Search of human proteins with 195963410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195963410 MEF2 activating motif and SAP domain containing
transcriptional regulator isoform 1 [Homo sapiens]
         (415 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195963410 MEF2 activating motif and SAP domain containing tra...   855   0.0  
gi|32698970 MEF2 activating motif and SAP domain containing tran...   642   0.0  
gi|194097341 period 1 [Homo sapiens]                                   68   1e-11
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    64   2e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    64   2e-10
gi|226423889 myocardin isoform 1 [Homo sapiens]                        63   4e-10
gi|23957692 myocardin isoform 2 [Homo sapiens]                         63   4e-10
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]         63   4e-10
gi|226423891 myocardin isoform 3 [Homo sapiens]                        63   4e-10
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    62   7e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni...    61   2e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    59   8e-09
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              59   8e-09
gi|62955044 F-box protein 42 [Homo sapiens]                            58   1e-08
gi|171543895 ataxin 2 [Homo sapiens]                                   57   3e-08
gi|47132519 Ras association and pleckstrin homology domains 1 is...    57   3e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   55   9e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   55   9e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   55   9e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    55   9e-08
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    55   1e-07
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    55   1e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   1e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    55   2e-07
gi|116284392 mucin 2 precursor [Homo sapiens]                          54   2e-07
gi|55741677 SET domain containing 1A [Homo sapiens]                    54   2e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    54   2e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         54   2e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    54   3e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    54   3e-07

>gi|195963410 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 1 [Homo sapiens]
          Length = 415

 Score =  855 bits (2210), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MTLAASSQRSQIIRSKFRSVLQLRIHRRNQEQISDPDPWISASDPPLAPALPSGTAPFLF 60
           MTLAASSQRSQIIRSKFRSVLQLRIHRRNQEQISDPDPWISASDPPLAPALPSGTAPFLF
Sbjct: 1   MTLAASSQRSQIIRSKFRSVLQLRIHRRNQEQISDPDPWISASDPPLAPALPSGTAPFLF 60

Query: 61  SPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEG 120
           SPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEG
Sbjct: 61  SPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEG 120

Query: 121 SALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSEL 180
           SALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSEL
Sbjct: 121 SALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSEL 180

Query: 181 RQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQG 240
           RQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQG
Sbjct: 181 RQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQG 240

Query: 241 SVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIR 300
           SVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIR
Sbjct: 241 SVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIR 300

Query: 301 RAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTN 360
           RAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTN
Sbjct: 301 RAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTN 360

Query: 361 SSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSSSSRLWDLLEDPW 415
           SSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSSSSRLWDLLEDPW
Sbjct: 361 SSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSSSSRLWDLLEDPW 415


>gi|32698970 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 2 [Homo sapiens]
          Length = 312

 Score =  642 bits (1657), Expect = 0.0
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 104 MPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPH 163
           MPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPH
Sbjct: 1   MPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPH 60

Query: 164 KLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGA 223
           KLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGA
Sbjct: 61  KLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGA 120

Query: 224 PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSG 283
           PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSG
Sbjct: 121 PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSG 180

Query: 284 PGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPD 343
           PGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPD
Sbjct: 181 PGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPD 240

Query: 344 SEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSS 403
           SEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSS
Sbjct: 241 SEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSS 300

Query: 404 SSRLWDLLEDPW 415
           SSRLWDLLEDPW
Sbjct: 301 SSRLWDLLEDPW 312


>gi|194097341 period 1 [Homo sapiens]
          Length = 1290

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 85/286 (29%), Positives = 108/286 (37%), Gaps = 46/286 (16%)

Query: 141  PRMKPSPLTPCPPGVPSPSPPPHK--------LELQTLKLEELTVSELRQQLRLRGLPVS 192
            P   PSP  P P   P P+P  ++        L L T K E+  +S  R   RLRGL  S
Sbjct: 752  PGPAPSP-APSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSS 810

Query: 193  GTK-SMLLER--MRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASH 249
             T  S L ER    G APP  R   R   S A        P+A A         P   SH
Sbjct: 811  STAPSALGERGCHHGPAPPSRRHHCR---SKAKRSRHHQNPRAEA---------PCYVSH 858

Query: 250  RPPLPRAADTPGTAPAPTPTPA---PAAAPALTPSSGP------------GSAALTLEEE 294
              P+P +   P T PA TP PA   P   P  +P  GP             +    L   
Sbjct: 859  PSPVPPSTPWP-TPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTP 917

Query: 295  LQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSS 354
            +   +    L P          Q   + P  P       S   L+PSP     S +F+S 
Sbjct: 918  MVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSR 977

Query: 355  LPSPTNSSSPSPRDPTDSLDWLE--ALSGGPPLGSGPPPPSIFSAD 398
              SP   +        + L   E  A++GGP   +GPPPPS  +A+
Sbjct: 978  CSSPLQLNLLQ----LEELPRAEGAAVAGGPGSSAGPPPPSAEAAE 1019



 Score = 36.6 bits (83), Expect = 0.043
 Identities = 47/168 (27%), Positives = 60/168 (35%), Gaps = 21/168 (12%)

Query: 253 LPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAI---RRAQLLPNRG 309
           LP  A  P  +PAP+PT AP  AP      G   A L+L  + +E     R   L   RG
Sbjct: 747 LPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRG 806

Query: 310 ID------DILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSS 363
           +D        L ++     P PP       S    S    +    +    S PSP   S+
Sbjct: 807 LDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPST 866

Query: 364 PSPRDPTDS----------LDWLEALSGGPPLGSGPP--PPSIFSADL 399
           P P  P  +          L       G  PL   P   PP+ F A L
Sbjct: 867 PWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPL 914



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 41/142 (28%), Positives = 47/142 (33%), Gaps = 18/142 (12%)

Query: 141  PRMKPSPLTPCPPGVPSPS-PPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLL 199
            PR  P PL P P  VP  + P P    +  L L             L   P S     L 
Sbjct: 891  PRGGPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNY----------LFPTPSSYPYGALQ 940

Query: 200  ERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRA--- 256
                G  PP           PA AP P  +P +     R  S           LPRA   
Sbjct: 941  TPAEG--PPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGA 998

Query: 257  --ADTPGTAPAPTPTPAPAAAP 276
              A  PG++  P P  A AA P
Sbjct: 999  AVAGGPGSSAGPPPPSAEAAEP 1020



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 10/14 (71%), Positives = 11/14 (78%)

Query: 151 CPPGVPSPSPPPHK 164
           CP GVPSP PP H+
Sbjct: 21  CPGGVPSPGPPQHR 34


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 97/354 (27%), Positives = 121/354 (34%), Gaps = 56/354 (15%)

Query: 54  GTAPFLFSPGVLLPEPE-YCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGS 112
           G+ P L  PG      + + PP    +   P    R    +P+ N    +  PP P  GS
Sbjct: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRN----RMPPPRPDVGS 178

Query: 113 RADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKL 172
           + D      ++ PP PS      S  PH R  P    P P G   PSP P        + 
Sbjct: 179 KPD------SIPPPVPSTPRPIQSS-PHNRGSP----PVPGGPRQPSPGPTPPPFPGNRG 227

Query: 173 EELTVSELRQQLRLRGLPVSG------TKSMLLERMRGGAPPR--ERPKPRREDSPAGAP 224
             L    +RQ       P S       T S  L+      PP    RP   RE  P   P
Sbjct: 228 TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP 287

Query: 225 WPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGP 284
                P          + +PSA+S  PP             P P P+    P L PSS  
Sbjct: 288 QNNKPPVP-------STPRPSASSQAPP-------------PPPPPSRPGPPPLPPSSSG 327

Query: 285 GSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDS 344
                 L +           LP+ G    L     P +  PP   D PG    L P P  
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP--PPSERPPPPVRDPPGRSGPLPPPPPV 385

Query: 345 EGLSSVFSSSLPS----PTNSSSPSPRD-PTDSLDWLEALSGGPPLGSGPPPPS 393
               S  S +LP+    P+ S   SPR  P   L      +G PP    PPPPS
Sbjct: 386 SRNGST-SRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP----PPPPS 434



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 54/202 (26%), Positives = 70/202 (34%), Gaps = 17/202 (8%)

Query: 36  PDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           P P  +  D P  P  P G  P +    V  P P+   P   P   +P+ S    ++ P 
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP---PVPSTPRPSAS-SQAPPP 309

Query: 96  GNLTYHQYMPPEPRQGSRAD-----PQ--AEGSALGPPGPSLWEGTDSQQPHPRMKPSPL 148
                    PP P   S  D     PQ     S+  PP PS    +    P P  +P P 
Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR-SGPLPPPPSERPPPP 368

Query: 149 TPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSML-LERMRGGAP 207
              PPG   P PPP  +         L  +           P SG +  L  +R   GAP
Sbjct: 369 VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428

Query: 208 PRERP----KPRREDSPAGAPW 225
           P   P    +   +DSP    W
Sbjct: 429 PPPPPSTSIRNGFQDSPCEDEW 450


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 97/354 (27%), Positives = 121/354 (34%), Gaps = 56/354 (15%)

Query: 54  GTAPFLFSPGVLLPEPE-YCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGS 112
           G+ P L  PG      + + PP    +   P    R    +P+ N    +  PP P  GS
Sbjct: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRN----RMPPPRPDVGS 178

Query: 113 RADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKL 172
           + D      ++ PP PS      S  PH R  P    P P G   PSP P        + 
Sbjct: 179 KPD------SIPPPVPSTPRPIQSS-PHNRGSP----PVPGGPRQPSPGPTPPPFPGNRG 227

Query: 173 EELTVSELRQQLRLRGLPVSG------TKSMLLERMRGGAPPR--ERPKPRREDSPAGAP 224
             L    +RQ       P S       T S  L+      PP    RP   RE  P   P
Sbjct: 228 TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP 287

Query: 225 WPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGP 284
                P          + +PSA+S  PP             P P P+    P L PSS  
Sbjct: 288 QNNKPPVP-------STPRPSASSQAPP-------------PPPPPSRPGPPPLPPSSSG 327

Query: 285 GSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDS 344
                 L +           LP+ G    L     P +  PP   D PG    L P P  
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP--PPSERPPPPVRDPPGRSGPLPPPPPV 385

Query: 345 EGLSSVFSSSLPS----PTNSSSPSPRD-PTDSLDWLEALSGGPPLGSGPPPPS 393
               S  S +LP+    P+ S   SPR  P   L      +G PP    PPPPS
Sbjct: 386 SRNGST-SRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP----PPPPS 434



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 54/202 (26%), Positives = 70/202 (34%), Gaps = 17/202 (8%)

Query: 36  PDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           P P  +  D P  P  P G  P +    V  P P+   P   P   +P+ S    ++ P 
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP---PVPSTPRPSAS-SQAPPP 309

Query: 96  GNLTYHQYMPPEPRQGSRAD-----PQ--AEGSALGPPGPSLWEGTDSQQPHPRMKPSPL 148
                    PP P   S  D     PQ     S+  PP PS    +    P P  +P P 
Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR-SGPLPPPPSERPPPP 368

Query: 149 TPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSML-LERMRGGAP 207
              PPG   P PPP  +         L  +           P SG +  L  +R   GAP
Sbjct: 369 VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428

Query: 208 PRERP----KPRREDSPAGAPW 225
           P   P    +   +DSP    W
Sbjct: 429 PPPPPSTSIRNGFQDSPCEDEW 450


>gi|226423889 myocardin isoform 1 [Homo sapiens]
          Length = 986

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 71/275 (25%), Positives = 99/275 (36%), Gaps = 75/275 (27%)

Query: 76  RSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADP------------------- 116
           + PK   PK+ +          L YHQY+PP+ +      P                   
Sbjct: 251 KKPKDPKPKVKK----------LKYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQ 300

Query: 117 ---------QAEGSALGPPGPSLWEGTDSQQPHPRMKPSPL--TPCPP---------GV- 155
                    Q   S LG     L E  +    +P    +PL  TP  P         GV 
Sbjct: 301 ILSQQQQQQQHRFSYLGMHQAQLKEPNEQMVRNPNSSSTPLSNTPLSPVKNSFSGQTGVS 360

Query: 156 ---PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
              P P PP          L++L VSELRQQLR+RGLPVSGTK+ L++R+R        P
Sbjct: 361 SFKPGPLPP---------NLDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPFQDCSGNP 411

Query: 213 KPRREDSPAGA------PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAP 266
            P   D             P  +  +  +A   G     + S  PP+     +P ++   
Sbjct: 412 VPNFGDITTVTFPVTPNTLPNYQSSSSTSALSNGFYHFGSTSSSPPI-----SPASSDLS 466

Query: 267 TPTPAPAAAPALTPSSG--PGSAALTLEEELQEAI 299
                P      +PS G  P    +  EE L  ++
Sbjct: 467 VAGSLPDTFNDASPSFGLHPSPVHVCTEESLMSSL 501



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 22/36 (61%), Positives = 28/36 (77%), Gaps = 2/36 (5%)

Query: 1  MTLAASSQRSQIIRSKFRSVLQLRI-HRRNQEQISD 35
          MTL  S + S +IRSKFRSVLQLR+  RR QEQ+++
Sbjct: 1  MTLLGS-EHSLLIRSKFRSVLQLRLQQRRTQEQLAN 35


>gi|23957692 myocardin isoform 2 [Homo sapiens]
          Length = 938

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 71/275 (25%), Positives = 99/275 (36%), Gaps = 75/275 (27%)

Query: 76  RSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADP------------------- 116
           + PK   PK+ +          L YHQY+PP+ +      P                   
Sbjct: 251 KKPKDPKPKVKK----------LKYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQ 300

Query: 117 ---------QAEGSALGPPGPSLWEGTDSQQPHPRMKPSPL--TPCPP---------GV- 155
                    Q   S LG     L E  +    +P    +PL  TP  P         GV 
Sbjct: 301 ILSQQQQQQQHRFSYLGMHQAQLKEPNEQMVRNPNSSSTPLSNTPLSPVKNSFSGQTGVS 360

Query: 156 ---PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
              P P PP          L++L VSELRQQLR+RGLPVSGTK+ L++R+R        P
Sbjct: 361 SFKPGPLPP---------NLDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPFQDCSGNP 411

Query: 213 KPRREDSPAGA------PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAP 266
            P   D             P  +  +  +A   G     + S  PP+     +P ++   
Sbjct: 412 VPNFGDITTVTFPVTPNTLPNYQSSSSTSALSNGFYHFGSTSSSPPI-----SPASSDLS 466

Query: 267 TPTPAPAAAPALTPSSG--PGSAALTLEEELQEAI 299
                P      +PS G  P    +  EE L  ++
Sbjct: 467 VAGSLPDTFNDASPSFGLHPSPVHVCTEESLMSSL 501



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 22/36 (61%), Positives = 28/36 (77%), Gaps = 2/36 (5%)

Query: 1  MTLAASSQRSQIIRSKFRSVLQLRI-HRRNQEQISD 35
          MTL  S + S +IRSKFRSVLQLR+  RR QEQ+++
Sbjct: 1  MTLLGS-EHSLLIRSKFRSVLQLRLQQRRTQEQLAN 35


>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
          Length = 931

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 77/287 (26%), Positives = 114/287 (39%), Gaps = 59/287 (20%)

Query: 20  VLQLRIHRRNQEQISDPDPWISASDPPLAPALPSGTA-PFLFSPGVLLPEPEYCPPWRSP 78
           V QL + R ++E +   +       P L P+L +GT  P   S   L+ + +       P
Sbjct: 161 VSQLPMGRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQ-------P 213

Query: 79  KKESPKI--SQRWRESKPR-GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTD 135
           K  S K   S++ +E KP+   L YHQY+PP+ +Q   A P     A       L+    
Sbjct: 214 KSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQ 273

Query: 136 --SQQPHPRMKPSPLTPCPP----------GVP-------------SPSPPPHKLELQT- 169
             +QQ         + P PP          G P             S +P P  L  Q  
Sbjct: 274 ILNQQQQQHHNYQAILPAPPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNS 333

Query: 170 -----------LKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRRED 218
                        L+++ V+EL+Q+L+LR LPVSGTK+ L+ER+R             +D
Sbjct: 334 TSLTGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRA-----------YQD 382

Query: 219 SPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPA 265
             +  P     P A +   + G V  +  + R     A    G APA
Sbjct: 383 QISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPA 429



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 105/431 (24%), Positives = 156/431 (36%), Gaps = 74/431 (17%)

Query: 8   QRSQIIRSKFRSVLQLRIHRRNQEQISDPDPW------------ISASDPPLAPALPSGT 55
           Q+ Q++    R  LQL   +R Q+    P P                S  PL PA P   
Sbjct: 543 QKQQLVE---RLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHP--- 596

Query: 56  APFLFSPGVLLPEPEYCPPWR-SPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRA 114
               F+P +  P   +  P   +P   S  + Q   + +P           P P      
Sbjct: 597 ----FNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPE----------PVPA----- 637

Query: 115 DPQAEGSALGPPGPSLWEG-------TDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLEL 167
            PQ     LGP GPSL +G       TDS   H  +  +      PG+ S SP     + 
Sbjct: 638 -PQL---LLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQP 693

Query: 168 QTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAP-WP 226
            +         +L   L+    P+ GT + LL++   G       +P+++++ + +    
Sbjct: 694 GSPAPAPSAQMDLEHPLQ----PLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMD 749

Query: 227 RLKPKALAAARRQGSVK--PSAASHRPPLPRAADTPGTAPAPTPTPA-PAAAPALTPSSG 283
            L    + +       K  PS      P P+       A  P+P+   P AAP   P  G
Sbjct: 750 DLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAP---PPPG 806

Query: 284 PGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPD 343
             S    LE+ L+ +     L           D  EP   +  +      S  +L   P 
Sbjct: 807 SPSLPGRLEDFLESSTGLPLLTSGH-------DGPEPLSLIDDLHSQMLSSTAILDHPPS 859

Query: 344 SEGLSSVFSSSLPSPTNSSSPSPRDP-TDSLDWLEALSGGPPLGSGP---PPPSIFSADL 399
               S +    +P P+++      D   DS+DWLE  SGGP L   P     PS+FS D 
Sbjct: 860 PMDTSELHF--VPEPSSTMGLDLADGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSTDF 917

Query: 400 SDSSSSRL-WD 409
            D    +L WD
Sbjct: 918 LDGHDLQLHWD 928


>gi|226423891 myocardin isoform 3 [Homo sapiens]
          Length = 684

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 71/275 (25%), Positives = 99/275 (36%), Gaps = 75/275 (27%)

Query: 76  RSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADP------------------- 116
           + PK   PK+ +          L YHQY+PP+ +      P                   
Sbjct: 155 KKPKDPKPKVKK----------LKYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQ 204

Query: 117 ---------QAEGSALGPPGPSLWEGTDSQQPHPRMKPSPL--TPCPP---------GV- 155
                    Q   S LG     L E  +    +P    +PL  TP  P         GV 
Sbjct: 205 ILSQQQQQQQHRFSYLGMHQAQLKEPNEQMVRNPNSSSTPLSNTPLSPVKNSFSGQTGVS 264

Query: 156 ---PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
              P P PP          L++L VSELRQQLR+RGLPVSGTK+ L++R+R        P
Sbjct: 265 SFKPGPLPP---------NLDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPFQDCSGNP 315

Query: 213 KPRREDSPAGA------PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAP 266
            P   D             P  +  +  +A   G     + S  PP+     +P ++   
Sbjct: 316 VPNFGDITTVTFPVTPNTLPNYQSSSSTSALSNGFYHFGSTSSSPPI-----SPASSDLS 370

Query: 267 TPTPAPAAAPALTPSSG--PGSAALTLEEELQEAI 299
                P      +PS G  P    +  EE L  ++
Sbjct: 371 VAGSLPDTFNDASPSFGLHPSPVHVCTEESLMSSL 405


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 77/280 (27%), Positives = 110/280 (39%), Gaps = 28/280 (10%)

Query: 43   SDPPLAPALPSGTAPFLFSPGVLLPEPE--YCPPWRSPKKESPKISQ---RWRESKPRGN 97
            S+PPL P  P    P L  PG+ + + +    PP  +P   +P   Q   R +   P G 
Sbjct: 815  SEPPLHPCPPPQAPPTL--PGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGP 872

Query: 98   LTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLW--EGTDSQQPHPRMKPSP-LTPCPPG 154
            L    ++PP     + A      S L  P PS +  +   SQ PH    P P L   P  
Sbjct: 873  LPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEP 932

Query: 155  VPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKP 214
               P PPP   ++ T     L   +   + R   +P      ++L+   GGAP    P+ 
Sbjct: 933  AAPPPPPPRTFQMVTTPFPALPQPKALLE-RFHQVP----SGIILQNKAGGAP--AAPQT 985

Query: 215  RREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRP-PLPRAA-DTPGTAPAPTPTPA- 271
                 P  +P       ++  + +  S  P+A SH P P P AA   P   PA     A 
Sbjct: 986  STSLGPLTSP-----AASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFAS 1040

Query: 272  --PAAAPALTPSSGPGS-AALTLEEELQEAIRRAQLLPNR 308
              P    A   SSGPG  + L  E +L    +   L P++
Sbjct: 1041 NLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSK 1080



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 85/323 (26%), Positives = 116/323 (35%), Gaps = 60/323 (18%)

Query: 116 PQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGV--PSPSPPPHKLELQTLKLE 173
           P    +A G   P L     + QP P+  P+  TP P G+  P    PP     Q     
Sbjct: 605 PATPAAATGEAAPVL-----TVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP 659

Query: 174 ELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP-------------KPRREDSP 220
           + T  +        GL  S  K +L      G PP   P                R   P
Sbjct: 660 QATTPQPSP-----GLASSPEKIVL------GQPPSATPTAILTQDSLQMFLPQERSQQP 708

Query: 221 AGAPWPRLK-PKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPA-AAPAL 278
             A  P L  P ++  +    +  P+ A+   P+ + A     AP    +PAPA   PA 
Sbjct: 709 LSAEGPHLSVPASVIVSAPPPAQDPAPAT---PVAKGAGLGPQAPDSQASPAPAPQIPAA 765

Query: 279 TPSSGPG---SAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSF 335
            P  GPG   S +L  +  L ++       P R              P  P  +  P S 
Sbjct: 766 APLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTR---------PPSRPPSRPQSVSRPPSE 816

Query: 336 DVLSPSPDSEGLSS-----VFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGSGPP 390
             L P P  +   +     V  + L  P  +S+P+P  P      L   S  PP G  PP
Sbjct: 817 PPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS-QPPEGPLPP 875

Query: 391 ----PPSIFSADLSDSS--SSRL 407
               PPS  S+ ++ SS  SSRL
Sbjct: 876 APHLPPSSTSSAVASSSETSSRL 898



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 85/372 (22%), Positives = 116/372 (31%), Gaps = 108/372 (29%)

Query: 42  ASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTYH 101
           A  PP AP  P   AP    P    P+P    P  +   E   + Q    + P   LT  
Sbjct: 644 AQQPPQAPT-PQAAAP----PQATTPQPS---PGLASSPEKIVLGQP-PSATPTAILTQD 694

Query: 102 QYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTP----------C 151
                 P++ S+    AEG  L  P   +        P P   P+P TP           
Sbjct: 695 SLQMFLPQERSQQPLSAEGPHLSVPASVIVSA-----PPPAQDPAPATPVAKGAGLGPQA 749

Query: 152 PPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRER 211
           P    SP+P P                ++     L+G   S + S+  +   G +P    
Sbjct: 750 PDSQASPAPAP----------------QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793

Query: 212 PKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPP-------LPRAADTPGTAP 264
           P P R  S      P  +P++++    +  + P      PP       +      P  A 
Sbjct: 794 PHPTRPPSR-----PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPAS 848

Query: 265 APTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPL 324
            P PT      P L P S P                                   P+ PL
Sbjct: 849 NPAPTAPGPPQPPLRPQSQP-----------------------------------PEGPL 873

Query: 325 PPIPLDFPGSFDVLSPSPDSEGL--SSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGG 382
           PP P         L PS  S  +  SS  SS LP+PT S       P+            
Sbjct: 874 PPAPH--------LPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQG---------- 915

Query: 383 PPLGSGPPPPSI 394
            P  S  PPP++
Sbjct: 916 -PHKSPTPPPTL 926



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 67/253 (26%), Positives = 92/253 (36%), Gaps = 38/253 (15%)

Query: 156 PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPR 215
           P+P+ P     LQ + L    V+ L       GL    T +       G A P    +P 
Sbjct: 572 PAPAGPAATTVLQGVTLPPSAVAMLNTP---DGLVQPATPAAAT----GEAAPVLTVQPA 624

Query: 216 REDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAA 275
            +  PA +      P  L   + Q    P A     P P+AA  P  A  P P+P  A++
Sbjct: 625 PQAPPAVST-----PLPLGLQQPQAQQPPQA-----PTPQAA-APPQATTPQPSPGLASS 673

Query: 276 PALTPSSGPGSA---ALTLEEELQEAI---RRAQLLPNRG------IDDILEDQVEPDDP 323
           P       P SA   A+  ++ LQ  +   R  Q L   G         I+       DP
Sbjct: 674 PEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDP 733

Query: 324 LPPIPLDFPGSFDVLSP-SPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGG 382
            P  P+        L P +PDS+  S   +  +P+      P P   + SL     L   
Sbjct: 734 APATPVAKGAG---LGPQAPDSQA-SPAPAPQIPAAAPLKGPGP-SSSPSLPHQAPLGDS 788

Query: 383 PPLGSGPP--PPS 393
           P L S  P  PPS
Sbjct: 789 PHLPSPHPTRPPS 801



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 54/216 (25%), Positives = 69/216 (31%), Gaps = 23/216 (10%)

Query: 152  PPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRER 211
            PP  P P PPP      T+        E +        P    +    E + G   P   
Sbjct: 1345 PPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGT 1404

Query: 212  PKPR-REDSPAGAPWPRLKPKALAAARRQGSVKPSAASHR-----PPLPRAADTPGTAPA 265
            P  R R  SP  AP P    +A +   R+ +        R     PP P A+   GT   
Sbjct: 1405 PAGRARGGSP--APLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462

Query: 266  PTPTPA-PAAAPALTPSSGPGSAAL--------TLEEELQEA---IRRAQLLPNRGIDDI 313
                P  P A    + S     A+         TL E LQ A   I   Q  P R     
Sbjct: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPS 1522

Query: 314  LEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSS 349
                     P  P PL  P ++    PS  + GL +
Sbjct: 1523 YPHAASAGTPASPPPLHRPEAY---PPSSHNGGLGA 1555


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 88/338 (26%), Positives = 124/338 (36%), Gaps = 33/338 (9%)

Query: 46   PLAP---ALPSGTAPFLFSPGVL-LPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTYH 101
            PL+P    LP    P   +P V+ LP P+  P   +PK ++P +S      K        
Sbjct: 872  PLSPKGVTLPPKETP---TPSVVNLPFPKEGPATPAPK-QAPALSMTSSSPKKARATPAP 927

Query: 102  QYMPPEPR-QGSRADPQAEGSAL--GPPGPS-LWEGTDSQQPHPRMKPSPLTPCPPGVPS 157
            + +P  P  +G+   P A   +   GP  PS  W  T      P  K  P TP P G P+
Sbjct: 928  KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987

Query: 158  P---SPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKP 214
            P   +PP  K    T   +             +G P +          +G + P     P
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP------KGASTPPAATPP 1041

Query: 215  RREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHR-PPLPRAADTPGTAPAPTPTPAPA 273
              + SPA  P P+  P   AA        P+  S +  P P AA  P     P  TP+P 
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA-TPSPK 1100

Query: 274  AA---PALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLD 330
             A   PA TP S  G  A    +            P  G+         P    P  P  
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL------ATPPPKGAPTTPAA 1154

Query: 331  FPGSFDVLSPSPDSEGLSSVFSSSLPSPTNS-SSPSPR 367
             P S      +P  +G  +  +++ PSP    ++PSP+
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 107/411 (26%), Positives = 146/411 (35%), Gaps = 89/411 (21%)

Query: 38   PWISASDPPLAPALP-SGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRG 96
            P I  S P  +P+LP +GT P       +       P   SPK+   + S     +  +G
Sbjct: 728  PEIPKSVP--SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG 785

Query: 97   NLTYHQYMP-------------PEPRQGSRADPQAEGSALGPPGPS----LWEGTDSQQ- 138
             LTY    P             P  ++GS       G+   P  P     L E + S Q 
Sbjct: 786  TLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG 845

Query: 139  --PHPRMKPSPLTPCPPGVPSPSP-PPHKLELQTLKLEEL-TVSELRQQLRLRGLPVSGT 194
                P    SP  P P G P+PS   P   +  TL  +E  T S +       G      
Sbjct: 846  SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905

Query: 195  KSMLLERMRGGAPPRERPKPRRED-----SPAGAPWPRLKPKALAAARRQGSVKPSA--- 246
            K      M   +P + R  P  +      SP GAP P   P A   + + G   PS    
Sbjct: 906  KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP---PAATPPSPKGGPATPSPKWA 962

Query: 247  ----ASHRP--------PLPRAADTPGTAPAPTP-----TPAPAAAP---ALTPSSGPGS 286
                A+  P        P P+ A TP  A  P+P     TP+P  AP   A+TP S  GS
Sbjct: 963  PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022

Query: 287  AALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEG 346
             A T                        +    P    PP P   P +      +P  +G
Sbjct: 1023 PAAT---------------------PFPKGASTPPAATPPSPKGSPAA------TPLPKG 1055

Query: 347  LSSVFSSSLPSPTNS-SSPSPRD-PTDSLDWLEALSGGP----PLGSGPPP 391
              +  +++LPSP    ++PS +  PT       +  GGP    P G+  PP
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 101/404 (25%), Positives = 134/404 (33%), Gaps = 67/404 (16%)

Query: 45   PPLAPALPSGTAPFLFSP--GVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQ 102
            P  AP  P+ T P   SP  G   P P+  P   +    SPK S       P+G  T   
Sbjct: 982  PKGAPTPPAATPP---SPKGGPATPSPKGAPTPPAVTPPSPKGSPA-ATPFPKGASTPPA 1037

Query: 103  YMPPEPRQGSRADPQAEGSAL-----------GPPGPSLWEG-TDSQQPHPRMKPSPLTP 150
              PP P+    A P  +G+             GP  PSL    T      P  K  P TP
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 151  CPPGVPSP------------SPPPHKLELQTLKLEELTVSELRQQLRLRGLPVS------ 192
             P G P P            + PPHK    T      +          +G P +      
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157

Query: 193  GTKSMLLERMRGGAPPRER---PKPR---REDSPAGAPW-PRLKPKA----LAAARRQGS 241
              K  L      GAP       P P+      SP GAP  P   P +    LA    +G+
Sbjct: 1158 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1217

Query: 242  -VKPSAASHRP------PLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEE 294
               P+A    P      P P+ A T   A  P+P   PA  P     + P +   +L+  
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277

Query: 295  LQEAIRRAQLLPNRGIDD--ILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFS 352
            L          P++G  +  ++        P    P   P       PSP      +   
Sbjct: 1278 LATP-------PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP-GTPPP 1329

Query: 353  SSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGS---GPPPPS 393
               P+P   + PSP+          +  GGP   S   GP PP+
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 99/385 (25%), Positives = 132/385 (34%), Gaps = 68/385 (17%)

Query: 38   PWISASDPPLAPALPSG-------TAPFLF--SPGVLLPEPEYCPPWR---SPKKESPKI 85
            P +  S P   PA PS        TA  L   +P  L P+    PP     SPKK +P I
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK-TPAI 1564

Query: 86   SQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQ----PHP 141
                                P P++        E S+     PS ++G  S +    P  
Sbjct: 1565 --------------------PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPA 1604

Query: 142  RMKPSPL-TPCPPGVPSPSP---PPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSM 197
               PSP   P PP V  PSP   P       T     +T S L+        P S T  M
Sbjct: 1605 VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS---PASVTCKM 1661

Query: 198  --LLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPR 255
               + +   G P ++ P   +E     AP P   P   A  R+    K S+A+  P  P 
Sbjct: 1662 GATVPQASKGLPAKKGPTALKE--VLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719

Query: 256  AADTPGT-APAPTPTPAPA---------AAPALTPSSGPGSAALTLEEELQEAIRRA--- 302
             +   G+  P  T  PAP           A     S  P       E +    +  A   
Sbjct: 1720 PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE 1779

Query: 303  QLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSS 362
            ++LP        E       P PP+ L    S  V +  P  + L S     L SP+   
Sbjct: 1780 KVLPKP------ESASVSAAPSPPVSLPLAPS-PVPTLPPKQQFLPSSPGLVLESPSKPL 1832

Query: 363  SPSPRDPTDSLDWLEALSGGPPLGS 387
            +P+  D    L   E +SGG P  S
Sbjct: 1833 APADEDELLPLIPPEPISGGVPFQS 1857



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 99/408 (24%), Positives = 136/408 (33%), Gaps = 54/408 (13%)

Query: 42   ASDPPL-APALPSGTAPFLF------------SPGVLLPEPEYCPPWRSPKKESPKISQR 88
            A+ PP  AP  P+ T P L             +P V+ P      P  SP K +P     
Sbjct: 1256 ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315

Query: 89   WRESK--------PRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEG------T 134
               S         P+G  T     PP P+           S  GP  PS  EG      T
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375

Query: 135  DSQQPHPRMKPSPLTPCPPGVPSPSPPPHK---LELQTLKLEELTVSELRQQLRLRG--- 188
             S +  P M P P     P +PSP   P     + L   K     V+        +G   
Sbjct: 1376 PSHKGGPAMTP-PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434

Query: 189  ----LPVSGTKSMLLERMRGG-APPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVK 243
                 PVS  K+      +GG A P  +  P     PA  P    +P A        S K
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDP---TLPAVTPPSPKEPPAPKQVATSSSPK 1491

Query: 244  PSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQ 303
             + A+   P P  A T       +P   PA   +      P +  L+ +     A + A 
Sbjct: 1492 KAPAT---PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548

Query: 304  LLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSP---SPDS-EGLSSVFSSSLPSPT 359
            + P   +      +  P  P P      P S +  SP   +P + +G  S     +P   
Sbjct: 1549 IPPAMTVP---SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV 1605

Query: 360  NSSSP--SPRDPTDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSSSS 405
             S SP  +P  P  +    E     P     P  P +  + L DS +S
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 56/208 (26%), Positives = 81/208 (38%), Gaps = 33/208 (15%)

Query: 176 TVSELRQ-QLRLRGLPVSGTKSMLLERMRGGA--PPRERPKPRRED-SPAGAPWPRLKPK 231
           T  EL Q Q     LP+S   S+     + G   PP   P P++   S A    P   P 
Sbjct: 12  TEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPS 71

Query: 232 ALAAARRQGSVKPSAASHRPPLPRAADTPGTAP---APTPTPA------PAAAPAL--TP 280
            +A+   +     S++    PL  A + P   P    P  +PA      P  AP L  TP
Sbjct: 72  TIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTP 131

Query: 281 SSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLS- 339
           SS   SA L L      +++++   P     ++L          P + +   GS   LS 
Sbjct: 132 SS---SAPLALVALAPHSVQKSSAFP----PNLLTSP-------PSVAVAESGSVITLSA 177

Query: 340 ---PSPDSEGLSSVFSSSLPSPTNSSSP 364
              PS     L+ V S  +P+P  + SP
Sbjct: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSP 205



 Score = 29.3 bits (64), Expect = 6.9
 Identities = 43/181 (23%), Positives = 67/181 (37%), Gaps = 30/181 (16%)

Query: 233 LAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLE 292
           ++ A +   VK    +  P +P A++    AP+P  T AP A   L P            
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP------------ 728

Query: 293 EELQEAIRRAQLLP------NRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEG 346
            E+ +++    L P       + +D I         P+   P + P      S +  S+G
Sbjct: 729 -EIPKSVPSPSLPPAGTPPGTKKVDGI--SHTSALAPVASSPKECPTEDSGASATASSKG 785

Query: 347 LSSVFSSSLPSPTN-SSSPSPRDPTDSLDWLEALSGGP--PLGSGPPPPSIFSADLSDSS 403
             +  + S PSP   S SP  + P          S GP  P+G+   P S   A     +
Sbjct: 786 TLTYLADS-PSPLGVSVSPQTKRPPTKKG-----SAGPDTPIGNLSSPVSPVEASFLPEN 839

Query: 404 S 404
           S
Sbjct: 840 S 840


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 118/474 (24%), Positives = 160/474 (33%), Gaps = 117/474 (24%)

Query: 30   QEQISDPDPWISASDPPLAPALPSGTAPFLFSPGVLLPE-PEYCP----PWRSPKKESPK 84
            ++  + P P  S + PP   +L S   P   SP + LPE P+ CP    P  SP+ E P 
Sbjct: 694  EDSPTSPPPEDSPASPPPEDSLMS--LPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPH 751

Query: 85   ISQRWRES--KPRGNLTYHQYMPPEP-----RQGSRADPQAEGSALGPPGPSLWEGTDSQ 137
            +S R  E    P+    +    P EP      +     PQAEG  L P    L     ++
Sbjct: 752  LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE 811

Query: 138  QPH--------------------------------------PRMKPSPLTPCP------P 153
            +PH                                      P ++  PL+P P      P
Sbjct: 812  EPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP 871

Query: 154  G-VPSPS-----PPPHKLELQTLKLE-------ELTVSELRQQLRLRGLPVSGTKSMLLE 200
            G  P+P      PPP +  L  L  E       E  +S L ++L L     SG  S+  +
Sbjct: 872  GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSP---SGEPSLSPQ 928

Query: 201  RMRGGAPPRERPKPRREDSPAGAPWPRLKP--KALAAARRQGSVKPSAASHRPPLPRAAD 258
             M    PP   P P      A AP P L P  +       +G   P +    P L     
Sbjct: 929  LM----PPDPLPPPLSPIITAAAP-PALSPLGELEYPFGAKGDSDPESPLAAPILETPIS 983

Query: 259  TPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQV 318
             P  A    P P P      +P S  G A+  L E L    + + LL +     ++    
Sbjct: 984  PPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP--QCSPLLQH----SLVPQNS 1037

Query: 319  EPDDPLPP-IPLDFPGSFDVLS-------------------PSPDSEGLSSVFSSSLPSP 358
             P    PP +PL  P     +                      P+   L    +S LPSP
Sbjct: 1038 PPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP 1097

Query: 359  TNSSS---PSPRDPTDSLDWL----EALSGGPPLGSGPPP---PSIFSADLSDS 402
                S   PSP    D    L      L G    GS P P   P   +++L  S
Sbjct: 1098 MGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGS 1151



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 73/282 (25%), Positives = 98/282 (34%), Gaps = 22/282 (7%)

Query: 105 PPE------PRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPR--MKPSPLTPCPPGVP 156
           PPE      P + S   P  E S L PP   L      +  H    ++ SPL+P PP   
Sbjct: 443 PPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSP-PPEES 501

Query: 157 SPSPPPHKLELQTLKLEELTVSELRQ-----QLRLRGLPVSGTKSMLLERMRGGAPPRER 211
             SPPP       L+   L+  E        +  L   P +   S   E      PP E 
Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561

Query: 212 PKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPA 271
           P     ++   +P P   P +        S  P A+   PP   +  +P   P  +P   
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP--PPEESPLSP 619

Query: 272 PAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDF 331
           P  A  L+P       +   EE           L    +   L    E + PL P P + 
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPE-ESPLSPPPEES 678

Query: 332 PGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSL 373
           P      SP P++  LS     S  SP    SP+   P DSL
Sbjct: 679 P-----TSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSL 715



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 104/393 (26%), Positives = 131/393 (33%), Gaps = 54/393 (13%)

Query: 36  PDPWISASDPPL--APALPSGTAPFLFSP---GVLLPEPEYCPPWRSPKKESPKISQRWR 90
           P P  S   PP   +P  P   A  LF P     L P PE  P   SP  E+ ++S    
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESP--LSPPPEASRLSPP-P 630

Query: 91  ESKPRGNLTYHQYMPPEPRQG--------SRADPQAEGSALGPPGPSLWEGTDSQQPHP- 141
           E  P         M P P           SR  P  E S L PP     E   S  P   
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE---ESPTSPPPEAS 687

Query: 142 RMKPSP--LTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLL 199
           R+ P P      PP   SP+ PP +  L +L LEE  +  L ++ +L         S   
Sbjct: 688 RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747

Query: 200 ERMRGGAPPRERPKPRREDSPAGAPWPRLKPK----ALAAARRQGSVKPSA-ASHRPPLP 254
           E       P   P+P        A  P L P+     L A   +  + P A   H  P P
Sbjct: 748 EE------PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQP 801

Query: 255 RAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDIL 314
                      P  +P P   P L+P   P  + L+ + E          L  R  +  L
Sbjct: 802 EELHLSPQTEEPHLSPVP-EEPCLSPQ--PEESHLSPQSE-------EPCLSPRPEESHL 851

Query: 315 EDQVE--PDDPLPPIPLDFPGSFDV-----LSPSPDSEGLSSVFSSSLPSPTNSSSPSPR 367
             ++E  P  P P  P + PG         L P P    LS +      S       SP 
Sbjct: 852 SPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPL 911

Query: 368 DPTDSLDWLEALSGGPPLGSGPPPPSIFSADLS 400
                L    + SG P L     PP      LS
Sbjct: 912 PEELPL----SPSGEPSLSPQLMPPDPLPPPLS 940



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 92/353 (26%), Positives = 113/353 (32%), Gaps = 47/353 (13%)

Query: 74  PWRSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEG 133
           P  +P  E   +    +     G++T  Q   P P Q        E   LG  G  L   
Sbjct: 377 PGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQ-------CEAKPLGKAGVQL--- 426

Query: 134 TDSQQPHPRMKPSPLTPCPPGVPSP----------SPPPHKLELQTLKLEELTVSELRQQ 183
            + Q   P  +  PL P P    SP          SPPP    L     EEL  S L + 
Sbjct: 427 -EPQLEAPLNEEMPLLPPPE--ESPLSPPPEESPTSPPPEASRLSP-PPEELPASPLPEA 482

Query: 184 LRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVK 243
           L L         S   E      PP   P    E+SP   P       AL       S  
Sbjct: 483 LHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL---SPP 539

Query: 244 PSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQ 303
           P A+   PP   +  +P     PT  P  A+  +  P   P S     E  +      ++
Sbjct: 540 PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP-PEESPMSPPPEASR 598

Query: 304 LLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSS 363
           L P                P    PL  P     LSP P++  LS     S  SP    S
Sbjct: 599 LFP----------------PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642

Query: 364 P-SPRDPTDSLDWLEALS--GGPPLGSGPPPPSIFSADLSDSSSSRLWDLLED 413
           P SP      L  L  +S    PP  S   PP   S       +SRL    ED
Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED 695



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 58/195 (29%), Positives = 80/195 (41%), Gaps = 20/195 (10%)

Query: 218  DSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPA-PTPTPAPAAAP 276
            DSP G  + +L P+  A    Q       A   P  PR    P T P  P+PT APA  P
Sbjct: 2154 DSP-GELFLKLPPQVPAQVPSQDPF--GLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP 2210

Query: 277  ALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPG--- 333
             L  SS PG+              R Q  P+   D  L+ +    D L  +P + PG   
Sbjct: 2211 MLGASSRPGAGQPGEFHTTPPGTPRHQ--PSTP-DPFLKPRCPSLDNL-AVP-ESPGVGG 2265

Query: 334  ---SFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGS-GP 389
               S  +LSP P  E   ++          +SSPS   P  +L ++++ S G  LG    
Sbjct: 2266 GKASEPLLSPPPFGESRKAL--EVKKEELGASSPSYGPP--NLGFVDSPSSGTHLGGLEL 2321

Query: 390  PPPSIFSADLSDSSS 404
              P +F A L+  +S
Sbjct: 2322 KTPDVFKAPLTPRAS 2336



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 70/294 (23%), Positives = 102/294 (34%), Gaps = 62/294 (21%)

Query: 30   QEQISDPDPWISASDPPLAPALPSGTAPFLFSPGV---LLPEPEYCPPWRSPKKESPKIS 86
            + Q S PDP++     P  P+L +   P   SPGV      EP   PP   P  ES K  
Sbjct: 2235 RHQPSTPDPFLK----PRCPSLDNLAVPE--SPGVGGGKASEPLLSPP---PFGESRKAL 2285

Query: 87   QRWRESKPRGNLTYHQ-------------------------YMPPEPRQGSRADPQAEGS 121
            +  +E     + +Y                           +  P   + S+ +PQ+ G 
Sbjct: 2286 EVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGL 2345

Query: 122  ALGPPGPSLWEGTDSQQP-HPRM-KPSPLTPC---PPGVPSPSPPPHK----LELQTLKL 172
             L P  P   +      P HP + +P   T     PP  P P PPP +    L  ++L  
Sbjct: 2346 GLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPS 2405

Query: 173  EELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKA 232
            +  +      Q +      S ++S L  R          P   R  SP     P  +P+ 
Sbjct: 2406 DPFSRVPASPQSQ------SSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ- 2458

Query: 233  LAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAA-PALTPSSGPG 285
                    S  P A  H+PP P+  +    A +   T   A   PA  P+   G
Sbjct: 2459 --------SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 27/90 (30%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 141  PRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLE 200
            P  +PSP  P  P  PSP+ PP      T  L EL    L +      LP++ +      
Sbjct: 4910 PPEEPSP--PPSPLAPSPASPP------TEPLVELPTEPLAEPPVPSPLPLASSPESARP 4961

Query: 201  RMRGGAPPR-ERPKPRREDSPAGAPWPRLK 229
            + R   P   E  +P R     G  W RL+
Sbjct: 4962 KPRARPPEEGEDSRPPRLKKWKGVRWKRLR 4991



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 14/86 (16%)

Query: 108  PRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSP---------LTPCPPGVPSP 158
            PR  +     + G  LGP  P+    +  +   P   PSP         L P  PG P P
Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346

Query: 159  -----SPPPHKLELQTLKLEELTVSE 179
                  PPP ++     +L +   S+
Sbjct: 4347 QGPTLEPPPGRVSPAAAQLADTLFSK 4372


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 115/461 (24%), Positives = 156/461 (33%), Gaps = 112/461 (24%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCP--PWRSPKKESPKISQRWRES 92
           DP   +  S PP  P       PF++ P +  P P Y P  P+R P  + P  S+  R +
Sbjct: 230 DPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFP-PPYGPQGPYRYPTPDGP--SRFPRVA 286

Query: 93  KPRGNLTYHQYMPP------------------------------------------EPRQ 110
            PRG+    + + P                                          +   
Sbjct: 287 GPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEED 346

Query: 111 GSRADPQ-AEG-----SALGPPGPSLWEG-----TDSQQPHPR------MKPSPLTPCPP 153
           G  +D + AEG     SA G   P   +G      +S+ P P+       +P    P PP
Sbjct: 347 GRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPP 406

Query: 154 GVPSPSPPPHK------------LELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLER 201
               P PPPH+             +      +     +  +  R R    S   S+ +ER
Sbjct: 407 APKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVER 466

Query: 202 MRGGAPPRER-----------PKPRREDSPAGAPWPRLK--PKALAAARRQGSVKPSAAS 248
            R      ER            K +R D   GAP  RLK  P A  AA    +  P+   
Sbjct: 467 ARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPK 526

Query: 249 HRP----PLPRAADTPGTAP-----AP----TPTPAPAAAPALTPSSGPGSAALTLEEEL 295
             P    P P +A TP T P     AP    TPTP  AAAP L   SG GS + T     
Sbjct: 527 ELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLV--SGGGSTSSTSSGSF 584

Query: 296 QEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPS--PDSEGLS-SVFS 352
           + +    QL    G +     +  P    PP+P   P   D + P+  P S+GL    + 
Sbjct: 585 EASPVEPQLPSKEGPE---PPEEVPPPTTPPVPKVEPKG-DGIGPTRQPPSQGLGYPKYQ 640

Query: 353 SSLPSP-TNSSSPSPRDPTDSLDWLEALSGGPPLGSGPPPP 392
            SLP                   W +   G  P    PP P
Sbjct: 641 KSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSP 681



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 83/356 (23%), Positives = 121/356 (33%), Gaps = 52/356 (14%)

Query: 85   ISQRWRESKPRGNLTYHQYMPPEPRQGSRADP--------QAEGSALGPPGPSLWEGTDS 136
            +SQR ++   R   ++    P   RQ  R  P         + G   G PG     G   
Sbjct: 1373 LSQRAKDLSKR---SFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGD 1429

Query: 137  QQ--PHPRMKPSPLTPCPPGVPSPSPPPHKLEL----QTLKLEELTVSELRQQLRLRGLP 190
            ++  P P+ +  P    PPG+P P PPP    +    Q +      + +   QL  R   
Sbjct: 1430 KRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGS 1489

Query: 191  VSGT------KSMLLERMRGGAP-PRERPKPRREDSPAGA------PWPRLKPKALAAAR 237
            V+        K  L +  +G +P P  R +P+R +S   +      P P ++       R
Sbjct: 1490 VTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVG-GTPR 1548

Query: 238  RQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPA------PAAAPALTPSSGPGSAALT- 290
                V P     R   PR  +       P P  +      P        S   G+ ALT 
Sbjct: 1549 DSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTP 1608

Query: 291  -LEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIP----LDFPGSFDVLSPSPDSE 345
             +   L  A  R    P+      +E  +EP  P   +            D+   S  S 
Sbjct: 1609 HIWNRLHTATSRKSYRPSS-----MEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSS 1663

Query: 346  GLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGSGP---PPPSIFSAD 398
            G  S  SS       ++   P+ P  S         GPP GS P   PPP+    D
Sbjct: 1664 GPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPP-GSEPPRRPPPAPHDGD 1718



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 57/249 (22%), Positives = 81/249 (32%), Gaps = 37/249 (14%)

Query: 27  RRNQEQISDPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKIS 86
           +R  E+   PD  + A +P   PA PS  AP    P  L P P   PP  +P  E+    
Sbjct: 491 KRLDEKFGAPDKRLKA-EPAAPPAAPSTPAPPPAVPKEL-PAPPAPPPASAPTPETE--- 545

Query: 87  QRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPS 146
                             P EP Q   A           P      G+ S       + S
Sbjct: 546 ------------------PEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEAS 587

Query: 147 PLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGA 206
           P+ P  P    P PP       T  + ++           +G  +  T+    + +  G 
Sbjct: 588 PVEPQLPSKEGPEPPEEVPPPTTPPVPKVEP---------KGDGIGPTRQPPSQGL--GY 636

Query: 207 PPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAP 266
           P  ++  P R          + + +      +QGS  P+     PP P    T G  PAP
Sbjct: 637 PKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPV---TLGAVPAP 693

Query: 267 TPTPAPAAA 275
              P P  A
Sbjct: 694 QAPPPPPKA 702



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 96/403 (23%), Positives = 126/403 (31%), Gaps = 89/403 (22%)

Query: 46  PLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRW-----RESKPRGNLTY 100
           P+ P LPS   P           PE  PP  +P    PK+  +          P   L Y
Sbjct: 588 PVEPQLPSKEGP---------EPPEEVPPPTTPPV--PKVEPKGDGIGPTRQPPSQGLGY 636

Query: 101 HQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPP------G 154
            +Y    P +  R   Q +   L       W+    Q       P+P+ P PP       
Sbjct: 637 PKYQKSLPPRFQR---QQQEQLLKQQQQHQWQ----QHQQGSAPPTPVPPSPPQPVTLGA 689

Query: 155 VPSPS--PPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMR-GGAPPRER 211
           VP+P   PPP K            +  +    R   +P      +L  R      PP   
Sbjct: 690 VPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVH 749

Query: 212 PK---PRREDSPAGAPWPRLKPKALAAARRQGS--VKP-----------SAASHRP---P 252
           P    PR      G+        A A  R +G+  V P           + A  RP   P
Sbjct: 750 PSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSP 809

Query: 253 LPRAADTPG------TAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLP 306
           L +AAD         T P P P P  A+ P    +  PG         L+E   R    P
Sbjct: 810 LRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRF--PLEEPGPRPLPWP 867

Query: 307 NRGIDDILEDQVEPDDPLPP--------------IPLDFPGSFDVLSPSPDSEGLSSVFS 352
             G D++ + Q  P    PP               P    GS     P P  E  +    
Sbjct: 868 -PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRW 926

Query: 353 SSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGSGP---PPP 392
              P  +    P P +P           G PP  +GP   PPP
Sbjct: 927 GPRPGSSRRGIP-PEEP-----------GAPPRRAGPIKKPPP 957



 Score = 35.8 bits (81), Expect = 0.073
 Identities = 83/333 (24%), Positives = 113/333 (33%), Gaps = 53/333 (15%)

Query: 97   NLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKP-SPLTPC---- 151
            NL     +P     G R  P+    + GP    +  G    Q HP      P TP     
Sbjct: 1815 NLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPY 1874

Query: 152  -------PPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGT----KSMLLE 200
                   PPG   P+PP   L    LK + L  S + Q   L  LP  G      S L  
Sbjct: 1875 RSQPLYLPPG---PAPPSALLSGLALKGQFLDFSTM-QATELGKLPAGGVLYPPPSFLYS 1930

Query: 201  RMRGGAP-PRERPKPRREDSPAGAPW--PRLKPKALAA-----ARRQGSVKPSAASHRPP 252
                 +P P       R+D P+ + +    L+P   +      A  Q  + P   S  P 
Sbjct: 1931 PAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPV 1990

Query: 253  LPRAADTPGTAPAPTPTPAPAAAPALTPSS-----GPGSAALTLEEELQ---EAIRRAQL 304
            +   +  P   PAP P       PAL P S      P  A   L    +    ++ RA+L
Sbjct: 1991 VNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAEL 2050

Query: 305  LP--NRGIDDILEDQVEPDDP----LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSP 358
             P   +   D  +       P     PP    F G    L  +P +   S VF +     
Sbjct: 2051 HPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPST--YSGVFRTQRVDL 2108

Query: 359  TNSSSPSPRDPTDSLDWLEALSGGPPLGSGPPP 391
               +S     P D+L W+      P   +GPPP
Sbjct: 2109 YQQAS-----PPDALRWIPK----PWERTGPPP 2132



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 52/205 (25%), Positives = 71/205 (34%), Gaps = 18/205 (8%)

Query: 27   RRNQEQISDPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCP-PWRSPKKESPKI 85
            R     +  P P++++      P  P   AP        L EP   P PW     E  KI
Sbjct: 822  RSETPPVPPPPPYLASY-----PGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKI 876

Query: 86   SQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQ-PHPRMK 144
                 + +P    T     P   R+ +R          GPP P     T+++  P P   
Sbjct: 877  QTPPPKKEPPKEETAQLTGPEAGRKPARG---VGSGGQGPPPPRRESRTETRWGPRPGSS 933

Query: 145  PSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRG 204
               + P  PG P     P K      K+EEL    L Q       P      +   ++ G
Sbjct: 934  RRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGG 993

Query: 205  GAPPRERPKPRREDSPAGAPWPRLK 229
               P+E P P    SPA    PRL+
Sbjct: 994  ---PKETP-PNGNLSPA----PRLR 1010



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 52/190 (27%), Positives = 65/190 (34%), Gaps = 41/190 (21%)

Query: 124  GPPGPSLWEGTDSQQPHPRMKPSPLTPCPPG---VPSPSPPPHKLELQTLKLEELTVSEL 180
            G PGP +     S+ P     P PL P PPG   V     PP K E    +  +LT  E 
Sbjct: 845  GAPGPPI-----SRFPLEEPGPRPL-PWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEA 898

Query: 181  RQQLRL------RGLPVSGTKSMLLERM-------RGGAPPRERPKPRREDSPAGAPWPR 227
             ++         +G P    +S    R        R G PP E   P R   P   P P 
Sbjct: 899  GRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPP 958

Query: 228  LKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTP---TPAPAAAPALTPSSGP 284
             K + L                  PL +  +TP   P P P   T      P  TP +G 
Sbjct: 959  TKVEELPP---------------KPLEQGDETP-KPPKPDPLKITKGKLGGPKETPPNGN 1002

Query: 285  GSAALTLEEE 294
             S A  L  +
Sbjct: 1003 LSPAPRLRRD 1012



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 13/75 (17%)

Query: 92   SKPRGNLTYHQYMPPEPRQ-GSRADPQAEGSALGPPGPSLWEGTDSQQPHPR---MKPSP 147
            S+ R   + ++ +P   RQ GS    +   S L P        +D + P P+   +   P
Sbjct: 1085 SETRSEGSEYEEIPKRRRQRGSETGSETHESDLAP--------SDKEAPTPKEGTLTQVP 1136

Query: 148  LTPCPPGVPSPSPPP 162
            L P PPG P PSP P
Sbjct: 1137 LAPPPPGAP-PSPAP 1150



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 45/171 (26%), Positives = 54/171 (31%), Gaps = 30/171 (17%)

Query: 113  RADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKL 172
            R  P   G   G P P +  G          K  P  P P     PS  P K        
Sbjct: 1164 RGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLP-----PSKEPLK-------- 1210

Query: 173  EELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKA 232
            E+L    L    R       G+       M  G  PR R   R +       + RLK + 
Sbjct: 1211 EKLIPGPLSPVAR------GGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQER 1264

Query: 233  LAAARRQGSVKPSAASHRPPLPRAADTPGTAPA---PTPTPAPAAAPALTP 280
              AAR         +  +P L   A  PG   A    T  PAP  A A +P
Sbjct: 1265 ENAAR--------GSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSP 1307


>gi|62955044 F-box protein 42 [Homo sapiens]
          Length = 717

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 80/264 (30%), Positives = 110/264 (41%), Gaps = 39/264 (14%)

Query: 46  PLAPALPSGTAPFLFSPGVLLPEP-EY--CPPWRSPKKESPKISQRWRESKPRGNLTYHQ 102
           PL+P+L S  +P   +P  L+PE  EY    P RS   E+P ++ RW   +PR      +
Sbjct: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRA----QR 417

Query: 103 YMPPEPRQGSRADPQAEGSALGPPGPSLWEGT----DSQQPHPRMKPSPLTP-CPPGVP- 156
             P   R+GS +  + +GS +   G SL  GT     S    P    SP TP  P G   
Sbjct: 418 QTPSGSREGSLSPARGDGSPI-LNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476

Query: 157 --SPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSM--LLERMRGGA---PPR 209
               S  P +  L   K   L   +L   L+    P S +  M  +  R  GG+   PP 
Sbjct: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLK----PASSSNPMDGMDNRTVGGSMRHPPE 532

Query: 210 E----RPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSA-ASHRPPLPRAADTPG--- 261
           +       P    + AGA  P    ++L A +   S  PSA A+  PPL  +  +PG   
Sbjct: 533 QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQS 592

Query: 262 -----TAPAPTPTPAPAAAPALTP 280
                T P P P PA     +L P
Sbjct: 593 LSSGETVPIPRPGPAQGDGHSLPP 616



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 72/269 (26%), Positives = 95/269 (35%), Gaps = 46/269 (17%)

Query: 153 PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
           P +  PSP P   + Q + +++ T+  L       G P +  K   L  M  G    +  
Sbjct: 273 PNISGPSPHPRGGQSQIV-IDDATILILGGC----GGPNALFKDAWLLHMHSGPWAWQPL 327

Query: 213 KPRREDSPAGAPWPRLKPKALAAARRQGS---VKPSAASHRPPLPRAADTPGTAPAPTPT 269
           K   E+  A   W          A R G    V   A S R PL  + ++        P+
Sbjct: 328 KVENEEHGAPELWCH-------PACRVGQCVVVFSQAPSGRAPLSPSLNS-------RPS 373

Query: 270 PAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPN-RGIDDILEDQVEPDDP----- 323
           P  A  PAL P         T E   Q  +R     P   G    L  + +   P     
Sbjct: 374 PISATPPALVPE--------TREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSRE 425

Query: 324 --LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSG 381
             L P   D  GS  +L+    S G ++V  SSL SP  + SPS     +  D    LS 
Sbjct: 426 GSLSPARGD--GS-PILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSL 482

Query: 382 GPPLGSGPPPPSIFSADLSDSSSSRLWDL 410
            P  GS P        DL   S    WDL
Sbjct: 483 APRRGSLPD-----QKDLRLGSIDLNWDL 506


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 92/404 (22%), Positives = 140/404 (34%), Gaps = 82/404 (20%)

Query: 68  EPEYCPP---------WRSPKKESPKISQRWRESKP---------------------RGN 97
           E +Y PP         W S ++ SP++ Q    S P                      G 
Sbjct: 490 ENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGG 549

Query: 98  LTYHQYMP-PEPRQGSRAD-------PQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLT 149
           + +    P P  R  SR         P+A      P  P          P     P+P++
Sbjct: 550 VPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVS 609

Query: 150 PCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPR 209
             P  + S  PP             ++    R     R     G+ S  LE +    P  
Sbjct: 610 TMPKRMSSEGPP------------RMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSE 657

Query: 210 ERPKPRREDSPAGAPW-------PRLKPKA-LAAARRQGSVKPSAASHRPPLPRAADTPG 261
               P    SP+G  W       PRL PK     + RQ S+  + +      P+A   P 
Sbjct: 658 AATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPT 717

Query: 262 TA-----PAPTPTPA-PAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLP--------- 306
            A     PA +PTPA PA+  A+TPSS    + L  + +   A  +  + P         
Sbjct: 718 EAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSK 777

Query: 307 --NRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSP 364
             N+GI  ++ +  +  D L     DF      L PS  SE +  + + +     +    
Sbjct: 778 AENKGISPVVSEHRKQIDDLKKFKNDFR-----LQPSSTSESMDQLLNKNREGEKSRDLI 832

Query: 365 SPR-DPTDSLDWLEALSGGPPLGSGPP-PPSIFSADLSDSSSSR 406
             + +P+    ++E  S     GS  P  PSI  + LS++   R
Sbjct: 833 KDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKR 876



 Score = 36.6 bits (83), Expect = 0.043
 Identities = 61/248 (24%), Positives = 87/248 (35%), Gaps = 53/248 (21%)

Query: 145 PSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRG 204
           P P     P  P P PPP +                      +  P S +         G
Sbjct: 47  PGPYPSAAPPPPGPGPPPSR----------------------QSSPPSASDCFGSNGNGG 84

Query: 205 GAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAP 264
           GA    RP  RR     G P P +    L          P+A +   PL   A  P +  
Sbjct: 85  GA---FRPGSRRLLGLGGPPRPFV---VLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138

Query: 265 APTPTPAPAAA-PALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDP 323
           +    PAP    PA  P  GP + +L  +++ Q+  ++ Q           + Q +    
Sbjct: 139 S-LARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQ----------QQQQQQQQQQ 187

Query: 324 LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPT-NSSSPSPRDPTDSLDWLEALSGG 382
            PP     P + +V  P     G S + +S   +P+ +SSS S    T     + A SGG
Sbjct: 188 QPP-----PAAANVRKP-----GGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGG 237

Query: 383 --PPLGSG 388
             P LG G
Sbjct: 238 GRPGLGRG 245


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 76/301 (25%), Positives = 108/301 (35%), Gaps = 55/301 (18%)

Query: 126 PGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQT---------LKLEELT 176
           P P +     + QP P + P P  P PP  P P PPP  L  Q+         + ++  T
Sbjct: 611 PQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP-PLPSQSAPSAGSAAPMFVKYST 669

Query: 177 VSELRQQLRLRG----------LPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWP 226
           ++ L+   +  G          +     K  +L    G  PP   P P       G+   
Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPP---PPPPPPPPTPGSAMA 726

Query: 227 RLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGS 286
           +LKP   A +  Q S  P      PPL        T  AP   P P   PA  P   P  
Sbjct: 727 QLKPAPCAPSLPQFSAPP------PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780

Query: 287 AALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIP-----LDFPGSFDVLSPS 341
             +T+                + +  ++  Q  P  P PP+P       FP S+  + PS
Sbjct: 781 PLVTIPAPTS----------TKTVAPVV-TQAAPPTPTPPVPPAKKQPAFPASY--IPPS 827

Query: 342 PDSEGLSSVFSSSLPSPTN---SSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPSIFSAD 398
           P +  +  V   +LP   +      PSP  P  S+    A    PP    P PP++ S  
Sbjct: 828 PPTPPV-PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP----PTPPAMESQP 882

Query: 399 L 399
           L
Sbjct: 883 L 883



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 92/392 (23%), Positives = 127/392 (32%), Gaps = 92/392 (23%)

Query: 36  PDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           P P      PP  P LPS +AP   S G   P                            
Sbjct: 634 PPPPPPPPPPPPPPPLPSQSAP---SAGSAAP---------------------------- 662

Query: 96  GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGV 155
               + +Y      Q +    Q  G+   PP P + +          +KP  L P P GV
Sbjct: 663 ---MFVKYSTITRLQNA---SQHSGALFKPPTPPVMQSQS-------VKPQILVP-PNGV 708

Query: 156 PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPR 215
             P PPP         + +L  +     L     P    K   ++ +   APP   P P 
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP- 767

Query: 216 REDSPAGAPWPRLKPKALAAARRQGSVKPSA--------ASHRPPLPRAADTPG-----T 262
               PA  P P+  PK L       S K  A         +  PP+P A   P       
Sbjct: 768 --PIPAPLP-PQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824

Query: 263 APAPTPTPAPAAAPAL--------TPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDIL 314
            P+P   P P   P L         P   P S   ++ +++      A   P       +
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI------ASQFPPPPTPPAM 878

Query: 315 EDQVEPDDPLPPIPLDF-PGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSL 373
           E Q     PL P+P +  P S   +   P  +       SS+P P+    P P  P  SL
Sbjct: 879 ESQ-----PLKPVPANVAPQSPPAVKAKPKWQ------PSSIPVPSPDFPPPP--PESSL 925

Query: 374 DWLEALSGGPPLGSGPPPPSIFSADLSDSSSS 405
            +        P+ + PPPP   ++   D S S
Sbjct: 926 VFPPPPPS--PVPAPPPPPPPTASPTPDKSGS 955



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 72/328 (21%), Positives = 109/328 (33%), Gaps = 53/328 (16%)

Query: 46   PLAPALPSGTAPFLFSPGVLLPEPEY----CPPWRSPKKESPKISQRWRESKPRGNLTYH 101
            P AP+LP  +AP    P + + + ++     PP   P    P         KP   +   
Sbjct: 732  PCAPSLPQFSAP---PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTI--- 785

Query: 102  QYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPP 161
                P P       P    +A   P P +       +  P    S + P PP  P P PP
Sbjct: 786  ----PAPTSTKTVAPVVTQAAPPTPTPPV----PPAKKQPAFPASYIPPSPPTPPVPVPP 837

Query: 162  PHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPA 221
            P      TL  ++   ++          P+S   S++ +++    PP   P P  E  P 
Sbjct: 838  P------TLPKQQSFCAKPPPS------PLSPVPSVV-KQIASQFPPPPTP-PAMESQPL 883

Query: 222  GAPWPRLKPKALAAARRQGSVKPSA----ASHRPPLPRAADTPGTAPAPTPTPAPAAAPA 277
                  + P++  A + +   +PS+    +   PP P  +      P P+P PAP   P 
Sbjct: 884  KPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP 943

Query: 278  LTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDV 337
             T S  P  +                  P +          +   P P        S   
Sbjct: 944  PTASPTPDKSG----------------SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987

Query: 338  LSPSPDSEGLSSVFSSSLPSPTNSSSPS 365
              P P    + S+ S   P P  S SPS
Sbjct: 988  EHPEPKRPSVDSLVSKFTP-PAESGSPS 1014



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 47/193 (24%), Positives = 67/193 (34%), Gaps = 27/193 (13%)

Query: 225 WPRLKPKALAAARRQGSVKPSAASHRPPL--------PRAADTPGTAPAPTPTPAPAAAP 276
           W R      ++  R  S+     S  PPL        P  A  P     P P P P   P
Sbjct: 581 WKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPP 640

Query: 277 ALTPSSGP---------GSAA-----LTLEEELQEAIRRAQLLPNRGIDDILEDQ-VEPD 321
              P   P         GSAA      +    LQ A + +  L       +++ Q V+P 
Sbjct: 641 PPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQ 700

Query: 322 DPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSG 381
             +PP  +  P       P+P S       +   PS    S+P P      +  +  ++ 
Sbjct: 701 ILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVA- 759

Query: 382 GPPLGSGPPPPSI 394
            PP  + PPPP I
Sbjct: 760 -PP--TPPPPPPI 769


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 71/341 (20%), Positives = 113/341 (33%), Gaps = 50/341 (14%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P  +    P  P  P+ T P    P    P+    P   +PK+ +P  +++   + P
Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKE---PAPTTPKEPAPTTTKKPAPTTP 471

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPG 154
           +      +  P  P++ +   P+     L P  P     T  ++P P   P  L P  P 
Sbjct: 472 K------EPAPTTPKETAPTTPKK----LTPTTPEKLAPTTPEKPAPTT-PEELAPTTPE 520

Query: 155 VPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKP 214
            P+P+ P              T  E          P +  +           P    PK 
Sbjct: 521 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-----------PAPTTPKE 569

Query: 215 RREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTP------GTAPAPTP 268
               +P G     LK  A    ++    + +  + + P     D P      GTAP    
Sbjct: 570 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629

Query: 269 TPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIP 328
            PAP       P++  G+A  TL+E        A   P +               L P  
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEP-------APTTPKK----------PAPKELAPTT 672

Query: 329 LDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDP 369
              P S     P+P +   ++  +   P+PT    P+P  P
Sbjct: 673 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 713



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 72/343 (20%), Positives = 119/343 (34%), Gaps = 48/343 (13%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P  +    P  P  P+ T     +P      P       +PK+ +P   ++   + P
Sbjct: 261 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT------TPKEPAPTTPKKPAPTTP 314

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRM--KPSPLTPCP 152
           +      +  P  P++ +   P+        P P     T  ++P P    KP+P TP  
Sbjct: 315 K------EPAPTTPKEPTPTTPKEPAPTTKEPAP-----TTPKEPAPTAPKKPAPTTPKE 363

Query: 153 PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
           P   +P  P       T K    T  +       +  P +  +            P+E P
Sbjct: 364 PAPTTPKEPAPT----TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-P 418

Query: 213 KPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAP 272
            P     PA        PK  A    +   KP+  + + P P     P  AP  T  PAP
Sbjct: 419 SPTTTKEPAPTT-----PKEPAPTTPK---KPAPTTPKEPAPTTPKEP--APTTTKKPAP 468

Query: 273 AAAPALTPSSGPGSAALTLEEELQEAI--RRAQLLPNRGIDDILED--QVEPDDPLPPIP 328
                  P++ P   A T  ++L      + A   P +      E+     P++P P  P
Sbjct: 469 TTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 527

Query: 329 LDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTD 371
            +         P+P +   ++  +   P+PT    P+P  P +
Sbjct: 528 EE---------PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 79/366 (21%), Positives = 127/366 (34%), Gaps = 40/366 (10%)

Query: 36  PDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYC--PPWRSPKKESPKISQRWRESK 93
           P P       P  P  P+ T P   +P    P P     P   +PKK +P   +    + 
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368

Query: 94  PR--GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEG----------TDSQQPHP 141
           P+     T  +  P  P++ +    ++  +    P P+  +           T +++P P
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428

Query: 142 RM--KPSPLTPCPPGV-----PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGT 194
               +P+P TP  P       P+P+ P       T K    T  E          P +  
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 488

Query: 195 K--SMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPP 252
           K      E++    P +  P    E +P     P                 P AA+   P
Sbjct: 489 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-----TPTTPEEPAPTTPKAAAPNTP 543

Query: 253 LPRAADTPGTAPAPTP--TPAPAAAPALTPSSGPGSAALTLEEELQEAIRR---AQLLPN 307
              A  TP   PAPT    PAP       P++  G+A  TL+E      ++    +L P 
Sbjct: 544 KEPAPTTP-KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602

Query: 308 RGIDDILE--DQVEPDDP---LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSS 362
              +      D+  P  P    P  P + P       P+P +   ++  +   P+PT   
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 661

Query: 363 SPSPRD 368
            P+P++
Sbjct: 662 KPAPKE 667



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 60/303 (19%), Positives = 102/303 (33%), Gaps = 31/303 (10%)

Query: 73  PPWRSPKKESPKISQRWRESKPRGNL-TYHQYMPPEPRQGSRADPQAEGSALGPPGPSLW 131
           P   +PK+ +P   +    + P+    T  +  P  P++ +    ++  +    P P   
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP--- 264

Query: 132 EGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPV 191
             T +++P P    +P  P P     P+P   K    T K    T  +       +    
Sbjct: 265 --TTTKEPAPT---TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 319

Query: 192 SGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRP 251
           +  K       +  AP  + P P     PA        PK           KP+  + + 
Sbjct: 320 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA-----PK-----------KPAPTTPKE 363

Query: 252 PLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGID 311
           P P     P       P+P     PA T +    SA  T +E      + A   P     
Sbjct: 364 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK---SAPTTTKEPAPTTTKSAPTTPKEPSP 420

Query: 312 DILEDQVE--PDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDP 369
              ++     P +P P  P   P       P+P +    +  ++  P+PT    P+P  P
Sbjct: 421 TTTKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 479

Query: 370 TDS 372
            ++
Sbjct: 480 KET 482



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 68/280 (24%), Positives = 96/280 (34%), Gaps = 57/280 (20%)

Query: 48  APALPSGTAPFLFSPGVLLPE-PEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPP 106
           AP  P  TAP   +P  L P  PE   P  +P+K +P   +    + P       +  P 
Sbjct: 475 APTTPKETAPT--TPKKLTPTTPEKLAP-TTPEKPAPTTPEELAPTTPE------EPTPT 525

Query: 107 EPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRM--KPSPLTP------CPPGV--- 155
            P + +   P+A      P  P     T  ++P P    +P+P TP       P G    
Sbjct: 526 TPEEPAPTTPKAAA----PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 581

Query: 156 ----PSPSPP----PHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAP 207
               P+P+ P    P +L   T K    T  +       +G   +  K           P
Sbjct: 582 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----------P 631

Query: 208 PRERPKPRREDSPAGAPWPRLK-----------PKALAAARRQGSVKPSAASHRPPLPR- 255
               PK     +P G     LK           PK LA    +G    ++    P  P+ 
Sbjct: 632 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 691

Query: 256 AADTPGTAPAPT--PTPAPAAAPALTPSSGPGSAALTLEE 293
            A T    PAPT    PAP       P++   S   T +E
Sbjct: 692 TAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 731



 Score = 36.2 bits (82), Expect = 0.056
 Identities = 62/319 (19%), Positives = 101/319 (31%), Gaps = 53/319 (16%)

Query: 136 SQQPHPRMKPSP-LTPCPPGVPSPSPPPHKLELQ----------TLKLEELTVSELRQQL 184
           S   H ++  SP +T   P  P PS PP+    +          T++ +E T +  +   
Sbjct: 105 STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTST 164

Query: 185 RLRGLPVSGTKSMLLERMRGG--APPRE---RPKPRREDSPAGAPWPRLKPKALAAARRQ 239
             +    S  ++  +E+      AP  +   +P P+ E +  G      K       +  
Sbjct: 165 DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 224

Query: 240 GSVKPSAASHRPPLPRAADTPGTAPAPTPT---------PAPAAAPALTPSSGPGSAALT 290
            S  P   +  P   ++A T    PAPT T         PAP       P++    A  T
Sbjct: 225 ASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 282

Query: 291 LEEELQEAIRRAQLLPNRGIDDILEDQVE----------PDDPLPPIPLD---------- 330
            +E      + A   P        +              P +P P  P +          
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342

Query: 331 ----FPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLG 386
                P       P+P +    +  +   P+PT +  PSP  P +           P   
Sbjct: 343 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP--TTTKSAPTTT 400

Query: 387 SGPPPPSIFSADLSDSSSS 405
             P P +  SA  +    S
Sbjct: 401 KEPAPTTTKSAPTTPKEPS 419



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 17/135 (12%)

Query: 37  DPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRG 96
           +P  +  D P AP  P GTAP   +P    P     P   +PK  +P   +    + P+ 
Sbjct: 606 EPTSTTCDKP-APTTPKGTAPT--TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK- 661

Query: 97  NLTYHQYMPPEPRQGSRADPQAEGSALGP-PGPSLWEGTDSQQPHPRMKPSPLTPCPPGV 155
                    P P++ +    +   S     P P+  + T    P    +P+P TP  P  
Sbjct: 662 --------KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK---EPAPTTPKKPAP 710

Query: 156 PSP-SPPPHKLELQT 169
            +P +PPP   E+ T
Sbjct: 711 TTPETPPPTTSEVST 725



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 23/93 (24%), Positives = 34/93 (36%), Gaps = 6/93 (6%)

Query: 224 PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAP---APTPTPAPAAAPALTP 280
           P    KPK  A   +  + KP   +  P  P +   P T P    P  TP P    +  P
Sbjct: 867 PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 926

Query: 281 SSGPGSAALTLEEELQEAIRRAQLLPNRGIDDI 313
              P S    + E + +   R    PN  + ++
Sbjct: 927 ELNPTS---RIAEAMLQTTTRPNQTPNSKLVEV 956



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 34/157 (21%), Positives = 57/157 (36%), Gaps = 13/157 (8%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P       P     P+ T P   +P  L P     P   +  K +P   +    + P
Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 697

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPS-----LWEGTDSQQPHPRMKPSPL- 148
           +         P +P   +   P    S +  P  +     + +  D   P    +P+P  
Sbjct: 698 KEPAPT---TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754

Query: 149 ---TPCPPGVP-SPSPPPHKLELQTLKLEELTVSELR 181
              +P  PGVP + +P   K E+ T   ++ T  +LR
Sbjct: 755 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 791


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 71/341 (20%), Positives = 113/341 (33%), Gaps = 50/341 (14%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P  +    P  P  P+ T P    P    P+    P   +PK+ +P  +++   + P
Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKE---PAPTTPKEPAPTTTKKPAPTTP 512

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPG 154
           +      +  P  P++ +   P+     L P  P     T  ++P P   P  L P  P 
Sbjct: 513 K------EPAPTTPKETAPTTPKK----LTPTTPEKLAPTTPEKPAPTT-PEELAPTTPE 561

Query: 155 VPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKP 214
            P+P+ P              T  E          P +  +           P    PK 
Sbjct: 562 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-----------PAPTTPKE 610

Query: 215 RREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTP------GTAPAPTP 268
               +P G     LK  A    ++    + +  + + P     D P      GTAP    
Sbjct: 611 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670

Query: 269 TPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIP 328
            PAP       P++  G+A  TL+E        A   P +               L P  
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEP-------APTTPKK----------PAPKELAPTT 713

Query: 329 LDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDP 369
              P S     P+P +   ++  +   P+PT    P+P  P
Sbjct: 714 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 754



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 72/343 (20%), Positives = 119/343 (34%), Gaps = 48/343 (13%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P  +    P  P  P+ T     +P      P       +PK+ +P   ++   + P
Sbjct: 302 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT------TPKEPAPTTPKKPAPTTP 355

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRM--KPSPLTPCP 152
           +      +  P  P++ +   P+        P P     T  ++P P    KP+P TP  
Sbjct: 356 K------EPAPTTPKEPTPTTPKEPAPTTKEPAP-----TTPKEPAPTAPKKPAPTTPKE 404

Query: 153 PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
           P   +P  P       T K    T  +       +  P +  +            P+E P
Sbjct: 405 PAPTTPKEPAPT----TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-P 459

Query: 213 KPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAP 272
            P     PA        PK  A    +   KP+  + + P P     P  AP  T  PAP
Sbjct: 460 SPTTTKEPAPTT-----PKEPAPTTPK---KPAPTTPKEPAPTTPKEP--APTTTKKPAP 509

Query: 273 AAAPALTPSSGPGSAALTLEEELQEAI--RRAQLLPNRGIDDILED--QVEPDDPLPPIP 328
                  P++ P   A T  ++L      + A   P +      E+     P++P P  P
Sbjct: 510 TTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 568

Query: 329 LDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTD 371
            +         P+P +   ++  +   P+PT    P+P  P +
Sbjct: 569 EE---------PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 79/366 (21%), Positives = 127/366 (34%), Gaps = 40/366 (10%)

Query: 36  PDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYC--PPWRSPKKESPKISQRWRESK 93
           P P       P  P  P+ T P   +P    P P     P   +PKK +P   +    + 
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409

Query: 94  PR--GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEG----------TDSQQPHP 141
           P+     T  +  P  P++ +    ++  +    P P+  +           T +++P P
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469

Query: 142 RM--KPSPLTPCPPGV-----PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGT 194
               +P+P TP  P       P+P+ P       T K    T  E          P +  
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 529

Query: 195 K--SMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPP 252
           K      E++    P +  P    E +P     P                 P AA+   P
Sbjct: 530 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-----TPTTPEEPAPTTPKAAAPNTP 584

Query: 253 LPRAADTPGTAPAPTP--TPAPAAAPALTPSSGPGSAALTLEEELQEAIRR---AQLLPN 307
              A  TP   PAPT    PAP       P++  G+A  TL+E      ++    +L P 
Sbjct: 585 KEPAPTTP-KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643

Query: 308 RGIDDILE--DQVEPDDP---LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSS 362
              +      D+  P  P    P  P + P       P+P +   ++  +   P+PT   
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 702

Query: 363 SPSPRD 368
            P+P++
Sbjct: 703 KPAPKE 708



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 60/303 (19%), Positives = 102/303 (33%), Gaps = 31/303 (10%)

Query: 73  PPWRSPKKESPKISQRWRESKPRGNL-TYHQYMPPEPRQGSRADPQAEGSALGPPGPSLW 131
           P   +PK+ +P   +    + P+    T  +  P  P++ +    ++  +    P P   
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP--- 305

Query: 132 EGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPV 191
             T +++P P    +P  P P     P+P   K    T K    T  +       +    
Sbjct: 306 --TTTKEPAPT---TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 360

Query: 192 SGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRP 251
           +  K       +  AP  + P P     PA        PK           KP+  + + 
Sbjct: 361 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA-----PK-----------KPAPTTPKE 404

Query: 252 PLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGID 311
           P P     P       P+P     PA T +    SA  T +E      + A   P     
Sbjct: 405 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK---SAPTTTKEPAPTTTKSAPTTPKEPSP 461

Query: 312 DILEDQVE--PDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDP 369
              ++     P +P P  P   P       P+P +    +  ++  P+PT    P+P  P
Sbjct: 462 TTTKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 520

Query: 370 TDS 372
            ++
Sbjct: 521 KET 523



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 68/280 (24%), Positives = 96/280 (34%), Gaps = 57/280 (20%)

Query: 48  APALPSGTAPFLFSPGVLLPE-PEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPP 106
           AP  P  TAP   +P  L P  PE   P  +P+K +P   +    + P       +  P 
Sbjct: 516 APTTPKETAPT--TPKKLTPTTPEKLAP-TTPEKPAPTTPEELAPTTPE------EPTPT 566

Query: 107 EPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRM--KPSPLTP------CPPGV--- 155
            P + +   P+A      P  P     T  ++P P    +P+P TP       P G    
Sbjct: 567 TPEEPAPTTPKAAA----PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 622

Query: 156 ----PSPSPP----PHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAP 207
               P+P+ P    P +L   T K    T  +       +G   +  K           P
Sbjct: 623 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----------P 672

Query: 208 PRERPKPRREDSPAGAPWPRLK-----------PKALAAARRQGSVKPSAASHRPPLPR- 255
               PK     +P G     LK           PK LA    +G    ++    P  P+ 
Sbjct: 673 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 732

Query: 256 AADTPGTAPAPT--PTPAPAAAPALTPSSGPGSAALTLEE 293
            A T    PAPT    PAP       P++   S   T +E
Sbjct: 733 TAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 772



 Score = 36.2 bits (82), Expect = 0.056
 Identities = 62/319 (19%), Positives = 101/319 (31%), Gaps = 53/319 (16%)

Query: 136 SQQPHPRMKPSP-LTPCPPGVPSPSPPPHKLELQ----------TLKLEELTVSELRQQL 184
           S   H ++  SP +T   P  P PS PP+    +          T++ +E T +  +   
Sbjct: 146 STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTST 205

Query: 185 RLRGLPVSGTKSMLLERMRGG--APPRE---RPKPRREDSPAGAPWPRLKPKALAAARRQ 239
             +    S  ++  +E+      AP  +   +P P+ E +  G      K       +  
Sbjct: 206 DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 265

Query: 240 GSVKPSAASHRPPLPRAADTPGTAPAPTPT---------PAPAAAPALTPSSGPGSAALT 290
            S  P   +  P   ++A T    PAPT T         PAP       P++    A  T
Sbjct: 266 ASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 323

Query: 291 LEEELQEAIRRAQLLPNRGIDDILEDQVE----------PDDPLPPIPLD---------- 330
            +E      + A   P        +              P +P P  P +          
Sbjct: 324 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383

Query: 331 ----FPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLG 386
                P       P+P +    +  +   P+PT +  PSP  P +           P   
Sbjct: 384 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP--TTTKSAPTTT 441

Query: 387 SGPPPPSIFSADLSDSSSS 405
             P P +  SA  +    S
Sbjct: 442 KEPAPTTTKSAPTTPKEPS 460



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 17/135 (12%)

Query: 37  DPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRG 96
           +P  +  D P AP  P GTAP   +P    P     P   +PK  +P   +    + P+ 
Sbjct: 647 EPTSTTCDKP-APTTPKGTAPT--TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK- 702

Query: 97  NLTYHQYMPPEPRQGSRADPQAEGSALGP-PGPSLWEGTDSQQPHPRMKPSPLTPCPPGV 155
                    P P++ +    +   S     P P+  + T    P    +P+P TP  P  
Sbjct: 703 --------KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK---EPAPTTPKKPAP 751

Query: 156 PSP-SPPPHKLELQT 169
            +P +PPP   E+ T
Sbjct: 752 TTPETPPPTTSEVST 766



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 23/93 (24%), Positives = 34/93 (36%), Gaps = 6/93 (6%)

Query: 224 PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAP---APTPTPAPAAAPALTP 280
           P    KPK  A   +  + KP   +  P  P +   P T P    P  TP P    +  P
Sbjct: 908 PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 967

Query: 281 SSGPGSAALTLEEELQEAIRRAQLLPNRGIDDI 313
              P S    + E + +   R    PN  + ++
Sbjct: 968 ELNPTS---RIAEAMLQTTTRPNQTPNSKLVEV 997



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 34/157 (21%), Positives = 57/157 (36%), Gaps = 13/157 (8%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P       P     P+ T P   +P  L P     P   +  K +P   +    + P
Sbjct: 679 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 738

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPS-----LWEGTDSQQPHPRMKPSPL- 148
           +         P +P   +   P    S +  P  +     + +  D   P    +P+P  
Sbjct: 739 KEPAPT---TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795

Query: 149 ---TPCPPGVP-SPSPPPHKLELQTLKLEELTVSELR 181
              +P  PGVP + +P   K E+ T   ++ T  +LR
Sbjct: 796 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 832


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 71/341 (20%), Positives = 113/341 (33%), Gaps = 50/341 (14%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P  +    P  P  P+ T P    P    P+    P   +PK+ +P  +++   + P
Sbjct: 510 EPSPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKE---PAPTTPKEPAPTTTKKPAPTTP 564

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPG 154
           +      +  P  P++ +   P+     L P  P     T  ++P P   P  L P  P 
Sbjct: 565 K------EPAPTTPKETAPTTPKK----LTPTTPEKLAPTTPEKPAPTT-PEELAPTTPE 613

Query: 155 VPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKP 214
            P+P+ P              T  E          P +  +           P    PK 
Sbjct: 614 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-----------PAPTTPKE 662

Query: 215 RREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTP------GTAPAPTP 268
               +P G     LK  A    ++    + +  + + P     D P      GTAP    
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 722

Query: 269 TPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIP 328
            PAP       P++  G+A  TL+E        A   P +               L P  
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEP-------APTTPKK----------PAPKELAPTT 765

Query: 329 LDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDP 369
              P S     P+P +   ++  +   P+PT    P+P  P
Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 806



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 72/343 (20%), Positives = 119/343 (34%), Gaps = 48/343 (13%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P  +    P  P  P+ T     +P      P       +PK+ +P   ++   + P
Sbjct: 354 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT------TPKEPAPTTPKKPAPTTP 407

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRM--KPSPLTPCP 152
           +      +  P  P++ +   P+        P P     T  ++P P    KP+P TP  
Sbjct: 408 K------EPAPTTPKEPTPTTPKEPAPTTKEPAP-----TTPKEPAPTAPKKPAPTTPKE 456

Query: 153 PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
           P   +P  P       T K    T  +       +  P +  +            P+E P
Sbjct: 457 PAPTTPKEPAPT----TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-P 511

Query: 213 KPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAP 272
            P     PA        PK  A    +   KP+  + + P P     P  AP  T  PAP
Sbjct: 512 SPTTTKEPAPTT-----PKEPAPTTPK---KPAPTTPKEPAPTTPKEP--APTTTKKPAP 561

Query: 273 AAAPALTPSSGPGSAALTLEEELQEAI--RRAQLLPNRGIDDILED--QVEPDDPLPPIP 328
                  P++ P   A T  ++L      + A   P +      E+     P++P P  P
Sbjct: 562 TTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620

Query: 329 LDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTD 371
            +         P+P +   ++  +   P+PT    P+P  P +
Sbjct: 621 EE---------PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 79/366 (21%), Positives = 127/366 (34%), Gaps = 40/366 (10%)

Query: 36  PDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYC--PPWRSPKKESPKISQRWRESK 93
           P P       P  P  P+ T P   +P    P P     P   +PKK +P   +    + 
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461

Query: 94  PR--GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEG----------TDSQQPHP 141
           P+     T  +  P  P++ +    ++  +    P P+  +           T +++P P
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521

Query: 142 RM--KPSPLTPCPPGV-----PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGT 194
               +P+P TP  P       P+P+ P       T K    T  E          P +  
Sbjct: 522 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 581

Query: 195 K--SMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPP 252
           K      E++    P +  P    E +P     P                 P AA+   P
Sbjct: 582 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-----TPTTPEEPAPTTPKAAAPNTP 636

Query: 253 LPRAADTPGTAPAPTP--TPAPAAAPALTPSSGPGSAALTLEEELQEAIRR---AQLLPN 307
              A  TP   PAPT    PAP       P++  G+A  TL+E      ++    +L P 
Sbjct: 637 KEPAPTTP-KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695

Query: 308 RGIDDILE--DQVEPDDP---LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSS 362
              +      D+  P  P    P  P + P       P+P +   ++  +   P+PT   
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 754

Query: 363 SPSPRD 368
            P+P++
Sbjct: 755 KPAPKE 760



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 60/303 (19%), Positives = 102/303 (33%), Gaps = 31/303 (10%)

Query: 73  PPWRSPKKESPKISQRWRESKPRGNL-TYHQYMPPEPRQGSRADPQAEGSALGPPGPSLW 131
           P   +PK+ +P   +    + P+    T  +  P  P++ +    ++  +    P P   
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP--- 357

Query: 132 EGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPV 191
             T +++P P    +P  P P     P+P   K    T K    T  +       +    
Sbjct: 358 --TTTKEPAPT---TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412

Query: 192 SGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRP 251
           +  K       +  AP  + P P     PA        PK           KP+  + + 
Sbjct: 413 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA-----PK-----------KPAPTTPKE 456

Query: 252 PLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGID 311
           P P     P       P+P     PA T +    SA  T +E      + A   P     
Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK---SAPTTTKEPAPTTTKSAPTTPKEPSP 513

Query: 312 DILEDQVE--PDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDP 369
              ++     P +P P  P   P       P+P +    +  ++  P+PT    P+P  P
Sbjct: 514 TTTKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572

Query: 370 TDS 372
            ++
Sbjct: 573 KET 575



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 68/280 (24%), Positives = 96/280 (34%), Gaps = 57/280 (20%)

Query: 48  APALPSGTAPFLFSPGVLLPE-PEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPP 106
           AP  P  TAP   +P  L P  PE   P  +P+K +P   +    + P       +  P 
Sbjct: 568 APTTPKETAPT--TPKKLTPTTPEKLAP-TTPEKPAPTTPEELAPTTPE------EPTPT 618

Query: 107 EPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRM--KPSPLTP------CPPGV--- 155
            P + +   P+A      P  P     T  ++P P    +P+P TP       P G    
Sbjct: 619 TPEEPAPTTPKAAA----PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 674

Query: 156 ----PSPSPP----PHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAP 207
               P+P+ P    P +L   T K    T  +       +G   +  K           P
Sbjct: 675 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----------P 724

Query: 208 PRERPKPRREDSPAGAPWPRLK-----------PKALAAARRQGSVKPSAASHRPPLPR- 255
               PK     +P G     LK           PK LA    +G    ++    P  P+ 
Sbjct: 725 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 784

Query: 256 AADTPGTAPAPT--PTPAPAAAPALTPSSGPGSAALTLEE 293
            A T    PAPT    PAP       P++   S   T +E
Sbjct: 785 TAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 824



 Score = 36.2 bits (82), Expect = 0.056
 Identities = 62/319 (19%), Positives = 101/319 (31%), Gaps = 53/319 (16%)

Query: 136 SQQPHPRMKPSP-LTPCPPGVPSPSPPPHKLELQ----------TLKLEELTVSELRQQL 184
           S   H ++  SP +T   P  P PS PP+    +          T++ +E T +  +   
Sbjct: 198 STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTST 257

Query: 185 RLRGLPVSGTKSMLLERMRGG--APPRE---RPKPRREDSPAGAPWPRLKPKALAAARRQ 239
             +    S  ++  +E+      AP  +   +P P+ E +  G      K       +  
Sbjct: 258 DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 317

Query: 240 GSVKPSAASHRPPLPRAADTPGTAPAPTPT---------PAPAAAPALTPSSGPGSAALT 290
            S  P   +  P   ++A T    PAPT T         PAP       P++    A  T
Sbjct: 318 ASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 375

Query: 291 LEEELQEAIRRAQLLPNRGIDDILEDQVE----------PDDPLPPIPLD---------- 330
            +E      + A   P        +              P +P P  P +          
Sbjct: 376 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435

Query: 331 ----FPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLG 386
                P       P+P +    +  +   P+PT +  PSP  P +           P   
Sbjct: 436 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP--TTTKSAPTTT 493

Query: 387 SGPPPPSIFSADLSDSSSS 405
             P P +  SA  +    S
Sbjct: 494 KEPAPTTTKSAPTTPKEPS 512



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 17/135 (12%)

Query: 37  DPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRG 96
           +P  +  D P AP  P GTAP   +P    P     P   +PK  +P   +    + P+ 
Sbjct: 699 EPTSTTCDKP-APTTPKGTAPT--TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK- 754

Query: 97  NLTYHQYMPPEPRQGSRADPQAEGSALGP-PGPSLWEGTDSQQPHPRMKPSPLTPCPPGV 155
                    P P++ +    +   S     P P+  + T    P    +P+P TP  P  
Sbjct: 755 --------KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK---EPAPTTPKKPAP 803

Query: 156 PSP-SPPPHKLELQT 169
            +P +PPP   E+ T
Sbjct: 804 TTPETPPPTTSEVST 818



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 23/93 (24%), Positives = 34/93 (36%), Gaps = 6/93 (6%)

Query: 224  PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAP---APTPTPAPAAAPALTP 280
            P    KPK  A   +  + KP   +  P  P +   P T P    P  TP P    +  P
Sbjct: 960  PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1019

Query: 281  SSGPGSAALTLEEELQEAIRRAQLLPNRGIDDI 313
               P S    + E + +   R    PN  + ++
Sbjct: 1020 ELNPTS---RIAEAMLQTTTRPNQTPNSKLVEV 1049



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 34/157 (21%), Positives = 57/157 (36%), Gaps = 13/157 (8%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P       P     P+ T P   +P  L P     P   +  K +P   +    + P
Sbjct: 731 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPS-----LWEGTDSQQPHPRMKPSPL- 148
           +         P +P   +   P    S +  P  +     + +  D   P    +P+P  
Sbjct: 791 KEPAPT---TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847

Query: 149 ---TPCPPGVP-SPSPPPHKLELQTLKLEELTVSELR 181
              +P  PGVP + +P   K E+ T   ++ T  +LR
Sbjct: 848 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 884


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 71/341 (20%), Positives = 113/341 (33%), Gaps = 50/341 (14%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P  +    P  P  P+ T P    P    P+    P   +PK+ +P  +++   + P
Sbjct: 551 EPSPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKE---PAPTTPKEPAPTTTKKPAPTTP 605

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPG 154
           +      +  P  P++ +   P+     L P  P     T  ++P P   P  L P  P 
Sbjct: 606 K------EPAPTTPKETAPTTPKK----LTPTTPEKLAPTTPEKPAPTT-PEELAPTTPE 654

Query: 155 VPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKP 214
            P+P+ P              T  E          P +  +           P    PK 
Sbjct: 655 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-----------PAPTTPKE 703

Query: 215 RREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTP------GTAPAPTP 268
               +P G     LK  A    ++    + +  + + P     D P      GTAP    
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 763

Query: 269 TPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIP 328
            PAP       P++  G+A  TL+E        A   P +               L P  
Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEP-------APTTPKK----------PAPKELAPTT 806

Query: 329 LDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDP 369
              P S     P+P +   ++  +   P+PT    P+P  P
Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 847



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 72/343 (20%), Positives = 119/343 (34%), Gaps = 48/343 (13%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P  +    P  P  P+ T     +P      P       +PK+ +P   ++   + P
Sbjct: 395 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT------TPKEPAPTTPKKPAPTTP 448

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRM--KPSPLTPCP 152
           +      +  P  P++ +   P+        P P     T  ++P P    KP+P TP  
Sbjct: 449 K------EPAPTTPKEPTPTTPKEPAPTTKEPAP-----TTPKEPAPTAPKKPAPTTPKE 497

Query: 153 PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
           P   +P  P       T K    T  +       +  P +  +            P+E P
Sbjct: 498 PAPTTPKEPAPT----TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-P 552

Query: 213 KPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAP 272
            P     PA        PK  A    +   KP+  + + P P     P  AP  T  PAP
Sbjct: 553 SPTTTKEPAPTT-----PKEPAPTTPK---KPAPTTPKEPAPTTPKEP--APTTTKKPAP 602

Query: 273 AAAPALTPSSGPGSAALTLEEELQEAI--RRAQLLPNRGIDDILED--QVEPDDPLPPIP 328
                  P++ P   A T  ++L      + A   P +      E+     P++P P  P
Sbjct: 603 TTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661

Query: 329 LDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTD 371
            +         P+P +   ++  +   P+PT    P+P  P +
Sbjct: 662 EE---------PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 79/366 (21%), Positives = 127/366 (34%), Gaps = 40/366 (10%)

Query: 36  PDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYC--PPWRSPKKESPKISQRWRESK 93
           P P       P  P  P+ T P   +P    P P     P   +PKK +P   +    + 
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502

Query: 94  PR--GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEG----------TDSQQPHP 141
           P+     T  +  P  P++ +    ++  +    P P+  +           T +++P P
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562

Query: 142 RM--KPSPLTPCPPGV-----PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGT 194
               +P+P TP  P       P+P+ P       T K    T  E          P +  
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 622

Query: 195 K--SMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPP 252
           K      E++    P +  P    E +P     P                 P AA+   P
Sbjct: 623 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-----TPTTPEEPAPTTPKAAAPNTP 677

Query: 253 LPRAADTPGTAPAPTP--TPAPAAAPALTPSSGPGSAALTLEEELQEAIRR---AQLLPN 307
              A  TP   PAPT    PAP       P++  G+A  TL+E      ++    +L P 
Sbjct: 678 KEPAPTTP-KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736

Query: 308 RGIDDILE--DQVEPDDP---LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSS 362
              +      D+  P  P    P  P + P       P+P +   ++  +   P+PT   
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 795

Query: 363 SPSPRD 368
            P+P++
Sbjct: 796 KPAPKE 801



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 60/303 (19%), Positives = 102/303 (33%), Gaps = 31/303 (10%)

Query: 73  PPWRSPKKESPKISQRWRESKPRGNL-TYHQYMPPEPRQGSRADPQAEGSALGPPGPSLW 131
           P   +PK+ +P   +    + P+    T  +  P  P++ +    ++  +    P P   
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP--- 398

Query: 132 EGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPV 191
             T +++P P    +P  P P     P+P   K    T K    T  +       +    
Sbjct: 399 --TTTKEPAPT---TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453

Query: 192 SGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRP 251
           +  K       +  AP  + P P     PA        PK           KP+  + + 
Sbjct: 454 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA-----PK-----------KPAPTTPKE 497

Query: 252 PLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGID 311
           P P     P       P+P     PA T +    SA  T +E      + A   P     
Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK---SAPTTTKEPAPTTTKSAPTTPKEPSP 554

Query: 312 DILEDQVE--PDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDP 369
              ++     P +P P  P   P       P+P +    +  ++  P+PT    P+P  P
Sbjct: 555 TTTKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613

Query: 370 TDS 372
            ++
Sbjct: 614 KET 616



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 68/280 (24%), Positives = 96/280 (34%), Gaps = 57/280 (20%)

Query: 48  APALPSGTAPFLFSPGVLLPE-PEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPP 106
           AP  P  TAP   +P  L P  PE   P  +P+K +P   +    + P       +  P 
Sbjct: 609 APTTPKETAPT--TPKKLTPTTPEKLAP-TTPEKPAPTTPEELAPTTPE------EPTPT 659

Query: 107 EPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRM--KPSPLTP------CPPGV--- 155
            P + +   P+A      P  P     T  ++P P    +P+P TP       P G    
Sbjct: 660 TPEEPAPTTPKAAA----PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 715

Query: 156 ----PSPSPP----PHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAP 207
               P+P+ P    P +L   T K    T  +       +G   +  K           P
Sbjct: 716 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----------P 765

Query: 208 PRERPKPRREDSPAGAPWPRLK-----------PKALAAARRQGSVKPSAASHRPPLPR- 255
               PK     +P G     LK           PK LA    +G    ++    P  P+ 
Sbjct: 766 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 825

Query: 256 AADTPGTAPAPT--PTPAPAAAPALTPSSGPGSAALTLEE 293
            A T    PAPT    PAP       P++   S   T +E
Sbjct: 826 TAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 865



 Score = 36.2 bits (82), Expect = 0.056
 Identities = 62/319 (19%), Positives = 101/319 (31%), Gaps = 53/319 (16%)

Query: 136 SQQPHPRMKPSP-LTPCPPGVPSPSPPPHKLELQ----------TLKLEELTVSELRQQL 184
           S   H ++  SP +T   P  P PS PP+    +          T++ +E T +  +   
Sbjct: 239 STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTST 298

Query: 185 RLRGLPVSGTKSMLLERMRGG--APPRE---RPKPRREDSPAGAPWPRLKPKALAAARRQ 239
             +    S  ++  +E+      AP  +   +P P+ E +  G      K       +  
Sbjct: 299 DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 358

Query: 240 GSVKPSAASHRPPLPRAADTPGTAPAPTPT---------PAPAAAPALTPSSGPGSAALT 290
            S  P   +  P   ++A T    PAPT T         PAP       P++    A  T
Sbjct: 359 ASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 416

Query: 291 LEEELQEAIRRAQLLPNRGIDDILEDQVE----------PDDPLPPIPLD---------- 330
            +E      + A   P        +              P +P P  P +          
Sbjct: 417 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476

Query: 331 ----FPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLG 386
                P       P+P +    +  +   P+PT +  PSP  P +           P   
Sbjct: 477 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP--TTTKSAPTTT 534

Query: 387 SGPPPPSIFSADLSDSSSS 405
             P P +  SA  +    S
Sbjct: 535 KEPAPTTTKSAPTTPKEPS 553



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 17/135 (12%)

Query: 37  DPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRG 96
           +P  +  D P AP  P GTAP   +P    P     P   +PK  +P   +    + P+ 
Sbjct: 740 EPTSTTCDKP-APTTPKGTAPT--TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK- 795

Query: 97  NLTYHQYMPPEPRQGSRADPQAEGSALGP-PGPSLWEGTDSQQPHPRMKPSPLTPCPPGV 155
                    P P++ +    +   S     P P+  + T    P    +P+P TP  P  
Sbjct: 796 --------KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK---EPAPTTPKKPAP 844

Query: 156 PSP-SPPPHKLELQT 169
            +P +PPP   E+ T
Sbjct: 845 TTPETPPPTTSEVST 859



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 23/93 (24%), Positives = 34/93 (36%), Gaps = 6/93 (6%)

Query: 224  PWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAP---APTPTPAPAAAPALTP 280
            P    KPK  A   +  + KP   +  P  P +   P T P    P  TP P    +  P
Sbjct: 1001 PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1060

Query: 281  SSGPGSAALTLEEELQEAIRRAQLLPNRGIDDI 313
               P S    + E + +   R    PN  + ++
Sbjct: 1061 ELNPTS---RIAEAMLQTTTRPNQTPNSKLVEV 1090



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 34/157 (21%), Positives = 57/157 (36%), Gaps = 13/157 (8%)

Query: 35  DPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
           +P P       P     P+ T P   +P  L P     P   +  K +P   +    + P
Sbjct: 772 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPS-----LWEGTDSQQPHPRMKPSPL- 148
           +         P +P   +   P    S +  P  +     + +  D   P    +P+P  
Sbjct: 832 KEPAPT---TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888

Query: 149 ---TPCPPGVP-SPSPPPHKLELQTLKLEELTVSELR 181
              +P  PGVP + +P   K E+ T   ++ T  +LR
Sbjct: 889 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 925


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 77/296 (26%), Positives = 114/296 (38%), Gaps = 37/296 (12%)

Query: 47  LAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESP-------KISQR-WRESKPR--- 95
           L  A PSGT P  + P   +P P   P  R   ++ P       K+    W     R   
Sbjct: 333 LGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAML 392

Query: 96  -GNLTYHQYMPP--EPRQGSRADPQAEGSALGPPGPSLWEGTDSQQP-HPRMKPSPLTPC 151
            G+  + +  PP  +P+   +  PQ++     PP P     T +  P HP+    P+   
Sbjct: 393 PGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEG 452

Query: 152 PPGVPSPSPPPHKLE------LQTLKLEELTVSELRQQLRLR-GLPVSGTKSMLLERMRG 204
           PP  P+   P  ++E      L+   ++E  V+      RL+  LP        LE +  
Sbjct: 453 PPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVAR 512

Query: 205 GAPPRERPKPRR---EDSPAGAPWPRLKPK----ALAAARRQGSVKPSAAS-HRPPLPRA 256
                 RP  RR   E +PA A  P  K +          R G   P        P+   
Sbjct: 513 VLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEG 572

Query: 257 ADTPGTAPAPTPTPAPAAAPALTPSSGPGS-AALTLEEELQEA-----IRRAQLLP 306
           ++     PAP P PAP   PA + SS P    ++ +   L++A      RRA+L P
Sbjct: 573 SEARAGPPAPAP-PAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNP 627



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 82/334 (24%), Positives = 115/334 (34%), Gaps = 67/334 (20%)

Query: 89  WRESKPRG-------NLTY----HQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGT--D 135
           WRES   G       NLT       Y         R+D  +   +LG  GPS   GT   
Sbjct: 288 WRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPS---GTLPR 344

Query: 136 SQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTK 195
           S QP  R+   P +P P G P   P P  +     KL+         +  L G P+    
Sbjct: 345 SWQPVSRIPMPPSSPQPRGAPRQRPIPLSM---IFKLQNAFWEHGASRAMLPGSPL---- 397

Query: 196 SMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPR 255
                      PP+ +P+P+ +  P   P P+L P        Q   +P   +  P  P+
Sbjct: 398 ------FTRAPPPKLQPQPQPQPQPQSQPQPQLPP--------QPQTQPQTPTPAPQHPQ 443

Query: 256 AADTPGTAPAPTP----TPAPAAAPALTP-------SSGPGSAALTLEEELQEAI-RRAQ 303
               P     P P     P P     LTP         GP +  L+    LQ A+   AQ
Sbjct: 444 QTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLS-PTRLQPALPPEAQ 502

Query: 304 LLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFD----VLSPSPDSEGLSSVFSSSLPSPT 359
            +P   ++++     E      P PL   GS +    V  P    +    + S       
Sbjct: 503 SVPE--LEEVARVLAE-----IPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLF---H 552

Query: 360 NSSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPS 393
               P P  P      L  ++ G    +GPP P+
Sbjct: 553 RHGGPGPGGPEPE---LSPITEGSEARAGPPAPA 583



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 51/186 (27%), Positives = 64/186 (34%), Gaps = 26/186 (13%)

Query: 218 DSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRA---ADTPGTAPAPTPTPAPAA 274
           DSPA  P P+  P +        S+     S   P   A   ADTP       PT  P +
Sbjct: 52  DSPA-PPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYS 110

Query: 275 APALTPSSGPGS--AALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLP------- 325
              L+P   P S    L L+ +   ++ RA     R  D           P P       
Sbjct: 111 P--LSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQ 168

Query: 326 ---PIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGG 382
              P P DF G       SP +EG  + F            PSPR P  + D   +  G 
Sbjct: 169 QGPPTPFDFLGRAGSPRGSPLAEGPQAFFP--------ERGPSPRPPATAYDAPASAFGS 220

Query: 383 PPLGSG 388
             LGSG
Sbjct: 221 SLLGSG 226


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 77/296 (26%), Positives = 114/296 (38%), Gaps = 37/296 (12%)

Query: 47  LAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESP-------KISQR-WRESKPR--- 95
           L  A PSGT P  + P   +P P   P  R   ++ P       K+    W     R   
Sbjct: 333 LGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAML 392

Query: 96  -GNLTYHQYMPP--EPRQGSRADPQAEGSALGPPGPSLWEGTDSQQP-HPRMKPSPLTPC 151
            G+  + +  PP  +P+   +  PQ++     PP P     T +  P HP+    P+   
Sbjct: 393 PGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEG 452

Query: 152 PPGVPSPSPPPHKLE------LQTLKLEELTVSELRQQLRLR-GLPVSGTKSMLLERMRG 204
           PP  P+   P  ++E      L+   ++E  V+      RL+  LP        LE +  
Sbjct: 453 PPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVAR 512

Query: 205 GAPPRERPKPRR---EDSPAGAPWPRLKPK----ALAAARRQGSVKPSAAS-HRPPLPRA 256
                 RP  RR   E +PA A  P  K +          R G   P        P+   
Sbjct: 513 VLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEG 572

Query: 257 ADTPGTAPAPTPTPAPAAAPALTPSSGPGS-AALTLEEELQEA-----IRRAQLLP 306
           ++     PAP P PAP   PA + SS P    ++ +   L++A      RRA+L P
Sbjct: 573 SEARAGPPAPAP-PAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNP 627



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 82/334 (24%), Positives = 115/334 (34%), Gaps = 67/334 (20%)

Query: 89  WRESKPRG-------NLTY----HQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGT--D 135
           WRES   G       NLT       Y         R+D  +   +LG  GPS   GT   
Sbjct: 288 WRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPS---GTLPR 344

Query: 136 SQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTK 195
           S QP  R+   P +P P G P   P P  +     KL+         +  L G P+    
Sbjct: 345 SWQPVSRIPMPPSSPQPRGAPRQRPIPLSM---IFKLQNAFWEHGASRAMLPGSPL---- 397

Query: 196 SMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPR 255
                      PP+ +P+P+ +  P   P P+L P        Q   +P   +  P  P+
Sbjct: 398 ------FTRAPPPKLQPQPQPQPQPQSQPQPQLPP--------QPQTQPQTPTPAPQHPQ 443

Query: 256 AADTPGTAPAPTP----TPAPAAAPALTP-------SSGPGSAALTLEEELQEAI-RRAQ 303
               P     P P     P P     LTP         GP +  L+    LQ A+   AQ
Sbjct: 444 QTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLS-PTRLQPALPPEAQ 502

Query: 304 LLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFD----VLSPSPDSEGLSSVFSSSLPSPT 359
            +P   ++++     E      P PL   GS +    V  P    +    + S       
Sbjct: 503 SVPE--LEEVARVLAE-----IPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLF---H 552

Query: 360 NSSSPSPRDPTDSLDWLEALSGGPPLGSGPPPPS 393
               P P  P      L  ++ G    +GPP P+
Sbjct: 553 RHGGPGPGGPEPE---LSPITEGSEARAGPPAPA 583



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 51/186 (27%), Positives = 64/186 (34%), Gaps = 26/186 (13%)

Query: 218 DSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRA---ADTPGTAPAPTPTPAPAA 274
           DSPA  P P+  P +        S+     S   P   A   ADTP       PT  P +
Sbjct: 52  DSPA-PPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYS 110

Query: 275 APALTPSSGPGS--AALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLP------- 325
              L+P   P S    L L+ +   ++ RA     R  D           P P       
Sbjct: 111 P--LSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQ 168

Query: 326 ---PIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGG 382
              P P DF G       SP +EG  + F            PSPR P  + D   +  G 
Sbjct: 169 QGPPTPFDFLGRAGSPRGSPLAEGPQAFFP--------ERGPSPRPPATAYDAPASAFGS 220

Query: 383 PPLGSG 388
             LGSG
Sbjct: 221 SLLGSG 226


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 105/398 (26%), Positives = 130/398 (32%), Gaps = 54/398 (13%)

Query: 41  SASDPPLAPALPSGTAP----FLFSPGVLLPEPEYCP---PWRSPKKESPKISQRWRESK 93
           SA   P APA PS   P     L  P V  P  +  P   P  S    +P  S   +   
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQA 317

Query: 94  PRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLT---- 149
           P         +P  P   S     A    L PP PS      +    P   PS  T    
Sbjct: 318 P-------PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG 370

Query: 150 -----------PCPPGVPSPSPPPHKLELQTLK-LEELTVSELRQQLRLRGLPVSGTKSM 197
                      P PP  P  +PPP       L  L+          L     P     + 
Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430

Query: 198 LLERMRGGAPPRERPKPRREDSPAGAPW-PRLKPKALAAARRQGSVKPSAASHRPPL--- 253
           L   +   AP    P P     P  AP+ P   P    +A       PS A+  PPL   
Sbjct: 431 LAVHLLQ-APFSPPPSP-----PVQAPFSPPASPPVSPSATPPSQAPPSLAA--PPLQVP 482

Query: 254 PRAADTPGTAPAPTP---TPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGI 310
           P    +P  +P+ TP    P P AAP L  +  P  A   L      A    Q LP+   
Sbjct: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL------ATPPLQALPSPPA 536

Query: 311 DDILEDQVEPDDPLPPIPLDF--PGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRD 368
               +    P   LP  PL    P +  VL+        S   S +L +P    +P P  
Sbjct: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596

Query: 369 PTDSLDWLEALSGGPPLGSGPPPPSIFSA-DLSDSSSS 405
                    AL+ GPP      P S  S  DL+  SSS
Sbjct: 597 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 101/418 (24%), Positives = 137/418 (32%), Gaps = 66/418 (15%)

Query: 42  ASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKE------SPKISQRWRESKPR 95
           A++ P   AL +G       P    P P      R+   E      +P    R     PR
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206

Query: 96  GNLTY-HQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPS----PLTP 150
            +++   ++   EP   +R  P A G    P   SL           R  PS    P  P
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 151 CPPGVPSPS----------PPPHKLE------LQTLKLEELTVSELRQQLRLRGLPVSGT 194
             P  P P            PP K        L +  L   + S   Q      LP +  
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326

Query: 195 KSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVK---PSAASHRP 251
            S L  ++         P P    SP+  P  +  P   A    Q +     P+  +   
Sbjct: 327 SSSLTCQLA-------TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 379

Query: 252 PLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGID 311
            LP    +P   P P   PA A  P   P S P S  L+           +   PN    
Sbjct: 380 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS------PLATPSPQAPNALAV 433

Query: 312 DILEDQVEPDDPLPPIPLDF-PGSFDVLSPS--PDSEGLSSVFSSSL---PSPTNSS--S 363
            +L+    P  P PP+   F P +   +SPS  P S+   S+ +  L   PSP  S   S
Sbjct: 434 HLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492

Query: 364 PSPRDPTDSLDWLEA--------------LSGGPPLGSGPPPPSIFSADLSDSSSSRL 407
           PS   P  +   L A                  PPL + P PP+ F      S S+ L
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 88/350 (25%), Positives = 119/350 (34%), Gaps = 60/350 (17%)

Query: 43  SDPPLAP-ALPSGTAP------FLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           + PPL+P A PS  AP       L +P    P P    P+  P       S       P 
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472

Query: 96  GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGV 155
                   +PP P       P A      PP P         +P P+  P+  TP    +
Sbjct: 473 SLAAPPLQVPPSPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPLQAL 531

Query: 156 PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPR 215
           PSP   P     Q                     P S + S+ +  +    PP + P   
Sbjct: 532 PSP---PASFPGQA--------------------PFSPSASLPMSPL--ATPPPQAPPVL 566

Query: 216 REDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAA 275
                   P P   P  L A RR  +  P  +   P L  A   PG  P P P+ +P++ 
Sbjct: 567 AAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLAL-APG--PPPPPSRSPSST 622

Query: 276 PALTPSSGPGSAALTLEEELQ------EAIRRAQLLP------------NRGIDDILEDQ 317
            +    +G  S+A +  EEL+      E    A   P            +RG    L  +
Sbjct: 623 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 682

Query: 318 VEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSP-TNSSSPSP 366
             P  PLP  P   PGS D L    ++EG      S+ P+P      PSP
Sbjct: 683 GAPGAPLPWPPATGPGSADGLCTIYETEGP----ESATPAPGALDPGPSP 728



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 90/373 (24%), Positives = 130/373 (34%), Gaps = 54/373 (14%)

Query: 48  APALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPPE 107
           A A  +   P   +PG+L P P       SP+   P      R     G +         
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62

Query: 108 PRQGSRADPQAEGSALGPPGPSLWEGTDSQQP-------------HPRMKPSPLTPCPPG 154
              G    P++   A    GP+   GT S+ P              P    SP     PG
Sbjct: 63  GGIGGATIPESAPRA----GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118

Query: 155 VPSPSPPPHKLELQTLKLE--------ELTVSELRQQL-----RLRGLPVSGTKSMLLER 201
             S +  P  L  + L++         + T +  R  L     R    P  GT S  + R
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178

Query: 202 MRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPP-----LPR- 255
            R  A   E   PR   S    P      K++++A    + +PS A+ R P     L R 
Sbjct: 179 -RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237

Query: 256 AADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILE 315
           A+ +  ++  P  +PA +   A      P   +    + LQ A+R  Q+ P R      +
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ-ALRPPQVTPPR------K 290

Query: 316 DQVEPDDPLPPIPLDFPGSFDVLS----PSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTD 371
           D      PL   PL  P     L     P+  +   SS  +  L +P   + PSP  P  
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP-P 349

Query: 372 SLDWLEALSGGPP 384
           SL  L +    PP
Sbjct: 350 SLQTLPSPPATPP 362



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 70/277 (25%), Positives = 90/277 (32%), Gaps = 54/277 (19%)

Query: 38  PWISASDPPLAPAL--PSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           P+   + PP++P+   PS   P L +P + +P      P  SP    P            
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP----------- 499

Query: 96  GNLTYHQYMPP---EPRQGSRADPQAEGSALGPP------GPSLWEGTDSQQPHPRMKPS 146
                 Q  PP    P Q ++  PQA  +   PP       P+ + G     P   +  S
Sbjct: 500 ------QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 553

Query: 147 PLTPCPPGVPS---------PSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSM 197
           PL   PP  P          P  PP    LQ  +         R         VSG + +
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR---------RPPTPGPDTSVSGPR-L 603

Query: 198 LLERMRGGAPPRERPKPRREDSP--AGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPR 255
            L    G  PP  R        P  AG                 G    +AAS  P    
Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 663

Query: 256 AADTP-----GTAPAPTPTPAPAAAPALTPSSGPGSA 287
           AA  P     G AP      AP A     P++GPGSA
Sbjct: 664 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 700


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 100/399 (25%), Positives = 135/399 (33%), Gaps = 58/399 (14%)

Query: 42  ASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKE------SPKISQRWRESKPR 95
           A++ P   AL +G       P    P P      R+   E      +P    R     PR
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197

Query: 96  GNLTY-HQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPL-TPCPP 153
            +++   ++   EP   +R  P A G    P   SL           R  PS   TP  P
Sbjct: 198 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257

Query: 154 GVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPK 213
             PS   P     LQ L+  ++T        R    P  G  S         + P   P 
Sbjct: 258 AHPSQPKPKG---LQALRPPQVTPP------RKDAAPALGPLS---------SSPLATPS 299

Query: 214 PRREDSPAGAPWPRLKPKALAAARRQGSVK---PSAASHRPPLPRAADTPGTAPAPTPTP 270
           P    SP+  P  +  P   A    Q +     P+  +    LP    +P   P P   P
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359

Query: 271 APAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLD 330
           A A  P   P S P S  L+           +   PN     +L+    P  P PP+   
Sbjct: 360 ALALPPLQAPPSPPASPPLS------PLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAP 412

Query: 331 F-PGSFDVLSPS--PDSEGLSSVFSSSL---PSPTNSS--SPSPRDPTDSLDWLEA---- 378
           F P +   +SPS  P S+   S+ +  L   PSP  S   SPS   P  +   L A    
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472

Query: 379 ----------LSGGPPLGSGPPPPSIFSADLSDSSSSRL 407
                         PPL + P PP+ F      S S+ L
Sbjct: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 511



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 103/379 (27%), Positives = 130/379 (34%), Gaps = 46/379 (12%)

Query: 41  SASDPPLAPALPSGTAP----FLFSPGVLLPEPEYCP---PWRSPKKESPKISQRWRESK 93
           SA   P APA PS   P     L  P V  P  +  P   P  S    +P  S     S 
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308

Query: 94  PRG--NLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPC 151
           P     L      PP     S   P  + +    P P L   +    P P+  P+   P 
Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL---SPLATPPPQAPPALALPP 365

Query: 152 PPGVPSP--SPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPR 209
               PSP  SPP   L   + +        L Q       P S   S  ++     +PP 
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA------PFSPPPSPPVQAPF--SPPA 417

Query: 210 ERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPT 269
             P      SP+  P P   P +LAA   Q    P A+   PP+     +P   P P   
Sbjct: 418 SPPV-----SPSATP-PSQAPPSLAAPPLQVPPSPPAS---PPM-----SPSATPPPQ-A 462

Query: 270 PAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPL 329
           P P AAP L  +  P  A   L      A    Q LP+       +    P   LP  PL
Sbjct: 463 PPPLAAPPLQLAKPPPQAPPAL------ATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516

Query: 330 DF--PGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGS 387
               P +  VL+        S   S +L +P    +P P           AL+ GPP   
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576

Query: 388 GPPPPSIFSA-DLSDSSSS 405
              P S  S  DL+  SSS
Sbjct: 577 SRSPSSTLSGPDLAGHSSS 595



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 88/350 (25%), Positives = 119/350 (34%), Gaps = 60/350 (17%)

Query: 43  SDPPLAP-ALPSGTAP------FLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           + PPL+P A PS  AP       L +P    P P    P+  P       S       P 
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433

Query: 96  GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGV 155
                   +PP P       P A      PP P         +P P+  P+  TP    +
Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPLQAL 492

Query: 156 PSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPR 215
           PSP   P     Q                     P S + S+ +  +    PP + P   
Sbjct: 493 PSP---PASFPGQA--------------------PFSPSASLPMSPL--ATPPPQAPPVL 527

Query: 216 REDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAA 275
                   P P   P  L A RR  +  P  +   P L  A   PG  P P P+ +P++ 
Sbjct: 528 AAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLAL-APG--PPPPPSRSPSST 583

Query: 276 PALTPSSGPGSAALTLEEELQ------EAIRRAQLLP------------NRGIDDILEDQ 317
            +    +G  S+A +  EEL+      E    A   P            +RG    L  +
Sbjct: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 643

Query: 318 VEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSP-TNSSSPSP 366
             P  PLP  P   PGS D L    ++EG      S+ P+P      PSP
Sbjct: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGP----ESATPAPGALDPGPSP 689



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 70/277 (25%), Positives = 90/277 (32%), Gaps = 54/277 (19%)

Query: 38  PWISASDPPLAPAL--PSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           P+   + PP++P+   PS   P L +P + +P      P  SP    P            
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP----------- 460

Query: 96  GNLTYHQYMPP---EPRQGSRADPQAEGSALGPP------GPSLWEGTDSQQPHPRMKPS 146
                 Q  PP    P Q ++  PQA  +   PP       P+ + G     P   +  S
Sbjct: 461 ------QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514

Query: 147 PLTPCPPGVPS---------PSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSM 197
           PL   PP  P          P  PP    LQ  +         R         VSG + +
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR---------RPPTPGPDTSVSGPR-L 564

Query: 198 LLERMRGGAPPRERPKPRREDSP--AGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPR 255
            L    G  PP  R        P  AG                 G    +AAS  P    
Sbjct: 565 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624

Query: 256 AADTP-----GTAPAPTPTPAPAAAPALTPSSGPGSA 287
           AA  P     G AP      AP A     P++GPGSA
Sbjct: 625 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 661



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 77/317 (24%), Positives = 105/317 (33%), Gaps = 69/317 (21%)

Query: 133 GTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTL----KLEELTVSELRQQLRLRG 188
           G  ++ P  R  P  LTP PPG P P PP     L+ L     +    ++E    +    
Sbjct: 11  GAAARTPAARA-PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 189 LPVSGTKSMLLERMRGGAPPR-ERPKPRREDSPA-------------------------- 221
           +P S  ++      R  A  R ER  P +  SP                           
Sbjct: 70  IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129

Query: 222 ------GAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAA 275
                 G      K  AL+A  R+ +  P+  +  P + R +   GT     P PAP+A 
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSAR 188

Query: 276 PALTPSSGPGSAALTLEE----ELQEAIRRAQLL---------------------PNRGI 310
           P   P+ GP  +  +  E    E   A RR                         P R  
Sbjct: 189 PR-PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247

Query: 311 DDILEDQVEPDDPLPPIP--LDFPGSFDVLSPSPD-SEGLSSVFSSSLPSPTNSSSPSPR 367
                    P  P  P P  L       V  P  D +  L  + SS L +P+ S+ PSP 
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307

Query: 368 DPTDSLDWLEALSGGPP 384
            P  SL  L +    PP
Sbjct: 308 AP-PSLQTLPSPPATPP 323


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 60/276 (21%), Positives = 88/276 (31%), Gaps = 32/276 (11%)

Query: 145  PSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRG 204
            P   TP PP   + +PPP      T      T + +        LP + T S        
Sbjct: 1518 PPTTTPSPPTTTTTTPPP------TTTPSPPTTTPITPPTSTTTLPPTTTPS-------- 1563

Query: 205  GAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPS---AASHRPPLPRAADTPG 261
              PP     P    +P+        P  +       +  PS     +  PP       P 
Sbjct: 1564 -PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPT 1622

Query: 262  TAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPD 321
            T P   PT      P  TPS  P +                   P             P 
Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682

Query: 322  DPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSP------------SPRDP 369
             P+   P   P +  + +PSP +   S + +++ PS T + SP            +P  P
Sbjct: 1683 SPITTTP--SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPP 1740

Query: 370  TDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSSSS 405
            T ++  L   +   PL + P PPSI     S  S++
Sbjct: 1741 TTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTT 1776



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 57/255 (22%), Positives = 80/255 (31%), Gaps = 31/255 (12%)

Query: 145  PSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRG 204
            P   TP PP   + +PPP      T     +T +           P+S T +        
Sbjct: 1417 PPTTTPSPPTTTTTTPPP-----TTTPSPPITTTTTPPPTTTPSPPISTTTT-------- 1463

Query: 205  GAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADT---PG 261
              PP   P P    +    P     P          +  PS  +  P  P A+ T   P 
Sbjct: 1464 -PPPTTTPSP--PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPT 1520

Query: 262  TAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPD 321
            T P+P  T      P  TPS  P +  +T               P             P 
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSP-PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1579

Query: 322  DPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSP---SPRDPTDSLDWLEA 378
             P    P   P +    +P P +       +++ P PT + SP   +P  P  S   L  
Sbjct: 1580 PPTTTTP--SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL-- 1635

Query: 379  LSGGPPLGSGPPPPS 393
                PP  +  PPP+
Sbjct: 1636 ----PPTTTPSPPPT 1646



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 30/145 (20%), Positives = 49/145 (33%), Gaps = 34/145 (23%)

Query: 252  PLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGID 311
            P+ +   TP + P  TP+P P +   L P++ P     T                     
Sbjct: 1391 PMDKCITTP-SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP----------------- 1432

Query: 312  DILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSP---SPRD 368
                         PP     P      +P P +     + +++ P PT + SP   +P  
Sbjct: 1433 -------------PPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSP 1479

Query: 369  PTDSLDWLEALSGGPPLGSGPPPPS 393
            PT +       +  PP  + P PP+
Sbjct: 1480 PTTTPSPPTTTTTTPPPTTTPSPPT 1504



 Score = 33.1 bits (74), Expect = 0.48
 Identities = 40/190 (21%), Positives = 59/190 (31%), Gaps = 19/190 (10%)

Query: 206  APPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPA 265
            +PP   P P    +    P     P          +  PS        P    TP    +
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459

Query: 266  PTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLP 325
             T TP P   P+  P++ P     T               P             P  P  
Sbjct: 1460 TTTTPPPTTTPS-PPTTTPSPPTTTPS-------------PPTTTTTTPPPTTTPSPP-T 1504

Query: 326  PIPLDFPGSFDVL----SPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSG 381
              P+  P S   L    +PSP +   ++   ++ PSP  ++  +P   T +L      S 
Sbjct: 1505 TTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564

Query: 382  GPPLGSGPPP 391
             P   + PPP
Sbjct: 1565 PPTTTTTPPP 1574



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 53/245 (21%), Positives = 76/245 (31%), Gaps = 28/245 (11%)

Query: 36   PDPWISASDPPLA-PALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKP 94
            P P  + + PP   P+ P+ T P    P +    P   PP  +P   SP  +     + P
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPS--PPTITTTTP---PPTTTP---SPPTTTT---TTP 1612

Query: 95   RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSP---LTPC 151
                T      P P   +   P    + L P        T +  P P   PSP    TP 
Sbjct: 1613 PPTTT------PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666

Query: 152  PPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRER 211
            PP   + +PPP      T      T             P +   S +       +     
Sbjct: 1667 PPITTTTTPPP----TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPS 1722

Query: 212  PKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPA 271
            P P    +P+    P      +       +  P   +   PLP +   P  +P  T TP 
Sbjct: 1723 PPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTT---PLPPSITPPTFSPFSTTTPT 1779

Query: 272  PAAAP 276
                P
Sbjct: 1780 TPCVP 1784



 Score = 32.3 bits (72), Expect = 0.81
 Identities = 39/163 (23%), Positives = 60/163 (36%), Gaps = 19/163 (11%)

Query: 133  GTDSQQPHPRMKPSPLTPCP-PGVPSPSPPPHKLELQTLKLEELTVSE------LRQQLR 185
            GT +    P    + +TP P P      PP H     T  + ELT S         Q  R
Sbjct: 4169 GTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHT---STAPIAELTTSNPPPESSTPQTSR 4225

Query: 186  LRGLPVSGTKSMLLE-----RMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQG 240
                P++ + ++L        M   APP     P           P     +      +G
Sbjct: 4226 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRG 4285

Query: 241  SVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSG 283
            +   S+++   P P    T  T+ A TPTP P + P++  ++G
Sbjct: 4286 TTTGSSSA---PTPSTVQTTTTS-AWTPTPTPLSTPSIIRTTG 4324


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 77/297 (25%), Positives = 108/297 (36%), Gaps = 44/297 (14%)

Query: 73  PPWRSPKKESP--KISQRWRESKPRGNLTYHQYMPPEPRQGSRAD---PQAEGSALGPPG 127
           PP R+ ++E P    ++   E  P    +Y  Y+PPEP + +  D   P +E     PP 
Sbjct: 383 PPRRATREEPPGAPFAENTAERFPP---SYTSYLPPEPSRPTDQDYRPPASEAPPPEPPE 439

Query: 128 PSLWEGTDSQQP---HPRMKPSPLTPCPPGVPSPSPPPHKLEL-QTLKLEELTVSELRQQ 183
           P    G     P     R  P P +P   G P+P      +   Q   L+      L++Q
Sbjct: 440 PGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQ 499

Query: 184 LRLRGLPVSGTK------SMLLERM-----------RGGAPPRERPKPRREDSPAGAPWP 226
                   S T+      SM+L               G   P   P    + +P G+  P
Sbjct: 500 RSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEP 559

Query: 227 ---RLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTP--APAAAPALTPS 281
              R  PKA       G  + S  S    +  + D  G +P P PTP   P   P   P 
Sbjct: 560 GATRESPKA------NGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPP 613

Query: 282 SGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVL 338
             P  A+L L     +    A LLP R  D     +  P  P PP   DF  S +++
Sbjct: 614 PPPYLASLPLGYPPHQP---AYLLPPRP-DGPPPPEYPPPPPPPPHIYDFVNSLELM 666



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 43/157 (27%), Positives = 60/157 (38%), Gaps = 19/157 (12%)

Query: 152  PPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRER 211
            P  +PS SPPP ++ + T    E+ V E     R+ G PV+          R   P  E 
Sbjct: 1071 PAALPSASPPPREVPVPTPAPVEVPVPE-----RVAGSPVTPLPEQEASPARPAGPTEES 1125

Query: 212  PKP---RREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTP 268
            P     R  + PAG P P  +P            +PS+     P P+      +  A   
Sbjct: 1126 PPSAPLRPPEPPAGPPAPAPRP----------DERPSSPIPLLPPPKKRRKTVSFSAIEV 1175

Query: 269  TPAPAAAPALTPSSG-PGSAALTLEEELQEAIRRAQL 304
             PAP   PA  P +  PG A+      ++  IR   L
Sbjct: 1176 VPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPL 1212



 Score = 36.2 bits (82), Expect = 0.056
 Identities = 70/291 (24%), Positives = 101/291 (34%), Gaps = 57/291 (19%)

Query: 45  PPLAPALPSGTAPF-LFSPGVLLPEPEYCPPWRSPKKESP-------KISQRWRESKPRG 96
           PP APA     AP     PG     P+         + SP       +IS   R   P  
Sbjct: 541 PPPAPANFEDVAPTGSGEPGATRESPKA----NGQNQASPCSSGDDMEISDDDRGGSPPP 596

Query: 97  NLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVP 156
             T  Q  PP P       P      LG P           QP   + P P  P PP  P
Sbjct: 597 APTPPQQPPPPPPPPPPPPPYLASLPLGYP---------PHQPAYLLPPRPDGPPPPEYP 647

Query: 157 SPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVS-GTKSMLLERMR-----------G 204
            P PPP  +      LE +     R   +  G+P+S   ++ +L R+             
Sbjct: 648 PPPPPPPHIYDFVNSLELMD----RLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLIAAS 703

Query: 205 GAPPRER------PKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAAD 258
             PP         P P  +++  G P+      AL A  ++G    S  ++  P+P AA+
Sbjct: 704 AGPPGGAFGEAFLPFPPPQEAAYGLPY------ALYAQGQEGRGAYSREAYHLPMPMAAE 757

Query: 259 -------TPGTAPAPTPTPAPAAAPALTPSSGP-GSAALTLEEELQEAIRR 301
                  +   A  P    A  A     P++G  G     L +E++  ++R
Sbjct: 758 PLPSSSVSGEEARLPPREEAELAEGKTLPTAGTVGRVLAMLVQEMKSIMQR 808



 Score = 35.8 bits (81), Expect = 0.073
 Identities = 26/87 (29%), Positives = 31/87 (35%)

Query: 200  ERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADT 259
            E  R  A P   P PR    P  AP     P+ +A +      +  A+  RP  P     
Sbjct: 1067 EEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESP 1126

Query: 260  PGTAPAPTPTPAPAAAPALTPSSGPGS 286
            P     P   PA   APA  P   P S
Sbjct: 1127 PSAPLRPPEPPAGPPAPAPRPDERPSS 1153



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 34/144 (23%), Positives = 47/144 (32%), Gaps = 8/144 (5%)

Query: 234  AAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAP--ALTPSSGPGSAALTL 291
            +++    S   S++       R A  P  +P P   P P  AP     P    GS    L
Sbjct: 1049 SSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPL 1108

Query: 292  EEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPL--DFPGSFDVLSPSPDSEGLSS 349
             E+     R A           L     P  P  P P   + P S   L P P     + 
Sbjct: 1109 PEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTV 1168

Query: 350  VFSS----SLPSPTNSSSPSPRDP 369
             FS+      P P  ++ P  + P
Sbjct: 1169 SFSAIEVVPAPEPPPATPPQAKFP 1192


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 99/386 (25%), Positives = 129/386 (33%), Gaps = 84/386 (21%)

Query: 44   DPPLAPALPSGT--APFLFSPGVLLPEPEYCPPWRS---------PKKESPKISQRWRES 92
            DPPL P   S    AP  FS G  +  P Y P  R          P   SP         
Sbjct: 1842 DPPLRPDSGSAPPPAPRSFS-GARIKVPNYSPSRRPLGGVSFGPLPSPGSPS-------- 1892

Query: 93   KPRGNLTYH------QYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQ------PH 140
                +LT+H         P  PR+  R  P A       P PS W     +       P 
Sbjct: 1893 ----SLTHHIPTVGDPDFPAPPRRSRRPSPLAPR-----PPPSRWASPPLKTSPQLRVPP 1943

Query: 141  PRMKPSPLTP-----CPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTK 195
            P    + LTP      PPG P+PSPPP + +L     +   VS L          + GT+
Sbjct: 1944 PTSVVTALTPTSGELAPPG-PAPSPPPPE-DLGPDFEDMEVVSGLSAADLDFAASLLGTE 2001

Query: 196  SMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPR 255
                E +  GA       P        +P  R     +      G + PSA    P  PR
Sbjct: 2002 PFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPG-LAPSAT---PGAPR 2057

Query: 256  AADTPGTAPAPTPTPAPAAAPAL--TPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDI 313
                 G              P    TP SGPG     +     +  R  + LP+  +D +
Sbjct: 2058 IEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFV 2117

Query: 314  LEDQVEPDD--------PLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPS 365
            L++   P D         LPP P        + + S  S+GL++               S
Sbjct: 2118 LKNLGGPGDGGAGPREESLPPAP-------PLANGSQPSQGLTA---------------S 2155

Query: 366  PRDPTDSLDWLEALSGGPPLGSGPPP 391
            P DPT +  WL    G   L  GP P
Sbjct: 2156 PADPTRTFAWLPGAPGVRVLSLGPAP 2181



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 80/345 (23%), Positives = 115/345 (33%), Gaps = 71/345 (20%)

Query: 79  KKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQ 138
           KKE  +  +   E + R      + MP   ++ ++  P         P P L   + S  
Sbjct: 368 KKEEEEKDKEGEEKEERA--VAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPP 425

Query: 139 PHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSML 198
           P P   P P    PP +PSP PPP                E +++     +P +      
Sbjct: 426 P-PLCPPPPPPVSPPPLPSPPPPP--------------AQEEQEESPPPVVPAT------ 464

Query: 199 LERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAAD 258
             R RG  P     +  RE + AG                     P   S  PP P    
Sbjct: 465 CSRKRGRPPLTPSQRAEREAARAG---------------------PEGTS--PPTP---- 497

Query: 259 TPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQV 318
           TP TA    P  +P  AP  T          T  + +++ I       +  +       +
Sbjct: 498 TPSTATGGPPEDSPTVAPKST----------TFLKNIRQFIMPVVSARSSRVIKTPRRFM 547

Query: 319 EPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSP---------RDP 369
           + D P PP     P     ++ SP      +   S   +PT  S+P P         R+P
Sbjct: 548 DEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP 607

Query: 370 TDSLDWLEALSGGPPLGSGPPPPSIFSADLSDSSSSRLWDLLEDP 414
           T    W       PP    PPPP   S   + ++SSR   LL  P
Sbjct: 608 T--FRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAP 650



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 98/389 (25%), Positives = 128/389 (32%), Gaps = 67/389 (17%)

Query: 45  PPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKIS------QRWRESKP---- 94
           PPL P  PS   P    P    P P  CPP   P    P  S      Q  +E  P    
Sbjct: 404 PPLTPPAPSPPPPL--PPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVV 461

Query: 95  RGNLTYHQYMPP-EPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPP 153
               +  +  PP  P Q +    + E +  GP G S           P   PS  T  PP
Sbjct: 462 PATCSRKRGRPPLTPSQRA----EREAARAGPEGTS----------PPTPTPSTATGGPP 507

Query: 154 GVPSPSPPPHKLELQTLKLEELTVSELRQQLRLR----------GLPVSGTKSMLLERMR 203
                  P     L+ ++   + V   R    ++            P     S +L    
Sbjct: 508 EDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPI 567

Query: 204 GGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKP-----SAASHRPPLPRAAD 258
             +PP  + +P    SP  AP P   P  L   RR    +P     S     PP P A  
Sbjct: 568 TTSPPVPQ-EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP 626

Query: 259 TPGTAPAPTPTPAPAAA---PAL--TPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDI 313
            P   PAP+P PAPA +   P L   P   P  A L + E +          P  G  + 
Sbjct: 627 PP---PAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTP-------PPLGAPEA 676

Query: 314 LEDQVEP--DDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTD 371
            E +  P  D P  P P     +  +  P       + V +   P    + S  P+    
Sbjct: 677 PEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQ 736

Query: 372 SLDWLEALSG-------GPPLGSGPPPPS 393
            L  L+AL          PP     PPPS
Sbjct: 737 LLQPLQALQTQLLPQALPPPQPQLQPPPS 765



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 79/325 (24%), Positives = 116/325 (35%), Gaps = 53/325 (16%)

Query: 18  RSVLQLRIHRRNQEQISDPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCP-PWR 76
           RS   ++  RR  ++     P +  S P L P  P  T+P +      +P P   P P  
Sbjct: 535 RSSRVIKTPRRFMDEDPPKPPKVEVS-PVLRP--PITTSPPVPQEPAPVPSPPRAPTPPS 591

Query: 77  SPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDS 136
           +P     K     RE   R      +  PP P       P    +   PP P+    T S
Sbjct: 592 TPVPLPEKRRSILREPTFRWTSLTRELPPPPPA------PPPPPAPSPPPAPA----TSS 641

Query: 137 QQP-------------HPRMKPSPLTPCPPGVP-SPSPPPHKLELQTLKLEELTVSELRQ 182
           ++P             H ++  S LTP P G P +P P P   +    + E   V     
Sbjct: 642 RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNH 701

Query: 183 QLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSV 242
               R  PV  T                    + E SP GAP     P+  A       +
Sbjct: 702 LSLPRFAPVVTTPV------------------KAEVSPHGAPALSNGPQTQAQL-----L 738

Query: 243 KPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALT-LEEELQEAIRR 301
           +P  A     LP+A   P     P P+P           +G GS  L+ +EE++   ++R
Sbjct: 739 QPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKR 798

Query: 302 AQLLPNRGIDDILEDQVEPDDPLPP 326
           A++   + ID   + +V    PL P
Sbjct: 799 AKVQLFK-IDQQQQQKVAASMPLSP 822



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 43/165 (26%), Positives = 54/165 (32%), Gaps = 42/165 (25%)

Query: 45   PPLAPAL-PSGTAPFLFSPGVLL----------PEPEYCPPWRSPKKESPKISQRWRESK 93
            PPL P + P+    +   PG LL          P P   PP  +    S   S   +  +
Sbjct: 2218 PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIR 2277

Query: 94   PRGNLTYHQYMPPEPR--QGSRADPQAEGSALGPPGPSLWEGTDS--------------- 136
             +   T+    PP P   +  R D   E S   P  P L  G  S               
Sbjct: 2278 VKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDL 2337

Query: 137  ---------QQPHPRMKPSPLTPC----PPGVPSPSPPPHKLELQ 168
                     + P P  + SPL P     PP VP   PP   LE Q
Sbjct: 2338 DRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPD-GPPDLLLESQ 2381


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 56/219 (25%), Positives = 84/219 (38%), Gaps = 16/219 (7%)

Query: 77  SPKKESPKISQRWRESKPRGNLTYHQYMPPEPR-QGSRADPQAEGSALGPPGPSLWEGTD 135
           SP++ S  + +  + S  R      +   P P  +     P+    ++    PS+ E T 
Sbjct: 181 SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATS 240

Query: 136 SQQPHPRMKPSPLTPCPPGVPSPSPPPH-KLELQTLKLEELTVSELRQQLRLRGLPVSGT 194
           +       KP P+    P    PSP  + K E +  K    + S  + + R R    S T
Sbjct: 241 TSDILKVPKPEPI----PEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHT 296

Query: 195 KSMLLERMRGGA-PPRERPKPRREDSPAGAPWPRLKP--------KALAAARRQGSVKPS 245
           +     R R  +  PR RP PRR  SP     PR  P        ++    RR+ S   S
Sbjct: 297 RPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLS 356

Query: 246 AASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGP 284
            +S      R+   P   P  T +P P     L+PS+ P
Sbjct: 357 GSSSSSSSSRSRSPPKKPPKRTSSP-PRKTRRLSPSASP 394



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 93/397 (23%), Positives = 137/397 (34%), Gaps = 93/397 (23%)

Query: 6   SSQRSQIIRSKFRSVLQLRIHRRNQEQISDPDPWISASDPPLAPALPSGTAPFLFSPGVL 65
           S  RS   R+K RS       +    ++  P+P +   +P +  A  + T+  L  P   
Sbjct: 196 SHSRSPRHRTKSRSPSPAPEKKEKTPEL--PEPSVKVKEPSVQEA--TSTSDILKVPKPE 251

Query: 66  -LPEPEYCPPWRSPKKESPKISQRWRE---SKPRGNLTYHQYMPPEPRQGSRADPQAEGS 121
            +PEP+   P ++ KKE  K   R R    SK R            PR+  R+  ++   
Sbjct: 252 PIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSY-- 309

Query: 122 ALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELR 181
                       +  ++P PR +PSP    PP    P PP H+     ++         R
Sbjct: 310 ------------SPRRRPSPRRRPSPRRRTPPR-RMPPPPRHRRSRSPVRRRR------R 350

Query: 182 QQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGS 241
               L G   S + S      R  +PP++ PK  R  SP      RL P A    RR   
Sbjct: 351 SSASLSGSSSSSSSS------RSRSPPKKPPK--RTSSPPRKT-RRLSPSASPPRRRH-- 399

Query: 242 VKPSAASHRPPLPRAADTP--------------------------GTAPAPTPTPAPAAA 275
            +PS  +  PP  R + TP                          GT    +P+PAP   
Sbjct: 400 -RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR 458

Query: 276 PALTPSS-----GPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLD 330
                 S     G  +AA ++++  Q   +  Q   + G     ED+             
Sbjct: 459 KVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE------------- 505

Query: 331 FPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPR 367
                    P         V      SP+ S+SPSPR
Sbjct: 506 --------RPKRSHVKNGEVGRRRRHSPSRSASPSPR 534



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 75/303 (24%), Positives = 111/303 (36%), Gaps = 65/303 (21%)

Query: 69  PEYCPPWRSPKKESPKISQRWRESKP-RGNLTYHQYMPPEPRQGSRADPQAEGSALGPPG 127
           P   PP R  +  +P   +R     P R + +  +Y PP  R+ S             P 
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS-------------PS 607

Query: 128 PSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLR 187
           P     T S  P P+ + SP +P P    S SPPP                      + R
Sbjct: 608 PPPKRRTASPPPPPKRRASP-SPPPKRRVSHSPPP----------------------KQR 644

Query: 188 GLPVSGTKS-MLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSA 246
             PV+  +S  L  + R G+ P    +  R   P     P  +P+A           P  
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA-----------PQT 693

Query: 247 ASHRPPLPR-AADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLL 305
           +S  PP+ R A+ +P    +P+P+  P    + TP       A +      +++RR    
Sbjct: 694 SSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAAS---PSPQSVRRVS-- 748

Query: 306 PNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPS 365
            +R +    E   +   P PP P        V S SP +    +V      SPT S SP 
Sbjct: 749 SSRSVSGSPEPAAK-KPPAPPSP--------VQSQSPSTNWSPAVPVKKAKSPTPSPSP- 798

Query: 366 PRD 368
           PR+
Sbjct: 799 PRN 801



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 75/318 (23%), Positives = 113/318 (35%), Gaps = 66/318 (20%)

Query: 79  KKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQ 138
           +  SP   +R +E+ PRG        PP  R+ S             P P+         
Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS-------------PSPA--------- 564

Query: 139 PHPRMKPSPLTPCPPGVPSPSPPPHKLELQTLKLE---ELTVSELRQQLRLRGLPVSGTK 195
           P PR + +P TP PP   +PSPPP +      +     +   S      R    P    K
Sbjct: 565 PPPRRRRTP-TP-PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622

Query: 196 SMLLERMRGGAPPRER----PKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRP 251
                R     PP+ R    P P++  SP      R  P   +  R+  S   S    R 
Sbjct: 623 ----RRASPSPPPKRRVSHSPPPKQRSSPV---TKRRSPSLSSKHRKGSSPSRSTREARS 675

Query: 252 PLPRAADTPGTAP-APTPTPAP-------AAAPALTPSSGPGSAALTLEEELQE--AIRR 301
           P P    +P   P AP  + +P       +++P    S  P +  +       E   I++
Sbjct: 676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKK 735

Query: 302 AQLLPNRGIDDI-----LEDQVEPDDPLPPIPLDFPGSFDVLSPSP-DSEGLSSVFSSSL 355
           A     + +  +     +    EP    PP P           PSP  S+  S+ +S ++
Sbjct: 736 AASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP-----------PSPVQSQSPSTNWSPAV 784

Query: 356 P-SPTNSSSPSPRDPTDS 372
           P     S +PSP  P +S
Sbjct: 785 PVKKAKSPTPSPSPPRNS 802



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 90/362 (24%), Positives = 118/362 (32%), Gaps = 92/362 (25%)

Query: 76  RSPKKESPKISQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTD 135
           RSP K+ PK +     S PR          P PR+  R  P A      PP  +    T 
Sbjct: 368 RSPPKKPPKRTS----SPPRKTRRLSPSASP-PRRRHRPSPPAT-----PPPKTRHSPTP 417

Query: 136 SQQPHPRMKPSPLTPCPPG-------------VPSPSPPPHKLELQTLKLEE---LTVSE 179
            Q    R     ++P                  PSP+P P K+EL   + ++   +  ++
Sbjct: 418 QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAAD 477

Query: 180 LRQQLRL--RGLPVSGTKSMLLERMRGGAPPRERPKP-----RREDSPA--GAPWPRLKP 230
             QQ R   R    S + S          P R   K      RR  SP+   +P PR   
Sbjct: 478 SVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR--- 534

Query: 231 KALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALT 290
                 +RQ    P     R P P     P T    +P+PAP      TP+  P      
Sbjct: 535 ------KRQKETSPRGRRRRSPSP-----PPTRRRRSPSPAPPPRRRRTPTPPPR----- 578

Query: 291 LEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSV 350
                    RR    P R           P    PPI   +       SPSP  +  +  
Sbjct: 579 ---------RRTPSPPPR------RRSPSPRRYSPPIQRRY-------SPSPPPKRRT-- 614

Query: 351 FSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPLGSGPPP------PSIFSADLSDSSS 404
            +S  P P   +SPSP            +S  PP      P      PS+ S     SS 
Sbjct: 615 -ASPPPPPKRRASPSPPPK-------RRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP 666

Query: 405 SR 406
           SR
Sbjct: 667 SR 668



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 64/299 (21%), Positives = 100/299 (33%), Gaps = 37/299 (12%)

Query: 27  RRNQEQISDPDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKK-ESPKI 85
           +R       P   +S S PP   + P        SP +     +   P RS ++  SP+ 
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSSPVTKRR---SPSLSSKHRKGSSPSRSTREARSPQP 678

Query: 86  SQRWRESKPRGNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWE-GTDSQQPHPRMK 144
           ++R   S PR         PP  R+G+ + PQ   S    P PS       S+ P P+  
Sbjct: 679 NKRHSPS-PRPRAPQTSSSPPPVRRGASSSPQRRQS----PSPSTRPIRRVSRTPEPKKI 733

Query: 145 PSPLTPCP-----------------PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLR 187
               +P P                 P    P  PP  ++ Q+          +++     
Sbjct: 734 KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPT 793

Query: 188 GLPVSGTKSMLLERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAA 247
             P     S   +   G    +++ K  ++D          K KA+AAA        +AA
Sbjct: 794 PSPSPPRNSD--QEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAA--------AAA 843

Query: 248 SHRPPLPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLP 306
           +  P    AA T      P   P P                  L E+   ++R+AQ+ P
Sbjct: 844 AVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSP 902


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 106/384 (27%), Positives = 134/384 (34%), Gaps = 74/384 (19%)

Query: 52  PSGTAPFLFSPGVLLPEPEYCPPWRSPKK--ESPKISQRWRE--SKPRGNLTYH------ 101
           P  T   L SP      P   PP ++P     SP +        S     LT H      
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493

Query: 102 ---QYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSP 158
               + P  P       P    S+L PP         S Q  P    S  TP    +PS 
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPP---------SLQTPPA---SLTTPPLENLPSL 541

Query: 159 SPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRRED 218
           +PPP    LQT     LT   L         P+    S L        PP E P      
Sbjct: 542 APPP----LQTASAP-LTTPHLETPPCPAPCPLQAPPSPLT------TPPPETP------ 584

Query: 219 SPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAAAPAL 278
           S    P P+  P ALA+   QG   P  +    P P+A       P   P P+P A+P L
Sbjct: 585 SSIATPPPQAPP-ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP-PSPPASPPL 642

Query: 279 TPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDF-PGSFDV 337
           +P + P   A                 PN     +L+    P  P PP+   F P +   
Sbjct: 643 SPLATPSPQA-----------------PNALAVHLLQAPFSP-PPSPPVQAPFSPPASPP 684

Query: 338 LSPS--PDSEGLSSVFSSSL---PSPTNS--SSPSPRDPTDSLDWLEALSGGPPLGSGPP 390
           +SPS  P S+   S+ +  L   PSP  S   SPS   P  +   L A    PPL   P 
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA----PPLQVPPS 740

Query: 391 PPSIFSADLSDSSSSRLWDLLEDP 414
           PP+      S +   R+  LL  P
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAP 764



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 92/351 (26%), Positives = 128/351 (36%), Gaps = 51/351 (14%)

Query: 38  PWISASDPPLAPAL--PSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           P+   + PP++P+   PS   P L +P + +P      P  SP    P  +     + P 
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735

Query: 96  GNLTYHQYMPPEPRQGSRADPQAEGSALGPPG-PSLWEGTDSQQPHPRMKPSPLTPCPPG 154
                   +PP P     A P    SA  PP  P L      Q P     P+ L   P  
Sbjct: 736 -------QVPPSPP----ASPPMSPSATPPPRVPPLLAAPPLQVPPS--PPASLPMSPLA 782

Query: 155 VPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKP 214
            P P  PP    L T  L+ L         +    P S + S+ +  +    PP + P  
Sbjct: 783 KPPPQAPP---ALATPPLQALPSPPASFPGQA---PFSPSASLPMSPL--ATPPPQAPPV 834

Query: 215 RREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAPTPTPAPAA 274
                    P P   P  L A RR  +  P  +   P L  A   PG  P P P+ +P++
Sbjct: 835 LAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLAL-APG--PPPPPSRSPSS 890

Query: 275 APALTPSSGPGSAALTLEEELQ------EAIRRAQLLP------------NRGIDDILED 316
             +    +G  S+A +  EEL+      E    A   P            +RG    L  
Sbjct: 891 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950

Query: 317 QVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSP-TNSSSPSP 366
           +  P  PLP  P   PGS D L    ++EG      S+ P+P      PSP
Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGP----ESATPAPGALDPGPSP 997



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 97/402 (24%), Positives = 128/402 (31%), Gaps = 70/402 (17%)

Query: 41  SASDPPLAPALPSGTAPF---LFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGN 97
           SA   P APA PS   P       P  + P  +   P   P   SP  +     +K R  
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317

Query: 98  LTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPS 157
                   P P     + P A    L PP PS      +    P   PS   P     P 
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377

Query: 158 PSPP----------PHKLELQTLKL--EELTVSELRQQLRLRGLPVSGTKSMLLERMR-- 203
            +PP          PH L   +L+     L +S L+    L    +  T S L    R  
Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437

Query: 204 ----------GGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKP-----SAAS 248
                        PP   P       PA  P       A++      ++ P     S AS
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497

Query: 249 HRPPLP--------------RAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEE 294
           H P  P               A  +  T PA   TP     P+L P     ++A      
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557

Query: 295 LQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDS-EGLSSVFSS 353
           L+     A                 P  PL   P + P S  + +P P +   L+S    
Sbjct: 558 LETPPCPAPC-----------PLQAPPSPLTTPPPETPSS--IATPPPQAPPALASPPLQ 604

Query: 354 SLPSPTNS--SSPSPRDPTDSLDWLEALSGGPPLGSGPPPPS 393
            LPSP  S  ++P P+ P        AL   PPL + P PP+
Sbjct: 605 GLPSPPLSPLATPPPQAPPXL-----AL---PPLQAPPSPPA 638



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 102/389 (26%), Positives = 131/389 (33%), Gaps = 49/389 (12%)

Query: 41  SASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTY 100
           S + PPL  A    T P L +P    P P   PP  SP    P          P    T 
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP--SPLTTPPP-------ETPSSIAT- 589

Query: 101 HQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLT--PCPPGVP-- 156
               PP     + A P  +G    P  P     T   Q  P +   PL   P PP  P  
Sbjct: 590 ----PPPQAPPALASPPLQGLPSPPLSPL---ATPPPQAPPXLALPPLQAPPSPPASPPL 642

Query: 157 ----SPSPP-PHKLELQTLKLEELTVSELRQQLRLR---GLPVSGTKSMLLERMRGGAPP 208
               +PSP  P+ L +  L+           Q         PVS + +   +     A P
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702

Query: 209 RERPKPRREDSPAGAPW---PRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPA 265
             +  P    SP  +P    P   P  LAA   Q    P A+   PP+     +P   P 
Sbjct: 703 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS---PPM-----SPSATPP 754

Query: 266 PTPTPAPAAAPALTPSSGPGSAALT------LEEELQEAIRRAQLLPNRGIDDILEDQVE 319
           P   P  AA P   P S P S  ++       +     A    Q LP+       +    
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814

Query: 320 PDDPLPPIPLDF--PGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLE 377
           P   LP  PL    P +  VL+        S   S +L +P    +P P           
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874

Query: 378 ALSGGPPLGSGPPPPSIFSA-DLSDSSSS 405
           AL+ GPP      P S  S  DL+  SSS
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSS 903



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 92/375 (24%), Positives = 135/375 (36%), Gaps = 62/375 (16%)

Query: 48  APALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPRGNLTYHQYMPPE 107
           A A  +   P   +PG+L P P       SP+   P      R     G +         
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62

Query: 108 PRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLEL 167
              G    P++   A    GP+   GT S+ P  R   S      P   + SP P     
Sbjct: 63  GGIGGATIPESAPRA----GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP----- 113

Query: 168 QTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPK-------PRREDS- 219
                   + +     L  +GL +S  +++     RG A   E PK        RR+ S 
Sbjct: 114 -VSSPGRASGTTRPGPLGQKGLRISAEETV----ARGKA--TEAPKRSALSAGARRDTSG 166

Query: 220 -PAGAPWPRLKPKALAAARRQGSVKPS-AASHRPPL--PR-----AADTPGTAPAPTPTP 270
              G P P +  ++ AA    G  +P+ +A  RPP   PR     A++   T P+P    
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226

Query: 271 APAAAPAL------------TPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQV 318
            P+A   L            TP S P  +  +     +     +Q  P +G+  +   QV
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQV 285

Query: 319 EP--DDPLPPI-PLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDW 375
            P   D  P + PL    S  + +PSP     S   +  +P P N+++P P     S   
Sbjct: 286 TPPRKDAAPALGPL---SSSPLATPSP-----SGTKARPVPPPDNAATPLPATLPPSPPL 337

Query: 376 LEALSGGPPLGSGPP 390
              L   PP  S PP
Sbjct: 338 ATPLPLAPPSPSAPP 352



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 70/262 (26%), Positives = 92/262 (35%), Gaps = 18/262 (6%)

Query: 111 GSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTPCPPGVPSPSPPPHKLELQTL 170
           G+R D    G   G P P++   + +      + P P     P  P+  P          
Sbjct: 159 GARRD--TSGPTPGTPSPAMARRSRAAGTEVGL-PRPAPSARPRPPTEGPRKSVSSASEH 215

Query: 171 KLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERPKPRRED-SPAGAPWPRLK 229
              E + +  R+     GL    ++S+        +P R  P  R    +PA    P  K
Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP--K 273

Query: 230 PKALAAARRQGSVKP--SAASHRPPL---PRAADTP-GTAPAPTPTPAPAAAP--ALTPS 281
           PK L A R      P   AA    PL   P A  +P GT   P P P  AA P  A  P 
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP 333

Query: 282 SGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPS 341
           S P +  L L      A    Q LP+         Q  P    P  P+  P S   + P 
Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPATP--PSQAPPSMTTP--PMQAPPSLQTIPPI 389

Query: 342 PDSEGLSSVFSSSLPSPTNSSS 363
                L+S    + PSP   SS
Sbjct: 390 QVPHSLTSPSLQAPPSPLALSS 411


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 57/199 (28%), Positives = 68/199 (34%), Gaps = 28/199 (14%)

Query: 95  RGNLTYHQYMPPEPRQGSRADPQAEGSALG-----PPGPSLWEGTDSQQPHPRMKPSPLT 149
           RG L  H +  P P  G   +    G   G     PP P        QQP P+ +P P  
Sbjct: 25  RGGL--HDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQ-QPPPQQ 81

Query: 150 PCPPGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPR 209
           P PP  P P P PH+ +      ++ +   + Q       P  G          G APP 
Sbjct: 82  P-PPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPG----PAPGV---------GSAPPA 127

Query: 210 ERPKPRREDSPAGAP---WPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPAP 266
               P      +GAP    P   P    A     S  P A    PP      TP  A  P
Sbjct: 128 SSSAPPATPPTSGAPPGSGPGPTPTPPPAVT---SAPPGAPPPTPPSSGVPTTPPQAGGP 184

Query: 267 TPTPAPAAAPALTPSSGPG 285
            P PA    P   P  GPG
Sbjct: 185 PPPPAAVPGPGPGPKQGPG 203



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 37/137 (27%), Positives = 45/137 (32%), Gaps = 20/137 (14%)

Query: 45  PPLAPALPSGTAPFLFSPGVLLPEPEYCPP-----WRSPKKESPKISQRWRESKPRGNLT 99
           PP    L     P    PG   P+P   PP      + P  + P   Q      P     
Sbjct: 34  PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQP 93

Query: 100 YHQYMPPEPRQGSRADPQAEG--------------SALGPPGPSLWEGTDSQQPHPRMKP 145
           + Q  PP P Q S     A+G              S+  P  P          P P   P
Sbjct: 94  HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP 153

Query: 146 SP-LTPCPPGVPSPSPP 161
            P +T  PPG P P+PP
Sbjct: 154 PPAVTSAPPGAPPPTPP 170



 Score = 37.0 bits (84), Expect = 0.033
 Identities = 42/191 (21%), Positives = 58/191 (30%), Gaps = 60/191 (31%)

Query: 204 GGAPPRERPKPRREDS--PAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPG 261
           G  PP   P P ++    P   P P+  P        Q    P      PP P+ +  P 
Sbjct: 55  GPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ----PHQQQQPPPPPQDSSKPV 110

Query: 262 TAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPNRGIDDILEDQVEPD 321
            A  P P P   +AP  + S+ P +                                   
Sbjct: 111 VAQGPGPAPGVGSAPPASSSAPPAT----------------------------------- 135

Query: 322 DPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSG 381
              PP     PGS    +P+P     S+   +  P+P +S  P+                
Sbjct: 136 ---PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTT--------------- 177

Query: 382 GPPLGSGPPPP 392
            PP   GPPPP
Sbjct: 178 -PPQAGGPPPP 187



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 24/85 (28%), Positives = 31/85 (36%), Gaps = 4/85 (4%)

Query: 317 QVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWL 376
           Q  P  P P  P   P       P P  +  S    +  P P      +P   + +    
Sbjct: 76  QPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPAT 135

Query: 377 EALSGGPPL-GSGP---PPPSIFSA 397
              SG PP  G GP   PPP++ SA
Sbjct: 136 PPTSGAPPGSGPGPTPTPPPAVTSA 160



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 35/130 (26%), Positives = 44/130 (33%), Gaps = 27/130 (20%)

Query: 36  PDPWISASDPPLAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPKISQRWRESKPR 95
           P P + ++ PP + + P  T P   +P    P P   PP        P ++     S P 
Sbjct: 117 PAPGVGSA-PPASSSAPPATPPTSGAPPGSGPGPTPTPP--------PAVT-----SAPP 162

Query: 96  GNLTYHQYMPPEPRQGSRADPQAEGSALGPPGPSLWEGTDSQQPHPRMKPSPLTP---CP 152
           G         P P   S   P     A GPP P          P P+  P P  P     
Sbjct: 163 G--------APPPTPPSSGVPTTPPQAGGPPPPP--AAVPGPGPGPKQGPGPGGPKGGKM 212

Query: 153 PGVPSPSPPP 162
           PG P P   P
Sbjct: 213 PGGPKPGGGP 222


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.131    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,628,926
Number of Sequences: 37866
Number of extensions: 2010988
Number of successful extensions: 29819
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 565
Number of HSP's successfully gapped in prelim test: 1664
Number of HSP's that attempted gapping in prelim test: 13217
Number of HSP's gapped (non-prelim): 10982
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.