Guide to the Human Genome
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Search of human proteins with 195976766

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195976766 dysferlin isoform 7 [Homo sapiens]
         (2112 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195976766 dysferlin isoform 7 [Homo sapiens]                      4350   0.0  
gi|195976775 dysferlin isoform 4 [Homo sapiens]                      4313   0.0  
gi|195976779 dysferlin isoform 1 [Homo sapiens]                      4300   0.0  
gi|195976760 dysferlin isoform 12 [Homo sapiens]                     4299   0.0  
gi|195976821 dysferlin isoform 2 [Homo sapiens]                      4269   0.0  
gi|195976762 dysferlin isoform 13 [Homo sapiens]                     4262   0.0  
gi|195976769 dysferlin isoform 6 [Homo sapiens]                      4256   0.0  
gi|195976764 dysferlin isoform 14 [Homo sapiens]                     4249   0.0  
gi|195976777 dysferlin isoform 3 [Homo sapiens]                      4231   0.0  
gi|195976773 dysferlin isoform 5 [Homo sapiens]                      4219   0.0  
gi|4503431 dysferlin isoform 8 [Homo sapiens]                        4218   0.0  
gi|195976758 dysferlin isoform 11 [Homo sapiens]                     4205   0.0  
gi|195976754 dysferlin isoform 9 [Homo sapiens]                      4180   0.0  
gi|195976756 dysferlin isoform 10 [Homo sapiens]                     4168   0.0  
gi|7305053 myoferlin isoform a [Homo sapiens]                        2376   0.0  
gi|19718759 myoferlin isoform b [Homo sapiens]                       2374   0.0  
gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]                   1401   0.0  
gi|35493868 otoferlin isoform b [Homo sapiens]                        720   0.0  
gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]                    714   0.0  
gi|35493853 otoferlin isoform c [Homo sapiens]                        712   0.0  
gi|35493860 otoferlin isoform d [Homo sapiens]                        712   0.0  
gi|34740331 otoferlin isoform a [Homo sapiens]                        712   0.0  
gi|119120884 fer-1-like 6 [Homo sapiens]                              709   0.0  
gi|4759026 RAS protein activator like 1 [Homo sapiens]                 65   5e-10
gi|150170670 piccolo isoform 2 [Homo sapiens]                          54   1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          54   1e-06
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo...    54   2e-06
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom...    54   2e-06
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva...    53   3e-06
gi|239743307 PREDICTED: similar to calcium-promoted Ras inactiva...    53   3e-06

>gi|195976766 dysferlin isoform 7 [Homo sapiens]
          Length = 2112

 Score = 4350 bits (11283), Expect = 0.0
 Identities = 2112/2112 (100%), Positives = 2112/2112 (100%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
            PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500

Query: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
            IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560

Query: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
            RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620

Query: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
            GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680

Query: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
            DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740

Query: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
            HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800

Query: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
            PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860

Query: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
            SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920

Query: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
            KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980

Query: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
            DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040

Query: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
            PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100

Query: 2101 NYAAMKLVKPFS 2112
            NYAAMKLVKPFS
Sbjct: 2101 NYAAMKLVKPFS 2112


>gi|195976775 dysferlin isoform 4 [Homo sapiens]
          Length = 2098

 Score = 4313 bits (11185), Expect = 0.0
 Identities = 2097/2112 (99%), Positives = 2098/2112 (99%), Gaps = 14/2112 (0%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
            PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 527  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 587  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 647  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 707  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 767  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 827  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 887  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 947  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486

Query: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
            IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1487 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1546

Query: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
            RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1547 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1606

Query: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
            GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1607 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1666

Query: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
            DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1667 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1726

Query: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
            HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1727 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1786

Query: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
            PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1787 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1846

Query: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
            SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1847 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1906

Query: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
            KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1907 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1966

Query: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
            DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1967 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2026

Query: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
            PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2027 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2086

Query: 2101 NYAAMKLVKPFS 2112
            NYAAMKLVKPFS
Sbjct: 2087 NYAAMKLVKPFS 2098


>gi|195976779 dysferlin isoform 1 [Homo sapiens]
          Length = 2119

 Score = 4300 bits (11153), Expect = 0.0
 Identities = 2097/2133 (98%), Positives = 2098/2133 (98%), Gaps = 35/2133 (1%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
            PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 527  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 587  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 647  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 707  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 767  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 827  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 887  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 947  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486

Query: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539
            IQ                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1487 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1546

Query: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599
            QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1547 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1606

Query: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659
            HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1607 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1666

Query: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719
            GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1667 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1726

Query: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779
            GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1727 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1786

Query: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839
            ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1787 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1846

Query: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899
            ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1847 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1906

Query: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959
            NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1907 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1966

Query: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019
            DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1967 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2026

Query: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079
            TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2027 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2086

Query: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112
            ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2087 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2119


>gi|195976760 dysferlin isoform 12 [Homo sapiens]
          Length = 2111

 Score = 4299 bits (11151), Expect = 0.0
 Identities = 2091/2112 (99%), Positives = 2095/2112 (99%), Gaps = 1/2112 (0%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
            PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 480  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 539

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 540  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 599

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 600  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 659

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 660  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 719

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 720  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 779

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 780  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 839

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 840  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 899

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 900  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 959

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 960  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1019

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1020 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1079

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1080 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1139

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1140 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1199

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1200 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1259

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1260 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1319

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1320 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1379

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1380 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1439

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1440 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1499

Query: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
            IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1500 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1559

Query: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
            RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1560 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1619

Query: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
            GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1620 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1679

Query: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
            DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1680 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1739

Query: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
            HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1740 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1799

Query: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
            PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1800 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1859

Query: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
            SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1860 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1919

Query: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
            KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1920 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1979

Query: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
            DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1980 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2039

Query: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
            PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2040 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2099

Query: 2101 NYAAMKLVKPFS 2112
            NYAAMKLVKPFS
Sbjct: 2100 NYAAMKLVKPFS 2111


>gi|195976821 dysferlin isoform 2 [Homo sapiens]
          Length = 2081

 Score = 4269 bits (11071), Expect = 0.0
 Identities = 2081/2112 (98%), Positives = 2081/2112 (98%), Gaps = 31/2112 (1%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 450  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 510  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 570  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 630  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 690  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 750  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 810  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 870  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 930  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 990  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469

Query: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
            IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1470 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1529

Query: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
            RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1530 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1589

Query: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
            GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1590 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1649

Query: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
            DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1650 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1709

Query: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
            HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1710 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1769

Query: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
            PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1770 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1829

Query: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
            SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1830 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1889

Query: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
            KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1890 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1949

Query: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
            DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1950 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2009

Query: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
            PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2010 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2069

Query: 2101 NYAAMKLVKPFS 2112
            NYAAMKLVKPFS
Sbjct: 2070 NYAAMKLVKPFS 2081


>gi|195976762 dysferlin isoform 13 [Homo sapiens]
          Length = 2097

 Score = 4262 bits (11053), Expect = 0.0
 Identities = 2076/2112 (98%), Positives = 2081/2112 (98%), Gaps = 15/2112 (0%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
            PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 480  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 525

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 526  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 585

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 586  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 645

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 646  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 705

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 706  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 766  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 826  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 886  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 945

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 946  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1005

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1006 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1065

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1066 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1125

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1126 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1185

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1186 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1245

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1246 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1305

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1306 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1365

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1366 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1425

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1426 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1485

Query: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
            IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1486 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1545

Query: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
            RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1546 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1605

Query: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
            GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1606 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1665

Query: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
            DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1666 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1725

Query: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
            HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1726 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1785

Query: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
            PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1786 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1845

Query: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
            SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1846 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1905

Query: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
            KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1906 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1965

Query: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
            DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1966 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2025

Query: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
            PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2026 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2085

Query: 2101 NYAAMKLVKPFS 2112
            NYAAMKLVKPFS
Sbjct: 2086 NYAAMKLVKPFS 2097


>gi|195976769 dysferlin isoform 6 [Homo sapiens]
          Length = 2102

 Score = 4256 bits (11039), Expect = 0.0
 Identities = 2081/2133 (97%), Positives = 2081/2133 (97%), Gaps = 52/2133 (2%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 450  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 510  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 570  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 630  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 690  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 750  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 810  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 870  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 930  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 990  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469

Query: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539
            IQ                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529

Query: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599
            QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589

Query: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659
            HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649

Query: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719
            GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709

Query: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779
            GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769

Query: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839
            ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829

Query: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899
            ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889

Query: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959
            NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949

Query: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019
            DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009

Query: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079
            TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069

Query: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112
            ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102


>gi|195976764 dysferlin isoform 14 [Homo sapiens]
          Length = 2118

 Score = 4249 bits (11021), Expect = 0.0
 Identities = 2076/2133 (97%), Positives = 2081/2133 (97%), Gaps = 36/2133 (1%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
            PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 480  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 525

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 526  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 585

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 586  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 645

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 646  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 705

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 706  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 766  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 826  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 886  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 945

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 946  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1005

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1006 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1065

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1066 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1125

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1126 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1185

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1186 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1245

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1246 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1305

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1306 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1365

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1366 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1425

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1426 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1485

Query: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539
            IQ                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1486 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1545

Query: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599
            QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1546 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1605

Query: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659
            HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1606 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1665

Query: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719
            GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1666 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1725

Query: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779
            GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1726 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1785

Query: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839
            ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1786 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1845

Query: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899
            ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1846 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1905

Query: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959
            NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1906 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1965

Query: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019
            DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1966 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2025

Query: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079
            TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2026 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2085

Query: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112
            ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2086 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2118


>gi|195976777 dysferlin isoform 3 [Homo sapiens]
          Length = 2067

 Score = 4231 bits (10973), Expect = 0.0
 Identities = 2066/2112 (97%), Positives = 2067/2112 (97%), Gaps = 45/2112 (2%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 450  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 495

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 496  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 555

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 556  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 615

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 616  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 675

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 676  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 735

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 736  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 795

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 796  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 855

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 856  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 915

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 916  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 975

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 976  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1035

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1036 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1095

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1096 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1155

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1156 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1215

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1216 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1275

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1276 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1335

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1336 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1395

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1396 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1455

Query: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
            IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1456 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1515

Query: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
            RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1516 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1575

Query: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
            GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1576 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1635

Query: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
            DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1636 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1695

Query: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
            HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1696 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1755

Query: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
            PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1756 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1815

Query: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
            SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1816 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1875

Query: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
            KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1876 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1935

Query: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
            DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1936 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 1995

Query: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
            PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 1996 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2055

Query: 2101 NYAAMKLVKPFS 2112
            NYAAMKLVKPFS
Sbjct: 2056 NYAAMKLVKPFS 2067


>gi|195976773 dysferlin isoform 5 [Homo sapiens]
          Length = 2088

 Score = 4219 bits (10941), Expect = 0.0
 Identities = 2066/2133 (96%), Positives = 2067/2133 (96%), Gaps = 66/2133 (3%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 450  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 495

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 496  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 555

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 556  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 615

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 616  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 675

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 676  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 735

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 736  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 795

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 796  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 855

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 856  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 915

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 916  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 975

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 976  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1035

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1036 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1095

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1096 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1155

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1156 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1215

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1216 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1275

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1276 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1335

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1336 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1395

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1396 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1455

Query: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539
            IQ                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1456 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1515

Query: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599
            QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1516 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1575

Query: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659
            HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1576 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1635

Query: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719
            GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1636 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1695

Query: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779
            GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1696 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1755

Query: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839
            ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1756 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1815

Query: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899
            ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1816 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1875

Query: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959
            NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1876 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1935

Query: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019
            DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1936 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 1995

Query: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079
            TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 1996 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2055

Query: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112
            ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2056 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088


>gi|4503431 dysferlin isoform 8 [Homo sapiens]
          Length = 2080

 Score = 4218 bits (10939), Expect = 0.0
 Identities = 2060/2112 (97%), Positives = 2064/2112 (97%), Gaps = 32/2112 (1%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 153  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 209  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 269  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 329  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 389  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 449  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 508

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 509  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 568

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 569  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 628

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 629  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 688

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 689  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 748

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 749  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 808

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 809  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 868

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 869  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 928

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 929  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 988

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 989  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1048

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1049 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1108

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1109 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1168

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1169 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1228

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1229 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1288

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1289 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1348

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1349 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1408

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1409 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1468

Query: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
            IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1469 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1528

Query: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
            RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1529 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1588

Query: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
            GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1589 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1648

Query: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
            DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1649 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1708

Query: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
            HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1709 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1768

Query: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
            PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1769 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1828

Query: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
            SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1829 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1888

Query: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
            KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1889 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1948

Query: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
            DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1949 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2008

Query: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
            PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2009 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2068

Query: 2101 NYAAMKLVKPFS 2112
            NYAAMKLVKPFS
Sbjct: 2069 NYAAMKLVKPFS 2080


>gi|195976758 dysferlin isoform 11 [Homo sapiens]
          Length = 2101

 Score = 4205 bits (10907), Expect = 0.0
 Identities = 2060/2133 (96%), Positives = 2064/2133 (96%), Gaps = 53/2133 (2%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 153  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 209  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 269  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 329  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 389  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 449  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 508

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 509  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 568

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 569  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 628

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 629  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 688

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 689  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 748

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 749  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 808

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 809  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 868

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 869  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 928

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 929  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 988

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 989  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1048

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1049 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1108

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1109 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1168

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1169 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1228

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1229 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1288

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1289 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1348

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1349 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1408

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1409 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1468

Query: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539
            IQ                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1469 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1528

Query: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599
            QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1529 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1588

Query: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659
            HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1589 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1648

Query: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719
            GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1649 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1708

Query: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779
            GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1709 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1768

Query: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839
            ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1769 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1828

Query: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899
            ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1829 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1888

Query: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959
            NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1889 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1948

Query: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019
            DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1949 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2008

Query: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079
            TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2009 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2068

Query: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112
            ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2069 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2101


>gi|195976754 dysferlin isoform 9 [Homo sapiens]
          Length = 2066

 Score = 4180 bits (10841), Expect = 0.0
 Identities = 2045/2112 (96%), Positives = 2050/2112 (97%), Gaps = 46/2112 (2%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 153  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 209  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 269  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 329  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 389  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 449  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 494

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 495  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 554

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 555  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 614

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 615  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 674

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 675  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 734

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 735  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 794

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 795  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 854

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 855  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 914

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 915  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 974

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 975  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1034

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1035 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1094

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1095 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1154

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1155 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1214

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1215 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1274

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1275 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1334

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1335 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1394

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1395 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1454

Query: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
            IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1455 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1514

Query: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
            RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1515 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1574

Query: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
            GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1575 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1634

Query: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
            DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1635 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1694

Query: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
            HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1695 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1754

Query: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
            PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1755 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1814

Query: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
            SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1815 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1874

Query: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
            KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1875 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1934

Query: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
            DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1935 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 1994

Query: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
            PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 1995 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2054

Query: 2101 NYAAMKLVKPFS 2112
            NYAAMKLVKPFS
Sbjct: 2055 NYAAMKLVKPFS 2066


>gi|195976756 dysferlin isoform 10 [Homo sapiens]
          Length = 2087

 Score = 4168 bits (10809), Expect = 0.0
 Identities = 2045/2133 (95%), Positives = 2050/2133 (96%), Gaps = 67/2133 (3%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119

Query: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152

Query: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 153  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208

Query: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 209  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268

Query: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 269  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328

Query: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 329  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388

Query: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 389  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448

Query: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 449  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 494

Query: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 495  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 554

Query: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 555  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 614

Query: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 615  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 674

Query: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 675  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 734

Query: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 735  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 794

Query: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 795  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 854

Query: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 855  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 914

Query: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 915  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 974

Query: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 975  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1034

Query: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1035 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1094

Query: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1095 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1154

Query: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1155 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1214

Query: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1215 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1274

Query: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1275 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1334

Query: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1335 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1394

Query: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1395 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1454

Query: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539
            IQ                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1455 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1514

Query: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599
            QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1515 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1574

Query: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659
            HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1575 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1634

Query: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719
            GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1635 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1694

Query: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779
            GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1695 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1754

Query: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839
            ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1755 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1814

Query: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899
            ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1815 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1874

Query: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959
            NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1875 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1934

Query: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019
            DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1935 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 1994

Query: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079
            TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 1995 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2054

Query: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112
            ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2055 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087


>gi|7305053 myoferlin isoform a [Homo sapiens]
          Length = 2061

 Score = 2376 bits (6157), Expect = 0.0
 Identities = 1179/2140 (55%), Positives = 1522/2140 (71%), Gaps = 111/2140 (5%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML  ++  ASN+P  K  +  DP+ S+ F+  KK+TK + N +NPVWNE  E+DL+GIPL
Sbjct: 1    MLRVIVESASNIPKTKFGK-PDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLV 119
            D  S L ++VKD ET+G+N+ +G A V L+++    S S  +    LL+ K Q TGA++ 
Sbjct: 60   DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATID 119

Query: 120  LQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKK 179
            L + Y P     P  P P  L   P++P +     GG    +                  
Sbjct: 120  LVIGYDP-----PSAPHPNDLS-GPSVPGM-----GGDGEEDE----------------- 151

Query: 180  WPAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAP 239
                    G+ED  D  + G   +       GP    +  +L           +R     
Sbjct: 152  --------GDEDRLDNAVRGPGPK-------GPVGTVSEAQLA----------RRLTKVK 186

Query: 240  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299
             SR++LS+KPQDFQIRV+VIEGRQL G NI+PVVKV   GQT RTRI +GN+P F+E  F
Sbjct: 187  NSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFF 246

Query: 300  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359
            +N+  +P EL DE I I V +S SLR D L+GEF++DVG +Y EP HA +RKWLLL+DP+
Sbjct: 247  YNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPE 306

Query: 360  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419
            D S+G++GY+K S+ VLG GDE P ER+D   D +D+ESNLL P G+ALR   F LK++R
Sbjct: 307  DTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYR 366

Query: 420  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479
            AED+PQMDDA    VK+IFG  ++KKNLVDPFVEVSFAGK +C+ I+EK ANP+WNQ + 
Sbjct: 367  AEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVN 426

Query: 480  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSK--A 537
            L   FPS+CEK+++ I DWDRLT ND+V TTYL +SKI+A GGE+E+  +     +    
Sbjct: 427  LQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEDFSSSGTGAASYTV 486

Query: 538  SDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLV 597
            +  +  +GF+PTFGPCY+NLYGSPRE+TGFPDPY ELNTGKGEGVAYRGR+L+ L T L 
Sbjct: 487  NTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLE 546

Query: 598  E-HSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKF 656
            +   ++K+E +  DD+L VEKY RRRKYSL A F+SATMLQDV +AIQFEVSIGNYGNKF
Sbjct: 547  KTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKF 606

Query: 657  DMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADR 716
            D TC PLASTTQYSRAVFDG +YYYLPW + KPVV L+SYWEDISHR++  N LL +A+R
Sbjct: 607  DTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAER 666

Query: 717  LEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLR 776
            L+  +E +   ++ +     +  L  +L DE+I      L       + T LD  + +LR
Sbjct: 667  LQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLR 726

Query: 777  THHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRV 836
            +  LSQI EAA+ ++   +++ + L + EDWL +L  L EEPQNS+PDI+IWM++G+KR+
Sbjct: 727  SRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRL 786

Query: 837  AYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDE 896
            AY R+PAHQVL+S  G N  GK CGK QTIFLKYP EK  G ++PV++RV +W GLS  E
Sbjct: 787  AYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVE 846

Query: 897  KEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT-YPKFSDVTGKIKLPKDSFRPSAG 955
            K+FN FAEG  +VFAE YEN+    + G WGT+GL    KFSDVTGKIKL ++ F P  G
Sbjct: 847  KKFNSFAEGTFTVFAEMYENQA--LMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKG 904

Query: 956  WTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPK 1015
            W W G+W V PE++LL + DAGH  F +EV++N++R PGG W    D YTD NG+K    
Sbjct: 905  WEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASP 964

Query: 1016 DDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWV 1075
             ++ CP GW+WED+ WS D+NRAVDE+GWEY ITIPP+ KPK WV AEKMY+THRRRR V
Sbjct: 965  SELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLV 1024

Query: 1076 RLRRRDLSQMEALKRHRQAEAEG-EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLE 1134
            R R++DL+Q  +       E +  EGWEYASL GWKFH + R +D FRRRRWRR+M P E
Sbjct: 1025 RKRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSE 1084

Query: 1135 KTGPAAVFALEGALGGVM----DDKS-EDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCY 1189
              G AA+F LEGALG       D+KS E     +T  FG N P +SC FD    YHLRCY
Sbjct: 1085 THGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCY 1144

Query: 1190 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1249
            +YQAR+L A+DKDSFSDPYA + FLH+S+ T ++ +TLNPTWDQT+IF E+EI+GEP TV
Sbjct: 1145 VYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTV 1204

Query: 1250 AEQPPSIVVELYDHDTYGADEFMGRCICQP------SLERMPRLAWFPLTRGSQPSGELL 1303
             + PP +++EL+D+D  G DEF+GR I  P       ++  P+L W P+  G +  G++L
Sbjct: 1205 LQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVL 1264

Query: 1304 ASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQR 1363
             + ELI R K                     + ++LP  PPQR  N+YMVPQ I+P +Q 
Sbjct: 1265 VTAELILRGK---------------------DGSNLPILPPQRAPNLYMVPQGIRPVVQL 1303

Query: 1364 TAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVML 1423
            TAIEILAWGLRNMK++Q+A+I+SPSLVVECGG+ V+S VI+NL+K PNF    LFM+V L
Sbjct: 1304 TAIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFL 1363

Query: 1424 PREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSA-ESPSPQGGPDDVSLL 1482
            P+EELY PP+ +KVID+RQFGR+PVVGQCTI  L+ F CDPY+  E   PQ      SLL
Sbjct: 1364 PKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQ---LKASLL 1420

Query: 1483 S--PGEDVLIDIDDKEPLIPI----QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKV 1536
            S  P  D++I+++D +PL+      +EEE +DWWSKF+AS GE EKCG Y++K +  LK+
Sbjct: 1421 SAPPCRDIVIEMEDTKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKI 1480

Query: 1537 YDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPP 1596
            Y+ +LENV  FEGL+DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PP
Sbjct: 1481 YNCELENVAEFEGLTDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPP 1539

Query: 1597 RQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1656
            RQF +L    PQEC VRIYIVR   LQP+D NG CDPYIKI++GKK + D+D+YIP TL 
Sbjct: 1540 RQFRELPDSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLN 1599

Query: 1657 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1716
            PVFG+M+EL+C LP EKDLKI++YDYD  ++DEK+GET++DLENR LS+FG+ CG+P+ Y
Sbjct: 1600 PVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEY 1659

Query: 1717 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPH 1774
            CVSG N WRDQLRP+QLL    +      P+   D  R+ +  ++YS++E EA +I + H
Sbjct: 1660 CVSGVNTWRDQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQH 1719

Query: 1775 LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFN 1834
            LG  EERLALH+L+ QGLVPEHVE+R L+S  QP+I QGKLQMWVD+FPK+LG PGPPFN
Sbjct: 1720 LGAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFN 1779

Query: 1835 ITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLG 1894
            ITPR+A++++LR IIWNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL 
Sbjct: 1780 ITPRKAKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLD 1839

Query: 1895 GEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFL 1954
            GEGNFNWRF+FPFDYLPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+L
Sbjct: 1840 GEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYL 1899

Query: 1955 GSLQLDLNRMPKPAKTAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEK 2010
            G L+LDL     PAK+ +KC LD + D  A +P      SLFEQK++KGWWPC AE+   
Sbjct: 1900 GFLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGA 1959

Query: 2011 KILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFI 2070
            +++AGK+EMTLEI+ E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI
Sbjct: 1960 RVMAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFI 2019

Query: 2071 LWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2110
            +WRRF+W II  + L ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2020 VWRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKP 2059


>gi|19718759 myoferlin isoform b [Homo sapiens]
          Length = 2048

 Score = 2374 bits (6152), Expect = 0.0
 Identities = 1179/2138 (55%), Positives = 1518/2138 (71%), Gaps = 120/2138 (5%)

Query: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
            ML  ++  ASN+P  K  +  DP+ S+ F+  KK+TK + N +NPVWNE  E+DL+GIPL
Sbjct: 1    MLRVIVESASNIPKTKFGK-PDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPL 59

Query: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLV 119
            D  S L ++VKD ET+G+N+ +G A V L+++    S S  +    LL+ K Q TGA++ 
Sbjct: 60   DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATID 119

Query: 120  LQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKK 179
            L + Y P     P  P P  L   P++P +     GG    +                  
Sbjct: 120  LVIGYDP-----PSAPHPNDLS-GPSVPGM-----GGDGEEDE----------------- 151

Query: 180  WPAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAP 239
                    G+ED  D  + G   +       GP    +  +L           +R     
Sbjct: 152  --------GDEDRLDNAVRGPGPK-------GPVGTVSEAQLA----------RRLTKVK 186

Query: 240  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299
             SR++LS+KPQDFQIRV+VIEGRQL G NI+PVVKV   GQT RTRI +GN+P F+E  F
Sbjct: 187  NSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFF 246

Query: 300  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359
            +N+  +P EL DE I I V +S SLR D L+GEF++DVG +Y EP HA +RKWLLL+DP+
Sbjct: 247  YNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPE 306

Query: 360  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419
            D S+G++GY+K S+ VLG GDE P ER+D   D +D+ESNLL P G+ALR   F LK++R
Sbjct: 307  DTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYR 366

Query: 420  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479
            AED+PQMDDA    VK+IFG  ++KKNLVDPFVEVSFAGK +C+ I+EK ANP+WNQ + 
Sbjct: 367  AEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVN 426

Query: 480  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASD 539
            L   FPS+CEK+++ I DWDRLT ND+V TTYL +SKI+A GGE+E              
Sbjct: 427  LQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEVNTG---------- 476

Query: 540  LDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVE- 598
             +  +GF+PTFGPCY+NLYGSPRE+TGFPDPY ELNTGKGEGVAYRGR+L+ L T L + 
Sbjct: 477  -ETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKT 535

Query: 599  HSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDM 658
              ++K+E +  DD+L VEKY RRRKYSL A F+SATMLQDV +AIQFEVSIGNYGNKFD 
Sbjct: 536  PPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDT 595

Query: 659  TCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLE 718
            TC PLASTTQYSRAVFDG +YYYLPW + KPVV L+SYWEDISHR++  N LL +A+RL+
Sbjct: 596  TCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERLQ 655

Query: 719  AGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTH 778
              +E +   ++ +     +  L  +L DE+I      L       + T LD  + +LR+ 
Sbjct: 656  TNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLRSR 715

Query: 779  HLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAY 838
             LSQI EAA+ ++   +++ + L + EDWL +L  L EEPQNS+PDI+IWM++G+KR+AY
Sbjct: 716  SLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAY 775

Query: 839  QRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKE 898
             R+PAHQVL+S  G N  GK CGK QTIFLKYP EK  G ++PV++RV +W GLS  EK+
Sbjct: 776  ARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEKK 835

Query: 899  FNQFAEGKLSVFAETYENETKLALVGNWGTTGLT-YPKFSDVTGKIKLPKDSFRPSAGWT 957
            FN FAEG  +VFAE YEN+    + G WGT+GL    KFSDVTGKIKL ++ F P  GW 
Sbjct: 836  FNSFAEGTFTVFAEMYENQA--LMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWE 893

Query: 958  WAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDD 1017
            W G+W V PE++LL + DAGH  F +EV++N++R PGG W    D YTD NG+K     +
Sbjct: 894  WEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPSE 953

Query: 1018 IECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRL 1077
            + CP GW+WED+ WS D+NRAVDE+GWEY ITIPP+ KPK WV AEKMY+THRRRR VR 
Sbjct: 954  LTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVRK 1013

Query: 1078 RRRDLSQMEALKRHRQAEAEG-EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKT 1136
            R++DL+Q  +       E +  EGWEYASL GWKFH + R +D FRRRRWRR+M P E  
Sbjct: 1014 RKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETH 1073

Query: 1137 GPAAVFALEGALGGVM----DDKS-EDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMY 1191
            G AA+F LEGALG       D+KS E     +T  FG N P +SC FD    YHLRCY+Y
Sbjct: 1074 GAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYVY 1133

Query: 1192 QARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAE 1251
            QAR+L A+DKDSFSDPYA + FLH+S+ T ++ +TLNPTWDQT+IF E+EI+GEP TV +
Sbjct: 1134 QARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQ 1193

Query: 1252 QPPSIVVELYDHDTYGADEFMGRCICQP------SLERMPRLAWFPLTRGSQPSGELLAS 1305
             PP +++EL+D+D  G DEF+GR I  P       ++  P+L W P+  G +  G++L +
Sbjct: 1194 NPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVLVT 1253

Query: 1306 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1365
             ELI R K                     + ++LP  PPQR  N+YMVPQ I+P +Q TA
Sbjct: 1254 AELILRGK---------------------DGSNLPILPPQRAPNLYMVPQGIRPVVQLTA 1292

Query: 1366 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1425
            IEILAWGLRNMK++Q+A+I+SPSLVVECGG+ V+S VI+NL+K PNF    LFM+V LP+
Sbjct: 1293 IEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLPK 1352

Query: 1426 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSA-ESPSPQGGPDDVSLLS- 1483
            EELY PP+ +KVID+RQFGR+PVVGQCTI  L+ F CDPY+  E   PQ      SLLS 
Sbjct: 1353 EELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQ---LKASLLSA 1409

Query: 1484 -PGEDVLIDIDDKEPLIPI----QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1538
             P  D++I+++D +PL+      +EEE +DWWSKF+AS GE EKCG Y++K +  LK+Y+
Sbjct: 1410 PPCRDIVIEMEDTKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYN 1469

Query: 1539 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1598
             +LENV  FEGL+DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PPRQ
Sbjct: 1470 CELENVAEFEGLTDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQ 1528

Query: 1599 FHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPV 1658
            F +L    PQEC VRIYIVR   LQP+D NG CDPYIKI++GKK + D+D+YIP TL PV
Sbjct: 1529 FRELPDSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPV 1588

Query: 1659 FGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCV 1718
            FG+M+EL+C LP EKDLKI++YDYD  ++DEK+GET++DLENR LS+FG+ CG+P+ YCV
Sbjct: 1589 FGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCV 1648

Query: 1719 SGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLG 1776
            SG N WRDQLRP+QLL    +      P+   D  R+ +  ++YS++E EA +I + HLG
Sbjct: 1649 SGVNTWRDQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLG 1708

Query: 1777 PVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNIT 1836
              EERLALH+L+ QGLVPEHVE+R L+S  QP+I QGKLQMWVD+FPK+LG PGPPFNIT
Sbjct: 1709 APEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNIT 1768

Query: 1837 PRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGE 1896
            PR+A++++LR IIWNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GE
Sbjct: 1769 PRKAKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGE 1828

Query: 1897 GNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGS 1956
            GNFNWRF+FPFDYLPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+LG 
Sbjct: 1829 GNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGF 1888

Query: 1957 LQLDLNRMPKPAKTAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKI 2012
            L+LDL     PAK+ +KC LD + D  A +P      SLFEQK++KGWWPC AE+   ++
Sbjct: 1889 LELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARV 1948

Query: 2013 LAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILW 2072
            +AGK+EMTLEI+ E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+W
Sbjct: 1949 MAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVW 2008

Query: 2073 RRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2110
            RRF+W II  + L ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2009 RRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKP 2046


>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
          Length = 2093

 Score = 1401 bits (3627), Expect = 0.0
 Identities = 805/1973 (40%), Positives = 1133/1973 (57%), Gaps = 200/1973 (10%)

Query: 240  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299
            T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P FNE  F
Sbjct: 155  TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214

Query: 300  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359
             N  + P + FDE I I                 + D+G IY  P H  LRKWL L  P+
Sbjct: 215  QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257

Query: 360  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419
            +  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+  L ++ 
Sbjct: 258  NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316

Query: 420  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479
            AEDL                    K   V+P +EV   G+ L + +  +T NP WNQ +T
Sbjct: 317  AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359

Query: 480  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASD 539
                 P +   ++ R++D  +    D + T  LS+++IS+ G EIE + +  ++P+  + 
Sbjct: 360  FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQS--LEPTSYTP 417

Query: 540  LDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEH 599
               Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T++  +
Sbjct: 418  RV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSY 476

Query: 600  SEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMT 659
             +  ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK D+ 
Sbjct: 477  QDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLN 535

Query: 660  CLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEA 719
              PL S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    DRL+A
Sbjct: 536  YKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKA 595

Query: 720  GLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRT 777
             L+     LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +QLR+
Sbjct: 596  NLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRS 651

Query: 778  HHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVA 837
              L +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  ++RVA
Sbjct: 652  LLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVA 706

Query: 838  YQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEK 897
            Y +VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G   D K
Sbjct: 707  YAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSK 766

Query: 898  EFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGW 956
            +     +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P  GW
Sbjct: 767  DLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGW 824

Query: 957  TWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKD 1016
             W   W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +  ++
Sbjct: 825  HWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARE 884

Query: 1017 DIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVR 1076
            +++CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRRRW R
Sbjct: 885  NVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWAR 941

Query: 1077 LRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW 1126
            +R R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FRRR W
Sbjct: 942  VRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCW 996

Query: 1127 RRRMEPLEKTGPAAVFALEGAL----GGVMDD---------------------------- 1154
            RRR+ P +  G A +F LEG+L    G V ++                            
Sbjct: 997  RRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDL 1056

Query: 1155 -----KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQAR 1194
                 K EDS    T  +G++R               P I C F+  + Y L CY+YQAR
Sbjct: 1057 KYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQAR 1113

Query: 1195 DLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPP 1254
            +L +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    E PP
Sbjct: 1114 NLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPP 1173

Query: 1255 SIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFE 1307
             +V+EL+  D +G +   GR +  P +        +P + W PL +   +  GE+LAS E
Sbjct: 1174 LVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCE 1233

Query: 1308 LI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI 1366
            LI Q EK     +P   V               P+     +   Y +P++I+P ++R AI
Sbjct: 1234 LILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAI 1273

Query: 1367 EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLP 1424
            EILAWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + V++P
Sbjct: 1274 EILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMP 1328

Query: 1425 REELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSP 1484
             EE Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+     +  LS 
Sbjct: 1329 TEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSE 1383

Query: 1485 G--EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1538
               +D L  +  K          + E  +DWWSK F +  E +    Y  KD+ TLKVY+
Sbjct: 1384 KKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 1442

Query: 1539 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1598
             +LE V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP Q
Sbjct: 1443 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 1499

Query: 1599 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1656
            F     +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+
Sbjct: 1500 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 1559

Query: 1657 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1716
            P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1560 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 1619

Query: 1717 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1774
            C SGP +WRDQ+ PS LL  + ++  +  P++    D V +  K++ ++  E  + P  H
Sbjct: 1620 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 1678

Query: 1775 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1833
             LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  
Sbjct: 1679 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 1738

Query: 1834 NITPRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1884
            NI PR+ +         R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  Q
Sbjct: 1739 NINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQ 1798

Query: 1885 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1944
            KTD+HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WD
Sbjct: 1799 KTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWD 1858

Query: 1945 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTV 1997
            ND FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W         SLF++KTV
Sbjct: 1859 NDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTV 1916

Query: 1998 KGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSF 2057
             GWWPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF
Sbjct: 1917 TGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSF 1976

Query: 2058 LWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2110
             W  SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 1977 TWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 2/103 (1%)

Query: 23  PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82
           P  S+ FR +KKRT+V++ + +PVWNE   W L   PL+  S L V ++D  +  + RF+
Sbjct: 21  PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79

Query: 83  GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSY 124
           G A V L+ +L  PS +    +  LL+   +PT  ++ LQV++
Sbjct: 80  GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH 122



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 270 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 329
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78

Query: 330 LGEFRMDVGTIYREPRHAYLRKWLLL 355
           +G   + +  + ++P      K L L
Sbjct: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104


>gi|35493868 otoferlin isoform b [Homo sapiens]
          Length = 1230

 Score =  720 bits (1858), Expect = 0.0
 Identities = 408/1057 (38%), Positives = 584/1057 (55%), Gaps = 149/1057 (14%)

Query: 1172 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1231
            P +S ++     + LR +MYQAR L A D    SDP+A V F++QSQ T V+  TL PTW
Sbjct: 201  PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260

Query: 1232 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1284
            DQ L+F  +E++GE   + + PP IV+E+YD D+ G  +FMGR   +P ++         
Sbjct: 261  DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320

Query: 1285 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1341
               P+L ++ + RG+  +G+LLA+FEL+Q                    +  +   DLP 
Sbjct: 321  RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360

Query: 1342 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1398
               P       I  VP  I+P L +  +E+L WGLR++K   LA +  P + +EC G+ V
Sbjct: 361  INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420

Query: 1399 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1458
            QS +I N +KNPNF+    + EV LP  EL  PP+ ++V+D R FGR  +VG   + SL 
Sbjct: 421  QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480

Query: 1459 SFLCDPYSAESPSPQGGPDDVSLLSPG---------------EDVLIDID---------- 1493
             F+  P    +PS     + V  + P                 + ++ +D          
Sbjct: 481  RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540

Query: 1494 -----DKEPLIPIQEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1530
                  +EP     +E  +DWWSK+FASI        ++E  G  LE+            
Sbjct: 541  KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600

Query: 1531 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1553
                                                  D LKVY  +LE+   F+   D+
Sbjct: 601  SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658

Query: 1554 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1603
             +TF L RGKT ++    TE+  ++G FKG   +Y  PLPED +           F  + 
Sbjct: 659  LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718

Query: 1604 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1663
            +  P   LVR+Y+VRA  L P D NGK DPYI I +GK  + D++NYI   L PVFGK F
Sbjct: 719  SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778

Query: 1664 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1723
            ++  + P+E  L + +YD+DL+  D+ IGET +DLENR  SK  A CG+ QTY   G N 
Sbjct: 779  DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838

Query: 1724 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1781
            WRD ++PSQ+L   C+  +V  P +    RV   ++ ++   EIE     N    P +E 
Sbjct: 839  WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895

Query: 1782 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1833
            +AL  L+           LVPEHVE+RPL +P +P IEQG+L++WVD+FP  +  PG P 
Sbjct: 896  VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955

Query: 1834 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1892
            +I+PR+ +++ LR IIWNT +V+L DD   TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956  DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015

Query: 1893 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1952
            L GEGNFNWR++FPFDYL AE+   I+KK++ +  D+TE KIPAR+  QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075

Query: 1953 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 2011
            FLG+++LDLNR P+ AKTAK+C+++           VS+F+QK VKGWWP +A  E ++ 
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134

Query: 2012 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2071
             L GK+E  L ++   E E+ P G  R+EP+    LE P RPDTSF+WF +P K+ ++ L
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFL 1191

Query: 2072 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2108
            W  +RW ++  ++L +LLL LA+F+Y+ P Y   K++
Sbjct: 1192 WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1228



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)

Query: 746 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 800
           +EL  GC +   L D  +  S+ T LD+   +     L  + + A  L+  +    +   
Sbjct: 18  EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77

Query: 801 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 860
           L   +++L +LR LA+EPQ+S+PDI IWM+  +KRVAY RVP+  +LFS       GK+C
Sbjct: 78  LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136

Query: 861 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 899
            K++T+FLK P ++  G A   VQ +V+  LW GLS   KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 440 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
           F ++   L DPF  V F  +  C+++L +T  P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262


>gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
          Length = 802

 Score =  714 bits (1842), Expect = 0.0
 Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)

Query: 1385 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1442
            SSP L+VE G +++++  IR+ + NPNF      L + V++P EE Y  P+ VKV+DN  
Sbjct: 5    SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64

Query: 1443 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1496
            FG++ V GQ  I  L+ + CDP++ +   P+     +  LS    +D L  +  K     
Sbjct: 65   FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119

Query: 1497 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1556
                 + E  +DWWSK F +  E +    Y  KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 120  SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178

Query: 1557 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1614
            FKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP QF     +   PQ CLVR+
Sbjct: 179  FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235

Query: 1615 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1674
            Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 236  YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295

Query: 1675 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1734
            L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 296  LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355

Query: 1735 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1791
              + ++  +  P++    D V +  K++ ++  E  + P  H LGP +ERLAL++L  QG
Sbjct: 356  ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414

Query: 1792 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1851
            LVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  NI PR+ +R+ LRCIIW 
Sbjct: 415  LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474

Query: 1852 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1911
            T +V L D +L+ EK SDIY+KGW+ G E+  QKTD+HY SL GE +FNWRFIF  DYL 
Sbjct: 475  TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534

Query: 1912 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1971
            AE+ C  ++KD  W LD T  K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 535  AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594

Query: 1972 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2024
            K+CS+  +D    P+W         SLF++KTV GWWPC   +G K  L+GK++M+LEI+
Sbjct: 595  KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652

Query: 2025 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2084
            +E E   +PAG+G+ EPN  P L  P R +TSF W  SP +   +I W+R+R+ +I F++
Sbjct: 653  SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712

Query: 2085 LFILLLFLAIFIYAFPNYAAMKLVKP 2110
            + I+ L L  FIY+ P+Y AM  +KP
Sbjct: 713  ISIIALMLFNFIYSAPHYLAMSWIKP 738


>gi|35493853 otoferlin isoform c [Homo sapiens]
          Length = 1307

 Score =  712 bits (1839), Expect = 0.0
 Identities = 410/1077 (38%), Positives = 584/1077 (54%), Gaps = 169/1077 (15%)

Query: 1172 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1231
            P +S ++     + LR +MYQAR L A D    SDP+A V F++QSQ T V+  TL PTW
Sbjct: 258  PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 317

Query: 1232 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1284
            DQ L+F  +E++GE   + + PP IV+E+YD D+ G  +FMGR   +P ++         
Sbjct: 318  DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 377

Query: 1285 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1341
               P+L ++ + RG+  +G+LLA+FEL+Q                    +  +   DLP 
Sbjct: 378  RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 417

Query: 1342 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1398
               P       I  VP  I+P L +  +E+L WGLR++K   LA +  P + +EC G+ V
Sbjct: 418  INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 477

Query: 1399 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1458
            QS +I N +KNPNF+    + EV LP  EL  PP+ ++V+D R FGR  +VG   + SL 
Sbjct: 478  QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 537

Query: 1459 SFLCDPYSAESPS--------------PQGGPDDVSL---------------------LS 1483
             F+  P    +PS                GG    S                      L 
Sbjct: 538  RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLD 597

Query: 1484 PGEDVLIDID---------------DKEPLIPIQEEEFIDWWSKFFASIG-------ERE 1521
               + ++ +D                +EP     +E  +DWWSK+FASI        ++E
Sbjct: 598  ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 657

Query: 1522 KCGSYLEKD------------------------------------------------FDT 1533
              G  LE+                                                  D 
Sbjct: 658  PSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE 717

Query: 1534 LKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLP 1587
            LKVY  +LE+   F+   D+ +TF L RGKT ++    TE+  ++G FKG   +Y  PLP
Sbjct: 718  LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 775

Query: 1588 EDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKS 1643
            ED +           F  + +  P   LVR+Y+VRA  L P D NGK DPYI I +GK  
Sbjct: 776  EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 835

Query: 1644 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1703
            + D++NYI   L PVFGK F++  + P+E  L + +YD+DL+  D+ IGET +DLENR  
Sbjct: 836  IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 895

Query: 1704 SKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS- 1761
            SK  A CG+ QTY   G N WRD ++PSQ+L   C+  +V  P +    RV   ++ ++ 
Sbjct: 896  SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 955

Query: 1762 IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQG 1813
              EIE     N    P +E +AL  L+           LVPEHVE+RPL +P +P IEQG
Sbjct: 956  PSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQG 1012

Query: 1814 KLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYV 1872
            +L++WVD+FP  +  PG P +I+PR+ +++ LR IIWNT +V+L DD   TGEK SDI+V
Sbjct: 1013 RLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFV 1072

Query: 1873 KGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTES 1932
            +GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+   I+KK++ +  D+TE 
Sbjct: 1073 RGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEY 1132

Query: 1933 KIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLF 1992
            KIPAR+  QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++           VS+F
Sbjct: 1133 KIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIF 1191

Query: 1993 EQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2051
            +QK VKGWWP +A  E ++  L GK+E  L ++   E E+ P G  R+EP+    LE P 
Sbjct: 1192 KQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPN 1248

Query: 2052 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2108
            RPDTSF+WF +P K+ ++ LW  +RW ++  ++L +LLL LA+F+Y+ P Y   K++
Sbjct: 1249 RPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1305



 Score = 91.3 bits (225), Expect = 9e-18
 Identities = 71/211 (33%), Positives = 110/211 (52%), Gaps = 21/211 (9%)

Query: 697 WEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ-- 754
           W  I+H  ++Q          E GL  +   +K + S  +    +  + +EL  GC +  
Sbjct: 38  WPSITHTPDSQ----------EEGLNDIQEMIKTEKSYPE--RRLRGVLEELSCGCCRFL 85

Query: 755 PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAALEQAEDWLLRL 811
            L D  +  S+ T LD+   +     L  + + A  L+  +    +   L   +++L +L
Sbjct: 86  SLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKL 145

Query: 812 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 871
           R LA+EPQ+S+PDI IWM+  +KRVAY RVP+  +LFS       GK+C K++T+FLK P
Sbjct: 146 RFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLP 204

Query: 872 MEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 899
            ++  G A   VQ +V+  LW GLS   KEF
Sbjct: 205 GKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 235



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 440 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
           F ++   L DPF  V F  +  C+++L +T  P W+Q
Sbjct: 283 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 319


>gi|35493860 otoferlin isoform d [Homo sapiens]
          Length = 1230

 Score =  712 bits (1839), Expect = 0.0
 Identities = 406/1057 (38%), Positives = 583/1057 (55%), Gaps = 149/1057 (14%)

Query: 1172 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1231
            P +S ++     + LR +MYQAR L A D    SDP+A V F++QSQ T V+  TL PTW
Sbjct: 201  PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260

Query: 1232 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1284
            DQ L+F  +E++GE   + + PP IV+E+YD D+ G  +FMGR   +P ++         
Sbjct: 261  DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320

Query: 1285 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1341
               P+L ++ + RG+  +G+LLA+FEL+Q                    +  +   DLP 
Sbjct: 321  RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360

Query: 1342 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1398
               P       I  VP  I+P L +  +E+L WGLR++K   LA +  P + +EC G+ V
Sbjct: 361  INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420

Query: 1399 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1458
            QS +I N +KNPNF+    + EV LP  EL  PP+ ++V+D R FGR  +VG   + SL 
Sbjct: 421  QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480

Query: 1459 SFLCDPYSAESPSPQGGPDDVSLLSPG---------------EDVLIDID---------- 1493
             F+  P    +PS     + V  + P                 + ++ +D          
Sbjct: 481  RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540

Query: 1494 -----DKEPLIPIQEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1530
                  +EP     +E  +DWWSK+FASI        ++E  G  LE+            
Sbjct: 541  KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600

Query: 1531 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1553
                                                  D LKVY  +LE+   F+   D+
Sbjct: 601  SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658

Query: 1554 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1603
             +TF L RGKT ++    TE+  ++G FKG   +Y  PLPED +           F  + 
Sbjct: 659  LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718

Query: 1604 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1663
            +  P   LVR+Y+VRA  L P D NGK DPYI I +GK  + D++NYI   L PVFGK F
Sbjct: 719  SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778

Query: 1664 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1723
            ++  + P+E  L + +YD+DL+  D+ IGET +DLENR  SK  A CG+ QTY   G N 
Sbjct: 779  DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838

Query: 1724 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1781
            WRD ++PSQ+L   C+  +V  P +    RV   ++ ++   EIE     N    P +E 
Sbjct: 839  WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895

Query: 1782 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1833
            +AL  L+           LVPEHVE+RPL +P +P IEQG+L++WVD+FP  +  PG P 
Sbjct: 896  VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955

Query: 1834 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1892
            +I+PR+ +++ LR IIWNT +V+L DD   TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956  DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015

Query: 1893 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1952
            L GEGNFNWR++FPFDYL AE+   I+KK++ +  D+TE KIPAR+  QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075

Query: 1953 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 2011
            FLG+++LDLNR P+ AKTAK+C+++           VS+F+QK VKGWWP +A  E ++ 
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134

Query: 2012 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2071
             L GK+E  L ++   E E+ P G  R+EP+    LE P RPDT+F+WF +P K++K+++
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTAFVWFLNPLKSIKYLI 1191

Query: 2072 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2108
              R++W II  ++  + LL L +F+Y+ P Y   KL+
Sbjct: 1192 CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVKKLL 1228



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)

Query: 746 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 800
           +EL  GC +   L D  +  S+ T LD+   +     L  + + A  L+  +    +   
Sbjct: 18  EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77

Query: 801 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 860
           L   +++L +LR LA+EPQ+S+PDI IWM+  +KRVAY RVP+  +LFS       GK+C
Sbjct: 78  LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136

Query: 861 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 899
            K++T+FLK P ++  G A   VQ +V+  LW GLS   KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 440 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
           F ++   L DPF  V F  +  C+++L +T  P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262


>gi|34740331 otoferlin isoform a [Homo sapiens]
          Length = 1997

 Score =  712 bits (1839), Expect = 0.0
 Identities = 410/1077 (38%), Positives = 584/1077 (54%), Gaps = 169/1077 (15%)

Query: 1172 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1231
            P +S ++     + LR +MYQAR L A D    SDP+A V F++QSQ T V+  TL PTW
Sbjct: 948  PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 1007

Query: 1232 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1284
            DQ L+F  +E++GE   + + PP IV+E+YD D+ G  +FMGR   +P ++         
Sbjct: 1008 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 1067

Query: 1285 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1341
               P+L ++ + RG+  +G+LLA+FEL+Q                    +  +   DLP 
Sbjct: 1068 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 1107

Query: 1342 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1398
               P       I  VP  I+P L +  +E+L WGLR++K   LA +  P + +EC G+ V
Sbjct: 1108 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 1167

Query: 1399 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1458
            QS +I N +KNPNF+    + EV LP  EL  PP+ ++V+D R FGR  +VG   + SL 
Sbjct: 1168 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 1227

Query: 1459 SFLCDPYSAESPS--------------PQGGPDDVSL---------------------LS 1483
             F+  P    +PS                GG    S                      L 
Sbjct: 1228 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLD 1287

Query: 1484 PGEDVLIDID---------------DKEPLIPIQEEEFIDWWSKFFASIG-------ERE 1521
               + ++ +D                +EP     +E  +DWWSK+FASI        ++E
Sbjct: 1288 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 1347

Query: 1522 KCGSYLEKD------------------------------------------------FDT 1533
              G  LE+                                                  D 
Sbjct: 1348 PSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE 1407

Query: 1534 LKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLP 1587
            LKVY  +LE+   F+   D+ +TF L RGKT ++    TE+  ++G FKG   +Y  PLP
Sbjct: 1408 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 1465

Query: 1588 EDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKS 1643
            ED +           F  + +  P   LVR+Y+VRA  L P D NGK DPYI I +GK  
Sbjct: 1466 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 1525

Query: 1644 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1703
            + D++NYI   L PVFGK F++  + P+E  L + +YD+DL+  D+ IGET +DLENR  
Sbjct: 1526 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 1585

Query: 1704 SKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS- 1761
            SK  A CG+ QTY   G N WRD ++PSQ+L   C+  +V  P +    RV   ++ ++ 
Sbjct: 1586 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 1645

Query: 1762 IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQG 1813
              EIE     N    P +E +AL  L+           LVPEHVE+RPL +P +P IEQG
Sbjct: 1646 PSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQG 1702

Query: 1814 KLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYV 1872
            +L++WVD+FP  +  PG P +I+PR+ +++ LR IIWNT +V+L DD   TGEK SDI+V
Sbjct: 1703 RLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFV 1762

Query: 1873 KGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTES 1932
            +GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+   I+KK++ +  D+TE 
Sbjct: 1763 RGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEY 1822

Query: 1933 KIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLF 1992
            KIPAR+  QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++           VS+F
Sbjct: 1823 KIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIF 1881

Query: 1993 EQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2051
            +QK VKGWWP +A  E ++  L GK+E  L ++   E E+ P G  R+EP+    LE P 
Sbjct: 1882 KQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPN 1938

Query: 2052 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2108
            RPDTSF+WF +P K+ ++ LW  +RW ++  ++L +LLL LA+F+Y+ P Y   K++
Sbjct: 1939 RPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1995



 Score =  396 bits (1017), Expect = e-109
 Identities = 299/958 (31%), Positives = 475/958 (49%), Gaps = 126/958 (13%)

Query: 20  RSDPVASLTFRGVKKRTKVIKNSVNPV-WNEGFEWDLKGIPLDQGSELHVVVKDHETMGR 78
           R D +A +TFRG    ++V++N  +   ++E F W +    +D+   L + V ++  +  
Sbjct: 16  RGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVAS-SIDRNEMLEIQVFNYSKVFS 74

Query: 79  NRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPT 138
           N+ +G  ++ L++V+    +  +    L+D        SL ++V Y    G V  +    
Sbjct: 75  NKLIGTFRMVLQKVVEESHVEVTDT--LIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGD 132

Query: 139 PL------EPSPTLPDLDVVAGGGQS----------RAETWSLLSDSTMDTRYSGKKWPA 182
            L      E      + D +  G +           R    S+ S   +    S K+ P 
Sbjct: 133 FLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQ 192

Query: 183 PTDTGGEEDTEDQG----LTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSA 238
             D     + ED        GD  +P         A TT              +  KRS 
Sbjct: 193 RPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTT-------------NVSNKRSK 239

Query: 239 PTSRKLLS-DKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNE 296
           P  +   S  +P D+Q+ + VIE RQL G+N+ PVV V      K T + +  N P +NE
Sbjct: 240 PDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNE 299

Query: 297 TLFFNLFDSPGELFDEPIFITVVDSRSL-RTDALLGEFRMDVGTIYREPRHAYLRKWLLL 355
              F+   SP  +FD+ I I+V+ S++L R+  L+G F+MDVGT+Y +P H +  KW +L
Sbjct: 300 YFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAIL 359

Query: 356 SDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGV--ALRGAHF 413
           SDPDD S+G +GY+K  + V+G GD      K    D++DIE NLL P GV    + A F
Sbjct: 360 SDPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARF 419

Query: 414 CLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQ 473
            +K++RAE LP+M+ ++M NVK+ F  E+  K+LVDP+V+V FAG+   + + + +  P 
Sbjct: 420 YVKIYRAEGLPRMNTSLMANVKKAFIGEN--KDLVDPYVQVFFAGQKGKTSVQKSSYEPL 477

Query: 474 WNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEEEPAGAV 532
           WN+ +    +FP +C++M+++I D D++  ND+ + T ++ + KIS  G +         
Sbjct: 478 WNEQVVFTDLFPPLCKRMKVQIRDSDKV--NDVAIGTHFIDLRKISNDGDK--------- 526

Query: 533 KPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSL 592
                       GFLPT GP ++N+YGS R +T   D + +LN G GEGV++R RLLL L
Sbjct: 527 ------------GFLPTLGPAWVNMYGSTRNYT-LLDEHQDLNEGLGEGVSFRARLLLGL 573

Query: 593 ETKLVEHSEQKVEDLPADDILRVEKYL--------RRRKYSLFAAFYSATML--QDVDDA 642
             ++V+ S     +L +   ++VE+          +  ++ LF AF  A+M+  ++ D  
Sbjct: 574 AVEIVDTSN---PELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKP 630

Query: 643 IQFEVSIGNYGNKFDMTCLP---------------------------------LASTTQY 669
           I FEV+IGNYGN+ D    P                                   S+T  
Sbjct: 631 ITFEVTIGNYGNEVDGLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPP 690

Query: 670 SRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALK 729
            R      +Y++LP+   KP + + S+W D   R+   N +  IAD+LE GL  +   +K
Sbjct: 691 MRPQVTDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIK 750

Query: 730 AQCSTEDVDSLVAQLTDELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEA 786
            + S    +  +  + +EL  GC +   L D  +  S+ T LD+   +     L  + + 
Sbjct: 751 TEKSYP--ERRLRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQ 808

Query: 787 A--LALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAH 844
           A  L  ++    +   L   +++L +LR LA+EPQ+S+PDI IWM+  +KRVAY RVP+ 
Sbjct: 809 ARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSK 868

Query: 845 QVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 899
            +LFS       GK+C K++T+FLK P ++  G A   VQ +V+  LW GLS   KEF
Sbjct: 869 DLLFS-IVEEETGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 925



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 440  FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
            F ++   L DPF  V F  +  C+++L +T  P W+Q
Sbjct: 973  FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 1009



 Score = 32.3 bits (72), Expect = 5.0
 Identities = 13/35 (37%), Positives = 21/35 (60%)

Query: 1206 DPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1240
            DPY  V F  Q  KT V K++  P W++ ++F ++
Sbjct: 453  DPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDL 487


>gi|119120884 fer-1-like 6 [Homo sapiens]
          Length = 1857

 Score =  709 bits (1830), Expect = 0.0
 Identities = 405/1085 (37%), Positives = 580/1085 (53%), Gaps = 172/1085 (15%)

Query: 1162 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1221
            +S+   G N P  + ++   + + LR +MYQAR L A D +  SDP+A V+FL   Q T 
Sbjct: 804  MSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTK 863

Query: 1222 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL 1281
            ++  TL+PTW+Q L+F ++ + G+   +AE PP +VVELYD D  G  E++G  +  P +
Sbjct: 864  IISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVV 923

Query: 1282 E------RMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1335
            +        PRL + P+  G+   G+LLA FEL+Q     +  +P               
Sbjct: 924  KLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLP--------------- 968

Query: 1336 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1395
                P  PP     IY VP NI+P L +  +E+L WG+R MK  QL ++  P  ++ECGG
Sbjct: 969  ----PVEPPDI-TQIYPVPANIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQALIECGG 1023

Query: 1396 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1455
            Q V+SCVI++ + NPNF I     EV LP  EL  PP+++ V+D R FGR  +VG  TI 
Sbjct: 1024 QGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTIN 1083

Query: 1456 SLESFLC--------------------------------------DP-----YSAESPSP 1472
             L+ FLC                                      DP     Y    P P
Sbjct: 1084 YLKQFLCKLREPLAPITQVDGTQPGHDISDSLTATESSGAHSSSQDPPADHIYVDVEPPP 1143

Query: 1473 QGGPDDVSLLSPGEDVLIDIDDKEPLI-----PIQEE----------------------- 1504
               PD          +L+D+ D  P++     P+ +E                       
Sbjct: 1144 TVVPDSAQAQPA---ILVDVPDSSPMLEPEHTPVAQEPPKDGKPKDPRKPSRRSTKRRKR 1200

Query: 1505 --------EFIDWWSKFFASI-------------------------------GEREKCGS 1525
                      IDWWSK++AS+                               G ++K   
Sbjct: 1201 TIADESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKKDK 1260

Query: 1526 YLEK--------DFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEET---EDPSVI 1574
             L+K        +   L++YD  LE+   F    D+  TF+L+RGK+ E+    +   VI
Sbjct: 1261 MLKKKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDRVI 1318

Query: 1575 GEFKGLFKIYPLPEDPAIPMPPRQFHQ--LAAQGPQECLVRIYIVRAFGLQPKDPNGKCD 1632
            G+FKG F IY  P+D +     +   Q  +    P   L+R+YIV AF L P DP+GK D
Sbjct: 1319 GKFKGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSD 1378

Query: 1633 PYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIG 1692
            PYI I +GK  + D+D YIP  L PVFG+ FE+  T P E  L I +YD+D++  D+ IG
Sbjct: 1379 PYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIG 1438

Query: 1693 ETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDR 1752
            ET +DLENR  SK  A CGL   Y + G N WRD  +P+++L   C+ +++  P +   +
Sbjct: 1439 ETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHPGK 1498

Query: 1753 VMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYS 1804
            +   ++ +S + I      +  +   E  LAL VL            LVPEH+E+RPLY 
Sbjct: 1499 IQIGNQVFSGKTIFTEEDTDETVESYEH-LALKVLHSWEDIPEVGCRLVPEHIETRPLYH 1557

Query: 1805 PLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSL-T 1863
              +P +EQG+LQMWVD+FPK + +PGPP +I+PRR + + LR  IWNT DVIL+D ++ T
Sbjct: 1558 KDKPGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFT 1617

Query: 1864 GEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDA 1923
            G+K SDIYVKGW+ G E+ KQ+TDVHY SL GEGNFNWRF+FPF YLPAE+   I K++ 
Sbjct: 1618 GQKSSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKREN 1677

Query: 1924 FWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAF 1983
             + L+K E K PA +V Q+WD ++ S DDFLG+L+++LN  P+ AK+AK C L + ++A 
Sbjct: 1678 IFSLEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENA- 1736

Query: 1984 HPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNM 2043
              E  +S+F+QK V+GWWP      + K L GK+E    +V   E E+ P G+ R EP  
Sbjct: 1737 SEETKISIFQQKRVRGWWPF----SKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPE- 1791

Query: 2044 NPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYA 2103
               L  P RPDTSF WF SP+K + +++W+ ++  II+  IL IL++FL +FIY  P   
Sbjct: 1792 --PLAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAI 1849

Query: 2104 AMKLV 2108
            + ++V
Sbjct: 1850 SRRIV 1854



 Score =  343 bits (879), Expect = 1e-93
 Identities = 235/738 (31%), Positives = 373/738 (50%), Gaps = 126/738 (17%)

Query: 248 KPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSP 306
           + Q++QI + + E RQL G NI PVV +    + K++ + +G NSP +NE   F+     
Sbjct: 79  RSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQ 138

Query: 307 GELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGAR 366
             LFD+ I I+V   + + +  L+G F++D+GT+Y +P H +  KW LL+DP D   G +
Sbjct: 139 VHLFDKIIKISVFHHKLIGS-VLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTK 197

Query: 367 GYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALR--GAHFCLKVFRAEDLP 424
           GYLK  + V+G GD      K  S+ +E IE NLL P G  L    A F +++++AE LP
Sbjct: 198 GYLKCDISVMGKGDVLKTSPK-TSDTEEPIEKNLLIPNGFPLERPWARFYVRLYKAEGLP 256

Query: 425 QMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMF 484
           +M+ ++M NV +   F  + K+LVDPFVEVSFAG+M  + + +  A+P W++ +    MF
Sbjct: 257 KMNSSIMANVTK--AFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMF 314

Query: 485 PSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLDDY 543
           P +C +++I++  WD  + ND+ +AT ++ + KIS                   ++ D  
Sbjct: 315 PPLCRRVKIQV--WDEGSMNDVALATHFIDLKKIS-------------------NEQDGD 353

Query: 544 LGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ- 602
            GFLPTFGP +INLYGSPR  +   D Y E+N G GEGV++RGR+L+ +  +++    Q 
Sbjct: 354 KGFLPTFGPAWINLYGSPRNHS-LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQE 412

Query: 603 -------KVEDLPADD------------------------------ILRVEKY------- 618
                  K   LP+ D                               + VE +       
Sbjct: 413 SKFSKALKELKLPSKDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIV 472

Query: 619 -LRRRKYSLFAAFYSATMLQDV--DDAIQFEVSIGNYGNKFD------------------ 657
             +  ++ LF AF+ ATM+     D  I FEVSIGN+GN  D                  
Sbjct: 473 PEKNEEFLLFGAFFEATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDL 532

Query: 658 -------------MTCLPLASTTQYSRAVF--DGCHYYYLPWGNVKPVVVLSSYWEDISH 702
                           +P+ASTT   + +      +Y YLP+   KP V   S W D + 
Sbjct: 533 LPLLHEGQGDVAHDVPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTF 592

Query: 703 RIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHET 762
           R+   N L  +AD LE  +E+V   +K   S E  +  +  +  + I+  S  + +  + 
Sbjct: 593 RLHWSNMLEKMADFLEESIEEVRELIK--ISQEAPEEKMKTVLSDFISRSSAFISEAEKK 650

Query: 763 P---SATHLDQYLYQLRTHHLSQITEAALAL------KLGHSELPAALEQAEDWLLRLRA 813
           P   + T LD+    L    L  + + A  +      KL   E+   + +A++++ ++R 
Sbjct: 651 PKMLNQTTLDKKRLTLCWQELEAMCKEAKGIIQQQKKKLSVDEM---IHEAQNFVEKIRF 707

Query: 814 LAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPME 873
           L +EPQ+++PD+ IWML  ++RVAY R+ +  +L+S   A   GK+CGK++T FLK P +
Sbjct: 708 LVDEPQHTIPDVFIWMLSNNRRVAYARIASKDLLYS-PVAGQMGKHCGKIKTHFLKPPGK 766

Query: 874 KVPGARMPVQIRVKLWFG 891
           +  G  +  ++ V LW G
Sbjct: 767 RPAGWSVQAKVDVYLWLG 784



 Score = 45.4 bits (106), Expect = 6e-04
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 5/86 (5%)

Query: 6    LVRASNLPSAKKDRRSDP--VASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQG 63
            +V A NL  A  D +SDP  V  L    +K R K I   +NPV+   FE         + 
Sbjct: 1362 IVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQAT---FPKE 1418

Query: 64   SELHVVVKDHETMGRNRFLGEAKVPL 89
            S L +++ DH+ +G +  +GE K+ L
Sbjct: 1419 SLLSILIYDHDMIGTDDLIGETKIDL 1444



 Score = 35.8 bits (81), Expect = 0.46
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 1200 DKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1240
            D     DP+  VSF  Q  +T V KN  +P W + +IF E+
Sbjct: 273  DSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEM 313



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 6   LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNE 49
           + +A  L +A  +  SDP A +TF    + TK+I  +++P WN+
Sbjct: 832 MYQARGLIAADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQ 875



 Score = 33.5 bits (75), Expect = 2.3
 Identities = 13/35 (37%), Positives = 21/35 (60%)

Query: 442 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
           ++   L DPF +V+F      +KI+ +T +P WNQ
Sbjct: 841 ADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQ 875


>gi|4759026 RAS protein activator like 1 [Homo sapiens]
          Length = 804

 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 13/127 (10%)

Query: 1186 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1245
            LRC++  ARDLA  D    SDP+A V +  QS +T  +K T  P WD+ L         E
Sbjct: 135  LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVL---------E 185

Query: 1246 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-SLERMPRLAWF---PLTRGSQPSGE 1301
               +   P  + VEL+D D  G ++F+G     P +L++ P   WF   P  R  + SG 
Sbjct: 186  LREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAEEDSGG 245

Query: 1302 LLASFEL 1308
             L +  +
Sbjct: 246  NLGALRV 252



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 13/167 (7%)

Query: 1526 YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP 1585
            +L  DF  L  Y    + V    G  D      L R   +  T DP  I  +  L ++ P
Sbjct: 60   HLPLDFHQLAFYVLDEDTV----GHDDIIGKISLSR---EAITADPRGIDSWINLSRVDP 112

Query: 1586 LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS 1645
               D  +        Q+   G   CL R +++ A  L P+D +G  DP+ ++  G +S+ 
Sbjct: 113  ---DAEVQGEICLSVQMLEDGQGRCL-RCHVLHARDLAPRDISGTSDPFARVFWGSQSL- 167

Query: 1646 DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIG 1692
             + + I  T  P + ++ EL         L++ L+D+D++ K++ +G
Sbjct: 168  -ETSTIKKTRFPHWDEVLELREMPGAPSPLRVELWDWDMVGKNDFLG 213



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 59/268 (22%), Positives = 100/268 (37%), Gaps = 64/268 (23%)

Query: 254 IRVQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPG 307
           + V+V+EGR LP  ++        +VKV      +   + +   P + E    +L     
Sbjct: 7   LNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHL----- 61

Query: 308 ELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLS--DPDDFSAGA 365
            L    +   V+D  ++  D ++G+  +    I  +PR   +  W+ LS  DPD   A  
Sbjct: 62  PLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRG--IDSWINLSRVDPD---AEV 116

Query: 366 RGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQ 425
           +G +  S+ +L                 ED +   LR              V  A DL  
Sbjct: 117 QGEICLSVQML-----------------EDGQGRCLR------------CHVLHARDLAP 147

Query: 426 MDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFP 485
            D +                   DPF  V +  + L +  ++KT  P W++ + L  M P
Sbjct: 148 RDIS----------------GTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREM-P 190

Query: 486 SMCEKMRIRIIDWDRLTHNDIVATTYLS 513
                +R+ + DWD +  ND +     S
Sbjct: 191 GAPSPLRVELWDWDMVGKNDFLGMVEFS 218



 Score = 35.0 bits (79), Expect = 0.78
 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 5/83 (6%)

Query: 2   LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEW-DLKGIPL 60
           L C ++ A +L        SDP A + +      T  IK +  P W+E  E  ++ G P 
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAP- 193

Query: 61  DQGSELHVVVKDHETMGRNRFLG 83
              S L V + D + +G+N FLG
Sbjct: 194 ---SPLRVELWDWDMVGKNDFLG 213


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)

Query: 1159 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1203
            S SVS    G ++PT               +   +D GN   L  ++ QAR+L   D + 
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726

Query: 1204 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1249
            +SDP+  V  L    + +VV+N              +LNP W+QT+I+  I +       
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780

Query: 1250 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1303
              +  ++ V ++D+D + +++F+G  +   S    L+  PR  W+PL   ++    G+  
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838

Query: 1304 ASFELIQREKPAI 1316
            +S    Q  KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)

Query: 1614 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1661
            I+I++A  L P+D NG  DP++K+ +  G+  V    N          ++  +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770

Query: 1662 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1700
                  ++     +K L++T++DYD  S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812



 Score = 41.2 bits (95), Expect = 0.011
 Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 21/142 (14%)

Query: 33   KKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKVPLR 90
            K+RTK ++ S+NP WN+   +  K I ++Q     L V V D++    N FLGE  + L 
Sbjct: 4754 KRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDL- 4810

Query: 91   EVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPPPTP 139
                  S S   N P     K+ T     G S   Q S  +P P  +      +FP P+ 
Sbjct: 4811 -----SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSK 4865

Query: 140  LEPSPTLPDLDVVAGGGQSRAE 161
                PT+       G  +S +E
Sbjct: 4866 DMQVPTIEKSHSSPGSSKSSSE 4887



 Score = 36.6 bits (83), Expect = 0.27
 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)

Query: 463  SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 518
            +K ++K+ NP+WNQ +   ++     +K  + + + D+DR + ND +    + +S  S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814



 Score = 34.7 bits (78), Expect = 1.0
 Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 35/211 (16%)

Query: 110  KKQPTGASLVLQVSYTPLPGAVPLFP-PPTPLEPSPTLPDLDVVAGGG---QSRAETWSL 165
            K++P  A    Q   +P P A P+    PTP  P PT              Q ++  +SL
Sbjct: 852  KEEPKKA----QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907

Query: 166  LSDSTMDTRYSGKKWPAPTDTG------GEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPR 219
               S  D   S    P  T TG          ++   L     +P      GPGAP    
Sbjct: 908  NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967

Query: 220  KLPSRPP------------PHYPG----IKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQ 263
              PS+PP            P  P     +K++  AP + KL     Q   ++    E + 
Sbjct: 968  PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP 1027

Query: 264  LPGVNIKPVVKVTAAGQ--TKRTRIHKGNSP 292
             P   IK    +TA  Q     T++ K   P
Sbjct: 1028 PP---IKDSKSLTAEPQKAVLPTKLEKSPKP 1055


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)

Query: 1159 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1203
            S SVS    G ++PT               +   +D GN   L  ++ QAR+L   D + 
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726

Query: 1204 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1249
            +SDP+  V  L    + +VV+N              +LNP W+QT+I+  I +       
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780

Query: 1250 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1303
              +  ++ V ++D+D + +++F+G  +   S    L+  PR  W+PL   ++    G+  
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838

Query: 1304 ASFELIQREKPAI 1316
            +S    Q  KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)

Query: 1614 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1661
            I+I++A  L P+D NG  DP++K+ +  G+  V    N          ++  +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770

Query: 1662 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1700
                  ++     +K L++T++DYD  S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 57/211 (27%), Positives = 81/211 (38%), Gaps = 39/211 (18%)

Query: 33   KKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKVPLR 90
            K+RTK ++ S+NP WN+   +  K I ++Q     L V V D++    N FLGE  + L 
Sbjct: 4754 KRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDL- 4810

Query: 91   EVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPPPTP 139
                  S S   N P     K+ T     G S   Q S  +P P  +      +FP P+ 
Sbjct: 4811 -----SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSK 4865

Query: 140  LEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWPAPTDTGGEEDTEDQGLTG 199
                PT+          +S +   S  S S    R  G        +  +   ED G   
Sbjct: 4866 DMQVPTIE---------KSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAI 4916

Query: 200  DEAEPFLDQSGGPGAPTTPRKLPSRPPPHYP 230
              AE  + Q          R  P++PP H P
Sbjct: 4917 AAAEAAVQQL---------RIQPTKPPNHRP 4938



 Score = 36.6 bits (83), Expect = 0.27
 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)

Query: 463  SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 518
            +K ++K+ NP+WNQ +   ++     +K  + + + D+DR + ND +    + +S  S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814



 Score = 34.7 bits (78), Expect = 1.0
 Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 35/211 (16%)

Query: 110  KKQPTGASLVLQVSYTPLPGAVPLFP-PPTPLEPSPTLPDLDVVAGGG---QSRAETWSL 165
            K++P  A    Q   +P P A P+    PTP  P PT              Q ++  +SL
Sbjct: 852  KEEPKKA----QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907

Query: 166  LSDSTMDTRYSGKKWPAPTDTG------GEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPR 219
               S  D   S    P  T TG          ++   L     +P      GPGAP    
Sbjct: 908  NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967

Query: 220  KLPSRPP------------PHYPG----IKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQ 263
              PS+PP            P  P     +K++  AP + KL     Q   ++    E + 
Sbjct: 968  PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP 1027

Query: 264  LPGVNIKPVVKVTAAGQ--TKRTRIHKGNSP 292
             P   IK    +TA  Q     T++ K   P
Sbjct: 1028 PP---IKDSKSLTAEPQKAVLPTKLEKSPKP 1055


>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
            sapiens]
          Length = 778

 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)

Query: 1190 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1249
            + + RDL AMD +  SDPY      HQ  K+ ++  TLNP W +   F+  E        
Sbjct: 255  LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 306

Query: 1250 AEQPPSIVVELYDHDTYGADEFMGRC 1275
             E+   I +  +D D    D+F+GRC
Sbjct: 307  -ERGGVIDITAWDKDAGKRDDFIGRC 331



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 1611 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1670
            +V I ++    L+  D NG  DPY+K  +G +    +   +P TL P + + F+      
Sbjct: 250  IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 307

Query: 1671 LEKDLKITLYDYDLLSKDEKIGETVVDL 1698
                + IT +D D   +D+ IG   VDL
Sbjct: 308  RGGVIDITAWDKDAGKRDDFIGRCQVDL 335



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%)

Query: 6   LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
           ++RA  L +A    +SDP   +     +  T  +  ++NP WN+ F +++K    D  S 
Sbjct: 411 VIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----DIHSV 466

Query: 66  LHVVVKDHETMGRNRFLGEAKVPLREV 92
           L V V D +      FLG+  +PL  +
Sbjct: 467 LEVTVYDEDRDRSADFLGKVAIPLLSI 493



 Score = 41.2 bits (95), Expect = 0.011
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)

Query: 1614 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1671
            I + R   L  +D  G  DPY+K  IG K V  +   I   L PV+    E  C L   L
Sbjct: 44   ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 99

Query: 1672 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1705
             + L I ++DYD   +D+ +G   +DL    L++
Sbjct: 100  REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 133



 Score = 38.9 bits (89), Expect = 0.054
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)

Query: 1595 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1654
            P R FH L   G     +++ ++RA GL   D  GK DP+  + +    +     Y    
Sbjct: 394  PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 447

Query: 1655 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1698
            L P + K+F       +   L++T+YD D     + +G+  + L
Sbjct: 448  LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 490



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 449 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 507
           DP+V+    GK +  SKI+ K  NP W +   +  +   + E + I++ D+D    +D +
Sbjct: 62  DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 119

Query: 508 ATTYLSMSKI 517
            + +L ++++
Sbjct: 120 GSAFLDLTQL 129



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 6   LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
           L+   +L +   +  SDP         K ++K++  ++NP W E F++ L     ++G  
Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGV 311

Query: 66  LHVVVKDHETMGRNRFLGEAKVPL 89
           + +   D +   R+ F+G  +V L
Sbjct: 312 IDITAWDKDAGKRDDFIGRCQVDL 335



 Score = 35.0 bits (79), Expect = 0.78
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)

Query: 1186 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1245
            L+  + +A  L A D    SDP+ +V   +    T  V   LNP W++   F        
Sbjct: 407  LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 458

Query: 1246 PATVAEQPPSIVVELYDHDTYGADEFMGR 1274
               + +    + V +YD D   + +F+G+
Sbjct: 459  --NIKDIHSVLEVTVYDEDRDRSADFLGK 485



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)

Query: 1184 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1240
            Y L   + + + LAA D+   SDPY  V F     +  ++ ++   LNP W++      +
Sbjct: 40   YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 96

Query: 1241 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1273
            +   EP         + ++++D+D    D+FMG
Sbjct: 97   DHLREP---------LYIKVFDYDFGLQDDFMG 120



 Score = 32.0 bits (71), Expect = 6.6
 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 443 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 502
           +   L DP+V+     +   SKI+ KT NPQW +      ++      + I   D D   
Sbjct: 265 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 323

Query: 503 HNDIVATTYLSMSKIS 518
            +D +    + +S +S
Sbjct: 324 RDDFIGRCQVDLSALS 339


>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
            sapiens]
          Length = 999

 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)

Query: 1190 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1249
            + + RDL AMD +  SDPY      HQ  K+ ++  TLNP W +   F+  E        
Sbjct: 476  LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 527

Query: 1250 AEQPPSIVVELYDHDTYGADEFMGRC 1275
             E+   I +  +D D    D+F+GRC
Sbjct: 528  -ERGGVIDITAWDKDAGKRDDFIGRC 552



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 1611 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1670
            +V I ++    L+  D NG  DPY+K  +G +    +   +P TL P + + F+      
Sbjct: 471  IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 528

Query: 1671 LEKDLKITLYDYDLLSKDEKIGETVVDL 1698
                + IT +D D   +D+ IG   VDL
Sbjct: 529  RGGVIDITAWDKDAGKRDDFIGRCQVDL 556



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%)

Query: 6   LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
           ++RA  L +A    +SDP   +     +  T  +  ++NP WN+ F +++K    D  S 
Sbjct: 632 VIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----DIHSV 687

Query: 66  LHVVVKDHETMGRNRFLGEAKVPLREV 92
           L V V D +      FLG+  +PL  +
Sbjct: 688 LEVTVYDEDRDRSADFLGKVAIPLLSI 714



 Score = 41.2 bits (95), Expect = 0.011
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)

Query: 1614 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1671
            I + R   L  +D  G  DPY+K  IG K V  +   I   L PV+    E  C L   L
Sbjct: 265  ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 320

Query: 1672 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1705
             + L I ++DYD   +D+ +G   +DL    L++
Sbjct: 321  REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 354



 Score = 38.9 bits (89), Expect = 0.054
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)

Query: 1595 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1654
            P R FH L   G     +++ ++RA GL   D  GK DP+  + +    +     Y    
Sbjct: 615  PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 668

Query: 1655 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1698
            L P + K+F       +   L++T+YD D     + +G+  + L
Sbjct: 669  LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 711



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 449 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 507
           DP+V+    GK +  SKI+ K  NP W +   +  +   + E + I++ D+D    +D +
Sbjct: 283 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 340

Query: 508 ATTYLSMSKI 517
            + +L ++++
Sbjct: 341 GSAFLDLTQL 350



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 6   LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
           L+   +L +   +  SDP         K ++K++  ++NP W E F++ L     ++G  
Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGV 532

Query: 66  LHVVVKDHETMGRNRFLGEAKVPL 89
           + +   D +   R+ F+G  +V L
Sbjct: 533 IDITAWDKDAGKRDDFIGRCQVDL 556



 Score = 35.0 bits (79), Expect = 0.78
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)

Query: 1186 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1245
            L+  + +A  L A D    SDP+ +V   +    T  V   LNP W++   F        
Sbjct: 628  LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 679

Query: 1246 PATVAEQPPSIVVELYDHDTYGADEFMGR 1274
               + +    + V +YD D   + +F+G+
Sbjct: 680  --NIKDIHSVLEVTVYDEDRDRSADFLGK 706



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)

Query: 1184 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1240
            Y L   + + + LAA D+   SDPY  V F     +  ++ ++   LNP W++      +
Sbjct: 261  YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 317

Query: 1241 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1273
            +   EP         + ++++D+D    D+FMG
Sbjct: 318  DHLREP---------LYIKVFDYDFGLQDDFMG 341



 Score = 32.0 bits (71), Expect = 6.6
 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 443 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 502
           +   L DP+V+     +   SKI+ KT NPQW +      ++      + I   D D   
Sbjct: 486 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 544

Query: 503 HNDIVATTYLSMSKIS 518
            +D +    + +S +S
Sbjct: 545 RDDFIGRCQVDLSALS 560


>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
            isoform 2 [Homo sapiens]
          Length = 731

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)

Query: 1186 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1245
            LRC + +ARDLA  D++  SDP+  V +  ++++T +VK +  P W++T   +E E+  E
Sbjct: 63   LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 118

Query: 1246 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1292
             A  A     + VE +D D    ++F+G+ +      R+ +    WF L
Sbjct: 119  GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 162



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 3/91 (3%)

Query: 2   LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 61
           L C ++ A +L    ++  SDP   + ++G  + T ++K S  P WNE FE++L+   ++
Sbjct: 63  LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 122

Query: 62  QGSELHVVVKDHETMGRNRFLGEAKVPLREV 92
               L V   D + + RN FLG+  + ++ +
Sbjct: 123 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 150



 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 1606 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1665
            G + C +R  ++ A  L PKD NG  DP++++    K  + + + +  +  P + + FE 
Sbjct: 57   GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 114

Query: 1666 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1699
                   + L +  +D+DL+S+++ +G+ V+D++
Sbjct: 115  ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 148



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 31/136 (22%), Positives = 53/136 (38%), Gaps = 18/136 (13%)

Query: 382 APLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFE 441
           A L   DP E+ +  E +L        R       V  A DL   D              
Sbjct: 33  AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-------------- 77

Query: 442 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRL 501
             +    DPFV V + G+   + I++K+  P+WN+         +M E + +   DWD +
Sbjct: 78  --RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-EALCVEAWDWDLV 134

Query: 502 THNDIVATTYLSMSKI 517
           + ND +    + + ++
Sbjct: 135 SRNDFLGKVVIDVQRL 150


>gi|239743307 PREDICTED: similar to calcium-promoted Ras inactivator
            isoform 1 [Homo sapiens]
          Length = 757

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)

Query: 1186 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1245
            LRC + +ARDLA  D++  SDP+  V +  ++++T +VK +  P W++T   +E E+  E
Sbjct: 135  LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 190

Query: 1246 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1292
             A  A     + VE +D D    ++F+G+ +      R+ +    WF L
Sbjct: 191  GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 234



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 3/91 (3%)

Query: 2   LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 61
           L C ++ A +L    ++  SDP   + ++G  + T ++K S  P WNE FE++L+   ++
Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 194

Query: 62  QGSELHVVVKDHETMGRNRFLGEAKVPLREV 92
               L V   D + + RN FLG+  + ++ +
Sbjct: 195 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222



 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 1606 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1665
            G + C +R  ++ A  L PKD NG  DP++++    K  + + + +  +  P + + FE 
Sbjct: 129  GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 186

Query: 1666 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1699
                   + L +  +D+DL+S+++ +G+ V+D++
Sbjct: 187  ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 220



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 53/268 (19%), Positives = 96/268 (35%), Gaps = 60/268 (22%)

Query: 256 VQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGEL 309
           ++++EG+ LP  +I        +VKV      +   + K   P + E    +L  +    
Sbjct: 9   IRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPT---- 64

Query: 310 FDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYL 369
               +   V+D  +L  D ++G+  +   TI   P+                  G  G+ 
Sbjct: 65  -FHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPK------------------GFSGW- 104

Query: 370 KTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDA 429
                       A L   DP E+ +  E +L        R       V  A DL   D  
Sbjct: 105 ------------AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-- 149

Query: 430 VMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCE 489
                         +    DPFV V + G+   + I++K+  P+WN+         +M E
Sbjct: 150 --------------RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-E 194

Query: 490 KMRIRIIDWDRLTHNDIVATTYLSMSKI 517
            + +   DWD ++ ND +    + + ++
Sbjct: 195 ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,800,008
Number of Sequences: 37866
Number of extensions: 4715264
Number of successful extensions: 16889
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 150
Number of HSP's that attempted gapping in prelim test: 15066
Number of HSP's gapped (non-prelim): 1226
length of query: 2112
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1994
effective length of database: 13,779,330
effective search space: 27475984020
effective search space used: 27475984020
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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