+ R R SRR R+ R+ R+ +R I ++ S S
Sbjct: 62 LCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
Query: 230 SKGRSRSRSKGRKSRSKSKSKPKSDRG-----------------SHSHSRSRSKDEYEKS 272
+ R G + + + +PK + G S R E S
Sbjct: 122 QDLKDFMRQAGEVTFADAH-RPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS 180
Query: 273 RSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRS 332
+ SRSRS +S+SR+RS SRS S S++RS +++ SRSRSRSRS
Sbjct: 181 KRHSRSRS---------RSRSRTRSSSRSRS-----RSRSRS-----RKSYSRSRSRSRS 221
Query: 333 KSRSRSRSSSR 343
+SRS+SRS SR
Sbjct: 222 RSRSKSRSVSR 232
>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 307 bits (786), Expect = 1e-83
Identities = 170/279 (60%), Positives = 200/279 (71%), Gaps = 17/279 (6%)
Query: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELCG 62
RV+IGRL+ REKD++RFF GYGR+ ++DLK G+GFVEFED RDADDAVYEL+GKELC
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 63 ERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCS 122
ERV +EHAR R R G G S +SSRR + PPVRTE RLIVENLSSR S
Sbjct: 65 ERVTIEHARA--RSRGGRGRGRYSDR--FSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
Query: 123 WQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDK 182
WQDLKDFMRQAGEVT+ADAH+ + NEGV+EF SY D+K A++KL G EINGR I+LIE
Sbjct: 121 WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-- 178
Query: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSR-SRSRSRSKGRSRSRSKGR 241
GS+ SRSR RSRSR+R SSRSRSRS S+SR S SRSRS+ RSRSRSK R
Sbjct: 179 ----------GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSR 228
Query: 242 KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280
+ RGS S S+S + + ++SRSRSRSRS
Sbjct: 229 SVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
Score = 65.5 bits (158), Expect = 7e-11
Identities = 71/251 (28%), Positives = 111/251 (44%), Gaps = 41/251 (16%)
Query: 111 RLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTE 170
R+ + L+ +D++ F + G + D + G +EF D A+ +LDG E
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKR---GFGFVEFEDPRDADDAVYELDGKE 61
Query: 171 INGRNIRLIEDKPRTSHRRSYSGSRSRSRSRR-RSRSRSRRSSRSRSRSISKSRSRSRSR 229
+ + + + R+ R R SRR R+ R+ R+ +R I ++ S S
Sbjct: 62 LCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
Query: 230 SKGRSRSRSKGRKSRSKSKSKPKSDRG-----------------SHSHSRSRSKDEYEKS 272
+ R G + + + +PK + G S R E S
Sbjct: 122 QDLKDFMRQAGEVTFADAH-RPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS 180
Query: 273 RSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRS 332
+ SRSRS +S+SR+RS SRS S S++RS +++ SRSRSRSRS
Sbjct: 181 KRHSRSRS---------RSRSRTRSSSRSRS-----RSRSRS-----RKSYSRSRSRSRS 221
Query: 333 KSRSRSRSSSR 343
+SRS+SRS SR
Sbjct: 222 RSRSKSRSVSR 232
>gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1 [Homo
sapiens]
Length = 248
Score = 170 bits (430), Expect = 2e-42
Identities = 111/243 (45%), Positives = 141/243 (58%), Gaps = 18/243 (7%)
Query: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYG-----FVEFEDSRDADDAVYELNG 57
R+Y+G L ++R KDI+ F YG + ++DLKN G FVEFED RDA+DAVY +G
Sbjct: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDG 76
Query: 58 KELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVR-TEYRLIVEN 116
+ G R+ VE R R G G GGGG + R +YGPP R +E R++V
Sbjct: 77 YDYDGYRLRVEFPRSGR----GTGRGGGGGGGGGAPR-----GRYGPPSRRSENRVVVSG 127
Query: 117 LSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNI 176
L SWQDLKD MR+AG+V YAD +++ T GV+EF DM A+ KLD T+
Sbjct: 128 LPPSGSWQDLKDHMREAGDVCYADVYRDGT--GVVEFVRKEDMTYAVRKLDNTKFRSHEG 185
Query: 177 RLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSR-SRSKGRSR 235
+ + RS S RSRSRSR RSRSRSR +SRSRS S +SR R S RSR
Sbjct: 186 ETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSR 245
Query: 236 SRS 238
SR+
Sbjct: 246 SRT 248
Score = 48.1 bits (113), Expect = 1e-05
Identities = 67/261 (25%), Positives = 97/261 (37%), Gaps = 48/261 (18%)
Query: 103 GPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNE--GVIEFRSYSDMK 160
GP + R+ V NL +D++D + G + D R +EF D +
Sbjct: 9 GPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAE 68
Query: 161 RALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSIS 220
A+ DG + +G +R+ + PR+ G R R S RS +R +
Sbjct: 69 DAVYGRDGYDYDGYRLRV--EFPRSGRGTGRGGGGGGGGGAPRGRY-GPPSRRSENRVVV 125
Query: 221 KSRSRSRSRSKGRSRSRSKG------------------RKS------RSKSKSKPKSDRG 256
S S + R G RK R +K +S G
Sbjct: 126 SGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEG 185
Query: 257 SHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVS 316
++ R + S RSRSRS +S+SRSRS+S S S RS S
Sbjct: 186 ETAYIRVKVDGPRSPSYGRSRSRS---------RSRSRSRSRSNSRS---------RSYS 227
Query: 317 PPPKRATSR-SRSRSRSKSRS 336
P R + R S SRS+SR+
Sbjct: 228 PRRSRGSPRYSPRHSRSRSRT 248
>gi|118582269 splicing factor, arginine/serine-rich 1 isoform 2
[Homo sapiens]
Length = 201
Score = 131 bits (330), Expect = 8e-31
Identities = 79/180 (43%), Positives = 105/180 (58%), Gaps = 17/180 (9%)
Query: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYG-----FVEFEDSRDADDAVYELNG 57
R+Y+G L ++R KDI+ F YG + ++DLKN G FVEFED RDA+DAVY +G
Sbjct: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDG 76
Query: 58 KELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVR-TEYRLIVEN 116
+ G R+ VE R R G G GGGG + R +YGPP R +E R++V
Sbjct: 77 YDYDGYRLRVEFPRSGR----GTGRGGGGGGGGGAPR-----GRYGPPSRRSENRVVVSG 127
Query: 117 LSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNI 176
L SWQDLKD MR+AG+V YAD +++ T GV+EF DM A+ KLD T+ +
Sbjct: 128 LPPSGSWQDLKDHMREAGDVCYADVYRDGT--GVVEFVRKEDMTYAVRKLDNTKFRSHEV 185
>gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens]
Length = 221
Score = 130 bits (327), Expect = 2e-30
Identities = 86/216 (39%), Positives = 115/216 (53%), Gaps = 25/216 (11%)
Query: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYG-----FVEFEDSRDADDAVYELNG 57
R+Y+G L +VREKD++ F YGR+ E++LKN +G FV FED RDA+DA+Y NG
Sbjct: 15 RIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNG 74
Query: 58 KELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVR-TEYRLIVEN 116
+ R+ VE R +YG R G GR+ GPP R +++R++V
Sbjct: 75 YDYGQCRLRVEFPR---------TYGGRGGWP------RGGRN--GPPTRRSDFRVLVSG 117
Query: 117 LSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNI 176
L SWQDLKD MR+AG+V YAD K+ G++E+ DM+ AL KLD T+
Sbjct: 118 LPPSGSWQDLKDHMREAGDVCYADVQKD--GVGMVEYLRKEDMEYALRKLDDTKFRSHEG 175
Query: 177 RLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSS 212
+ SY SRSRS SR R R S
Sbjct: 176 ETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGS 211
>gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
Length = 262
Score = 104 bits (260), Expect = 1e-22
Identities = 81/291 (27%), Positives = 142/291 (48%), Gaps = 50/291 (17%)
Query: 4 VYIGRLSYNVREKDIQRFFSGYGRLLEVDLK--------NGYGFVEFEDSRDADDAVYEL 55
+++ ++ + R +D++R F YG +++V + G+ +V+FED RDA+DA++ L
Sbjct: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
Query: 56 NGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVE 115
+ K +CG ++ ++ A+G R+ + ++ G YSS R D+Y
Sbjct: 72 DRKWICGRQIEIQFAQGDRKTPN--QMKAKEGRNVYSSSRYDDYDRY------------- 116
Query: 116 NLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRN 175
SR + + ++ + Y ++ R + R +R+ D RN
Sbjct: 117 -RRSRSRSYERRRSRSRSFDYNYRRSYSPRNS------RPTGRPRRSRSHSDNDRFKHRN 169
Query: 176 IRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
RS+S S+S SRSR +S+ + ++SRSRS S +++R S++ ++
Sbjct: 170 -------------RSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTH 216
Query: 236 SRSKGR-KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENG 285
+S R + S+ K P+S S S SRSRS KSRSRS + SPK +G
Sbjct: 217 YKSGSRYEKESRKKEPPRSKSQSRSQSRSRS-----KSRSRSWT-SPKSSG 261
Score = 86.3 bits (212), Expect = 4e-17
Identities = 82/214 (38%), Positives = 108/214 (50%), Gaps = 32/214 (14%)
Query: 151 IEFRSYSDMKRALDKLDGTEINGRNIRL--IEDKPRTSH-------RRSYSGSRSRSRSR 201
++F D + AL LD I GR I + + +T + R YS SR R
Sbjct: 56 VQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDR 115
Query: 202 -RRSRSRSRRSSRSRSRSISKSRSRS----RSRSKGRSR-SRSKGRKSRSKSKSKPKSDR 255
RRSRSRS RSRSRS + RS SR GR R SRS R K +++ S
Sbjct: 116 YRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRS 175
Query: 256 GSHSHSRSRSKDEYE-KSRSRSRSRS-------PKENGKGDIKSKSRSRSQSRSNSPLPV 307
S+S SRS+S+ + E K++SRSRS S K + K KS SR +SR P
Sbjct: 176 KSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEP--- 232
Query: 308 PPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
P SK++S R+ SRSRS+SRS+S + +SS
Sbjct: 233 PRSKSQS------RSQSRSRSKSRSRSWTSPKSS 260
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 103 bits (257), Expect = 2e-22
Identities = 95/272 (34%), Positives = 120/272 (44%), Gaps = 61/272 (22%)
Query: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKN---GYGFVEFEDSRDADDAVYELNGKE 59
+VY+G L + +++R FS YG L V + G+ FVEFED RDA+DAV L+GK
Sbjct: 12 KVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKV 71
Query: 60 LCGERVIVEHARG-PRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLS 118
+CG RV VE + G PRR R PP R +
Sbjct: 72 ICGSRVRVELSTGMPRRSRFD-----------------------RPPARRPF-------- 100
Query: 119 SRCSWQDLKDFMRQAGEVTY--ADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNI 176
D D + GE + D H+ YS +R+ + + R
Sbjct: 101 ------DPNDRCYECGEKGHYAYDCHR------------YSRRRRSRSR-SRSHSRSRGR 141
Query: 177 RLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSR-----SRSRSRSK 231
R + R+ RRS S S RSRS RSRS RSRS SI SR SRSRSRS+
Sbjct: 142 RYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSR 201
Query: 232 GRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRS 263
SR RS KSRS S + +S GS S S
Sbjct: 202 SISRPRSSRSKSRSPSPKRSRSPSGSPRRSAS 233
Score = 82.0 bits (201), Expect = 7e-16
Identities = 85/242 (35%), Positives = 105/242 (43%), Gaps = 30/242 (12%)
Query: 109 EYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDG 168
E ++ V NL + +L+ G + + +EF D + A+ LDG
Sbjct: 10 ETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDG 69
Query: 169 TEINGRNIR--LIEDKPRTS-------------HRRSYSGSRSRSRSRRRSRSRSRRSSR 213
I G +R L PR S + R Y + R RR SR
Sbjct: 70 KVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSR 129
Query: 214 SRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSR 273
SRSR S SRSR R RSRSRS+GR+SRS S R S S S RS +S
Sbjct: 130 SRSR----SHSRSRGRRYSRSRSRSRGRRSRS------ASPRRSRSISLRRS-----RSA 174
Query: 274 SRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK 333
S RSRS G +S SRSRS+SRS S SK+RS SP R+ S S RS S
Sbjct: 175 SLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASP 234
Query: 334 SR 335
R
Sbjct: 235 ER 236
Score = 45.1 bits (105), Expect = 9e-05
Identities = 36/83 (43%), Positives = 44/83 (53%), Gaps = 19/83 (22%)
Query: 258 HSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSP 317
H +SR R +SRSRSRS S +G S+SRSRS+ R ++RS SP
Sbjct: 120 HRYSRRR------RSRSRSRSHS---RSRGRRYSRSRSRSRGR----------RSRSASP 160
Query: 318 PPKRATSRSRSRSRSKSRSRSRS 340
R+ S RSRS S RSRS S
Sbjct: 161 RRSRSISLRRSRSASLRRSRSGS 183
Score = 30.4 bits (67), Expect = 2.4
Identities = 15/24 (62%), Positives = 18/24 (75%)
Query: 320 KRATSRSRSRSRSKSRSRSRSSSR 343
+R+ SRSRS SRS+ R SRS SR
Sbjct: 126 RRSRSRSRSHSRSRGRRYSRSRSR 149
Score = 30.0 bits (66), Expect = 3.2
Identities = 18/28 (64%), Positives = 20/28 (71%), Gaps = 4/28 (14%)
Query: 320 KRATSRSRSRSRSKSR----SRSRSSSR 343
+R SRSRSRS S+SR SRSRS SR
Sbjct: 124 RRRRSRSRSRSHSRSRGRRYSRSRSRSR 151
Score = 29.3 bits (64), Expect = 5.4
Identities = 15/23 (65%), Positives = 16/23 (69%)
Query: 321 RATSRSRSRSRSKSRSRSRSSSR 343
R+ S SRSR R SRSRSRS R
Sbjct: 131 RSRSHSRSRGRRYSRSRSRSRGR 153
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 102 bits (255), Expect = 4e-22
Identities = 89/213 (41%), Positives = 112/213 (52%), Gaps = 34/213 (15%)
Query: 104 PPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAH-------KERTNEGVIEFRSY 156
P V L V+NL+ R S L+ + G V D + KE + F
Sbjct: 8 PDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRV--GDVYIPRDRYTKESRGFAFVRFHDK 65
Query: 157 SDMKRALDKLDGTEINGRNIRLIE---DKPRTSHR-------RSYSGS----RSRS-RSR 201
D + A+D +DG ++GR +R+ +P SH R Y G RSRS R R
Sbjct: 66 RDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRR 125
Query: 202 RRSRSRSRRSSRSRSRSI---SKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSH 258
RRSRSRSR SRSRSRS SKSRSR+RSRS+ S+SRS R+S+SKS S +S S
Sbjct: 126 RRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRS-ARRSKSKSSSVSRSRSRSR 184
Query: 259 SHSRSRS----KDEYEKSRSRSRS--RSPKENG 285
S SRSRS KSRSRS+S +SP+E G
Sbjct: 185 SRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEG 217
Score = 71.6 bits (174), Expect = 9e-13
Identities = 76/251 (30%), Positives = 101/251 (40%), Gaps = 66/251 (26%)
Query: 1 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDL--------KNGYGFVEFEDSRDADDAV 52
M + + L+Y ++R F YGR+ +V + G+ FV F D RDA+DA+
Sbjct: 13 MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAM 72
Query: 53 YELNGKELCGERVIVEHARGPRRDRDGYSYGS----RSGGGGYSSRRTSGRDKYGPPVRT 108
++G L G + V+ AR R +S R GGGGY R S R + R+
Sbjct: 73 DAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRS 132
Query: 109 EYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDG 168
R SR + K + RT RS S K
Sbjct: 133 RSR---SRSRSRSRYSRSKS--------------RSRTRS-----RSRSTSK-------- 162
Query: 169 TEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRS---ISKSRSR 225
S S RS+S+S SRSRSR SRSRSRS +SK S+
Sbjct: 163 ---------------------SRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESK 201
Query: 226 SRSRSKGRSRS 236
SRSRSK +S
Sbjct: 202 SRSRSKSPPKS 212
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/87 (42%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 257 SHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVS 316
SH R Y RSRSP+ + +S+SRSRS+SRS SK+RS +
Sbjct: 98 SHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSR----YSRSKSRSRT 153
Query: 317 PPPKRATSRSRSRSRSKSRSRSRSSSR 343
R+TS+SRS RSKS+S S S SR
Sbjct: 154 RSRSRSTSKSRSARRSKSKSSSVSRSR 180
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 100 bits (249), Expect = 2e-21
Identities = 73/164 (44%), Positives = 96/164 (58%), Gaps = 21/164 (12%)
Query: 180 EDKPRTSHRRSYSG---SRSRSRSRR-RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
ED+ + R+S G SRSRSR RR RSRSR R+ SRSRSR KSRSRSR R K RSR
Sbjct: 50 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295
SR + R+ RS+S+S R H H R+RS +SR+RSRSR K+ + K + S
Sbjct: 110 SRERKRRIRSRSRS-----RSRHRH-RTRS-----RSRTRSRSRDRKKRIE---KPRRFS 155
Query: 296 RSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSR 339
RS SR+ SP PP + R+ + + A +R R++ R +
Sbjct: 156 RSLSRTPSP---PPFRGRNTAMDAQEALARRLERAKKLQEQREK 196
Score = 85.9 bits (211), Expect = 5e-17
Identities = 71/199 (35%), Positives = 101/199 (50%), Gaps = 17/199 (8%)
Query: 145 RTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRS 204
RTN + + R + ++ K E N + DK R S +G R R+S
Sbjct: 3 RTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHS--SDKGRERLNSSENGEDRHKRKERKS 60
Query: 205 RSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSR 264
SR R SRSRSR + RSRSR R K RSRSR + +KSRS+S+ + KS RSR
Sbjct: 61 -SRGRSHSRSRSRE-RRHRSRSRERKKSRSRSRER-KKSRSRSRERKKS--------RSR 109
Query: 265 SKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRS---NSPLPVPPSKARSVSPPPKR 321
S++ + RSRSRSRS + + +S++RSRS+ R P S +R+ SPPP R
Sbjct: 110 SRERKRRIRSRSRSRS-RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFR 168
Query: 322 ATSRSRSRSRSKSRSRSRS 340
+ + + +R R+
Sbjct: 169 GRNTAMDAQEALARRLERA 187
Score = 80.1 bits (196), Expect = 3e-15
Identities = 62/165 (37%), Positives = 80/165 (48%), Gaps = 36/165 (21%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
E K ++S + + S + R R S R K R SR RS RSRSR +
Sbjct: 15 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 74
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299
+SRS+ + K SRSRS+ E +KSRSRSR R KS+SRSR +
Sbjct: 75 RHRSRSRERKK----------SRSRSR-ERKKSRSRSRERK---------KSRSRSRERK 114
Query: 300 RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
R + RS R+ SRSR R R++SRSR+RS SRD
Sbjct: 115 R----------RIRS------RSRSRSRHRHRTRSRSRTRSRSRD 143
Score = 57.4 bits (137), Expect = 2e-08
Identities = 40/105 (38%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQ 298
+GR+ SK KS K H+ S +K R R S ENG+ K K R S+
Sbjct: 10 QGRRHESKDKSSKKHKSEEHNDKEHSS----DKGRERLNS---SENGEDRHKRKERKSSR 62
Query: 299 SRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
RS+S + RS S K++ SRSR R +S+SRSR R SR
Sbjct: 63 GRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR 107
Score = 34.3 bits (77), Expect = 0.17
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 177 RLIEDKPRT-SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
R I + R+ S R + SRSR+RSR R R + R SRS+S++ S R + +
Sbjct: 115 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 174
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD 267
+ R + K + R + + ++
Sbjct: 175 DAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 100 bits (249), Expect = 2e-21
Identities = 73/164 (44%), Positives = 96/164 (58%), Gaps = 21/164 (12%)
Query: 180 EDKPRTSHRRSYSG---SRSRSRSRR-RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
ED+ + R+S G SRSRSR RR RSRSR R+ SRSRSR KSRSRSR R K RSR
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295
SR + R+ RS+S+S R H H R+RS +SR+RSRSR K+ + K + S
Sbjct: 169 SRERKRRIRSRSRS-----RSRHRH-RTRS-----RSRTRSRSRDRKKRIE---KPRRFS 214
Query: 296 RSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSR 339
RS SR+ SP PP + R+ + + A +R R++ R +
Sbjct: 215 RSLSRTPSP---PPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
Score = 92.4 bits (228), Expect = 5e-19
Identities = 67/178 (37%), Positives = 87/178 (48%), Gaps = 22/178 (12%)
Query: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
PR S + YS SRSRSR R+R R RSRSRS R S+ +S + +S K
Sbjct: 33 PRAS-KHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDK 91
Query: 243 SRSKSKSKP-----------------KSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENG 285
S K + KS RG SHSRSRS++ +SRSR R +S +
Sbjct: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRG-RSHSRSRSRERRHRSRSRERKKSRSRSR 150
Query: 286 KGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
+ + KSRSRS+ R S K R S R+ R R+RSRS++RSRSR +
Sbjct: 151 E---RKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205
Score = 87.4 bits (215), Expect = 2e-17
Identities = 61/165 (36%), Positives = 87/165 (52%), Gaps = 11/165 (6%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
E K ++ + SRSRS+ RR S+ + S + +S + + S KGR R S
Sbjct: 49 ERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKS---EEHNDKEHSSDKGRERLNSS 105
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299
+ + KS RG SHSRSRS++ +SRSR R +S + + KS+SRSR +
Sbjct: 106 ENGEDRHKRKERKSSRG-RSHSRSRSRERRHRSRSRERKKS-RSRSRERKKSRSRSRERK 163
Query: 300 RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
+S S + RS R+ SRSR R R++SRSR+RS SRD
Sbjct: 164 KSRSRSRERKRRIRS------RSRSRSRHRHRTRSRSRTRSRSRD 202
Score = 82.8 bits (203), Expect = 4e-16
Identities = 57/165 (34%), Positives = 80/165 (48%), Gaps = 4/165 (2%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
E K ++S + + S + R R S R K R SR RS RSRSR +
Sbjct: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299
+SRS+ + K +S SRSRS+ E +KSRSRSR R + + +S+ R R++S
Sbjct: 134 RHRSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192
Query: 300 RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
RS + K R P R SRS SR+ S R R+++ D
Sbjct: 193 RSRTRSRSRDRKKRIEKP---RRFSRSLSRTPSPPPFRGRNTAMD 234
Score = 82.0 bits (201), Expect = 7e-16
Identities = 57/154 (37%), Positives = 80/154 (51%), Gaps = 10/154 (6%)
Query: 196 SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKP---- 251
S R +++ +S S R+ S+SRSRSR R + +S ++GRK RS+S+SK
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKR---KSDNEGRKHRSRSRSKEGRRH 73
Query: 252 -KSDRGSHSHSRSRSKD-EYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPP 309
D+ S H D E+ + R R S ENG+ K K R S+ RS+S
Sbjct: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNS-SENGEDRHKRKERKSSRGRSHSRSRSRE 132
Query: 310 SKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
+ RS S K++ SRSR R +S+SRSR R SR
Sbjct: 133 RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR 166
Score = 80.1 bits (196), Expect = 3e-15
Identities = 58/173 (33%), Positives = 85/173 (49%), Gaps = 14/173 (8%)
Query: 180 EDKPRTSHR------RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR 233
+DK H+ + +S + R R R + R S +S SRSRSR + R
Sbjct: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-R 134
Query: 234 SRSRSKGR-KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSK 292
RSRS+ R KSRS+S+ + KS S +SRS+ K R RSRSRS + + +S+
Sbjct: 135 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS-RSRHRHRTRSR 193
Query: 293 SRSRSQSRS-----NSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRS 340
SR+RS+SR P S +R+ SPPP R + + + +R R+
Sbjct: 194 SRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERA 246
Score = 34.3 bits (77), Expect = 0.17
Identities = 40/134 (29%), Positives = 52/134 (38%), Gaps = 30/134 (22%)
Query: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGD---IKSKSRSRS 297
R + K+ P D+ S S + SRSRSRS + K D K +SRSRS
Sbjct: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRS 67
Query: 298 -QSRSNSPLPVPPSKARSVSPPPK-------------------------RATSRSRSRSR 331
+ R + K +S K R +SR RS SR
Sbjct: 68 KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 127
Query: 332 SKSRS-RSRSSSRD 344
S+SR R RS SR+
Sbjct: 128 SRSRERRHRSRSRE 141
Score = 34.3 bits (77), Expect = 0.17
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 177 RLIEDKPRT-SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
R I + R+ S R + SRSR+RSR R R + R SRS+S++ S R + +
Sbjct: 174 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 233
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD 267
+ R + K + R + + ++
Sbjct: 234 DAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 98.6 bits (244), Expect = 7e-21
Identities = 77/197 (39%), Positives = 107/197 (54%), Gaps = 16/197 (8%)
Query: 154 RSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSR---RRSRSRSRR 210
RS S + + T+ GR+ + SH RS +R RSRSR RR RSRSR
Sbjct: 533 RSRSPQRPGWSRSRNTQRRGRSRSARRGR---SHSRS-PATRGRSRSRTPARRGRSRSRT 588
Query: 211 SSRSRSRSISKSRSRSRSRS---KGRSRSRSKGRK-SRSKSKSKPKSDRGSHSHSRSRSK 266
+R RSRS + +R RSRSR+ +GRSRSR+ R+ SR++S + +S S + RS+
Sbjct: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSR 648
Query: 267 DEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRS 326
R RSRSR+P G+ ++ +R +SRS +P + RS S P+R SRS
Sbjct: 649 SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA----RRGRSRSRTPRRGRSRS 704
Query: 327 RSRSRSKSRSRSRSSSR 343
RS R + RS SR+ R
Sbjct: 705 RSLVR-RGRSHSRTPQR 720
Score = 92.4 bits (228), Expect = 5e-19
Identities = 70/187 (37%), Positives = 102/187 (54%), Gaps = 28/187 (14%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSR----------------SRRSSRSRSRSISKSR 223
++ RTS RR SR+ SR+RSRSR + R SRSR+ IS+ R
Sbjct: 1828 QESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRR 1887
Query: 224 SRSRSR--SKGRSRSRSKGRKSRSKSKSKPKSDRGSHSH----SRSRSKDEYEKSRSRSR 277
SRSR+ S+ RSRSR+ + RS+S++ P S R S S +R RS+ +R RSR
Sbjct: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947
Query: 278 SRSP---KENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKS 334
SR+P + + +R RS+SR++ P+ ++RS + P R SRSR+ ++
Sbjct: 1948 SRTPPVTRRRSRSRTPPVTRRRSRSRTS---PITRRRSRSRTSPVTRRRSRSRTSPVTRR 2004
Query: 335 RSRSRSS 341
RSRSR+S
Sbjct: 2005 RSRSRTS 2011
Score = 90.1 bits (222), Expect = 3e-18
Identities = 74/187 (39%), Positives = 97/187 (51%), Gaps = 25/187 (13%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRS---RRSSRSRSRSISK---SRSRS----RSRSK 231
K R+ R S S + SRR RSRS + RSRSR+ +K SRSRS RSRS
Sbjct: 460 KNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSA 519
Query: 232 GR-SRSRSKGRKSRSKSKSKPKSDRG--------SHSHSRSRSKDEYEKSRSRSRSRSPK 282
R RSRS R+ RS+S +P R S S R RS +R RSRSR+P
Sbjct: 520 QRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPA 579
Query: 283 ENGKGDIKSKSRSRSQS------RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRS 336
G+ ++ +R RS+S RS S P ++RS +P +R+ +RS R RS+SRS
Sbjct: 580 RRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRS 639
Query: 337 RSRSSSR 343
+R S R
Sbjct: 640 PARRSGR 646
Score = 89.7 bits (221), Expect = 3e-18
Identities = 69/161 (42%), Positives = 97/161 (60%), Gaps = 14/161 (8%)
Query: 188 RRSYSGSR-SRSRS-RRRSRSRS-RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSR 244
RRS S R RSRS +RR RSRS +R SRSR+ + R RSRS +GRS SRS + R
Sbjct: 514 RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR-RGRSRSARRGRSHSRSPATRGR 572
Query: 245 SKSKSKPKSDRG-SHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNS 303
S+S++ + R S + +R RS+ +R RSRSR+P G+ ++ +R RS++RS
Sbjct: 573 SRSRTPARRGRSRSRTPARRRSRSR-TPTRRRSRSRTPARRGRSRSRTPARRRSRTRS-- 629
Query: 304 PLPVPPSKARSVSPPPKRATSRSRSRSRS-KSRSRSRSSSR 343
P + RS S P R + RSRSR+ + + RSRSR+ +R
Sbjct: 630 -----PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
Score = 89.7 bits (221), Expect = 3e-18
Identities = 72/171 (42%), Positives = 100/171 (58%), Gaps = 25/171 (14%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRS-RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG 240
+ RT RR SRSR+ +RRRSRSR+ R RSRSR+ ++ RSR+RS + RSRSRS
Sbjct: 585 RSRTPARRR---SRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPA 641
Query: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRS--------RSRSRSPKENGKGDIKSK 292
R+S +S+S+ + RG SRSR+ +SRS RSRSR+P G+ ++
Sbjct: 642 RRS-GRSRSRTPARRG---RSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTP 697
Query: 293 SRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
R RS+SRS + RS S P+R R RS S S+ +++SR+S R
Sbjct: 698 RRGRSRSRS------LVRRGRSHSRTPQR---RGRSGSSSERKNKSRTSQR 739
Score = 89.4 bits (220), Expect = 4e-18
Identities = 69/169 (40%), Positives = 99/169 (58%), Gaps = 19/169 (11%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRS--RRSSRSRSRSISKSRSRSRSRS---KGRSRS 236
+ RT RR SR+RS RRRSRSRS RRS RSRSR+ ++ R RSRSR+ +GRSRS
Sbjct: 616 RSRTPARRR---SRTRSPVRRRSRSRSPARRSGRSRSRTPAR-RGRSRSRTPARRGRSRS 671
Query: 237 RSKGRKS-RSKSKSKPKSDRG-SHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
R+ R+S RS+S++ + R S + R RS+ R RS SR+P+ G+ S+ +
Sbjct: 672 RTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERK 731
Query: 295 SRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
++S++ ++RS S P + + S RSRS S RS++ SR
Sbjct: 732 NKSRTSQR--------RSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Score = 87.4 bits (215), Expect = 2e-17
Identities = 92/299 (30%), Positives = 132/299 (44%), Gaps = 34/299 (11%)
Query: 70 ARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDF 129
+R R G S +R G S T GR + P R +R +
Sbjct: 543 SRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR--SRTPARRRSRSRTPT 600
Query: 130 MRQAGEVTYADAHKERTNEGVIE-FRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHR 188
R++ T A + R+ R+ S ++R +GR+ + RT R
Sbjct: 601 RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRS------RSRTPAR 654
Query: 189 RSYSGSRSRSR-SRRRSRSRSRRSSRSRSRSISKSRSRSRSRS--KGRSRSRSKGRKSRS 245
R S SR+ +R R RSR+ +RRS RSRSR+ ++ R RSRSR+ +GRSRSRS R+ RS
Sbjct: 655 RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLVRRGRS 713
Query: 246 KSKS------------KPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293
S++ + R S SRS S E +KSR SR + + KS+
Sbjct: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL 773
Query: 294 RSRSQSRSNSPLP-----VPPSKARSVSPPPKRAT----SRSRSRSRSKSRSRSRSSSR 343
R +SP P PP ++RS S PK + RSRS S + +S++ SR
Sbjct: 774 SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
Score = 87.0 bits (214), Expect = 2e-17
Identities = 73/196 (37%), Positives = 96/196 (48%), Gaps = 35/196 (17%)
Query: 181 DKPRTSHRRSYSGS---------RSRSRSRRRSRSR------SRRSSRSRSRSISKSRSR 225
+K RT+ RR SGS RSRSRSR R R SR +R S S R R
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
Query: 226 SRSRSKGRSRSRSKGRKS-----RSKSKSKPKSDRGSHSHS------RSRSK-DEYEKSR 273
RSR+ SR RS+ R S RS+S++ P + R S S + RSRS+ + R
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
Query: 274 SRSRSRSPKENGKGDIKSKSRSRSQS--------RSNSPLPVPPSKARSVSPPPKRATSR 325
SRSR+ + + SR RS+S RS S P ++RS +PP R SR
Sbjct: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR 1959
Query: 326 SRSRSRSKSRSRSRSS 341
SR+ ++ RSRSR+S
Sbjct: 1960 SRTPPVTRRRSRSRTS 1975
Score = 87.0 bits (214), Expect = 2e-17
Identities = 103/311 (33%), Positives = 143/311 (45%), Gaps = 52/311 (16%)
Query: 70 ARGPRRDRDGYSYGSRSGG----GGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQD 125
+R RR R G Y SRS SSRR GR + P R R + +S W+
Sbjct: 1808 SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSR----SRTSPAPWK- 1862
Query: 126 LKDFMRQAGEVTYADAHKERTNEGVIEFR------SYSDMKRALDKLDGTEINGRNIRLI 179
R + A + R+ +I R S +R+ + T R+ R
Sbjct: 1863 -----RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS-RAS 1916
Query: 180 EDKPRTSHRRSYSGSRSRSRSR-----RRSRSRS----RRSSRSRSRSISKSRSRSRSRS 230
R S R+ +R RSRSR RRSRSR+ RR SRSR+ +++ RSRSR+
Sbjct: 1917 PVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP 1976
Query: 231 KGRSRSRSKGR---KSRSKSKSKPKSDRGSHSHS------RSRSKDEYEKSRSRSRSRSP 281
R RSRS+ + RS+S++ P + R S S + RSRS+ R RSRSR+P
Sbjct: 1977 ITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP-PAIRRRSRSRTP 2035
Query: 282 KENGKGDIKSKSRS----RSQSRSNSPLPVPPSKARSVSPPPKRATSRS-----RSRSRS 332
K +S+SRS R +SRS +P ++ + SPP R S S RSRS +
Sbjct: 2036 LLPRK---RSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092
Query: 333 KSRSRSRSSSR 343
+R+ S SR
Sbjct: 2093 PPATRNHSGSR 2103
Score = 80.5 bits (197), Expect = 2e-15
Identities = 71/178 (39%), Positives = 93/178 (52%), Gaps = 19/178 (10%)
Query: 182 KPRTSHRRSYSGS-------RSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR- 233
+ +T+ RR S S RSRSRSRR +RR RS S S S SR R RSRS+ R
Sbjct: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS-SQSTSRRRQRSRSRSRV 1810
Query: 234 SRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSR-SPKENGKGDIKSK 292
+R R G S+S ++ +S R S R RS+ SR RSRSR SP + ++
Sbjct: 1811 TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP-PTSRKRSRSRTSPAPWKRSRSRAS 1869
Query: 293 SRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRS-------RSRSRSKSRSRSRSSSR 343
+ +SRS +PL + ++RS + P R SRS RSRSR+ SR RS SR
Sbjct: 1870 PATHRRSRSRTPL-ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSR 1926
Score = 79.7 bits (195), Expect = 3e-15
Identities = 67/167 (40%), Positives = 94/167 (56%), Gaps = 16/167 (9%)
Query: 181 DKPRTSHRR-SYSGSRSRSRSRR-RSRS---RSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
+K R+S RR S S R+++ SRR RS S R + SRSRSR +R R RS G S+
Sbjct: 1737 EKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRS-GSSQ 1795
Query: 236 SRSKGR-KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
S S+ R +SRS+S+ + GS HSRS ++ E ++ SR R G+ SR
Sbjct: 1796 STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRR------RGRSRTPPTSR 1849
Query: 295 SRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
RS+SR++ P P ++RS + P SRSR+ S+ RSRSR+S
Sbjct: 1850 KRSRSRTS---PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS 1893
Score = 77.8 bits (190), Expect = 1e-14
Identities = 56/162 (34%), Positives = 76/162 (46%), Gaps = 12/162 (7%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR 241
K RT+ R S S +++SR R RS RSS +R SR + S +RSR+ R
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 242 KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRS 301
RS S S P+ S S R RS + R RSP +G +S+SRSR +
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE--- 1780
Query: 302 NSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
K R+ + +S+S SR R +SRSRSR + R
Sbjct: 1781 ---------KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813
Score = 77.4 bits (189), Expect = 2e-14
Identities = 64/164 (39%), Positives = 86/164 (52%), Gaps = 15/164 (9%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSR---RSSRSRSRSISKSRSRSRSRSKGRSRSRS 238
+ RT RR RSRSR+ RR RSRSR R RS SR+ + R RS S S+ +++SR+
Sbjct: 682 RSRTPARRG----RSRSRTPRRGRSRSRSLVRRGRSHSRT-PQRRGRSGSSSERKNKSRT 736
Query: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS--- 295
R+SRS S + K R S SRS S K++SR R K KS++
Sbjct: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPR-SKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795
Query: 296 RSQSRSNSPLP---VPPSKARSVSPPPKRATSRSRSRSRSKSRS 336
RS+S S+ P PP ++RS S PP + S++ SR S S
Sbjct: 796 RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSS 839
Score = 72.4 bits (176), Expect = 6e-13
Identities = 60/175 (34%), Positives = 83/175 (47%), Gaps = 11/175 (6%)
Query: 179 IEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKS------RSRSRSRSKG 232
++ K R S RRS SGS + + R+ R++ S S + + RSRS S SKG
Sbjct: 1585 VDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKG 1644
Query: 233 RSRSRSKGRKSRSKSKSKPKS---DRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDI 289
R S + S + PKS RGS S ++K R SRS SP+ K +
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS-SPELTRKARL 1703
Query: 290 KSKSRSRSQS-RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
+SRS S S + S P ++ SVS P SRS R RS S R++++SR
Sbjct: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758
Score = 70.1 bits (170), Expect = 3e-12
Identities = 60/167 (35%), Positives = 78/167 (46%), Gaps = 9/167 (5%)
Query: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
PR RRS SGS S+ R S S SS +R SRS + +++SR+ R
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR- 1687
Query: 243 SRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRS--RSRSPKENGKGDIKSKSRSRSQSR 300
R S+S P+ R + RSRS ++RSR+ R R + KSRS + R
Sbjct: 1688 -RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746
Query: 301 SNSPLPVPPSKARSVSPPPK-RATSRSRSRSRSK----SRSRSRSSS 342
S S + R SP PK R RSRSRSR + +R R RS S
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793
Score = 69.7 bits (169), Expect = 4e-12
Identities = 59/176 (33%), Positives = 81/176 (46%), Gaps = 19/176 (10%)
Query: 184 RTSHRRSYSGSRSRSRSRRRS---RSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG 240
RT RR SGS S +++ R+ RSRS S + IS RSRS S + +++SR
Sbjct: 716 RTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSL 775
Query: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR--SRSQ 298
R+S S S PK + RSRS K++SR+ R + + K KS+ SR
Sbjct: 776 RRSLSGSSPCPKQ-KSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
Query: 299 SRSNSPLP-----VPPSKARSVSP--------PPKRATSRSRSRSRSKSRSRSRSS 341
S+SP P PP + SP P +R+ S KSR+ SR S
Sbjct: 835 HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS 890
Score = 67.8 bits (164), Expect = 1e-11
Identities = 76/288 (26%), Positives = 119/288 (41%), Gaps = 30/288 (10%)
Query: 74 RRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQA 133
RR R G S G R G G S SG P ++ R S S + K +
Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGS---SPGMKDIPRTPSRGRSECDSSPEPKALPQTP 1493
Query: 134 GEVTYADAHKERTNEGVIEFRSYSDMKRALDKLD------GTEINGRNIRLIEDKPRTSH 187
+ + + E N+ + R S + ++D+ G + + ++ KP S
Sbjct: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553
Query: 188 RRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKS 247
+ RS S S S++++R R RSRS S S+SR R + + K
Sbjct: 1554 Q-----ERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
Query: 248 KSKPKSDRGSHSHSR-----SRSKDEYEKSRSRSRSRSPKENGKGDIKSK----SRSRSQ 298
++ P++ GS S R+ +S S S+ R P G +S +SR+
Sbjct: 1609 RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTA 1668
Query: 299 SRSNSPLPVPPSKARSVSPPPKRATSRS----RSRSRSKSRSRSRSSS 342
R + P P +K+R+ PP+R +SRS ++R RSRS SSS
Sbjct: 1669 RRGSRSSPEPKTKSRT---PPRRRSSRSSPELTRKARLSRRSRSASSS 1713
Score = 66.6 bits (161), Expect = 3e-11
Identities = 63/176 (35%), Positives = 82/176 (46%), Gaps = 22/176 (12%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR 241
K R S R + S +RSR R R R S S KSRS R RS R+++ R
Sbjct: 1700 KARLSRRSRSASSSPETRSRTPPRHR-RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758
Query: 242 KSRSKSKSKPKSDRGSHSHSRSRSKDEYEK-SRSRSRSRSPKENGKGDIKSKSRSRSQSR 300
+ RS S KP+ + SRSRS+ E + +R R RS S + + +S+SRSR R
Sbjct: 1759 RGRSPSP-KPRGLQ----RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813
Query: 301 --------SNSPLPVPPS-------KARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
S SP S + RS +PP R SRSR+ RSRSR+S
Sbjct: 1814 RRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS 1869
Score = 63.2 bits (152), Expect = 3e-10
Identities = 43/162 (26%), Positives = 66/162 (40%), Gaps = 1/162 (0%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR 241
K + ++ G RS S S RR R +S + + RS S SK R K + +S+ K R
Sbjct: 186 KQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKR 245
Query: 242 KSRSKSKSKPKSDRGSHSHSR-SRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR 300
K + PKS R S S S S + +SRSRS + S +
Sbjct: 246 KRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGE 305
Query: 301 SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
++P P + + P+ AT + S K + + S+
Sbjct: 306 GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA 347
Score = 62.8 bits (151), Expect = 4e-10
Identities = 51/169 (30%), Positives = 78/169 (46%), Gaps = 13/169 (7%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR 241
KP + R S S SRS + +++ + + R RS S S + R +S + K RS S SK R
Sbjct: 169 KPYSLVRES-SSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR 227
Query: 242 KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPK-ENGKGDIKSKSRSRSQS- 299
K RS + PKS R S R RS+ +SR RS ++ S+SRSRS +
Sbjct: 228 KHRSPT---PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAA 284
Query: 300 -------RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
SP P + +P + T+ ++ S ++ ++ SS
Sbjct: 285 KTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSS 333
Score = 62.4 bits (150), Expect = 6e-10
Identities = 74/215 (34%), Positives = 96/215 (44%), Gaps = 52/215 (24%)
Query: 180 EDKPRTSHRRSYSGSR--------SRSRSRRRSRSRSRRSSR-SRSRSISKS-------- 222
++K RTS RRS S S S RSR S RS+ SR S RS+S S
Sbjct: 731 KNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKS 790
Query: 223 -----RSRSRSRSKGRSRSRSKGRKSRSKSKSKPKS-----DRGSHSHSRSRSKDEYEKS 272
RSRS S S+ +++SR+ R+SRS S PK R SHS S K +
Sbjct: 791 QTPPRRSRSGS-SQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP 849
Query: 273 RSRSRSRSPKENGKG---------------DIKSKSRSRSQSRSNSPLPV----PP--SK 311
+ SP+ N + ++KS++ SR +SP V PP S
Sbjct: 850 PRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909
Query: 312 ARSVSPPPK---RATSRSRSRSRSKSRSRSRSSSR 343
+RS SP PK + R RS S S S S SR +SR
Sbjct: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR 944
Score = 61.2 bits (147), Expect = 1e-09
Identities = 53/161 (32%), Positives = 67/161 (41%), Gaps = 4/161 (2%)
Query: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
P+ + R + ++ +RRS S S SS S S S S S S S S S S S S
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
Query: 243 SRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSN 302
S S S +KP G + + S + RSRS + D +S S S + R
Sbjct: 2646 SSSPSPAKP----GPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRP 2701
Query: 303 SPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
SP P P + S S R R SRS S R R S R
Sbjct: 2702 SPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 5/143 (3%)
Query: 190 SYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS 249
SY S RR ++ + S+ + S SRS + + + + K + R S
Sbjct: 144 SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESS 203
Query: 250 KPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPP 309
P+ +R S + + + E E + + RS +PK K SK + R +SRS +P P
Sbjct: 204 SPRRER-KKSSKKKKHRSESESKKRKHRSPTPKSKRK----SKDKKRKRSRSTTPAPKSR 258
Query: 310 SKARSVSPPPKRATSRSRSRSRS 332
RS S ++ SRSRSRS
Sbjct: 259 RAHRSTSADSASSSDTSRSRSRS 281
Score = 59.3 bits (142), Expect = 5e-09
Identities = 66/231 (28%), Positives = 103/231 (44%), Gaps = 44/231 (19%)
Query: 142 HKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIED-----KPRTSHRRSYSGSRS 196
+K RT++ S +MK++ I+ R R + K R S RRS SGS
Sbjct: 732 NKSRTSQRRSRSNSSPEMKKS-------RISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Query: 197 RSRSRRRSRSRSRRSSRSRSRSISKS---RSRSRSRSKGRSRSRSKGRKSRSKSKSKPKS 253
+ + ++ R RS S+ ++ S++ RSRS S + +S++ R+S S S PK
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKV 844
Query: 254 DRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKG-DIKSKSRSR---------------- 296
G+ S + + + + RS E+ ++KS++ SR
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP 904
Query: 297 ---SQSRSNSPLP-----VPP---SKARSVSPPPKRATSRSRSRSRSKSRS 336
S SRS+SP P + P S + S SP P R TSR+ R RS+S S
Sbjct: 905 PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR-RSRSVS 954
Score = 56.6 bits (135), Expect = 3e-08
Identities = 58/204 (28%), Positives = 84/204 (41%), Gaps = 50/204 (24%)
Query: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRS-------RRSSRSRSRSISKSRSRSRSRSK-- 231
+ + HR S+ +S+ ++R RSRS RR+ RS S + S SRSRS+
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
Query: 232 ----------GRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSP 281
GRS S + GR+ + P S+ G+ S R S + K S SP
Sbjct: 283 AAKTHTTALAGRSPSPASGRRGEGDA---PFSEPGTTSTQRPSSPETATKQPS-----SP 334
Query: 282 KENGKGDIKSKSRSR---SQSRSNS--------------------PLPVPPSKARSVSPP 318
E+ D K KS +R S RS++ PL P V+PP
Sbjct: 335 YEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP 394
Query: 319 PKRATSRSRSRSRSKSRSRSRSSS 342
+ + +R RS +S + SSS
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSS 418
Score = 56.6 bits (135), Expect = 3e-08
Identities = 55/157 (35%), Positives = 73/157 (46%), Gaps = 26/157 (16%)
Query: 184 RTSHRRSYSGSRSRSRSR------RRSRSRS----RRSSRSRSRSISKSRSRSRSRSKGR 233
R S R+ +R RSRSR RRSRSR+ RR SRSR+ + + RSRSRS R
Sbjct: 1992 RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIR 2051
Query: 234 SRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293
RSRS+ P++ RG S +RS R RS S S + + +
Sbjct: 2052 RRSRSR----------TPRTARGKRSLTRSP-----PAIRRRSASGSSSDRSRSATPPAT 2096
Query: 294 RSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRS 330
R+ S SR+ P+ + S+ S P T R RS
Sbjct: 2097 RNHSGSRT-PPVALNSSRMSCFSRPSMSPTPLDRCRS 2132
Score = 53.5 bits (127), Expect = 3e-07
Identities = 57/175 (32%), Positives = 81/175 (46%), Gaps = 21/175 (12%)
Query: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRS-RSISKSRSRSRSR--SKGRSRSRSK 239
PRT RRS SGS R + SR S S + I ++ SR RS S ++ +
Sbjct: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSR---------SRSRSRSPKENGKGDIK 290
+ RS+S S P+ + + R RS E + RSRS S +E D+K
Sbjct: 1492 TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL---DVK 1548
Query: 291 SKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSR---SRSRSSS 342
+ + +S S+S P SKA++ +P +R+ S S SKSR RSRS S
Sbjct: 1549 PSASPQERSESDSS---PDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGS 1600
Score = 51.2 bits (121), Expect = 1e-06
Identities = 50/149 (33%), Positives = 69/149 (46%), Gaps = 13/149 (8%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRS---RSRSISKSRSRSRSRSKGRSRSRS 238
K RT RRS S S + + ++ SR SS S + +S + R S + + +S +
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT 866
Query: 239 KGRKSRSKSKSKPK-SDRGSHSHSRSRSKDEYEKS-----RSRSRSRSPKENGKGDIKSK 292
R+S +S P+ R HS S S KS +S SRS SP+ K I +
Sbjct: 867 PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPR 926
Query: 293 SRSRSQSRSNSPLPV----PPSKARSVSP 317
RS S S S SP V P ++RSVSP
Sbjct: 927 QRSHSGSSSPSPSRVTSRTTPRRSRSVSP 955
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/141 (35%), Positives = 66/141 (46%), Gaps = 12/141 (8%)
Query: 184 RTSHRRSYSGSRSRSRS------RRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSR 237
R S R+ +R RSRS RRRSRSR+ R RSRS S R RSRS+ +R
Sbjct: 2004 RRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTAR 2063
Query: 238 SKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRS 297
K +RS + +S GS S RSRS +R+ S SR+P + S S
Sbjct: 2064 GKRSLTRSPPAIRRRSASGS-SSDRSRSATP-PATRNHSGSRTPPV----ALNSSRMSCF 2117
Query: 298 QSRSNSPLPVPPSKARSVSPP 318
S SP P+ ++ + P
Sbjct: 2118 SRPSMSPTPLDRCRSPGMLEP 2138
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/138 (34%), Positives = 60/138 (43%), Gaps = 8/138 (5%)
Query: 213 RSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKS 272
RS +S K S S S S +K + S S PK SH R S K+
Sbjct: 403 RSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH-REISSSPTSKN 461
Query: 273 RSRSRSRSPKENGKGDIKSKSRSRS-----QSRSNSPLPVPPSKARSVSPPPKRATSRSR 327
RS R++ K + + RSRS + RS S P +RS SP +R+ S R
Sbjct: 462 RSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR 521
Query: 328 -SRSRS-KSRSRSRSSSR 343
RSRS + R RSRS R
Sbjct: 522 WGRSRSPQRRGRSRSPQR 539
Score = 49.7 bits (117), Expect = 4e-06
Identities = 51/169 (30%), Positives = 71/169 (42%), Gaps = 20/169 (11%)
Query: 194 SRSRSRSRRRSRSRSRRSSRSRSRSISKSRSR--SRSRSKGRSRSRSKGRKSRSKSKSKP 251
S +R RS +S + +SS S S S ++ + S S + S + S P
Sbjct: 398 SPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSP 457
Query: 252 KSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS-RSRSQSRSNSP------ 304
S SH ++ + SR RSRSP +G +S++ R SRS SP
Sbjct: 458 TSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSR 517
Query: 305 -------LPVPPSKARSVSPPPKRATSRSRS---RSRSKSRSRSRSSSR 343
P + RS S P + SRSR+ R RS+S R RS SR
Sbjct: 518 SAQRWGRSRSPQRRGRSRS-PQRPGWSRSRNTQRRGRSRSARRGRSHSR 565
Score = 48.1 bits (113), Expect = 1e-05
Identities = 52/166 (31%), Positives = 58/166 (34%), Gaps = 32/166 (19%)
Query: 203 RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG---------------------- 240
+ R S SS S S S S S S S S S G S S S+G
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 241 ---RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRS 297
R+ R + K R S S S S S S S S S S + S S S S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----SSSSSSS 2642
Query: 298 QSRSNSPLPVPPSKARSVSP--PPKRATSRSRSRSRSKSRSRSRSS 341
S S+SP P P P P K RSRS K R S
Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 24/129 (18%)
Query: 237 RSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSR-----SPKENGKGDIKS 291
R++ K + KP S S SRS + + +K + + R R SP+ K K
Sbjct: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215
Query: 292 KSRSRSQSRSNS---PLPVPPSK----------ARSVSPPPK-----RATSRSRSRSRSK 333
K + RS+S S P P SK +RS +P PK R+TS + S
Sbjct: 216 K-KHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
Query: 334 SRSRSRSSS 342
SRSRSRS++
Sbjct: 275 SRSRSRSAA 283
Score = 42.4 bits (98), Expect = 6e-04
Identities = 30/94 (31%), Positives = 35/94 (37%)
Query: 249 SKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVP 308
+K + S S S S S S S S S S + +G + R SP P P
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586
Query: 309 PSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
R PP R R S S S S S SSS
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/147 (29%), Positives = 69/147 (46%), Gaps = 9/147 (6%)
Query: 182 KPRTSHRRSYSGSRS---RSRSRRRSRSRSRRSSRSRSRSISKS---RSRSRSRSKGRSR 235
K T SY G S + +S+ RS SS +S S+S +S+S++ KG R
Sbjct: 1040 KSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKG-GR 1098
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHS-RSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
SRS + S+S + DRG S S +S E+SR +S S S + +SR
Sbjct: 1099 SRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSR 1158
Query: 295 SRSQSRSNSPLPVPPSKARSVSPPPKR 321
+ + S + +PP + + SPP ++
Sbjct: 1159 LET-AESKEKMALPPQEDATASPPRQK 1184
Score = 41.2 bits (95), Expect = 0.001
Identities = 51/177 (28%), Positives = 68/177 (38%), Gaps = 30/177 (16%)
Query: 197 RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKS----KSKPK 252
R+ SR RS S S + RSRS S R S + R S S S K P+
Sbjct: 1412 RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR 1471
Query: 253 SDRGSHSHSRSRSKDEYEKSRSRSRSRSPKE---NGKGDIKSKSRS-------------- 295
+ S S + + R RSRSP N K + RS
Sbjct: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVART 1531
Query: 296 ----RSQSRSNSPLPVPPS-----KARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
RS+S S+ L V PS ++ S S P +A +R+ R RS+S S S+
Sbjct: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK 1588
Score = 39.3 bits (90), Expect = 0.005
Identities = 44/128 (34%), Positives = 56/128 (43%), Gaps = 17/128 (13%)
Query: 222 SRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRS--------KDEYEKSR 273
+RS S S+ + K S ++S S P D + SR RS KD ++
Sbjct: 1376 TRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435
Query: 274 SRSRSRSPKENGKGDIKSKSRSRSQSRSNSP----LPVPPSKARS---VSPPPKRATSRS 326
SR RSRS G D S + SR +SP +P PS+ RS SP PK
Sbjct: 1436 SR-RSRSGSSPGLRD-GSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTP 1493
Query: 327 RSRSRSKS 334
R RSRS S
Sbjct: 1494 RPRSRSPS 1501
Score = 38.9 bits (89), Expect = 0.007
Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 34/191 (17%)
Query: 180 EDKPRTSHRRSYSGS--RSRSRSRRRSRSRSRRSSRSRSRSIS---------------KS 222
+ K +T R+S+S S + +S R S S ++ +S++ KS
Sbjct: 824 KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS 883
Query: 223 RSRSRSRSKGRSRSRSKG----RKSRSKSKS---------KPKSDRGSHSHSRSRSKDEY 269
R+ SR G S R K R+S S+S S P+ S S S S S+
Sbjct: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTS 943
Query: 270 EKSRSRSRSRSPKENGKGDIKSK-SRSRSQSRSNSPLPVPP---SKARSVSPPPKRATSR 325
+ RSRS SP N + + + S S S S P P S + S+SP PK
Sbjct: 944 RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT 1003
Query: 326 SRSRSRSKSRS 336
S S S+S
Sbjct: 1004 PPGPSLSGSKS 1014
Score = 37.7 bits (86), Expect = 0.015
Identities = 56/178 (31%), Positives = 74/178 (41%), Gaps = 32/178 (17%)
Query: 188 RRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK------GR 241
+RS+SGS S S SR SR+ RRS S +SR R G S +K R
Sbjct: 927 QRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPR 986
Query: 242 KSRSKS-----KSKPKSDRGSHSHSRSRSKDEYEKSRSR---------------SRSRSP 281
+S S S K K ++ G S S S+S EKS+ S P
Sbjct: 987 QSHSGSISPYPKVKAQTPPGP-SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP 1045
Query: 282 KENGKG----DIKSKSRSRSQSRSNSPLP-VPPSKARSVSPPPKRATSRSRSRSRSKS 334
E+ G +K +S++ RS++ P V S + S S K TS RSRS S
Sbjct: 1046 GESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSS 1103
Score = 35.8 bits (81), Expect = 0.057
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 16/97 (16%)
Query: 250 KPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPP 309
+P +R S S S S S S S S S S S S S S LPV P
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSS------------SSSGSSSSDSEGSSLPVQP 2572
Query: 310 ----SKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
+ S +P PK A R + ++ + RSSS
Sbjct: 2573 EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSS 2609
Score = 33.9 bits (76), Expect = 0.22
Identities = 45/147 (30%), Positives = 48/147 (32%), Gaps = 45/147 (30%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSK-------- 231
E P RRS S S S S S S S S SS S S S S S S S S S
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
Query: 232 --------------GRSRSRSKG------RKSRSKSKS-----------------KPKSD 254
G RSRS R SRS S S S+
Sbjct: 2657 QALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSE 2716
Query: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSP 281
RGS R S+ K R + S P
Sbjct: 2717 RGSRRGQRGDSRSPSHKRRRETPSPRP 2743
Score = 32.0 bits (71), Expect = 0.83
Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 2/141 (1%)
Query: 203 RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSR 262
R+RSR+ S+ S+SR S+ R+ S S G++ S+S ++ + +S S S
Sbjct: 2404 RARSRTPPSAPSQSRMTSE-RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCL 2462
Query: 263 SRSKDEYEKSRSRSRSR-SPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKR 321
S+S S + + GD + +S + PP+ + P
Sbjct: 2463 IAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALA 2522
Query: 322 ATSRSRSRSRSKSRSRSRSSS 342
A ++ R S S S S SSS
Sbjct: 2523 ALQPAKERRSSSSSSSSSSSS 2543
Score = 31.2 bits (69), Expect = 1.4
Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 277 RSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSK-------ARSVSPPPKRATSRSRSR 329
R+R K+ K S R S S SP P K RS S P+R R +S
Sbjct: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRR--ERKKSS 213
Query: 330 SRSKSRSRSRSSSR 343
+ K RS S S R
Sbjct: 214 KKKKHRSESESKKR 227
Score = 28.5 bits (62), Expect = 9.2
Identities = 24/87 (27%), Positives = 33/87 (37%), Gaps = 13/87 (14%)
Query: 270 EKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPP---------SKARSVSPPPK 320
EK R R+ + D S R + P P PP S +RS +P K
Sbjct: 129 EKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQK 188
Query: 321 RATSRS----RSRSRSKSRSRSRSSSR 343
+ + RS S S R R +SS +
Sbjct: 189 KKKKKKDRGRRSESSSPRRERKKSSKK 215
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 97.8 bits (242), Expect = 1e-20
Identities = 78/198 (39%), Positives = 104/198 (52%), Gaps = 40/198 (20%)
Query: 186 SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSR------SISKSRSRSRSRSKGRSRSRSK 239
S RRS SGS+ R+ SR RS S R SR+RSR S S+SRS SKG+S+++S+
Sbjct: 286 SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR 345
Query: 240 G-RKSRSKSKSKPKSDRGSHSHSRSRSKDEYE-------------------KSRSRSRSR 279
R+ RS + S+ S SHSHSRS SK+ K R SRSR
Sbjct: 346 TPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSR 405
Query: 280 SP-----KENGKGDIKSKSRSRSQ--------SRSNSPLPVPPSKARSVSPPPKRATSRS 326
SP + + K++ RSRS+ SRS SP ++RS SP R SRS
Sbjct: 406 SPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKA-RDRSRSRSPNKARDHSRS 464
Query: 327 RSRSRSKSRSRSRSSSRD 344
RS ++++ RSRSRS S++
Sbjct: 465 RSPNKARDRSRSRSPSKE 482
Score = 95.5 bits (236), Expect = 6e-20
Identities = 73/175 (41%), Positives = 94/175 (53%), Gaps = 28/175 (16%)
Query: 189 RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR------------SRS 236
RS S S+SRS RRSRS S++ + SR RS S R+ SR+RS+ R SRS
Sbjct: 275 RSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRS 334
Query: 237 RSKG---------RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKG 287
SKG R+ RS + S+ S SHSHSRS SK+ + S R KE+G+
Sbjct: 335 HSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR----KESGRS 390
Query: 288 DIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
S ++ R SRS SP ++ RS S P +A RSRSRS +K+R SRS S
Sbjct: 391 QSGSPNKQRDHSRSRSP---NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS 442
Score = 91.3 bits (225), Expect = 1e-18
Identities = 95/296 (32%), Positives = 129/296 (43%), Gaps = 36/296 (12%)
Query: 69 HARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKD 128
H+R R R G S G +S R+ + K RT R N S S +
Sbjct: 311 HSRARSRTRKGIL----SQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHS 366
Query: 129 FMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRA------LDKLDGTEINGRNIRLIEDK 182
R + KER + G R S ++ D N R
Sbjct: 367 HSRSSS--------KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
Query: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
P + RS S S +++R RSRS + RSRSRS +K+R SRSRS ++R RS+
Sbjct: 419 PYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR--- 475
Query: 243 SRSKSKSKPKSDRGS------HSHSRSRSKDEY-------EKSRSRSRSRSP-KENGKGD 288
SRS SK + S GS H SRS SK+ K R RSRSP KE +
Sbjct: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ 535
Query: 289 IKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
+S ++ R +S+S SP + +S SP +R R RS S+ + R +SRSSS +
Sbjct: 536 SRSPNKERDRSQSRSPSEEREHR-QSRSPSKERDRRRWRSPSKERERRQSRSSSEE 590
Score = 90.1 bits (222), Expect = 3e-18
Identities = 90/290 (31%), Positives = 127/290 (43%), Gaps = 22/290 (7%)
Query: 70 ARGPRRDRD-GYSYGS---RSGGGGYSSRRTSGRDKYGPP------VRTEYRLIVENLSS 119
+R P ++R +S S R G S R+ SGR + G P R+ + S
Sbjct: 356 SRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSR 415
Query: 120 RCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLI 179
S +D R D + R+ + +A D N R
Sbjct: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSR----RSSRSRSRSISKSRSRSRSRSKGRSR 235
P S GS S+ R RRSRS S+ R SRS S+ RSRS S+ + R +
Sbjct: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ 535
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSP-KENGKGDIKSKSR 294
SRS K R +S+S+ S+ H SRS SK+ R R R RSP KE + +S S
Sbjct: 536 SRSP-NKERDRSQSRSPSEEREHRQSRSPSKE-----RDRRRWRSPSKERERRQSRSSSE 589
Query: 295 SRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
R SRS SP +R + ++A SRSR+ S+ + S+SR+SS++
Sbjct: 590 ERDHSRSRSP-NKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKE 638
Score = 84.7 bits (208), Expect = 1e-16
Identities = 60/165 (36%), Positives = 89/165 (53%), Gaps = 17/165 (10%)
Query: 187 HRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR---KS 243
HRRS S S+ R R R+SRS ++ RS+SRS S+ R +SRS + R R + R K
Sbjct: 521 HRRSRSPSKERQR--RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE 578
Query: 244 RSKSKSKPKSDRGSHSHSRSRSKDE-------YEKSRSRSRSRSPKENGKGDIKSKSRSR 296
R + +S+ S+ HS SRS +K K ++ SRSR+P + G +S++ S+
Sbjct: 579 RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHS-QSRTSSK 637
Query: 297 SQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
S S +P P RS P R +S S++R+ SK+ S S S+
Sbjct: 638 ESDPSQSTVPRSPDWKRS----PTRTSSLSQNRTPSKTSSHSPST 678
Score = 80.1 bits (196), Expect = 3e-15
Identities = 62/172 (36%), Positives = 94/172 (54%), Gaps = 22/172 (12%)
Query: 186 SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR---- 241
S +SYS + SR + S ++ S+RSR +S S+SRS RSRS + R+ S+ R
Sbjct: 252 SREKSYSPTEMSSRVK----SYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSW 307
Query: 242 -----KSRSKSKSKPKSDRGSHSHSRSRSKDEYE-------KSRSRSRSRSP-KENGKGD 288
++RS+++ S G HS SRS SK + + + RS + SR+P KE
Sbjct: 308 KRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367
Query: 289 IKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRS 340
+S S+ R S+SP +++S SP +R SRSRS ++++ RSRSRS
Sbjct: 368 SRSSSKERDHRGSSSPRK-ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
Score = 57.4 bits (137), Expect = 2e-08
Identities = 55/180 (30%), Positives = 82/180 (45%), Gaps = 22/180 (12%)
Query: 166 LDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRS-RSRRRSRSRSRRSSRSRSRSISKSRS 224
L T+ N L+ KP TS S S S+S +S R+ S R S SRSR SK+R+
Sbjct: 32 LKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPS-SRSRVRSKART 90
Query: 225 RSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKEN 284
SR + R+ SK R + RG+HS R+ + SRS RSP
Sbjct: 91 PSRVSTDTRTSKASKASDVRCHQR------RGTHSRGRTPG-----RRGSRSSKRSP--- 136
Query: 285 GKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
S++ + + R++ P S+ R+ + K + +S R R+ +R RS S R+
Sbjct: 137 ------SRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN 190
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/186 (27%), Positives = 78/186 (41%), Gaps = 29/186 (15%)
Query: 187 HRRSYSGSRSRSRSRRRSRSRSRRSSR-----------------SRSRSISKSRSRSRSR 229
H+R + SR R+ RR SRS R SR SR R+ + + SR +
Sbjct: 112 HQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGK 171
Query: 230 SKGRSRSRSKGR-----KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSR------SRSRS 278
S GR R+ ++ R ++ SK +P G S K + S+ +S
Sbjct: 172 SYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKS 231
Query: 279 RSPKENGKGDIKSKSRSRSQSRSNSPLPVP-PSKARSVSPPPKRATSRSRSRSRSKSRSR 337
+P + +KS + SR S P S+ +S + R+ +S S+SRS RSR
Sbjct: 232 DNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSR 291
Query: 338 SRSSSR 343
S S R
Sbjct: 292 SGSQKR 297
Score = 48.9 bits (115), Expect = 7e-06
Identities = 46/179 (25%), Positives = 84/179 (46%), Gaps = 19/179 (10%)
Query: 172 NGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSK 231
+G ++ + KP S + + S + +RS + + SR+ +S S S+S ++S
Sbjct: 17 SGSSMPTADPKPPASLKSTKSATPNRSLV-------PTKPATSRNSVMSPSSSKS-TKST 68
Query: 232 GRSRSRSKGRKSRSKSKSKPK------SDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENG 285
R+ S SRS+ +SK + +D + S++ +++ + SR R+P G
Sbjct: 69 STKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRG 128
Query: 286 KGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
S+S RS SR+++P + AR R + + SR KS R R+S+R+
Sbjct: 129 -----SRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRE 182
Score = 46.2 bits (108), Expect = 4e-05
Identities = 62/197 (31%), Positives = 84/197 (42%), Gaps = 37/197 (18%)
Query: 184 RTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRS--RSRSKG-----RSRS 236
RTS S R R SR R+ SRS S SR+ + R R+ G SR
Sbjct: 99 RTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRV 158
Query: 237 R---SKGRKSRSKSKSKPKSDRGSHSHSRSR--SKDEYEKSRSRSRSRS---------PK 282
R S+ + SR KS +P++ S S+ R SK Y RS K
Sbjct: 159 RTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAK 218
Query: 283 ENGKGDIKSKSRSRSQSRSNS------PLPVPPSKARSVSPPP--------KRATSRSRS 328
I SK +S + S S+S + PS+ +S SP +A++RSR
Sbjct: 219 CQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRP 278
Query: 329 RSRSKSRS--RSRSSSR 343
+S S+SRS RSRS S+
Sbjct: 279 QSHSQSRSPRRSRSGSQ 295
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 93.6 bits (231), Expect = 2e-19
Identities = 96/296 (32%), Positives = 131/296 (44%), Gaps = 49/296 (16%)
Query: 6 IGRLSYNVREKDIQRFFSGYGRLLEVDLKN--------GYGFVEFEDSRDADDAVYELNG 57
+ L+Y ++R F YGR+ +V + G+ FV F D RDA DA ++G
Sbjct: 18 VDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDG 77
Query: 58 KELCGERVIVEHARGPRRD----RDGYSYGSRSGGGGYSSR-RTSGRDKYGPPVRTEYRL 112
EL G + V+ AR RRD R G G RS GGGY R R+ GR P R R
Sbjct: 78 AELDGRELRVQVARYGRRDLPRSRQGEPRG-RSRGGGYGRRSRSYGRRSRSPRRRHRSR- 135
Query: 113 IVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEIN 172
+ CS R Y + R+ YS + + + +
Sbjct: 136 ---SRGPSCS--------RSRSRSRYRGSRYSRS--------PYSRSPYSRSRYSRSPYS 176
Query: 173 GRNIRLIEDKPRTSHRRS--YSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRS 230
R E + SH S YS SR RS S+S S+ SRS S SKS S RS+S
Sbjct: 177 RSRYR--ESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKS 234
Query: 231 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGK 286
SRSRS+ R S S ++S P+ S+ +SK +SRS+ +SP+E G+
Sbjct: 235 SSVSRSRSRSRSS-SMTRSPPRV-------SKRKSK---SRSRSKRPPKSPEEEGQ 279
Score = 91.3 bits (225), Expect = 1e-18
Identities = 91/269 (33%), Positives = 121/269 (44%), Gaps = 41/269 (15%)
Query: 104 PPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEG-----VIEFRSYSD 158
P V L V+NL+ R S L+ + G V +E + + F D
Sbjct: 8 PDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRD 67
Query: 159 MKRALDKLDGTEINGRNIRLI-------------EDKPRTSHRRSYSGSRSRSRSRRRSR 205
+ A +DG E++GR +R+ + +PR R G RSRS RR
Sbjct: 68 AQDAEAAMDGAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRS 127
Query: 206 SRSRRSSRSRSRSISKSRSRSRSRSKGRSRS------RSKGRKSRSK-SKSKPKSDR--G 256
R R SRSR S S+SRSRSR R SRS S+ R SRS S+S+ + R G
Sbjct: 128 PRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGG 187
Query: 257 SHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVS 316
SH S S Y SR S + + K + SRS S S+S+S SK+ SVS
Sbjct: 188 SHYSSSGYSNSRY------SRYHSSRSHSKSGSSTSSRSASTSKSSS---ARRSKSSSVS 238
Query: 317 PPPKRATSRSRSR-----SRSKSRSRSRS 340
R+ S S +R S+ KS+SRSRS
Sbjct: 239 RSRSRSRSSSMTRSPPRVSKRKSKSRSRS 267
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 91.7 bits (226), Expect = 9e-19
Identities = 70/189 (37%), Positives = 90/189 (47%), Gaps = 37/189 (19%)
Query: 188 RRSYSGSRSRSRSRRRSRSRSRRS-----------SRSRSRSISKSRSRSRSRSKGRSRS 236
RRS S R RSRSR R R RR R R R K R R + + RSR
Sbjct: 328 RRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRE 387
Query: 237 RSKGRKSRSKSKSKP----KSDRGSHS----------HSRSRSKDEYEKSRSRSR----- 277
RSK ++SR + + K K DR HSRSRS++ +SRSRSR
Sbjct: 388 RSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR 447
Query: 278 --SRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSR 335
SRS +++ K +SK +S +SRS S + SV KR S S+ +SR +SR
Sbjct: 448 SRSRSKEKSSKHKNESKEKSNKRSRSGSQ-----GRTDSVEKSKKREHSPSKEKSRKRSR 502
Query: 336 SRSRSSSRD 344
S+ RS RD
Sbjct: 503 SKERSHKRD 511
Score = 82.8 bits (203), Expect = 4e-16
Identities = 60/184 (32%), Positives = 89/184 (48%), Gaps = 27/184 (14%)
Query: 182 KPRTSHRRSYSGS-------RSRSRSRRRSRSRSRRSSRSRSRSISKS--RSRSRSRSKG 232
+ R+ HR + S R + R R ++ R R RSRSI + R RSRSR +
Sbjct: 277 RSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERH 336
Query: 233 RSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD-----EYEKSRSRSRSRSPKENGKG 287
RSRSRS+ RK + + + + R R D E EK R RSR RS ++ +G
Sbjct: 337 RSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRG 396
Query: 288 DIKSKS-------RSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRS---RSKSRSR 337
+++ K R + +S S++RS ++ SRSRSR+ RS+SRS+
Sbjct: 397 EVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRE---RKHRSRSRSRNAGKRSRSRSK 453
Query: 338 SRSS 341
+SS
Sbjct: 454 EKSS 457
Score = 80.1 bits (196), Expect = 3e-15
Identities = 83/271 (30%), Positives = 124/271 (45%), Gaps = 47/271 (17%)
Query: 75 RDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAG 134
++R+ SRS G RR+ R+++ R+ R R ++ + G
Sbjct: 309 KEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRK-----GDRRDRDREREKENERG 363
Query: 135 EVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGS 194
D KER NE E +R+ ++ E+ + + EDK HR
Sbjct: 364 RRRDRDYDKERGNER--EKERERSRERSKEQRSRGEVEEKKHK--EDKDDRRHRDD---- 415
Query: 195 RSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKG-RSRSRSKGRKSRSKSKSKPKS 253
+R + ++ SRSRSR K RSRSRSR+ G RSRSRSK + S+ K++SK KS
Sbjct: 416 -------KRDSKKEKKHSRSRSRE-RKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKS 467
Query: 254 DRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKAR 313
++ S S S+ R+ D EKS+ R S S + KS+ RSRS+ RS+
Sbjct: 468 NKRSRSGSQGRT-DSVEKSKKREHSPSKE-------KSRKRSRSKERSH----------- 508
Query: 314 SVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
KR S S+ +S R RS+S ++
Sbjct: 509 ------KRDHSDSKDQSDKHDRRRSQSIEQE 533
Score = 71.6 bits (174), Expect = 9e-13
Identities = 72/219 (32%), Positives = 102/219 (46%), Gaps = 44/219 (20%)
Query: 68 EHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLK 127
E+ RG RRDRD Y R + R+K E SR +
Sbjct: 359 ENERGRRRDRD------------YDKERGNEREK-------------ERERSR----ERS 389
Query: 128 DFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSH 187
R GEV HKE ++ R + D KR K E R E K R+
Sbjct: 390 KEQRSRGEVE-EKKHKEDKDD-----RRHRDDKRDSKK----EKKHSRSRSRERKHRSRS 439
Query: 188 RRSYSGSRSRSRSRRRS---RSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSR 244
R +G RSRSRS+ +S ++ S+ S RSRS S+ R+ S +SK R S SK KSR
Sbjct: 440 RSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSK-EKSR 498
Query: 245 SKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKE 283
+S+SK +S + HS S+ +S D++++ RS+S + +E
Sbjct: 499 KRSRSKERSHKRDHSDSKDQS-DKHDRRRSQSIEQESQE 536
Score = 45.4 bits (106), Expect = 7e-05
Identities = 42/137 (30%), Positives = 57/137 (41%), Gaps = 30/137 (21%)
Query: 209 RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDE 268
++ + + I + R RSRS RS S + + RS+S+S + GS S R E
Sbjct: 241 KKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPR-RSRSRSHHREGHGSSSFDR-----E 294
Query: 269 YEKSRSRSR-SRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSR 327
E+ + R R R KE K +S+S R R RSR
Sbjct: 295 LEREKERQRLEREAKEREKERRRSRSIDRGLERR-----------------------RSR 331
Query: 328 SRSRSKSRSRSRSSSRD 344
SR R +SRSRSR D
Sbjct: 332 SRERHRSRSRSRDRKGD 348
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 90.9 bits (224), Expect = 2e-18
Identities = 76/170 (44%), Positives = 97/170 (57%), Gaps = 18/170 (10%)
Query: 185 TSHRRSYSGSRSRSRSRRRS-RSRSRRSSRSRSRS---ISKSRSRSRSRSKGRSRSRSKG 240
++ RRS S S S S SR S RS SR SSRSR S +RSRSRS RSRSRS+
Sbjct: 372 SARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSR- 430
Query: 241 RKSRSKSKSKPKSDRGS---HSHSRSRSKDEYEKSRSRSRSRSP-----KENGKGDIKSK 292
R SRS+S+ + S GS H +SRS ++ R RSRSRS + G+G
Sbjct: 431 RYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRG----- 485
Query: 293 SRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
R S SRS S + PS++RS++ + S S+SRSRS+SRS+S S S
Sbjct: 486 LRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPS 535
Score = 85.5 bits (210), Expect = 6e-17
Identities = 73/162 (45%), Positives = 86/162 (53%), Gaps = 28/162 (17%)
Query: 184 RTSHRRSYSGSRSRSR-------SRRRSRSRSRRSSRSRSRS--ISKSRSRSRSRSKGRS 234
RTS RS S S SRSR S R +RSRSR SRSRSRS S+SRSR R S G S
Sbjct: 388 RTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGS 447
Query: 235 R-----SRSKG--------RKSRSKSKSKPKSDRGS-----HSHSRSRSKDEYEKSRSRS 276
R SRS R+SRS+S S + RG HS SRSRS SRSRS
Sbjct: 448 RDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRS 507
Query: 277 RSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPP 318
+RS + + +S+SRSRS+S+S SP P R + P
Sbjct: 508 LTRS-RSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASP 548
Score = 70.9 bits (172), Expect = 2e-12
Identities = 72/182 (39%), Positives = 86/182 (47%), Gaps = 23/182 (12%)
Query: 131 RQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRS 190
R+ + + + RT+ RS S +R G +GR+ R S RS
Sbjct: 374 RRRSSSSSSSSSASRTSSSRSSSRSSSRSRRG----GGYYRSGRHARSRSRSWSRSRSRS 429
Query: 191 YSGSRSRSRSRRRSRSRSR---RSSRSRSRSISKS-RSRSRSRSKGRSRSRSKGRKSRSK 246
SRSRSR RR S SR R SRS +R R RSRSRS R R GR R
Sbjct: 430 RRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHH 489
Query: 247 SKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLP 306
S S+ +S S S SRSRS +RSRS S SP S+SRSRS+SRS SP P
Sbjct: 490 SSSRSRSS-WSLSPSRSRS-----LTRSRSHSPSP---------SQSRSRSRSRSQSPSP 534
Query: 307 VP 308
P
Sbjct: 535 SP 536
Score = 57.0 bits (136), Expect = 2e-08
Identities = 54/184 (29%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 189 RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSK 248
R +S SRSRS S S SRSR +RSRS S S S+SRSRSRS+ +S S S R+ ++
Sbjct: 487 RHHSSSRSRS-SWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPA 545
Query: 249 SKP--------------------------------KSDRGSHSHSRSRSKDEYEKSRSRS 276
+ P + + + ++ K EK +
Sbjct: 546 ASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQE 605
Query: 277 RSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRS 336
R +E+ + K R + + R + S P SR S SR +SRS
Sbjct: 606 HERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRS 665
Query: 337 RSRS 340
RSRS
Sbjct: 666 RSRS 669
Score = 56.6 bits (135), Expect = 3e-08
Identities = 57/207 (27%), Positives = 86/207 (41%), Gaps = 26/207 (12%)
Query: 156 YSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSR 215
Y +R+ + + R R + + R S+S S SRSRS RSRS S S+SR
Sbjct: 463 YGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSR 522
Query: 216 SRSISKSRSRSRSRSK------------GRSRSRSKGRKSRSKSKSKPK----------S 253
SRS S+S+S S S ++ G +++ + +KPK
Sbjct: 523 SRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRM 582
Query: 254 DRGSHSHSRSRSKDEYEKSRSRSRSRSPKENG----KGDIKSKSRSRSQSRSNSPLPVPP 309
+ + ++ K EK + R +E+ I+ K R R +
Sbjct: 583 QKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYS 642
Query: 310 SKARSVSPPPKRATSRSRSRSRSKSRS 336
++RS SP R S SR RSRS+SRS
Sbjct: 643 RQSRSPSPRYSREYSSSRRRSRSRSRS 669
Score = 52.0 bits (123), Expect = 8e-07
Identities = 66/221 (29%), Positives = 89/221 (40%), Gaps = 21/221 (9%)
Query: 139 ADAHKERTNEGVIEFRSYSDMKRAL--DKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRS 196
AD +K+ T G+ + D R L DK + I L E+K S RRS R
Sbjct: 219 ADLNKQATTYGMAD----GDFVRMLRKDKEEAEAIKHAKA-LEEEKAMYSGRRSRRQRRE 273
Query: 197 RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG-RKSRSKSKSKPKSDR 255
R R R S S R RS S S SRSRS+ R + + S
Sbjct: 274 FREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFG 333
Query: 256 GSHSHSRSRSKDEYEKSRSRSRSRSPKENG--KGDIKSKSRSRSQSRSNSPLPVPPSKAR 313
GS + + + + + +P + G + +R RS S S+S S +R
Sbjct: 334 GSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR 393
Query: 314 SVSPPPKRAT-----------SRSRSRSRSKSRSRSRSSSR 343
S S R+ +RSRSRS S+SRSRSR SR
Sbjct: 394 SSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSR 434
Score = 30.8 bits (68), Expect = 1.8
Identities = 47/233 (20%), Positives = 81/233 (34%), Gaps = 35/233 (15%)
Query: 69 HARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRC--SWQDL 126
H+ G RD YS GG RR+ R G R R + + SSR SW
Sbjct: 442 HSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLS 501
Query: 127 KDFMRQAGEVTYADAHKERTNEGVIEFRSYSDM------KRALDKLDGTEINGRNIRLIE 180
R +T + +H ++ RS S + L + + G ++ E
Sbjct: 502 PSRSRS---LTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTE 558
Query: 181 D---------KPRTSHR------------RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSI 219
KP+ + + R + + ++ + + R+ R++
Sbjct: 559 PAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAM 618
Query: 220 SKS---RSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEY 269
++ + R R + R R+SRS S + S SRSRS+ +
Sbjct: 619 ARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPH 671
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 89.7 bits (221), Expect = 3e-18
Identities = 75/189 (39%), Positives = 96/189 (50%), Gaps = 17/189 (8%)
Query: 126 LKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNI----RLIED 181
LK+ + E D ++ + + E D + LD +E N R
Sbjct: 145 LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRS 204
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSR-SKGRSRSR--- 237
K R+SH RS S S S S SR RSRSRSR SS S+SRS S SR RSRSR SK RS SR
Sbjct: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
Query: 238 ---SKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
S ++S S S S P+ +R SRSRS ++ + R+RSRSP+ + S
Sbjct: 265 GSSSPRKRSYSSSSSSPERNR---KRSRSRSSSSGDRKKRRTRSRSPERRHR---SSSGS 318
Query: 295 SRSQSRSNS 303
S S SRS+S
Sbjct: 319 SHSGSRSSS 327
Score = 86.3 bits (212), Expect = 4e-17
Identities = 64/145 (44%), Positives = 83/145 (57%), Gaps = 9/145 (6%)
Query: 196 SRSRSRRRSRSRSRRS-SRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSD 254
++ +S RRSRS+SR S SRS SRS S S SRSRSRS+ RS S S+ R SRS S+ + +S
Sbjct: 194 NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR-SRSSSRERSRS- 251
Query: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARS 314
RGS S S SRS R RS S S ++R RS+SRS+S + RS
Sbjct: 252 RGSKSRSSSRSHRGSSSPRKRSYSSSSSS------PERNRKRSRSRSSSSGDRKKRRTRS 305
Query: 315 VSPPPKRATSRSRSRSRSKSRSRSR 339
SP + +S S S S+S S+ +
Sbjct: 306 RSPERRHRSSSGSSHSGSRSSSKKK 330
Score = 72.4 bits (176), Expect = 6e-13
Identities = 78/249 (31%), Positives = 102/249 (40%), Gaps = 45/249 (18%)
Query: 119 SRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRS----YSDMKRALDKLDGTEINGR 174
S C+ + + + Y ER N IE Y + R K G +
Sbjct: 83 SECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPA 142
Query: 175 NI-RLIEDKPRTSHRRSYSGSRSRSR---------------SRRRSRSRSRRSSRSRSRS 218
+I + +EDK S+ + + S +S RS
Sbjct: 143 SILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRS 202
Query: 219 ISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR-SR 277
SKSRS S SRS RS S S SRS+S+S+ +S S S SRS S+ E+SRSR S+
Sbjct: 203 RSKSRS-SHSRSSSRSSSPSS---SRSRSRSRSRSSSSSQSRSRSSSR---ERSRSRGSK 255
Query: 278 SRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRS---RSKS 334
SRS + +G + RS S S S SP R SRSRS S R K
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSSSS--------------SPERNRKRSRSRSSSSGDRKKR 301
Query: 335 RSRSRSSSR 343
R+RSRS R
Sbjct: 302 RTRSRSPER 310
Score = 58.9 bits (141), Expect = 6e-09
Identities = 45/123 (36%), Positives = 60/123 (48%), Gaps = 11/123 (8%)
Query: 229 RSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSK-------DEYEKSRSRSRSRSP 281
R K + R ++ G S K +S+ SK DE + S+ +
Sbjct: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS 188
Query: 282 KENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
+E KS RSRS+SRS+ S +RS SP R+ SRSRSRS S S+SRSRSS
Sbjct: 189 EEEDSNKKKSNRRSRSKSRSSHSR----SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSS 244
Query: 342 SRD 344
SR+
Sbjct: 245 SRE 247
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/153 (35%), Positives = 69/153 (45%), Gaps = 14/153 (9%)
Query: 125 DLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPR 184
DL + A E D++K+++N +S S R+ + + R
Sbjct: 179 DLSKYNLDASEEE--DSNKKKSNRRS-RSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
Query: 185 TSHRRSYSGSRSRSRSR---RRSRSRSRRSSRS-RSRSISKS-------RSRSRSRSKGR 233
+S RS S SR RSRSR RS SRS R S S R RS S S R RSRSRS
Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSS 295
Query: 234 SRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSK 266
+ + +SRS + S SHS SRS SK
Sbjct: 296 GDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
Score = 42.7 bits (99), Expect = 5e-04
Identities = 47/191 (24%), Positives = 72/191 (37%), Gaps = 27/191 (14%)
Query: 37 YGFVEFEDSRDADDAVYELNGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRT 96
Y E ED DAD + Y L+ E + R + R +S S SSR
Sbjct: 167 YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRS- 225
Query: 97 SGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSY 156
R+ R + S S ++ R G + + + R + + RSY
Sbjct: 226 ----------RSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRK-RSY 274
Query: 157 SDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRS 216
S + ++ ++ R+ R S SG R + R+R RS R RSS S
Sbjct: 275 SSSSSSPER---------------NRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319
Query: 217 RSISKSRSRSR 227
S S+S S+ +
Sbjct: 320 HSGSRSSSKKK 330
Score = 42.4 bits (98), Expect = 6e-04
Identities = 33/63 (52%), Positives = 37/63 (58%), Gaps = 3/63 (4%)
Query: 188 RRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKS 247
+RSYS S S S R R RSRSR SS S R ++RSRS R + RS S S SRS S
Sbjct: 271 KRSYSSSSS-SPERNRKRSRSRSSS-SGDRKKRRTRSRSPER-RHRSSSGSSHSGSRSSS 327
Query: 248 KSK 250
K K
Sbjct: 328 KKK 330
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 88.6 bits (218), Expect = 7e-18
Identities = 65/169 (38%), Positives = 93/169 (55%), Gaps = 8/169 (4%)
Query: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRSR-RSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
DK +R S RSRS+ + S +SR R+S SRSR+ +S RS+ RSRSRS+
Sbjct: 1810 DKGEKEKKRD-SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSR 1868
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRS-Q 298
R+ S+S+SK + R R RS KSR R R RS + + ++++SR+ S +
Sbjct: 1869 RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR 1928
Query: 299 SRSNSPLPVPPSKA----RSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
SRS++P S++ RS S P R + RSR+ SR RSR+ SR
Sbjct: 1929 SRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR-RSRTPSR 1976
Score = 85.1 bits (209), Expect = 8e-17
Identities = 66/184 (35%), Positives = 96/184 (52%), Gaps = 7/184 (3%)
Query: 164 DKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSR 223
DK + + ++R + ++S +S + S SRSR R RS +S RS++RS S+SR
Sbjct: 1810 DKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT-SESRSRARKRSSKSKSHRSQTRSRSRSR 1868
Query: 224 SRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKE 283
R RS S+ RS+SR + S+ K K PK S R RS + R+RSR+P
Sbjct: 1869 RRRRS-SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 284 NGKGDIKS-KSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRS---RSRSKSRSRSR 339
+ S + RSRS R S P ++R+ S + + RSR+ RSR+ SR RSR
Sbjct: 1928 RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR-RSR 1986
Query: 340 SSSR 343
+ SR
Sbjct: 1987 TPSR 1990
Score = 80.1 bits (196), Expect = 3e-15
Identities = 76/207 (36%), Positives = 104/207 (50%), Gaps = 14/207 (6%)
Query: 147 NEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGS-RSRSRSRRRSR 205
++G E + S ++ + +E R R E + R R S S S RS++RSR RSR
Sbjct: 1810 DKGEKEKKRDSSLRSRSKRSKSSEHKSRK-RTSESRSRARKRSSKSKSHRSQTRSRSRSR 1868
Query: 206 SRSRRSSRSRS-----RSISK-SRSRS---RSRSKGRSRSRSKGRKSRSKSKSKPKS-DR 255
R RRSSRSRS RS+SK R RS RS+S+ R R RS R +R +++ ++ R
Sbjct: 1869 -RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 256 GSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSV 315
S SH+ SR + R RS S SP + + +SR+ S PS+ RS
Sbjct: 1928 RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR-RSR 1986
Query: 316 SPPPKRATSRSRSRSRSKSRSRSRSSS 342
+P + T R RSRS R RS S S
Sbjct: 1987 TPSRRSRTPSRRRRSRSVVRRRSFSIS 2013
Score = 78.2 bits (191), Expect = 1e-14
Identities = 68/168 (40%), Positives = 91/168 (54%), Gaps = 9/168 (5%)
Query: 180 EDKPRTSHRRSYSGSRSRS----RSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
+ + RTS RS + RS RS+ RSRSRSRR RS SRS SKSR R RS SK + +
Sbjct: 1835 KSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS-SRSRSKSRGR-RSVSKEKRK 1892
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295
K R + K K S R + R+RS+ +SRS + SR + G +S S S
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSIS 1952
Query: 296 RSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
S+ RS +P + +R P +R+ + SR RSR+ SR RSR+ SR
Sbjct: 1953 PSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSR-RSRTPSR 1997
Score = 75.9 bits (185), Expect = 5e-14
Identities = 65/171 (38%), Positives = 90/171 (52%), Gaps = 24/171 (14%)
Query: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRS-ISKSRSRSRSRSKGRSRSRSK 239
+K + + R + S RSRS+ +SS +SR S+SRSR+R RS S+SK
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-----SKSK 1855
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR-SRSRSPKENGKGDIKSKSRSRSQ 298
+S+++S+S+ + R S SRSRSK +S S+ R RSPK +SKSR R +
Sbjct: 1856 SHRSQTRSRSRSRRRRRS---SRSRSKSRGRRSVSKEKRKRSPKH------RSKSRERKR 1906
Query: 299 SRSNSPLPVPPSKARSVSP--------PPKRATSRSRSRSRSKSRSRSRSS 341
RS+S +ARS +P P +R SRS R RS S S SR S
Sbjct: 1907 KRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRS 1957
Score = 74.3 bits (181), Expect = 1e-13
Identities = 82/274 (29%), Positives = 127/274 (46%), Gaps = 16/274 (5%)
Query: 76 DRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGE 135
++D Y + S++ RDK + + L + S+ S + ++
Sbjct: 1786 EKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRS 1845
Query: 136 VTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSR 195
+ K +++ RS S +R + R++ + K HR S+
Sbjct: 1846 RARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHR-----SK 1900
Query: 196 SRSRSRRRSRSR-SRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSD 254
SR R R+RS SR +R++ R+RSR+ S+ RSRS + S+ R RSRS GR+ RS S S +
Sbjct: 1901 SRERKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSR-RRRSRSVGRR-RSFSISPSRRS 1957
Query: 255 RGSHSHSRS---RSKDEYEKSRSRSR-SRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPS 310
R SR+ RS+ +SR+ SR SR+P + + + RSRS R S + P
Sbjct: 1958 RTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRR-RSRSVVRRRS-FSISPV 2015
Query: 311 KARSVSPPPKRATSRSR-SRSRSKSRSRSRSSSR 343
+ R P +R SRS R RS+S R RS R
Sbjct: 2016 RLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Score = 62.0 bits (149), Expect = 7e-10
Identities = 51/157 (32%), Positives = 76/157 (48%), Gaps = 13/157 (8%)
Query: 195 RSRSRSRRRSRSRSRRSSRSRSRS-----ISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS 249
R RS + S R+S S S I + +SK ++++R KG K + + S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSK-KNKNRDKGEKEKKRDSS 1821
Query: 250 -KPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVP 308
+ +S R S +SR + +SR+R RS K + +S++RSRS+SR
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH-----RSQTRSRSRSRRRRRSSRS 1876
Query: 309 PSKARSVSPPPKRATSRS-RSRSRSKSRSRSRSSSRD 344
SK+R K RS + RS+S+ R R RSSSRD
Sbjct: 1877 RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD 1913
Score = 30.4 bits (67), Expect = 2.4
Identities = 36/103 (34%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 154 RSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSR---SRSRSRRRS------ 204
RS + +R+ + R R + RT RRS + SR SRS RRRS
Sbjct: 1956 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPV 2015
Query: 205 ---RSRS---RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR 241
RSR+ RR SRS R +SRS R RS R K +
Sbjct: 2016 RLRRSRTPLRRRFSRSPIRR-KRSRSSERGRSPKRLTDLDKAQ 2057
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 88.6 bits (218), Expect = 7e-18
Identities = 65/169 (38%), Positives = 93/169 (55%), Gaps = 8/169 (4%)
Query: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRSR-RSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
DK +R S RSRS+ + S +SR R+S SRSR+ +S RS+ RSRSRS+
Sbjct: 1810 DKGEKEKKRD-SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSR 1868
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRS-Q 298
R+ S+S+SK + R R RS KSR R R RS + + ++++SR+ S +
Sbjct: 1869 RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR 1928
Query: 299 SRSNSPLPVPPSKA----RSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
SRS++P S++ RS S P R + RSR+ SR RSR+ SR
Sbjct: 1929 SRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR-RSRTPSR 1976
Score = 85.1 bits (209), Expect = 8e-17
Identities = 66/184 (35%), Positives = 96/184 (52%), Gaps = 7/184 (3%)
Query: 164 DKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSR 223
DK + + ++R + ++S +S + S SRSR R RS +S RS++RS S+SR
Sbjct: 1810 DKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT-SESRSRARKRSSKSKSHRSQTRSRSRSR 1868
Query: 224 SRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKE 283
R RS S+ RS+SR + S+ K K PK S R RS + R+RSR+P
Sbjct: 1869 RRRRS-SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 284 NGKGDIKS-KSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRS---RSRSKSRSRSR 339
+ S + RSRS R S P ++R+ S + + RSR+ RSR+ SR RSR
Sbjct: 1928 RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR-RSR 1986
Query: 340 SSSR 343
+ SR
Sbjct: 1987 TPSR 1990
Score = 80.1 bits (196), Expect = 3e-15
Identities = 76/207 (36%), Positives = 104/207 (50%), Gaps = 14/207 (6%)
Query: 147 NEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGS-RSRSRSRRRSR 205
++G E + S ++ + +E R R E + R R S S S RS++RSR RSR
Sbjct: 1810 DKGEKEKKRDSSLRSRSKRSKSSEHKSRK-RTSESRSRARKRSSKSKSHRSQTRSRSRSR 1868
Query: 206 SRSRRSSRSRS-----RSISK-SRSRS---RSRSKGRSRSRSKGRKSRSKSKSKPKS-DR 255
R RRSSRSRS RS+SK R RS RS+S+ R R RS R +R +++ ++ R
Sbjct: 1869 -RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 256 GSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSV 315
S SH+ SR + R RS S SP + + +SR+ S PS+ RS
Sbjct: 1928 RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR-RSR 1986
Query: 316 SPPPKRATSRSRSRSRSKSRSRSRSSS 342
+P + T R RSRS R RS S S
Sbjct: 1987 TPSRRSRTPSRRRRSRSVVRRRSFSIS 2013
Score = 78.2 bits (191), Expect = 1e-14
Identities = 68/168 (40%), Positives = 91/168 (54%), Gaps = 9/168 (5%)
Query: 180 EDKPRTSHRRSYSGSRSRS----RSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
+ + RTS RS + RS RS+ RSRSRSRR RS SRS SKSR R RS SK + +
Sbjct: 1835 KSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS-SRSRSKSRGR-RSVSKEKRK 1892
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295
K R + K K S R + R+RS+ +SRS + SR + G +S S S
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSIS 1952
Query: 296 RSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
S+ RS +P + +R P +R+ + SR RSR+ SR RSR+ SR
Sbjct: 1953 PSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSR-RSRTPSR 1997
Score = 75.9 bits (185), Expect = 5e-14
Identities = 65/171 (38%), Positives = 90/171 (52%), Gaps = 24/171 (14%)
Query: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRS-ISKSRSRSRSRSKGRSRSRSK 239
+K + + R + S RSRS+ +SS +SR S+SRSR+R RS S+SK
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-----SKSK 1855
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR-SRSRSPKENGKGDIKSKSRSRSQ 298
+S+++S+S+ + R S SRSRSK +S S+ R RSPK +SKSR R +
Sbjct: 1856 SHRSQTRSRSRSRRRRRS---SRSRSKSRGRRSVSKEKRKRSPKH------RSKSRERKR 1906
Query: 299 SRSNSPLPVPPSKARSVSP--------PPKRATSRSRSRSRSKSRSRSRSS 341
RS+S +ARS +P P +R SRS R RS S S SR S
Sbjct: 1907 KRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRS 1957
Score = 74.3 bits (181), Expect = 1e-13
Identities = 82/274 (29%), Positives = 127/274 (46%), Gaps = 16/274 (5%)
Query: 76 DRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGE 135
++D Y + S++ RDK + + L + S+ S + ++
Sbjct: 1786 EKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRS 1845
Query: 136 VTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSR 195
+ K +++ RS S +R + R++ + K HR S+
Sbjct: 1846 RARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHR-----SK 1900
Query: 196 SRSRSRRRSRSR-SRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSD 254
SR R R+RS SR +R++ R+RSR+ S+ RSRS + S+ R RSRS GR+ RS S S +
Sbjct: 1901 SRERKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSR-RRRSRSVGRR-RSFSISPSRRS 1957
Query: 255 RGSHSHSRS---RSKDEYEKSRSRSR-SRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPS 310
R SR+ RS+ +SR+ SR SR+P + + + RSRS R S + P
Sbjct: 1958 RTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRR-RSRSVVRRRS-FSISPV 2015
Query: 311 KARSVSPPPKRATSRSR-SRSRSKSRSRSRSSSR 343
+ R P +R SRS R RS+S R RS R
Sbjct: 2016 RLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Score = 62.0 bits (149), Expect = 7e-10
Identities = 51/157 (32%), Positives = 76/157 (48%), Gaps = 13/157 (8%)
Query: 195 RSRSRSRRRSRSRSRRSSRSRSRS-----ISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS 249
R RS + S R+S S S I + +SK ++++R KG K + + S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSK-KNKNRDKGEKEKKRDSS 1821
Query: 250 -KPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVP 308
+ +S R S +SR + +SR+R RS K + +S++RSRS+SR
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH-----RSQTRSRSRSRRRRRSSRS 1876
Query: 309 PSKARSVSPPPKRATSRS-RSRSRSKSRSRSRSSSRD 344
SK+R K RS + RS+S+ R R RSSSRD
Sbjct: 1877 RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD 1913
Score = 30.4 bits (67), Expect = 2.4
Identities = 36/103 (34%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 154 RSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSR---SRSRSRRRS------ 204
RS + +R+ + R R + RT RRS + SR SRS RRRS
Sbjct: 1956 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPV 2015
Query: 205 ---RSRS---RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR 241
RSR+ RR SRS R +SRS R RS R K +
Sbjct: 2016 RLRRSRTPLRRRFSRSPIRR-KRSRSSERGRSPKRLTDLDKAQ 2057
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 88.2 bits (217), Expect = 1e-17
Identities = 74/212 (34%), Positives = 105/212 (49%), Gaps = 12/212 (5%)
Query: 139 ADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSR--- 195
+D + E + R + A + D E R+ R + R+ RR+ S SR
Sbjct: 212 SDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSR---SRSRSRRRRTPSSSRHRR 268
Query: 196 SRSRSRRR--SRSRSRRSSRSRSRSISKSRSRS-RSRSKGRSRSRSKGRKSRSKSKSKPK 252
SRSRSRRR S+SRSRR S+S R S SR R RSRS ++R + K K + +SK+ PK
Sbjct: 269 SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
Query: 253 SDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKA 312
S + SRS S+ E + RSRS +RSPK+ + + SRS S R K
Sbjct: 329 S-YSTARRSRSASR-ERRRRRSRSGTRSPKK-PRSPKRKLSRSPSPRRHKKEKKKDKDKE 385
Query: 313 RSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
RS + + + +S+ + K R R S +D
Sbjct: 386 RSRDERERSTSKKKKSKDKEKDRERKSESDKD 417
Score = 57.0 bits (136), Expect = 2e-08
Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Query: 180 EDKPRTSHRRSYSGSR-SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRS 238
E K + +SYS +R SRS SR R R RSR +RS + S R SRS S R +
Sbjct: 319 EKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK 378
Query: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR------SRSRSPKENGKGDIKSK 292
K K + +S+ + + S+ + KD KS S +R +E G K K
Sbjct: 379 KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEK 438
Query: 293 SRSRSQSRSNSP 304
+ + SP
Sbjct: 439 KEEKKPIETGSP 450
Score = 52.8 bits (125), Expect = 5e-07
Identities = 43/132 (32%), Positives = 60/132 (45%), Gaps = 23/132 (17%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRS---------------RS 226
K ++ RRS S SR R R R RS +RS + RS R +S+S S RS
Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387
Query: 227 RSRSKGRSRSRSKGRKSRSKSKS---KPKSDRGSHSHSRSRSKDE--YEKSRSRSRSRSP 281
R R RS SK +KS+ K K K +SD+ +R ++E Y+ + + + P
Sbjct: 388 RDE---RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKP 444
Query: 282 KENGKGDIKSKS 293
E G K S
Sbjct: 445 IETGSPKTKECS 456
Score = 49.7 bits (117), Expect = 4e-06
Identities = 38/122 (31%), Positives = 60/122 (49%), Gaps = 16/122 (13%)
Query: 223 RSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPK 282
+S + S+ + R + +S + +P HSRSRS+ ++ S SR R
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHR--- 267
Query: 283 ENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
+S+SRSR +S S S S+ RS SP +R+ SR R R RS+S S++R
Sbjct: 268 -------RSRSRSRRRSHSKSR-----SRRRSKSPRRRRSHSRERGR-RSRSTSKTRDKK 314
Query: 343 RD 344
++
Sbjct: 315 KE 316
Score = 28.5 bits (62), Expect = 9.2
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 9/93 (9%)
Query: 256 GSHSHSRSRSKDEYEKSRSRSRSRSPKENGKG------DIKSKSRSRSQSRSNSPLPVPP 309
G++ +S+S + D+ K S + PK N +KS + S+ + +
Sbjct: 174 GANLNSQSLAADQLLKLMS---TVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQ 230
Query: 310 SKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
S + P K+ R SRSRS+SR R SS
Sbjct: 231 SLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSS 263
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 87.8 bits (216), Expect = 1e-17
Identities = 69/172 (40%), Positives = 92/172 (53%), Gaps = 8/172 (4%)
Query: 143 KERTNEGVIEFRSYSDMKRALDK---LDGTEINGRNIRLIEDKP---RTSHRRSYSGSRS 196
+++ +EG E K LD+ D +++ N+ E++ + S+RRS S SRS
Sbjct: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
Query: 197 -RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS-KPKSD 254
SRS RS S S SRSRSRS S S S+SRSRS R RSRS+G KSRS S+S + S
Sbjct: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
Query: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLP 306
S+S S S E + RSRSRS S + K +S+S N+ P
Sbjct: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPESQVIGENTKQP 320
Score = 85.5 bits (210), Expect = 6e-17
Identities = 69/174 (39%), Positives = 89/174 (51%), Gaps = 14/174 (8%)
Query: 126 LKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNI----RLIED 181
LK+ + E D ++ + + E D + LD +E N R
Sbjct: 145 LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRS 204
Query: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSR-SKGRSRSR--- 237
K R+SH RS S S S S SR RSRSRSR SS S+SRS S SR RSRSR SK RS SR
Sbjct: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
Query: 238 ---SKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGD 288
S ++S S S S P+ +R SRSRS ++ + R+RSRSP+ G+
Sbjct: 265 GSSSPRKRSYSSSSSSPERNR---KRSRSRSSSSGDRKKRRTRSRSPESQVIGE 315
Score = 79.3 bits (194), Expect = 5e-15
Identities = 71/230 (30%), Positives = 97/230 (42%), Gaps = 13/230 (5%)
Query: 119 SRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRS----YSDMKRALDKLDGTEINGR 174
S C+ + + + Y ER N IE Y + R K G +
Sbjct: 83 SECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPA 142
Query: 175 NI-RLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR 233
+I + +EDK S+ + + ++ S ++ K
Sbjct: 143 SILKEVEDKESEGEEEDEDEDLSKYKL---DEDEDEDDADLSKYNLDASEEEDSNKKKSN 199
Query: 234 SRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293
RSRSK R S S+S S+ S S S SRSRS+ S+SRSRS S + + KS+S
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSS-SSSQSRSRSSSRERSRSRGSKSRS 258
Query: 294 RSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRS---RSKSRSRSRS 340
SRS S+SP S + S SP R SRSRS S R K R+RSRS
Sbjct: 259 SSRSHRGSSSPRKRSYSSSSS-SPERNRKRSRSRSSSSGDRKKRRTRSRS 307
Score = 58.9 bits (141), Expect = 6e-09
Identities = 45/123 (36%), Positives = 60/123 (48%), Gaps = 11/123 (8%)
Query: 229 RSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSK-------DEYEKSRSRSRSRSP 281
R K + R ++ G S K +S+ SK DE + S+ +
Sbjct: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS 188
Query: 282 KENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
+E KS RSRS+SRS+ S +RS SP R+ SRSRSRS S S+SRSRSS
Sbjct: 189 EEEDSNKKKSNRRSRSKSRSSH----SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSS 244
Query: 342 SRD 344
SR+
Sbjct: 245 SRE 247
Score = 31.2 bits (69), Expect = 1.4
Identities = 53/192 (27%), Positives = 68/192 (35%), Gaps = 51/192 (26%)
Query: 37 YGFVEFEDSRDADDAVYELNGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRT 96
Y E ED DAD + Y L+ E + R + R +S S S SS R+
Sbjct: 167 YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSS-SRSSSPSSSRS 225
Query: 97 SGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSY 156
R + SR S + + + +ER+ + RS
Sbjct: 226 RSRSR-----------------SRSS---------SSSQSRSRSSSRERSRSRGSKSRSS 259
Query: 157 SDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRS 216
S R PR +RSYS S S S R R RSRSR SS S
Sbjct: 260 SRSHRG-----------------SSSPR---KRSYSSS-SSSPERNRKRSRSRSSS---S 295
Query: 217 RSISKSRSRSRS 228
K R+RSRS
Sbjct: 296 GDRKKRRTRSRS 307
>gi|148612890 serine-arginine repressor protein [Homo sapiens]
Length = 261
Score = 87.0 bits (214), Expect = 2e-17
Identities = 71/209 (33%), Positives = 103/209 (49%), Gaps = 23/209 (11%)
Query: 151 IEFRSYSDMKRALDKLDGTEINGRNIRL------------IEDKPR-----TSHRRSYSG 193
++F D + AL L+ + GR I + ++ K R + HRRS S
Sbjct: 56 VQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSP 115
Query: 194 SRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSK-PK 252
S+ R+RSR S R+RR RS S+ +SR R S S+ +SRS+S R+S S +S+ P+
Sbjct: 116 SQRRTRSRSSSWGRNRR----RSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPR 171
Query: 253 SDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSR-SQSRSNSPLPVPPSK 311
+ GS SRS+S + KS +S+S SP++ KS+S R S S + SP P
Sbjct: 172 RNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGY 231
Query: 312 ARSVSPPPKRATSRSRSRSRSKSRSRSRS 340
S + S RS SRS+S S
Sbjct: 232 TNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
Score = 83.6 bits (205), Expect = 2e-16
Identities = 80/290 (27%), Positives = 128/290 (44%), Gaps = 60/290 (20%)
Query: 4 VYIGRLSYNVREKDIQRFFSGYGRLLEVDLK--------NGYGFVEFEDSRDADDAVYEL 55
++I ++ R +D++R F YG +++V + G+ +V+FED RDA+DA+Y L
Sbjct: 12 LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
Query: 56 NGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVE 115
N K +CG ++ ++ A+G R+ + G + + R P R
Sbjct: 72 NRKWVCGRQIEIQFAQGDRK-----TPGQMKSKERHPCSPSDHRRSRSPSQR-------R 119
Query: 116 NLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFR----SYSDMKRALDKLDGTEI 171
S SW R ++ + E R SYS K L
Sbjct: 120 TRSRSSSW-----------------GRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRST 162
Query: 172 NGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRS-RSRS 230
+ R R + RR++ GSR RSRS +S + RS+SI KS+S S + ++
Sbjct: 163 SARQSR--------TPRRNF-GSRGRSRS---------KSLQKRSKSIGKSQSSSPQKQT 204
Query: 231 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280
++SRS GR S S ++S KS +G + ++ RS SRSRS
Sbjct: 205 SSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
Score = 45.4 bits (106), Expect = 7e-05
Identities = 43/112 (38%), Positives = 56/112 (50%), Gaps = 22/112 (19%)
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295
S S R+SRS S+ + +S S +R RS D ++SR R S S +SKSRS
Sbjct: 105 SPSDHRRSRSPSQRRTRSRSSSWGRNRRRS-DSLKESRHRRFSYS---------QSKSRS 154
Query: 296 RSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRS-----RSKSRSRSRSSS 342
+S LP + AR P + SR RSRS RSKS +S+SSS
Sbjct: 155 KS-------LPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSS 199
Score = 33.1 bits (74), Expect = 0.37
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 27/103 (26%)
Query: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR 300
RK+ + KSK + H RSRS + R+RSRS S N + +S S +SR
Sbjct: 90 RKTPGQMKSKERHPCSPSDHRRSRSPSQ---RRTRSRSSSWGRN-----RRRSDSLKESR 141
Query: 301 SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
R S S+S+SRSKS R +S+R
Sbjct: 142 H-------------------RRFSYSQSKSRSKSLPRRSTSAR 165
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 86.3 bits (212), Expect = 4e-17
Identities = 65/148 (43%), Positives = 81/148 (54%), Gaps = 23/148 (15%)
Query: 181 DKPRTSHRRSYSGS----RSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRS 236
D+PR S +G R++ R+RRR R S SRSRS SKSR RS SRS RS S
Sbjct: 700 DRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS-S 758
Query: 237 RSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS- 295
+S G SRS+S+S S S+SRSR SRSRSRSRS + + +S+S+S
Sbjct: 759 KSSGSYSRSRSRSC------SRSYSRSR-------SRSRSRSRSSRSRSRSQSRSRSKSY 805
Query: 296 ----RSQSRSNSPLPVPPSKARSVSPPP 319
R +SRS SP P + S S PP
Sbjct: 806 SPGRRRRSRSRSPTPPSSAGLGSNSAPP 833
Score = 81.6 bits (200), Expect = 9e-16
Identities = 58/132 (43%), Positives = 72/132 (54%), Gaps = 22/132 (16%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
++K + RS S S+SR RS RS SRS +SS S SRS S+S SRS SRS+ RSRSRS+
Sbjct: 729 QEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR 788
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299
+SRS+S+S RSRSK R RSRSRSP +
Sbjct: 789 SSRSRSRSQS------------RSRSKSYSPGRRRRSRSRSPTPPSSAGL---------- 826
Query: 300 RSNSPLPVPPSK 311
SNS P+P S+
Sbjct: 827 GSNSAPPIPDSR 838
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/126 (42%), Positives = 68/126 (53%), Gaps = 34/126 (26%)
Query: 223 RSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSR-SRSKDEYEKSRSRSRSRSP 281
R++ R+R + R+ G SRS+S+SK + S S+SR S+S Y +SRSRS SRS
Sbjct: 718 RAKMRARRRKGQEKRNSG-PSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRS- 775
Query: 282 KENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKS------- 334
S+SRSRS+SRS S R+ SRS+SRSRSKS
Sbjct: 776 --------YSRSRSRSRSRSRS----------------SRSRSRSQSRSRSKSYSPGRRR 811
Query: 335 RSRSRS 340
RSRSRS
Sbjct: 812 RSRSRS 817
Score = 63.9 bits (154), Expect = 2e-10
Identities = 49/120 (40%), Positives = 62/120 (51%), Gaps = 12/120 (10%)
Query: 143 KERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRR 202
+ R +G + S R+ K G + N R + S RS S SRS SRSR
Sbjct: 722 RARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRS 781
Query: 203 RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS-KPKSDRGSHSHS 261
RSRSRSR SRSRSRS+S+ RS+S S GR+ RS+S+S P S G S+S
Sbjct: 782 RSRSRSR-----------SSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNS 830
Score = 55.1 bits (131), Expect = 9e-08
Identities = 41/94 (43%), Positives = 53/94 (56%), Gaps = 12/94 (12%)
Query: 259 SHSRSRSKDEYE----------KSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVP 308
SH R R+ + +E K R+R R K N G +S+SRS+S+ RS+S
Sbjct: 698 SHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNS-GPSRSRSRSKSRGRSSSRSNSR 756
Query: 309 PSKAR-SVSPPPKRATSRSRSRSRSKSRSRSRSS 341
SK+ S S R+ SRS SRSRS+SRSRSRSS
Sbjct: 757 SSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSS 790
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 84.7 bits (208), Expect = 1e-16
Identities = 94/332 (28%), Positives = 135/332 (40%), Gaps = 101/332 (30%)
Query: 107 RTEYRLIVENLSSRCSWQD-LKDFMRQAGEVTY---ADAHKERTNEGVIEFRSYSDMKRA 162
RT Y V NL+S+ + D L +F +Q GEV + A + T +EF + + RA
Sbjct: 182 RTVY---VGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRA 238
Query: 163 LDKLDGTEINGRNIRL---------------------IED----------------KPRT 185
L +G R +++ +E+ +P +
Sbjct: 239 L-AFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPES 297
Query: 186 SHRRSYSGSRSRSRSRRRSRSRSR-RSSRSRSRSISKSRSRSRSRSKGRSRSRSKG-RKS 243
G RSRS +R +SRS S+ S R RS+S +SRS +RSRS+ + R RSK K
Sbjct: 298 GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 357
Query: 244 RSKSKSKPKSDRGSHSHSRSRSKD--------------EYEKSRSRSRSR-SPKENGKGD 288
RSKS+ + KS S SHSR + KD + EK R R + R KE GK
Sbjct: 358 RSKSRERRKSR--SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Query: 289 IKSKSRSRSQSRS-----------------------------------NSPLPVPPSKAR 313
+ K R + + + + + K +
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475
Query: 314 SVSPPPK--RATSRSRSRSRSKSRSRSRSSSR 343
PP+ A+ RSRS SR + R RSRSSSR
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 507
Score = 80.1 bits (196), Expect = 3e-15
Identities = 64/202 (31%), Positives = 93/202 (46%), Gaps = 48/202 (23%)
Query: 182 KPRTSHR-RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSK--------- 231
+ ++ HR RS++ SRSR + RRRS+S ++ S+SR R S+SRS SR + K
Sbjct: 328 RSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK 387
Query: 232 ------------------------GRSRSRSKGR-KSRSKSKSKPKSDRGSHSHSRSRSK 266
G+++ R K R K R K K K + H + R K
Sbjct: 388 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 447
Query: 267 D-----EYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKR 321
+ + EK R + RS+ E K D KS++ RS + S ++RS S +R
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR--------RSRSSSRERRR 499
Query: 322 ATSRSRSRSRSKSRSRSRSSSR 343
SRS SRS S++ R SSR
Sbjct: 500 RRSRSSSRSPRTSKTIKRKSSR 521
Score = 66.2 bits (160), Expect = 4e-11
Identities = 70/272 (25%), Positives = 111/272 (40%), Gaps = 40/272 (14%)
Query: 74 RRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLS---SRCSWQDLKDFM 130
RR R + SRS S ++ R K R++ R ++ S SR +D ++ +
Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 384
Query: 131 RQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRS 190
++ V D KER E +R +K G ++K R R
Sbjct: 385 KEKERVKEKDREKERERE----------KEREKEKERG-----------KNKDRDKEREK 423
Query: 191 YSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSK 250
R + + + R R R + + R + K + + + R K RS+ + RK KS++
Sbjct: 424 ---DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 480
Query: 251 PKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPS 310
P+S S RSRS E+ R RSRS S +S S++ R +S P P S
Sbjct: 481 PRSYNASR---RSRSSSR-ERRRRRSRSSS---------RSPRTSKTIKRKSSRSPSPRS 527
Query: 311 KARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
+ + K S R R +S S +SS+
Sbjct: 528 RNKKDKKREKERDHISERRERERSTSMRKSSN 559
Score = 60.1 bits (144), Expect = 3e-09
Identities = 56/173 (32%), Positives = 76/173 (43%), Gaps = 19/173 (10%)
Query: 127 KDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTS 186
KD R+ + D KE+ E E D + +D+ + +DK +
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE-----------KRKKDKKSRT 479
Query: 187 HRRSYSGSR-SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRS 245
RSY+ SR SRS SR R R RSR SSRS S + R SRS S RSR+K K R
Sbjct: 480 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP---RSRNKKDKKRE 536
Query: 246 KSK----SKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
K + + + +R + S +D EK S S KE+ K S S+
Sbjct: 537 KERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 589
Score = 48.9 bits (115), Expect = 7e-06
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 23/172 (13%)
Query: 140 DAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHR-RSYSGSRSRS 198
D KER + E D KR DK T N + R+S R R SRS S
Sbjct: 454 DKEKEREKDRSKEI----DEKRKKDKKSRTPPRSYNA---SRRSRSSSRERRRRRSRSSS 506
Query: 199 RSRRRSRSRSRRSSRS---RSRS------------ISKSRSRSRSRSKGRSRSRSKGRKS 243
RS R S++ R+SSRS RSR+ IS+ R R RS S +S + G++
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 566
Query: 244 RSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295
K+ + K + S SK+ +K R+ + NG + ++ S
Sbjct: 567 LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLS 618
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 84.7 bits (208), Expect = 1e-16
Identities = 94/332 (28%), Positives = 135/332 (40%), Gaps = 101/332 (30%)
Query: 107 RTEYRLIVENLSSRCSWQD-LKDFMRQAGEVTY---ADAHKERTNEGVIEFRSYSDMKRA 162
RT Y V NL+S+ + D L +F +Q GEV + A + T +EF + + RA
Sbjct: 66 RTVY---VGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRA 122
Query: 163 LDKLDGTEINGRNIRL---------------------IED----------------KPRT 185
L +G R +++ +E+ +P +
Sbjct: 123 L-AFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPES 181
Query: 186 SHRRSYSGSRSRSRSRRRSRSRSR-RSSRSRSRSISKSRSRSRSRSKGRSRSRSKG-RKS 243
G RSRS +R +SRS S+ S R RS+S +SRS +RSRS+ + R RSK K
Sbjct: 182 GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 241
Query: 244 RSKSKSKPKSDRGSHSHSRSRSKD--------------EYEKSRSRSRSR-SPKENGKGD 288
RSKS+ + KS S SHSR + KD + EK R R + R KE GK
Sbjct: 242 RSKSRERRKSR--SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 289 IKSKSRSRSQSRS-----------------------------------NSPLPVPPSKAR 313
+ K R + + + + + K +
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359
Query: 314 SVSPPPK--RATSRSRSRSRSKSRSRSRSSSR 343
PP+ A+ RSRS SR + R RSRSSSR
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 391
Score = 80.1 bits (196), Expect = 3e-15
Identities = 64/202 (31%), Positives = 93/202 (46%), Gaps = 48/202 (23%)
Query: 182 KPRTSHR-RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSK--------- 231
+ ++ HR RS++ SRSR + RRRS+S ++ S+SR R S+SRS SR + K
Sbjct: 212 RSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK 271
Query: 232 ------------------------GRSRSRSKGR-KSRSKSKSKPKSDRGSHSHSRSRSK 266
G+++ R K R K R K K K + H + R K
Sbjct: 272 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 331
Query: 267 D-----EYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKR 321
+ + EK R + RS+ E K D KS++ RS + S ++RS S +R
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR--------RSRSSSRERRR 383
Query: 322 ATSRSRSRSRSKSRSRSRSSSR 343
SRS SRS S++ R SSR
Sbjct: 384 RRSRSSSRSPRTSKTIKRKSSR 405
Score = 66.2 bits (160), Expect = 4e-11
Identities = 70/272 (25%), Positives = 111/272 (40%), Gaps = 40/272 (14%)
Query: 74 RRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLS---SRCSWQDLKDFM 130
RR R + SRS S ++ R K R++ R ++ S SR +D ++ +
Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 268
Query: 131 RQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRS 190
++ V D KER E +R +K G ++K R R
Sbjct: 269 KEKERVKEKDREKERERE----------KEREKEKERG-----------KNKDRDKEREK 307
Query: 191 YSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSK 250
R + + + R R R + + R + K + + + R K RS+ + RK KS++
Sbjct: 308 ---DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 364
Query: 251 PKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPS 310
P+S S RSRS E+ R RSRS S +S S++ R +S P P S
Sbjct: 365 PRSYNASR---RSRSSSR-ERRRRRSRSSS---------RSPRTSKTIKRKSSRSPSPRS 411
Query: 311 KARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
+ + K S R R +S S +SS+
Sbjct: 412 RNKKDKKREKERDHISERRERERSTSMRKSSN 443
Score = 60.1 bits (144), Expect = 3e-09
Identities = 56/173 (32%), Positives = 76/173 (43%), Gaps = 19/173 (10%)
Query: 127 KDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTS 186
KD R+ + D KE+ E E D + +D+ + +DK +
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE-----------KRKKDKKSRT 363
Query: 187 HRRSYSGSR-SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRS 245
RSY+ SR SRS SR R R RSR SSRS S + R SRS S RSR+K K R
Sbjct: 364 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP---RSRNKKDKKRE 420
Query: 246 KSK----SKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
K + + + +R + S +D EK S S KE+ K S S+
Sbjct: 421 KERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 473
Score = 48.9 bits (115), Expect = 7e-06
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 23/172 (13%)
Query: 140 DAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHR-RSYSGSRSRS 198
D KER + E D KR DK T N + R+S R R SRS S
Sbjct: 338 DKEKEREKDRSKEI----DEKRKKDKKSRTPPRSYNA---SRRSRSSSRERRRRRSRSSS 390
Query: 199 RSRRRSRSRSRRSSRS---RSRS------------ISKSRSRSRSRSKGRSRSRSKGRKS 243
RS R S++ R+SSRS RSR+ IS+ R R RS S +S + G++
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 450
Query: 244 RSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295
K+ + K + S SK+ +K R+ + NG + ++ S
Sbjct: 451 LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLS 502
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 84.3 bits (207), Expect = 1e-16
Identities = 52/120 (43%), Positives = 70/120 (58%), Gaps = 5/120 (4%)
Query: 184 RTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKS 243
+ S R SGSRSRSRS RS+ RSRSR + R RSRSR K RSRSR + R
Sbjct: 10 KRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLR 69
Query: 244 RSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNS 303
RS+S+ + + S RSRS+D +SRSRSR R + + G+ K+ +RS+S+ +
Sbjct: 70 RSRSRERDR----SRERRRSRSRDR-RRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKT 124
Score = 77.8 bits (190), Expect = 1e-14
Identities = 56/150 (37%), Positives = 78/150 (52%), Gaps = 20/150 (13%)
Query: 195 RSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSD 254
R R+RS SR R SRSRSRS S RS+ + RSR R + R+ RS+S+ K +
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDR-RRERSRSRDKRR-- 59
Query: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARS 314
SRSR + +SRSR R RS + +S+SR R +SRS S RS
Sbjct: 60 ------SRSRDRKRLRRSRSRERDRSRERR-----RSRSRDRRRSRSRS------RGRRS 102
Query: 315 VSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
S P + ++ +RSRSK ++ SS++
Sbjct: 103 RSSSPGNKSKKTENRSRSKEKTDGGESSKE 132
Score = 76.6 bits (187), Expect = 3e-14
Identities = 48/109 (44%), Positives = 61/109 (55%), Gaps = 17/109 (15%)
Query: 184 RTSHRRSYSGSRSRSRSRRRSRSRSR-----RSSRSRSRSISKSRSRSRSRSKGRSRSRS 238
R S R R RSRSR + RSRSR R SRSR R S+ R RSRSR + RSRSRS
Sbjct: 38 RRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRS 97
Query: 239 KGRKSRS------------KSKSKPKSDRGSHSHSRSRSKDEYEKSRSR 275
+GR+SRS +S+SK K+D G S + + KD+ E + +
Sbjct: 98 RGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEK 146
Score = 73.6 bits (179), Expect = 2e-13
Identities = 44/110 (40%), Positives = 62/110 (56%), Gaps = 4/110 (3%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
+D+ S R RSRSR +RRSRSR R+ R RSRS + RSR R RS+ R R RS+
Sbjct: 36 DDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLR-RSRSRERDRSRERRRSRSRDRRRSR 94
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSK---DEYEKSRSRSRSRSPKENGK 286
R +S+S ++ + +RSRSK D E S+ + + + KE+ K
Sbjct: 95 SRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK 144
Score = 55.1 bits (131), Expect = 9e-08
Identities = 42/138 (30%), Positives = 61/138 (44%), Gaps = 12/138 (8%)
Query: 158 DMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSR-RSSRSRS 216
+ R+ DK + + +R + R RS RSRSR RRRSRSRSR R SRS S
Sbjct: 50 ERSRSRDKRRSRSRDRKRLRRSRSRERD---RSRERRRSRSRDRRRSRSRSRGRRSRSSS 106
Query: 217 RSISKSRSRSRSRSK--------GRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDE 268
++ +RSRSK + + + K K K K D+ + K+
Sbjct: 107 PGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKER 166
Query: 269 YEKSRSRSRSRSPKENGK 286
EK R R ++ + G+
Sbjct: 167 VEKWREEQRKKAMENIGE 184
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 83.2 bits (204), Expect = 3e-16
Identities = 51/130 (39%), Positives = 75/130 (57%), Gaps = 7/130 (5%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
E++ + R RSRSRSR SR+ RR SRSR S+SR R RSRS+ R RSRS
Sbjct: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
Query: 240 GR-----KSRSKSKSKPKS-DRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293
R +SRS+ + + KS DR S+ H RS+S+D + +S+ + + ++ K +KS S
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKH-RSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395
Query: 294 RSRSQSRSNS 303
R + +N+
Sbjct: 396 REKQSEDTNT 405
Score = 75.9 bits (185), Expect = 5e-14
Identities = 62/191 (32%), Positives = 86/191 (45%), Gaps = 27/191 (14%)
Query: 158 DMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSR---RRSRSRSRRSSRS 214
D + +K + E R E++ R R + R+R R +RSRSRSR SSR+
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRT 303
Query: 215 RSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRS 274
R S+SR RSRS+ R RSRS+ R R S SH RS K +SRS
Sbjct: 304 SDRRCSRSRDHKRSRSRERRRSRSRDR-------------RRSRSHDRSERK---HRSRS 347
Query: 275 RSRSRSPKENGKG-DIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK 333
R R RS + K +SKSR R Q R + + K+++ +S SR +
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRDREQDRKS-------KEKEKRGSDDKKSSVKSGSREKQS 400
Query: 334 SRSRSRSSSRD 344
+ + S D
Sbjct: 401 EDTNTESKESD 411
Score = 74.3 bits (181), Expect = 1e-13
Identities = 63/176 (35%), Positives = 81/176 (46%), Gaps = 14/176 (7%)
Query: 140 DAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRR-SYSGSRSRS 198
+ +ER E R + +R ++ E R+ RTS RR S S RS
Sbjct: 258 EKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 199 RSRR--RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKS-------KS 249
RSR RSRSR RR SRS RS K RSRSR R + +SR R K K RSKS KS
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR-KSYKHRSKSRDREQDRKS 376
Query: 250 KPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS---RSRSQSRSN 302
K K RGS S EK + + S + + K ++ S +S ++SN
Sbjct: 377 KEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
Score = 66.2 bits (160), Expect = 4e-11
Identities = 46/165 (27%), Positives = 74/165 (44%), Gaps = 17/165 (10%)
Query: 179 IEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRS 238
+E+ +R+ R + + R R R R + + R + + R+R
Sbjct: 227 VEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQ 298
+ R+ RS+S+S+ S SRSR ++++SRSR R RS +S+ R RS+
Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSR---DHKRSRSRERRRS---------RSRDRRRSR 334
Query: 299 SRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
S S K RS S +R+ SR R + +S+SR R R
Sbjct: 335 SHDRS-----ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDR 374
Score = 57.0 bits (136), Expect = 2e-08
Identities = 39/124 (31%), Positives = 56/124 (45%), Gaps = 17/124 (13%)
Query: 221 KSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280
K + R R+ R K ++ R + + + + +R R R ++E EK R+R R R
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 281 PKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRS 340
+ S+SRSR SR++ R S SRSR R RS+SR R RS
Sbjct: 291 KR--------SRSRSRHSSRTSD---------RRCSRSRDHKRSRSRERRRSRSRDRRRS 333
Query: 341 SSRD 344
S D
Sbjct: 334 RSHD 337
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 83.2 bits (204), Expect = 3e-16
Identities = 51/130 (39%), Positives = 75/130 (57%), Gaps = 7/130 (5%)
Query: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
E++ + R RSRSRSR SR+ RR SRSR S+SR R RSRS+ R RSRS
Sbjct: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
Query: 240 GR-----KSRSKSKSKPKS-DRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293
R +SRS+ + + KS DR S+ H RS+S+D + +S+ + + ++ K +KS S
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKH-RSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395
Query: 294 RSRSQSRSNS 303
R + +N+
Sbjct: 396 REKQSEDTNT 405
Score = 75.9 bits (185), Expect = 5e-14
Identities = 62/191 (32%), Positives = 86/191 (45%), Gaps = 27/191 (14%)
Query: 158 DMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSR---RRSRSRSRRSSRS 214
D + +K + E R E++ R R + R+R R +RSRSRSR SSR+
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRT 303
Query: 215 RSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRS 274
R S+SR RSRS+ R RSRS+ R R S SH RS K +SRS
Sbjct: 304 SDRRCSRSRDHKRSRSRERRRSRSRDR-------------RRSRSHDRSERK---HRSRS 347
Query: 275 RSRSRSPKENGKG-DIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK 333
R R RS + K +SKSR R Q R + + K+++ +S SR +
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRDREQDRKS-------KEKEKRGSDDKKSSVKSGSREKQS 400
Query: 334 SRSRSRSSSRD 344
+ + S D
Sbjct: 401 EDTNTESKESD 411
Score = 74.3 bits (181), Expect = 1e-13
Identities = 63/176 (35%), Positives = 81/176 (46%), Gaps = 14/176 (7%)
Query: 140 DAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRR-SYSGSRSRS 198
+ +ER E R + +R ++ E R+ RTS RR S S RS
Sbjct: 258 EKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 199 RSRR--RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKS-------KS 249
RSR RSRSR RR SRS RS K RSRSR R + +SR R K K RSKS KS
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR-KSYKHRSKSRDREQDRKS 376
Query: 250 KPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKS---RSRSQSRSN 302
K K RGS S EK + + S + + K ++ S +S ++SN
Sbjct: 377 KEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
Score = 66.2 bits (160), Expect = 4e-11
Identities = 46/165 (27%), Positives = 74/165 (44%), Gaps = 17/165 (10%)
Query: 179 IEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRS 238
+E+ +R+ R + + R R R R + + R + + R+R
Sbjct: 227 VEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQ 298
+ R+ RS+S+S+ S SRSR ++++SRSR R RS +S+ R RS+
Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSR---DHKRSRSRERRRS---------RSRDRRRSR 334
Query: 299 SRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
S S K RS S +R+ SR R + +S+SR R R
Sbjct: 335 SHDRS-----ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDR 374
Score = 57.0 bits (136), Expect = 2e-08
Identities = 39/124 (31%), Positives = 56/124 (45%), Gaps = 17/124 (13%)
Query: 221 KSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280
K + R R+ R K ++ R + + + + +R R R ++E EK R+R R R
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 281 PKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRS 340
+ S+SRSR SR++ R S SRSR R RS+SR R RS
Sbjct: 291 KR--------SRSRSRHSSRTSD---------RRCSRSRDHKRSRSRERRRSRSRDRRRS 333
Query: 341 SSRD 344
S D
Sbjct: 334 RSHD 337
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 82.4 bits (202), Expect = 5e-16
Identities = 70/183 (38%), Positives = 97/183 (53%), Gaps = 16/183 (8%)
Query: 170 EINGRNIRL-IEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSR------SRSISKS 222
E+ + +R+ I+ K + + R +R RR R++ S S+S S S
Sbjct: 1256 EMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPS 1315
Query: 223 RSRSRSRSKGRSRSRSKG-RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSP 281
RSRS+S +K R R+RS SRS+S+S S R S S+SRSRS+ Y + R+RSRS S
Sbjct: 1316 RSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYR-SRSYSRSRSRGWYSRGRTRSRSSSY 1374
Query: 282 KENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRS-RSKSRSRSRS 340
+ S+SRSRS S P S++RS + + SRSRSRS RS S R RS
Sbjct: 1375 RSYKSHRTSSRSRSRSSSYD------PHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRS 1428
Query: 341 SSR 343
+R
Sbjct: 1429 YNR 1431
Score = 79.3 bits (194), Expect = 5e-15
Identities = 61/162 (37%), Positives = 81/162 (50%), Gaps = 9/162 (5%)
Query: 184 RTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRS---RSKGRSRSRSKG 240
+T R S SRS SRSR +S ++SR +RS S S S+SRSRS + RS+ SRSRS+G
Sbjct: 1301 QTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRG 1360
Query: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR 300
SR +++S+ S R SH S +SRSRS S P + SRS+SR
Sbjct: 1361 WYSRGRTRSRSSSYRSYKSHRTS------SRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR 1414
Query: 301 SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
S S + RS + + S +S S RS S
Sbjct: 1415 SRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPS 1456
Score = 63.2 bits (152), Expect = 3e-10
Identities = 52/111 (46%), Positives = 58/111 (52%), Gaps = 14/111 (12%)
Query: 189 RSYSGSRSR---SRSRRRSRSRS-------RRSSRSRSRSIS---KSRSRSRSRSKGRSR 235
RSYS SRSR SR R RSRS S R SSRSRSRS S SRSRS + SR
Sbjct: 1351 RSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSR 1410
Query: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGK 286
SRS+ R RS S + +S RS D E RS S RSP E+ +
Sbjct: 1411 SRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDS-ESDRSYSHHRSPSESSR 1460
Score = 62.0 bits (149), Expect = 7e-10
Identities = 59/166 (35%), Positives = 75/166 (45%), Gaps = 35/166 (21%)
Query: 179 IEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRS 238
IE K + R R +R R R++ SS S+SRS S+ RS
Sbjct: 1264 IEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRS---- 1319
Query: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQ 298
KS +KS+ + +S SHS SRSRS +SRS SRSRS +G SR R++
Sbjct: 1320 ---KSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRS-----RGWY---SRGRTR 1368
Query: 299 SRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
SRS+S RS R+ SRSRSRSSS D
Sbjct: 1369 SRSSS--------------------YRSYKSHRTSSRSRSRSSSYD 1394
Score = 58.9 bits (141), Expect = 6e-09
Identities = 57/162 (35%), Positives = 76/162 (46%), Gaps = 26/162 (16%)
Query: 181 DKPRTSHRRSYSGSRSRS-RSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
+K S + +YS RS S RSRSRS SRSRS S+S +RSRS + SRSRS
Sbjct: 668 EKNSESDQSTYSKYSDRSSESSPRSRSRS-----SRSRSYSRSYTRSRSLASSHSRSRSP 722
Query: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299
S SHSR++ D + SRS S + ++G+ ++K R RS
Sbjct: 723 ----------------SSRSHSRNKYSDHSQCSRSSSYTSISSDDGR---RAKRRLRSSG 763
Query: 300 RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
+ NS S + + K R RS S + S SRSS
Sbjct: 764 KKNSVSHKKHSSSSEKTLHSKYVKGRDRS-SCVRKYSESRSS 804
Score = 55.8 bits (133), Expect = 5e-08
Identities = 61/251 (24%), Positives = 100/251 (39%), Gaps = 32/251 (12%)
Query: 92 SSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVI 151
S + S DK P + + +LS R + ++ HK+R E +
Sbjct: 379 SGEKWSKGDKLSDPCSSRWD--ERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKV 436
Query: 152 EF-----------RSYSDMKRAL---DKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSR 197
+ R KR + ++ ++ + R ++ D+ R+S S S S
Sbjct: 437 KHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSS 496
Query: 198 SRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGS 257
R +S + S SR +S+S S+S S+G SRSR+ KS S S+S+ K
Sbjct: 497 KRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRT-ASKSSSHSRSRSK----- 550
Query: 258 HSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSV-- 315
SRS SK + K S+S ++ + + R+ N + V P A ++
Sbjct: 551 ---SRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPV 607
Query: 316 -----SPPPKR 321
SPPP R
Sbjct: 608 IPLSDSPPPSR 618
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/151 (27%), Positives = 72/151 (47%), Gaps = 9/151 (5%)
Query: 191 YSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSK 250
+SG + R ++ + + + + R +++ R S+S R+ +S S +
Sbjct: 423 HSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKS-SCDR 481
Query: 251 PKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPS 310
+S R S S SK ++ KS +S S + + +SKS S+S SR +S
Sbjct: 482 ERSSRSSSLSSHHSSKRDWSKSDKDVQS-SLTHSSRDSYRSKSHSQSYSRGSS------- 533
Query: 311 KARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
++R+ S + SRS+SRS SKS R R+S
Sbjct: 534 RSRTASKSSSHSRSRSKSRSSSKSGHRKRAS 564
Score = 51.6 bits (122), Expect = 1e-06
Identities = 51/170 (30%), Positives = 77/170 (45%), Gaps = 12/170 (7%)
Query: 177 RLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSR-------SR 229
R E PR+ R S S RS SRS RSRS + SRSRS S S+S SR++ SR
Sbjct: 684 RSSESSPRSRSRSSRS--RSYSRSYTRSRSLASSHSRSRSPS-SRSHSRNKYSDHSQCSR 740
Query: 230 SKG-RSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGD 288
S S S GR+++ + +S K + SH S S+ + R RS +
Sbjct: 741 SSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSE 800
Query: 289 IKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRS 338
+S S S +S ++ + +R T + ++R + +S+S
Sbjct: 801 SRSSLDYSSDSEQSSVQATQSAQEKEKQGQMER-THNKQEKNRGEEKSKS 849
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/152 (28%), Positives = 67/152 (44%), Gaps = 3/152 (1%)
Query: 195 RSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSD 254
RSRS S S + S + + + + KG+ + + K K + SD
Sbjct: 405 RSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSD 464
Query: 255 RGSHSHSRSRSKDEYEKSRS-RSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKA- 312
S S R K ++ RS RS S S + K D + S ++S SK+
Sbjct: 465 IESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSH 524
Query: 313 -RSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
+S S R+ + S+S S S+SRS+SRSSS+
Sbjct: 525 SQSYSRGSSRSRTASKSSSHSRSRSKSRSSSK 556
Score = 48.9 bits (115), Expect = 7e-06
Identities = 42/94 (44%), Positives = 51/94 (54%), Gaps = 13/94 (13%)
Query: 182 KPRTSHRRSYSGSRSRSRSRRRS-------RSRSRRSSRSRSRSISKSRSRSRSRSKGRS 234
+ R+S RSY R+ SRSR RS RSRS SRS S+SRS+ RS
Sbjct: 1368 RSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQ---RSDSYH 1424
Query: 235 RSRSKGRKSRS--KSKSKPKSDRGSHSHSRSRSK 266
R RS R+SRS S +SDR S+SH RS S+
Sbjct: 1425 RGRSYNRRSRSCRSYGSDSESDR-SYSHHRSPSE 1457
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 14/150 (9%)
Query: 187 HRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSI--------SKSRSRSRSRSKGRSRS-R 237
H++ + + + + + + RR +++ R I SKS +R S R RS R
Sbjct: 427 HKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSR 486
Query: 238 SKGRKSRSKSKSK-PKSDRGSHSHSRSRSKDEYE-KSRSRSRSRSPKENGKGDIKSKSRS 295
S S SK KSD+ S S+D Y KS S+S SR + + SKS S
Sbjct: 487 SSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRG---SSRSRTASKSSS 543
Query: 296 RSQSRSNSPLPVPPSKARSVSPPPKRATSR 325
S+SRS S + S P++ S+
Sbjct: 544 HSRSRSKSRSSSKSGHRKRASKSPRKTASQ 573
Score = 46.2 bits (108), Expect = 4e-05
Identities = 40/144 (27%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
Query: 205 RSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS--KPKSDRGSHSHSR 262
R + ++ + I + S + + G S S K K+ +S SDR S S R
Sbjct: 632 RIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPR 691
Query: 263 SRSKDE----YEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPP 318
SRS+ Y +S +RSRS + + S+S SR++ +S S S
Sbjct: 692 SRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDD 751
Query: 319 PKRATSRSRSRSRSKSRSRSRSSS 342
+RA R RS + S S + SS
Sbjct: 752 GRRAKRRLRSSGKKNSVSHKKHSS 775
Score = 46.2 bits (108), Expect = 4e-05
Identities = 67/284 (23%), Positives = 107/284 (37%), Gaps = 22/284 (7%)
Query: 56 NGKELCGERVIVEHARGPRRDRDGYS-YGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIV 114
N KE + + D+ YS Y RS SR S R + T R +
Sbjct: 654 NIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLA 713
Query: 115 ENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKL--DGTEIN 172
+ S S R Y+D H + + S D +RA +L G + +
Sbjct: 714 SSHSRSRSPSS-----RSHSRNKYSD-HSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNS 767
Query: 173 GRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSR--RSSRSRSRSISKSRSRSRSRS 230
+ + +T H + G S R+ S SRS SS S S+ ++S
Sbjct: 768 VSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEK 827
Query: 231 KGR-SRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDI 289
+G+ R+ +K K+R + KSK + + HS+ R+ E R+ S+ ++N G
Sbjct: 828 QGQMERTHNKQEKNRGEEKSKSERE---CPHSKKRTLKENLSDHLRNGSKPKRKNYAG-- 882
Query: 290 KSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK 333
S+ S SNS V + P + + S S S+
Sbjct: 883 -----SKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESE 921
Score = 43.9 bits (102), Expect = 2e-04
Identities = 58/209 (27%), Positives = 85/209 (40%), Gaps = 62/209 (29%)
Query: 186 SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSR-SRSKGRSRSRSKGRK-- 242
SH +SYS SRSR+ +S S SR SRS+SRS SKS R R S+S ++ S+ K
Sbjct: 523 SHSQSYSRGSSRSRTASKSSSHSR--SRSKSRSSSKSGHRKRASKSPRKTASQLSENKPV 580
Query: 243 --------------------------------SRSKSKSKPKSDRGSHSHSRSR------ 264
S S+ KP S+ R +
Sbjct: 581 KTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKT 640
Query: 265 ----------SKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARS 314
S +++ S S ++N + D + S+ +S +SP S++RS
Sbjct: 641 THLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPR----SRSRS 696
Query: 315 VSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
R+ S SRS +RS+S + S S SR
Sbjct: 697 -----SRSRSYSRSYTRSRSLASSHSRSR 720
Score = 42.0 bits (97), Expect = 8e-04
Identities = 42/156 (26%), Positives = 59/156 (37%), Gaps = 15/156 (9%)
Query: 204 SRSRSRRSSRSRSRS-ISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSR 262
S S S SS S S S + RSR R + RSK R+ + S +P++ +
Sbjct: 200 SSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGH 259
Query: 263 SRSKDEYEK-SRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPL-------------PVP 308
S D EK S S R +I +R R + P+ P+
Sbjct: 260 SERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIV 319
Query: 309 PSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
+ SVS ++ R R + RSRS S S D
Sbjct: 320 SDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDD 355
Score = 38.9 bits (89), Expect = 0.007
Identities = 50/190 (26%), Positives = 72/190 (37%), Gaps = 12/190 (6%)
Query: 157 SDMKRALDKLDGTEINGRNIRLIEDKPRT-SHRRSYSGSRSRSRSRRRSRSRSRRSSRSR 215
SD K ++ K G +I GR PR+ S S S + + + R+ R
Sbjct: 320 SDQKPSVSK-SGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPP 378
Query: 216 SRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR 275
S + R RS ++SRS S + SD + HS K R
Sbjct: 379 SGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKK--------R 430
Query: 276 SRSRSPKENGKGDIKSKSRSRSQSRSNSPL-PVPPSKARSVSPPPKRATSRSRSRSRSKS 334
+ + K KG + R Q++ L P ++S + K + R RS SRS S
Sbjct: 431 RKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERS-SRSSS 489
Query: 335 RSRSRSSSRD 344
S SS RD
Sbjct: 490 LSSHHSSKRD 499
Score = 35.0 bits (79), Expect = 0.098
Identities = 45/136 (33%), Positives = 62/136 (45%), Gaps = 19/136 (13%)
Query: 136 VTYADAH-KERTNEGVIEFRSYSDMK-RALDKLDGTEINGRNIRLIEDKPRTSHRRSYSG 193
V+Y+ + + R++ RSYS + R T + R + +S RS S
Sbjct: 1332 VSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSS 1391
Query: 194 S---RSRSRS--------RRRSRSRSRRS-SRSRSRSISKSRSRSRSRSKGRSRSRSKGR 241
S SRSRS R RSRSRS+RS S R RS ++ RSRS S S+
Sbjct: 1392 SYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNR-----RSRSCRSYGSDSESD 1446
Query: 242 KSRSKSKSKPKSDRGS 257
+S S +S +S R S
Sbjct: 1447 RSYSHHRSPSESSRYS 1462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,922,012
Number of Sequences: 37866
Number of extensions: 629939
Number of successful extensions: 24143
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 627
Number of HSP's successfully gapped in prelim test: 663
Number of HSP's that attempted gapping in prelim test: 5740
Number of HSP's gapped (non-prelim): 5842
length of query: 344
length of database: 18,247,518
effective HSP length: 103
effective length of query: 241
effective length of database: 14,347,320
effective search space: 3457704120
effective search space used: 3457704120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.