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Search of human proteins with 195976769
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195976769 dysferlin isoform 6 [Homo sapiens]
(2102 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195976769 dysferlin isoform 6 [Homo sapiens] 4326 0.0
gi|195976773 dysferlin isoform 5 [Homo sapiens] 4289 0.0
gi|195976758 dysferlin isoform 11 [Homo sapiens] 4276 0.0
gi|195976821 dysferlin isoform 2 [Homo sapiens] 4273 0.0
gi|195976779 dysferlin isoform 1 [Homo sapiens] 4273 0.0
gi|195976766 dysferlin isoform 7 [Homo sapiens] 4256 0.0
gi|195976756 dysferlin isoform 10 [Homo sapiens] 4238 0.0
gi|195976777 dysferlin isoform 3 [Homo sapiens] 4235 0.0
gi|4503431 dysferlin isoform 8 [Homo sapiens] 4222 0.0
gi|195976764 dysferlin isoform 14 [Homo sapiens] 4222 0.0
gi|195976775 dysferlin isoform 4 [Homo sapiens] 4219 0.0
gi|195976760 dysferlin isoform 12 [Homo sapiens] 4205 0.0
gi|195976754 dysferlin isoform 9 [Homo sapiens] 4184 0.0
gi|195976762 dysferlin isoform 13 [Homo sapiens] 4168 0.0
gi|7305053 myoferlin isoform a [Homo sapiens] 2381 0.0
gi|19718759 myoferlin isoform b [Homo sapiens] 2379 0.0
gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens] 1438 0.0
gi|35493868 otoferlin isoform b [Homo sapiens] 726 0.0
gi|35493853 otoferlin isoform c [Homo sapiens] 723 0.0
gi|34740331 otoferlin isoform a [Homo sapiens] 723 0.0
gi|119120884 fer-1-like 6 [Homo sapiens] 720 0.0
gi|35493860 otoferlin isoform d [Homo sapiens] 719 0.0
gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens] 711 0.0
gi|4759026 RAS protein activator like 1 [Homo sapiens] 65 5e-10
gi|14149680 extended synaptotagmin-like protein 1 [Homo sapiens] 57 2e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 54 1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 54 1e-06
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 54 2e-06
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 54 2e-06
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva... 53 3e-06
>gi|195976769 dysferlin isoform 6 [Homo sapiens]
Length = 2102
Score = 4326 bits (11221), Expect = 0.0
Identities = 2102/2102 (100%), Positives = 2102/2102 (100%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
Query: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
Query: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
Query: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
Query: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
Query: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
Query: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
Query: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
Query: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
Query: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
Query: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
Query: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
Query: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
Query: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
Query: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW
Sbjct: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
Query: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
Query: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
Query: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
Query: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
Query: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
Query: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
Query: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
Query: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
Query: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
Query: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
Query: 2101 FS 2102
FS
Sbjct: 2101 FS 2102
>gi|195976773 dysferlin isoform 5 [Homo sapiens]
Length = 2088
Score = 4289 bits (11123), Expect = 0.0
Identities = 2087/2102 (99%), Positives = 2088/2102 (99%), Gaps = 14/2102 (0%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
Query: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 526
Query: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 527 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 586
Query: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 587 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 646
Query: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 647 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 706
Query: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 707 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 766
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826
Query: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 827 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 886
Query: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 887 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 946
Query: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 947 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1006
Query: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1007 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1066
Query: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1067 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1126
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1246
Query: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1247 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1306
Query: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1307 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1366
Query: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1367 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1426
Query: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW
Sbjct: 1427 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1486
Query: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1487 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1546
Query: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1547 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1606
Query: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1607 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1666
Query: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1667 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1726
Query: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1727 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1786
Query: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1787 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1846
Query: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1847 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1906
Query: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1907 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1966
Query: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1967 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2026
Query: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2027 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2086
Query: 2101 FS 2102
FS
Sbjct: 2087 FS 2088
>gi|195976758 dysferlin isoform 11 [Homo sapiens]
Length = 2101
Score = 4276 bits (11089), Expect = 0.0
Identities = 2081/2102 (99%), Positives = 2085/2102 (99%), Gaps = 1/2102 (0%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
Query: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539
Query: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599
Query: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659
Query: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 719
Query: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 720 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 779
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839
Query: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 840 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 899
Query: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 900 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 959
Query: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 960 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1019
Query: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1020 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1079
Query: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1080 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1139
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1259
Query: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1260 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1319
Query: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1320 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1379
Query: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1380 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1439
Query: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW
Sbjct: 1440 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1499
Query: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1500 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1559
Query: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1560 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1619
Query: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1620 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1679
Query: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1680 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1739
Query: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1740 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1799
Query: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1800 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1859
Query: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1860 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1919
Query: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1920 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1979
Query: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1980 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2039
Query: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2040 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2099
Query: 2101 FS 2102
FS
Sbjct: 2100 FS 2101
>gi|195976821 dysferlin isoform 2 [Homo sapiens]
Length = 2081
Score = 4273 bits (11081), Expect = 0.0
Identities = 2081/2102 (99%), Positives = 2081/2102 (99%), Gaps = 21/2102 (0%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
Query: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
Query: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
Query: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
Query: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
Query: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
Query: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
Query: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
Query: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
Query: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
Query: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
Query: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
Query: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
Query: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
Query: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWW
Sbjct: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1479
Query: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1480 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1539
Query: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1540 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1599
Query: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1600 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1659
Query: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1660 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1719
Query: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1720 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1779
Query: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1780 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1839
Query: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1840 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1899
Query: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1900 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1959
Query: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1960 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2019
Query: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2020 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2079
Query: 2101 FS 2102
FS
Sbjct: 2080 FS 2081
>gi|195976779 dysferlin isoform 1 [Homo sapiens]
Length = 2119
Score = 4273 bits (11081), Expect = 0.0
Identities = 2087/2133 (97%), Positives = 2088/2133 (97%), Gaps = 45/2133 (2%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
Query: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
Query: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
Query: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
Query: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
Query: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
Query: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
Query: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
Query: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
Query: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
Query: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
Query: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
Query: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
Query: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
Query: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
Query: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
Query: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
Query: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529
IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1487 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1546
Query: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1547 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1606
Query: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1607 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1666
Query: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1667 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1726
Query: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1727 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1786
Query: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1787 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1846
Query: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1847 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1906
Query: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1907 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1966
Query: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1967 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2026
Query: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2027 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2086
Query: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2087 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2119
>gi|195976766 dysferlin isoform 7 [Homo sapiens]
Length = 2112
Score = 4256 bits (11039), Expect = 0.0
Identities = 2081/2133 (97%), Positives = 2081/2133 (97%), Gaps = 52/2133 (2%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
Query: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 541 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
Query: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 601 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
Query: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 661 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
Query: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 721 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
Query: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 781 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
Query: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 841 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
Query: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 901 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
Query: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 961 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
Query: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
Query: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
Query: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
Query: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
Query: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
Query: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
Query: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
Query: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
Query: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529
IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539
Query: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599
Query: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659
Query: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719
Query: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779
Query: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839
Query: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899
Query: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959
Query: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019
Query: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079
Query: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112
>gi|195976756 dysferlin isoform 10 [Homo sapiens]
Length = 2087
Score = 4238 bits (10991), Expect = 0.0
Identities = 2066/2102 (98%), Positives = 2071/2102 (98%), Gaps = 15/2102 (0%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
Query: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 480 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 525
Query: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 526 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 585
Query: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 586 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 645
Query: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 646 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 705
Query: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 706 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 765
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 766 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 825
Query: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 826 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 885
Query: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 886 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 945
Query: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 946 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1005
Query: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1006 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1065
Query: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1066 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1125
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1126 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1185
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1186 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1245
Query: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1246 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1305
Query: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1306 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1365
Query: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1366 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1425
Query: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW
Sbjct: 1426 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1485
Query: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1486 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1545
Query: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1546 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1605
Query: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1606 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1665
Query: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1666 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1725
Query: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1726 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1785
Query: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1786 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1845
Query: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1846 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1905
Query: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1906 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1965
Query: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1966 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2025
Query: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2026 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2085
Query: 2101 FS 2102
FS
Sbjct: 2086 FS 2087
>gi|195976777 dysferlin isoform 3 [Homo sapiens]
Length = 2067
Score = 4235 bits (10983), Expect = 0.0
Identities = 2066/2102 (98%), Positives = 2067/2102 (98%), Gaps = 35/2102 (1%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
Query: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 526
Query: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 527 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 586
Query: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 587 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 646
Query: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 647 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 706
Query: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 707 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 766
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826
Query: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 827 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 886
Query: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 887 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 946
Query: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 947 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1006
Query: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1007 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1066
Query: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1067 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1126
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1246
Query: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1247 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1306
Query: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1307 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1366
Query: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1367 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1426
Query: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWW
Sbjct: 1427 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1465
Query: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1466 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1525
Query: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1526 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1585
Query: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1586 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1645
Query: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1646 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1705
Query: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1706 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1765
Query: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1766 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1825
Query: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1826 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1885
Query: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1886 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1945
Query: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1946 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2005
Query: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2006 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2065
Query: 2101 FS 2102
FS
Sbjct: 2066 FS 2067
>gi|4503431 dysferlin isoform 8 [Homo sapiens]
Length = 2080
Score = 4222 bits (10949), Expect = 0.0
Identities = 2060/2102 (98%), Positives = 2064/2102 (98%), Gaps = 22/2102 (1%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
Query: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539
Query: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599
Query: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659
Query: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 719
Query: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 720 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 779
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839
Query: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 840 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 899
Query: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 900 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 959
Query: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 960 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1019
Query: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1020 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1079
Query: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1080 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1139
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1259
Query: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1260 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1319
Query: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1320 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1379
Query: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1380 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1439
Query: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWW
Sbjct: 1440 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1478
Query: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1479 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1538
Query: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1539 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1598
Query: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1599 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1658
Query: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1659 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1718
Query: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1719 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1778
Query: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1779 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1838
Query: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1839 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1898
Query: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1899 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1958
Query: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1959 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2018
Query: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2019 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2078
Query: 2101 FS 2102
FS
Sbjct: 2079 FS 2080
>gi|195976764 dysferlin isoform 14 [Homo sapiens]
Length = 2118
Score = 4222 bits (10949), Expect = 0.0
Identities = 2066/2133 (96%), Positives = 2071/2133 (97%), Gaps = 46/2133 (2%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 525
Query: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 526 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 585
Query: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 586 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 645
Query: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 646 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 705
Query: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 706 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765
Query: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 766 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825
Query: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 826 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885
Query: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 886 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 945
Query: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 946 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1005
Query: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1006 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1065
Query: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1066 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1125
Query: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1126 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1185
Query: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1186 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1245
Query: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1246 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1305
Query: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1306 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1365
Query: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1366 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1425
Query: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1426 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1485
Query: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529
IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1486 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1545
Query: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1546 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1605
Query: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1606 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1665
Query: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1666 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1725
Query: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1726 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1785
Query: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1786 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1845
Query: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1846 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1905
Query: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1906 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1965
Query: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1966 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2025
Query: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2026 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2085
Query: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2086 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2118
>gi|195976775 dysferlin isoform 4 [Homo sapiens]
Length = 2098
Score = 4219 bits (10941), Expect = 0.0
Identities = 2066/2133 (96%), Positives = 2067/2133 (96%), Gaps = 66/2133 (3%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
Query: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
Query: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
Query: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
Query: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
Query: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
Query: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
Query: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
Query: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
Query: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
Query: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
Query: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
Query: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
Query: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
Query: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
Query: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
Query: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
Query: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529
IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1487 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1525
Query: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1526 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1585
Query: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1586 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1645
Query: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1646 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1705
Query: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1706 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1765
Query: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1766 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1825
Query: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1826 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1885
Query: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1886 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1945
Query: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1946 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2005
Query: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2006 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2065
Query: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2066 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
>gi|195976760 dysferlin isoform 12 [Homo sapiens]
Length = 2111
Score = 4205 bits (10907), Expect = 0.0
Identities = 2060/2133 (96%), Positives = 2064/2133 (96%), Gaps = 53/2133 (2%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 539
Query: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 540 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 599
Query: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 600 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 659
Query: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 660 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 719
Query: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 720 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 779
Query: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 780 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 839
Query: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 840 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 899
Query: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 900 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 959
Query: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 960 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1019
Query: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1020 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1079
Query: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1080 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1139
Query: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1140 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1199
Query: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1200 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1259
Query: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1260 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1319
Query: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1320 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1379
Query: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1380 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1439
Query: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1440 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1499
Query: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529
IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1500 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1538
Query: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1539 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1598
Query: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1599 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1658
Query: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1659 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1718
Query: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1719 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1778
Query: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1779 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1838
Query: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1839 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1898
Query: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1899 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1958
Query: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1959 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2018
Query: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2019 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2078
Query: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2079 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2111
>gi|195976754 dysferlin isoform 9 [Homo sapiens]
Length = 2066
Score = 4184 bits (10851), Expect = 0.0
Identities = 2045/2102 (97%), Positives = 2050/2102 (97%), Gaps = 36/2102 (1%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
Query: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 480 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 525
Query: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 526 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 585
Query: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 586 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 645
Query: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 646 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 705
Query: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 706 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 765
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 766 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 825
Query: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 826 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 885
Query: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 886 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 945
Query: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 946 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1005
Query: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1006 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1065
Query: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1066 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1125
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1126 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1185
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1186 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1245
Query: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1246 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1305
Query: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1306 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1365
Query: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1366 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1425
Query: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWW
Sbjct: 1426 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1464
Query: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1465 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1524
Query: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1525 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1584
Query: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1585 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1644
Query: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1645 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1704
Query: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1705 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1764
Query: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1765 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1824
Query: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1825 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1884
Query: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1885 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1944
Query: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1945 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2004
Query: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2005 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2064
Query: 2101 FS 2102
FS
Sbjct: 2065 FS 2066
>gi|195976762 dysferlin isoform 13 [Homo sapiens]
Length = 2097
Score = 4168 bits (10809), Expect = 0.0
Identities = 2045/2133 (95%), Positives = 2050/2133 (96%), Gaps = 67/2133 (3%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 525
Query: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 526 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 585
Query: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 586 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 645
Query: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 646 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 705
Query: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 706 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765
Query: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 766 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825
Query: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 826 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885
Query: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 886 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 945
Query: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 946 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1005
Query: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1006 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1065
Query: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1066 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1125
Query: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1126 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1185
Query: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1186 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1245
Query: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1246 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1305
Query: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1306 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1365
Query: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1366 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1425
Query: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1426 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1485
Query: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529
IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1486 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1524
Query: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1525 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1584
Query: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1585 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1644
Query: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1645 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1704
Query: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1705 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1764
Query: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1765 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1824
Query: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1825 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1884
Query: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1885 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1944
Query: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1945 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2004
Query: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2005 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2064
Query: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2065 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
>gi|7305053 myoferlin isoform a [Homo sapiens]
Length = 2061
Score = 2381 bits (6171), Expect = 0.0
Identities = 1180/2126 (55%), Positives = 1520/2126 (71%), Gaps = 93/2126 (4%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ ASN+P K + DP+ S+ F+ KK+TK + N +NPVWNE E+DL+GIPL
Sbjct: 1 MLRVIVESASNIPKTKFGK-PDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLV 119
D S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++
Sbjct: 60 DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATID 119
Query: 120 LQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSG 179
L + Y P P P P L P++P + GEED D+ +
Sbjct: 120 LVIGYDP-----PSAPHPNDLS-GPSVPGMG----GDGEEDEGDEDRLDNAVR------- 162
Query: 180 GPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIK 239
GPG K P +R SR++LS+KPQDFQIRV+VIEGRQL G NI+
Sbjct: 163 GPGP-----KGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIR 217
Query: 240 PVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALL 299
PVVKV GQT RTRI +GN+P F+E F+N+ +P EL DE I I V +S SLR D L+
Sbjct: 218 PVVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLM 277
Query: 300 GEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPS 359
GEF++DVG +Y EP HA +RKWLLL+DP+D S+G++GY+K S+ VLG GDE P ER+D
Sbjct: 278 GEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRD 337
Query: 360 EDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDP 419
D +D+ESNLL P G+ALR F LK++RAED+PQMDDA VK+IFG ++KKNLVDP
Sbjct: 338 NDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDP 397
Query: 420 FVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATT 479
FVEVSFAGK +C+ I+EK ANP+WNQ + L FPS+CEK+++ I DWDRLT ND+V TT
Sbjct: 398 FVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTT 457
Query: 480 YLSMSKISAPGGEIEEEPAGAVKPSK--ASDLDDYLGFLPTFGPCYINLYGSPREFTGFP 537
YL +SKI+A GGE+E+ + + + + +GF+PTFGPCY+NLYGSPRE+TGFP
Sbjct: 458 YLHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFP 517
Query: 538 DPYTELNTGKGEGVAYRGRLLLSLETKLVE-HSEQKVEDLPADDILRVEKYLRRRKYSLF 596
DPY ELNTGKGEGVAYRGR+L+ L T L + ++K+E + DD+L VEKY RRRKYSL
Sbjct: 518 DPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLS 577
Query: 597 AAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNV 656
A F+SATMLQDV +AIQFEVSIGNYGNKFD TC PLASTTQYSRAVFDG +YYYLPW +
Sbjct: 578 AVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHT 637
Query: 657 KPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDE 716
KPVV L+SYWEDISHR++ N LL +A+RL+ +E + ++ + + L +L DE
Sbjct: 638 KPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDE 697
Query: 717 LIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDW 776
+I L + T LD + +LR+ LSQI EAA+ ++ +++ + L + EDW
Sbjct: 698 VIEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDW 757
Query: 777 LLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIF 836
L +L L EEPQNS+PDI+IWM++G+KR+AY R+PAHQVL+S G N GK CGK QTIF
Sbjct: 758 LDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIF 817
Query: 837 LKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWG 896
LKYP EK G ++PV++RV +W GLS EK+FN FAEG +VFAE YEN+ + G WG
Sbjct: 818 LKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQA--LMFGKWG 875
Query: 897 TTGLT-YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVF 955
T+GL KFSDVTGKIKL ++ F P GW W G+W V PE++LL + DAGH F +EV+
Sbjct: 876 TSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVY 935
Query: 956 ENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEY 1015
+N++R PGG W D YTD NG+K ++ CP GW+WED+ WS D+NRAVDE+GWEY
Sbjct: 936 QNESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEY 995
Query: 1016 SITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEG-EGWEYAS 1074
ITIPP+ KPK WV AEKMY+THRRRR VR R++DL+Q + E + EGWEYAS
Sbjct: 996 GITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYAS 1055
Query: 1075 LFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVM----DDKS-EDSM 1129
L GWKFH + R +D FRRRRWRR+M P E G AA+F LEGALG D+KS E
Sbjct: 1056 LIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQK 1115
Query: 1130 SVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKT 1189
+T FG N P +SC FD YHLRCY+YQAR+L A+DKDSFSDPYA + FLH+S+ T
Sbjct: 1116 HSATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTT 1175
Query: 1190 VVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQP- 1248
++ +TLNPTWDQT+IF E+EI+GEP TV + PP +++EL+D+D G DEF+GR I P
Sbjct: 1176 EIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPV 1235
Query: 1249 -----SLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1303
++ P+L W P+ G + G++L + ELI R K
Sbjct: 1236 VKLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGK--------------------- 1274
Query: 1304 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1363
+ ++LP PPQR N+YMVPQ I+P +Q TAIEILAWGLRNMK++Q+A+I+SPSLVVECG
Sbjct: 1275 DGSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECG 1334
Query: 1364 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1423
G+ V+S VI+NL+K PNF LFM+V LP+EELY PP+ +KVID+RQFGR+PVVGQCTI
Sbjct: 1335 GERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTI 1394
Query: 1424 RSLESFLCDPYSA-ESPSPQGGPDDVSLLS--PGEDVLIDIDDKEPLIPIQLADGLSSLA 1480
L+ F CDPY+ E PQ SLLS P D++I+++D +PL+ +L +
Sbjct: 1395 ERLDRFRCDPYAGKEDIVPQ---LKASLLSAPPCRDIVIEMEDTKPLLASKLTE------ 1445
Query: 1481 PTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGL 1540
EEE +DWWSKF+AS GE EKCG Y++K + LK+Y+ +LENV FEGL
Sbjct: 1446 -----------KEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGL 1494
Query: 1541 SDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQEC 1600
+DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L PQEC
Sbjct: 1495 TDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQEC 1553
Query: 1601 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1660
VRIYIVR LQP+D NG CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP
Sbjct: 1554 TVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLP 1613
Query: 1661 LEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRP 1720
EKDLKI++YDYD ++DEK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP
Sbjct: 1614 QEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRP 1673
Query: 1721 SQLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQ 1778
+QLL + P+ D R+ + ++YS++E EA +I + HLG EERLALH+L+
Sbjct: 1674 TQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILR 1733
Query: 1779 QQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCI 1838
QGLVPEHVE+R L+S QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR I
Sbjct: 1734 TQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVI 1793
Query: 1839 IWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFD 1898
IWNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFD
Sbjct: 1794 IWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFD 1853
Query: 1899 YLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPA 1958
YLPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+LG L+LDL PA
Sbjct: 1854 YLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPA 1913
Query: 1959 KTAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2014
K+ +KC LD + D A +P SLFEQK++KGWWPC AE+ +++AGK+EMTLEI+
Sbjct: 1914 KSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEIL 1973
Query: 2015 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2074
E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II +
Sbjct: 1974 NEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLF 2033
Query: 2075 LFILLLFLAIFIYAFPNYAAMKLVKP 2100
L ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2034 LLILLLFVAVLLYSLPNYLSMKIVKP 2059
>gi|19718759 myoferlin isoform b [Homo sapiens]
Length = 2048
Score = 2379 bits (6166), Expect = 0.0
Identities = 1180/2124 (55%), Positives = 1516/2124 (71%), Gaps = 102/2124 (4%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ ASN+P K + DP+ S+ F+ KK+TK + N +NPVWNE E+DL+GIPL
Sbjct: 1 MLRVIVESASNIPKTKFGK-PDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLV 119
D S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++
Sbjct: 60 DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATID 119
Query: 120 LQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSG 179
L + Y P P P P L P++P + GEED D+ +
Sbjct: 120 LVIGYDP-----PSAPHPNDLS-GPSVPGMG----GDGEEDEGDEDRLDNAVR------- 162
Query: 180 GPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIK 239
GPG K P +R SR++LS+KPQDFQIRV+VIEGRQL G NI+
Sbjct: 163 GPGP-----KGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIR 217
Query: 240 PVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALL 299
PVVKV GQT RTRI +GN+P F+E F+N+ +P EL DE I I V +S SLR D L+
Sbjct: 218 PVVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLM 277
Query: 300 GEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPS 359
GEF++DVG +Y EP HA +RKWLLL+DP+D S+G++GY+K S+ VLG GDE P ER+D
Sbjct: 278 GEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRD 337
Query: 360 EDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDP 419
D +D+ESNLL P G+ALR F LK++RAED+PQMDDA VK+IFG ++KKNLVDP
Sbjct: 338 NDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDP 397
Query: 420 FVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATT 479
FVEVSFAGK +C+ I+EK ANP+WNQ + L FPS+CEK+++ I DWDRLT ND+V TT
Sbjct: 398 FVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTT 457
Query: 480 YLSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDP 539
YL +SKI+A GGE+E + +GF+PTFGPCY+NLYGSPRE+TGFPDP
Sbjct: 458 YLHLSKIAASGGEVEVNTG-----------ETEVGFVPTFGPCYLNLYGSPREYTGFPDP 506
Query: 540 YTELNTGKGEGVAYRGRLLLSLETKLVE-HSEQKVEDLPADDILRVEKYLRRRKYSLFAA 598
Y ELNTGKGEGVAYRGR+L+ L T L + ++K+E + DD+L VEKY RRRKYSL A
Sbjct: 507 YDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAV 566
Query: 599 FYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKP 658
F+SATMLQDV +AIQFEVSIGNYGNKFD TC PLASTTQYSRAVFDG +YYYLPW + KP
Sbjct: 567 FHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKP 626
Query: 659 VVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELI 718
VV L+SYWEDISHR++ N LL +A+RL+ +E + ++ + + L +L DE+I
Sbjct: 627 VVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVI 686
Query: 719 AGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLL 778
L + T LD + +LR+ LSQI EAA+ ++ +++ + L + EDWL
Sbjct: 687 EDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLD 746
Query: 779 RLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLK 838
+L L EEPQNS+PDI+IWM++G+KR+AY R+PAHQVL+S G N GK CGK QTIFLK
Sbjct: 747 KLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLK 806
Query: 839 YPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTT 898
YP EK G ++PV++RV +W GLS EK+FN FAEG +VFAE YEN+ + G WGT+
Sbjct: 807 YPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQA--LMFGKWGTS 864
Query: 899 GLT-YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFEN 957
GL KFSDVTGKIKL ++ F P GW W G+W V PE++LL + DAGH F +EV++N
Sbjct: 865 GLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQN 924
Query: 958 QTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSI 1017
++R PGG W D YTD NG+K ++ CP GW+WED+ WS D+NRAVDE+GWEY I
Sbjct: 925 ESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGI 984
Query: 1018 TIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEG-EGWEYASLF 1076
TIPP+ KPK WV AEKMY+THRRRR VR R++DL+Q + E + EGWEYASL
Sbjct: 985 TIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASLI 1044
Query: 1077 GWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVM----DDKS-EDSMSV 1131
GWKFH + R +D FRRRRWRR+M P E G AA+F LEGALG D+KS E
Sbjct: 1045 GWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHS 1104
Query: 1132 STLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVV 1191
+T FG N P +SC FD YHLRCY+YQAR+L A+DKDSFSDPYA + FLH+S+ T +
Sbjct: 1105 ATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEI 1164
Query: 1192 VKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQP--- 1248
+ +TLNPTWDQT+IF E+EI+GEP TV + PP +++EL+D+D G DEF+GR I P
Sbjct: 1165 IHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVK 1224
Query: 1249 ---SLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESED 1305
++ P+L W P+ G + G++L + ELI R K +
Sbjct: 1225 LNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGK---------------------DG 1263
Query: 1306 TDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQ 1365
++LP PPQR N+YMVPQ I+P +Q TAIEILAWGLRNMK++Q+A+I+SPSLVVECGG+
Sbjct: 1264 SNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGGE 1323
Query: 1366 TVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRS 1425
V+S VI+NL+K PNF LFM+V LP+EELY PP+ +KVID+RQFGR+PVVGQCTI
Sbjct: 1324 RVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIER 1383
Query: 1426 LESFLCDPYSA-ESPSPQGGPDDVSLLS--PGEDVLIDIDDKEPLIPIQLADGLSSLAPT 1482
L+ F CDPY+ E PQ SLLS P D++I+++D +PL+ +L +
Sbjct: 1384 LDRFRCDPYAGKEDIVPQ---LKASLLSAPPCRDIVIEMEDTKPLLASKLTE-------- 1432
Query: 1483 NTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSD 1542
EEE +DWWSKF+AS GE EKCG Y++K + LK+Y+ +LENV FEGL+D
Sbjct: 1433 ---------KEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTD 1483
Query: 1543 FCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLV 1602
F +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L PQEC V
Sbjct: 1484 FSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTV 1542
Query: 1603 RIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLE 1662
RIYIVR LQP+D NG CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP E
Sbjct: 1543 RIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQE 1602
Query: 1663 KDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQ 1722
KDLKI++YDYD ++DEK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP+Q
Sbjct: 1603 KDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQ 1662
Query: 1723 LLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQ 1780
LL + P+ D R+ + ++YS++E EA +I + HLG EERLALH+L+ Q
Sbjct: 1663 LLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQ 1722
Query: 1781 GLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIW 1840
GLVPEHVE+R L+S QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR IIW
Sbjct: 1723 GLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIW 1782
Query: 1841 NTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYL 1900
NT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFDYL
Sbjct: 1783 NTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYL 1842
Query: 1901 PAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKT 1960
PAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+LG L+LDL PAK+
Sbjct: 1843 PAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKS 1902
Query: 1961 AKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAE 2016
+KC LD + D A +P SLFEQK++KGWWPC AE+ +++AGK+EMTLEI+ E
Sbjct: 1903 PEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNE 1962
Query: 2017 SEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILF 2076
E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II + L
Sbjct: 1963 KEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLL 2022
Query: 2077 ILLLFLAIFIYAFPNYAAMKLVKP 2100
ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2023 ILLLFVAVLLYSLPNYLSMKIVKP 2046
>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
Length = 2093
Score = 1438 bits (3723), Expect = 0.0
Identities = 858/2178 (39%), Positives = 1216/2178 (55%), Gaps = 269/2178 (12%)
Query: 23 PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82
P S+ FR +KKRT+V++ + +PVWNE W L PL+ S L V ++D + + RF+
Sbjct: 21 PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
Query: 83 GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPLE 141
G A V L+ +L PS + + LL+ +PT ++ LQV++
Sbjct: 80 GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH----------------- 122
Query: 142 PSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGI 201
+ + D+ TG E+ G+T EA +KL PG
Sbjct: 123 ----MSNQDI-EKTGAEDHL---GITAREA--------------ASQKLM------VPG- 153
Query: 202 KRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSP 261
T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ +TRI GN+P
Sbjct: 154 ------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNP 207
Query: 262 LFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKW 321
FNE F N + P + FDE I I + D+G IY P H LRKW
Sbjct: 208 FFNEIFFQNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKW 250
Query: 322 LLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAH 381
L L P++ +G GYLK ++ LG GD+A +++K +D + + + V + A+
Sbjct: 251 LGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAY 309
Query: 382 FCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANP 441
L ++ AEDL K V+P +EV G+ L + + +T NP
Sbjct: 310 LQLFIYCAEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNP 352
Query: 442 QWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAV 501
WNQ +T P + ++ R++D + D + T LS+++IS+ G EIE + + +
Sbjct: 353 IWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQS--L 410
Query: 502 KPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSL 561
+P+ + Y GFLP FGP ++ L+G + + + +G+AYRGR+ L L
Sbjct: 411 EPTSYTPRV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLEL 469
Query: 562 ETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNY 621
T++ + + ++DL + ++ R+EK+ R+KY L F S TM+ + + I FEVSIG+Y
Sbjct: 470 ITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHY 528
Query: 622 GNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLG 681
GNK D+ PL S+T YS ++DG Y+Y+PW N KPVV ++S WED+S R+ N L
Sbjct: 529 GNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHF 588
Query: 682 IADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQ 739
DRL+A L+ LK+ + +D L +L EL C +PL + P AT LD+
Sbjct: 589 TRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDR 644
Query: 740 YLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWML 799
+QLR+ L + LA K ++ + AEDWL RL + EPQ LPD++IW++
Sbjct: 645 KRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLV 699
Query: 800 QGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWF 859
++RVAY +VPAH VLFS GA + G+ CGK+QT+FL+YP + +P +RV +W
Sbjct: 700 AKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWL 759
Query: 860 GLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDS 918
G D K+ +G +V+AE YEN+ K WG GL + P FSDV G LP
Sbjct: 760 GNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTD 817
Query: 919 FRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNG 978
F+P GW W W V P++ LL D+D +EEV+ENQ R G W + TDVNG
Sbjct: 818 FQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNG 877
Query: 979 EKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTH 1038
+ + +++++CP GW ++ ++W +LN AVD WEY + IPP P+ W P EK Y++
Sbjct: 878 QPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSC 934
Query: 1039 RRRRWVRLRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTD 1088
RRRRW R+R R+ ++ H Q A+ E EGWEY + FG KFHL +
Sbjct: 935 RRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQS 989
Query: 1089 AFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD--------------------- 1123
FRRR WRRR+ P + G A +F LEG+L G V ++
Sbjct: 990 RFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLS 1049
Query: 1124 ------------KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLR 1156
K EDS T +G++R P I C F+ + Y L
Sbjct: 1050 WVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLF 1106
Query: 1157 CYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPA 1216
CY+YQAR+L + +F P+ V FL+ SQ T ++++ PTW QTLIF + ++ P
Sbjct: 1107 CYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQ 1166
Query: 1217 TVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSG 1269
E PP +V+EL+ D +G + GR + P + +P + W PL + + G
Sbjct: 1167 DTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEG 1226
Query: 1270 ELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKP 1328
E+LAS ELI Q EK +P V P+ + Y +P++I+P
Sbjct: 1227 EILASCELILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQP 1266
Query: 1329 ALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTL 1386
++R AIEILAWGLRNMK SSP L+VE G +++++ IR+ + NPNF L
Sbjct: 1267 TIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVL 1321
Query: 1387 FMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPD 1446
+ V++P EE Y P+ VKV+DN FG++ V GQ I L+ + CDP++ + P+
Sbjct: 1322 VLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---- 1377
Query: 1447 DVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEF---IDWWSKF 1503
L + +K+ D L L SS E+E+ +DWWSK
Sbjct: 1378 -----------LPTLSEKKH------QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKL 1418
Query: 1504 FASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSV 1563
F + E + Y KD+ TLKVY+ +LE V AF+GL DFC TFKLY+ ++ D V
Sbjct: 1419 FWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPV 1474
Query: 1564 IGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKC 1621
+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+Y+VRA LQP+D NG C
Sbjct: 1475 VGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLC 1534
Query: 1622 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1681
DPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KI
Sbjct: 1535 DPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKI 1594
Query: 1682 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--R 1739
G TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL + ++ + P++
Sbjct: 1595 GTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE 1654
Query: 1740 TDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQP 1798
D V + K++ ++ E + P H LGP +ERLAL++L QGLVPEHVE+R LYS QP
Sbjct: 1655 EDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQP 1713
Query: 1799 DIEQGKLQMWVDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVILDD 1849
I+QGK+QMWVD+FPK LG PGP NI PR+ + R+ LRCIIW T +V L D
Sbjct: 1714 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVD 1773
Query: 1850 LSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIA 1909
+L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL AE+ C +
Sbjct: 1774 DNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQS 1833
Query: 1910 KKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQL 1969
+KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+ +
Sbjct: 1834 QKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMM 1893
Query: 1970 DDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEER 2022
D P+W SLF++KTV GWWPC +G K L+GK++M+LEI++E E +
Sbjct: 1894 D--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIK 1951
Query: 2023 PAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFL 2082
PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F+++ I+ L L
Sbjct: 1952 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 2011
Query: 2083 AIFIYAFPNYAAMKLVKP 2100
FIY+ P+Y AM +KP
Sbjct: 2012 FNFIYSAPHYLAMSWIKP 2029
Score = 40.0 bits (92), Expect = 0.024
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 239 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 298
+P + + KRTR+ +GN P++NETL ++L++ P E D + +T+ D S + +
Sbjct: 20 RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
Query: 299 LGEFRMDVGTIYREPRHAYLRKWLLL 324
+G + + + ++P K L L
Sbjct: 79 IGLATVLLKPLLKQPSEVLFVKDLTL 104
>gi|35493868 otoferlin isoform b [Homo sapiens]
Length = 1230
Score = 726 bits (1875), Expect = 0.0
Identities = 409/1057 (38%), Positives = 590/1057 (55%), Gaps = 128/1057 (12%)
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1253
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320
Query: 1254 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1310
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360
Query: 1311 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1367
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420
Query: 1368 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1427
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480
Query: 1428 SFLCDPYSAESPSPQGGPDDVSLLSPGEDV-----LIDID-DKEPLIPIQLADGLSSLAP 1481
F+ P +PS + V + P + ++ +D E ++ + +A+
Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540
Query: 1482 TNTAS---PPSSPHEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1520
+ P +E +DWWSK+FASI ++E G LE+
Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600
Query: 1521 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1543
D LKVY +LE+ F+ D+
Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658
Query: 1544 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1593
+TF L RGKT ++ TE+ ++G FKG +Y PLPED + F +
Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718
Query: 1594 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1653
+ P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F
Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778
Query: 1654 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1713
++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N
Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838
Query: 1714 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1771
WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E
Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895
Query: 1772 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1823
+AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P
Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955
Query: 1824 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1882
+I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015
Query: 1883 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1942
L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075
Query: 1943 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 2001
FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134
Query: 2002 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2061
L GK+E L ++ E E+ P G R+EP+ LE P RPDTSF+WF +P K+ ++ L
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFL 1191
Query: 2062 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2098
W +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1192 WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1228
Score = 87.4 bits (215), Expect = 1e-16
Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)
Query: 715 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 769
+EL GC + L D + S+ T LD+ + L + + A L+ + +
Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77
Query: 770 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 829
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136
Query: 830 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 868
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 409 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262
>gi|35493853 otoferlin isoform c [Homo sapiens]
Length = 1307
Score = 723 bits (1867), Expect = 0.0
Identities = 418/1084 (38%), Positives = 593/1084 (54%), Gaps = 162/1084 (14%)
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 258 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 317
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1253
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 318 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 377
Query: 1254 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1310
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 378 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 417
Query: 1311 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1367
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 418 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 477
Query: 1368 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1427
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 478 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 537
Query: 1428 SFLCDPYSAESPS--------------PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLA 1473
F+ P +PS GG S S GE V+ EP +PI+
Sbjct: 538 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGS---SSHSTGEVVVT----MEPEVPIKKL 590
Query: 1474 DGLSSLAPTNTA----------------------SPPSSPHEEEFIDWWSKFFASIG--- 1508
+ + L T+ A P +E +DWWSK+FASI
Sbjct: 591 ETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMK 650
Query: 1509 ----EREKCGSYLEKD-------------------------------------------- 1520
++E G LE+
Sbjct: 651 EQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEK 710
Query: 1521 ----FDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFK 1572
D LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG
Sbjct: 711 KKPKIDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC 768
Query: 1573 IY--PLPEDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIK 1626
+Y PLPED + F + + P LVR+Y+VRA L P D NGK DPYI
Sbjct: 769 VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIA 828
Query: 1627 ISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVV 1686
I +GK + D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET +
Sbjct: 829 IRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKI 888
Query: 1687 DLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMF 1745
DLENR SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV
Sbjct: 889 DLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKV 948
Query: 1746 QDKEYS-IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPL 1796
++ ++ EIE N P +E +AL L+ LVPEHVE+RPL +P
Sbjct: 949 ANRVFTGPSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPD 1005
Query: 1797 QPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGE 1855
+P IEQG+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGE
Sbjct: 1006 KPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGE 1065
Query: 1856 KMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFW 1915
K SDI+V+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ +
Sbjct: 1066 KSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMF 1125
Query: 1916 RLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHP 1975
D+TE KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++
Sbjct: 1126 SWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDV 1185
Query: 1976 EWFVSLFEQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMN 2034
VS+F+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+
Sbjct: 1186 P-LVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD-- 1242
Query: 2035 PKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAA 2094
LE P RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y
Sbjct: 1243 -PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLV 1301
Query: 2095 MKLV 2098
K++
Sbjct: 1302 KKIL 1305
Score = 91.3 bits (225), Expect = 9e-18
Identities = 71/211 (33%), Positives = 110/211 (52%), Gaps = 21/211 (9%)
Query: 666 WEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ-- 723
W I+H ++Q E GL + +K + S + + + +EL GC +
Sbjct: 38 WPSITHTPDSQ----------EEGLNDIQEMIKTEKSYPE--RRLRGVLEELSCGCCRFL 85
Query: 724 PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAALEQAEDWLLRL 780
L D + S+ T LD+ + L + + A L+ + + L +++L +L
Sbjct: 86 SLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKL 145
Query: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
R LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C K++T+FLK P
Sbjct: 146 RFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLP 204
Query: 841 MEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 868
++ G A VQ +V+ LW GLS KEF
Sbjct: 205 GKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 235
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 409 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 283 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 319
>gi|34740331 otoferlin isoform a [Homo sapiens]
Length = 1997
Score = 723 bits (1867), Expect = 0.0
Identities = 418/1084 (38%), Positives = 593/1084 (54%), Gaps = 162/1084 (14%)
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 948 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 1007
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1253
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 1008 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 1067
Query: 1254 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1310
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 1068 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 1107
Query: 1311 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1367
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 1108 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 1167
Query: 1368 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1427
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 1168 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 1227
Query: 1428 SFLCDPYSAESPS--------------PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLA 1473
F+ P +PS GG S S GE V+ EP +PI+
Sbjct: 1228 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGS---SSHSTGEVVVT----MEPEVPIKKL 1280
Query: 1474 DGLSSLAPTNTA----------------------SPPSSPHEEEFIDWWSKFFASIG--- 1508
+ + L T+ A P +E +DWWSK+FASI
Sbjct: 1281 ETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMK 1340
Query: 1509 ----EREKCGSYLEKD-------------------------------------------- 1520
++E G LE+
Sbjct: 1341 EQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEK 1400
Query: 1521 ----FDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFK 1572
D LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG
Sbjct: 1401 KKPKIDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC 1458
Query: 1573 IY--PLPEDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIK 1626
+Y PLPED + F + + P LVR+Y+VRA L P D NGK DPYI
Sbjct: 1459 VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIA 1518
Query: 1627 ISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVV 1686
I +GK + D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET +
Sbjct: 1519 IRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKI 1578
Query: 1687 DLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMF 1745
DLENR SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV
Sbjct: 1579 DLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKV 1638
Query: 1746 QDKEYS-IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPL 1796
++ ++ EIE N P +E +AL L+ LVPEHVE+RPL +P
Sbjct: 1639 ANRVFTGPSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPD 1695
Query: 1797 QPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGE 1855
+P IEQG+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGE
Sbjct: 1696 KPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGE 1755
Query: 1856 KMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFW 1915
K SDI+V+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ +
Sbjct: 1756 KSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMF 1815
Query: 1916 RLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHP 1975
D+TE KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++
Sbjct: 1816 SWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDV 1875
Query: 1976 EWFVSLFEQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMN 2034
VS+F+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+
Sbjct: 1876 P-LVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD-- 1932
Query: 2035 PKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAA 2094
LE P RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y
Sbjct: 1933 -PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLV 1991
Query: 2095 MKLV 2098
K++
Sbjct: 1992 KKIL 1995
Score = 391 bits (1004), Expect = e-108
Identities = 293/945 (31%), Positives = 464/945 (49%), Gaps = 131/945 (13%)
Query: 20 RSDPVASLTFRGVKKRTKVIKNSVNPV-WNEGFEWDLKGIPLDQGSELHVVVKDHETMGR 78
R D +A +TFRG ++V++N + ++E F W + +D+ L + V ++ +
Sbjct: 16 RGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVAS-SIDRNEMLEIQVFNYSKVFS 74
Query: 79 NRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPT 138
N+ +G ++ L++V+ + + L+D SL ++V Y G V +
Sbjct: 75 NKLIGTFRMVLQKVVEESHVEVTDT--LIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGD 132
Query: 139 PL-------------EPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPF---LDQSGGPG 182
L E LP + GE+ G + A P
Sbjct: 133 FLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQ 192
Query: 183 APTTPRKLPSRPPPHYP----------------------GIKRKRSAPTSRKLLS-DKPQ 219
P P L H + KRS P + S +P
Sbjct: 193 RPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPM 252
Query: 220 DFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSPGEL 278
D+Q+ + VIE RQL G+N+ PVV V K T + + N P +NE F+ SP +
Sbjct: 253 DYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVM 312
Query: 279 FDEPIFITVVDSRSL-RTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGY 337
FD+ I I+V+ S++L R+ L+G F+MDVGT+Y +P H + KW +LSDPDD S+G +GY
Sbjct: 313 FDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGY 372
Query: 338 LKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGV--ALRGAHFCLKVFRAEDLPQM 395
+K + V+G GD K D++DIE NLL P GV + A F +K++RAE LP+M
Sbjct: 373 VKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRM 432
Query: 396 DDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPS 455
+ ++M NVK+ F E+ K+LVDP+V+V FAG+ + + + + P WN+ + +FP
Sbjct: 433 NTSLMANVKKAFIGEN--KDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPP 490
Query: 456 MCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLG 514
+C++M+++I D D++ ND+ + T ++ + KIS G + G
Sbjct: 491 LCKRMKVQIRDSDKV--NDVAIGTHFIDLRKISNDGDK---------------------G 527
Query: 515 FLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVE 574
FLPT GP ++N+YGS R +T D + +LN G GEGV++R RLLL L ++V+ S
Sbjct: 528 FLPTLGPAWVNMYGSTRNYT-LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSN---P 583
Query: 575 DLPADDILRVEKYL--------RRRKYSLFAAFYSATML--QDVDDAIQFEVSIGNYGNK 624
+L + ++VE+ + ++ LF AF A+M+ ++ D I FEV+IGNYGN+
Sbjct: 584 ELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNE 643
Query: 625 FDMTCLP---------------------------------LASTTQYSRAVFDGCHYYYL 651
D P S+T R +Y++L
Sbjct: 644 VDGLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHL 703
Query: 652 PWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVA 711
P+ KP + + S+W D R+ N + IAD+LE GL + +K + S + +
Sbjct: 704 PYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYP--ERRLR 761
Query: 712 QLTDELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAA--LALKLGHSEL 766
+ +EL GC + L D + S+ T LD+ + L + + A L ++ +
Sbjct: 762 GVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTV 821
Query: 767 PAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCG 826
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS G
Sbjct: 822 RDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETG 880
Query: 827 KNCGKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 868
K+C K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 881 KDCAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 925
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 409 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 973 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 1009
Score = 32.3 bits (72), Expect = 5.0
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 1175 DPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1209
DPY V F Q KT V K++ P W++ ++F ++
Sbjct: 453 DPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDL 487
>gi|119120884 fer-1-like 6 [Homo sapiens]
Length = 1857
Score = 720 bits (1858), Expect = 0.0
Identities = 406/1082 (37%), Positives = 585/1082 (54%), Gaps = 145/1082 (13%)
Query: 1131 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1190
+S+ G N P + ++ + + LR +MYQAR L A D + SDP+A V+FL Q T
Sbjct: 804 MSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTK 863
Query: 1191 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL 1250
++ TL+PTW+Q L+F ++ + G+ +AE PP +VVELYD D G E++G + P +
Sbjct: 864 IISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVV 923
Query: 1251 E------RMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1304
+ PRL + P+ G+ G+LLA FEL+Q + +P
Sbjct: 924 KLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLP--------------- 968
Query: 1305 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1364
P PP IY VP NI+P L + +E+L WG+R MK QL ++ P ++ECGG
Sbjct: 969 ----PVEPPDI-TQIYPVPANIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQALIECGG 1023
Query: 1365 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1424
Q V+SCVI++ + NPNF I EV LP EL PP+++ V+D R FGR +VG TI
Sbjct: 1024 QGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTIN 1083
Query: 1425 SLESFLCDPYSAESPSPQ-------------------GGPDDVSLLSPGEDVLIDID--- 1462
L+ FLC +P Q G S P + + +D++
Sbjct: 1084 YLKQFLCKLREPLAPITQVDGTQPGHDISDSLTATESSGAHSSSQDPPADHIYVDVEPPP 1143
Query: 1463 -------DKEPLIPIQLADGLSSLAPTNTASPPSSPHE---------------------- 1493
+P I + + D L P +T P +
Sbjct: 1144 TVVPDSAQAQPAILVDVPDSSPMLEPEHTPVAQEPPKDGKPKDPRKPSRRSTKRRKRTIA 1203
Query: 1494 ----EEFIDWWSKFFASI-------------------------------GEREKCGSYLE 1518
E IDWWSK++AS+ G ++K L+
Sbjct: 1204 DESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKKDKMLK 1263
Query: 1519 K--------DFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEET---EDPSVIGEF 1567
K + L++YD LE+ F D+ TF+L+RGK+ E+ + VIG+F
Sbjct: 1264 KKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDRVIGKF 1321
Query: 1568 KGLFKIYPLPEDPAIPMPPRQFHQ--LAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI 1625
KG F IY P+D + + Q + P L+R+YIV AF L P DP+GK DPYI
Sbjct: 1322 KGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSDPYI 1381
Query: 1626 KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV 1685
I +GK + D+D YIP L PVFG+ FE+ T P E L I +YD+D++ D+ IGET
Sbjct: 1382 VIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIGETK 1441
Query: 1686 VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF 1745
+DLENR SK A CGL Y + G N WRD +P+++L C+ +++ P + ++
Sbjct: 1442 IDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHPGKIQI 1501
Query: 1746 QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQ 1797
++ +S + I + + E LAL VL LVPEH+E+RPLY +
Sbjct: 1502 GNQVFSGKTIFTEEDTDETVESYEH-LALKVLHSWEDIPEVGCRLVPEHIETRPLYHKDK 1560
Query: 1798 PDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSL-TGEK 1856
P +EQG+LQMWVD+FPK + +PGPP +I+PRR + + LR IWNT DVIL+D ++ TG+K
Sbjct: 1561 PGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFTGQK 1620
Query: 1857 MSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWR 1916
SDIYVKGW+ G E+ KQ+TDVHY SL GEGNFNWRF+FPF YLPAE+ I K++ +
Sbjct: 1621 SSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKRENIFS 1680
Query: 1917 LDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPE 1976
L+K E K PA +V Q+WD ++ S DDFLG+L+++LN P+ AK+AK C L + ++A E
Sbjct: 1681 LEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENA-SEE 1739
Query: 1977 WFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPK 2036
+S+F+QK V+GWWP + K L GK+E +V E E+ P G+ R EP
Sbjct: 1740 TKISIFQQKRVRGWWPF----SKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPE---P 1792
Query: 2037 LEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMK 2096
L P RPDTSF WF SP+K + +++W+ ++ II+ IL IL++FL +FIY P + +
Sbjct: 1793 LAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAISRR 1852
Query: 2097 LV 2098
+V
Sbjct: 1853 IV 1854
Score = 343 bits (879), Expect = 1e-93
Identities = 235/738 (31%), Positives = 373/738 (50%), Gaps = 126/738 (17%)
Query: 217 KPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSP 275
+ Q++QI + + E RQL G NI PVV + + K++ + +G NSP +NE F+
Sbjct: 79 RSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQ 138
Query: 276 GELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGAR 335
LFD+ I I+V + + + L+G F++D+GT+Y +P H + KW LL+DP D G +
Sbjct: 139 VHLFDKIIKISVFHHKLIGS-VLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTK 197
Query: 336 GYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALR--GAHFCLKVFRAEDLP 393
GYLK + V+G GD K S+ +E IE NLL P G L A F +++++AE LP
Sbjct: 198 GYLKCDISVMGKGDVLKTSPK-TSDTEEPIEKNLLIPNGFPLERPWARFYVRLYKAEGLP 256
Query: 394 QMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMF 453
+M+ ++M NV + F + K+LVDPFVEVSFAG+M + + + A+P W++ + MF
Sbjct: 257 KMNSSIMANVTK--AFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMF 314
Query: 454 PSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLDDY 512
P +C +++I++ WD + ND+ +AT ++ + KIS ++ D
Sbjct: 315 PPLCRRVKIQV--WDEGSMNDVALATHFIDLKKIS-------------------NEQDGD 353
Query: 513 LGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ- 571
GFLPTFGP +INLYGSPR + D Y E+N G GEGV++RGR+L+ + +++ Q
Sbjct: 354 KGFLPTFGPAWINLYGSPRNHS-LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQE 412
Query: 572 -------KVEDLPADD------------------------------ILRVEKY------- 587
K LP+ D + VE +
Sbjct: 413 SKFSKALKELKLPSKDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIV 472
Query: 588 -LRRRKYSLFAAFYSATMLQDV--DDAIQFEVSIGNYGNKFD------------------ 626
+ ++ LF AF+ ATM+ D I FEVSIGN+GN D
Sbjct: 473 PEKNEEFLLFGAFFEATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDL 532
Query: 627 -------------MTCLPLASTTQYSRAVF--DGCHYYYLPWGNVKPVVVLSSYWEDISH 671
+P+ASTT + + +Y YLP+ KP V S W D +
Sbjct: 533 LPLLHEGQGDVAHDVPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTF 592
Query: 672 RIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHET 731
R+ N L +AD LE +E+V +K S E + + + + I+ S + + +
Sbjct: 593 RLHWSNMLEKMADFLEESIEEVRELIK--ISQEAPEEKMKTVLSDFISRSSAFISEAEKK 650
Query: 732 P---SATHLDQYLYQLRTHHLSQITEAALAL------KLGHSELPAALEQAEDWLLRLRA 782
P + T LD+ L L + + A + KL E+ + +A++++ ++R
Sbjct: 651 PKMLNQTTLDKKRLTLCWQELEAMCKEAKGIIQQQKKKLSVDEM---IHEAQNFVEKIRF 707
Query: 783 LAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPME 842
L +EPQ+++PD+ IWML ++RVAY R+ + +L+S A GK+CGK++T FLK P +
Sbjct: 708 LVDEPQHTIPDVFIWMLSNNRRVAYARIASKDLLYS-PVAGQMGKHCGKIKTHFLKPPGK 766
Query: 843 KVPGARMPVQIRVKLWFG 860
+ G + ++ V LW G
Sbjct: 767 RPAGWSVQAKVDVYLWLG 784
Score = 45.4 bits (106), Expect = 6e-04
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 6 LVRASNLPSAKKDRRSDP--VASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQG 63
+V A NL A D +SDP V L +K R K I +NPV+ FE +
Sbjct: 1362 IVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQAT---FPKE 1418
Query: 64 SELHVVVKDHETMGRNRFLGEAKVPL 89
S L +++ DH+ +G + +GE K+ L
Sbjct: 1419 SLLSILIYDHDMIGTDDLIGETKIDL 1444
Score = 35.8 bits (81), Expect = 0.45
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 1169 DKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1209
D DP+ VSF Q +T V KN +P W + +IF E+
Sbjct: 273 DSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEM 313
Score = 35.4 bits (80), Expect = 0.59
Identities = 51/209 (24%), Positives = 80/209 (38%), Gaps = 47/209 (22%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNE-------GFEWDLKGI 58
+ +A L +A + SDP A +TF + TK+I +++P WN+ D+K
Sbjct: 832 MYQARGLIAADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNDLVLHGDVK-- 889
Query: 59 PLDQGSELHVV-VKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQP---- 113
L + L VV + D + +G+ +LG +A P + L D +P
Sbjct: 890 ELAESPPLVVVELYDSDAVGKPEYLG-------ATVAAPVVK------LADQDYEPPRLC 936
Query: 114 ---------TGASL-----VLQVSYTPLPGAVPLFPP------PTPLEPSPTLPDLDVVA 153
+G L +LQV + L G P+ PP P P P L V
Sbjct: 937 YHPIFCGNLSGGDLLAVFELLQVPPSGLQGLPPVEPPDITQIYPVPANIRPVLSKYRVEV 996
Query: 154 DTGGEEDTEDQGLTGDEAEPFLDQSGGPG 182
G + + L + L + GG G
Sbjct: 997 LFWGVREMKKVQLLSVDRPQALIECGGQG 1025
Score = 33.5 bits (75), Expect = 2.3
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 411 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445
++ L DPF +V+F +KI+ +T +P WNQ
Sbjct: 841 ADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQ 875
>gi|35493860 otoferlin isoform d [Homo sapiens]
Length = 1230
Score = 719 bits (1856), Expect = 0.0
Identities = 407/1057 (38%), Positives = 589/1057 (55%), Gaps = 128/1057 (12%)
Query: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260
Query: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1253
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320
Query: 1254 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1310
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360
Query: 1311 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1367
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420
Query: 1368 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1427
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480
Query: 1428 SFLCDPYSAESPSPQGGPDDVSLLSPGEDV-----LIDID-DKEPLIPIQLADGLSSLAP 1481
F+ P +PS + V + P + ++ +D E ++ + +A+
Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540
Query: 1482 TNTAS---PPSSPHEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1520
+ P +E +DWWSK+FASI ++E G LE+
Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600
Query: 1521 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1543
D LKVY +LE+ F+ D+
Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658
Query: 1544 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1593
+TF L RGKT ++ TE+ ++G FKG +Y PLPED + F +
Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718
Query: 1594 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1653
+ P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F
Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778
Query: 1654 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1713
++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N
Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838
Query: 1714 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1771
WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E
Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895
Query: 1772 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1823
+AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P
Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955
Query: 1824 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1882
+I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015
Query: 1883 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1942
L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075
Query: 1943 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 2001
FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134
Query: 2002 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2061
L GK+E L ++ E E+ P G R+EP+ LE P RPDT+F+WF +P K++K+++
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTAFVWFLNPLKSIKYLI 1191
Query: 2062 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2098
R++W II ++ + LL L +F+Y+ P Y KL+
Sbjct: 1192 CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVKKLL 1228
Score = 87.4 bits (215), Expect = 1e-16
Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)
Query: 715 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 769
+EL GC + L D + S+ T LD+ + L + + A L+ + +
Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77
Query: 770 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 829
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136
Query: 830 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 868
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 409 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262
>gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
Length = 802
Score = 711 bits (1836), Expect = 0.0
Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%)
Query: 1354 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1411
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
Query: 1412 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1471
FG++ V GQ I L+ + CDP++ + P+ L + +K+
Sbjct: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104
Query: 1472 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1528
D L L SS E+E+ +DWWSK F + E + Y KD+ TLKVY+
Sbjct: 105 -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160
Query: 1529 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1588
+LE V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP Q
Sbjct: 161 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217
Query: 1589 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1646
F + PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+
Sbjct: 218 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277
Query: 1647 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1706
P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 278 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337
Query: 1707 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1764
C SGP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H
Sbjct: 338 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396
Query: 1765 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1823
LGP +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP
Sbjct: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456
Query: 1824 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1883
NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL
Sbjct: 457 NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516
Query: 1884 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1943
GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND FS DDF
Sbjct: 517 TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576
Query: 1944 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 1996
LG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GWWPC
Sbjct: 577 LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634
Query: 1997 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2056
+G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W SP +
Sbjct: 635 DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694
Query: 2057 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
+I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 695 FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738
>gi|4759026 RAS protein activator like 1 [Homo sapiens]
Length = 804
Score = 65.5 bits (158), Expect = 5e-10
Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 13/127 (10%)
Query: 1155 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1214
LRC++ ARDLA D SDP+A V + QS +T +K T P WD+ L E
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVL---------E 185
Query: 1215 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-SLERMPRLAWF---PLTRGSQPSGE 1270
+ P + VEL+D D G ++F+G P +L++ P WF P R + SG
Sbjct: 186 LREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAEEDSGG 245
Query: 1271 LLASFEL 1277
L + +
Sbjct: 246 NLGALRV 252
Score = 45.1 bits (105), Expect = 7e-04
Identities = 50/209 (23%), Positives = 90/209 (43%), Gaps = 20/209 (9%)
Query: 1481 PTNTASPPSSPH-----EEEFIDWWSKFFASIGE--REKCGSYLEKDFDTLKVYDTQLEN 1533
P S S P+ ++E + + + S+G E+ +L DF L Y +
Sbjct: 18 PAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHLPLDFHQLAFYVLDEDT 77
Query: 1534 VEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLA 1593
V G D L R + T DP I + L ++ P D + Q+
Sbjct: 78 V----GHDDIIGKISLSR---EAITADPRGIDSWINLSRVDP---DAEVQGEICLSVQML 127
Query: 1594 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1653
G CL R +++ A L P+D +G DP+ ++ G +S+ + + I T P + ++
Sbjct: 128 EDGQGRCL-RCHVLHARDLAPRDISGTSDPFARVFWGSQSL--ETSTIKKTRFPHWDEVL 184
Query: 1654 ELTCTLPLEKDLKITLYDYDLLSKDEKIG 1682
EL L++ L+D+D++ K++ +G
Sbjct: 185 ELREMPGAPSPLRVELWDWDMVGKNDFLG 213
Score = 43.5 bits (101), Expect = 0.002
Identities = 59/268 (22%), Positives = 100/268 (37%), Gaps = 64/268 (23%)
Query: 223 IRVQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPG 276
+ V+V+EGR LP ++ +VKV + + + P + E +L
Sbjct: 7 LNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHL----- 61
Query: 277 ELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLS--DPDDFSAGA 334
L + V+D ++ D ++G+ + I +PR + W+ LS DPD A
Sbjct: 62 PLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRG--IDSWINLSRVDPD---AEV 116
Query: 335 RGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQ 394
+G + S+ +L ED + LR V A DL
Sbjct: 117 QGEICLSVQML-----------------EDGQGRCLR------------CHVLHARDLAP 147
Query: 395 MDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFP 454
D + DPF V + + L + ++KT P W++ + L M P
Sbjct: 148 RDIS----------------GTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREM-P 190
Query: 455 SMCEKMRIRIIDWDRLTHNDIVATTYLS 482
+R+ + DWD + ND + S
Sbjct: 191 GAPSPLRVELWDWDMVGKNDFLGMVEFS 218
Score = 35.0 bits (79), Expect = 0.77
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
Query: 2 LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEW-DLKGIPL 60
L C ++ A +L SDP A + + T IK + P W+E E ++ G P
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAP- 193
Query: 61 DQGSELHVVVKDHETMGRNRFLG 83
S L V + D + +G+N FLG
Sbjct: 194 ---SPLRVELWDWDMVGKNDFLG 213
>gi|14149680 extended synaptotagmin-like protein 1 [Homo sapiens]
Length = 1104
Score = 56.6 bits (135), Expect = 2e-07
Identities = 103/467 (22%), Positives = 175/467 (37%), Gaps = 118/467 (25%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
+L L RA +LP K ++ +P+ L+ + V + +K + ++ PVW E F + L+
Sbjct: 479 ILVVYLDRAQDLPLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQD--- 535
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGA---- 116
Q EL V VKD R LG +PL +L P L +LD Q + +
Sbjct: 536 PQSQELDVQVKDD---SRALTLGALTLPLARLLTAPEL-------ILDQWFQLSSSGPNS 585
Query: 117 ----SLVLQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAE 172
LV+++ Y L + F PT+P D E
Sbjct: 586 RLYMKLVMRILY--LDSSEICF---------PTVPGCPGAWDVDSE-------------- 620
Query: 173 PFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQ 232
+ G PR + P + + +R+ V+E +
Sbjct: 621 ---NPQRGSSVDAPPRPCHTTPDSQF-------------------GTEHVLRIHVLEAQD 658
Query: 233 L------PGVNIK----PVVKVTAAGQTKRTRIHKGN-SPLFNETLFFNLFDSPGELFDE 281
L G +K P VK+ AG++ R+ + + + +P +NE + PG+ +
Sbjct: 659 LIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEV 718
Query: 282 PIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTS 341
+F + L D LG ++ + T+ +L +WL L D G L
Sbjct: 719 EVF-----DKDLDKDDFLGRCKVRLTTVLNS---GFLDEWLTLEDVPS------GRLHLR 764
Query: 342 LCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVF--RAEDLPQMDDAV 399
L L P R +E +E ++ N L T + A L ++ RAEDLP
Sbjct: 765 LERLTP-------RPTAAELEEVLQVNSLIQTQKSAELAAALLSIYMERAEDLP------ 811
Query: 400 MDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQN 446
K+L P+ ++ +K + +T+ P W+++
Sbjct: 812 ---------LRKGTKHL-SPYATLTVGDSSHKTKTISQTSAPVWDES 848
Score = 48.1 bits (113), Expect = 9e-05
Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 16/102 (15%)
Query: 1149 YGNRYHLRCYMYQARDLAAMDK------DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQ 1202
+G + LR ++ +A+DL A D+ SDPY + +S ++ VV+ LNP W++
Sbjct: 643 FGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNE 702
Query: 1203 TLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1244
+E+ + P E VE++D D D+F+GRC
Sbjct: 703 V---FEVIVTSVPGQELE------VEVFDKD-LDKDDFLGRC 734
Score = 47.0 bits (110), Expect = 2e-04
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 10/123 (8%)
Query: 1581 AIPMPPRQFHQLA-AQGPQECLVRIYIVRAFGLQPKDP------NGKCDPYIKISIGKKS 1633
++ PPR H +Q E ++RI+++ A L KD GK DPY+K+ + +S
Sbjct: 627 SVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRS 686
Query: 1634 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1693
+ + + L P + ++FE+ T ++L++ ++D D L KD+ +G V L L
Sbjct: 687 F--RSHVVREDLNPRWNEVFEVIVTSVPGQELEVEVFDKD-LDKDDFLGRCKVRLTTVLN 743
Query: 1694 SKF 1696
S F
Sbjct: 744 SGF 746
Score = 45.4 bits (106), Expect = 6e-04
Identities = 37/118 (31%), Positives = 55/118 (46%), Gaps = 18/118 (15%)
Query: 1155 LRCYMYQARDLAAMDK------DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYE 1208
+R ++ AR L++ DK + SDPYA+V Q+ + V+ LNP W +T YE
Sbjct: 331 IRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEELNPQWGET---YE 387
Query: 1209 IEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPS--LERMPRLAWFPLTRG 1264
+ + P I VE++D D D+F+GR L+ WFPL G
Sbjct: 388 VMVHEVPG------QEIEVEVFDKDP-DKDDFLGRMKLDVGKVLQASVLDDWFPLQGG 438
Score = 42.4 bits (98), Expect = 0.005
Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 14/98 (14%)
Query: 22 DPVASLTF-----RGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD--QGSELHVVVKDHE 74
DP SL RG K+RT K +++P +NE FEW+L PLD Q +L V VK +
Sbjct: 1007 DPYVSLLLLPDKNRGTKRRTSQKKRTLSPEFNERFEWEL---PLDEAQRRKLDVSVKSNS 1063
Query: 75 T-MGRNR-FLGEAKVPLREVLATPSLSASFNAPLLDTK 110
+ M R R LG+ ++ L E + ++ ++ L+D K
Sbjct: 1064 SFMSRERELLGKVQLDLAETDLSQGVARWYD--LMDNK 1099
Score = 37.7 bits (86), Expect = 0.12
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
+L + RA +LP K + P A+LT +TK I + PVW+E + ++ P
Sbjct: 799 LLSIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRK-PH 857
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSL 98
+ EL V E G LG +PL E+L L
Sbjct: 858 TESLELQV---RGEGTG---VLGSLSLPLSELLVADQL 889
Score = 34.7 bits (78), Expect = 1.0
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Query: 20 RSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRN 79
+SDP A + ++VI +NP W E +E + +P G E+ V V D + ++
Sbjct: 355 KSDPYALVRLGTQTFCSRVIDEELNPQWGETYEVMVHEVP---GQEIEVEVFDKDP-DKD 410
Query: 80 RFLGEAKVPLREVLATPSLSASF 102
FLG K+ + +VL L F
Sbjct: 411 DFLGRMKLDVGKVLQASVLDDWF 433
Score = 33.9 bits (76), Expect = 1.7
Identities = 17/52 (32%), Positives = 23/52 (44%)
Query: 1155 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIF 1206
L YM +A DL PYA ++ S KT + T P WD++ F
Sbjct: 800 LSIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASF 851
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 54.3 bits (129), Expect = 1e-06
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)
Query: 1128 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1172
S SVS G ++PT + +D GN L ++ QAR+L D +
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726
Query: 1173 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1218
+SDP+ V L + +VV+N +LNP W+QT+I+ I +
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780
Query: 1219 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1272
+ ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838
Query: 1273 ASFELIQREKPAI 1285
+S Q KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)
Query: 1604 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1651
I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770
Query: 1652 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1690
++ +K L++T++DYD S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812
Score = 38.9 bits (89), Expect = 0.054
Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 21/127 (16%)
Query: 33 KKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKVPLR 90
K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE + L
Sbjct: 4754 KRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDL- 4810
Query: 91 EVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPPPTP 139
S S N P K+ T G S Q S +P P + +FP P+
Sbjct: 4811 -----SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSK 4865
Query: 140 LEPSPTL 146
PT+
Sbjct: 4866 DMQVPTI 4872
Score = 36.6 bits (83), Expect = 0.27
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 432 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 487
+K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814
Score = 32.0 bits (71), Expect = 6.6
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 12/123 (9%)
Query: 112 QPTGASLVLQVSYTPLPGAV--PLFPPPTPLEPSPTL-PDLDVVADTGGEEDTEDQGLTG 168
QP+G + L PG V P+ PP T P+ L P TG E+ + +Q
Sbjct: 334 QPSGLTKPLAQQ----PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 169 DEAEP-----FLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQI 223
A+P Q GP P T + +P PG++ AP K +P +I
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 224 RVQ 226
Q
Sbjct: 450 PAQ 452
Score = 32.0 bits (71), Expect = 6.6
Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 39/160 (24%)
Query: 82 LGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPP----- 136
LG AK P ++ T S S P QP G V TP P PP
Sbjct: 366 LGPAKPPAQQ---TGSEKPSSEQPGPKALAQPPG------VGKTPAQQPGPAKPPTQQVG 416
Query: 137 -PTPLE-----------PSPTLPDLD------VVADTGGEEDTEDQGLTGDEAEPFLDQS 178
P PL P PT + + A G T Q TG P Q
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPP--SQL 473
Query: 179 GGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKP 218
GP P + P++PPP PG + P S++ S KP
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPG----SAKPPSQQPGSTKP 509
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 54.3 bits (129), Expect = 1e-06
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)
Query: 1128 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1172
S SVS G ++PT + +D GN L ++ QAR+L D +
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726
Query: 1173 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1218
+SDP+ V L + +VV+N +LNP W+QT+I+ I +
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780
Query: 1219 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1272
+ ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838
Query: 1273 ASFELIQREKPAI 1285
+S Q KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)
Query: 1604 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1651
I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770
Query: 1652 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1690
++ +K L++T++DYD S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812
Score = 38.9 bits (89), Expect = 0.054
Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 21/127 (16%)
Query: 33 KKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKVPLR 90
K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE + L
Sbjct: 4754 KRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDL- 4810
Query: 91 EVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPPPTP 139
S S N P K+ T G S Q S +P P + +FP P+
Sbjct: 4811 -----SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSK 4865
Query: 140 LEPSPTL 146
PT+
Sbjct: 4866 DMQVPTI 4872
Score = 36.6 bits (83), Expect = 0.27
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 432 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 487
+K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814
Score = 32.0 bits (71), Expect = 6.6
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 12/123 (9%)
Query: 112 QPTGASLVLQVSYTPLPGAV--PLFPPPTPLEPSPTL-PDLDVVADTGGEEDTEDQGLTG 168
QP+G + L PG V P+ PP T P+ L P TG E+ + +Q
Sbjct: 334 QPSGLTKPLAQQ----PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 169 DEAEP-----FLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQI 223
A+P Q GP P T + +P PG++ AP K +P +I
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 224 RVQ 226
Q
Sbjct: 450 PAQ 452
Score = 32.0 bits (71), Expect = 6.6
Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 39/160 (24%)
Query: 82 LGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPP----- 136
LG AK P ++ T S S P QP G V TP P PP
Sbjct: 366 LGPAKPPAQQ---TGSEKPSSEQPGPKALAQPPG------VGKTPAQQPGPAKPPTQQVG 416
Query: 137 -PTPLE-----------PSPTLPDLD------VVADTGGEEDTEDQGLTGDEAEPFLDQS 178
P PL P PT + + A G T Q TG P Q
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPP--SQL 473
Query: 179 GGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKP 218
GP P + P++PPP PG + P S++ S KP
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPG----SAKPPSQQPGSTKP 509
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 1159 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1218
+ + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E
Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 306
Query: 1219 AEQPPSIVVELYDHDTYGADEFMGRC 1244
E+ I + +D D D+F+GRC
Sbjct: 307 -ERGGVIDITAWDKDAGKRDDFIGRC 331
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 1601 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1660
+V I ++ L+ D NG DPY+K +G + + +P TL P + + F+
Sbjct: 250 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 307
Query: 1661 LEKDLKITLYDYDLLSKDEKIGETVVDL 1688
+ IT +D D +D+ IG VDL
Sbjct: 308 RGGVIDITAWDKDAGKRDDFIGRCQVDL 335
Score = 42.4 bits (98), Expect = 0.005
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
++RA L +A +SDP + + T + ++NP WN+ F +++K D S
Sbjct: 411 VIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----DIHSV 466
Query: 66 LHVVVKDHETMGRNRFLGEAKVPLREV 92
L V V D + FLG+ +PL +
Sbjct: 467 LEVTVYDEDRDRSADFLGKVAIPLLSI 493
Score = 41.2 bits (95), Expect = 0.011
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 1604 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1661
I + R L +D G DPY+K IG K V + I L PV+ E C L L
Sbjct: 44 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 99
Query: 1662 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1695
+ L I ++DYD +D+ +G +DL L++
Sbjct: 100 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 133
Score = 38.9 bits (89), Expect = 0.054
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 1585 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1644
P R FH L G +++ ++RA GL D GK DP+ + + + Y
Sbjct: 394 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 447
Query: 1645 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1688
L P + K+F + L++T+YD D + +G+ + L
Sbjct: 448 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 490
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 418 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 476
DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D +
Sbjct: 62 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 119
Query: 477 ATTYLSMSKI 486
+ +L ++++
Sbjct: 120 GSAFLDLTQL 129
Score = 37.7 bits (86), Expect = 0.12
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
L+ +L + + SDP K ++K++ ++NP W E F++ L ++G
Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGV 311
Query: 66 LHVVVKDHETMGRNRFLGEAKVPL 89
+ + D + R+ F+G +V L
Sbjct: 312 IDITAWDKDAGKRDDFIGRCQVDL 335
Score = 35.0 bits (79), Expect = 0.77
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 1155 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1214
L+ + +A L A D SDP+ +V + T V LNP W++ F
Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 458
Query: 1215 PATVAEQPPSIVVELYDHDTYGADEFMGR 1243
+ + + V +YD D + +F+G+
Sbjct: 459 --NIKDIHSVLEVTVYDEDRDRSADFLGK 485
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 1153 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1209
Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ +
Sbjct: 40 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 96
Query: 1210 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1242
+ EP + ++++D+D D+FMG
Sbjct: 97 DHLREP---------LYIKVFDYDFGLQDDFMG 120
Score = 32.0 bits (71), Expect = 6.6
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 412 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 471
+ L DP+V+ + SKI+ KT NPQW + ++ + I D D
Sbjct: 265 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 323
Query: 472 HNDIVATTYLSMSKIS 487
+D + + +S +S
Sbjct: 324 RDDFIGRCQVDLSALS 339
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 1159 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1218
+ + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E
Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 527
Query: 1219 AEQPPSIVVELYDHDTYGADEFMGRC 1244
E+ I + +D D D+F+GRC
Sbjct: 528 -ERGGVIDITAWDKDAGKRDDFIGRC 552
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 1601 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1660
+V I ++ L+ D NG DPY+K +G + + +P TL P + + F+
Sbjct: 471 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 528
Query: 1661 LEKDLKITLYDYDLLSKDEKIGETVVDL 1688
+ IT +D D +D+ IG VDL
Sbjct: 529 RGGVIDITAWDKDAGKRDDFIGRCQVDL 556
Score = 42.4 bits (98), Expect = 0.005
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
++RA L +A +SDP + + T + ++NP WN+ F +++K D S
Sbjct: 632 VIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----DIHSV 687
Query: 66 LHVVVKDHETMGRNRFLGEAKVPLREV 92
L V V D + FLG+ +PL +
Sbjct: 688 LEVTVYDEDRDRSADFLGKVAIPLLSI 714
Score = 41.2 bits (95), Expect = 0.011
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 1604 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1661
I + R L +D G DPY+K IG K V + I L PV+ E C L L
Sbjct: 265 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 320
Query: 1662 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1695
+ L I ++DYD +D+ +G +DL L++
Sbjct: 321 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 354
Score = 38.9 bits (89), Expect = 0.054
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 1585 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1644
P R FH L G +++ ++RA GL D GK DP+ + + + Y
Sbjct: 615 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 668
Query: 1645 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1688
L P + K+F + L++T+YD D + +G+ + L
Sbjct: 669 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 711
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 418 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 476
DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D +
Sbjct: 283 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 340
Query: 477 ATTYLSMSKI 486
+ +L ++++
Sbjct: 341 GSAFLDLTQL 350
Score = 37.7 bits (86), Expect = 0.12
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
L+ +L + + SDP K ++K++ ++NP W E F++ L ++G
Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGV 532
Query: 66 LHVVVKDHETMGRNRFLGEAKVPL 89
+ + D + R+ F+G +V L
Sbjct: 533 IDITAWDKDAGKRDDFIGRCQVDL 556
Score = 35.0 bits (79), Expect = 0.77
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 1155 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1214
L+ + +A L A D SDP+ +V + T V LNP W++ F
Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 679
Query: 1215 PATVAEQPPSIVVELYDHDTYGADEFMGR 1243
+ + + V +YD D + +F+G+
Sbjct: 680 --NIKDIHSVLEVTVYDEDRDRSADFLGK 706
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 1153 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1209
Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ +
Sbjct: 261 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 317
Query: 1210 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1242
+ EP + ++++D+D D+FMG
Sbjct: 318 DHLREP---------LYIKVFDYDFGLQDDFMG 341
Score = 32.0 bits (71), Expect = 6.6
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 412 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 471
+ L DP+V+ + SKI+ KT NPQW + ++ + I D D
Sbjct: 486 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 544
Query: 472 HNDIVATTYLSMSKIS 487
+D + + +S +S
Sbjct: 545 RDDFIGRCQVDLSALS 560
>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 731
Score = 53.1 bits (126), Expect = 3e-06
Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 1155 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1214
LRC + +ARDLA D++ SDP+ V + ++++T +VK + P W++T +E E+ E
Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 118
Query: 1215 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1261
A A + VE +D D ++F+G+ + R+ + WF L
Sbjct: 119 GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 162
Score = 48.9 bits (115), Expect = 5e-05
Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 2 LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 61
L C ++ A +L ++ SDP + ++G + T ++K S P WNE FE++L+ ++
Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 122
Query: 62 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 92
L V D + + RN FLG+ + ++ +
Sbjct: 123 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 150
Score = 48.5 bits (114), Expect = 7e-05
Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 1596 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1655
G + C +R ++ A L PKD NG DP++++ K + + + + + P + + FE
Sbjct: 57 GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 114
Query: 1656 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1689
+ L + +D+DL+S+++ +G+ V+D++
Sbjct: 115 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 148
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/136 (22%), Positives = 53/136 (38%), Gaps = 18/136 (13%)
Query: 351 APLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFE 410
A L DP E+ + E +L R V A DL D
Sbjct: 33 AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-------------- 77
Query: 411 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRL 470
+ DPFV V + G+ + I++K+ P+WN+ +M E + + DWD +
Sbjct: 78 --RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-EALCVEAWDWDLV 134
Query: 471 THNDIVATTYLSMSKI 486
+ ND + + + ++
Sbjct: 135 SRNDFLGKVVIDVQRL 150
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,429,374
Number of Sequences: 37866
Number of extensions: 4695019
Number of successful extensions: 16982
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 14643
Number of HSP's gapped (non-prelim): 1781
length of query: 2102
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1984
effective length of database: 13,779,330
effective search space: 27338190720
effective search space used: 27338190720
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.