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Search of human proteins with 198041728
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
(545 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens] 1088 0.0
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens] 946 0.0
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens] 946 0.0
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens] 946 0.0
gi|41871960 kinesin-like 8 isoform b [Homo sapiens] 647 0.0
gi|41871955 kinesin-like 8 isoform a [Homo sapiens] 647 0.0
gi|41871946 kinesin-like 8 isoform a [Homo sapiens] 647 0.0
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 626 e-179
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 575 e-164
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 572 e-163
gi|91825557 kinesin light chain 3 [Homo sapiens] 363 e-100
gi|19923891 kinesin-like 8 isoform c [Homo sapiens] 211 1e-54
gi|34304360 nephrocystin 3 [Homo sapiens] 146 4e-35
gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens] 56 1e-07
gi|87162455 hypothetical protein LOC23277 [Homo sapiens] 55 2e-07
gi|18104962 amyloid beta precursor protein-binding protein 2 [Ho... 55 2e-07
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 54 5e-07
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 54 5e-07
gi|22749211 transmembrane and tetratricopeptide repeat containin... 50 7e-06
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 46 8e-05
gi|83415184 transmembrane and tetratricopeptide repeat containin... 45 2e-04
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 42 0.001
gi|116089276 tetratricopeptide repeat domain 23-like [Homo sapiens] 41 0.003
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 39 0.016
gi|17864094 feminization 1 homolog a [Homo sapiens] 39 0.016
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 37 0.035
gi|118766328 transmembrane and tetratricopeptide repeat containi... 37 0.035
gi|118766330 transmembrane and tetratricopeptide repeat containi... 37 0.035
gi|24308163 fem-1 homolog a [Homo sapiens] 37 0.046
gi|239755782 PREDICTED: hypothetical protein XP_002344710 [Homo ... 36 0.10
>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
Length = 545
Score = 1088 bits (2814), Expect = 0.0
Identities = 545/545 (100%), Positives = 545/545 (100%)
Query: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
Sbjct: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
Query: 61 LRRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPAR 120
LRRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPAR
Sbjct: 61 LRRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPAR 120
Query: 121 LRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYK 180
LRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYK
Sbjct: 121 LRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYK 180
Query: 181 EAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLG 240
EAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLG
Sbjct: 181 EAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLG 240
Query: 241 KFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYL 300
KFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYL
Sbjct: 241 KFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYL 300
Query: 301 KQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSW 360
KQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSW
Sbjct: 301 KQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSW 360
Query: 361 YKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKD 420
YKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKD
Sbjct: 361 YKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKD 420
Query: 421 GSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSS 480
GSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSS
Sbjct: 421 GSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSS 480
Query: 481 EMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRR 540
EMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRR
Sbjct: 481 EMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRR 540
Query: 541 SSLVG 545
SSLVG
Sbjct: 541 SSLVG 545
>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 946 bits (2446), Expect = 0.0
Identities = 477/524 (91%), Positives = 489/524 (93%), Gaps = 1/524 (0%)
Query: 22 KAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQEEKGD 81
+ ++Q + LR E L E A+ +++ +L + ++ EEKGD
Sbjct: 100 RRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDED-ASPNEEKGD 158
Query: 82 VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV 141
VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV
Sbjct: 159 VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV 218
Query: 142 PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH 201
PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH
Sbjct: 219 PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH 278
Query: 202 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 261
PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG
Sbjct: 279 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 338
Query: 262 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE
Sbjct: 339 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Query: 322 KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL 381
KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL
Sbjct: 399 KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL 458
Query: 382 YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR 441
YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR
Sbjct: 459 YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR 518
Query: 442 SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK 501
SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK
Sbjct: 519 SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK 578
Query: 502 RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 545
RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG
Sbjct: 579 RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 622
Score = 221 bits (563), Expect = 1e-57
Identities = 169/420 (40%), Positives = 213/420 (50%), Gaps = 58/420 (13%)
Query: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
Sbjct: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
Query: 61 LRRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPAR 120
LRRSLEAIELGLGEAQ V L E E+ +
Sbjct: 61 LRRSLEAIELGLGEAQ-----VILALSSHLGAVESEKQ---------------------K 94
Query: 121 LRTLHNLVIQYASQGRYEVA-----VPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
LR ++Q R E+A + +QA+ LE+ H ++ + + D
Sbjct: 95 LRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQH-----LLFMSQIRKLDED 149
Query: 176 QNKYKEAAHLLNDALAIREKTLGKDHPA----------------VAATLNNL---AVLYG 216
+ +E + D L + PA + A L L + Y
Sbjct: 150 ASPNEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 209
Query: 217 KRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 276
+G+Y+ A PLCK+ALE EK G HPDVA L+ LAL+ ++Q K +E + AL I
Sbjct: 210 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 269
Query: 277 YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWM 336
LG D P VA T NNLA Y K+GKY++AE L K L EK G + D
Sbjct: 270 REKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRAL-EIREKVLGKFHPDVAKQLS 328
Query: 337 HAEEREESKDKRRDSAPYGEYGSWYKACKV--DSPTVNTTLRSLGALYRRQGKLEAAHTL 394
+ +++ K + Y A ++ D P V T +L + Y +QGK + A TL
Sbjct: 329 NLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETL 388
>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 946 bits (2446), Expect = 0.0
Identities = 477/524 (91%), Positives = 489/524 (93%), Gaps = 1/524 (0%)
Query: 22 KAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQEEKGD 81
+ ++Q + LR E L E A+ +++ +L + ++ EEKGD
Sbjct: 100 RRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDED-ASPNEEKGD 158
Query: 82 VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV 141
VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV
Sbjct: 159 VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV 218
Query: 142 PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH 201
PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH
Sbjct: 219 PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH 278
Query: 202 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 261
PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG
Sbjct: 279 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 338
Query: 262 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE
Sbjct: 339 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Query: 322 KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL 381
KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL
Sbjct: 399 KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL 458
Query: 382 YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR 441
YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR
Sbjct: 459 YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR 518
Query: 442 SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK 501
SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK
Sbjct: 519 SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK 578
Query: 502 RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 545
RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG
Sbjct: 579 RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 622
Score = 221 bits (563), Expect = 1e-57
Identities = 169/420 (40%), Positives = 213/420 (50%), Gaps = 58/420 (13%)
Query: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
Sbjct: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
Query: 61 LRRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPAR 120
LRRSLEAIELGLGEAQ V L E E+ +
Sbjct: 61 LRRSLEAIELGLGEAQ-----VILALSSHLGAVESEKQ---------------------K 94
Query: 121 LRTLHNLVIQYASQGRYEVA-----VPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
LR ++Q R E+A + +QA+ LE+ H ++ + + D
Sbjct: 95 LRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQH-----LLFMSQIRKLDED 149
Query: 176 QNKYKEAAHLLNDALAIREKTLGKDHPA----------------VAATLNNL---AVLYG 216
+ +E + D L + PA + A L L + Y
Sbjct: 150 ASPNEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 209
Query: 217 KRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 276
+G+Y+ A PLCK+ALE EK G HPDVA L+ LAL+ ++Q K +E + AL I
Sbjct: 210 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 269
Query: 277 YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWM 336
LG D P VA T NNLA Y K+GKY++AE L K L EK G + D
Sbjct: 270 REKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRAL-EIREKVLGKFHPDVAKQLS 328
Query: 337 HAEEREESKDKRRDSAPYGEYGSWYKACKV--DSPTVNTTLRSLGALYRRQGKLEAAHTL 394
+ +++ K + Y A ++ D P V T +L + Y +QGK + A TL
Sbjct: 329 NLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETL 388
>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 946 bits (2446), Expect = 0.0
Identities = 477/524 (91%), Positives = 489/524 (93%), Gaps = 1/524 (0%)
Query: 22 KAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQEEKGD 81
+ ++Q + LR E L E A+ +++ +L + ++ EEKGD
Sbjct: 100 RRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDED-ASPNEEKGD 158
Query: 82 VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV 141
VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV
Sbjct: 159 VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV 218
Query: 142 PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH 201
PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH
Sbjct: 219 PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH 278
Query: 202 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 261
PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG
Sbjct: 279 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 338
Query: 262 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE
Sbjct: 339 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
Query: 322 KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL 381
KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL
Sbjct: 399 KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL 458
Query: 382 YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR 441
YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR
Sbjct: 459 YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR 518
Query: 442 SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK 501
SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK
Sbjct: 519 SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK 578
Query: 502 RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 545
RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG
Sbjct: 579 RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 622
Score = 221 bits (563), Expect = 1e-57
Identities = 169/420 (40%), Positives = 213/420 (50%), Gaps = 58/420 (13%)
Query: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
Sbjct: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
Query: 61 LRRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPAR 120
LRRSLEAIELGLGEAQ V L E E+ +
Sbjct: 61 LRRSLEAIELGLGEAQ-----VILALSSHLGAVESEKQ---------------------K 94
Query: 121 LRTLHNLVIQYASQGRYEVA-----VPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
LR ++Q R E+A + +QA+ LE+ H ++ + + D
Sbjct: 95 LRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQH-----LLFMSQIRKLDED 149
Query: 176 QNKYKEAAHLLNDALAIREKTLGKDHPA----------------VAATLNNL---AVLYG 216
+ +E + D L + PA + A L L + Y
Sbjct: 150 ASPNEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 209
Query: 217 KRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 276
+G+Y+ A PLCK+ALE EK G HPDVA L+ LAL+ ++Q K +E + AL I
Sbjct: 210 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 269
Query: 277 YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWM 336
LG D P VA T NNLA Y K+GKY++AE L K L EK G + D
Sbjct: 270 REKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRAL-EIREKVLGKFHPDVAKQLS 328
Query: 337 HAEEREESKDKRRDSAPYGEYGSWYKACKV--DSPTVNTTLRSLGALYRRQGKLEAAHTL 394
+ +++ K + Y A ++ D P V T +L + Y +QGK + A TL
Sbjct: 329 NLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETL 388
>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
Length = 637
Score = 647 bits (1670), Expect = 0.0
Identities = 336/471 (71%), Positives = 376/471 (79%), Gaps = 18/471 (3%)
Query: 75 AQEEKGDVPKDTLDDLFPNEDEQSPAP--SPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 132
++E++GD KD+LDDLFPNE+E+ P+ S G G + Q GGYEIPARLRTLHNLVIQYA
Sbjct: 181 SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA 240
Query: 133 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 192
+QGRYEVAVPLCKQALEDLE+TSG HPDVATMLNILALVYRDQNKYKEAAHLLNDAL+I
Sbjct: 241 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI 300
Query: 193 REKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSN 252
RE TLG DHPAVAATLNNLAVLYGKRGKYKEAEPLC+RALEIREKVLG HPDVAKQL+N
Sbjct: 301 RESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNN 360
Query: 253 LALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLY 312
LALLCQNQGK E VE YY+RAL IY +LGPD+PNVA+TKNNLASCYLKQGKY +AETLY
Sbjct: 361 LALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY 420
Query: 313 KEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKR--RDSAPYGEYGSWYKACKVDSPT 370
KEILTRAH +EFGSV+ D+KPIWMHAEEREE R PY EYG WYKACKV SPT
Sbjct: 421 KEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPT 480
Query: 371 VNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRS 430
VNTTLR+LGALYRRQGKLEAA TLE+CA R+R+QG DP SQTKV ELL + GRR +
Sbjct: 481 VNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEG 540
Query: 431 SRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGG 490
D G ED EW+GDGSG+L+RSGS GK+RD LRRSSE+LV+KLQG
Sbjct: 541 PGDSVKFEGG------EDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGT 594
Query: 491 TPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRS 541
P+ P + MKRA+SLN+LN QP L SR LS+S+MDLS S
Sbjct: 595 EPR-PSSSNMKRAASLNYLN-------QPSAAPLQVSRGLSASTMDLSSSS 637
Score = 143 bits (360), Expect = 5e-34
Identities = 132/408 (32%), Positives = 194/408 (47%), Gaps = 38/408 (9%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 30 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 89
Query: 62 RRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPS------PGGGDVSGQHGGY 115
RRS+E IELGL EAQ V L E E+ + + + G
Sbjct: 90 RRSMENIELGLSEAQ-----VMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGT 144
Query: 116 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
+ RL+ V Q + ++ + +Q ED TS D + L ++ +
Sbjct: 145 Q--QRLQRSEQAVAQLEEEKKHLEFLGQLRQYDED-GHTSEEKEGDATK--DSLDDLFPN 199
Query: 176 QNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIR 235
+ + + L A + G + PA TL+NL + Y +G+Y+ A PLCK+ALE
Sbjct: 200 EEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDL 259
Query: 236 EKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 295
E+ G+ HPDVA L+ LAL+ ++Q K +E + AL I + LGPD P VA T NNL
Sbjct: 260 ERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNL 319
Query: 296 ASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGD------NKPIWMHAEEREESKDK-- 347
A Y K+GKY++AE L + L EK G+ + D N + + + E+ ++
Sbjct: 320 AVLYGKRGKYKEAEPLCQRAL-EIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY 378
Query: 348 RRDSAPY-GEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTL 394
+R A Y G+ G D+P V T +L + Y +QGK A TL
Sbjct: 379 QRALAIYEGQLGP-------DNPNVARTKNNLASCYLKQGKYAEAETL 419
>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 647 bits (1670), Expect = 0.0
Identities = 336/471 (71%), Positives = 376/471 (79%), Gaps = 18/471 (3%)
Query: 75 AQEEKGDVPKDTLDDLFPNEDEQSPAP--SPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 132
++E++GD KD+LDDLFPNE+E+ P+ S G G + Q GGYEIPARLRTLHNLVIQYA
Sbjct: 163 SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA 222
Query: 133 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 192
+QGRYEVAVPLCKQALEDLE+TSG HPDVATMLNILALVYRDQNKYKEAAHLLNDAL+I
Sbjct: 223 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI 282
Query: 193 REKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSN 252
RE TLG DHPAVAATLNNLAVLYGKRGKYKEAEPLC+RALEIREKVLG HPDVAKQL+N
Sbjct: 283 RESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNN 342
Query: 253 LALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLY 312
LALLCQNQGK E VE YY+RAL IY +LGPD+PNVA+TKNNLASCYLKQGKY +AETLY
Sbjct: 343 LALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY 402
Query: 313 KEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKR--RDSAPYGEYGSWYKACKVDSPT 370
KEILTRAH +EFGSV+ D+KPIWMHAEEREE R PY EYG WYKACKV SPT
Sbjct: 403 KEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPT 462
Query: 371 VNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRS 430
VNTTLR+LGALYRRQGKLEAA TLE+CA R+R+QG DP SQTKV ELL + GRR +
Sbjct: 463 VNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEG 522
Query: 431 SRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGG 490
D G ED EW+GDGSG+L+RSGS GK+RD LRRSSE+LV+KLQG
Sbjct: 523 PGDSVKFEGG------EDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGT 576
Query: 491 TPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRS 541
P+ P + MKRA+SLN+LN QP L SR LS+S+MDLS S
Sbjct: 577 EPR-PSSSNMKRAASLNYLN-------QPSAAPLQVSRGLSASTMDLSSSS 619
Score = 143 bits (360), Expect = 5e-34
Identities = 132/408 (32%), Positives = 194/408 (47%), Gaps = 38/408 (9%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
Query: 62 RRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPS------PGGGDVSGQHGGY 115
RRS+E IELGL EAQ V L E E+ + + + G
Sbjct: 72 RRSMENIELGLSEAQ-----VMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGT 126
Query: 116 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
+ RL+ V Q + ++ + +Q ED TS D + L ++ +
Sbjct: 127 Q--QRLQRSEQAVAQLEEEKKHLEFLGQLRQYDED-GHTSEEKEGDATK--DSLDDLFPN 181
Query: 176 QNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIR 235
+ + + L A + G + PA TL+NL + Y +G+Y+ A PLCK+ALE
Sbjct: 182 EEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDL 241
Query: 236 EKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 295
E+ G+ HPDVA L+ LAL+ ++Q K +E + AL I + LGPD P VA T NNL
Sbjct: 242 ERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNL 301
Query: 296 ASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGD------NKPIWMHAEEREESKDK-- 347
A Y K+GKY++AE L + L EK G+ + D N + + + E+ ++
Sbjct: 302 AVLYGKRGKYKEAEPLCQRAL-EIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY 360
Query: 348 RRDSAPY-GEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTL 394
+R A Y G+ G D+P V T +L + Y +QGK A TL
Sbjct: 361 QRALAIYEGQLGP-------DNPNVARTKNNLASCYLKQGKYAEAETL 401
>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 647 bits (1670), Expect = 0.0
Identities = 336/471 (71%), Positives = 376/471 (79%), Gaps = 18/471 (3%)
Query: 75 AQEEKGDVPKDTLDDLFPNEDEQSPAP--SPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 132
++E++GD KD+LDDLFPNE+E+ P+ S G G + Q GGYEIPARLRTLHNLVIQYA
Sbjct: 163 SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA 222
Query: 133 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 192
+QGRYEVAVPLCKQALEDLE+TSG HPDVATMLNILALVYRDQNKYKEAAHLLNDAL+I
Sbjct: 223 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI 282
Query: 193 REKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSN 252
RE TLG DHPAVAATLNNLAVLYGKRGKYKEAEPLC+RALEIREKVLG HPDVAKQL+N
Sbjct: 283 RESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNN 342
Query: 253 LALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLY 312
LALLCQNQGK E VE YY+RAL IY +LGPD+PNVA+TKNNLASCYLKQGKY +AETLY
Sbjct: 343 LALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLY 402
Query: 313 KEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKR--RDSAPYGEYGSWYKACKVDSPT 370
KEILTRAH +EFGSV+ D+KPIWMHAEEREE R PY EYG WYKACKV SPT
Sbjct: 403 KEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPT 462
Query: 371 VNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRS 430
VNTTLR+LGALYRRQGKLEAA TLE+CA R+R+QG DP SQTKV ELL + GRR +
Sbjct: 463 VNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEG 522
Query: 431 SRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGG 490
D G ED EW+GDGSG+L+RSGS GK+RD LRRSSE+LV+KLQG
Sbjct: 523 PGDSVKFEGG------EDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGT 576
Query: 491 TPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRS 541
P+ P + MKRA+SLN+LN QP L SR LS+S+MDLS S
Sbjct: 577 EPR-PSSSNMKRAASLNYLN-------QPSAAPLQVSRGLSASTMDLSSSS 619
Score = 143 bits (360), Expect = 5e-34
Identities = 132/408 (32%), Positives = 194/408 (47%), Gaps = 38/408 (9%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
Query: 62 RRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPS------PGGGDVSGQHGGY 115
RRS+E IELGL EAQ V L E E+ + + + G
Sbjct: 72 RRSMENIELGLSEAQ-----VMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGT 126
Query: 116 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
+ RL+ V Q + ++ + +Q ED TS D + L ++ +
Sbjct: 127 Q--QRLQRSEQAVAQLEEEKKHLEFLGQLRQYDED-GHTSEEKEGDATK--DSLDDLFPN 181
Query: 176 QNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIR 235
+ + + L A + G + PA TL+NL + Y +G+Y+ A PLCK+ALE
Sbjct: 182 EEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDL 241
Query: 236 EKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 295
E+ G+ HPDVA L+ LAL+ ++Q K +E + AL I + LGPD P VA T NNL
Sbjct: 242 ERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNL 301
Query: 296 ASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGD------NKPIWMHAEEREESKDK-- 347
A Y K+GKY++AE L + L EK G+ + D N + + + E+ ++
Sbjct: 302 AVLYGKRGKYKEAEPLCQRAL-EIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY 360
Query: 348 RRDSAPY-GEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTL 394
+R A Y G+ G D+P V T +L + Y +QGK A TL
Sbjct: 361 QRALAIYEGQLGP-------DNPNVARTKNNLASCYLKQGKYAEAETL 401
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 626 bits (1614), Expect = e-179
Identities = 328/499 (65%), Positives = 382/499 (76%), Gaps = 10/499 (2%)
Query: 22 KAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQEEKGD 81
+ + Q + LR E L E A+ +++ + L+ + + ++++ D
Sbjct: 111 RRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTD 170
Query: 82 VPKDTLDDLFPNEDE---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYE 138
K+ LDDLFPN+++ Q + Q GGYEIPARLRTLHNLVIQYASQGRYE
Sbjct: 171 STKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYE 230
Query: 139 VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLG 198
VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLG
Sbjct: 231 VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLG 290
Query: 199 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQ 258
KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQ
Sbjct: 291 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQ 350
Query: 259 NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR 318
NQGK EEVEYYY+RALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTR
Sbjct: 351 NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTR 410
Query: 319 AHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSL 378
AHE+EFGSV+ +NKPIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++L
Sbjct: 411 AHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNL 470
Query: 379 GALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGA 438
GALYRRQGK EAA TLE+ A R+RKQGLD + +V E+L D ++R SR+
Sbjct: 471 GALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVD 528
Query: 439 GPRSESDL---EDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQ-- 493
+ ES E+V + EWNGDG+GSL+RSGSF KLR ++RRSSE LV+KL+GG+ +
Sbjct: 529 VVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRES 588
Query: 494 EPPNPRMKRASSLNFLNKS 512
EP NP A L N S
Sbjct: 589 EPKNPGASLAEPLFVENDS 607
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 575 bits (1481), Expect = e-164
Identities = 298/446 (66%), Positives = 344/446 (77%), Gaps = 8/446 (1%)
Query: 22 KAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQEEKGD 81
+ + Q + LR E L E A+ +++ + L+ + + ++++ D
Sbjct: 111 RRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTD 170
Query: 82 VPKDTLDDLFPNEDE---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYE 138
K+ LDDLFPN+++ Q + Q GGYEIPARLRTLHNLVIQYASQGRYE
Sbjct: 171 STKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYE 230
Query: 139 VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLG 198
VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLG
Sbjct: 231 VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLG 290
Query: 199 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQ 258
KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQ
Sbjct: 291 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQ 350
Query: 259 NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR 318
NQGK EEVEYYY+RALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTR
Sbjct: 351 NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTR 410
Query: 319 AHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSL 378
AHE+EFGSV+ +NKPIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++L
Sbjct: 411 AHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNL 470
Query: 379 GALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGA 438
GALYRRQGK EAA TLE+ A R+RKQGLD + +V E+L D ++R SR+
Sbjct: 471 GALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVD 528
Query: 439 GPRSESDL---EDVGPTAEWNGDGSG 461
+ ES E+V + EWNG SG
Sbjct: 529 VVKYESGPDGGEEVSMSVEWNGGVSG 554
>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
Length = 560
Score = 572 bits (1475), Expect = e-163
Identities = 296/442 (66%), Positives = 342/442 (77%), Gaps = 8/442 (1%)
Query: 22 KAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQEEKGD 81
+ + Q + LR E L E A+ +++ + L+ + + ++++ D
Sbjct: 111 RRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTD 170
Query: 82 VPKDTLDDLFPNEDE---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYE 138
K+ LDDLFPN+++ Q + Q GGYEIPARLRTLHNLVIQYASQGRYE
Sbjct: 171 STKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYE 230
Query: 139 VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLG 198
VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLG
Sbjct: 231 VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLG 290
Query: 199 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQ 258
KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQ
Sbjct: 291 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQ 350
Query: 259 NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR 318
NQGK EEVEYYY+RALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTR
Sbjct: 351 NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTR 410
Query: 319 AHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSL 378
AHE+EFGSV+ +NKPIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++L
Sbjct: 411 AHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNL 470
Query: 379 GALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGA 438
GALYRRQGK EAA TLE+ A R+RKQGLD + +V E+L D ++R SR+
Sbjct: 471 GALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVD 528
Query: 439 GPRSESDL---EDVGPTAEWNG 457
+ ES E+V + EWNG
Sbjct: 529 VVKYESGPDGGEEVSMSVEWNG 550
>gi|91825557 kinesin light chain 3 [Homo sapiens]
Length = 504
Score = 363 bits (933), Expect = e-100
Identities = 192/283 (67%), Positives = 216/283 (76%), Gaps = 2/283 (0%)
Query: 74 EAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYAS 133
E+Q+ + +D+L LFP+E+E+ P G + Q GGYEIPARLRTLHNLVIQYA
Sbjct: 161 ESQQSESPPRRDSLASLFPSEEEERKGPEAAGA-AAAQQGGYEIPARLRTLHNLVIQYAG 219
Query: 134 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR 193
QGRYEVAVPLC+QALEDLE++SGH HPDVATMLNILALVYRDQNKYKEA LL+DAL IR
Sbjct: 220 QGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIR 279
Query: 194 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNL 253
E+TLG +HPAVAATLNNLAVLYGKRG+Y+EAEPLC+RALEIREKVLG HPDVAKQL+NL
Sbjct: 280 EQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNL 339
Query: 254 ALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYK 313
ALLCQNQGK E+VE +Y RAL IY GP DPNVAKTKNNLAS YLKQ KYQ AE LYK
Sbjct: 340 ALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYK 399
Query: 314 EILTRAH-EKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYG 355
EIL + G+ N A R S K R+S G
Sbjct: 400 EILHKEDLPAPLGAPNTGTAGDAEQALRRSSSLSKIRESIRRG 442
Score = 165 bits (417), Expect = 1e-40
Identities = 168/546 (30%), Positives = 239/546 (43%), Gaps = 76/546 (13%)
Query: 10 EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGS----QERCILLRRSL 65
E+LS +E+V T+ V+QGLE LR EH L L AG+ +E+ ++ SL
Sbjct: 16 ERLSPEELVRQTRQVVQGLEALRAEHHGLAGHLAEALAGQGPAAGLEMLEEKQQVVSHSL 75
Query: 66 EAIELGLGEAQ------EEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPA 119
EAIELGLGEAQ G + + + +S A +V + E
Sbjct: 76 EAIELGLGEAQVLLALSAHVGALEAE-------KQRLRSQARRLAQENVWLREELEETQR 128
Query: 120 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKY 179
RLR V Q + R+ + +Q E P ++ ++ ++ K
Sbjct: 129 RLRASEESVAQLEEEKRHLEFLGQLRQYDPPAESQQSESPPRRDSLASLFP-SEEEERKG 187
Query: 180 KEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVL 239
EAA A + G + PA TL+NL + Y +G+Y+ A PLC++ALE E+
Sbjct: 188 PEAAG------AAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSS 241
Query: 240 GKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCY 299
G HPDVA L+ LAL+ ++Q K +E AL+I LGP+ P VA T NNLA Y
Sbjct: 242 GHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLY 301
Query: 300 LKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRD-SAPYGEYG 358
K+G+Y++AE L + L EK G+ + D + +++ K D Y
Sbjct: 302 GKRGRYREAEPLCQRAL-EIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARAL 360
Query: 359 SWYKAC-KVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVEL 417
S Y+A P V T +L + Y +Q K + A L E+
Sbjct: 361 SIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEEL-------------------YKEI 401
Query: 418 LKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALR 477
L D+ G P GD +LRRS S K+R+++R
Sbjct: 402 L-----------HKEDLPAPLG----------APNTGTAGDAEQALRRSSSLSKIRESIR 440
Query: 478 RSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLS-----DSRTLSS 532
R SE LV +L+G MKRA SLN LN V+ P PG S RTLS+
Sbjct: 441 RGSEKLVSRLRGEAAAGAAG--MKRAMSLNTLN--VDAPRAPGTQFPSWHLDKAPRTLSA 496
Query: 533 SSMDLS 538
S+ DLS
Sbjct: 497 STQDLS 502
>gi|19923891 kinesin-like 8 isoform c [Homo sapiens]
Length = 315
Score = 211 bits (537), Expect = 1e-54
Identities = 104/133 (78%), Positives = 117/133 (87%), Gaps = 2/133 (1%)
Query: 75 AQEEKGDVPKDTLDDLFPNEDEQSPAP--SPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 132
++E++GD KD+LDDLFPNE+E+ P+ S G G + Q GGYEIPARLRTLHNLVIQYA
Sbjct: 163 SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA 222
Query: 133 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 192
+QGRYEVAVPLCKQALEDLE+TSG HPDVATMLNILALVYRDQNKYKEAAHLLNDAL+I
Sbjct: 223 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI 282
Query: 193 REKTLGKDHPAVA 205
RE TLG DHPAV+
Sbjct: 283 RESTLGPDHPAVS 295
Score = 106 bits (264), Expect = 6e-23
Identities = 92/294 (31%), Positives = 138/294 (46%), Gaps = 21/294 (7%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
Query: 62 RRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSP------GGGDVSGQHGGY 115
RRS+E IELGL EAQ V L E E+ + + + G
Sbjct: 72 RRSMENIELGLSEAQ-----VMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGT 126
Query: 116 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
+ RL+ V Q + ++ + +Q ED + + L+ L + +
Sbjct: 127 Q--QRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDL---FPN 181
Query: 176 QNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIR 235
+ + + L A + G + PA TL+NL + Y +G+Y+ A PLCK+ALE
Sbjct: 182 EEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDL 241
Query: 236 EKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVA 289
E+ G+ HPDVA L+ LAL+ ++Q K +E + AL I + LGPD P V+
Sbjct: 242 ERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
Score = 35.0 bits (79), Expect = 0.18
Identities = 24/74 (32%), Positives = 34/74 (45%)
Query: 244 PDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQG 303
P + L NL + QG+ E ++ALE G P+VA N LA Y Q
Sbjct: 208 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQN 267
Query: 304 KYQDAETLYKEILT 317
KY++A L + L+
Sbjct: 268 KYKEAAHLLNDALS 281
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 146 bits (369), Expect = 4e-35
Identities = 108/308 (35%), Positives = 144/308 (46%), Gaps = 37/308 (12%)
Query: 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 177
P ++LH L Y ++ A L KQALE E G DHP A L LA +Y+ QN
Sbjct: 982 PRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHPYTARELEALATLYQKQN 1041
Query: 178 KYKEAAH------------------------LLNDALAIREKTLGKDHPAVAATLNNLAV 213
KY++A H L AL + E TLGKD P A TLN L V
Sbjct: 1042 KYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGV 1101
Query: 214 LYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRA 273
LY + + A+ KR+LE+RE+VLG HPD A+ L+NLA LC + + ++ E Y RA
Sbjct: 1102 LYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERA 1161
Query: 274 LEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKP 333
L+I L PD P++A T +LA Y K GK A LY E+ +K FG +
Sbjct: 1162 LDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLY-ELAVEIRQKSFGPKHPSVAT 1220
Query: 334 IWMHAEEREESKDKRRDSAPYGEYGSWYKACKV--DS-----PTVNTTLRSLGALYRRQG 386
++ K ++ P E +A K+ DS P V TL++L L G
Sbjct: 1221 ALVNLAVLYSQMKKHVEALPLYE-----RALKIYEDSLGRMHPRVGETLKNLAVLSYEGG 1275
Query: 387 KLEAAHTL 394
E A L
Sbjct: 1276 DFEKAAEL 1283
Score = 141 bits (355), Expect = 2e-33
Identities = 83/203 (40%), Positives = 111/203 (54%)
Query: 114 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 173
G + P RTL+ L + Y Q E A K++LE E+ G DHPD A LN LA +
Sbjct: 1086 GKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALC 1145
Query: 174 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 233
++ +Y +A L AL IR + L DHP++A T+ +LA+LY K GK +A PL + A+E
Sbjct: 1146 NEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVE 1205
Query: 234 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 293
IR+K G HP VA L NLA+L K E Y RAL+IY LG P V +T
Sbjct: 1206 IRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRVGETLK 1265
Query: 294 NLASCYLKQGKYQDAETLYKEIL 316
NLA + G ++ A LYK +
Sbjct: 1266 NLAVLSYEGGDFEKAAELYKRAM 1288
Score = 119 bits (299), Expect = 5e-27
Identities = 82/246 (33%), Positives = 120/246 (48%), Gaps = 25/246 (10%)
Query: 107 DVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVA------------------------VP 142
++S G + P R L L Y Q +YE A
Sbjct: 1013 EISENAYGADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFAL 1072
Query: 143 LCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHP 202
L ++AL+ E T G D PD A LN L ++Y QN + A L +L +RE+ LG DHP
Sbjct: 1073 LRRRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHP 1132
Query: 203 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGK 262
A +LNNLA L ++ +Y +AE L +RAL+IR + L HP +A + +LA+L + GK
Sbjct: 1133 DCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGK 1192
Query: 263 AEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEK 322
++ Y A+EI GP P+VA NLA Y + K+ +A LY+ L + +E
Sbjct: 1193 LDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERAL-KIYED 1251
Query: 323 EFGSVN 328
G ++
Sbjct: 1252 SLGRMH 1257
Score = 115 bits (287), Expect = 1e-25
Identities = 91/295 (30%), Positives = 130/295 (44%), Gaps = 66/295 (22%)
Query: 138 EVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 197
+ VPL +++LE E DHP VA L+ LA VY K+ A L AL I E
Sbjct: 961 QAIVPL-QRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAY 1019
Query: 198 GKDHPAVAATLNNLAVLYGKRGKYKEAEP------------------------LCKRALE 233
G DHP A L LA LY K+ KY++AE L +RAL+
Sbjct: 1020 GADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQ 1079
Query: 234 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 293
+ E LGK PD A+ L+ L +L Q E + + +R+LE+ LGPD P+ A++ N
Sbjct: 1080 LEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLN 1139
Query: 294 NLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAP 353
NLA+ ++ +Y AE LY E + D RR
Sbjct: 1140 NLAALCNEKKQYDKAEELY-----------------------------ERALDIRR---- 1166
Query: 354 YGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDP 408
+A D P++ T++ L LY++ GKL+ A L + A R++ P
Sbjct: 1167 --------RALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGP 1213
Score = 110 bits (274), Expect = 4e-24
Identities = 78/225 (34%), Positives = 120/225 (53%), Gaps = 13/225 (5%)
Query: 59 ILLRRSLEAIELGLGEAQEEKGDVPKD--TLDDL-----FPNEDEQSPAPSPGGGDVSGQ 111
+L RR+L+ EL LG+ D P + TL++L N E + ++ +
Sbjct: 1072 LLRRRALQLEELTLGK------DTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRER 1125
Query: 112 HGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILAL 171
G + P ++L+NL + +Y+ A L ++AL+ + DHP +A + LA+
Sbjct: 1126 VLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAI 1185
Query: 172 VYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRA 231
+Y+ K +A L A+ IR+K+ G HP+VA L NLAVLY + K+ EA PL +RA
Sbjct: 1186 LYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERA 1245
Query: 232 LEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 276
L+I E LG+ HP V + L NLA+L G E+ Y+RA+EI
Sbjct: 1246 LKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEI 1290
Score = 90.1 bits (222), Expect = 5e-18
Identities = 52/119 (43%), Positives = 72/119 (60%)
Query: 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 177
P+ T+ +L I Y G+ + AVPL + A+E +K+ G HP VAT L LA++Y
Sbjct: 1174 PSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMK 1233
Query: 178 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 236
K+ EA L AL I E +LG+ HP V TL NLAVL + G +++A L KRA+EI+E
Sbjct: 1234 KHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEIKE 1292
Score = 43.1 bits (100), Expect = 6e-04
Identities = 25/81 (30%), Positives = 44/81 (54%)
Query: 114 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 173
G + P+ L NL + Y+ ++ A+PL ++AL+ E + G HP V L LA++
Sbjct: 1212 GPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLS 1271
Query: 174 RDQNKYKEAAHLLNDALAIRE 194
+ +++AA L A+ I+E
Sbjct: 1272 YEGGDFEKAAELYKRAMEIKE 1292
>gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]
Length = 501
Score = 55.8 bits (133), Expect = 1e-07
Identities = 54/222 (24%), Positives = 101/222 (45%), Gaps = 39/222 (17%)
Query: 104 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 163
GGG + EI +L ++ YA+Q R E AV + + LE+
Sbjct: 289 GGGMKQEDNAIIEISLKLASI------YAAQNRQEFAVAGYEFCISTLEE---------- 332
Query: 164 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKY 221
K + L D +++ EK H + L+ A +L+ K+
Sbjct: 333 --------------KIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS- 375
Query: 222 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 281
+A+ + ++AL+I E++ G+ HP +S+LA QG+ +E Y +RA ++ A ++
Sbjct: 376 -QAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDL-ARQI 433
Query: 282 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 323
+ P + +NLA+ + + +Y A+ +Y+E L +A K+
Sbjct: 434 --NHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKK 473
>gi|87162455 hypothetical protein LOC23277 [Homo sapiens]
Length = 1309
Score = 55.1 bits (131), Expect = 2e-07
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 134 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR 193
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
Query: 194 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNL 253
E+ +G +HP +LA+ + A L RA + V G+ HP++A +N+
Sbjct: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
Query: 254 ALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA----- 308
L+ + + + AL + GP VA + + +A Y + +++ A
Sbjct: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
Query: 309 --ETLYKEILTRAHEK 322
T+YK L HEK
Sbjct: 1171 EGYTIYKTQLGEDHEK 1186
Score = 49.3 bits (116), Expect = 9e-06
Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 25/268 (9%)
Query: 114 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 173
G E P ++ +L + + + A+ L +A + G DHP++A + N + LV
Sbjct: 1055 GTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVL 1114
Query: 174 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 233
+Y + L +ALA+ K G VA + + +A +Y + +++ A K
Sbjct: 1115 HGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYT 1174
Query: 234 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 293
I + LG+ H + L L Q + R EIY + P + T
Sbjct: 1175 IYKTQLGEDHEKTKESSEYLKCLTQ------QAVALQRTMNEIYRNGSSANIPPLKFTAP 1228
Query: 294 NLASCYLKQG----------KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 343
++AS + +D E L E+ R H+ + S N D E
Sbjct: 1229 SMASVLEQLNVINGILFIPLSQKDLENLKAEV-ARRHQLQEASRNRDR-------AEEPM 1280
Query: 344 SKDKRRDSAPYGEYGSWYKACKVDSPTV 371
+ + AP G+ GS A K SP+V
Sbjct: 1281 ATEPAPAGAP-GDLGSQPPAAKDPSPSV 1307
Score = 42.7 bits (99), Expect = 8e-04
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 5/167 (2%)
Query: 135 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRE 194
G Y A+ ++A+ E+ G +HP+ LAL ++ A LL A +
Sbjct: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
Query: 195 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA 254
G+DHP +A NN+ ++ +Y + + AL + K G VA +A
Sbjct: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
Query: 255 LLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLK 301
+ +++ + + + IY T+LG D KTK +S YLK
Sbjct: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
>gi|18104962 amyloid beta precursor protein-binding protein 2 [Homo
sapiens]
Length = 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 13/191 (6%)
Query: 128 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 176
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
Query: 177 NKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 236
+EA L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
Query: 237 KVLGKFHPDVAKQLSNLALLCQ-NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 295
++LG+ +VA + +LA L + + E E Y R++ I G + L
Sbjct: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
Query: 296 ASCYLKQGKYQ 306
Y G Y+
Sbjct: 521 IKLYNSIGNYE 531
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 126 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR-DQNKYKEAAH 184
NL Y S +++ A + +A++ E+ G + +VA + LA +Y D N+Y+ A
Sbjct: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
Query: 185 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 223
L ++AI +K G+ + + L LY G Y++
Sbjct: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 53.5 bits (127), Expect = 5e-07
Identities = 48/157 (30%), Positives = 67/157 (42%), Gaps = 24/157 (15%)
Query: 160 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 219
P+ A + LA VY +Q A A+ ++ P NLA ++G
Sbjct: 246 PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------PHFPDAYCNLANALKEKG 297
Query: 220 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 279
EAE AL + P A L+NLA + + QG EE YR+ALE++
Sbjct: 298 SVAEAEDCYNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF-- 347
Query: 280 RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 316
P A +NLAS +QGK Q+A YKE +
Sbjct: 348 ------PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 378
Score = 53.1 bits (126), Expect = 6e-07
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 24/154 (15%)
Query: 126 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHL 185
NL Y QG ++A+ ++A+E P LA +++ EA
Sbjct: 254 NLACVYYEQGLIDLAIDTYRRAIEL--------QPHFPDAYCNLANALKEKGSVAEAEDC 305
Query: 186 LNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPD 245
N AL + P A +LNNLA + ++G +EA L ++ALE+ P+
Sbjct: 306 YNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEV--------FPE 349
Query: 246 VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 279
A SNLA + Q QGK +E +Y+ A+ I T
Sbjct: 350 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 383
Score = 41.2 bits (95), Expect = 0.002
Identities = 53/200 (26%), Positives = 81/200 (40%), Gaps = 32/200 (16%)
Query: 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 177
P +L+NL QG E AV L ++ALE P+ A + LA V + Q
Sbjct: 314 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQG 365
Query: 178 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
K +EA +A+ I P A +N+ + + A RA++I
Sbjct: 366 KLQEALMHYKEAIRI--------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI--- 414
Query: 238 VLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLAS 297
+P A SNLA + ++ G E YR AL +L PD P+ NLA
Sbjct: 415 -----NPAFADAHSNLASIHKDSGNIPEAIASYRTAL-----KLKPDFPD---AYCNLAH 461
Query: 298 CYLKQGKYQDAETLYKEILT 317
C + D + K++++
Sbjct: 462 CLQIVCDWTDYDERMKKLVS 481
Score = 37.7 bits (86), Expect = 0.027
Identities = 54/226 (23%), Positives = 92/226 (40%), Gaps = 32/226 (14%)
Query: 160 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 219
PD +L +L+ ++ + +AH LAI K +P +A +NL +Y +RG
Sbjct: 42 PDNTGVLLLLSSIHFQCRRLDRSAHF--STLAI------KQNPLLAEAYSNLGNVYKERG 93
Query: 220 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 279
+ +EA + AL ++ PD NLA G E Y AL+
Sbjct: 94 QLQEAIEHYRHALRLK--------PDFIDGYINLAAALVAAGDMEGAVQAYVSALQY--- 142
Query: 280 RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLY-KEILTRAH----EKEFGSVNGDNKPI 334
+P++ +++L + G+ ++A+ Y K I T+ + G V I
Sbjct: 143 -----NPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 197
Query: 335 WM--HAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSL 378
W+ H E+ + D A Y G+ K ++ V LR+L
Sbjct: 198 WLAIHHFEKAVTLDPNFLDA-YINLGNVLKEARIFDRAVAAYLRAL 242
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 53.5 bits (127), Expect = 5e-07
Identities = 48/157 (30%), Positives = 67/157 (42%), Gaps = 24/157 (15%)
Query: 160 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 219
P+ A + LA VY +Q A A+ ++ P NLA ++G
Sbjct: 256 PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------PHFPDAYCNLANALKEKG 307
Query: 220 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 279
EAE AL + P A L+NLA + + QG EE YR+ALE++
Sbjct: 308 SVAEAEDCYNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF-- 357
Query: 280 RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 316
P A +NLAS +QGK Q+A YKE +
Sbjct: 358 ------PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 388
Score = 53.1 bits (126), Expect = 6e-07
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 24/154 (15%)
Query: 126 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHL 185
NL Y QG ++A+ ++A+E P LA +++ EA
Sbjct: 264 NLACVYYEQGLIDLAIDTYRRAIEL--------QPHFPDAYCNLANALKEKGSVAEAEDC 315
Query: 186 LNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPD 245
N AL + P A +LNNLA + ++G +EA L ++ALE+ P+
Sbjct: 316 YNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEV--------FPE 359
Query: 246 VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 279
A SNLA + Q QGK +E +Y+ A+ I T
Sbjct: 360 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 393
Score = 41.2 bits (95), Expect = 0.002
Identities = 53/200 (26%), Positives = 81/200 (40%), Gaps = 32/200 (16%)
Query: 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 177
P +L+NL QG E AV L ++ALE P+ A + LA V + Q
Sbjct: 324 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQG 375
Query: 178 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
K +EA +A+ I P A +N+ + + A RA++I
Sbjct: 376 KLQEALMHYKEAIRI--------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI--- 424
Query: 238 VLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLAS 297
+P A SNLA + ++ G E YR AL +L PD P+ NLA
Sbjct: 425 -----NPAFADAHSNLASIHKDSGNIPEAIASYRTAL-----KLKPDFPD---AYCNLAH 471
Query: 298 CYLKQGKYQDAETLYKEILT 317
C + D + K++++
Sbjct: 472 CLQIVCDWTDYDERMKKLVS 491
Score = 37.7 bits (86), Expect = 0.027
Identities = 54/226 (23%), Positives = 92/226 (40%), Gaps = 32/226 (14%)
Query: 160 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 219
PD +L +L+ ++ + +AH LAI K +P +A +NL +Y +RG
Sbjct: 52 PDNTGVLLLLSSIHFQCRRLDRSAHF--STLAI------KQNPLLAEAYSNLGNVYKERG 103
Query: 220 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 279
+ +EA + AL ++ PD NLA G E Y AL+
Sbjct: 104 QLQEAIEHYRHALRLK--------PDFIDGYINLAAALVAAGDMEGAVQAYVSALQY--- 152
Query: 280 RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLY-KEILTRAH----EKEFGSVNGDNKPI 334
+P++ +++L + G+ ++A+ Y K I T+ + G V I
Sbjct: 153 -----NPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 207
Query: 335 WM--HAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSL 378
W+ H E+ + D A Y G+ K ++ V LR+L
Sbjct: 208 WLAIHHFEKAVTLDPNFLDA-YINLGNVLKEARIFDRAVAAYLRAL 252
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 49.7 bits (117), Expect = 7e-06
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 23/155 (14%)
Query: 169 LALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLC 228
L V + Q+K EA +AL R +A L NL +L + ++ EA
Sbjct: 499 LGNVLKSQSKISEAESAYRNALYYRSN--------MADMLYNLGLLLQENSRFAEALHYY 550
Query: 229 KRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNV 288
K A+ R P +A N ++ NQG+ EE + + EI L DP+
Sbjct: 551 KLAIGSR--------PTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENL--KDPHA 600
Query: 289 AKTK-----NNLASCYLKQGKYQDAETLYKEILTR 318
K+ NL Y +QG Y++A ++YKE + +
Sbjct: 601 HKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQK 635
Score = 40.4 bits (93), Expect = 0.004
Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 13/111 (11%)
Query: 124 LHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAA 183
L+NL Y QG YE A+ + K+A++ + + ++ N++ Y +K EA
Sbjct: 609 LYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQ-----SLYNMMGEAYMRLSKLPEAE 663
Query: 184 HLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 234
H ++L R KT DH T L L G++ EAE L +A+E+
Sbjct: 664 HWYMESL--RSKT---DHIPAHLTYGKLLALTGRK---SEAEKLFLKAIEL 706
Score = 30.4 bits (67), Expect = 4.3
Identities = 43/186 (23%), Positives = 68/186 (36%), Gaps = 27/186 (14%)
Query: 211 LAVLYG-----KRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEE 265
L V YG + G ++ E L + +++ AK NL + ++Q K E
Sbjct: 462 LIVFYGLKTAIRNGDWQNEEMLYRSGIKVNP----------AKAWGNLGNVLKSQSKISE 511
Query: 266 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFG 325
E YR AL + N+A NL + ++ +A YK L
Sbjct: 512 AESAYRNALYYRS--------NMADMLYNLGLLLQENSRFAEALHYYK--LAIGSRPTLA 561
Query: 326 SVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQ 385
S + I M+ EE++ + + K +V + L +LG LY Q
Sbjct: 562 SAYLNTGIILMNQGRTEEARRTFLKCSEIPDEN--LKDPHAHKSSVTSCLYNLGKLYHEQ 619
Query: 386 GKLEAA 391
G E A
Sbjct: 620 GHYEEA 625
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 46.2 bits (108), Expect = 8e-05
Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 33/189 (17%)
Query: 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 177
P + + N Y +G Y LC++A+E + + + D+ +A + Y +
Sbjct: 256 PTNMTYITNQAAVYFEKGDYNKCRELCEKAIE-VGRENREDYRQIAKAYARIGNSYFKEE 314
Query: 178 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
KYK+A H N +LA P V K ++AE + K ++
Sbjct: 315 KYKDAIHFYNKSLAEHRT------PDVLK-------------KCQQAEKILK-----EQE 350
Query: 238 VLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLAS 297
L +PD+A + N C +G + +Y A++ +P AK +N A+
Sbjct: 351 RLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIK--------RNPKDAKLYSNRAA 402
Query: 298 CYLKQGKYQ 306
CY K ++Q
Sbjct: 403 CYTKLLEFQ 411
Score = 37.4 bits (85), Expect = 0.035
Identities = 34/170 (20%), Positives = 66/170 (38%), Gaps = 39/170 (22%)
Query: 187 NDALAIREKTLGKD--------------------HPAVAATLNNLAVLYGKRGKYKEAEP 226
N A++EK LG D P + N A +Y ++G Y +
Sbjct: 221 NKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRE 280
Query: 227 LCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT------- 279
LC++A+E+ + + +AK + + + K ++ ++Y ++L + T
Sbjct: 281 LCEKAIEVGRENREDYR-QIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKC 339
Query: 280 -----------RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR 318
RL +P++A + N + ++G Y A Y E + R
Sbjct: 340 QQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKR 389
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 45.1 bits (105), Expect = 2e-04
Identities = 44/171 (25%), Positives = 72/171 (42%), Gaps = 24/171 (14%)
Query: 159 HPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 218
HP L L + + Q K +EA LL D++ K P A ++LA L ++
Sbjct: 436 HPQHNRALFNLGNLLKSQEKKEEAITLLKDSI--------KYGPEFADAYSSLASLLAEQ 487
Query: 219 GKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYA 278
++KEAE + + + K PD + +N + + G E+ +Y++A+++
Sbjct: 488 ERFKEAEEIYQTGI--------KNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKL-- 537
Query: 279 TRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNG 329
P+ NL Y G+ AE YK L AH+ E S G
Sbjct: 538 ------SPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLG 582
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/197 (23%), Positives = 83/197 (42%), Gaps = 33/197 (16%)
Query: 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 177
P R L NL SQ + E A+ L K +++ P+ A + LA + +Q
Sbjct: 437 PQHNRALFNLGNLLKSQEKKEEAITLLKDSIKY--------GPEFADAYSSLASLLAEQE 488
Query: 178 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
++KEA + + K+ P + NN V G ++A ++A+
Sbjct: 489 RFKEAEEIYQTGI--------KNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAI----- 535
Query: 238 VLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLAS 297
K P + NL L ++ G+ E +Y+RAL++ + A+ + L +
Sbjct: 536 ---KLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQV---------AHKAEILSPLGA 583
Query: 298 CYLKQGKYQDAETLYKE 314
Y G+Y++A +Y+E
Sbjct: 584 LYYNTGRYEEALQIYQE 600
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 27/140 (19%)
Query: 174 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 233
+DQ + KEA + AL + +P A+ LNNL L EA+ +RAL+
Sbjct: 386 KDQGRNKEAIYHYRTALKL--------YPRHASALNNLGTLTRDTA---EAKMYYQRALQ 434
Query: 234 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 293
+ HP + L NL L ++Q K EE + +++ P A +
Sbjct: 435 L--------HPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKY--------GPEFADAYS 478
Query: 294 NLASCYLKQGKYQDAETLYK 313
+LAS +Q ++++AE +Y+
Sbjct: 479 SLASLLAEQERFKEAEEIYQ 498
Score = 35.0 bits (79), Expect = 0.18
Identities = 43/207 (20%), Positives = 80/207 (38%), Gaps = 46/207 (22%)
Query: 116 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL-----------------------EDLE 152
++ + L L Y + GRYE A+ + ++A ++ E
Sbjct: 570 QVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAE 629
Query: 153 KTSGH---DHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLN 209
K + H + +L+ +Y Q + +A ++ AL ++ K P V
Sbjct: 630 KMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKD-----PKV----- 679
Query: 210 NLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYY 269
++ L+ +G + L +A E +V + +PD A+ N+ + +GK Y
Sbjct: 680 -ISELFFTKGNQLREQNLLDKAFE-SYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAY 737
Query: 270 YRRALEIYATRLGPDDPNVAKTKNNLA 296
Y RAL++ P+ K NLA
Sbjct: 738 YERALQLV--------PDSKLLKENLA 756
Score = 34.3 bits (77), Expect = 0.30
Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 14/121 (11%)
Query: 244 PDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQG 303
P AK N A ++QG+ +E Y+YR AL++Y P A NNL +
Sbjct: 372 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLY--------PRHASALNNLGTLTRDTA 423
Query: 304 KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYG-EYGSWYK 362
+A+ Y+ L + N N + E++EE+ +DS YG E+ Y
Sbjct: 424 ---EAKMYYQRALQLHPQHNRALFNLGN--LLKSQEKKEEAITLLKDSIKYGPEFADAYS 478
Query: 363 A 363
+
Sbjct: 479 S 479
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 42.4 bits (98), Expect = 0.001
Identities = 65/298 (21%), Positives = 112/298 (37%), Gaps = 54/298 (18%)
Query: 106 GDVSGQHGGYEIPARLRTLHNLVIQ----YASQGR--------------YEVAVPLCKQA 147
G + G Y+ +L H + Q YA+QGR Y+ AV +Q
Sbjct: 481 GIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQE 540
Query: 148 LEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAAT 207
L+ + + D A+ LA+ Y+ + A + L I + +D + A
Sbjct: 541 LQISMEVN--DRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIAREL--RDIQSEARA 596
Query: 208 LNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVE 267
L+NL + RG+Y +A P ++ L + PD+ + + +C N G A
Sbjct: 597 LSNLGNFHCSRGEYVQAAPYYEQYLRLA--------PDL-QDMEGEGKVCHNLGYAHYCL 647
Query: 268 YYYRRALEIYATRLG-----PDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE- 321
Y+ A++ Y L D + AK NL + + AE K +L+ A
Sbjct: 648 GNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSL 707
Query: 322 -------KEFGS----------VNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYK 362
+ G+ +NG K + KD+R +++ Y G+ Y+
Sbjct: 708 NNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYR 765
Score = 40.8 bits (94), Expect = 0.003
Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 7/153 (4%)
Query: 169 LALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLC 228
L YR KY +A L + ++ D P +LA +Y GKY A
Sbjct: 760 LGTAYRMIQKYDKALGYHTQELEVYQEL--SDLPGECRAHGHLAAVYMALGKYTMAFKCY 817
Query: 229 KRALEIREKVLGKFHPDVAKQL-SNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDP- 286
+ L++ +K+ P + Q+ N+ + N EE Y+ + L + G +
Sbjct: 818 EEQLDLGQKLKD---PSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVL 874
Query: 287 NVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 319
+ + NL CY G Y++A Y++ L+ A
Sbjct: 875 DRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVA 907
Score = 33.5 bits (75), Expect = 0.51
Identities = 48/207 (23%), Positives = 80/207 (38%), Gaps = 32/207 (15%)
Query: 122 RTLHNLVIQYASQGRYEVAVPLCKQAL---EDLEKTSGHDHPDVATMLNILALVYRDQNK 178
+ HNL + G Y+ AV +Q L +DL HD A L L ++
Sbjct: 635 KVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDL-----HDKLSQAKAYCNLGLAFKALLN 689
Query: 179 YKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKR----ALEI 234
+ +A L++ + + A L NL ++ +CK+ A++
Sbjct: 690 FSKAEECQKYLLSLAQSL--NNSQAKFRALGNLGDIF-----------ICKKDINGAIKF 736
Query: 235 REKVLGKFHPDVAKQLSNLALLCQNQG-----KAEEVEYYYRRALEIYATRLGPDDPNVA 289
E+ LG H ++L A K ++ Y+ + LE+Y D P
Sbjct: 737 YEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQEL--SDLPGEC 794
Query: 290 KTKNNLASCYLKQGKYQDAETLYKEIL 316
+ +LA+ Y+ GKY A Y+E L
Sbjct: 795 RAHGHLAAVYMALGKYTMAFKCYEEQL 821
Score = 32.7 bits (73), Expect = 0.87
Identities = 36/141 (25%), Positives = 57/141 (40%), Gaps = 9/141 (6%)
Query: 186 LNDALAIREKTLG-----KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLG 240
L A E+ LG KD A +NL +++ +G Y A L K L I +++
Sbjct: 450 LERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQEL-- 507
Query: 241 KFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYL 300
+ + N+ G ++ Y+R+ L+I + D + A T NLA Y
Sbjct: 508 SDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQI--SMEVNDRASQASTHGNLAVAYQ 565
Query: 301 KQGKYQDAETLYKEILTRAHE 321
G + A Y+ L A E
Sbjct: 566 ALGAHDRALQHYQNHLNIARE 586
>gi|116089276 tetratricopeptide repeat domain 23-like [Homo sapiens]
Length = 361
Score = 40.8 bits (94), Expect = 0.003
Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 10/136 (7%)
Query: 182 AAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGK-------RGKYKEAEPLCKRALEI 234
A H LN ALA EK +G A ++L LY + R + +A ++A +
Sbjct: 225 AIHRLNLALAYFEKAIGDVIAAKGDRTSDLISLYEEAAQIEQLRRNHNQAIQYLQQAHSV 284
Query: 235 REKVLGKFHPDVAKQLSNLALLCQNQGKAEE---VEYYYRRALEIYATRLGPDDPNVAKT 291
+ + P A+ + LA G+A+ VE Y+ R++ Y LG +D T
Sbjct: 285 CVSLFTEVSPKTAEMSALLAKAYAMSGEAQHRDAVEIYFIRSINAYRATLGSEDFETLST 344
Query: 292 KNNLASCYLKQGKYQD 307
++ G+ QD
Sbjct: 345 TEEFCKWLVQNGEKQD 360
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 38.5 bits (88), Expect = 0.016
Identities = 34/123 (27%), Positives = 49/123 (39%), Gaps = 24/123 (19%)
Query: 179 YKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKV 238
++ A H A+ + +PA A N A Y K G Y A C+RA+ I
Sbjct: 107 FEAAVHFYGKAIEL--------NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICI---- 154
Query: 239 LGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASC 298
P +K + L + K E YY++ALE+ DP+ K+NL
Sbjct: 155 ----DPAYSKAYGRMGLALSSLNKHVEAVAYYKKALEL--------DPDNETYKSNLKIA 202
Query: 299 YLK 301
LK
Sbjct: 203 ELK 205
>gi|17864094 feminization 1 homolog a [Homo sapiens]
Length = 617
Score = 38.5 bits (88), Expect = 0.016
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 168 ILALVY-RDQNKYKEAAHLLND-------ALAIREKTLGKDHPAVAATLNNLAVLYGKRG 219
I+A Y ++ N +E L+ D AL IRE+ LG HP + + +Y G
Sbjct: 293 IMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSG 352
Query: 220 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALL 256
+K L K AL++++ L P A L + A L
Sbjct: 353 NFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAEL 389
Score = 36.6 bits (83), Expect = 0.061
Identities = 21/70 (30%), Positives = 33/70 (47%)
Query: 146 QALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVA 205
QAL E+ G HPD + + VY D +K +L AL +++ L P A
Sbjct: 321 QALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTA 380
Query: 206 ATLNNLAVLY 215
++L + A L+
Sbjct: 381 SSLLSFAELF 390
Score = 33.9 bits (76), Expect = 0.39
Identities = 19/81 (23%), Positives = 38/81 (46%)
Query: 219 GKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYA 278
G + + + +AL IRE++LG HPD + + + + G + ++ AL++
Sbjct: 310 GLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQ 369
Query: 279 TRLGPDDPNVAKTKNNLASCY 299
+ L P P A + + A +
Sbjct: 370 SNLDPLSPMTASSLLSFAELF 390
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 37.4 bits (85), Expect = 0.035
Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 16/122 (13%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAP--LVAPEA-GEAEPGSQERCILLRR 63
P E + E + ++G+E E A P + PEA GEA+P S+ ++
Sbjct: 2191 PESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250
Query: 64 SLEAIELGLG---EAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPAR 120
+ LG G EA E VP ED +P PSPGG + G P+
Sbjct: 2251 GSPQVSLGDGQSEEASESSSPVP----------EDRPTPPPSPGGDTPHQRPGSQTGPSS 2300
Query: 121 LR 122
R
Sbjct: 2301 SR 2302
>gi|118766328 transmembrane and tetratricopeptide repeat containing
4 isoform 2 [Homo sapiens]
Length = 741
Score = 37.4 bits (85), Expect = 0.035
Identities = 45/188 (23%), Positives = 77/188 (40%), Gaps = 32/188 (17%)
Query: 126 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHL 185
NL I S R+E A + A++ K +PD L L Y D N++ +A +
Sbjct: 555 NLGIVQNSLKRFEAAEQSYRTAIKHRRK-----YPDCYYNLGRL---YADLNRHVDALNA 606
Query: 186 LNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPD 245
+A ++ P + NN+ +L G +AE + + ALE+ P+
Sbjct: 607 WRNATVLK--------PEHSLAWNNMIILLDNTGNLAQAEAVGREALEL--------IPN 650
Query: 246 VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKY 305
+ +LA + K +E E + +A++ +PN A NLA Y + G
Sbjct: 651 DHSLMFSLANVLGKSQKYKESEALFLKAIKA--------NPNAASYHGNLAVLYHRWGHL 702
Query: 306 QDAETLYK 313
A+ Y+
Sbjct: 703 DLAKKHYE 710
Score = 36.6 bits (83), Expect = 0.061
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 16/85 (18%)
Query: 210 NLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYY 269
+LA + GK KYKE+E L +A+ K +P+ A NLA+L G + + +
Sbjct: 657 SLANVLGKSQKYKESEALFLKAI--------KANPNAASYHGNLAVLYHRWGHLDLAKKH 708
Query: 270 YRRALEIYATRLGPDDPNVAKTKNN 294
Y +L++ DP + TK N
Sbjct: 709 YEISLQL--------DPTASGTKEN 725
Score = 33.1 bits (74), Expect = 0.67
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 201 HPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQ 260
+P +NNL + +R + +EAE L A++I+ PD A NL ++ +
Sbjct: 512 NPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQ--------PDFAAAWMNLGIVQNSL 563
Query: 261 GKAEEVEYYYRRALE 275
+ E E YR A++
Sbjct: 564 KRFEAAEQSYRTAIK 578
>gi|118766330 transmembrane and tetratricopeptide repeat containing
4 isoform 1 [Homo sapiens]
Length = 760
Score = 37.4 bits (85), Expect = 0.035
Identities = 45/188 (23%), Positives = 77/188 (40%), Gaps = 32/188 (17%)
Query: 126 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHL 185
NL I S R+E A + A++ K +PD L L Y D N++ +A +
Sbjct: 574 NLGIVQNSLKRFEAAEQSYRTAIKHRRK-----YPDCYYNLGRL---YADLNRHVDALNA 625
Query: 186 LNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPD 245
+A ++ P + NN+ +L G +AE + + ALE+ P+
Sbjct: 626 WRNATVLK--------PEHSLAWNNMIILLDNTGNLAQAEAVGREALEL--------IPN 669
Query: 246 VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKY 305
+ +LA + K +E E + +A++ +PN A NLA Y + G
Sbjct: 670 DHSLMFSLANVLGKSQKYKESEALFLKAIKA--------NPNAASYHGNLAVLYHRWGHL 721
Query: 306 QDAETLYK 313
A+ Y+
Sbjct: 722 DLAKKHYE 729
Score = 36.6 bits (83), Expect = 0.061
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 16/85 (18%)
Query: 210 NLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYY 269
+LA + GK KYKE+E L +A+ K +P+ A NLA+L G + + +
Sbjct: 676 SLANVLGKSQKYKESEALFLKAI--------KANPNAASYHGNLAVLYHRWGHLDLAKKH 727
Query: 270 YRRALEIYATRLGPDDPNVAKTKNN 294
Y +L++ DP + TK N
Sbjct: 728 YEISLQL--------DPTASGTKEN 744
Score = 33.1 bits (74), Expect = 0.67
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 201 HPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQ 260
+P +NNL + +R + +EAE L A++I+ PD A NL ++ +
Sbjct: 531 NPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQ--------PDFAAAWMNLGIVQNSL 582
Query: 261 GKAEEVEYYYRRALE 275
+ E E YR A++
Sbjct: 583 KRFEAAEQSYRTAIK 597
>gi|24308163 fem-1 homolog a [Homo sapiens]
Length = 669
Score = 37.0 bits (84), Expect = 0.046
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 8/97 (8%)
Query: 168 ILALVY-RDQNKYKEAAHLLND-------ALAIREKTLGKDHPAVAATLNNLAVLYGKRG 219
+LA Y R+ N +E L+ D AL IRE+ LG HP + + +Y G
Sbjct: 345 VLAYDYSREVNTTEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSG 404
Query: 220 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALL 256
++ L K AL++++ L P A + A L
Sbjct: 405 NFERCIRLWKYALDMQQSNLEPLSPMTASSFLSFAEL 441
Score = 33.9 bits (76), Expect = 0.39
Identities = 19/70 (27%), Positives = 34/70 (48%)
Query: 230 RALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVA 289
+AL IRE++LG HPD + + + + G E ++ AL++ + L P P A
Sbjct: 373 QALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQSNLEPLSPMTA 432
Query: 290 KTKNNLASCY 299
+ + A +
Sbjct: 433 SSFLSFAELF 442
Score = 32.7 bits (73), Expect = 0.87
Identities = 19/70 (27%), Positives = 31/70 (44%)
Query: 146 QALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVA 205
QAL E+ G HPD + + VY D ++ L AL +++ L P A
Sbjct: 373 QALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQSNLEPLSPMTA 432
Query: 206 ATLNNLAVLY 215
++ + A L+
Sbjct: 433 SSFLSFAELF 442
>gi|239755782 PREDICTED: hypothetical protein XP_002344710 [Homo
sapiens]
Length = 76
Score = 35.8 bits (81), Expect = 0.10
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 13/75 (17%)
Query: 438 AGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPN 497
AGPR + E +GS S RR GS G+L +SS+ L ++GG PQE P
Sbjct: 8 AGPRRQRGPEGA------RREGSDSPRR-GSVGELAPEPNKSSQRLAHPVEGGRPQESPG 60
Query: 498 ------PRMKRASSL 506
PR+ R +L
Sbjct: 61 WGGPAPPRLPRRPNL 75
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,396,115
Number of Sequences: 37866
Number of extensions: 1121810
Number of successful extensions: 3768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 3382
Number of HSP's gapped (non-prelim): 252
length of query: 545
length of database: 18,247,518
effective HSP length: 107
effective length of query: 438
effective length of database: 14,195,856
effective search space: 6217784928
effective search space used: 6217784928
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.