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Search of human proteins with 198442834
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|198442834 coiled-coil domain containing 152 [Homo sapiens]
(254 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|198442834 coiled-coil domain containing 152 [Homo sapiens] 490 e-139
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 60 2e-09
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 57 1e-08
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 54 1e-07
gi|4758650 kinesin family member 5C [Homo sapiens] 54 1e-07
gi|55770834 centromere protein F [Homo sapiens] 54 1e-07
gi|45439327 periplakin [Homo sapiens] 54 1e-07
gi|71061468 centromere protein E [Homo sapiens] 54 2e-07
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 53 2e-07
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 53 2e-07
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 53 3e-07
gi|32698688 citron [Homo sapiens] 53 3e-07
gi|9910266 kinesin family member 15 [Homo sapiens] 53 3e-07
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 52 4e-07
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 52 4e-07
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 52 4e-07
gi|38348729 hypothetical protein LOC203238 [Homo sapiens] 52 4e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 52 5e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 52 5e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 52 5e-07
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 52 5e-07
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 52 5e-07
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] 52 5e-07
gi|50083279 centrosome protein 4 [Homo sapiens] 51 9e-07
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 51 9e-07
gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens] 51 1e-06
gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens] 51 1e-06
gi|30794488 kinesin family member 27 [Homo sapiens] 50 1e-06
gi|4758648 kinesin family member 5B [Homo sapiens] 50 2e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens] 50 2e-06
>gi|198442834 coiled-coil domain containing 152 [Homo sapiens]
Length = 254
Score = 490 bits (1262), Expect = e-139
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MDQSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEV 60
MDQSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEV
Sbjct: 1 MDQSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEV 60
Query: 61 SIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVS 120
SIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVS
Sbjct: 61 SIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVS 120
Query: 121 EMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEI 180
EMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEI
Sbjct: 121 EMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEI 180
Query: 181 IKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQR 240
IKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQR
Sbjct: 181 IKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQR 240
Query: 241 LSVGKDSHLKRRRF 254
LSVGKDSHLKRRRF
Sbjct: 241 LSVGKDSHLKRRRF 254
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 60.1 bits (144), Expect = 2e-09
Identities = 54/210 (25%), Positives = 101/210 (48%), Gaps = 30/210 (14%)
Query: 33 ETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQ--------Q 84
E N K L+ +LEKSN ++++ K EE +N K + Q I+ + Q
Sbjct: 1550 ENNDKIQRLNEELEKSNECAEMLKQKV----EELTRQNNETKLMMQRIQAESENIVLEKQ 1605
Query: 85 NLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKV 144
++ E LKI AD K++L+S + + + E+ ++++I L +D+ +
Sbjct: 1606 TIQQRCEALKIQADGFKDQLRSTNEH--------LHKQTKTEQDFQRKIKCLEEDLAKSQ 1657
Query: 145 ELNEEKHKE------LIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKS 198
L E ++ +I+ + E+ LNA+L + ++EK+ K+QL+ A++ + +
Sbjct: 1658 NLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQ-QAQVQELNNRL 1716
Query: 199 KSYQDS---TVLPQSIYRRKLQHFQEEKNK 225
K QD + + + RK+ FQEE K
Sbjct: 1717 KKVQDELHLKTIEEQMTHRKMVLFQEESGK 1746
Score = 40.4 bits (93), Expect = 0.002
Identities = 53/269 (19%), Positives = 118/269 (43%), Gaps = 49/269 (18%)
Query: 10 KKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATL 69
+K + + KL S++E+ + E + + ++ +L K V +A E ++++ +
Sbjct: 1126 QKATVLENSKLTGKISELERMVAELKKQKSRVEEELPK------VREAAENELRKQQRNV 1179
Query: 70 HNI----IKGLQQTIEYQQNLK--------GENE-----QLKISADLIKEKLKSHEQEYK 112
+I I+ + +Y++ L+ E E QL I A+ + ++ + ++
Sbjct: 1180 EDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFR 1239
Query: 113 NNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVEL---------NEEKHKELIEKKEMEIS 163
N + + + E+ K++ L Q+K +L NEE+ +LI++ E +++
Sbjct: 1240 NQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLA 1299
Query: 164 ELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQ-------------TKSKSYQDSTVLPQS 210
Q KEKQ K++LE K+ +Q T++ S + T L Q
Sbjct: 1300 FQKQVAEKQLKEKQ----KIELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQE 1355
Query: 211 IYRRKLQHFQEEKNKEIAILRNTIRDLEQ 239
++K + +++ ++ A R +D+ +
Sbjct: 1356 HDKQKAEELKQQVDELTAANRKAEQDMRE 1384
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 57.4 bits (137), Expect = 1e-08
Identities = 51/207 (24%), Positives = 95/207 (45%), Gaps = 12/207 (5%)
Query: 53 KVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGE-NEQLKISADLIKEKLKSHEQEY 111
++ + KE S + L + Q+T E ++ LK E +EQ+K +E+ S +QE
Sbjct: 400 ELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQEL 459
Query: 112 KNNIAKLVSEMKIKEEG--------YKKEISKLYQDMQRKVELNEEKHKELIEKKEMEIS 163
++V MK E ++KE+++ Q++ +K++ E + +E + K +E S
Sbjct: 460 SRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQM-KVALEKS 518
Query: 164 ELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEK 223
+ SQEKE+Q + +LE K + T+S++ YR ++ +
Sbjct: 519 QSEYLKISQEKEQQESLALEELELQKKA--ILTESENKLRDLQQEAETYRTRILELESSL 576
Query: 224 NKEIAILRNTIRDLEQRLSVGKDSHLK 250
K + +N +DL L K+ H K
Sbjct: 577 EKSLQENKNQSKDLAVHLEAEKNKHNK 603
Score = 47.4 bits (111), Expect = 1e-05
Identities = 50/267 (18%), Positives = 124/267 (46%), Gaps = 26/267 (9%)
Query: 10 KKISSVNLDKLINDFSQIE--KKMVETNGKNNILDIQLEKSNC-------LLKVMQAKEV 60
K++ V +++L + + +++ ++M N +L+ E+ + LL M+A+
Sbjct: 1867 KEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHN 1926
Query: 61 SIKEECATLHNIIKGL-QQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLV 119
++ + A + L ++ + Q++L+ ++ + +++K K ++QE + I +
Sbjct: 1927 DLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILK---KEYDQEREEKIKQEQ 1983
Query: 120 SEMKIKEEGYKKEISKLY--QDMQRKVELN----------EEKHKELIEKKEMEISELNA 167
++++K K++ + + Q Q++ EL +E EL+E + E ++L
Sbjct: 1984 EDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLK 2043
Query: 168 KLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEI 227
K+ ++ + + + + DA+ + K + Q Q Y++KL+ + N +
Sbjct: 2044 KIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNV 2103
Query: 228 AILRNTIRDLEQRLSVGKDSHLKRRRF 254
I+ + L Q+ ++ DS LK + F
Sbjct: 2104 TIMELQTQ-LAQKTTLISDSKLKEQEF 2129
Score = 45.8 bits (107), Expect = 4e-05
Identities = 50/239 (20%), Positives = 110/239 (46%), Gaps = 32/239 (13%)
Query: 29 KKMVETNGKNNILDIQLEKSN----CLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQ 84
K+ E + + N+L +L++ N CL M+ + ++++ + L +K I
Sbjct: 1472 KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARI---M 1528
Query: 85 NLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKV 144
L+ Q I + + E LK++ Q+ +LV +++ +E +++ +++ + ++ +
Sbjct: 1529 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKIL 1588
Query: 145 ELNEEKH--KELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLA---------- 192
L + + K +E K+ E+ +N ++S+E+E + +L+ E AKLA
Sbjct: 1589 TLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKI 1648
Query: 193 ---------RVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLS 242
+++ K + Y+ T S KLQ E+ +E+ IL ++ +E S
Sbjct: 1649 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQ----EREREVHILEEKLKSVESSQS 1703
Score = 45.4 bits (106), Expect = 5e-05
Identities = 44/217 (20%), Positives = 98/217 (45%), Gaps = 27/217 (12%)
Query: 37 KNNILDIQLEKSNCLLKVMQAKEVSIKEECATL--HNI-IKGLQQTIE------------ 81
+ +LD++ E+ L K + E K+ C L H I ++ L Q +E
Sbjct: 825 QQKLLDLETERI-LLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKS 883
Query: 82 ----YQQNLKGENEQLKISADLIKEK---LKSHEQEYKNNIAKLVSEMKIKEEGY---KK 131
Y+ L+ N++ + + ++ EK + + K I L ++ KE+ +
Sbjct: 884 LTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNE 943
Query: 132 EISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAK- 190
E +++ ++K+E ++K KE+ E + ++ + AKL+ + + E+ + + +F+AK
Sbjct: 944 EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKM 1003
Query: 191 LARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEI 227
L Q S D+ ++ + +++ E +E+
Sbjct: 1004 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRREL 1040
Score = 43.9 bits (102), Expect = 1e-04
Identities = 55/265 (20%), Positives = 114/265 (43%), Gaps = 27/265 (10%)
Query: 1 MDQSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGK-NNILDIQLEKSNC-LLKVMQAK 58
M +SSE + K+ ++ +L ++ KK+ + + + LEKS LK+ Q K
Sbjct: 470 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEK 529
Query: 59 EVSIKEECATLHNIIKGLQQTIEYQQN----LKGENEQLKISADLIKEKLKSHEQEYKNN 114
E ++E L + + + +N L+ E E + ++ L+ QE KN
Sbjct: 530 E---QQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 586
Query: 115 IAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKE----------LIEKKEMEISE 164
L ++ ++ + KEI+ + + + K EL KH++ L ++ + E+ +
Sbjct: 587 SKDLAVHLEAEKNKHNKEITVMVE--KHKTELESLKHQQDALWTEKLQVLKQQYQTEMEK 644
Query: 165 LNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKN 224
L K E+EK+ + ++ F A + + K+ D +L + ++
Sbjct: 645 LREKC---EQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARH 701
Query: 225 K---EIAILRNTIRDLEQRLSVGKD 246
K E+++L++ ++Q L D
Sbjct: 702 KLEEELSVLKDQTDKMKQELEAKMD 726
Score = 42.4 bits (98), Expect = 4e-04
Identities = 53/248 (21%), Positives = 108/248 (43%), Gaps = 32/248 (12%)
Query: 1 MDQSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEV 60
M++ E C ++ ++ DK I + IE+ +T LEK L V Q +
Sbjct: 642 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKT----------LEK----LDVKQTELE 687
Query: 61 SIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVS 120
S+ E L + ++ + L+ E LK D +K++L++ E KN+ + V
Sbjct: 688 SLSSE----------LSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVD 737
Query: 121 EMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEI 180
+ + E + K +D ++EL ++ + +++ + + L A ++ E E Q
Sbjct: 738 SIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQAS 797
Query: 181 IKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEK---NKEIAILRNTIRDL 237
KL + F + + ++K+Y++ Q +KL + E+ K++A + +D+
Sbjct: 798 AKLDV-FQSYQSATHEQTKAYEEQLAQLQ----QKLLDLETERILLTKQVAEVEAQKKDV 852
Query: 238 EQRLSVGK 245
L K
Sbjct: 853 CTELDAHK 860
Score = 41.6 bits (96), Expect = 7e-04
Identities = 60/306 (19%), Positives = 126/306 (41%), Gaps = 56/306 (18%)
Query: 2 DQSSEGCMKKISSVNLDKLINDFSQIEKKMVET-----NGKNNILDIQLEKSNCLLKVMQ 56
D + E K V + +I + +KK +E + K + + I E+ K +
Sbjct: 894 DGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQE 953
Query: 57 AKEVSIKEECATLHNIIKG--LQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNN 114
K +K++ + +K L Q + ++ L+ +L K+ Q
Sbjct: 954 KKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAG 1013
Query: 115 IAKLVSEMKIKE--------EGYKKEISKLYQDMQRKVELNEEKHKEL----IEKKEMEI 162
I+ VS ++ + E +++E++ + ++K+ E+ +E+ +++KE E+
Sbjct: 1014 ISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEV 1073
Query: 163 SELNAK--LRSQEKEKQNEII---------------KLQLEFDAK------LARVQTK-- 197
+EL K L EKE+ N+ I +LQ + K LA+ +TK
Sbjct: 1074 AELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK 1133
Query: 198 ----------SKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDS 247
+KS +++T L + + K+ EE ++++ L + ++ ++ K S
Sbjct: 1134 AHLEKLEVDLNKSLKENTFLQEQLVELKM--LAEEDKRKVSELTSKLKTTDEEFQSLKSS 1191
Query: 248 HLKRRR 253
H K +
Sbjct: 1192 HEKSNK 1197
Score = 40.4 bits (93), Expect = 0.002
Identities = 52/242 (21%), Positives = 109/242 (45%), Gaps = 41/242 (16%)
Query: 38 NNILDIQLEKSNCLL--------KVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGE 89
N +++I K+N +L + + KE + + C T+ + L+Q E Q L
Sbjct: 1233 NELINISSSKTNAILSRISHCQHRTTKVKEALLIKTC-TVSELEAQLRQLTEEQNTLNIS 1291
Query: 90 NEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKI--KEEGYKKEISKLYQDM--QRKVE 145
+Q + + ++KS K +I LV+E + KE G +++ + + Q K E
Sbjct: 1292 FQQATHQLEEKENQIKS----MKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1347
Query: 146 LNEEKH-----KELIEKKEMEISELNAKLRSQE---------KEKQNEIIKLQLEFDAKL 191
L+E + KE +++K++EIS L+ +L EK+ I L+ ++D +
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEK 1407
Query: 192 ARV--QTKSKSYQDSTVLPQSI--------YRRKLQHFQEEKNKEIAILRNTIRDLEQRL 241
+ Q + S++ T+ + I + K ++++ +NT+++L+ +L
Sbjct: 1408 CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQL 1467
Query: 242 SV 243
+
Sbjct: 1468 EL 1469
Score = 39.3 bits (90), Expect = 0.003
Identities = 57/281 (20%), Positives = 123/281 (43%), Gaps = 50/281 (17%)
Query: 1 MDQSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNN-------ILDIQLEKSNCLLK 53
MD +E + S+N ++LI ++E+ + GK + +L + +K +L
Sbjct: 120 MDSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILS 179
Query: 54 VMQAKEV----SIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKI---SADLIKEKLKS 106
Q K + ++EE K LQ+ E+ +L+ +++ + + L+K++L++
Sbjct: 180 QSQDKSLRRIAELREELQMDQQAKKHLQE--EFDASLEEKDQYISVLQTQVSLLKQRLRN 237
Query: 107 HEQEYKNNIAKLVSEMKIKEEGYKKEIS---------------KLYQDMQRKVELNE--- 148
++ K + +++ + E + KE + K + +Q++V+ E
Sbjct: 238 GPMNV--DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLL 295
Query: 149 -------EKHKE----LIEKKEMEISELNAKLRSQEKEKQNEII-KLQLEFDAKLARVQT 196
+ HKE L +KE +L+ +L+ EK K + K +L + A+
Sbjct: 296 KRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLI 355
Query: 197 KSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDL 237
+ V+ ++ +R++ E K +EIA LR+ I+ +
Sbjct: 356 EQLEQDKGMVIAET--KRQMHETLEMKEEEIAQLRSRIKQM 394
Score = 35.4 bits (80), Expect = 0.048
Identities = 30/145 (20%), Positives = 66/145 (45%), Gaps = 24/145 (16%)
Query: 15 VNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIK 74
+ + + IN ++E +++E++ E++N LLK + K+ +K I+
Sbjct: 2014 MTIKETINKAQEVEAELLESHQ---------EETNQLLKKIAEKDDDLKRTAKRYEEILD 2064
Query: 75 GLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIA------------KLVSEM 122
++ E ++ QL+ ++KL+ E +N+ L+S+
Sbjct: 2065 AREE--EMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDS 2122
Query: 123 KIKEEGYKKEISKLYQDMQRKVELN 147
K+KE+ ++++I L +D +K E N
Sbjct: 2123 KLKEQEFREQIHNL-EDRLKKYEKN 2146
Score = 30.0 bits (66), Expect = 2.0
Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 36/136 (26%)
Query: 112 KNNIAKLVSEMKIKEEGYKKEISKL---YQDMQRKVELNEEKHKELIEKKEMEISELNAK 168
K + + + M+ Y+ + S+L YQ +QR+ + + + +K I+EL +
Sbjct: 136 KEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREE 195
Query: 169 LRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIA 228
L+ ++ K++ LQ EFDA L EEK++ I+
Sbjct: 196 LQMDQQAKKH----LQEEFDASL-----------------------------EEKDQYIS 222
Query: 229 ILRNTIRDLEQRLSVG 244
+L+ + L+QRL G
Sbjct: 223 VLQTQVSLLKQRLRNG 238
Score = 29.6 bits (65), Expect = 2.7
Identities = 47/242 (19%), Positives = 105/242 (43%), Gaps = 21/242 (8%)
Query: 25 SQIEKKMVETNGKNNILDIQLE-----KSNCLLKVMQAKEVSI---KEECATLHNIIKGL 76
S++ K+ E + +IL+ +L+ +S L+ AK V+ +EE + + K
Sbjct: 1675 SELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTY 1734
Query: 77 QQTIEY-QQNLKGENEQLKISADLIKEKLKSHEQ---EYKNNIAKLVSEMKIKEEGYKKE 132
++ I Q+NL + + L+ +E + SH + +Y+ + KL + K+ +
Sbjct: 1735 EEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL-EHAEAKQHEDQSM 1793
Query: 133 ISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLA 192
I L ++++ K N++ + + E E + N + + + +++ K E +
Sbjct: 1794 IGHLQEELEEK---NKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQ 1850
Query: 193 RVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRD-----LEQRLSVGKDS 247
++ K K V + ++R +++ + K A+ + R+ LE+ S
Sbjct: 1851 ILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKS 1910
Query: 248 HL 249
HL
Sbjct: 1911 HL 1912
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 54.3 bits (129), Expect = 1e-07
Identities = 53/253 (20%), Positives = 109/253 (43%), Gaps = 35/253 (13%)
Query: 20 LINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQT 79
L ND + ++ ++ + +N I EK N L + + ++ E T + K ++
Sbjct: 529 LENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAES 588
Query: 80 IEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQD 139
+ Q L+ N L+ L++ E+E+ N + L SE + + G S++ D
Sbjct: 589 SKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHG-----SEIIND 643
Query: 140 MQRKV---ELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKL------------- 183
+Q ++ E + + K L+ K E+E +L + EKEK N I +
Sbjct: 644 LQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQ 703
Query: 184 -QLEFDAKLARVQTKSKSYQ-------------DSTVLPQSIYRRKLQHFQEEKNKEIAI 229
+ E A AR+ K+K Y+ + +L + ++K+++ E K ++
Sbjct: 704 EEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSL 763
Query: 230 LRNTIRDLEQRLS 242
L ++ +Q+++
Sbjct: 764 LDCDLKQSQQKIN 776
Score = 43.9 bits (102), Expect = 1e-04
Identities = 47/246 (19%), Positives = 108/246 (43%), Gaps = 33/246 (13%)
Query: 15 VNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIK 74
+NL+K +++ K+ + +G+ L QLE + + + +KEEC + K
Sbjct: 839 MNLEK---QNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGK 895
Query: 75 GLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEIS 134
LQQ +Q L+ E + L ++ K S + +A+ ++E +
Sbjct: 896 ELQQK---KQELQDERDSLAAQLEITLTKADSEQ------LARSIAEEQ----------- 935
Query: 135 KLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQN------EIIKLQLEFD 188
Y D++++ + E + KE++ + + E++E +A + S E+ + + + E +
Sbjct: 936 --YSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELN 993
Query: 189 AKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRN--TIRDLEQRLSVGKD 246
KL VQ + +D + +I + + E+ + + I + ++ + G D
Sbjct: 994 NKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGND 1053
Query: 247 SHLKRR 252
+ ++R+
Sbjct: 1054 TDVRRK 1059
Score = 37.7 bits (86), Expect = 0.010
Identities = 45/193 (23%), Positives = 82/193 (42%), Gaps = 23/193 (11%)
Query: 64 EECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMK 123
EE + + L++ + + K E EQ S + EK + E E + + K V
Sbjct: 440 EESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT-AKELEEEITLRKSVESAL 498
Query: 124 IKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEII-- 181
+ E K + + QRK + +K + L E +++ L +L +K QN I
Sbjct: 499 RQLEREKALLQHKNAEYQRKADHEADKKRNL----ENDVNSLKDQLEDLKKRNQNSQIST 554
Query: 182 ----KLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDL 237
+LQ + D A ++T+S + +L+ Q E +K+I L + RDL
Sbjct: 555 EKVNQLQRQLDETNALLRTESDT------------AARLRKTQAESSKQIQQLESNNRDL 602
Query: 238 EQRLSVGKDSHLK 250
+ + + + + LK
Sbjct: 603 QDKNCLLETAKLK 615
Score = 35.4 bits (80), Expect = 0.048
Identities = 44/156 (28%), Positives = 76/156 (48%), Gaps = 24/156 (15%)
Query: 45 LEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIK--- 101
LE++N L A + KEE L+N +K +Q+ + LK E +ISA IK
Sbjct: 971 LEETNRTLTSDVANLANEKEE---LNNKLKDVQEQLS---RLKDE----EISAAAIKAQF 1020
Query: 102 EKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEME 161
EK E+ K ++E+ ++E K+ D++RK + N + H EL ++E +
Sbjct: 1021 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDT---DVRRKEKENRKLHMELKSERE-K 1076
Query: 162 ISELNAKLRSQEKEKQNEI-------IKLQLEFDAK 190
+++ K + + E Q +I I+LQ+ D+K
Sbjct: 1077 LTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSK 1112
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 54.3 bits (129), Expect = 1e-07
Identities = 59/225 (26%), Positives = 109/225 (48%), Gaps = 18/225 (8%)
Query: 39 NILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISAD 98
N + + LE + K KE KE+ TL N+I+ L+ + +N + E +ISA
Sbjct: 329 NTVSVNLELTAEEWKKKYEKE---KEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAK 385
Query: 99 LIKEKLKSHEQEYKNNIAKLVSEMKIKE-EGYKKEISKLYQDMQRK-VELNEEKH-KELI 155
K +NIA +V+ + +E E Y +EIS LY+ + K E+N++ E +
Sbjct: 386 DQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKL 445
Query: 156 EKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRK 215
+++ ++ EL A R ++ Q E+ +LQ+E +A V+ ++ ++ V Y +K
Sbjct: 446 KQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAV----NYDQK 501
Query: 216 LQHFQ------EEKNKEIAILRNTIRDLEQRLSVGKD--SHLKRR 252
Q + E+ E+A T+ ++ LS ++ +H K+R
Sbjct: 502 SQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKR 546
Score = 51.2 bits (121), Expect = 9e-07
Identities = 41/181 (22%), Positives = 93/181 (51%), Gaps = 14/181 (7%)
Query: 20 LINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQT 79
L+N Q+E +++N K N + +L L+ +AK IK + N+ + +Q
Sbjct: 601 LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAK---IKSLTDYMQNMEQKRRQL 657
Query: 80 IEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNI-------AKLVSEMKIKEEGYKKE 132
E Q +L E +L+ + + + E+E+ + L +M+ E ++K+
Sbjct: 658 EESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQ 717
Query: 133 ISKLYQDMQRKVELNEEKHKELIEKKEMEISELNA---KLRSQEKEKQNEIIKLQLEFDA 189
+S+L +++ K ++ +E ++L +K ++E +L++ KL+ +++E++ ++ KL L D
Sbjct: 718 LSRLRDEIEEKQKIIDE-IRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDK 776
Query: 190 K 190
+
Sbjct: 777 R 777
Score = 38.1 bits (87), Expect = 0.007
Identities = 24/100 (24%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 147 NEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTV 206
N E+ + +E+ + +SE AKLR+QEK + + E +L + K+ +
Sbjct: 649 NMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQME 708
Query: 207 LPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKD 246
+ ++++L ++E ++ I+ + IRDL Q+L + ++
Sbjct: 709 SHREAHQKQLSRLRDEIEEKQKII-DEIRDLNQKLQLEQE 747
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 54.3 bits (129), Expect = 1e-07
Identities = 64/277 (23%), Positives = 121/277 (43%), Gaps = 55/277 (19%)
Query: 1 MDQSSEGCMKKISSVNLDK--LINDFSQIEKKMVETNGKN----NILD------IQL-EK 47
M QS G + ++ +K L N+ + ++++ E N NIL +Q+ EK
Sbjct: 2376 MTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEK 2435
Query: 48 SNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSH 107
S+ ++++Q + + E A LHN + + +QNL + E L++ K +L
Sbjct: 2436 SSTAMEMLQTQLKELNERVAALHNDQEACKAK---EQNLSSQVECLELE----KAQLLQG 2488
Query: 108 EQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNA 167
E KNN L S ++ L Q++ E K+ +EKK+ EIS L
Sbjct: 2489 LDEAKNNYIVLQSS-----------VNGLIQEV--------EDGKQKLEKKDEEISRLKN 2529
Query: 168 KLRSQE----------------KEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSI 211
+++ QE KE+ E+ L +E + K+ +Q+K+ S QD+ + QS
Sbjct: 2530 QIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSS 2589
Query: 212 YRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSH 248
Y+ + K +++ + + + + ++ H
Sbjct: 2590 YKNLENELELTKMDKMSFVEKVNKMTAKETELQREMH 2626
Score = 48.9 bits (115), Expect = 4e-06
Identities = 47/207 (22%), Positives = 96/207 (46%), Gaps = 28/207 (13%)
Query: 35 NGKNNILDIQLEKSNCLLKV--MQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQ 92
N +N + +++K + + KV M AKE ++ E +H + Q+T E Q+ L GE +
Sbjct: 2592 NLENELELTKMDKMSFVEKVNKMTAKETELQRE---MHEMA---QKTAELQEELSGEKNR 2645
Query: 93 LKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHK 152
L L+ E++KS + + K E+ ++ KK + +++D K E K +
Sbjct: 2646 LAGELQLLLEEIKSSKDQLK--------ELTLENSELKKSLDCMHKDQVEK----EGKVR 2693
Query: 153 ELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIY 212
E EI+E +L EK+ Q ++ +++ ++ + K S ++ + Q +
Sbjct: 2694 E-------EIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTS-KEECLSSQKLE 2745
Query: 213 RRKLQHFQEEKNKEIAILRNTIRDLEQ 239
L+ +EE N + + +L++
Sbjct: 2746 IDLLKSSKEELNNSLKATTQILEELKK 2772
Score = 47.4 bits (111), Expect = 1e-05
Identities = 47/213 (22%), Positives = 94/213 (44%), Gaps = 22/213 (10%)
Query: 22 NDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIE 81
N + + +K KN+ L+ L + L + + + +KE A H Q+ +
Sbjct: 1034 NAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEH------QEFLT 1087
Query: 82 YQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMK-----IKEEGYK--KEIS 134
+ N+ L + + +++ L+S + +NN +K +KEE K KE++
Sbjct: 1088 KLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVN 1147
Query: 135 KLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARV 194
L Q+ ++ +++ + KH E + +E + ++ +E E+ K Q++ + K
Sbjct: 1148 DLLQENEQLMKVMKTKH----ECQNLESEPIRNSVKERESERNQCNFKPQMDLEVK---- 1199
Query: 195 QTKSKSYQDSTVLPQSIYRRKLQHFQE-EKNKE 226
+ SY V +++ R K QE EK KE
Sbjct: 1200 EISLDSYNAQLVQLEAMLRNKELKLQESEKEKE 1232
Score = 46.2 bits (108), Expect = 3e-05
Identities = 56/238 (23%), Positives = 113/238 (47%), Gaps = 30/238 (12%)
Query: 11 KISSVNLDKLINDFSQ--IEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKE--EC 66
K++ +L+K D SQ ++K+ N+ L ++S LL ++ K+ +E E
Sbjct: 557 KLAVADLEKQ-RDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEE 615
Query: 67 ATLHNIIKGLQQTIEYQQNLKGENEQLKIS---ADLIKEKLKSHEQEYKNNIAKLVSEMK 123
TL + K + + Q + EN Q KI+ L +++KSHE Y + L + +
Sbjct: 616 KTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHE--YNERVRTLEMDRE 673
Query: 124 ------------IKEEGYKKEISKL-YQDMQRKVELNEEKHKELIEKKEMEISELNAKLR 170
+ + + E KL Y ++Q+K E +++KH++ IE ++ S+L ++
Sbjct: 674 NLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVE 733
Query: 171 SQEKEKQ---NEII---KLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEE 222
E + Q NEI+ + + A+ ++ KS +D++++ ++R L F ++
Sbjct: 734 DLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKS-KDASLVTNEDHQRSLLAFDQQ 790
Score = 45.1 bits (105), Expect = 6e-05
Identities = 61/264 (23%), Positives = 118/264 (44%), Gaps = 47/264 (17%)
Query: 19 KLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQ 78
+L+ND + E+ ++ K+N L LE S LK +Q ++ E + +II ++
Sbjct: 914 QLLNDKVETEQAEIQELKKSNHL---LEDS---LKELQLLSETLSLEKKEMSSIISLNKR 967
Query: 79 TIEYQQNLKGENEQLK-ISADLIKEKLKSHEQE-----YKNNIAKLVSEMKIKEEGYK-- 130
IE L EN LK I+A L +EK+ ++ Y + K +SE+ + + K
Sbjct: 968 EIE---ELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLI 1024
Query: 131 -----KEISKLYQDMQRKVELNEEKHKEL----------IEKKEMEISELN--------- 166
+E Y+D+ +K + +EK+ +L E ++ E+ +L
Sbjct: 1025 LLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQE 1084
Query: 167 --AKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKN 224
KL E+ QN L LE + ++++ Q+++ ++++ +EE+N
Sbjct: 1085 FLTKLAFAEERNQN----LMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQN 1140
Query: 225 KEIAILRNTIRDLEQRLSVGKDSH 248
K + + +++ EQ + V K H
Sbjct: 1141 KMQKEVNDLLQENEQLMKVMKTKH 1164
Score = 43.5 bits (101), Expect = 2e-04
Identities = 45/197 (22%), Positives = 95/197 (48%), Gaps = 33/197 (16%)
Query: 35 NGKNNILDIQLEKS------NCLLKVMQAKEVSIKEECAT----LHNIIKGLQQTI---- 80
+ K+ + ++ LE S +C+ K KE ++EE A LH K Q +
Sbjct: 2659 SSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTN 2718
Query: 81 -EYQQNLKGENEQLKISADLIKEK------LKSHEQEYKNNI---AKLVSEMKIKEEGYK 130
+Y+ ++ E+L + + + LKS ++E N++ +++ E+K +
Sbjct: 2719 KQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNL 2778
Query: 131 KEISKLYQDMQR---KVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEF 187
K +++L ++ +R K++L + K+L E+KE+ EL+ +QEK+K ++
Sbjct: 2779 KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVM------ 2832
Query: 188 DAKLARVQTKSKSYQDS 204
D K+ + T+ K +++
Sbjct: 2833 DTKVDELTTEIKELKET 2849
Score = 40.4 bits (93), Expect = 0.002
Identities = 61/269 (22%), Positives = 105/269 (39%), Gaps = 38/269 (14%)
Query: 16 NLDKLINDFSQIEKKMVETNGKNNILDIQLE---KSNCLLKVMQAKEVSIKEECATLHNI 72
NL++ + E+ + K N L +E K N LLK E +E C L
Sbjct: 452 NLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLK--SHSEQKAREVCH-LEAE 508
Query: 73 IKGLQQTIEYQQN----LKGENEQLKISADLIKEKLKSHE-----QEYKNNIAKLVSEMK 123
+K ++Q + QN +K +N + ++EK+ E ++ K +A L +
Sbjct: 509 LKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRD 568
Query: 124 IKEEGYKK----------EISKLYQDMQRKVELNEEKHKELIEKKEMEI------SELNA 167
++ KK ++SK ++ + + E K KE E KE + SE
Sbjct: 569 CSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEK 628
Query: 168 KLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQ------SIYRRKLQHFQE 221
L E EK+N K+ + L Q KS Y + + S+ R L + +
Sbjct: 629 LLTQMESEKENLQSKIN-HLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLD 687
Query: 222 EKNKEIAILRNTIRDLEQRLSVGKDSHLK 250
K+ E+ + +L+Q+ H K
Sbjct: 688 SKSVEVETQKLAYMELQQKAEFSDQKHQK 716
Score = 40.4 bits (93), Expect = 0.002
Identities = 52/230 (22%), Positives = 97/230 (42%), Gaps = 39/230 (16%)
Query: 3 QSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSI 62
+ S CM K K+ + ++ + ++ E K+ L + K + ++++
Sbjct: 2675 KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTS 2734
Query: 63 KEECAT---------------LHNIIKGLQQTIE-----------YQQNLKGENEQLKIS 96
KEEC + L+N +K Q +E Y LK ENE+ +
Sbjct: 2735 KEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGK 2794
Query: 97 ADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYK------KEISKLYQDMQRKVELNEEK 150
L+ + K E+E K + K +S+++ +E K ++ +L +++ E EEK
Sbjct: 2795 MKLLIKSCKQLEEE-KEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEK 2853
Query: 151 HKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKS 200
KE E + S L + ++ EK E+++ Q+ A L Q+K S
Sbjct: 2854 TKEADEYLDKYCSLL---ISHEKLEKAKEMLETQV---AHLCSQQSKQDS 2897
Score = 37.7 bits (86), Expect = 0.010
Identities = 50/228 (21%), Positives = 96/228 (42%), Gaps = 28/228 (12%)
Query: 28 EKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLK 87
EK+M K L +QLEK+ +V + E+ L+ L +T
Sbjct: 305 EKEMKGQVNKFQELQLQLEKA----------KVELIEKEKVLNKCRDELVRTTAQYDQAS 354
Query: 88 GENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDM----QRK 143
+ L+ + E L Q ++ L ++K KE+ +++E+S+ + Q
Sbjct: 355 TKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQEC 414
Query: 144 VELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQD 203
+++ +EL + K M + L A+L KQ L+ EF KL R + +++Q
Sbjct: 415 IQMKARLTQELQQAKNMH-NVLQAELDKLTSVKQQLENNLE-EFKQKLCRAE---QAFQA 469
Query: 204 STVLPQSIYR---------RKLQHFQEEKNKEIAILRNTIRDLEQRLS 242
S + + R L+ E+K +E+ L +++++Q L+
Sbjct: 470 SQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLN 517
Score = 35.8 bits (81), Expect = 0.037
Identities = 45/238 (18%), Positives = 99/238 (41%), Gaps = 15/238 (6%)
Query: 8 CMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECA 67
C K + L ++ ++ ++ K+ I+ + N ++ ++ ++ E
Sbjct: 621 CWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIR 680
Query: 68 TLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEE 127
LHN++ +E Q+ E +Q +D + H++E +N K S++ + E
Sbjct: 681 NLHNVLDSKSVEVETQKLAYMELQQKAEFSD------QKHQKEIENMCLK-TSQLTGQVE 733
Query: 128 GYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEF 187
+ ++ L ++ K ++ H E +++ + +A L + E +++ L F
Sbjct: 734 DLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDL-LKSKDASLVTNEDHQRS-----LLAF 787
Query: 188 DAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGK 245
D + A + + + +P +L+ Q KN AIL+N + LE L K
Sbjct: 788 DQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNS--AILQNRVDSLEFSLESQK 843
Score = 34.7 bits (78), Expect = 0.082
Identities = 60/254 (23%), Positives = 106/254 (41%), Gaps = 60/254 (23%)
Query: 46 EKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNL--------------KGENE 91
E+S C L+ Q+ + S A L N + L+ ++E Q+ + KGE E
Sbjct: 810 ERSECRLEADQSPKNS-----AILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIE 864
Query: 92 QLKISADLIKE-----------KLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKL---- 136
+ + A+ + + KL+ ++N +A+ +S ++ KE+ + K+
Sbjct: 865 ENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQ 924
Query: 137 --YQDMQRKVELNEEKHKEL--------IEKKEM-EISELNAKLRSQEKEKQNEIIKLQL 185
Q++++ L E+ KEL +EKKEM I LN K +E ++N +K
Sbjct: 925 AEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLN-KREIEELTQENGTLK--- 980
Query: 186 EFDAKLARVQTKSKSYQDSTVLPQSIYRRK--LQHFQEEKNKEIAIL-------RNTIRD 236
E +A L Q K Q S I R+ + ++ +E IL N D
Sbjct: 981 EINASLN--QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYED 1038
Query: 237 LEQRLSVGKDSHLK 250
L Q+ ++ + K
Sbjct: 1039 LSQKYKAAQEKNSK 1052
Score = 34.7 bits (78), Expect = 0.082
Identities = 52/266 (19%), Positives = 113/266 (42%), Gaps = 27/266 (10%)
Query: 4 SSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIK 63
S E ++ VN D F +E ++ + ++ + L+V+Q +++ ++
Sbjct: 1878 SREDIGDNVAKVN-DSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLE 1936
Query: 64 EECATLHNIIKGLQQTIEY----QQNLKGENEQLK---ISADLIKEKLK-------SHEQ 109
++ +I L++ + + L+GE + + + D + EK+K SH+
Sbjct: 1937 KDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQS 1996
Query: 110 EYKNNIAKLVSEMKIKEE---GYKKEISKLYQD---MQRKVELNEEKHKELIEKKEMEIS 163
E + I +E+K K E ++S+L +D +Q K++ + EK + + + E+
Sbjct: 1997 ECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQ-SLEKDSQALSLTKCELE 2055
Query: 164 ELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEK 223
A+L +++ E LQ SK+ ++ ++ + + +L QEE
Sbjct: 2056 NQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKAL-EAALVEKGEFALRLSSTQEEV 2114
Query: 224 NKEIAILRNTIRDLEQRLSVGKDSHL 249
++ LR I L R+ + L
Sbjct: 2115 HQ----LRRGIEKLRVRIEADEKKQL 2136
Score = 33.9 bits (76), Expect = 0.14
Identities = 32/145 (22%), Positives = 74/145 (51%), Gaps = 8/145 (5%)
Query: 96 SADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHK-EL 154
S+ + ++LK+ QE +N I +E++++ +G++KE+ Q +++L EK K EL
Sbjct: 275 SSPHLLDQLKAQNQELRNKI----NELELRLQGHEKEMKGQVNKFQ-ELQLQLEKAKVEL 329
Query: 155 IEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRR 214
IEK+++ + +R+ + Q LE KL ++ + + + +
Sbjct: 330 IEKEKVLNKCRDELVRTTAQYDQASTKYTALE--QKLKKLTEDLSCQRQNAESARCSLEQ 387
Query: 215 KLQHFQEEKNKEIAILRNTIRDLEQ 239
K++ ++E +E++ + + + L+Q
Sbjct: 388 KIKEKEKEFQEELSRQQRSFQTLDQ 412
Score = 28.5 bits (62), Expect = 5.9
Identities = 39/194 (20%), Positives = 91/194 (46%), Gaps = 26/194 (13%)
Query: 69 LHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMK--IKE 126
+HN+ +++T L E + + ++K + + +L+++++ I+
Sbjct: 1769 IHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIEL 1828
Query: 127 EGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISE-LNAKL-----RSQEKEKQNEI 180
E E+ K D+ K+E H+EL+++ +E SE LN+ L +S ++ + +
Sbjct: 1829 EKIVGELKKENSDLSEKLEYFSCDHQELLQR--VETSEGLNSDLEMHADKSSREDIGDNV 1886
Query: 181 IKLQ-------LEFDAKLARVQTKSKSYQDSTVLPQS----IYRRKLQHFQEEKNKEIAI 229
K+ L+ + +L+R++++ S + + ++ + KL ++ +NK+ I
Sbjct: 1887 AKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVI 1946
Query: 230 LRNTIRDLEQRLSV 243
+ LE+ LSV
Sbjct: 1947 V-----CLEEELSV 1955
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 54.3 bits (129), Expect = 1e-07
Identities = 60/258 (23%), Positives = 120/258 (46%), Gaps = 47/258 (18%)
Query: 9 MKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQ-----------A 57
+KK+ L++ F Q+++ + E KN +L +LE L+ ++
Sbjct: 938 LKKVPDPVLEE---SFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVV 994
Query: 58 KEVSIKEECATLHNIIKGLQQTIEYQQNLKGENE------QLKISADLIKEKLKSHEQEY 111
KEV E + + L++ +E + KG E Q +++A L +EK ++ E+
Sbjct: 995 KEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEVLLLQQRVAA-LAEEKSRAQEKVT 1053
Query: 112 KNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRS 171
+ + KL ++ +++ E YQ +Q + ++ +L EK+E E+S L KL+
Sbjct: 1054 EKEVVKLQNDPQLEAE---------YQQLQE----DHQRQDQLREKQEEELSFLQDKLKR 1100
Query: 172 QEKEKQNEIIK------LQLEFDAKLAR-VQTKSKSYQDSTVLPQSIYRRKLQHFQ---- 220
EKE+ K L++E DA R V ++ Y+D ++ R K + +
Sbjct: 1101 LEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWA 1160
Query: 221 -EEKNKEIAILRNTIRDL 237
EE+N ++ +++ +R++
Sbjct: 1161 LEEENAKV-VVQEKVREI 1177
Score = 36.6 bits (83), Expect = 0.022
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 9/169 (5%)
Query: 92 QLKISADLIKE-KLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEK 150
QLK +K+ K + +E I + + + KEE +KL ++ +++V+L E+
Sbjct: 1271 QLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLR-AKLSEEQKKQVDLERER 1329
Query: 151 --HKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLP 208
+E I +KE E+S + ++ QE + E L+ E A + + +
Sbjct: 1330 ASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAEL 1389
Query: 209 QSIYRRK--LQHFQEEKNKEIAILRNTIRD---LEQRLSVGKDSHLKRR 252
+ + RR+ L+ EE +E R R+ L+QRL+ + + R
Sbjct: 1390 RRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAR 1438
Score = 28.1 bits (61), Expect = 7.7
Identities = 22/113 (19%), Positives = 51/113 (45%), Gaps = 11/113 (9%)
Query: 147 NEEKHKELIEKKEM---EISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQD 203
N+ K+ ++ + + E+SEL +L+ + + I+ + + + LAR+Q +
Sbjct: 9 NKGKYSPTVQTRSISNKELSELIEQLQKNADQVEKNIVDTEAKMQSDLARLQEGRQPEHR 68
Query: 204 STVLPQSIYRRKLQHFQEE--------KNKEIAILRNTIRDLEQRLSVGKDSH 248
L + + KL + E K+ + ++ IR L++R++ + H
Sbjct: 69 DVTLQKVLDSEKLLYVLEADAAIAKHMKHPQGDMIAEDIRQLKERVTNLRGKH 121
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 53.5 bits (127), Expect = 2e-07
Identities = 54/263 (20%), Positives = 122/263 (46%), Gaps = 45/263 (17%)
Query: 11 KISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLH 70
K + L L D ++ +KK+ E L Q++ + L ++ + +++ ++ LH
Sbjct: 1826 KANEHQLITLKKDVNETQKKVSEMEQ----LKKQIKDQSLTLSKLEIENLNLAQK---LH 1878
Query: 71 NIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHE-----------------QEYKN 113
++ ++ ++ + NL+ E LK+ D +KE L+ + +E+K
Sbjct: 1879 ENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKE 1938
Query: 114 NIAKL---VSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLR 170
+ KL +SE I+ +K++ K ++Q+K++ ++K +L+ KE ++N
Sbjct: 1939 TVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKE----DVN---- 1990
Query: 171 SQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAIL 230
+K NE+ +L+ +F+A+ +Q +V + K H E+ + +A
Sbjct: 1991 -MSHKKINEMEQLKKQFEAQNLSMQ---------SVRMDNFQLTKKLHESLEEIRIVAKE 2040
Query: 231 RNTIRDLEQRLSVGKDSHLKRRR 253
R+ +R +++ L + +D + R
Sbjct: 2041 RDELRRIKESLKMERDQFIATLR 2063
Score = 47.4 bits (111), Expect = 1e-05
Identities = 52/236 (22%), Positives = 103/236 (43%), Gaps = 26/236 (11%)
Query: 4 SSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIK 63
SS G +K S +L ++++++ E L QLE + L+ ++ ++ I
Sbjct: 859 SSLGALKTELSYKTQELQEKTREVQERLNEMEQ----LKEQLENRDSTLQTVEREKTLIT 914
Query: 64 EECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMK 123
E+ LQQT+E + L E + LK ++E L+ + K++I V+
Sbjct: 915 EK----------LQQTLEEVKTLTQEKDDLK----QLQESLQIERDQLKSDIHDTVNMNI 960
Query: 124 IKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKL 183
+E + + L Q + L + +E+ ME + K E Q +++ +
Sbjct: 961 DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETK-----DEFQQKMVGI 1015
Query: 184 QLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQ 239
+ D + QT + +D+ ++ Q +RK+ +EKN+ +L + I + EQ
Sbjct: 1016 DKKQDLEAKNTQTLTADVKDNEIIEQ---QRKIFSLIQEKNELQQMLESVIAEKEQ 1068
Score = 45.8 bits (107), Expect = 4e-05
Identities = 56/250 (22%), Positives = 116/250 (46%), Gaps = 30/250 (12%)
Query: 17 LDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGL 76
L + + + + K+ + L ++ ++ L+ +++ +EE +H +K
Sbjct: 1674 LHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEH 1733
Query: 77 QQTIE---------------YQQNLKGENEQLKISADLIKEKLK---SHEQEYKNNIAKL 118
Q+TI+ Q++L+ N+ LK I+E+L+ H +E + I KL
Sbjct: 1734 QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKL 1793
Query: 119 ---VSEMKIKEEGYKKEISKLYQDMQRKV-ELNEEKHKELIEKKEM-----EISELNAKL 169
VSE K +K++ +Q K+ EL +H+ + KK++ ++SE+ +L
Sbjct: 1794 RGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEME-QL 1852
Query: 170 RSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAI 229
+ Q K++ + KL++E + LA+ ++ S + + RR + + E+++
Sbjct: 1853 KKQIKDQSLTLSKLEIE-NLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKES 1911
Query: 230 LRNT-IRDLE 238
L+ T RDLE
Sbjct: 1912 LQETKARDLE 1921
Score = 45.4 bits (106), Expect = 5e-05
Identities = 56/277 (20%), Positives = 111/277 (40%), Gaps = 44/277 (15%)
Query: 14 SVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNII 73
S L + ++ + K+ + +L + ++ +K + AK + +EE H +
Sbjct: 1427 SKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCL 1486
Query: 74 KGLQQTIE---------------YQQNLKGENEQLKISADLIKEKLK-------SHEQEY 111
K ++TI Q+ L+ N++L+ I EK + S QE
Sbjct: 1487 KEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEK 1546
Query: 112 KNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEME---------- 161
N + + K K+ + SK+ + R E EE + EK+EM+
Sbjct: 1547 VNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIER 1606
Query: 162 ------ISELNAKLR-SQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQD-----STVLPQ 209
E+ AK++ SQEKE Q + E K+ ++ + ++ + +
Sbjct: 1607 DQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETE 1666
Query: 210 SIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKD 246
+I ++ H E+ + + R+ +R +E+ L V +D
Sbjct: 1667 NIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERD 1703
Score = 44.3 bits (103), Expect = 1e-04
Identities = 51/236 (21%), Positives = 104/236 (44%), Gaps = 31/236 (13%)
Query: 40 ILDIQLEKSNCLLKV---MQAKEVSIKEECATL-HNIIKGLQQTIEYQQNLKGENEQLKI 95
IL LE+ + K +++ E ++K E L N+ + + + +E Q+ LK + LK
Sbjct: 1673 ILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKE 1732
Query: 96 SADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELI 155
+ I +KL+ E N I+ + +++ + K + K+ +++ R ++ ++ +E I
Sbjct: 1733 HQETI-DKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEEL-RIAHMHLKEQQETI 1790
Query: 156 EKKEMEISELNAKLRSQEKEKQNEIIKLQ---------------LEFDAKLARVQTKSKS 200
+K +SE KL + +K+ +N KLQ L+ D + +
Sbjct: 1791 DKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEME 1850
Query: 201 YQDSTVLPQSIYRRKLQ----------HFQEEKNKEIAILRNTIRDLEQRLSVGKD 246
+ QS+ KL+ H E+ K + R+ +R +E+ L + +D
Sbjct: 1851 QLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERD 1906
Score = 40.0 bits (92), Expect = 0.002
Identities = 51/239 (21%), Positives = 107/239 (44%), Gaps = 39/239 (16%)
Query: 29 KKMVETNGKNNILDIQLEKS----NCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQ 84
K++ ET N L++ E+S + L ++ + + + E+ IK L + +
Sbjct: 1296 KEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKE---RD 1352
Query: 85 NLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQR-- 142
NLK E L++ D +KE ++ + + + +K + +KE+ E +K+ +M++
Sbjct: 1353 NLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK--DNETTKIVSEMEQFK 1410
Query: 143 -------KVELN--------EEKHKEL--IEKKEMEISELNAKLRS---QEKEKQNEIIK 182
++E+ +E H E+ + K++ ++ L L+S Q KE EI+
Sbjct: 1411 PKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVA 1470
Query: 183 LQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRL 241
LE + +L +V Q+ T+ +L+ EK EI+ ++ + + +L
Sbjct: 1471 KHLETEEEL-KVAHCCLKEQEETI-------NELRVNLSEKETEISTIQKQLEAINDKL 1521
Score = 38.9 bits (89), Expect = 0.004
Identities = 40/184 (21%), Positives = 84/184 (45%), Gaps = 23/184 (12%)
Query: 18 DKLINDFSQIEKKMVETNGKNNILDIQLEKSNCL-------LKVMQAKEVSIKEECATLH 70
D L+ D+ Q+ + E ++++L++ N L K + +E+ + E + L
Sbjct: 508 DNLVLDYEQLRTEKEE-------MELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLK 560
Query: 71 NIIKGLQQTIEYQQNLKGEN----EQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKE 126
N++K + Y Q+L+ E E L+ D IK KL+ + K K+ ++
Sbjct: 561 NLVKHAEV---YNQDLENELSSKVELLREKEDQIK-KLQEYIDSQKLENIKMDLSYSLES 616
Query: 127 EGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLE 186
K++ + D + V L+ ++ + + +E+ E +L + K+ +N+I Q +
Sbjct: 617 IEDPKQMKQTLFDAET-VALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQ 675
Query: 187 FDAK 190
+AK
Sbjct: 676 LEAK 679
Score = 36.6 bits (83), Expect = 0.022
Identities = 39/150 (26%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Query: 70 HNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYK---NNIAKLVSEMKIKE 126
H + Q T E + L+ + K SA + K+ ++E + + IAKL + K+ E
Sbjct: 2370 HVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKL--QAKVHE 2427
Query: 127 EGYKKEISK-LYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEI--IKL 183
E +K Q +Q KV L + +KE IE +M++ +++ + KE + EI K
Sbjct: 2428 SNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKA 2487
Query: 184 QLEFDAKLARV----QTKSKSYQDSTVLPQ 209
+E+ ++ R+ +S+ QD++V+ +
Sbjct: 2488 TVEYQKEVIRLLRENLRRSQQAQDTSVISE 2517
Score = 36.2 bits (82), Expect = 0.028
Identities = 54/243 (22%), Positives = 109/243 (44%), Gaps = 47/243 (19%)
Query: 26 QIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQN 85
+ ++KMV + K + LE N K+ I E+ + ++I+
Sbjct: 1007 EFQQKMVGIDKKQD-----LEAKNTQTLTADVKDNEIIEQQRKIFSLIQE---------- 1051
Query: 86 LKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVE 145
K E +Q+ S KE+LK+ + K NI EM I+ + +E+ L +++++ E
Sbjct: 1052 -KNELQQMLESVIAEKEQLKT---DLKENI-----EMTIENQ---EELRLLGDELKKQQE 1099
Query: 146 LNEEKHKELIEKKEMEIS-------ELNAKLR---SQEKEKQNEIIKLQ---LEFDAKLA 192
+ ++ I KKE E+S E+ KL+ Q +EKQ +++ +Q E K+
Sbjct: 1100 IVAQEKNHAI-KKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKIN 1158
Query: 193 RVQTKSKSYQDSTVLPQSIYRRKLQHFQE-----EKNKEIAILRNTIRDLEQRLSVGKDS 247
++ ++ + + + +L+ Q+ E+ K I R +++L++ +D
Sbjct: 1159 EIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERD- 1217
Query: 248 HLK 250
HL+
Sbjct: 1218 HLR 1220
Score = 32.0 bits (71), Expect = 0.53
Identities = 44/221 (19%), Positives = 88/221 (39%), Gaps = 17/221 (7%)
Query: 38 NNILDIQLEKSNCLLKVMQAKEV-SIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKIS 96
N +D+ +E+ +LK E SIK E + + K + Q +E N + + E+LK
Sbjct: 2232 NQNMDLHIEE---ILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNG 2288
Query: 97 ADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIE 156
+++ + N I +++E EE + QD++ E NE+ K
Sbjct: 2289 IQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQT 2348
Query: 157 KKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRR-- 214
K S +Q+ + + + K+ ++ ++S + +S +
Sbjct: 2349 LKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQ 2408
Query: 215 -----------KLQHFQEEKNKEIAILRNTIRDLEQRLSVG 244
KLQ E NK + + TI+ L+ ++++G
Sbjct: 2409 KELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALG 2449
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 53.1 bits (126), Expect = 2e-07
Identities = 53/230 (23%), Positives = 112/230 (48%), Gaps = 13/230 (5%)
Query: 19 KLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQ 78
K+ +I +M + +++ + +L+ +C + Q + + C +L ++K ++
Sbjct: 39 KIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCG-NLQQGSDSEMDPSCCSLDLLMKKIKG 97
Query: 79 TIEYQQNLKGENEQLKISADLIKEK----LKSHEQEYKNNIAKLVSEMKIKEEGYKK--E 132
+ ENE LKI +E L++ Q N E++ K+E K+ +
Sbjct: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
Query: 133 ISKLYQDMQRKVEL-NEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKL 191
++KL ++ + K + N + E +E+K +I+EL ++ EKEK+ +++ +L + KL
Sbjct: 158 VNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRT-LLERKLSLENKL 216
Query: 192 ARVQ---TKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLE 238
+++ T KS QD SI + ++ H Q + + LR+ I+++E
Sbjct: 217 LQLKSSATYGKSCQD-LQREISILQEQISHLQFVIHSQHQNLRSVIQEME 265
Score = 36.2 bits (82), Expect = 0.028
Identities = 56/248 (22%), Positives = 104/248 (41%), Gaps = 56/248 (22%)
Query: 13 SSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSN-----CLLKVMQ---------AK 58
S +LD L+ + +++E N +N +L I+L+ S L V Q ++
Sbjct: 84 SCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSE 143
Query: 59 EVSIKEECATLHNIIKGLQQT--IEYQQNLKGENEQLKISADLIKEK----------LKS 106
EV K+E + K L Q +E +Q LK E L A+ ++EK ++
Sbjct: 144 EVRKKQEDS------KQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQR 197
Query: 107 HEQEYKNNIAKLVS-EMKIKEEGYKKEISKLYQDMQRKVELNEEKHKEL----------I 155
E+E + + + +S E K+ + K QD+QR++ + +E+ L +
Sbjct: 198 MEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNL 257
Query: 156 EKKEMEISELNAKLRSQEK------------EKQNEIIKLQLEFDAKLARVQTKSKSYQD 203
E+ L L+ Q+K E QN+ +K Q+ ++ R + SK+
Sbjct: 258 RSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKV-SKAVST 316
Query: 204 STVLPQSI 211
S + + +
Sbjct: 317 SELKTEGV 324
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 53.1 bits (126), Expect = 2e-07
Identities = 53/230 (23%), Positives = 112/230 (48%), Gaps = 13/230 (5%)
Query: 19 KLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQ 78
K+ +I +M + +++ + +L+ +C + Q + + C +L ++K ++
Sbjct: 39 KIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCG-NLQQGSDSEMDPSCCSLDLLMKKIKG 97
Query: 79 TIEYQQNLKGENEQLKISADLIKEK----LKSHEQEYKNNIAKLVSEMKIKEEGYKK--E 132
+ ENE LKI +E L++ Q N E++ K+E K+ +
Sbjct: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
Query: 133 ISKLYQDMQRKVEL-NEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKL 191
++KL ++ + K + N + E +E+K +I+EL ++ EKEK+ +++ +L + KL
Sbjct: 158 VNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRT-LLERKLSLENKL 216
Query: 192 ARVQ---TKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLE 238
+++ T KS QD SI + ++ H Q + + LR+ I+++E
Sbjct: 217 LQLKSSATYGKSCQD-LQREISILQEQISHLQFVIHSQHQNLRSVIQEME 265
Score = 36.2 bits (82), Expect = 0.028
Identities = 56/248 (22%), Positives = 104/248 (41%), Gaps = 56/248 (22%)
Query: 13 SSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSN-----CLLKVMQ---------AK 58
S +LD L+ + +++E N +N +L I+L+ S L V Q ++
Sbjct: 84 SCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSE 143
Query: 59 EVSIKEECATLHNIIKGLQQT--IEYQQNLKGENEQLKISADLIKEK----------LKS 106
EV K+E + K L Q +E +Q LK E L A+ ++EK ++
Sbjct: 144 EVRKKQEDS------KQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQR 197
Query: 107 HEQEYKNNIAKLVS-EMKIKEEGYKKEISKLYQDMQRKVELNEEKHKEL----------I 155
E+E + + + +S E K+ + K QD+QR++ + +E+ L +
Sbjct: 198 MEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNL 257
Query: 156 EKKEMEISELNAKLRSQEK------------EKQNEIIKLQLEFDAKLARVQTKSKSYQD 203
E+ L L+ Q+K E QN+ +K Q+ ++ R + SK+
Sbjct: 258 RSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKV-SKAVST 316
Query: 204 STVLPQSI 211
S + + +
Sbjct: 317 SELKTEGV 324
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 52.8 bits (125), Expect = 3e-07
Identities = 56/260 (21%), Positives = 125/260 (48%), Gaps = 40/260 (15%)
Query: 1 MDQSSEGCMKKISSVNLD------KLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKV 54
++QS +K+I ++ + K D + ++K++ E ++ QLE S LK
Sbjct: 120 LEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEA------MNTQLELSE-QLKF 172
Query: 55 MQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNN 114
E ++K+ + I G ++ I Y Q +QL + D E K
Sbjct: 173 QNNSEDNVKKLQEEIEKIRPGFEEQILYLQ------KQLDATTD-----------EKKET 215
Query: 115 IAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELI-------EKKEMEISELNA 167
+ +L + ++ + Y+K I+ L +++ + +++E+ KEL+ ++ E EI++LN
Sbjct: 216 VTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNE 275
Query: 168 KLRSQEKEKQNEIIKLQLEFDAKLARV-QTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKE 226
+ K+ + +Q +++ +L + + S + QD+ + SI ++ ++ N++
Sbjct: 276 LKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQIC--SILLQENTFVEQVVNEK 333
Query: 227 IAILRNTIRDLEQRLSVGKD 246
+ L +T+++LE + S+ KD
Sbjct: 334 VKHLEDTLKELESQHSILKD 353
Score = 48.1 bits (113), Expect = 7e-06
Identities = 58/235 (24%), Positives = 99/235 (42%), Gaps = 26/235 (11%)
Query: 37 KNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKIS 96
K ++ IQ KS C + +E+ K +IIK L + ++ K E EQ +S
Sbjct: 35 KKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQCLS 94
Query: 97 ADLIKEKLKSHEQEYKNNIAKLVSEMKIKEE---GYKKEISKLYQD-------------- 139
L KE +K +QE ++++ K+ K E+ Y KEI L +
Sbjct: 95 --LKKENIKM-KQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKAN 151
Query: 140 MQRKVELNEEKHKELIEK-KEMEISELNAKLRSQEKEK-----QNEIIKLQLEFDAKLAR 193
+Q+++E EL E+ K SE N K +E EK + +I+ LQ + DA
Sbjct: 152 LQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDE 211
Query: 194 VQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSH 248
+ Q+ Y++ + QEE + AI + +++L ++ H
Sbjct: 212 KKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEH 266
Score = 47.4 bits (111), Expect = 1e-05
Identities = 56/252 (22%), Positives = 110/252 (43%), Gaps = 24/252 (9%)
Query: 16 NLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHN---- 71
++ +L +EK+ E K N + + K+ L + + ++KEE +L +
Sbjct: 945 SVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQ 1004
Query: 72 ---IIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKE-- 126
++ L Q E +NL E E+ D+ KE+ + E ++ +L + E
Sbjct: 1005 LSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETI 1064
Query: 127 EGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNA-KLRSQEKEKQ-----NEI 180
+++ + +Q +L E + E+ K M EL A KL+ ++K K+ NE+
Sbjct: 1065 NSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNEL 1124
Query: 181 IKLQLEFDAKLARVQTK-------SKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNT 233
+LQ++ + ++Q K Q +T++ I + +E N+++ N
Sbjct: 1125 EELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEI--ADYERLMKELNQKLTNKNNK 1182
Query: 234 IRDLEQRLSVGK 245
I DLEQ + + K
Sbjct: 1183 IEDLEQEIKIQK 1194
Score = 47.0 bits (110), Expect = 2e-05
Identities = 52/222 (23%), Positives = 95/222 (42%), Gaps = 51/222 (22%)
Query: 41 LDIQLEKSNCLLKVMQAKEVSIKEECAT------------------LHNIIKGLQQTIEY 82
L E+ L Q + +++EEC +HN++K +
Sbjct: 1281 LKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMS 1340
Query: 83 QQNLKG---ENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQD 139
Q +G E E L++ D +K KL Q+ +NN+ VSE+ Q
Sbjct: 1341 QAETEGAKQEREHLEMLIDQLKIKL----QDSQNNLQINVSEL---------------QT 1381
Query: 140 MQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSK 199
+Q + + E+H +++++ + +EL KL S + E N ++K + QT S+
Sbjct: 1382 LQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSE--NMMMKSE--------HTQTVSQ 1431
Query: 200 SYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRL 241
+ VL S +R +++H QEE K + L+ + +E +L
Sbjct: 1432 LTSQNEVLRNS-FRDQVRHLQEEHRKTVETLQQQLSKMEAQL 1472
Score = 46.2 bits (108), Expect = 3e-05
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 7/166 (4%)
Query: 23 DFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEY 82
+ + K N N I I L+++ + +V+ K +++ L + L+ + Y
Sbjct: 298 ELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTY 357
Query: 83 QQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLV---SEMKIKEEGYKKEISKLYQD 139
NLK +L++ A IK++ ++ + I +L+ E E K E++ L +
Sbjct: 358 MNNLK---LKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQ 414
Query: 140 MQRKVELNEEKHKELIEKKEMEISELNAK-LRSQEKEKQNEIIKLQ 184
VE + + + L E+ + EISELN L EKEK + ++Q
Sbjct: 415 FCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQ 460
Score = 43.5 bits (101), Expect = 2e-04
Identities = 56/237 (23%), Positives = 107/237 (45%), Gaps = 34/237 (14%)
Query: 43 IQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQT-------IEYQQNLKGENEQLKI 95
+Q E K+ Q E +++ + +H + + L+ +E L+GENE+L
Sbjct: 490 LQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLS 549
Query: 96 SADLIKEKLKSHEQEYKNNIAKLVS----EMKIKE-EGYKKEISKLYQDMQRKVELNEEK 150
+L+ E + + + N L+S + +KE EG +++ D K++ + E+
Sbjct: 550 QQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEE 609
Query: 151 ----HKELIEKKEMEISELNAKL------RSQEKEKQNEI-------IKLQLEFDAKLAR 193
HK+ E++E I EL K+ S+ ++K NE+ +K + + D KL +
Sbjct: 610 MDNFHKK-CEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEK 668
Query: 194 VQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSHLK 250
+ + K + + + +++ EE NK + + RDLE LS +D LK
Sbjct: 669 LMVQMKVLSED----KEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILK 721
Score = 41.6 bits (96), Expect = 7e-04
Identities = 52/246 (21%), Positives = 113/246 (45%), Gaps = 33/246 (13%)
Query: 10 KKISSVNLDKLINDFSQIEKKMVETNGKNNILD----IQLEKSNCLLKVMQAKEVSIKEE 65
+ ++ +N +K F Q ++K++E + L +Q E+ LL+ + ++V +++E
Sbjct: 788 ESLAKINEEKCNLAF-QRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKE 846
Query: 66 CATLHNIIKGLQQTIEYQQNLKG----ENEQLKISADLIKE---KLKSHEQEYK------ 112
+ + + LQ + +N EN+ L I + + + K + H ++ K
Sbjct: 847 LEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEH 906
Query: 113 NNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQ 172
N+ L+ + ++++ + E+ L + + + K+ L KE+E E L +
Sbjct: 907 ENLKPLLEQKELRDR--RAELILLKDSLAKSPSV---KNDPLSSVKELE--EKIENLEKE 959
Query: 173 EKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRN 232
KEK+ +I K++L V K+K DS+ + +L+ + EK++ A +R+
Sbjct: 960 CKEKEEKINKIKL--------VAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRD 1011
Query: 233 TIRDLE 238
I+ E
Sbjct: 1012 LIQGAE 1017
Score = 37.4 bits (85), Expect = 0.013
Identities = 41/189 (21%), Positives = 83/189 (43%), Gaps = 40/189 (21%)
Query: 26 QIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEE-------------------- 65
++E + KN + + L + + +LK ++ K S+ EE
Sbjct: 556 ELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHK 615
Query: 66 -CATLHNII----KGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVS 120
C +I K ++QTI+Y L+ + +L ++E LK +Q + KL+
Sbjct: 616 KCEREERLILELGKKVEQTIQYNSELEQKVNEL---TGGLEETLKEKDQN-DQKLEKLMV 671
Query: 121 EMKI---KEEGYKKEISKLYQDMQR----KVELNEEKHKELIEKKEM----EISELNAKL 169
+MK+ +E E+ LY++ + K +L+ + L +K+++ I++L KL
Sbjct: 672 QMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL 731
Query: 170 RSQEKEKQN 178
+ +E+ N
Sbjct: 732 QLMVEEQDN 740
Score = 37.4 bits (85), Expect = 0.013
Identities = 46/240 (19%), Positives = 108/240 (45%), Gaps = 15/240 (6%)
Query: 14 SVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNII 73
S ++ LI + ++E ++ LD++ E++N E I++ L N
Sbjct: 1006 SASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNF-------EHRIEDLTRQLRNST 1058
Query: 74 KGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEI 133
+ ++L E L+ +A L++ ++ ++ +L +E KE+ K+
Sbjct: 1059 LQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHA 1118
Query: 134 SKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLAR 193
+ + + + +V+L +EK + +E+E+ + +A+ + + + +L E + KL
Sbjct: 1119 TTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTN 1178
Query: 194 VQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSHLKRRR 253
K + L Q I +K + QE +EI L+++++ E++ + K +K ++
Sbjct: 1179 KNNKIED------LEQEIKIQKQK--QETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKK 1230
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 52.8 bits (125), Expect = 3e-07
Identities = 58/243 (23%), Positives = 115/243 (47%), Gaps = 27/243 (11%)
Query: 21 INDFSQIEKKMVETNGKNNILDIQLEKS--------NCLLKVMQAKEVSIKE--ECATLH 70
+ +++++EK E K L +LEK+ L + QAKE + +E +
Sbjct: 621 VGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNRE 680
Query: 71 NIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYK 130
+ +G+++ + + L+ ++ + ++SA ++ LK EQ Y+ I L +++K K+ K
Sbjct: 681 DSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIK-KDLADK 739
Query: 131 KEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEK-----EKQNEIIKLQL 185
+ + + MQR E EK K L E+K M I+ +++K+RS E+ + N++
Sbjct: 740 ETLENM---MQRHEEEAHEKGKILSEQKAM-INAMDSKIRSLEQRIVELSEANKLAANSS 795
Query: 186 EFDAKLARVQ-------TKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLE 238
F + + Q + K Y ++ RKL+ E+ + + +N + +LE
Sbjct: 796 LFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELE 855
Query: 239 QRL 241
RL
Sbjct: 856 TRL 858
Score = 33.5 bits (75), Expect = 0.18
Identities = 41/192 (21%), Positives = 83/192 (43%), Gaps = 12/192 (6%)
Query: 18 DKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQ 77
D+++ S+++ E + L Q + L E + + A +++ +
Sbjct: 982 DEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKER 1041
Query: 78 QTIEYQQNLKGENEQLKISADLIKEKLKSHEQ-----EYKNNIAKLVSEMKIKEEGYKKE 132
Q ++ L E Q + ++ L + +Q + + ++ V E+ +KE +K E
Sbjct: 1042 QWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKE--HKAE 1099
Query: 133 ISKLYQDMQR---KVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDA 189
I L Q ++ K E +K +L +K M E+NA+ Q+ E + E+ + LE A
Sbjct: 1100 ILALQQALKEQKLKAESLSDKLNDLEKKHAM--LEMNARSLQQKLETERELKQRLLEEQA 1157
Query: 190 KLARVQTKSKSY 201
KL + K++
Sbjct: 1158 KLQQQMDLQKNH 1169
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 52.8 bits (125), Expect = 3e-07
Identities = 52/231 (22%), Positives = 106/231 (45%), Gaps = 20/231 (8%)
Query: 18 DKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATL-------H 70
++L++ + +EK++ ET KN+ L ++ +L + S+K E ++
Sbjct: 773 EELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEF 832
Query: 71 NIIKGLQQTIEYQ-QNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKL---VSEMKIKE 126
N + ++ Q NL+ ENE+L S +++ + ++ K I +L + K +
Sbjct: 833 NKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKEN 892
Query: 127 EGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLE 186
E K +++ L + ++ + E N + + E KE E+ L + +EKQ E K
Sbjct: 893 ETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKC--- 949
Query: 187 FDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDL 237
+ ++A+VQ +S +L L+ ++ K +A L N I++L
Sbjct: 950 -EQQMAKVQKLEES-----LLATEKVISSLEKSRDSDKKVVADLMNQIQEL 994
Score = 38.5 bits (88), Expect = 0.006
Identities = 43/216 (19%), Positives = 96/216 (44%), Gaps = 15/216 (6%)
Query: 28 EKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLK 87
E+++ + L+ + K N +V A+ + +KE+ + N+ QQ IE L+
Sbjct: 1160 EQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQ 1219
Query: 88 GENEQLKISADLIKEKLKSHEQ---EYKNNIAKLVSEMKIKEEGYKKEI------SKLYQ 138
G+ + +K + + ++Q E + +I + +++ KI EE K + S LY
Sbjct: 1220 GQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYN 1279
Query: 139 DMQRKVELNEE-KHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTK 197
+ + +E + + +E K + E +LRS+ +E E + E + + R Q +
Sbjct: 1280 KEMECLRMTDEVERTQTLESKAFQEKE---QLRSKLEEMYEERERTSQEME--MLRKQVE 1334
Query: 198 SKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNT 233
+ ++ ++ +K+Q+ K + + + T
Sbjct: 1335 CLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEET 1370
Score = 34.7 bits (78), Expect = 0.082
Identities = 41/183 (22%), Positives = 82/183 (44%), Gaps = 22/183 (12%)
Query: 44 QLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEK 103
+L K L++ +Q K KEE N + +E+ + E+ Q K
Sbjct: 1092 ELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQ--------SPK 1143
Query: 104 LKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEIS 163
H ++ ++AKL+ + + E + + L + + E E K+ E++ KE
Sbjct: 1144 TPPH---FQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLRE 1200
Query: 164 ELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEK 223
N +L SQ+ ++N +++ QL+ D K + + +++ D+ ++L++ QEE
Sbjct: 1201 MENLRLESQQLIEKNWLLQGQLD-DIKRQK-ENSDQNHPDN---------QQLKNEQEES 1249
Query: 224 NKE 226
KE
Sbjct: 1250 IKE 1252
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 52.4 bits (124), Expect = 4e-07
Identities = 57/252 (22%), Positives = 106/252 (42%), Gaps = 32/252 (12%)
Query: 17 LDKLINDFSQIEKKMVETNGKNNILDIQLE-KSNCLLKVMQAKEVSIKEECATLHNIIKG 75
LD LI + + E K+ + G+ L+ L+ K N V KE I + +++
Sbjct: 878 LDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLE- 936
Query: 76 LQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEIS- 134
+ I + QN E ++LK S +++ E LK E + L +E++ E+ + KE+
Sbjct: 937 -MENIMHSQNC--EIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELED 993
Query: 135 ----------------------KLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQ 172
+L ++ Q+ + +E H E+I++KE ++ EL K+
Sbjct: 994 TLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKV--- 1050
Query: 173 EKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRN 232
+ + KL++E K A ++S + + L+ E EI+ L
Sbjct: 1051 -SDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQ 1109
Query: 233 TIRDLEQRLSVG 244
I+D + VG
Sbjct: 1110 KIQDNNENYQVG 1121
Score = 47.4 bits (111), Expect = 1e-05
Identities = 52/224 (23%), Positives = 96/224 (42%), Gaps = 18/224 (8%)
Query: 9 MKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQL------EKSNCLLKVMQAKEVSI 62
+K + + L + S++ +K+ + N + +L EK C+ +++ E
Sbjct: 1089 LKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEES 1148
Query: 63 KEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEM 122
A L+ + Q E ++NLK + +L+ D +L + E++ I +
Sbjct: 1149 NILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLD---SELSALERQKDEKITQ----- 1200
Query: 123 KIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIK 182
+EE Y+ I L +D Q+ V E+ ++LI+K E E + +E + + E+++
Sbjct: 1201 --QEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEA-IQTALKEFKLEREVVE 1257
Query: 183 LQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQH-FQEEKNK 225
+L K Q DST S +LQ QEEK K
Sbjct: 1258 KELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAK 1301
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 52.4 bits (124), Expect = 4e-07
Identities = 57/252 (22%), Positives = 106/252 (42%), Gaps = 32/252 (12%)
Query: 17 LDKLINDFSQIEKKMVETNGKNNILDIQLE-KSNCLLKVMQAKEVSIKEECATLHNIIKG 75
LD LI + + E K+ + G+ L+ L+ K N V KE I + +++
Sbjct: 878 LDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLE- 936
Query: 76 LQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEIS- 134
+ I + QN E ++LK S +++ E LK E + L +E++ E+ + KE+
Sbjct: 937 -MENIMHSQNC--EIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELED 993
Query: 135 ----------------------KLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQ 172
+L ++ Q+ + +E H E+I++KE ++ EL K+
Sbjct: 994 TLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKV--- 1050
Query: 173 EKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRN 232
+ + KL++E K A ++S + + L+ E EI+ L
Sbjct: 1051 -SDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQ 1109
Query: 233 TIRDLEQRLSVG 244
I+D + VG
Sbjct: 1110 KIQDNNENYQVG 1121
Score = 47.4 bits (111), Expect = 1e-05
Identities = 52/224 (23%), Positives = 96/224 (42%), Gaps = 18/224 (8%)
Query: 9 MKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQL------EKSNCLLKVMQAKEVSI 62
+K + + L + S++ +K+ + N + +L EK C+ +++ E
Sbjct: 1089 LKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEES 1148
Query: 63 KEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEM 122
A L+ + Q E ++NLK + +L+ D +L + E++ I +
Sbjct: 1149 NILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLD---SELSALERQKDEKITQ----- 1200
Query: 123 KIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIK 182
+EE Y+ I L +D Q+ V E+ ++LI+K E E + +E + + E+++
Sbjct: 1201 --QEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEA-IQTALKEFKLEREVVE 1257
Query: 183 LQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQH-FQEEKNK 225
+L K Q DST S +LQ QEEK K
Sbjct: 1258 KELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAK 1301
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 52.4 bits (124), Expect = 4e-07
Identities = 64/254 (25%), Positives = 116/254 (45%), Gaps = 35/254 (13%)
Query: 11 KISSVNLDKLINDFSQIEKKMVETN-GKNNILDIQLEKSNCLLKVMQAKEVSIKEECATL 69
K V + L N+ +++ +K+ ET + N +I +K L + + AK+ I+ + +
Sbjct: 248 KYKDVIIANLQNEVAELSQKVSETTTSRQNEKEIS-QKCQVLDEDIDAKQKEIQSLKSQI 306
Query: 70 HNIIKG----LQQTIEYQQN----LKGENEQLK--------ISADLIKEKLKSHEQ--EY 111
+ KG L QT+ + + LK E E LK + + L K+ L EQ +
Sbjct: 307 SALQKGYSKVLCQTLSERNSEITSLKNEGENLKRDNAITSGMVSSLQKDILAKDEQVQQL 366
Query: 112 KNNIAKLVSEMKIKE---EGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAK 168
K ++ L S+ K K+ E S L +++++ E+ H+EL E +E E+ +
Sbjct: 367 KEEVSHLKSQNKDKDHQLEALGSRCSVLKEELKQ-----EDAHRELREAQEKELKLCKTQ 421
Query: 169 LRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIY---RRKLQHFQEEKNK 225
++ EKE + KL+ E S++ ++ + + + + RRKL QE N+
Sbjct: 422 IQDMEKEMK----KLRAELRKSCTEQSVISRTLREKSKVEEKLQEDSRRKLLQLQEMGNR 477
Query: 226 EIAILRNTIRDLEQ 239
E I N R + Q
Sbjct: 478 ESVIKINLERAVGQ 491
Score = 45.4 bits (106), Expect = 5e-05
Identities = 38/163 (23%), Positives = 79/163 (48%), Gaps = 12/163 (7%)
Query: 19 KLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSI-KEECATLHNIIKGLQ 77
KL D ++ +M + G+ N + N +L Q+KE+S+ KE+ A + ++++
Sbjct: 1013 KLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVLKEKMAQMSSLVE--- 1069
Query: 78 QTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLY 137
+ + LK E L+ S + + +L + E+E K + ++ E E
Sbjct: 1070 ---KKDRELKALEEALRASQEKHRLQLNT-EKEQKPRKKTQTCDTSVQIEPVHTEAFSSS 1125
Query: 138 QDMQRKVELNEE----KHKELIEKKEMEISELNAKLRSQEKEK 176
Q+ Q +L +H+E+I++++ +SEL A+++ EK +
Sbjct: 1126 QEQQSFSDLGVRCKGSRHEEVIQRQKKALSELRARIKELEKAR 1168
Score = 39.3 bits (90), Expect = 0.003
Identities = 38/186 (20%), Positives = 90/186 (48%), Gaps = 15/186 (8%)
Query: 53 KVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKL-------- 104
++M+ KE IK+ T+ ++ + LQ+ ++ + ++GE LK + KE+
Sbjct: 921 EIMEYKE-QIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAP 979
Query: 105 ----KSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEM 160
+ + Y++ I L++ K + ++ I KL +D+ + EL EK++M
Sbjct: 980 MTESSAKDMAYEHLIDDLLAAQK-EILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKM 1038
Query: 161 EISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQ 220
E+ E N L Q+ ++ + + + + + + + + K+ +++ Q +R +L +
Sbjct: 1039 EL-EQNVVLVQQQSKELSVLKEKMAQMSSLVEKKDRELKALEEALRASQEKHRLQLNTEK 1097
Query: 221 EEKNKE 226
E+K ++
Sbjct: 1098 EQKPRK 1103
Score = 33.9 bits (76), Expect = 0.14
Identities = 18/107 (16%), Positives = 46/107 (42%)
Query: 140 MQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSK 199
++ + + KE +E++ + EL + L Q+K I + + L QT+ +
Sbjct: 690 LEEYITQERNRAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQ 749
Query: 200 SYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKD 246
++ + + + H + + + + + ++DLE L+ K+
Sbjct: 750 ELEERLARQKEVLESSIAHEKRKAKEALESEKRKVQDLENHLTQQKE 796
Score = 32.7 bits (73), Expect = 0.31
Identities = 29/166 (17%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Query: 78 QTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLY 137
Q + ++ K E + + KE L+ + + + L + K + +E +++
Sbjct: 679 QATDGREGGKALEEYITQERNRAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVK 738
Query: 138 QDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTK 197
+ ++ + +E + L +KE+ S + + EK K E ++ + L T+
Sbjct: 739 EALEEEQTRVQELEERLARQKEVLESSI-----AHEKRKAKEALESEKRKVQDLENHLTQ 793
Query: 198 SKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSV 243
K +S + + +RK + E++ K++ L N + ++ L +
Sbjct: 794 QKEISESNI---AYEKRKAKEAMEKEKKKVQDLENRLTKQKEELEL 836
Score = 30.4 bits (67), Expect = 1.6
Identities = 37/169 (21%), Positives = 75/169 (44%), Gaps = 29/169 (17%)
Query: 100 IKEKLKSHE---QEYKNNIAK---------LVSEMKIKE--EGYKKEISKLYQDMQRKVE 145
+KE L+ + QE + +A+ + K KE E K+++ L + ++ E
Sbjct: 737 VKEALEEEQTRVQELEERLARQKEVLESSIAHEKRKAKEALESEKRKVQDLENHLTQQKE 796
Query: 146 LNE-------EKHKELIEKKEMEISELNAKLRSQEKE---KQNEIIKLQLEFDAKLARVQ 195
++E K KE +EK++ ++ +L +L Q++E K+ + L + LA V+
Sbjct: 797 ISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVE 856
Query: 196 TKSKSYQDSTVLPQSI---YRRKLQHFQEEKNKEIAILRNTIRDLEQRL 241
K+ ++ +S+ L + K K I + I L+Q++
Sbjct: 857 ETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLI--LQQKM 903
>gi|38348729 hypothetical protein LOC203238 [Homo sapiens]
Length = 1326
Score = 52.4 bits (124), Expect = 4e-07
Identities = 57/217 (26%), Positives = 96/217 (44%), Gaps = 37/217 (17%)
Query: 47 KSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTI-----EYQQNLKGENEQLKISADLIK 101
K+N K Q + KEEC + ++ I EY +K E +L+ +
Sbjct: 126 KTNETEKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMK-EKSRLEKTLQEAL 184
Query: 102 EKLKSHEQEYKNNIAKL-VSEMKIKEEGYKKEISKLY----------QDMQRKVELNEEK 150
EK + + E +++I + + E +++EE ++ E +L Q+M +KVE E +
Sbjct: 185 EKHQREKNEMESHIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETE 244
Query: 151 HKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQS 210
H + + + SEL + +E +L+ EF+A RV+ L ++
Sbjct: 245 HMDCSDLLRRQTSELEFSTQREE--------RLRKEFEATTLRVRK----------LEEN 286
Query: 211 IYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDS 247
I + H + + N EI LR IRDLE L V K S
Sbjct: 287 IEAERAAHLESKFNSEIIQLR--IRDLEGALQVEKAS 321
Score = 35.0 bits (79), Expect = 0.063
Identities = 52/287 (18%), Positives = 120/287 (41%), Gaps = 49/287 (17%)
Query: 11 KISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLH 70
KI+S+++ +++ + ++++ + N + + + EK K A+ S + + A L
Sbjct: 16 KIASLDVKQILKNETELD---ITDNLRKKLHWAKKEKLEITTK-HNAELASYESQIAKLR 71
Query: 71 NIIK---GLQQTIEYQQNLKGEN--------EQLKISADLIKEKLKSHEQEYKNNIAKLV 119
+ ++ L+Q++EY + + E+ A I+EKL + E + +
Sbjct: 72 SEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETE 131
Query: 120 SEMKIKEEGYKKEISKLYQDMQRKVE-----------LNEEKHK------ELIEKKEMEI 162
+ ++ +K+E + D++ + L +EK + E +EK + E
Sbjct: 132 KAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREK 191
Query: 163 SELNAKLRS--------QEKEKQNEIIKLQL---EFDAKLARVQTKSKSYQDSTVLPQSI 211
+E+ + +R QE++ + E +LQ E D + + K + + + +
Sbjct: 192 NEMESHIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDL 251
Query: 212 YRRKLQHF------QEEKNKEIAILRNTIRDLEQRLSVGKDSHLKRR 252
RR+ +E KE +R LE+ + + +HL+ +
Sbjct: 252 LRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESK 298
Score = 32.3 bits (72), Expect = 0.41
Identities = 41/199 (20%), Positives = 87/199 (43%), Gaps = 34/199 (17%)
Query: 77 QQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKL 136
+ T Q+ + G ++L +A++ + L+ E+K ++ ++ E+ K +G + ++++
Sbjct: 967 KSTASLQKQILGFTQRLH-AAEVERRSLRLEVTEFKRSVNEMKKELD-KAQGLQMQLNEF 1024
Query: 137 YQDM---QRKVE----------LNEEKHKELIEKKEMEISELNAKLR---SQEKEKQ--- 177
Q K E L EE+ + L+ ++ ++ ELN KL S+E +K
Sbjct: 1025 KQSKLITHEKFESACEELNNALLREEQAQMLLNEQAQQLQELNYKLELHSSEEADKNQTL 1084
Query: 178 NEIIKLQLEFDAKLARVQTKSKSY--------QDSTVLPQSIYRRKLQHFQEEKNKE--- 226
E +K E +L R + QD L ++I+ + K+KE
Sbjct: 1085 GEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVA 1144
Query: 227 --IAILRNTIRDLEQRLSV 243
+ + NT+ + ++S+
Sbjct: 1145 NHMRAVENTLHKVRDQISL 1163
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.0 bits (123), Expect = 5e-07
Identities = 53/231 (22%), Positives = 111/231 (48%), Gaps = 28/231 (12%)
Query: 15 VNLDKLINDFSQIEKKM---VETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEE----CA 67
V D+L + + K+ VE N N+L+ Q E+ M +E I+E+ C
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEK------MWRQEEKIQEQEEKMCE 315
Query: 68 TLHNIIKGLQQTIEYQQNLKGENEQLKISADLI---KEKLKSHEQEYKNNIAKLV-SEMK 123
I + ++ ++ + + E+++ D + +EK++ E++ + K+ E K
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 124 IKEEGYKKEISKLYQDMQR---KVELNEEKHKELIEKKEMEISELNAKLRSQE------K 174
I+E+ K I + ++M R K+ EEK +E + ++E ++ E + K+R QE +
Sbjct: 376 IREQDEK--IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 175 EKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNK 225
EK E+ ++ + + KL V+ K + ++ + +R+ + QE++ K
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Score = 40.8 bits (94), Expect = 0.001
Identities = 30/148 (20%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Query: 81 EYQQNLKGENEQLKISADLIKE---KLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLY 137
E ++ ++ + E++ + I+E K++ E+E K+ + + ++E ++ K+
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 138 QDMQRKVELNEE--KHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQ 195
+ ++ E EE + +E I + E + + KLR E++ Q E K+Q E + K+ R +
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ-EQEEKIQRQE 475
Query: 196 TKSKSYQDSTVLPQSIYRRKLQHFQEEK 223
K + ++ T + + +++ + +++E+
Sbjct: 476 EKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Score = 37.7 bits (86), Expect = 0.010
Identities = 31/143 (21%), Positives = 79/143 (55%), Gaps = 12/143 (8%)
Query: 63 KEECATLHNIIKGLQQTI-EYQQNLKGENEQLKISADLIK---EKLKSHEQEYKNNIAKL 118
+E+ L +++ ++ + E ++ ++ E E+++ + I+ EK++ E++ L
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492
Query: 119 VSEMKIKEEGYK--KEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEK 176
E KI E+ K ++ K+++ + K++ EEK ++++E ++ E +L QE++
Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQ-EEKMQEQEEK----MQRQEEKMREQEVRLWQQEEKM 547
Query: 177 QNEIIKLQLEFDAKLARVQTKSK 199
Q + ++LQ E + +L ++ K++
Sbjct: 548 QEQEVRLQ-ELEERLGKLGQKAE 569
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.0 bits (123), Expect = 5e-07
Identities = 53/231 (22%), Positives = 111/231 (48%), Gaps = 28/231 (12%)
Query: 15 VNLDKLINDFSQIEKKM---VETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEE----CA 67
V D+L + + K+ VE N N+L+ Q E+ M +E I+E+ C
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEK------MWRQEEKIQEQEEKMCE 315
Query: 68 TLHNIIKGLQQTIEYQQNLKGENEQLKISADLI---KEKLKSHEQEYKNNIAKLV-SEMK 123
I + ++ ++ + + E+++ D + +EK++ E++ + K+ E K
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 124 IKEEGYKKEISKLYQDMQR---KVELNEEKHKELIEKKEMEISELNAKLRSQE------K 174
I+E+ K I + ++M R K+ EEK +E + ++E ++ E + K+R QE +
Sbjct: 376 IREQDEK--IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 175 EKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNK 225
EK E+ ++ + + KL V+ K + ++ + +R+ + QE++ K
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Score = 40.8 bits (94), Expect = 0.001
Identities = 30/148 (20%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Query: 81 EYQQNLKGENEQLKISADLIKE---KLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLY 137
E ++ ++ + E++ + I+E K++ E+E K+ + + ++E ++ K+
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 138 QDMQRKVELNEE--KHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQ 195
+ ++ E EE + +E I + E + + KLR E++ Q E K+Q E + K+ R +
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ-EQEEKIQRQE 475
Query: 196 TKSKSYQDSTVLPQSIYRRKLQHFQEEK 223
K + ++ T + + +++ + +++E+
Sbjct: 476 EKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Score = 37.7 bits (86), Expect = 0.010
Identities = 31/143 (21%), Positives = 79/143 (55%), Gaps = 12/143 (8%)
Query: 63 KEECATLHNIIKGLQQTI-EYQQNLKGENEQLKISADLIK---EKLKSHEQEYKNNIAKL 118
+E+ L +++ ++ + E ++ ++ E E+++ + I+ EK++ E++ L
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492
Query: 119 VSEMKIKEEGYK--KEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEK 176
E KI E+ K ++ K+++ + K++ EEK ++++E ++ E +L QE++
Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQ-EEKMQEQEEK----MQRQEEKMREQEVRLWQQEEKM 547
Query: 177 QNEIIKLQLEFDAKLARVQTKSK 199
Q + ++LQ E + +L ++ K++
Sbjct: 548 QEQEVRLQ-ELEERLGKLGQKAE 569
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 52.0 bits (123), Expect = 5e-07
Identities = 58/208 (27%), Positives = 105/208 (50%), Gaps = 44/208 (21%)
Query: 73 IKGLQQTIEYQQNLKGENEQL--------KISADLIKEKLKSHEQ--EYKNNIAKLVS-- 120
+K L Q ++ L+ ++E+L K+ +L +E + H+Q E KN +A+ +
Sbjct: 841 VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGEL-EEMERKHQQLLEEKNILAEQLQAE 899
Query: 121 --------EMKIKEEGYKKEISKLYQDMQRKVELNEEKHKEL-IEKKEME--ISELNAKL 169
EM+ + K+E+ ++ D++ +VE EE+++ L EKK+M+ I +L +L
Sbjct: 900 TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 170 RSQEKEKQNEIIKLQLE---FDAKLARVQTK--------SKSYQDSTVLPQSIYRRKLQ- 217
+E +Q KLQLE +AK+ +++ + SK ++ ++ I Q
Sbjct: 960 DEEEGARQ----KLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL 1015
Query: 218 HFQEEKNKEIAILRN----TIRDLEQRL 241
+EEK K +A +RN I DLE+RL
Sbjct: 1016 AEEEEKAKNLAKIRNKQEVMISDLEERL 1043
Score = 51.6 bits (122), Expect = 7e-07
Identities = 55/232 (23%), Positives = 119/232 (51%), Gaps = 23/232 (9%)
Query: 19 KLINDFSQIEKKMVETNGKNNILDIQLEKSNCLL---KVMQAKEVSIKEEC-ATLHNIIK 74
K+ + ++E+K + + NIL QL+ L + M+A+ + K+E LH++
Sbjct: 870 KVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLES 929
Query: 75 GLQQTIEYQQNLKGENEQLKISADLIKEKLKSHE-QEYKNNIAKLVSEMKIKEEGYKKEI 133
+++ E Q L+ E ++++ ++E+L E K + K+ +E KIK+
Sbjct: 930 RVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKK------- 982
Query: 134 SKLYQDMQRKVELNEEKHKELI-EKKEME--ISELNAKLRSQEKEKQNEIIKLQLEFDAK 190
M+ ++ L E+++ + I EKK ME I+E +++L ++E+EK + K++ + +
Sbjct: 983 ------MEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL-AEEEEKAKNLAKIRNKQEVM 1035
Query: 191 LARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLS 242
++ ++ + K ++ T +RKL + +IA L+ I +L+ +L+
Sbjct: 1036 ISDLEERLKK-EEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLA 1086
Score = 44.7 bits (104), Expect = 8e-05
Identities = 51/239 (21%), Positives = 108/239 (45%), Gaps = 35/239 (14%)
Query: 14 SVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNII 73
+V+LD S +EKK + + +L + S + E +E+ ++
Sbjct: 1433 TVDLDHQRQVASNLEKKQKKFD---QLLAEEKSISARYAEERDRAEAEAREKETKALSLA 1489
Query: 74 KGLQQTIEYQQNLKGENEQLKISA-DLIKEK----------------LKSHEQEYKNNIA 116
+ L++ +E ++ + +N+QL+ DL+ K L+ +E + +
Sbjct: 1490 RALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLE 1549
Query: 117 KLVSEMKIKEEG-YKKEIS------KLYQDMQRKVELNEEKHKELIEKKEMEISELNAKL 169
+L E++ E+ + E++ + +D+Q + E NEEK + LI+ ++ EL A+L
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK----QVRELEAEL 1605
Query: 170 RSQEKEKQNEII-KLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEI 227
+ K++ + K ++E D K Q ++ + V+ Q RKLQ ++ +E+
Sbjct: 1606 EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ---LRKLQAQMKDYQREL 1661
Score = 42.0 bits (97), Expect = 5e-04
Identities = 39/209 (18%), Positives = 94/209 (44%), Gaps = 9/209 (4%)
Query: 42 DIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIK 101
+++ ++ + ++ +A E K A + ++ + +E + ++ K + + K
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
Query: 102 EKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKK--- 158
+ L++ +E + K++ ++K + E +K++ Q++ KV + EL EK
Sbjct: 1227 QGLETDNKELACEV-KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKL 1285
Query: 159 EMEISELNAKLRSQEKE-----KQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYR 213
+ E+ ++ L EK+ K ++ QL+ +L + +T+ K S + +
Sbjct: 1286 QNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEK 1345
Query: 214 RKLQHFQEEKNKEIAILRNTIRDLEQRLS 242
LQ QEE+ + L + L+ +L+
Sbjct: 1346 NSLQEQQEEEEEARKNLEKQVLALQSQLA 1374
Score = 34.3 bits (77), Expect = 0.11
Identities = 38/183 (20%), Positives = 85/183 (46%), Gaps = 32/183 (17%)
Query: 25 SQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQ 84
+Q+E+++ E +L+ + K+ + + A E++ + A Q++ +Q
Sbjct: 1739 AQLEEELEEEQSNMELLNDRFRKTTLQVDTLNA-ELAAERSAA---------QKSDNARQ 1788
Query: 85 NLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEI------SKLYQ 138
L+ +N++LK ++ +KS ++K I+ L +++ EE ++E +KL +
Sbjct: 1789 QLERQNKELKAKLQELEGAVKS---KFKATISALEAKIGQLEEQLEQEAKERAAANKLVR 1845
Query: 139 DMQRKVE----------LNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEII---KLQL 185
++K++ + +++KE +EK + +L +L E+E KLQ
Sbjct: 1846 RTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQR 1905
Query: 186 EFD 188
E D
Sbjct: 1906 ELD 1908
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 52.0 bits (123), Expect = 5e-07
Identities = 61/243 (25%), Positives = 107/243 (44%), Gaps = 41/243 (16%)
Query: 46 EKSNCLLKVMQAKEVS----IKE-ECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLI 100
+ ++ L K + K+V IKE E L + GL+ T E + LK + E ADL+
Sbjct: 670 QAASILTKFQELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLL 729
Query: 101 KEKLKS---HEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEK 157
+ KL+ H+Q+ + + K E + E K ++ + + K E+ E K K +
Sbjct: 730 QTKLQQSSYHKQQEELDALKKTIE---ESEETLKNTKEIQRKAEEKYEVLENKMKNAEAE 786
Query: 158 KEMEISELNAKL------------RSQEKEKQNEIIKLQLE--------FDAKLARVQTK 197
+E E+ + KL + +EK+++ E I L+LE + +L V
Sbjct: 787 RERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEA 846
Query: 198 SKSYQDS-TVLPQSIYRRK--LQHFQEE--KNKEIAILRNTI-----RDLEQRLSVGKDS 247
KSY+ V+ + + K + QEE K KE+ ++T+ ++ + DS
Sbjct: 847 IKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDS 906
Query: 248 HLK 250
LK
Sbjct: 907 QLK 909
Score = 40.8 bits (94), Expect = 0.001
Identities = 47/191 (24%), Positives = 79/191 (41%), Gaps = 23/191 (12%)
Query: 20 LINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQT 79
++ D + K E + L E SN + + A + A L + G + T
Sbjct: 338 MVEDSKTLAAKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEAT 397
Query: 80 IEYQQNL-KGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQ 138
+ Q K + + + A + KLK +QE KN A E+K + GY+K+ L
Sbjct: 398 LAGQMMACKNDISKAQTEAKQAQMKLKHAQQELKNKQA----EVKKMDSGYRKDQEAL-- 451
Query: 139 DMQRKVELNEEKHKELIEKKEMEISELNAKLRSQE------KEKQNEIIKLQLEFDAKLA 192
E K L EK E E+ +LN + +E ++ +I +L+ ++A LA
Sbjct: 452 ----------EAVKRLKEKLEAEMKKLNYEENKEESLLEKRRQLSRDIGRLKETYEALLA 501
Query: 193 RVQTKSKSYQD 203
R +Y+D
Sbjct: 502 RFPNLRFAYKD 512
Score = 31.6 bits (70), Expect = 0.70
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 14/110 (12%)
Query: 141 QRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARV------ 194
Q+ +E E K KE+ E EI+ KL+ +E+ E K+ E + L+R+
Sbjct: 182 QKTIEKKEAKLKEIKTILEEEITPTIQKLK-EERSSYLEYQKVMREIE-HLSRLYIAYQF 239
Query: 195 ----QTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQR 240
TK +S ++ + + KLQ E +K+I L + I +LE+R
Sbjct: 240 LLAEDTKVRSAEELKEMQDKVI--KLQEELSENDKKIKALNHEIEELEKR 287
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 52.0 bits (123), Expect = 5e-07
Identities = 61/243 (25%), Positives = 107/243 (44%), Gaps = 41/243 (16%)
Query: 46 EKSNCLLKVMQAKEVS----IKE-ECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLI 100
+ ++ L K + K+V IKE E L + GL+ T E + LK + E ADL+
Sbjct: 670 QAASILTKFQELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLL 729
Query: 101 KEKLKS---HEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEK 157
+ KL+ H+Q+ + + K E + E K ++ + + K E+ E K K +
Sbjct: 730 QTKLQQSSYHKQQEELDALKKTIE---ESEETLKNTKEIQRKAEEKYEVLENKMKNAEAE 786
Query: 158 KEMEISELNAKL------------RSQEKEKQNEIIKLQLE--------FDAKLARVQTK 197
+E E+ + KL + +EK+++ E I L+LE + +L V
Sbjct: 787 RERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEA 846
Query: 198 SKSYQDS-TVLPQSIYRRK--LQHFQEE--KNKEIAILRNTI-----RDLEQRLSVGKDS 247
KSY+ V+ + + K + QEE K KE+ ++T+ ++ + DS
Sbjct: 847 IKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDS 906
Query: 248 HLK 250
LK
Sbjct: 907 QLK 909
Score = 40.8 bits (94), Expect = 0.001
Identities = 47/191 (24%), Positives = 79/191 (41%), Gaps = 23/191 (12%)
Query: 20 LINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQT 79
++ D + K E + L E SN + + A + A L + G + T
Sbjct: 338 MVEDSKTLAAKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEAT 397
Query: 80 IEYQQNL-KGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQ 138
+ Q K + + + A + KLK +QE KN A E+K + GY+K+ L
Sbjct: 398 LAGQMMACKNDISKAQTEAKQAQMKLKHAQQELKNKQA----EVKKMDSGYRKDQEAL-- 451
Query: 139 DMQRKVELNEEKHKELIEKKEMEISELNAKLRSQE------KEKQNEIIKLQLEFDAKLA 192
E K L EK E E+ +LN + +E ++ +I +L+ ++A LA
Sbjct: 452 ----------EAVKRLKEKLEAEMKKLNYEENKEESLLEKRRQLSRDIGRLKETYEALLA 501
Query: 193 RVQTKSKSYQD 203
R +Y+D
Sbjct: 502 RFPNLRFAYKD 512
Score = 31.6 bits (70), Expect = 0.70
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 14/110 (12%)
Query: 141 QRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARV------ 194
Q+ +E E K KE+ E EI+ KL+ +E+ E K+ E + L+R+
Sbjct: 182 QKTIEKKEAKLKEIKTILEEEITPTIQKLK-EERSSYLEYQKVMREIE-HLSRLYIAYQF 239
Query: 195 ----QTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQR 240
TK +S ++ + + KLQ E +K+I L + I +LE+R
Sbjct: 240 LLAEDTKVRSAEELKEMQDKVI--KLQEELSENDKKIKALNHEIEELEKR 287
>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 52.0 bits (123), Expect = 5e-07
Identities = 61/243 (25%), Positives = 107/243 (44%), Gaps = 41/243 (16%)
Query: 46 EKSNCLLKVMQAKEVS----IKE-ECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLI 100
+ ++ L K + K+V IKE E L + GL+ T E + LK + E ADL+
Sbjct: 670 QAASILTKFQELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLL 729
Query: 101 KEKLKS---HEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEK 157
+ KL+ H+Q+ + + K E + E K ++ + + K E+ E K K +
Sbjct: 730 QTKLQQSSYHKQQEELDALKKTIE---ESEETLKNTKEIQRKAEEKYEVLENKMKNAEAE 786
Query: 158 KEMEISELNAKL------------RSQEKEKQNEIIKLQLE--------FDAKLARVQTK 197
+E E+ + KL + +EK+++ E I L+LE + +L V
Sbjct: 787 RERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEA 846
Query: 198 SKSYQDS-TVLPQSIYRRK--LQHFQEE--KNKEIAILRNTI-----RDLEQRLSVGKDS 247
KSY+ V+ + + K + QEE K KE+ ++T+ ++ + DS
Sbjct: 847 IKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDS 906
Query: 248 HLK 250
LK
Sbjct: 907 QLK 909
Score = 40.8 bits (94), Expect = 0.001
Identities = 47/191 (24%), Positives = 79/191 (41%), Gaps = 23/191 (12%)
Query: 20 LINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQT 79
++ D + K E + L E SN + + A + A L + G + T
Sbjct: 338 MVEDSKTLAAKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEAT 397
Query: 80 IEYQQNL-KGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQ 138
+ Q K + + + A + KLK +QE KN A E+K + GY+K+ L
Sbjct: 398 LAGQMMACKNDISKAQTEAKQAQMKLKHAQQELKNKQA----EVKKMDSGYRKDQEAL-- 451
Query: 139 DMQRKVELNEEKHKELIEKKEMEISELNAKLRSQE------KEKQNEIIKLQLEFDAKLA 192
E K L EK E E+ +LN + +E ++ +I +L+ ++A LA
Sbjct: 452 ----------EAVKRLKEKLEAEMKKLNYEENKEESLLEKRRQLSRDIGRLKETYEALLA 501
Query: 193 RVQTKSKSYQD 203
R +Y+D
Sbjct: 502 RFPNLRFAYKD 512
Score = 31.6 bits (70), Expect = 0.70
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 14/110 (12%)
Query: 141 QRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARV------ 194
Q+ +E E K KE+ E EI+ KL+ +E+ E K+ E + L+R+
Sbjct: 182 QKTIEKKEAKLKEIKTILEEEITPTIQKLK-EERSSYLEYQKVMREIE-HLSRLYIAYQF 239
Query: 195 ----QTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQR 240
TK +S ++ + + KLQ E +K+I L + I +LE+R
Sbjct: 240 LLAEDTKVRSAEELKEMQDKVI--KLQEELSENDKKIKALNHEIEELEKR 287
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 51.2 bits (121), Expect = 9e-07
Identities = 63/266 (23%), Positives = 122/266 (45%), Gaps = 38/266 (14%)
Query: 14 SVNLDKLINDFSQIEKKMVETNGKNNILDI-QLEKSNCL--LKVMQAKEVSIKEECATLH 70
SV ++ + S + K+ +T +NI+ + + EK L L+ + A++ +++E+ +
Sbjct: 537 SVLYNEAQEELSALRKESTQTTAPHNIVSLMEKEKELALSDLRRIMAEKEALREKLEHIE 596
Query: 71 NII----KGLQQTIEY----QQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEM 122
+ L++TIE+ L+ E +LK ++KE ++S E + K K S +
Sbjct: 597 EVSLFGKSELEKTIEHLTCVNHQLESEKYELKSKVLIMKETIESLENKLKVQAQKF-SHV 655
Query: 123 KIKEEGYKKEISKLY---QDMQRKVELNEEKHKELIEKKEME------------ISELNA 167
K E++ L + +QR V+ + +H+ I++ E+E I ELN
Sbjct: 656 AGDSSHQKTEVNSLRIVNEQLQRSVD--DYQHRLSIKRGELESAQAQIKILEEKIDELNL 713
Query: 168 KLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEI 227
K+ SQ++E ++K K V K K + TV ++ LQ K K +
Sbjct: 714 KMTSQDEEA--HVMK-------KTIGVIDKEKDFLQETVDEKTEKIANLQENLANKEKAV 764
Query: 228 AILRNTIRDLEQRLSVGKDSHLKRRR 253
A ++ I + E ++ K++ + R R
Sbjct: 765 AQMKIMISECESSVNQLKETLVNRDR 790
Score = 37.0 bits (84), Expect = 0.017
Identities = 43/226 (19%), Positives = 104/226 (46%), Gaps = 19/226 (8%)
Query: 25 SQIEKKMVETNGKNNILDIQLEKSNCLL-KVMQAKEVSIKEECATLHNIIKGLQQTIEYQ 83
+Q+++ +V + + N L QL+ ++ L +V +++E++ KE + LQ +
Sbjct: 779 NQLKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKEN--------RRLQDDLA-- 828
Query: 84 QNLKGENEQLKISADLI---KEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDM 140
+ EN+++ + + KE++KS +Y +++ S M KE+ + + +
Sbjct: 829 -TMARENQEISLELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENQDLLDRFQMLH 887
Query: 141 QRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKS 200
R + + H+ E + + L+ + ++ E+++ +++ + +S
Sbjct: 888 NRAEDWEVKAHQAEGESSSVRLELLSIDTERRHLRERVELLEKEIQ---EHINAHHAYES 944
Query: 201 YQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKD 246
S S +L+H ++EK + L +++R+L +L GKD
Sbjct: 945 QISSMAKAMSRLEEELRHQEDEKATVLNDL-SSLRELCIKLDSGKD 989
Score = 31.2 bits (69), Expect = 0.91
Identities = 37/163 (22%), Positives = 73/163 (44%), Gaps = 31/163 (19%)
Query: 85 NLKGENEQL---KISADLIKEKLKSHEQEY-----------KNNIAKLVSEMKIKEEGYK 130
NL +NE+L D + ++L+ H++E K I + +SEM+ EE
Sbjct: 307 NLSNKNEKLCQELTEIDQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMA 366
Query: 131 KEISKLYQDMQRKVELNEE-----KHKELIEKKEMEISELNAKLRS---QEKEKQNEIIK 182
K +L + K L++E + ++ + E E L+ K+ S E++ E+ +
Sbjct: 367 KLQLELNLCQKEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVER 426
Query: 183 LQLEF-----DAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQ 220
++LE D +R+ T K ++ + Y+++L+ Q
Sbjct: 427 MRLEHGIKRRDRSPSRLDTFLKGIEEE----RDYYKKELERLQ 465
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 51.2 bits (121), Expect = 9e-07
Identities = 49/190 (25%), Positives = 95/190 (50%), Gaps = 25/190 (13%)
Query: 46 EKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISAD------- 98
EK + L + ++A E E L + L Q +E+++ + E K+ D
Sbjct: 2033 EKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAA 2092
Query: 99 -LIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEK 157
++ + LK ++E ++N + S+MK K+E D++R++E EEKH L EK
Sbjct: 2093 RVLADNLKL-KKELQSNKESVKSQMKQKDE-----------DLERRLEQAEEKH--LKEK 2138
Query: 158 KEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQ 217
K M+ +L+A LR ++ + I ++Q+ + K VQ ++ DSTV + + + +
Sbjct: 2139 KNMQ-EKLDA-LRREKVHLEETIGEIQVTLNKKDKEVQQLQENL-DSTVTQLAAFTKSMS 2195
Query: 218 HFQEEKNKEI 227
Q+++++ I
Sbjct: 2196 SLQDDRDRVI 2205
Score = 47.4 bits (111), Expect = 1e-05
Identities = 54/245 (22%), Positives = 112/245 (45%), Gaps = 38/245 (15%)
Query: 18 DKLINDFSQIE-------KKMVETNGKNNILDIQLEK-SNCLLKVMQAKEVSIKEECATL 69
++L+N +++ + + + KN +L+ +++ C+ ++ + K+ +KE+
Sbjct: 1924 ERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1983
Query: 70 HNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGY 129
I K + I+ Q G K +L+KEK + +Q K+ I Y
Sbjct: 1984 SEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR------------Y 2031
Query: 130 KKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELN-AKLRSQEKEKQNEIIKLQLEFD 188
+++IS L +R V+ E E +K++EI++ N A+ K+ Q E+ ++ D
Sbjct: 2032 QEKISAL----ERTVKALEFVQTE--SQKDLEITKENLAQAVEHRKKAQAELASFKVLLD 2085
Query: 189 AKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSH 248
T+S++ + VL ++ +K Q K + ++ DLE+RL ++ H
Sbjct: 2086 ------DTQSEA---ARVLADNLKLKK--ELQSNKESVKSQMKQKDEDLERRLEQAEEKH 2134
Query: 249 LKRRR 253
LK ++
Sbjct: 2135 LKEKK 2139
Score = 46.2 bits (108), Expect = 3e-05
Identities = 46/210 (21%), Positives = 102/210 (48%), Gaps = 26/210 (12%)
Query: 18 DKLINDFS-QIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGL 76
D+ + + S + +KMV+ N + L ++++ L ++ E + KE+ + + GL
Sbjct: 900 DQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGL 959
Query: 77 QQTIEYQQNLKGE--NEQLKISADLIKEKLKSHEQEYKNNIAKLVS--EMKIKEEGYKKE 132
+Q + + + G+ E+L+ DL+K K +EQ + A L++ E+ + ++E
Sbjct: 960 KQNYD-EMSPAGQISKEELQHEFDLLK---KENEQRKRKLQAALINRKELLQRVSRLEEE 1015
Query: 133 ISKLYQDMQRKVELNEEKHKELIEKKE----------MEISELNAKLRSQEKEKQNEIIK 182
++ L + ++++ L+E + E+ E KE + E+ L+ EK+ E+
Sbjct: 1016 LANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQH 1075
Query: 183 LQLEFDAKLAR-------VQTKSKSYQDST 205
++ + + KLA V+ +++ QD T
Sbjct: 1076 IRKDLEEKLAAEEQFQALVKQMNQTLQDKT 1105
Score = 45.4 bits (106), Expect = 5e-05
Identities = 49/240 (20%), Positives = 108/240 (45%), Gaps = 25/240 (10%)
Query: 32 VETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNLKGENE 91
++ + + +L++QL+++ L E +KE ++ + E +Q+L E E
Sbjct: 2546 IKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIE 2605
Query: 92 QLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKH 151
LK+S + ++ + ++E + +++K+KEE + +S L+ Q+++ EE+
Sbjct: 2606 SLKVSISQLTRQVTALQEE--GTLGLYHAQLKVKEEEVHR-LSALFSSSQKRIAELEEEL 2662
Query: 152 KELIEKKEMEISELNAKLRSQEK-----------------EKQNEIIKLQLEFDAKLARV 194
+ ++ ++ E+ KL+ + K E+ E+ + +E + KL V
Sbjct: 2663 VCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2722
Query: 195 QTKSKSYQDSTVLPQSIYR--RKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSHLKRR 252
++K T QS R LQ+ ++ N+E+ L+ + L+ K+ L R
Sbjct: 2723 TKENKGL---TAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNR 2779
Score = 41.2 bits (95), Expect = 9e-04
Identities = 43/196 (21%), Positives = 91/196 (46%), Gaps = 15/196 (7%)
Query: 14 SVNLDKLINDFSQIE--KKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHN 71
S+++++L + S++E K++ E+ + ++QL++ C + KE+ + E T H
Sbjct: 2244 SIHMEELKINISRLEHDKQIWESKAQT---EVQLQQKVCDTLQGENKELLSQLE-ETRHL 2299
Query: 72 IIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKK 131
+ + + LK +QL DL K EQ K N+ ++ + + + K
Sbjct: 2300 YHSSQNELAKLESELKSLKDQL---TDLSNSLEKCKEQ--KGNLEGIIRQQEADIQNSKF 2354
Query: 132 EISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKL 191
+L D+Q EL H+E+ K++ IS L+ K E+ Q I +L+ + D ++
Sbjct: 2355 SYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGK----EEAIQVAIAELRQQHDKEI 2410
Query: 192 ARVQTKSKSYQDSTVL 207
++ ++ ++
Sbjct: 2411 KELENLLSQEEEENIV 2426
Score = 40.4 bits (93), Expect = 0.002
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 44/253 (17%)
Query: 26 QIEKKMVET-NGKNNILDIQLEKSNCL-------LKVMQAKEVSIKEECATLHNIIK--- 74
Q+++K+ +T G+N L QLE++ L L ++++ S+K++ L N ++
Sbjct: 2273 QLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCK 2332
Query: 75 ----GLQQTIEYQ----QNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKE 126
L+ I Q QN K EQL+ +E +E K++S + KE
Sbjct: 2333 EQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKE 2392
Query: 127 EGYKKEISKLYQDMQRKVE--------------LNEEKHKELIEKKE--MEISELNAKLR 170
E + I++L Q ++++ + EE++K+ ++K ME + K
Sbjct: 2393 EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEN 2452
Query: 171 SQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQE---EKNK-- 225
Q+K + + +K R+ YQ SI K Q QE E NK
Sbjct: 2453 IQQKAQLDSFVKSMSSLQNDRDRI---VGDYQQLEERHLSIILEKDQLIQEAAAENNKLK 2509
Query: 226 -EIAILRNTIRDL 237
EI LR+ + DL
Sbjct: 2510 EEIRGLRSHMDDL 2522
Score = 39.7 bits (91), Expect = 0.003
Identities = 49/227 (21%), Positives = 96/227 (42%), Gaps = 33/227 (14%)
Query: 44 QLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQNL-KGENEQLKISADL--- 99
QL++ + +QA+ + E A +++ E Q L + E QL AD+
Sbjct: 191 QLQEKEEFISTLQAQLSQTQAEQAA-QQVVREKDARFETQVRLHEDELLQLVTQADVETE 249
Query: 100 -------IKEKLKSHEQEY--KNNIAKLVSEMKIKEEGYKKEISKLYQDMQRK------- 143
++ KL+ HE+ + + L+ + E + +S+ Q M+ +
Sbjct: 250 MQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 309
Query: 144 VELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQD 203
VE E+ K L+EK E+E++E + ++E + + + + A A+ + +S+
Sbjct: 310 VETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFE---QAGQAQAELESR---- 362
Query: 204 STVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSHLK 250
S +K + EEK I L+ T ++L+ KD + K
Sbjct: 363 -----YSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSK 404
Score = 39.7 bits (91), Expect = 0.003
Identities = 50/256 (19%), Positives = 116/256 (45%), Gaps = 39/256 (15%)
Query: 23 DFSQIEKKMVETNGKNNILDIQ----LEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQ 78
+ ++E + + +N +L+ + ++K+N L++ ++ + ++ A L + +K +
Sbjct: 2409 EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSS 2468
Query: 79 TIEYQQNLKGENEQLK---ISADLIKEKL------------------KSHEQEYKNNIAK 117
+ + G+ +QL+ +S L K++L +SH + + AK
Sbjct: 2469 LQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAK 2528
Query: 118 LVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKEL------IEKKEMEISELNAKLRS 171
L +E+ E + I+ ++ +E+ +++KEL +E+K E E N LR
Sbjct: 2529 LDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRR 2588
Query: 172 QEKEKQNEIIKLQLEFDA---KLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIA 228
Q E L E ++ ++++ + + Q+ L +Y +L+ +EE ++ A
Sbjct: 2589 SFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTL--GLYHAQLKVKEEEVHRLSA 2646
Query: 229 ILRNT---IRDLEQRL 241
+ ++ I +LE+ L
Sbjct: 2647 LFSSSQKRIAELEEEL 2662
Score = 38.5 bits (88), Expect = 0.006
Identities = 57/249 (22%), Positives = 111/249 (44%), Gaps = 39/249 (15%)
Query: 18 DKLIN--DFSQIEKKMVETNGKNNILDIQ--LEKSNCLLKVMQAKEVSIKEECATLHNII 73
DKLI D S +E + + ++ ++ L ++ E L+K +++ + S E
Sbjct: 1549 DKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKH 1608
Query: 74 KGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEI 133
K LQ+ E L E + A+ I+ +++ QE + KL S E KKE
Sbjct: 1609 KELQKEYEI---LLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRST-----EANKKET 1660
Query: 134 SKLYQDMQRKVELNEEKHKELIEKKEMEISEL---NAKLRSQ-------EKEKQNEIIKL 183
K Q+ ++++E +EK ++ + K+ +I EL N +LR++ KE ++
Sbjct: 1661 EKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSS 1720
Query: 184 QLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRL-- 241
+L RV+ + ++ +K Q EK+ L ++DL+ ++
Sbjct: 1721 NASMKEELERVKMEYETLS-----------KKFQSLMSEKDS----LSEEVQDLKHQIEG 1765
Query: 242 SVGKDSHLK 250
+V K ++L+
Sbjct: 1766 NVSKQANLE 1774
Score = 38.1 bits (87), Expect = 0.007
Identities = 34/155 (21%), Positives = 74/155 (47%), Gaps = 11/155 (7%)
Query: 97 ADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEE---KHKE 153
A+++ +L + +N A L E+ +E + + +D+Q ++ E+ + K+
Sbjct: 9 ANVVLHELSGDDDTDQNMRAPLDPELH--QESDMEFNNTTQEDVQERLAYAEQLVVELKD 66
Query: 154 LIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQ--TKSKSYQDSTVLPQSI 211
+I +K++++ + + L+ + K N+I KL+L AKL + + Q TVLP
Sbjct: 67 IIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEP 126
Query: 212 YRR----KLQHFQEEKNKEIAILRNTIRDLEQRLS 242
K E+ EI +++ +++ E+ +S
Sbjct: 127 QSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELIS 161
Score = 37.4 bits (85), Expect = 0.013
Identities = 55/239 (23%), Positives = 103/239 (43%), Gaps = 46/239 (19%)
Query: 26 QIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHN----IIKGLQQTIE 81
++E ++ G ++ ++Q K + L K++ KE + L + K + IE
Sbjct: 1373 KLESSQLQIAGLEHLRELQ-PKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIE 1431
Query: 82 YQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQ 141
+ +K + QL++ A E++K + E + EMK K E +E S+ Q +Q
Sbjct: 1432 QEDLIKALHTQLEMQAKEHDERIKQLQVE--------LCEMKQKPEEIGEE-SRAKQQIQ 1482
Query: 142 RKVEL-----------NEEKHKEL------IEKKEMEISELNAKLRSQEKEK-------- 176
RK++ N+ +EL IE+ ++++ +++ +Q KEK
Sbjct: 1483 RKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLA 1542
Query: 177 --QNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNT 233
Q E KL E D L Q+ S S + + + + K E+ KEI L+++
Sbjct: 1543 LLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDK-----EKLVKEIESLKSS 1596
Score = 33.9 bits (76), Expect = 0.14
Identities = 51/232 (21%), Positives = 100/232 (43%), Gaps = 20/232 (8%)
Query: 25 SQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTI---- 80
S+ E+ VE + +N + S C + K+ +I E+ L +I K L++ +
Sbjct: 1030 SETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQ-TISEKEVELQHIRKDLEEKLAAEE 1088
Query: 81 EYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDM 140
++Q +K N+ L+ + I + L++ E + I KL++ +G + K +
Sbjct: 1089 QFQALVKQMNQTLQDKTNQI-DLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVI 1147
Query: 141 QRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAK---LARVQTK 197
+ E K EL K+ + EKEK+ KLQ ++ L + Q K
Sbjct: 1148 SPPCTGSSEHWKP----------ELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEK 1197
Query: 198 SKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSHL 249
+ ++ + Y R + F +E++KE + + +R L+ ++ D L
Sbjct: 1198 ERHLREELKQQKDDYNRLQEQF-DEQSKENENIGDQLRQLQIQVRESIDGKL 1248
Score = 32.3 bits (72), Expect = 0.41
Identities = 42/201 (20%), Positives = 94/201 (46%), Gaps = 33/201 (16%)
Query: 47 KSNCLLKVMQAKEVS--IKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKL 104
+ C V AK + + ++ ++ I LQQ + ++ + G E+ K+K
Sbjct: 1808 RPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEE--------KQKN 1859
Query: 105 KSHEQEYKNNIAKLVSEMKIKEEGYK---KEISKL-------YQDMQRKVELNE--EKHK 152
K Q +N L+S++ K+ K +E++K+ +++ R +L E E+ K
Sbjct: 1860 KEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEK 1919
Query: 153 ELIEKKEM-EISELNAKLRS-----QEKEKQNEIIKLQLEFDAKLAR--VQTKSKSYQDS 204
+ +E++ M +++ELN + + + + +NE+++ +++ K + K + ++
Sbjct: 1920 DDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEK 1979
Query: 205 TVLPQSI---YRRKLQHFQEE 222
T + I Y K+Q Q+E
Sbjct: 1980 TKVESEIRKEYLEKIQGAQKE 2000
Score = 31.2 bits (69), Expect = 0.91
Identities = 52/249 (20%), Positives = 111/249 (44%), Gaps = 21/249 (8%)
Query: 19 KLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEV---SIKEECATLHNIIKG 75
K+ + S++ KK E ++ Q + L V EV S++++ + I G
Sbjct: 1324 KVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAG 1383
Query: 76 LQQTIEYQQNL--------KGENEQLKISADLIKE-----KLKSHEQEYKNNIAKLVSEM 122
L+ E Q L K E + +S L ++ K+++ E ++ I L +++
Sbjct: 1384 LEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQL 1443
Query: 123 KIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIK 182
+++ + + + I +L ++ + EE +E K++++ A + +E K+N+ ++
Sbjct: 1444 EMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQ 1503
Query: 183 LQLEFDAKLARVQTKSKSYQDSTVLPQSIYR----RKLQHFQEEKNKEIAILRNTIRDLE 238
+L TKS + +S V Q+ + +L QEE++K I + ++ +
Sbjct: 1504 EELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLE-N 1562
Query: 239 QRLSVGKDS 247
Q LS +S
Sbjct: 1563 QSLSSSCES 1571
Score = 28.1 bits (61), Expect = 7.7
Identities = 38/199 (19%), Positives = 85/199 (42%), Gaps = 24/199 (12%)
Query: 3 QSSEGCMKKISSVNLDKLINDFSQIEKKMVETNGKN---NILDIQLEKSNCLLKVMQAKE 59
QS + M + + + D+L+ + ++++ ++ N + + L QL++ K Q +
Sbjct: 2877 QSLKKAMSSLQN-DRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQ 2935
Query: 60 VSIKEECAT----LHNI--------IKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSH 107
+++E + LH + I + +Y + +++QL +LI+E S
Sbjct: 2936 EELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSS 2995
Query: 108 EQEYKNNIA---KLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISE 164
Q + + E +G + + Y+ + +LN+ + I +KE+ I +
Sbjct: 2996 SQTQPLKVQYQRQASPETSASPDGSQNLV---YETELLRTQLNDSLKE--IHQKELRIQQ 3050
Query: 165 LNAKLRSQEKEKQNEIIKL 183
LN+ +EK I+L
Sbjct: 3051 LNSNFSQLLEEKNTLSIQL 3069
>gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens]
Length = 757
Score = 50.8 bits (120), Expect = 1e-06
Identities = 48/184 (26%), Positives = 92/184 (50%), Gaps = 23/184 (12%)
Query: 61 SIKEECATLHNIIKGLQQTIEYQQ-NLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLV 119
S+KE A + + + + E Q+ NL EN+ L++S + ++ L S ++E + KL
Sbjct: 277 SLKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEE----LNKLR 332
Query: 120 SEMKIKEE-GYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQN 178
+++I E+ G E+ K Q +++ +E ++K + ++E ++E AK+ +E E++
Sbjct: 333 EQIRILEDKGTSTELVKENQKLKQHLEEEKQKKHSFLSQRETLLTE--AKMLKRELERE- 389
Query: 179 EIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLE 238
+L A +Q S S ++Y K KEIAILR + +LE
Sbjct: 390 -----RLVTTALRGELQQLSGSQLHGKSDSPNVYTEK---------KEIAILRERLTELE 435
Query: 239 QRLS 242
++L+
Sbjct: 436 RKLT 439
>gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens]
Length = 757
Score = 50.8 bits (120), Expect = 1e-06
Identities = 48/184 (26%), Positives = 92/184 (50%), Gaps = 23/184 (12%)
Query: 61 SIKEECATLHNIIKGLQQTIEYQQ-NLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLV 119
S+KE A + + + + E Q+ NL EN+ L++S + ++ L S ++E + KL
Sbjct: 277 SLKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEE----LNKLR 332
Query: 120 SEMKIKEE-GYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQN 178
+++I E+ G E+ K Q +++ +E ++K + ++E ++E AK+ +E E++
Sbjct: 333 EQIRILEDKGTSTELVKENQKLKQHLEEEKQKKHSFLSQRETLLTE--AKMLKRELERE- 389
Query: 179 EIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLE 238
+L A +Q S S ++Y K KEIAILR + +LE
Sbjct: 390 -----RLVTTALRGELQQLSGSQLHGKSDSPNVYTEK---------KEIAILRERLTELE 435
Query: 239 QRLS 242
++L+
Sbjct: 436 RKLT 439
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 50.4 bits (119), Expect = 1e-06
Identities = 65/220 (29%), Positives = 93/220 (42%), Gaps = 49/220 (22%)
Query: 76 LQQTIEYQQNLKGENEQLKI-----SADLIKEKLKSHEQ---EYKNNIAKLVSEMKIKEE 127
L T + Q ENE LKI S +L +KLK+ E+ E K + +L +K+KE+
Sbjct: 679 LSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKED 738
Query: 128 GYK---------KEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQN 178
K K +SK Y K+E + E+ K + + + ++ EL K S K
Sbjct: 739 LIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMK-- 796
Query: 179 EIIKLQLEF----DAKLARVQTKSKSYQDS--------------TVLPQSIYRRKLQHFQ 220
+KLQ EF DA RVQ K QDS L QS+ K Q Q
Sbjct: 797 --VKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQ 854
Query: 221 --------EEKNKEI--AILRNTIRDLEQRLSVGKDSHLK 250
EK K++ I R+ + E +L G++ LK
Sbjct: 855 LQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLK 894
Score = 38.1 bits (87), Expect = 0.007
Identities = 66/287 (22%), Positives = 124/287 (43%), Gaps = 48/287 (16%)
Query: 9 MKKISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECAT 68
+ K S+ + KL +D Q + +++ET + L+ + + S+ +KV KE K + A
Sbjct: 753 VSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENK-DLSDVAMKVKLQKEFRKKMDAAK 811
Query: 69 LH-NIIKGLQQTIEYQQNLKGENE----QLKISADLIK-------EKLKSHEQEYKNNIA 116
L +++ QQ + +L +NE +L+ S D +K KL+ ++ K A
Sbjct: 812 LRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDA 871
Query: 117 KL------VSEMKIK---EEGYKKE------------------ISKLYQDMQRKVELNEE 149
+ + E+++K EEG K + I L + ++K L+EE
Sbjct: 872 VIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEE 931
Query: 150 KHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQ 209
K L +++E+E E + K R K+ +++ + + K + +S ++ L
Sbjct: 932 VEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENK----KLRSSQALNTDSLKI 987
Query: 210 SIYRRKLQHFQEEKNKEI----AILRNTIRDLEQRLSVGKDSHLKRR 252
S L+ EKN ++ A + I + + L KD KRR
Sbjct: 988 STRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRR 1034
Score = 32.7 bits (73), Expect = 0.31
Identities = 47/201 (23%), Positives = 84/201 (41%), Gaps = 26/201 (12%)
Query: 43 IQLEKSNCLLKVMQAKEVSIKEECAT--LHNIIKGLQQTIEYQQNLKGENEQLKISADLI 100
+Q + N K+ + +S +EE L I+ L+ IEY+ N +N Q + A
Sbjct: 1030 LQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYR-NESIQNRQKSLRASF- 1087
Query: 101 KEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEM 160
L E +A L S ++I+ + L++ + V L E + K+ + +EM
Sbjct: 1088 -HNLSRGEANVLEKLACL-SPVEIR--------TILFRYFNKVVNLREAERKQQLYNEEM 1137
Query: 161 EISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQ 220
++ L +E E + +KLQ + R+ + K ++ L L HF+
Sbjct: 1138 KMKVLERDNMVRELESALDHLKLQCD-----RRLTLQQKEHEQKMQL-------LLHHFK 1185
Query: 221 EEKNKEIAILRNTIRDLEQRL 241
E+ + I T D Q+L
Sbjct: 1186 EQDGEGIMETFKTYEDKIQQL 1206
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 50.1 bits (118), Expect = 2e-06
Identities = 53/231 (22%), Positives = 105/231 (45%), Gaps = 32/231 (13%)
Query: 20 LINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQT 79
++ Q+E E+N K + + E + C L++ Q E IK
Sbjct: 604 MVKRCKQLESTQTESNKKME--ENEKELAACQLRISQ-HEAKIKS--------------L 646
Query: 80 IEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQD 139
EY QN++ + QL+ S D + E+L + K V EM+ + + +++ Q
Sbjct: 647 TEYLQNVEQKKRQLEESVDALSEELVQLRAQEK------VHEMEKEHLNKVQTANEVKQA 700
Query: 140 MQRKVELNEEKHKELIEKKEMEI---SELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQT 196
++++++ + E H++ I E+ ++L L+ Q ++ E +L++E + A Q
Sbjct: 701 VEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQE 760
Query: 197 KSKSYQDSTVLP--QSIYRRKLQHFQEEKNKEIAILRNT----IRDLEQRL 241
KS+ + TV+ + R+ L+ +E KE+ L N ++DL R+
Sbjct: 761 KSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRV 811
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 50.1 bits (118), Expect = 2e-06
Identities = 51/262 (19%), Positives = 117/262 (44%), Gaps = 40/262 (15%)
Query: 11 KISSVNLDKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLL-------KVMQAKEVSIK 63
K + + LD + +++ + +NN+L +LE+ ++ K+ + + +
Sbjct: 1653 KDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETS 1712
Query: 64 EECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNI---AKLVS 120
E LH+ L I ++ ++ + QL+ + ++ ++ E++ K I A +
Sbjct: 1713 ERVQLLHSQNTSL---INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAE 1769
Query: 121 EMKIKE------EGYKKEISKLYQDMQRKVELNEE----KHKELIEKKEMEISELNAKLR 170
E+K ++ E KK + + +D+Q +++ E+ K+ ++K E + EL +L
Sbjct: 1770 ELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELE 1829
Query: 171 SQEK------------EKQNEIIKLQLEFDAK-LARVQTKSKSYQDSTVLPQSIYRRKLQ 217
+++K E++ + + Q E D K L R+Q D L Y+R+ +
Sbjct: 1830 AEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQ----DLVDKLQLKVKAYKRQAE 1885
Query: 218 HFQEEKNKEIAILRNTIRDLEQ 239
+E+ N ++ R +L++
Sbjct: 1886 EAEEQANTNLSKFRKVQHELDE 1907
Score = 43.1 bits (100), Expect = 2e-04
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 17/245 (6%)
Query: 25 SQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQQTIEYQQ 84
++ EK+M + + LEKS K ++ K VS+ +E L ++ Q + +
Sbjct: 845 AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904
Query: 85 NLKGENEQLKISADL-IKEKLKSHEQEYKNNIAKLVSEMKIKEE--GYKKEISKL---YQ 138
+ + KI + +KE + E E + N + K+++E KK+I L
Sbjct: 905 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLA 964
Query: 139 DMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEK----EKQNEIIKLQLEFDAKLARV 194
++++ E K K L E+ + E+ AKL ++K Q + LQ+E D +
Sbjct: 965 KVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLS 1023
Query: 195 QTKSKSYQDSTVLPQSIYRRKLQHFQEEKNK-----EIAILRNTIRDLEQRLSVGKDSHL 249
++K K Q L S+ + K E+ K ++ + + +I DLE + + L
Sbjct: 1024 KSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEND-KLQLEEKL 1082
Query: 250 KRRRF 254
K++ F
Sbjct: 1083 KKKEF 1087
Score = 42.4 bits (98), Expect = 4e-04
Identities = 58/280 (20%), Positives = 129/280 (46%), Gaps = 64/280 (22%)
Query: 18 DKLINDFSQIEKKMVETNGKNNILDIQLEKSNCLLKVMQAKEVSIKEECATLHNIIKGLQ 77
D+LI + Q+E K+ E N + LE + + AK+ +++EC+ L I L+
Sbjct: 908 DQLIKNKIQLEAKVKEMNER-------LEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 78 QTIEY--------QQNLKGENEQL----KISADLIKEKL---KSHEQ---------EYKN 113
T+ + +K E++ +I A L KEK ++H+Q + N
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
Query: 114 NIAKLVSEMKIKE-----EGYKKEISKLYQDMQRK-----------------VELNEEKH 151
+++K S++K+++ EG ++ K+ D++R +E ++ +
Sbjct: 1021 SLSK--SKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1078
Query: 152 KELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSI 211
+E ++KKE +I++ N+K+ + +++ LQL+ KL Q + + ++ ++
Sbjct: 1079 EEKLKKKEFDINQQNSKIEDE------QVLALQLQ--KKLKENQARIEELEEELEAERTA 1130
Query: 212 YRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVGKDSHLKR 251
R K++ + + ++E+ + + + SV + + KR
Sbjct: 1131 -RAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1169
Score = 41.2 bits (95), Expect = 9e-04
Identities = 46/202 (22%), Positives = 96/202 (47%), Gaps = 29/202 (14%)
Query: 58 KEVSIKEECATLHNIIKGLQQTIEYQQNLKGENEQLKISADLIKEKLKSHEQEYKNNI-- 115
K ++E AT+ +++T+E + + E E+ +S K L+ Q ++N+
Sbjct: 843 KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLND 902
Query: 116 AKLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKK----------EMEISEL 165
A+ + IK K ++ ++M ++E EE + EL KK + +I +L
Sbjct: 903 AEERCDQLIKN---KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDL 959
Query: 166 NAKLRSQEKEK---QNEIIKLQLE---FDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHF 219
L EKEK +N++ L E D +A++ + K+ Q++ +++ L
Sbjct: 960 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA-------HQQALDDL 1012
Query: 220 QEEKNKEIAILRNTIRDLEQRL 241
Q E++K ++ ++ ++ LEQ++
Sbjct: 1013 QVEEDKVNSLSKSKVK-LEQQV 1033
Score = 36.6 bits (83), Expect = 0.022
Identities = 49/222 (22%), Positives = 94/222 (42%), Gaps = 24/222 (10%)
Query: 29 KKMVETNGK-NNILD--IQLEKSNC-LLKVMQAKEVSIKEECATLHNIIKG--LQQTIEY 82
K+ +E GK N L +Q + +C LL+ +E K E + + Q +Y
Sbjct: 1318 KRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY 1377
Query: 83 QQNLKGENEQLKISADLIKEKLKSHEQEYKNNIAKLVSEMKIKEEGYKKEISKLYQDMQR 142
+ + E+L+ + + ++L+ E+ + AK S K K + EI L D++R
Sbjct: 1378 ETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHR-LQNEIEDLMVDVER 1436
Query: 143 KVELNEEKHKELIEKKEMEISELNAKLRSQEKEKQNEIIKLQLEFDAKLARVQTKSKSYQ 202
++KK+ ++ A+ + + +E Q+E L Q +++S
Sbjct: 1437 S-----NAAAAALDKKQRNFDKILAEWKQKYEESQSE-----------LESSQKEARSLS 1480
Query: 203 DSTVLPQSIYRRKLQHFQEEKNKEIAILRNTIRDLEQRLSVG 244
++ Y L+H + K +E L+ I DL ++L G
Sbjct: 1481 TELFKLKNAYEESLEHLETFK-RENKNLQEEISDLTEQLGEG 1521
Score = 28.1 bits (61), Expect = 7.7
Identities = 30/131 (22%), Positives = 58/131 (44%), Gaps = 23/131 (17%)
Query: 131 KEISKLYQDMQRKVELNEE--KHKELIEKKEMEISELNAKLRS--QEK------------ 174
K + K + + + EE + KE +EK E EL K+ S QEK
Sbjct: 839 KPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898
Query: 175 ------EKQNEIIKLQLEFDAKLARVQTKSKSYQDSTVLPQSIYRRKLQHFQEEKNKEIA 228
E+ +++IK +++ +AK+ + + + ++ + +RKL+ E K+I
Sbjct: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNA-ELTAKKRKLEDECSELKKDID 957
Query: 229 ILRNTIRDLEQ 239
L T+ +E+
Sbjct: 958 DLELTLAKVEK 968
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.324
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,083,511
Number of Sequences: 37866
Number of extensions: 355359
Number of successful extensions: 6327
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 310
Number of HSP's successfully gapped in prelim test: 897
Number of HSP's that attempted gapping in prelim test: 3028
Number of HSP's gapped (non-prelim): 2921
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.