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Search of human proteins with 194353966
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo
sapiens]
(4158 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 8309 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 2708 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 2631 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2597 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 2551 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2172 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 2159 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 2048 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 2027 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 1993 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1989 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1989 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1964 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1892 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1397 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1305 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 1276 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 400 e-110
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 298 6e-80
gi|223555933 dynein, axonemal, heavy polypeptide 14 isoform 2 [H... 65 1e-09
gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo sapiens] 63 7e-09
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 55 1e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 52 2e-05
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 51 3e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 51 3e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 50 5e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 50 5e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 50 5e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 50 5e-05
gi|71061468 centromere protein E [Homo sapiens] 49 8e-05
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 8309 bits (21559), Expect = 0.0
Identities = 4158/4158 (100%), Positives = 4158/4158 (100%)
Query: 1 MTFRATDSEFDLTNIEEYAENSALSRLNNIKAKQRVSYVTSTENESDTQILTFRHITKAQ 60
MTFRATDSEFDLTNIEEYAENSALSRLNNIKAKQRVSYVTSTENESDTQILTFRHITKAQ
Sbjct: 1 MTFRATDSEFDLTNIEEYAENSALSRLNNIKAKQRVSYVTSTENESDTQILTFRHITKAQ 60
Query: 61 EKTRKRQQPIKLEPLPVLKVYQDHKQPEYIHEQNRFQLMTAGIIKRPVSIAKKSFATSST 120
EKTRKRQQPIKLEPLPVLKVYQDHKQPEYIHEQNRFQLMTAGIIKRPVSIAKKSFATSST
Sbjct: 61 EKTRKRQQPIKLEPLPVLKVYQDHKQPEYIHEQNRFQLMTAGIIKRPVSIAKKSFATSST 120
Query: 121 QFLEHQDAVKKMQIHRPYVEVFSPSPPKLPHTGIGKRGLFGTRSSAYPKYTFHDREEVVK 180
QFLEHQDAVKKMQIHRPYVEVFSPSPPKLPHTGIGKRGLFGTRSSAYPKYTFHDREEVVK
Sbjct: 121 QFLEHQDAVKKMQIHRPYVEVFSPSPPKLPHTGIGKRGLFGTRSSAYPKYTFHDREEVVK 180
Query: 181 ANIRDPLQIIKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRA 240
ANIRDPLQIIKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRA
Sbjct: 181 ANIRDPLQIIKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRA 240
Query: 241 VTHIYNEDIEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKS 300
VTHIYNEDIEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKS
Sbjct: 241 VTHIYNEDIEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKS 300
Query: 301 LQKNLFIVNPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERL 360
LQKNLFIVNPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERL
Sbjct: 301 LQKNLFIVNPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERL 360
Query: 361 GEFRNEAKYVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPTYGDSE 420
GEFRNEAKYVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPTYGDSE
Sbjct: 361 GEFRNEAKYVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPTYGDSE 420
Query: 421 KMTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVI 480
KMTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVI
Sbjct: 421 KMTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVI 480
Query: 481 QKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA 540
QKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA
Sbjct: 481 QKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA 540
Query: 541 VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI 600
VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI
Sbjct: 541 VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI 600
Query: 601 KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDA 660
KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDA
Sbjct: 601 KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDA 660
Query: 661 VALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKL 720
VALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKL
Sbjct: 661 VALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKL 720
Query: 721 EFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMK 780
EFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMK
Sbjct: 721 EFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMK 780
Query: 781 PSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDK 840
PSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDK
Sbjct: 781 PSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDK 840
Query: 841 IRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWD 900
IRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWD
Sbjct: 841 IRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWD 900
Query: 901 KLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVI 960
KLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVI
Sbjct: 901 KLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVI 960
Query: 961 IDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAA 1020
IDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAA
Sbjct: 961 IDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAA 1020
Query: 1021 LEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPL 1080
LEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPL
Sbjct: 1021 LEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPL 1080
Query: 1081 KTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKE 1140
KTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKE
Sbjct: 1081 KTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKE 1140
Query: 1141 IMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDEL 1200
IMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDEL
Sbjct: 1141 IMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDEL 1200
Query: 1201 LEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSP 1260
LEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSP
Sbjct: 1201 LEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSP 1260
Query: 1261 EGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQV 1320
EGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQV
Sbjct: 1261 EGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQV 1320
Query: 1321 ILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTA 1380
ILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTA
Sbjct: 1321 ILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTA 1380
Query: 1381 LITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLG 1440
LITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLG
Sbjct: 1381 LITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLG 1440
Query: 1441 ACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSD 1500
ACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSD
Sbjct: 1441 ACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSD 1500
Query: 1501 GLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGR 1560
GLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGR
Sbjct: 1501 GLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGR 1560
Query: 1561 EIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKI 1620
EIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKI
Sbjct: 1561 EIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKI 1620
Query: 1621 LARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSN 1680
LARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSN
Sbjct: 1621 LARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSN 1680
Query: 1681 LPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFY 1740
LPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFY
Sbjct: 1681 LPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFY 1740
Query: 1741 ETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGE 1800
ETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGE
Sbjct: 1741 ETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGE 1800
Query: 1801 LYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLC 1860
LYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLC
Sbjct: 1801 LYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLC 1860
Query: 1861 LANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKL 1920
LANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKL
Sbjct: 1861 LANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKL 1920
Query: 1921 TEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAM 1980
TEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAM
Sbjct: 1921 TEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAM 1980
Query: 1981 EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHM 2040
EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHM
Sbjct: 1981 EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHM 2040
Query: 2041 DFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGV 2100
DFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGV
Sbjct: 2041 DFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGV 2100
Query: 2101 GKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIV 2160
GKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIV
Sbjct: 2101 GKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIV 2160
Query: 2161 IFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRN 2220
IFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRN
Sbjct: 2161 IFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRN 2220
Query: 2221 PVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKM 2280
PVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKM
Sbjct: 2221 PVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKM 2280
Query: 2281 SVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINN 2340
SVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINN
Sbjct: 2281 SVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINN 2340
Query: 2341 EDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTAN 2400
EDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTAN
Sbjct: 2341 EDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTAN 2400
Query: 2401 VLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLA 2460
VLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLA
Sbjct: 2401 VLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLA 2460
Query: 2461 AHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINN 2520
AHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINN
Sbjct: 2461 AHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINN 2520
Query: 2521 ILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSP 2580
ILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSP
Sbjct: 2521 ILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSP 2580
Query: 2581 VGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVN 2640
VGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVN
Sbjct: 2581 VGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVN 2640
Query: 2641 VHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLL 2700
VHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLL
Sbjct: 2641 VHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLL 2700
Query: 2701 ETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAE 2760
ETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAE
Sbjct: 2701 ETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAE 2760
Query: 2761 ETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLN 2820
ETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLN
Sbjct: 2761 ETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLN 2820
Query: 2821 AKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKS 2880
AKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKS
Sbjct: 2821 AKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKS 2880
Query: 2881 MCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEY 2940
MCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEY
Sbjct: 2881 MCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEY 2940
Query: 2941 DKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAA 3000
DKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAA
Sbjct: 2941 DKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAA 3000
Query: 3001 ACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDL 3060
ACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDL
Sbjct: 3001 ACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDL 3060
Query: 3061 ISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGL 3120
ISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGL
Sbjct: 3061 ISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGL 3120
Query: 3121 PVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLP 3180
PVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLP
Sbjct: 3121 PVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLP 3180
Query: 3181 EVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKIL 3240
EVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKIL
Sbjct: 3181 EVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKIL 3240
Query: 3241 RMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSV 3300
RMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSV
Sbjct: 3241 RMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSV 3300
Query: 3301 MYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSR 3360
MYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSR
Sbjct: 3301 MYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSR 3360
Query: 3361 GLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFA 3420
GLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFA
Sbjct: 3361 GLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFA 3420
Query: 3421 CCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAH 3480
CCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAH
Sbjct: 3421 CCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAH 3480
Query: 3481 QDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNT 3540
QDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNT
Sbjct: 3481 QDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNT 3540
Query: 3541 PLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN 3600
PLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN
Sbjct: 3541 PLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN 3600
Query: 3601 CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL 3660
CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL
Sbjct: 3601 CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL 3660
Query: 3661 RANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSD 3720
RANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSD
Sbjct: 3661 RANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSD 3720
Query: 3721 RECALLNLKLYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEED 3780
RECALLNLKLYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEED
Sbjct: 3721 RECALLNLKLYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEED 3780
Query: 3781 YKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILE 3840
YKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILE
Sbjct: 3781 YKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILE 3840
Query: 3841 VQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQ 3900
VQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQ
Sbjct: 3841 VQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQ 3900
Query: 3901 EVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPL 3960
EVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPL
Sbjct: 3901 EVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPL 3960
Query: 3961 GSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKY 4020
GSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKY
Sbjct: 3961 GSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKY 4020
Query: 4021 SVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDA 4080
SVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDA
Sbjct: 4021 SVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDA 4080
Query: 4081 LPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKR 4140
LPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKR
Sbjct: 4081 LPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKR 4140
Query: 4141 SKDYWIAKGSALLCQLSE 4158
SKDYWIAKGSALLCQLSE
Sbjct: 4141 SKDYWIAKGSALLCQLSE 4158
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 2708 bits (7019), Expect = 0.0
Identities = 1509/3812 (39%), Positives = 2246/3812 (58%), Gaps = 234/3812 (6%)
Query: 436 RLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVIQKWITE--EKPEVPD 493
+L + L Y++++T+ L +++ S ++D + W + P P
Sbjct: 595 KLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPR 654
Query: 494 KKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPN 553
K P+F+ +L+L + + LE F +L + +VP
Sbjct: 655 KN---------------PLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQ 699
Query: 554 LVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARI 613
L D F S P L +V + ++ +++ TI +A A I
Sbjct: 700 LEKLVMEDIFISG-------------DPLLESVGLHEP----LVEELRATIASAVSKAMI 742
Query: 614 ----YAATFEKF--------QIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAV 661
YA + K+ F K ++ L A +++E + E K+ D+
Sbjct: 743 PLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLRE------KEILDS- 795
Query: 662 ALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLE 721
+L + +G I+T +++ L + +L + K+VD+I E + K+
Sbjct: 796 SLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIY 855
Query: 722 FVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFA---VFAT 778
P + E ++ I ER+ LE+ V Y++M+++ +DF + +
Sbjct: 856 EKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASN 915
Query: 779 MKPSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQ 838
I+ + + + E ++ + D ++ ++L I +
Sbjct: 916 WPSKILGQIELVQQQHVEDEEKFRKIQI---MDQNNFQEKLEGLQLVVAG---FSIHVEI 969
Query: 839 DKIRLILNNLQSV---LADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDS 895
+ I N ++ V L D Q+ A Y + ++ F + ++ ++ L + E + LW +
Sbjct: 970 SRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTT 1029
Query: 896 FSEWDKLQQEWLKSKFDCLDPEVLNGQVSK----YAKFVTQLEKGLPPNSVVPQLKYKVE 951
S+W + + W+ +D E L V + K V Q + V ++ ++E
Sbjct: 1030 ASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIE 1089
Query: 952 KMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDI 1011
+ K +P+I LRNP ++ RHW + ++ V + LT R ++++ D + I +
Sbjct: 1090 EFKPYIPLIQGLRNPGMRIRHWETLSNQININ-VRPKANLTFARCLEMNLQDHIESISKV 1148
Query: 1012 SGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATL 1071
+ A E A+E L K+E W T F +LP++ + D +IL D+ LLDD + +
Sbjct: 1149 AEVAGKEYAIEQALDKMEKEWSTILFNVLPYK-ATDTYILKSPDEASQLLDDHIVMTQNM 1207
Query: 1072 ASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMF 1131
+ S Y P + R++ W+ +L L + LEEWL CQR+WLYLE IF++ DI +QLP E+K +
Sbjct: 1208 SFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRY 1267
Query: 1132 LQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPR 1191
+++ WK+IM+ + + +L++ ++ N +LD +QK L YLE+KR FPR
Sbjct: 1268 QTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPR 1327
Query: 1192 FYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYT 1251
FYFLS+DELLEIL+QT++P AVQPHLRKCF++I++L F
Sbjct: 1328 FYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQ-------------------ED 1368
Query: 1252 NDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDW 1311
+I M S EGE V L + NVE+WL +VE +M S+ + + AI Y RT W
Sbjct: 1369 LEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQW 1428
Query: 1312 VVAGHPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLP 1371
V+ P QV + Q W ++ E LE + + F ++ ++L+ L A+V+G L
Sbjct: 1429 VL-NWPGQVTIAGCQTYWTMEVAEALEAGNLRS----QLFPQL-CQQLSDLVALVRGKLS 1482
Query: 1372 KLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQ 1431
++ R +L+ALI I+VHA+D+V++L+Q V +V F W QLRYYW + + R ++
Sbjct: 1483 RMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNN--DLYIRAVNAE 1540
Query: 1432 YTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAI 1491
+ YGYEYLG RLVITPLTDRCYL L GAL L GGAPAGPAGTGKTETTKDL KALAI
Sbjct: 1541 FIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAI 1600
Query: 1492 QCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAK 1551
Q VVFNCSD LD+ MG+FF GLA +GAW CFDEFNRIDIEVLSV+AQQ+ TI+ A+ +
Sbjct: 1601 QTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQR 1660
Query: 1552 LSRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILY 1611
+ RFMFEG EI LV +CA FITMNPGYAGRTELPDNLKALFRP AMMVP+YA+I E+ LY
Sbjct: 1661 VERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLY 1720
Query: 1612 SEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVV 1671
S GF + +LA+K+T +KL SEQLS QDHYDFGMRAVK+V+ AG+LKRENP +NE+++
Sbjct: 1721 SFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELI 1780
Query: 1672 LIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMC 1731
+RA++D N+PKFL +D LFSGI+SDLFP ++ + DYGIL I + NL+
Sbjct: 1781 CLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEG 1840
Query: 1732 MVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQ-KLGIENSFYQAVKTYV 1790
+ K IQ YET +VRHG+MLVGPTG GK+T YR+LA + +L+ + I Y+AV YV
Sbjct: 1841 FLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYV 1900
Query: 1791 LNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMN 1850
LNPKSITMG+LYGE + LT EW DG+ + +RA + + KW + DGPVDA+WIENMN
Sbjct: 1901 LNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMN 1960
Query: 1851 TVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVK 1910
TVLDDNK LCL++ E IKLT + M+FEVQDL VASPATVSRCGMV+++P L MP+++
Sbjct: 1961 TVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIE 2020
Query: 1911 TWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLI 1970
W++ + L + +E+ LF +++E + F+ + I + + +L LL+
Sbjct: 2021 CWLRKLPP-LLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFF 2079
Query: 1971 ---LGKDGVNLAMEQ--TKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNP 2025
L ++G+ + +++ ++ F+F +WS+G + SF ++R + ++
Sbjct: 2080 KPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQ 2139
Query: 2026 -----------------DARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEM 2068
DA + + D ++ W F D + +
Sbjct: 2140 LTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNI 2199
Query: 2069 LVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSV-IAKGLLNKIQESAGYVPVYLNFS 2127
+VPT DTV+ +L++ LL K VL G TG GK++ I+ LL + + Y+ +L FS
Sbjct: 2200 IVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNL--ALDYISHFLTFS 2257
Query: 2128 AQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQ 2187
A+TS+ +TQ+ I+SKL+++RK + G P + + F+DDLNMP L+ YG+QPPIELLRQ+
Sbjct: 2258 ARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWM 2317
Query: 2188 DFGGFYDRNKL-FWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQI 2246
D GG+YDR + +K + D+ + A PPGGGRN VTPR +RHF+ L E S K+I
Sbjct: 2318 DHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRI 2377
Query: 2247 FQAILNGFLSDF------------PPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYV 2294
F IL +L P + +VEA++ +Y ++ LLPTPAKSHY
Sbjct: 2378 FSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYT 2437
Query: 2295 FNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMA 2354
FNLRDLSK QG+L DP + +++Q+ RL+ HE RVF DRL+N ED+ +F +L
Sbjct: 2438 FNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCM 2497
Query: 2355 NKHFGIAIDLEYFLNK-----PIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDY 2409
+ E NK PI++GDF+ G+D + Y+ + K V+++Y++DY
Sbjct: 2498 EQW-------EVTFNKVCPFQPILYGDFMSPGSDV--KSYELITSESKMMQVIEEYIEDY 2548
Query: 2410 NLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCL 2469
N N ++KLV F DA+ H+ RI+R +RQ GNALL+GVGG+G+ SLTRLA+H+ Y+C
Sbjct: 2549 NQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECF 2608
Query: 2470 QIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPN 2529
QIELS+ Y + +D++K+ AG+++ + FLF+DTQI E FLEDINN+LNSG++PN
Sbjct: 2609 QIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPN 2668
Query: 2530 LFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRC 2589
L+ DE +Q+++ RP +E G+ + + + + +VR +H+VLCMSP+GE FR+R
Sbjct: 2669 LYTADEQDQIVSTMRPYIQEQGL-QPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARL 2727
Query: 2590 RMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQV---DAGNEELKEKLPLMCVNVHLSVS 2646
R FPSLVNCCTIDWF +WP EAL SV+ F +++ ++ EE+ + L +CV +H SVS
Sbjct: 2728 RQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEI-QGLIQVCVYIHQSVS 2786
Query: 2647 SMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILV 2706
Y EL R Y TP SYLEL++++ ++ +K+ ++ +A++R+K+GL KLL T+ V
Sbjct: 2787 KKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDV 2846
Query: 2707 DKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIA 2766
KM+ DL ++ P+L ++D ME++ VD A++ RN+VQ +E A KA++ QAIA
Sbjct: 2847 AKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIA 2906
Query: 2767 DDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPD-- 2824
DDAQ+DLDEALPALDAA +L +L+K D++E+R +PP V V+EA+ I+ KP
Sbjct: 2907 DDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKV 2966
Query: 2825 ------------WPSAKQLLGD-SNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKV 2871
W K LL D +FL+ L ++DK+NI ++ +Q YI+N +F P +
Sbjct: 2967 PGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATI 3026
Query: 2872 EKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVED 2931
KVSKAC S+C WVRAM Y V K VEPKRQ L AQ +L +T L E + LR+VED
Sbjct: 3027 AKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVED 3086
Query: 2932 QIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISN 2991
I +Q +Y + + +KE L + RL RAGKL L DE+VRW+E+++ + ++N
Sbjct: 3087 GIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNN 3146
Query: 2992 ITGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQW 3051
I+G+V +AA VAY G FT QYR L + W++ +S +P +LI LG+P +IR W
Sbjct: 3147 ISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSW 3206
Query: 3052 NTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRI 3111
GLP D +S ENG++ +RW IDPQ QAN+WI+N E +GL + KL+D +FLR
Sbjct: 3207 QIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRS 3266
Query: 3112 LENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTT 3171
+EN+IR G P LLE + E LDPALEP+LLKQ + G +++LGD+ I Y ++FR Y+TT
Sbjct: 3267 MENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITT 3326
Query: 3172 KMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQ 3231
K+PNPHY PE+ K+T+INFT++ SGLEDQLL VV E+P LEE + +LI+ + +
Sbjct: 3327 KLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQE 3386
Query: 3232 LKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKY 3291
LK IE++IL L +SEGN +D+ ELI L+ SK+ + I+ ++ AE TE+ I++ R +Y
Sbjct: 3387 LKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEY 3446
Query: 3292 RPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTL 3351
PVA + +++F ++ L+ +DPMYQYSL++F +F + I S + +NL++R+ +
Sbjct: 3447 IPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLT 3506
Query: 3352 LTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAP 3411
+ Y NV R LFE+HKL+++F+LCV +M +G ++ +EW + L G + P P+
Sbjct: 3507 YSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPD-- 3564
Query: 3412 WLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKH 3471
WL W L + P F + + + H L F + +
Sbjct: 3565 WLSDRAWRDILAL-SNLPTFSSFSSDFVKH-----LSEFRVIFDSLE------------- 3605
Query: 3472 MRQEKEAAHQDP----WSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPV 3527
H++P W L F KL++++C + +KV A+ DFV NL +FIE
Sbjct: 3606 -------PHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTA 3658
Query: 3528 DLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVK 3587
+L +++D + TPL+F+LS G+DP +FA E +S+++ +ISLGQGQGP AE M++
Sbjct: 3659 NLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMR 3718
Query: 3588 DAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQ 3647
+++ G WVF QNCHLA SWM A+E LI+ +PD +D FRL+L+S+PSN FPV++LQ
Sbjct: 3719 SSIERGKWVFFQNCHLAPSWMPALERLIE-HINPDKVHRD-FRLWLTSLPSNKFPVSILQ 3776
Query: 3648 NSVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGP 3707
N K+T EPP+G+RAN+ ++++ + F +++ ++ +C FH ER+KFGP
Sbjct: 3777 NGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGP 3836
Query: 3708 LGWNICYEFNDSDRECALLNLKLYCKE-GKIPWDALIYITGEITYGGRVTDSWDQRCLRT 3766
LG+NI YEF D D + LK++ E IP+ L Y GEI YGGRVTD WD+RC+
Sbjct: 3837 LGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMN 3896
Query: 3767 ILKRFFSPETLEEDYKYSESGIYF-APMADSLQEFKDYIENLPLIDDPEIFGMHENANLV 3825
IL+ F++P+ L ++ YS SGIY P L + YI++LPL D PEIFG+H+NAN+
Sbjct: 3897 ILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANIT 3956
Query: 3826 FQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVK 3885
F ET L+ TI+++QP+SS+ G + +EIV+++ ++ +VPE + ++ V
Sbjct: 3957 FAQNETFALLGTIIQLQPKSSSAG-SQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVL 4015
Query: 3886 DLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQV 3945
+ S+ TVL QEV R+N LL++I +L+ L KA+ G VVMS ++E + S NN V
Sbjct: 4016 YEE----SMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTV 4071
Query: 3946 PALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNH 4005
P LWS AYPSLKPL SWV DL+ R F+ W++ G P +WISGFFFPQ FLTGTLQN
Sbjct: 4072 PELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNF 4131
Query: 4006 ARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFM 4065
ARK+ + ID +SF + V+ E P ++ P+ G +HG+F+
Sbjct: 4132 ARKFVISIDTISFDFKVM-------------------FEAPSEL-TQRPQVGCYIHGLFL 4171
Query: 4066 DASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTLSTT 4124
+ +RWD + + ++ P ++ + V+ P N K Y CP+YKT RAGTLSTT
Sbjct: 4172 EGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTT 4231
Query: 4125 GHSTNFVVTVLLPSKRSKDYWIAKGSALLCQL 4156
GHSTN+V+ V +P+ + + +WI +G AL+C L
Sbjct: 4232 GHSTNYVIAVEIPTHQPQRHWIKRGVALICAL 4263
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 2631 bits (6819), Expect = 0.0
Identities = 1491/3738 (39%), Positives = 2180/3738 (58%), Gaps = 205/3738 (5%)
Query: 511 PMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINN 570
P F+ L+L ++ FEP L D++D L + V VP + Y +
Sbjct: 400 PGFIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLY----------S 449
Query: 571 KLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATFEKFQIFFKENES 630
K E K+ T + + + H +IKE I + + ++K+
Sbjct: 450 KWESKSKPTTLK-PIILNEIVDAHK--EKIKEVIMKESVAPTEHLRLYDKYDFLITRKAE 506
Query: 631 LDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTR---LLREKLIPSP 687
D+ + +++ KY K ++ + + + L + + L+R + +
Sbjct: 507 RDVDNFLAENHSYEKIIDEICKYQKLIEE-IQYTSIKTIRLGMFEMHCEELIRALVKRAD 565
Query: 688 LRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEIQ-----E 742
+ C ++L M R ++ + E + K P T E + ++ +++ E
Sbjct: 566 IICGKLLAKMF-RDHQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIE 624
Query: 743 RIESLEDEGNIVTQM--YKLMEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKSVGDRESS 800
+ L D N + + Y + F + M R I + + +
Sbjct: 625 LEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEG 684
Query: 801 IKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKRAF 860
+K C +LE + E + D+ K + ILN + AD +
Sbjct: 685 LKLRCERFVEELESYAKQSEEFYSFGD---LQDVQRYLKKAQ-ILNGKLDLAAD---KIE 737
Query: 861 QYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLN 920
Q+ + ++ F S + +++ L L+++ E+ + W + + ++P+ +
Sbjct: 738 QFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVE 797
Query: 921 GQVSKYAKFVTQLEKGLPPN----SVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAI 976
+ Y + + +LEK + ++ +++ KVE K+ +P+I + NP L+ RHW A+
Sbjct: 798 ADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAM 857
Query: 977 EQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTE 1036
V L ++ T+ +++ + + IS AS E +LE ++K+ W E
Sbjct: 858 SAIVGYPLQPSD-DSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVE 916
Query: 1037 FVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQ 1096
FVI +R++ FIL D+IQ+LLDD I T+ S ++ P + ++ EW+ +L L +
Sbjct: 917 FVIHSYRET-GTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQE 975
Query: 1097 TLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAAT 1156
L+EWL Q WLYLE IF++PDI Q+P E + F VDK+W++IMR V + + L T
Sbjct: 976 ILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVT 1035
Query: 1157 QPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPH 1216
+LE + +N LL+ I K L YLE KR+ FPRF+FLSNDELLEIL++T++P VQPH
Sbjct: 1036 IDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPH 1095
Query: 1217 LRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGL---KA 1273
L+KCF+ I+K+EF T DI M S EGE V L + + KA
Sbjct: 1096 LKKCFEGIAKVEFT-------------------ETLDITHMKSSEGEVVELIEIISTAKA 1136
Query: 1274 RGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDL 1333
RG VE+WL ++E M S+ ++ A Y R +WV P Q +L VSQI W +++
Sbjct: 1137 RGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWV-RDWPGQTVLCVSQIFWTKEV 1195
Query: 1334 TECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVT 1393
+T I+AL+ + K +++ + +V+G L +R L AL+ +DVHARD+++
Sbjct: 1196 ----QTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLS 1251
Query: 1394 ELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDR 1453
LV+ + F+W QLRYYW + + +M + YGYEYLG PRLVITPLTDR
Sbjct: 1252 SLVKKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDR 1309
Query: 1454 CYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSG 1513
CY L GAL L LGGAP GPAGTGKTETTKDLAKA+A QCVVFNCSDGLDY +G+FF G
Sbjct: 1310 CYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKG 1369
Query: 1514 LAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFIT 1573
L GAW CFDEFNRID+EVLSV+AQQ++TI+ A MFEG E+KL TCA FIT
Sbjct: 1370 LLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFIT 1429
Query: 1574 MNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCS 1633
MNPGYAGR+ELPDNLKALFR AMMVP+YA+IAE++LYS GF +++ L+ K+ Y+LCS
Sbjct: 1430 MNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCS 1489
Query: 1634 EQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFS 1693
EQLS Q HYD+GMRAVKSVL AG+LK + P+ NE+++L+R++ D NLPKFL+ D LF
Sbjct: 1490 EQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFE 1549
Query: 1694 GIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVG 1753
GI SDLFPGV++P+ DY L + I D NLQ K++Q YE M+VRHG M+VG
Sbjct: 1550 GITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVG 1609
Query: 1754 PTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWK 1813
GGKT+ YR+LA L ++ + G+ V+ VLNPKS+TMG+LYG+ ++++ EW
Sbjct: 1610 EPFGGKTSAYRVLAGALNDICEKGLMEE--NKVQITVLNPKSVTMGQLYGQFDSVSHEWS 1667
Query: 1814 DGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQI 1873
DG++A+S RA + + D KW+I DGPVDA+WIENMNTVLDDNK LCL + E I+++PQ+
Sbjct: 1668 DGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQM 1727
Query: 1874 HMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQ 1933
+++FE DL VASPATVSRCGM++++P L W P + +W+ + ++ +E+I+ LF
Sbjct: 1728 NLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFD 1787
Query: 1934 RYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILG-KDGVNLAMEQTKLNTILCQ- 1991
R V + FI K + P D + V +L L++ + D V L + L +
Sbjct: 1788 RMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEG 1847
Query: 1992 TFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWS-------------- 2037
F+F +WS+G + T++ F+ +R + R N+ L S
Sbjct: 1848 IFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPF 1907
Query: 2038 ------IHMDFDTKRLDPWERIIPTFK----YNRDVPFFEMLVPTTDTVRYGYLMEKLLA 2087
F T+ + WE I K +DV F E++VPT DT+RY LME L
Sbjct: 1908 PEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTT 1967
Query: 2088 VKHSVLFTGITGVGKSV-IAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERK 2146
+ +F G TG GKSV I LLN++ + Y P+ +NFSAQT++A+TQ I+ SKL+++
Sbjct: 1968 HQKPSIFVGPTGTGKSVYITNFLLNQLNKEI-YKPLLINFSAQTTAAQTQNIVMSKLDKR 2026
Query: 2147 RKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDV 2206
RK + G P KR+V+FVDD+NMP + YG+QPPIELLRQ+ D +YD ++ D+
Sbjct: 2027 RKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDI 2086
Query: 2207 TIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLS---DFPPAVK 2263
I+ A PPGGGRNPVTPR++RHF+++ + S+ S+ IF IL L FP
Sbjct: 2087 QIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFL 2146
Query: 2264 QTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFR 2323
+ IV ++ +Y + +LLPTPAKSHY+FNLRD S+ +QG+ P T I R
Sbjct: 2147 DLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKR 2206
Query: 2324 LFCHECQRVFHDRLINNEDK----HYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIK 2379
L+ HE RV++DRL++N D+ +Y IL + F F N ++ D ++
Sbjct: 2207 LWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLR 2266
Query: 2380 -------FGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRI 2432
+ D Y ++ D++ +++ +L++YN + K + LV F+ AIEH+SRI
Sbjct: 2267 SLMFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRI 2326
Query: 2433 ARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKM 2492
+R+++Q R +ALLVGVGG+G+QS+TRLAAH+ Y Q+E+S+GY+ +HEDL+ + +
Sbjct: 2327 SRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRK 2386
Query: 2493 AGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQV------LAATRPR 2546
+ VFLFTDTQI E FLED++N+LN+GE+PNLF DE +++ L R +
Sbjct: 2387 CAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDK 2446
Query: 2547 AKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQ 2606
K+ ++G+ +F FI R +LH+VL MSP+G+AFR+R R FP+LVNCCTIDWF
Sbjct: 2447 TKQ---TDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQS 2503
Query: 2607 WPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTS 2666
WP +AL +V+ F +++ +EE+++ MC + H S +++ ++ EL+R Y TPTS
Sbjct: 2504 WPEDALQAVASRFLEEIEM-SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTS 2562
Query: 2667 YLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSED 2726
YLELI+ + +L +KR +++ + R + GL KL + V M+++L AL P L S++
Sbjct: 2563 YLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKE 2622
Query: 2727 VEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKA 2786
V+ +M + + + V+ DE A +A ++AI D+ DL ALP L++A A
Sbjct: 2623 VDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAA 2682
Query: 2787 LDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPD---------------WPSAKQL 2831
LD+L DI+ ++ PP V VMEAI IL K D W AK+L
Sbjct: 2683 LDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRL 2742
Query: 2832 LGDSNFLKRLLEYDKENIKPQILAKLQK-YINNPDFVPEKVEKVSKACKSMCMWVRAMDL 2890
LGD FL+ L EYDK+NI P + ++K YI NPDFVPEK+ S A + +C WV AMD
Sbjct: 2743 LGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDS 2802
Query: 2891 YSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESL 2950
Y +V K+V PK+ KL AA+ EL I M LR+KQA L++V+D++ LQD + +K L
Sbjct: 2803 YDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADL 2862
Query: 2951 AKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFT 3010
+ L +L RA +L L E+ RW + + + N+TG++ I++ VAY GAFT
Sbjct: 2863 ENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFT 2922
Query: 3011 AQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVT 3070
+ YRQ+ + W C+ +IP SL+ LG+ IR WN GLP D S +NGI++
Sbjct: 2923 STYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIM 2982
Query: 3071 QGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKET 3130
RRWPLMIDPQ QAN+WI+N E + L +IKL++ +++R LEN I+ G PVLLE + E
Sbjct: 2983 NARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEE 3042
Query: 3131 LDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIIN 3190
LDP LEP+LLKQ F GG IRLGDS I+Y +FRFY+TTK+ NPHYLPE +KVT++N
Sbjct: 3043 LDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLN 3102
Query: 3191 FTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNI 3250
F +T G++DQLL VV E+P LEE++ LI++ +K QLK IE+KIL +L +SEGNI
Sbjct: 3103 FMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNI 3162
Query: 3251 LDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSE 3310
L++E I L SK + I + E AE TE+ I+ R YRP+A S+++F +A L+
Sbjct: 3163 LEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLAN 3222
Query: 3311 IDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIY 3370
I+PMYQYSL +F LF +IE S K+E L +RL +L + + YVNV R LFE+ KL++
Sbjct: 3223 IEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLF 3282
Query: 3371 SFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPV 3430
SF L + ++ + ++ AEW F L G GL + P WLP +W C L++ P
Sbjct: 3283 SFCLTINLLLHERAINKAEWRFLLTGGIGL--DNPYANLCTWLPQKSWDEICRLDD-LPA 3339
Query: 3431 FHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQ---DPWSAG 3487
F + + + ++K K + E H+ + W
Sbjct: 3340 FKTIRRE------------------------FMRLKDGWKKVYDSLEPHHEVFPEEWEDK 3375
Query: 3488 LSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILS 3547
+ F ++++I+C + +KV+ L +F+I LG+ FIE PP DL + D +C PL+F+LS
Sbjct: 3376 ANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLS 3435
Query: 3548 TGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVS 3606
G+DPM A +FA + GY ++ S+SLGQGQGPIA KM++ A+K G WV LQNCHLA S
Sbjct: 3436 PGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATS 3495
Query: 3607 WMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRR 3666
WM +E++ + + P+S D FR++L+S PS FPV+VLQN VK+TNE PKGLRANI R
Sbjct: 3496 WMPTLEKVCEELS-PESTHPD-FRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIR 3553
Query: 3667 AFTE---MTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDREC 3723
++ P FF ++++++++G+CFFHA++QER+KFGPLGWNI YEFN++D
Sbjct: 3554 SYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRI 3613
Query: 3724 ALLNLKLYCKE-GKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLE-EDY 3781
++ L ++ + ++P++AL Y+TGE YGGRVTD WD+R LR+IL +FF+PE +E DY
Sbjct: 3614 SVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDY 3673
Query: 3782 KYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEV 3841
K+ SGIYF P + + + +Y + LPL PEIFGM+ NA++ ET L + IL
Sbjct: 3674 KFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLT 3733
Query: 3842 QPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQE 3901
Q RS+ G KS+DE+V E+ + + ++P ++E A Q S+ TVL QE
Sbjct: 3734 QSRSA-GAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQ----SMNTVLVQE 3788
Query: 3902 VDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLG 3961
+ RFN LLK I S + KAI G VMS ++E+V +S LN ++P +W +YPSLKPLG
Sbjct: 3789 MGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLG 3848
Query: 3962 SWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYS 4021
S+V D + R F+ W + G P +W+SGFFF Q FLTG QN+ARKY +PID L F Y
Sbjct: 3849 SYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYE 3908
Query: 4022 VIPTYRDQAAVIEAAKTVQFGQELPMDMELP-SPEDGVLVHGMFMDASRWDDKEMVIEDA 4080
V+ D E PEDGV +HG+F+D + W+ K + ++
Sbjct: 3909 VME-----------------------DKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAES 3945
Query: 4081 LPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSK 4139
P + +PV+ +P + P Y PLYKT R G LSTTGHSTNFV+ + LPS
Sbjct: 3946 HPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSD 4005
Query: 4140 RSKDYWIAKGSALLCQLS 4157
+ K++WI +G ALLCQL+
Sbjct: 4006 QPKEHWIGRGVALLCQLN 4023
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 2597 bits (6732), Expect = 0.0
Identities = 1427/3666 (38%), Positives = 2190/3666 (59%), Gaps = 137/3666 (3%)
Query: 516 ELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGK 575
+L +V + F P+L+ + NH +T+ S F KL +
Sbjct: 872 DLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTI---------SVFCHLPDILTKRKLHRE 922
Query: 576 TCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATFEKFQIFFKENESLDLQA 635
T V E D++ I +QI + + Y T++ ++ ++ N+ +
Sbjct: 923 PIQT------VVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHR 976
Query: 636 LKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLN 695
+ P ++ F + +Y + + N+ +L+D L+ L+ C E N
Sbjct: 977 YQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQ---HCNEWQN 1033
Query: 696 ----FMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEG 751
+ + + ++ + ++AE K+ P T E SL +D ++ + ++E +
Sbjct: 1034 KFATLLREMAAGRLLELHTYLKENAE-KISRPPQTLEELGVSLQLVDALKHDLANVETQI 1092
Query: 752 NIVTQMYKLMEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKS---VGDRESSIKQFCVHL 808
+ + + ++E+Y+VP + ++ V + + S + + K +H
Sbjct: 1093 PPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHS 1152
Query: 809 GSDLEE-LNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKRAFQYKSYQK 867
D ++ + + + + + + + D+I ++++L +++ ++
Sbjct: 1153 ADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQI----TQVRAMLMAMREEENSLRANLG 1208
Query: 868 NFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQVSKYA 927
FK+E + L+ + EL Q +W+ +W++ EW +F L E +
Sbjct: 1209 IFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLF 1268
Query: 928 KFVTQLEKGLPPNS--VVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLV 985
+ +T+L K + ++ + K+E+ K +P+I DLRNP L+ RHW + +
Sbjct: 1269 RRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFD 1328
Query: 986 DAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFVILPHRDS 1045
TLE++ +L + ++I +IS A+ E A+E L+ + +W T+ I+P++D
Sbjct: 1329 QESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKD- 1387
Query: 1046 KDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQ 1105
K L GT+++ L+D+ + ++T+ +SR++ + VD W++ L+L + +E LT Q
Sbjct: 1388 KGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQ 1447
Query: 1106 RNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQ 1165
R W+YLE+IF DI++QLP E+ +F QV+ +WK IM ++N+ NALR+ PGLL+T
Sbjct: 1448 RQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLI 1507
Query: 1166 NNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSIS 1225
N +L+ IQK L+ YLE+KR IFPRFYFLSND+LLEIL Q+RNP+AVQPHL+KCFD+I
Sbjct: 1508 EMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIK 1567
Query: 1226 KLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVE 1285
L K+ G + E V M S +GE + + G VE WLG VE
Sbjct: 1568 LLRIQ-------KVGGPSSKWEAV------GMFSGDGEYIDFLHSVFLEGPVESWLGDVE 1614
Query: 1286 EAMFTSLRRL---CKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECLETEHS 1342
+ M +LR L C A+ + K R WV QV++T SQI W D+T+CL T
Sbjct: 1615 QTMRVTLRDLLRNCHLALRKFLNK-RDKWVKEW-AGQVVITASQIQWTADVTKCLLTAKE 1672
Query: 1343 N-HIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSKVE 1401
+ LK +K LN + ++G+L K+ R + AL+TI++HARD++ +L +S +
Sbjct: 1673 RADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLM 1732
Query: 1402 TVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGA 1461
V SFDW QLR+YW+ DLD+CV R +Q+ Y YEYLG RLVITPLTDRCY+ L A
Sbjct: 1733 DVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTA 1792
Query: 1462 LQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWC 1521
L L GG+P GPAGTGKTET KDL KAL I +V NCS+GLDYK MGR +SGLAQ+GAW
Sbjct: 1793 LHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWG 1852
Query: 1522 CFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPGYAGR 1581
CFDEFNRI+IEVLSV+A Q++ I +A AA L+ F F+G EI LV +C FITMNPGYAGR
Sbjct: 1853 CFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGR 1912
Query: 1582 TELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDH 1641
TELP+NLK++FRP AM+VP+ LIAE+IL+ EGF + KILA+K+ +Y L +QLS+QDH
Sbjct: 1913 TELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDH 1972
Query: 1642 YDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDLFP 1701
YDFG+RA+ S+L AG +R PDL ++ VL+ +++D N+ K + DA LF+ I+ DLFP
Sbjct: 1973 YDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFP 2032
Query: 1702 GVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTT 1761
+++P DYG L+ T+ + LQ + KV Q YET RH M+VG TG GKT
Sbjct: 2033 NIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTA 2092
Query: 1762 VYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSV 1821
+RIL +L +L + G N + V+ + LNPK++++GELYGE + T EW DG+++ +
Sbjct: 2093 SWRILQASLSSLCRAGDPN--FNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVM 2150
Query: 1822 RAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQD 1881
R A D D KWI+ DGPVD LWIENMN+V+DDNK+L L N ERI + Q+ +LFEV+D
Sbjct: 2151 RTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVED 2210
Query: 1882 LRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLH 1941
L +ASPATVSRCGMV+ D +L W PYV++W++ K E Q +F++ +++ L
Sbjct: 2211 LAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQ----RMFEKLINKMLA 2266
Query: 1942 FINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCYLWSL 2001
F C + +P + S +T+LC L +L ++GVN A + + T++ TFVF +WS+
Sbjct: 2267 FKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPADGENYV-TMVEMTFVFSMIWSV 2325
Query: 2002 GGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIP-TFKYN 2060
++ E D+++R + PN ++ +D + +E +P +++Y
Sbjct: 2326 CASVDEEGRKRIDSYLR-----EIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYP 2380
Query: 2061 RDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYV 2120
+ PF++++VPT DTVRY YL+ L+A ++ +L G G GK+ IA+ +L + S V
Sbjct: 2381 PNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSV 2440
Query: 2121 PVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPI 2180
V +N SAQT+S Q IIES++E++ K + G K ++ F+DDLNMP D +GSQPP+
Sbjct: 2441 LV-VNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPL 2499
Query: 2181 ELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSE 2240
EL+R + D+G +YDR K K I+++ +++A PPGGGR ++PR F+++ + P++
Sbjct: 2500 ELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTK 2559
Query: 2241 HSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDL 2300
+ +IF ++N L DF VK + + EA++++YN + LPTP K HY+FNLRD+
Sbjct: 2560 SQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDI 2619
Query: 2301 SKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGI 2360
SK QG+L+ + + I RL+ HEC RVF DRL++ D F I+++ F +
Sbjct: 2620 SKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDL 2679
Query: 2361 AIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLT-NPKEVKL 2419
+P IFGDF+ K ++Y+D+ D+ V++ L++YNL+ + ++L
Sbjct: 2680 TFHHLCPSKRPPIFGDFL-----KEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQL 2734
Query: 2420 VFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNY 2479
V F++AIEH++RI R+I Q RGN LLVG+GG+G+QSL RLA+ IC Y QIE+++ Y
Sbjct: 2735 VLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRK 2794
Query: 2480 DSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQV 2539
F +D+++LY+ AGVE K F+F DTQI E FLEDINNIL+SGEVPNL++ DE E++
Sbjct: 2795 QEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEI 2854
Query: 2540 LAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCC 2599
+ +A+ + E + D +F Y I +V+ LHIVLC+SP+G+ FR+ R +P+LVNC
Sbjct: 2855 QSHIIDQARVEQVPESS-DSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCT 2913
Query: 2600 TIDWFVQWPREALLSVSKTFFSQVDAGNEE-LKEKLPLMCVNVHLSVSSMAERYYNELRR 2658
TI+WF +WP+EALL V++ VD G +E + K+ + V +H SV+ +++ ELRR
Sbjct: 2914 TINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRR 2973
Query: 2659 RYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEP 2718
Y TPT YLEL++ Y +L EKR+++++ ++++ GL K+ ET V M L+L +
Sbjct: 2974 HNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKK 3033
Query: 2719 VLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALP 2778
+ + E + + + AD+ + V + V+ + QA+AD+AQ+DL+EALP
Sbjct: 3034 KVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALP 3093
Query: 2779 ALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLGDSNFL 2838
AL+ A +AL+SL+K DI EI+ + +PP V VM+A+ IL +P W AK+ LG+ NF+
Sbjct: 3094 ALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFI 3153
Query: 2839 KRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVV 2898
K L+ +DK+NI ++L K+ Y PDF P+ + +VS A KS+CMWVRAM+LY R+ +VV
Sbjct: 3154 KSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVV 3213
Query: 2899 EPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTK 2958
EPKR ++ AA A+L A L E Q LR+V ++++ L+ +YD+ + +KE L K +
Sbjct: 3214 EPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEME 3273
Query: 2959 ARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLI 3018
+L RAG L + L E+ RWEE++Q EE++ + G+ +AAA ++Y G F YR ++
Sbjct: 3274 LKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIV 3333
Query: 3019 -ECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPL 3077
+ WI L++P PSF++ N L +P ++R WN GLP D STENGI+VT+G RW L
Sbjct: 3334 NQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWAL 3393
Query: 3078 MIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEP 3137
MIDPQ QA +WI+N E GLKII L S++LRILE++I G PVLL+ ++E LDP L P
Sbjct: 3394 MIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNP 3453
Query: 3138 ILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSG 3197
+L K + GGRLL+R+GD +++Y+ NFRFY+TTK+ NPHY PE K TI+NF V + G
Sbjct: 3454 MLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQG 3513
Query: 3198 LEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELI 3257
LE QLL VVR E+P LEEQ+ L++ I K +LK +E++ILR+L + G++LD+ +L+
Sbjct: 3514 LEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLV 3573
Query: 3258 DTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQY 3317
+TL SKIT+ + +LE +E+TE ++ARE YRP A + S+++FV+ + IDPMYQ+
Sbjct: 3574 NTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQF 3633
Query: 3318 SLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVE 3377
SL + LF +I+ S ++ L+ R+D L + Y R LFE+HKL++SF +C +
Sbjct: 3634 SLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAK 3693
Query: 3378 MMRQQGTLSDAEWNFFLRGSAGLEKE-RPPKPEAPWLPTATWFACCDLEESFPVFHGLTQ 3436
++ G L+ E+NFFLRG L++E + P + WL A W +L++ FHGL
Sbjct: 3694 ILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDK-LTNFHGL-- 3750
Query: 3437 NILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLIL 3496
+ SFE Y P+ W + +K M + W + ++++
Sbjct: 3751 ----------MNSFEQY--PRDWHLWYTNAAPEKAMLPGE-------WENACNEMQRMLI 3791
Query: 3497 IKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILSTGSDPMGAF 3556
++ ++++V F +T F+I NLG +FIE P +++ ++ +D + +PLVFILS G DP A
Sbjct: 3792 VRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSAL 3851
Query: 3557 QRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIK 3616
+ A G ++R ++SLGQGQ PIA +++++ + G+WVFL NCHL++SWM +++L++
Sbjct: 3852 LQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVE 3911
Query: 3617 TFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFF 3676
D +FRL+LSS+P FP+++LQ S+K+T EPPKGL+AN+ R + M+ F
Sbjct: 3912 QLQVEDP--HPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQF 3969
Query: 3677 EENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKE-G 3735
K+++++F +CFFH+++ ERKKF LGWNI Y FNDSD E + L LY E
Sbjct: 3970 SRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYE 4029
Query: 3736 KIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDY-KYSESGIYFAPMA 3794
+ PWDAL Y+ I YGG VTD WD+R L T + +F ++L + + S YF P
Sbjct: 4030 ETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKD 4089
Query: 3795 DSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPR-SSTGGEGKS 3853
SL +K+YI LP +D PE FG H NA++ Q E TL +T+L +QP+ + T G++
Sbjct: 4090 GSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQT 4149
Query: 3854 NDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIH 3913
+E V EL A V+ ++PE ++ EG + L + + L VL QE+ R+N L++ I
Sbjct: 4150 REEKVLELAADVKQKIPEMIDYEGTQKLLALDP-----SPLNVVLLQEIQRYNTLMQTIL 4204
Query: 3914 TSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSF 3973
SL L K I G +VMS +E+++N + VP LW AYPS KPL +W +DL +R
Sbjct: 4205 FSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGK-AYPSQKPLAAWTRDLAMRVEQ 4263
Query: 3974 VDLWLKRGQPK-SYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAV 4032
+LW R +P +W+SGF FP GFLT LQ+ AR+ N+ +D LS+++ ++ T D V
Sbjct: 4264 FELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEF-IVSTVDDSNLV 4322
Query: 4033 IEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVV 4092
P+DGV V G++++ + WD K + +A P Q+ ++P +
Sbjct: 4323 Y-------------------PPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTI 4363
Query: 4093 HFEPQQNYKPSPT-LYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPS-KRSKDYWIAKGS 4150
HF P ++ K S +Y CP Y RAG + +FV+ + L S + D+WI +G+
Sbjct: 4364 HFRPAESRKKSAKGMYSCPCYYYPNRAG----SSDRASFVIGIDLRSGAMTPDHWIKRGT 4419
Query: 4151 ALLCQL 4156
ALL L
Sbjct: 4420 ALLMSL 4425
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 2551 bits (6613), Expect = 0.0
Identities = 1430/3621 (39%), Positives = 2127/3621 (58%), Gaps = 190/3621 (5%)
Query: 614 YAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLL 673
Y ++K+ ++ A + DI+ F ++ K+ + ++ T + +
Sbjct: 606 YLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVPLAMFC 665
Query: 674 IDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHS 733
+D L L + L ++ +I + K+ VP T E V
Sbjct: 666 LDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSL 725
Query: 734 LLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAV-FATMKPSIVAV----RN 788
+ FL + + ++KL Q + + +F + +A + I + RN
Sbjct: 726 IEFLKK------------SSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSRN 773
Query: 789 AIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNL 848
+ E + + C LE + E+ + + + ++ + +K+ + NL
Sbjct: 774 LLLHKRDQAEMDLIKRCSEFELRLEGYHRELESFR-KREVMTTEEMKHNVEKLNELSKNL 832
Query: 849 QSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLK 908
A+ + + + +K E S + L+ + + LW + E+ +EW+
Sbjct: 833 NRAFAEFELINKEEELLEK----EKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMN 888
Query: 909 SKFDCLDPEVLNGQVSKYAKFVTQLEKGLP----PNSVVPQLKYKVEKMKEKLPVIIDLR 964
L+ E + ++ + +L K L P + +K K++K K+ +P++
Sbjct: 889 GPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISC 948
Query: 965 NPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFG---QEIQDISGQASGEAAL 1021
NP +K RHW I + V + E LS + F FG ++++ I AS E +L
Sbjct: 949 NPGMKDRHWQQISEIVGYEIKPTETTC----LSNMLEFGFGKFVEKLEPIGAAASKEYSL 1004
Query: 1022 EAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLK 1081
E L +++ W F + +RD+ D IL DDIQ+LLDD I T+ S ++ P++
Sbjct: 1005 EKNLDRMKLDWVNVTFSFVKYRDT-DTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIE 1063
Query: 1082 TRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEI 1141
+W+++L L+ WL CQ WLYLE IF++ DI Q+P E + F VD WK +
Sbjct: 1064 AECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSL 1123
Query: 1142 MRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELL 1201
M + + L AA QP + E Q N LL+ IQK L YLE KR+ FPRF+FLSNDELL
Sbjct: 1124 MSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELL 1183
Query: 1202 EILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPE 1261
EIL++T++P VQPHL+KCF+ I+KLEF +I+ M+S E
Sbjct: 1184 EILSETKDPLRVQPHLKKCFEGIAKLEFT-------------------DNLEIVGMISSE 1224
Query: 1262 GERVSLGKGL---KARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPS 1318
E V + + A+G VE+WL +VE+ M S+R + I Y R WV+ P
Sbjct: 1225 KETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQW-PG 1283
Query: 1319 QVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNIL 1378
QV++ VS I W +++++ L L +F K + +++ + +V+G L R L
Sbjct: 1284 QVVICVSSIFWTQEVSQALAEN------TLLDFLKKSNDQIAQIVQLVRGKLSSGARLTL 1337
Query: 1379 TALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEY 1438
AL IDVHARD+V +L + +V + F W QLRYYW + ++ ++ YGYEY
Sbjct: 1338 GALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAK--DVQVQIITTEALYGYEY 1395
Query: 1439 LGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNC 1498
LG PRLVITPLTDRCY LMGAL+L+LGGAP GPAGTGKTETTKDLAKALA QCVVFNC
Sbjct: 1396 LGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNC 1455
Query: 1499 SDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFE 1558
SDGLDYK MG+FF GLAQ+GAW CFDEFNRI++EVLSV+AQQ+++I+ A KL F+FE
Sbjct: 1456 SDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFE 1515
Query: 1559 GREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESS 1618
G E+ L TCA FITMNPGYAGR ELPDNLKALFR AMMVP+YALI E+ LYS GF S
Sbjct: 1516 GTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDS 1575
Query: 1619 KILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQD 1678
+ LA+K+ Y+LCSEQLS Q HYD+GMRAVKSVL AG+LK + P+ NE V+L+RAL D
Sbjct: 1576 RSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLD 1635
Query: 1679 SNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQ 1738
NL KFL D LF GIISDLFPGV +P+ DY + + D + + LQP + K+IQ
Sbjct: 1636 VNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQ 1695
Query: 1739 FYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITM 1798
YE MLVRHG M+VG GGKT+ Y++LA LG+L F AV+ ++NPK+ITM
Sbjct: 1696 IYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEF--AVEYKIINPKAITM 1753
Query: 1799 GELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKM 1858
G+LYG + ++ EW DG++A + R + S+D KWII DGPVDA+WIENMNTVLDDNK
Sbjct: 1754 GQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKK 1813
Query: 1859 LCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISK 1918
LCL + E I++ ++ ++FE DL ASPATVSRCGM++++P +L W P ++M +
Sbjct: 1814 LCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPS 1873
Query: 1919 KLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLI-----LGK 1973
LT+E +E + ++F V L F C + I ++ L SL+ + +
Sbjct: 1874 SLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEE 1933
Query: 1974 DGVNLA--MEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQF----DDNPDA 2027
+ + L + ++ L F+F +W++ G + + FD F R D++P
Sbjct: 1934 EEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRP 1993
Query: 2028 R---------LPNSGDLWSIHMDFDTK-RLDPWERIIPTFKYNRDVP----FFEMLVPTT 2073
+ P G ++ + + W + I K VP E+++PT
Sbjct: 1994 KSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYIT--KEEEKVPAGAKVSELIIPTM 2051
Query: 2074 DTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSA 2133
+T R + ++ L + +LF G TG GKS I L + ++ Y+P +NFSA+TS+
Sbjct: 2052 ETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNT-YLPNCINFSARTSAN 2110
Query: 2134 RTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFY 2193
+TQ+II SKL+R+RK + G P K+ V+FVDDLNMP + YG+QPPIELLRQ+ D G ++
Sbjct: 2111 QTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWF 2170
Query: 2194 DRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNG 2253
D+ +I D+ +++A PPGGGRN +T RF RH +++ + + L +IF +I++
Sbjct: 2171 DKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDW 2230
Query: 2254 -FLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDP 2312
F F + +V+A+ IY + LPTP+KSHYVFNLRD S+ +QG+L C
Sbjct: 2231 HFGKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPH 2290
Query: 2313 GTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKP- 2371
+++ + RL+ HE RVF+DRLI+ ED+ F ++ E + F I+ P
Sbjct: 2291 THLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPT 2350
Query: 2372 ----------IIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVF 2421
+ FGD+ K +D+ +IYD++ D+++ V++ YL+++N + + LV
Sbjct: 2351 GKIVDDNIRSLFFGDYFKPESDQ--KIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVM 2408
Query: 2422 FQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDS 2481
F+ AIEH+SRI R+++Q++G+ LLVG+GG+G+QS +L+ + Y+ QIE+++ Y +
Sbjct: 2409 FRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGND 2468
Query: 2482 FHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDE----LE 2537
+ EDL+K+ GV K+ VFLF D QI E F+EDIN +LN+G+VPN+F DE +E
Sbjct: 2469 WREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVE 2528
Query: 2538 QVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVN 2597
++ A R + ++V ++ + ++ +FI +V K+ L MSP+G+AFR+R RMFPSL+N
Sbjct: 2529 KMQTAARTQGEKVEVTPLS---MYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLIN 2585
Query: 2598 CCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELR 2657
CCTIDWF WP +AL V+ F V+ ++ ++ ++ MC SV ++ YYN+LR
Sbjct: 2586 CCTIDWFQSWPTDALELVANKFLEDVEL-DDNIRVEVVSMCKYFQESVKKLSLDYYNKLR 2644
Query: 2658 RRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALE 2717
R Y TPTSYLELI + ++L+ KR+++ R+R GL KL V M+ +L+AL+
Sbjct: 2645 RHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQ 2704
Query: 2718 PVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEAL 2777
P L+ SE+ +M K+ + AD + VQ DE A V A Q I ++ + DL EA+
Sbjct: 2705 PQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAM 2764
Query: 2778 PALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPD------------- 2824
PAL+AA ALD+L+ ADIS ++ PP V VME+I I+ KP+
Sbjct: 2765 PALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIE 2824
Query: 2825 --WPSAKQLLGDSNFLKRLLEYDKENIKPQILAKL-QKYINNPDFVPEKVEKVSKACKSM 2881
W +K++LGD FL+ L YDK+NI P + ++ +++IN+P+F P ++ VS AC+ +
Sbjct: 2825 DYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGL 2884
Query: 2882 CMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYD 2941
C WVRAM++Y RV KVV PKR++LR A+ +L M L +K+A L+ V D++QAL D+++
Sbjct: 2885 CKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFE 2944
Query: 2942 KGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAA 3001
+ +K+ L + + + +LVRA KL + L E+ RW E+ ++ +N+TG+V +++
Sbjct: 2945 EMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSG 3004
Query: 3002 CVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLI 3061
VAY GAFT YR W+ +C+ IP FSL + LGDP +IR W GLP D
Sbjct: 3005 TVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSF 3064
Query: 3062 STENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLP 3121
S +NGI+V+ RRW LMIDP QAN+WI+N E + L +IK +DSN++R+LEN+++LG P
Sbjct: 3065 SIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTP 3124
Query: 3122 VLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPE 3181
VL+E + E LD ++EPILLK F G +RLG++ I+Y ++F+ Y+TT++ NPHYLPE
Sbjct: 3125 VLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPE 3184
Query: 3182 VCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILR 3241
V +KV ++NF +T GL+DQLL V EKP LEE++ +LIV +K LK IE+KIL
Sbjct: 3185 VAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILE 3244
Query: 3242 MLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVM 3301
+L S+GNIL++E I L SK+ S I + + A TE I+ R Y+PVA + +
Sbjct: 3245 VLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATI 3304
Query: 3302 YFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRG 3361
+F I+ L+ I+PMYQYSL +F L+ ++ S K+E L R+ +++ L+ Y NV R
Sbjct: 3305 FFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRS 3364
Query: 3362 LFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFAC 3421
LFE+ KL++S +L + +M+Q+ +++ W F L G L+ P P WL W A
Sbjct: 3365 LFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPY-PNPAPQWLSEKAW-AE 3422
Query: 3422 CDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQ 3481
+ P HGL +++ + LG ++ + S HE++ K
Sbjct: 3423 IVRASALPKLHGLMEHLEQN-----LGEWKLIYD-------SAWPHEEQLPGSWK----- 3465
Query: 3482 DPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTP 3541
+S GL K+++++C + +K+V A+ +F+ E++GK +IE P DL Y D SC P
Sbjct: 3466 --FSQGL---EKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAP 3520
Query: 3542 LVFILSTGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN 3600
L+F+LS +DPM +FA + G R Q+ISLGQGQGPIA KM+ +A+K G WV LQN
Sbjct: 3521 LIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQN 3580
Query: 3601 CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL 3660
CHLA SWM +E++ + P+S FRL+L+S PS FPV++LQN +K+TNEPPKGL
Sbjct: 3581 CHLAASWMPTLEKICEEVIVPEST-NARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGL 3639
Query: 3661 RANIRRAFTE---MTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFN 3717
RAN+ R++ P FF+ W++++FG+CFFHA++QER+ FGPLGWNI YEFN
Sbjct: 3640 RANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFN 3699
Query: 3718 DSDRECALLNLKLYCKEGK-IPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPET 3776
+SD ++ ++++ + K +P+DAL Y+TGE YGGRVTD D+R L ++L F+ E
Sbjct: 3700 ESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEI 3759
Query: 3777 LEEDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLIN 3836
E+ Y + Y+ P S Q + DY+ NLP+ PE+FG+HENA++ +ET+ L
Sbjct: 3760 EEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFE 3819
Query: 3837 TILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTT 3896
+L PR S GG GKS E+V+EL + +++P ++E + V + S+ T
Sbjct: 3820 GVLLTLPRQS-GGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEE----SMNT 3874
Query: 3897 VLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPS 3956
VL QE+ RFN L K++ SL L +AI G V+MS E+E+V+NS L +VPA+W+ +YPS
Sbjct: 3875 VLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPS 3934
Query: 3957 LKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDEL 4016
LKPLG +V DL+ R +F W+ +G P +WISGF+F Q FLTG QN+ARKY +PID +
Sbjct: 3935 LKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHI 3994
Query: 4017 SFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMV 4076
F++ V P Q V+E +PEDG + G+F++ +RWD K M
Sbjct: 3995 GFEFEVTP----QETVME-----------------NNPEDGAYIKGLFLEGARWDRKTMQ 4033
Query: 4077 IEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVL 4135
I ++LP + LP++ +P ++ +Y CP+YKT AR GTLSTTGHSTN+V+++
Sbjct: 4034 IGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIE 4093
Query: 4136 LPSKRSKDYWIAKGSALLCQL 4156
LP+ + +WI +G A LCQL
Sbjct: 4094 LPTDMPQKHWINRGVASLCQL 4114
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 2172 bits (5627), Expect = 0.0
Identities = 1276/3693 (34%), Positives = 2039/3693 (55%), Gaps = 167/3693 (4%)
Query: 510 IPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYIN 569
+P+F TE +LT ++ P+ + V +C + S + P
Sbjct: 891 VPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIEC--PPQKG 948
Query: 570 NKLEGKTCGTGPSLAAVFEDDKNFHTIISQ---IKETIQAAFESARIYAATFEKFQIFFK 626
+ E + + D II Q I + + + Y +++++ +K
Sbjct: 949 EEEE-------VVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWK 1001
Query: 627 ENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTRLLREKLIPS 686
++++ ++ ++P + E+L+ Y K + + ++ + + R L + +
Sbjct: 1002 LDKAIVMEKFAAKKPPCVAYDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQEN 1061
Query: 687 PLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEIQERIES 746
+ L +L +K+++ + E + L +P T + L + EI+ +
Sbjct: 1062 AKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLV 1121
Query: 747 LEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMKPSIVAVRNA---IDKSVGDRESSIKQ 803
+E V + Y+ M Y + P + + ++ + N ++ ++GD + + +
Sbjct: 1122 MELRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTE 1181
Query: 804 FCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKRAFQYK 863
++ ++ E + + D DK +L + LA +K +
Sbjct: 1182 LT---RGEIMNYRVQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELA 1238
Query: 864 SYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQV 923
+ +K F + ++ + L +V E+ +++++ + ++EW ++ + L+ ++L +
Sbjct: 1239 NAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGI 1298
Query: 924 SKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDAT 983
+ + + +L + + SV L+ K++ K+ +P+++DL+N L+ RHW + +
Sbjct: 1299 EGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVF 1358
Query: 984 LVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFVILPHR 1043
E TLE + + + + +I A E A+E +K++ D+W+ +F ++ +
Sbjct: 1359 FEMTET-FTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYC 1417
Query: 1044 DSKDV--FILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEW 1101
+ILG D+I LDD+T N+ +++ SR++GP V +W+K L+L + +E W
Sbjct: 1418 KGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIW 1477
Query: 1102 LTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLL 1161
+ QR W+YLESIF DI+ QLP EAK F +DK +K IM + + P R P L
Sbjct: 1478 MLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRL 1537
Query: 1162 ETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCF 1221
QN + L++ QK L YL+SKR FPRF+F+S+DELL IL + +P VQ H+ K +
Sbjct: 1538 SDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMY 1596
Query: 1222 DSISKLEFALMPPAEGKIPGIDGEP-EKVYTNDILAMLSPEGERVSLGKGLKARGNVEEW 1280
D+I+ L F DG+ EK+ + AM+S EGE + K L+A G VE+W
Sbjct: 1597 DNIASLRFN------------DGDSGEKL----VSAMISAEGEVMEFRKILRAEGRVEDW 1640
Query: 1281 LGKVEEAMFTSLRRLCKAAIADY-QGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECLET 1339
+ V M + R + K AI Y + + R DW++ + V+L SQ+ W ++ +
Sbjct: 1641 MTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLL-YQGMVVLAASQVWWTWEVEDVFHK 1699
Query: 1340 EHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSK 1399
QA+KN+ + +++ L + L K R ++ IDVHARDIV ++
Sbjct: 1700 AQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGS 1759
Query: 1400 VETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLM 1459
+ FDW+ QLR+YWD + D R + YGYEY+G RLVITPLTDR YL L
Sbjct: 1760 ILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLT 1819
Query: 1460 GALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGA 1519
AL + LGGAPAGPAGTGKTETTKDLAKAL + CVV NC +G+DY+ +G+ FSGLAQ GA
Sbjct: 1820 QALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGA 1879
Query: 1520 WCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPGYA 1579
W CFDEFNRID VLSVI+ Q+ TIRNA +L+ F FEG+EI L FITMNPGYA
Sbjct: 1880 WGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYA 1939
Query: 1580 GRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQ 1639
GRTELP+++KALFRP ++VP+ I E++L+SEGF +K LA+KMT +YKL EQLS+Q
Sbjct: 1940 GRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQ 1999
Query: 1640 DHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDL 1699
HYDFG+RA+KSVLVMAG LKR + DL EDVVL+RAL+D NLPKF+ +D LF G+ISDL
Sbjct: 2000 YHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDL 2059
Query: 1700 FPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGK 1759
FPG+ P Y + V+ V KV+Q +ETML RH M+VGPT GGK
Sbjct: 2060 FPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGK 2119
Query: 1760 TTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMAL 1819
+ V L + KLG+ K Y+LNPK++++ ELYG ++ T +W DG+++
Sbjct: 2120 SVVINTLCQA---QTKLGL------TTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSN 2170
Query: 1820 SVRAAVNDT-SEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFE 1878
R T ++ K+I+ DG VDALW+ENMN+V+DDN++L LAN ERI+L +LFE
Sbjct: 2171 IFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFE 2230
Query: 1879 VQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILN-LFQRYVD 1937
V DL+ ASPATVSRCGMV+VDP+ LK+ PY K W+ I K+ ++Y LN LF++YV
Sbjct: 2231 VGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKV----EQYNLNSLFEKYVP 2286
Query: 1938 EGLHFI---------NKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTI 1988
+ I +K +PQ D++ VT L +L++L+ G E L+ +
Sbjct: 2287 YLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEG--------EIEDLDLL 2338
Query: 1989 LCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFD----------DNPDARLPNSGDLWSI 2038
C F+ SLG +L E+ FD +I+ NP L+
Sbjct: 2339 ECY-FLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDF 2397
Query: 2039 HMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGIT 2098
H D + PW +++P + + + F +LV T DT R +++E+++ +K V+F G +
Sbjct: 2398 HFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGES 2457
Query: 2099 GVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKR 2158
G K+ + L + E V + +NFS++T+S Q +E+ +E++ K+ G P KR
Sbjct: 2458 GTSKTATTQNFLKNLSEETNIV-LMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKR 2516
Query: 2159 IVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK-LFWKEIQDVTIISACAPPGG 2217
+++F+DD+NMPR+D YG+Q PI LL+ + G YDR K L K I+D+ I+A GG
Sbjct: 2517 LLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGG 2576
Query: 2218 GRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIY 2277
GRN V PRFI FS+ +P PSE SL I+ +IL G S F ++ + + ++ +Y
Sbjct: 2577 GRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLALY 2636
Query: 2278 NKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRL 2337
+ DL PTP+K HY+FNLRDLS+ G++ +P + Q+ R++ +EC RVFHDRL
Sbjct: 2637 KNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRL 2696
Query: 2338 INNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEK 2397
I+ DK + + +HF D+E + PI+FGDF + RIY+D+ D E
Sbjct: 2697 ISETDKQLVQQHIGSLVVEHF--KDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEA 2754
Query: 2398 TANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLT 2457
+ Q+ L++YN +N K + LV F DA+EH++R+ R+IR +RG+ALLVGVGG+GKQSL+
Sbjct: 2755 AKALFQEILEEYNESNTK-MNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLS 2813
Query: 2458 RLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLED 2517
RLAA + +I LSRGY+ +SF EDL+ LY G+E+K M+FLFTD + E FLE
Sbjct: 2814 RLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLEL 2873
Query: 2518 INNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLC 2577
INN+L SG VP LF ++E E +L+ A + G+ ++ V+QYF++K LHIVL
Sbjct: 2874 INNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPA-KESVWQYFVNKSANNLHIVLG 2932
Query: 2578 MSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLM 2637
MSPVG+ R+ CR FP +VN IDWF+ WP +AL +V+K+F E E +
Sbjct: 2933 MSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKH 2992
Query: 2638 CVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLT 2697
V VH SV ++++ +LRR Y TP +YL+ IN Y +L EK + I+ R+ GL
Sbjct: 2993 VVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLD 3052
Query: 2698 KLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKV 2757
KL E I +D++ L+ + VL KS EAL+E++AV+ A++ + +E +
Sbjct: 3053 KLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEE 3112
Query: 2758 KAEETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISI 2817
+ + +A+ L E +P L+AA L LDK+D++EIR F KPP V TV E I I
Sbjct: 3113 QNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILI 3172
Query: 2818 LLNAKP-DWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSK 2876
+ K +W +AK ++ D NFL+ L+E D ++I + ++ + + E++E VSK
Sbjct: 3173 MKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSK 3232
Query: 2877 ACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQAL 2936
A M +V A+ Y V + ++PKR+K+ + +T L Q L ++ +++ L
Sbjct: 3233 AGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETL 3292
Query: 2937 QDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNV 2996
+Y+ + EK+ L + + + RL+ A KL + L E +RW + + + G+
Sbjct: 3293 GAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDC 3352
Query: 2997 FIAAACVAYYGAFTAQYRQSLI-ECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDG 3055
+ AA ++Y GAFT ++R ++ W D EIP+ F L ++L D EI +W + G
Sbjct: 3353 LLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQG 3412
Query: 3056 LPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENS 3115
LP D +S +NGIL T+ R+PL IDPQ QA WI+ KE K+ L++ D +FL+ LE S
Sbjct: 3413 LPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMS 3472
Query: 3116 IRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPN 3175
I+ G P L ++ E +DP ++ +L K I +S GR I LGD ++DYD NFR Y+ TK+ N
Sbjct: 3473 IKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLAN 3532
Query: 3176 PHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTI 3235
P Y P V K +IN+TVT GLEDQLLS +V E+ LEEQR LI + +KN LK +
Sbjct: 3533 PRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDL 3592
Query: 3236 EEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVA 3295
E+ +LR L TS GN+LDN +L+ TL+++K + + +L+ AE T I+ R+ YRP A
Sbjct: 3593 EDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAA 3652
Query: 3296 TQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAY 3355
+G++++FV++ ++ ++ MYQYSL F ++F +++ S+ L +RL +++ + Y
Sbjct: 3653 RRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIY 3712
Query: 3356 VNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPT 3415
+ GLFE+HKL++SF + +++ + +G + E +FFL+G+ LEK + KP A WL
Sbjct: 3713 NHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCA-WLSD 3771
Query: 3416 ATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQE 3475
W L E F G + + + N W+ + +
Sbjct: 3772 QGWEDIILLSEMFSDNFGQLPDDVEN-------------NQTVWQEW-----------YD 3807
Query: 3476 KEAAHQDPWSAG----LSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPT 3531
++ Q P G ++ F KL++++C + ++V A+TD+V +G+++++ P +
Sbjct: 3808 LDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEA 3867
Query: 3532 LYQDMSCNTPLVFILSTGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAM 3590
+++ + ++P+VFILS GSDP + A SG+ R++ +++GQGQ +A ++++ A+
Sbjct: 3868 IFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAV 3927
Query: 3591 KSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSV 3650
G W+ LQNCHL V W+ +E+ ++ T P FRL+L++ P+ FP+ +LQ S+
Sbjct: 3928 ARGQWLMLQNCHLLVKWLKDLEKSLERITKP----HPDFRLWLTTDPTKGFPIGILQKSL 3983
Query: 3651 KVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGW 3710
KV EPP GL+ N+R + +++ ++ ++ +++ + FFHA++QER+KFG +GW
Sbjct: 3984 KVVTEPPNGLKLNMRATYFKISHEMLDQ-CPHPAFKPLVYVLAFFHAVVQERRKFGKIGW 4042
Query: 3711 NICYEFNDSDRECALLNLKLYC------KEGKIPWDALIYITGEITYGGRVTDSWDQRCL 3764
N+ Y+FN+SD + + L Y ++ +IPW +L Y+ GE+ YGGR DS+D+R L
Sbjct: 4043 NVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRIL 4102
Query: 3765 RTILKRF---FSPETLEEDYKYSESGI-YFAPMADSLQEFKDYIENLPLIDDPEIFGMHE 3820
+ + F +T + + + + Y P+ D ++F + IE LPL + PE+FG+H
Sbjct: 4103 TIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHP 4162
Query: 3821 NANLVFQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASE 3880
NA + + + + +LE+QP++ G S D+ + ++ ++ ++P+ +++
Sbjct: 4163 NAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVR- 4221
Query: 3881 SLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSF 3940
K L L+ + VL QE++RFN L+ + SL L +A+AG V MS E++ V S
Sbjct: 4222 ----KRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSL 4277
Query: 3941 LNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTG 4000
+P +W A +LK LG+W+ + R S LW+ +P W+SG P+ +LT
Sbjct: 4278 FIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTA 4337
Query: 4001 TLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLV 4060
+Q RK P+D S ++ + ++D V E A GQ G V
Sbjct: 4338 LVQATCRKNGWPLDR-STLFTQVTKFQDADEVNERA-----GQ-------------GCFV 4378
Query: 4061 HGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAG 4119
G++++ + WD ++ + + P + LP++ P + ++ + P+Y T R
Sbjct: 4379 SGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRN 4438
Query: 4120 TLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSAL 4152
+ V L + R +W+ +G L
Sbjct: 4439 AM-----GVGLVFEADLFTTRHISHWVLQGVCL 4466
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 2159 bits (5594), Expect = 0.0
Identities = 1369/4074 (33%), Positives = 2105/4074 (51%), Gaps = 592/4074 (14%)
Query: 511 PMFLTELMLTVQSLLFEPSLEDFLDGILGAVNH----CQNTVLSVPNLVPDSYFDAFTSP 566
P F T L + L F +++ L + + CQ+ LS+ + D +
Sbjct: 607 PEFPTNLFIDPNRLEFSVKIQNMLTNMEKCITTITPLCQDPQLSI-------FIDLVSIM 659
Query: 567 YINNK----LEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATFEKFQ 622
+ NK + K P +FE D + II + I + Y+ F K+
Sbjct: 660 DLPNKTGSIIHYKEQTRWPDCHILFETDPAYQNIIVNLLTIIGNSMGLVNAYSHKFIKYC 719
Query: 623 IFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTRLLREK 682
++ + + ++ + E F L ++ + V + + +G+ + + + +
Sbjct: 720 TMTEKAKIMSMKISSMGELTSKEFEAILNRFRNYFRHIVNMAIEKRIGIFNVVSLDYQSE 779
Query: 683 LIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEIQE 742
+ + + + ++ +KK ++ + + +LE PT E++ +FL+ I
Sbjct: 780 CLLYIDNVIHMSHTLIQSVIEKKNKNLLEVVESSLQQLECDPTEIEEFLEHFIFLNAISS 839
Query: 743 RIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKSVGDRESSIK 802
+I LE E ++Q+Y + + +Q+ E A+F + +++++ S +++++I
Sbjct: 840 KISKLEKEFLTMSQLYSVAKHHQIHISEEQIAIFQVLLLKFSQLKSSMKLSKINKDTAIT 899
Query: 803 QFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKRAFQY 862
+F +L + + L+ +V +K + + P +L ++ L A L +A Y
Sbjct: 900 KFRDNLEACISGLHVDVGNLKAKIRTPLLLCAGTQVSTAMEMIQTLSGEAASLTNKAKAY 959
Query: 863 KSYQKNFKVEVSKFEA-------------LEEVSAELKLKQLLWDSFSEWDKLQQEWLKS 909
YQ F S + + ++ +L L++ LW++ EW + EW S
Sbjct: 960 SHYQDCFSDSQSHMHSVNVEEITQIVLSEISDIEGDLTLRKKLWEAQEEWKRASWEWRNS 1019
Query: 910 KFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLK 969
+D E + VSK ++ LEKGLP + +V LK V + K++LP+II L NP LK
Sbjct: 1020 SLQSIDVESVQRNVSKLMHIISVLEKGLPKSDMVTHLKQVVTEFKQELPIIIALGNPCLK 1079
Query: 970 ARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVE 1029
RHW A+++ + + V + +E L L +F + EI D+S A+ EAALE +L K+
Sbjct: 1080 PRHWEALQEIIGKS-VPLDKNCKVENLLALKMFQYENEINDMSTSATNEAALEKMLFKII 1138
Query: 1030 DSWKTTEF-VILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQ 1088
D W TT +IL H + +FI+ DDI L++S + +AT+ S ++GP+K V+EW
Sbjct: 1139 DFWNTTPLPLILHHTEIYSIFIIPSIDDISAQLEESQVILATIKGSPHIGPIKDLVNEWD 1198
Query: 1089 KQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRL 1148
+ L LF+ TLEEW+ CQRNWLYLE +F++ +I+RQLPAE ++F QV WK+IM K+
Sbjct: 1199 QNLTLFSYTLEEWMNCQRNWLYLEPVFHSSEIRRQLPAETELFSQVISMWKKIMSKIQNK 1258
Query: 1149 PNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTR 1208
NAL+ T G+LE QN N L+ I+K LE YLE KR+IFPRFYFLSN ELL+ILA +R
Sbjct: 1259 QNALQITTSAGVLEILQNCNIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAELLDILADSR 1318
Query: 1209 NPQAVQPHLRKCFDSISKL---EFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERV 1265
NP++VQPHL KCF++I +L + + PPA + ++S EGE +
Sbjct: 1319 NPESVQPHLVKCFENIKQLLIWKQDIGPPA------------------VKMLISAEGEGL 1360
Query: 1266 SLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVS 1325
L K ++ R VE+WL VE++MF L+ K R + + ++L S
Sbjct: 1361 VLPKKIRVRSAVEQWLVNVEKSMFDVLK------------KERYIYNI------ILLFQS 1402
Query: 1326 QIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAI----VQGSLPKLHRNILTAL 1381
QIM+ D + + +S + EKV+ + L + V + + IL AL
Sbjct: 1403 QIMFYNDCVKSFVSSYSR-----EKLEKVHAGLMCHLEEVADLVVLDTSNSRTKAILGAL 1457
Query: 1382 ITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGA 1441
+ + VH RDIV L+ + E F+W R L+Y W+ C + +TYGYEYLG
Sbjct: 1458 LILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNASFTYGYEYLGC 1517
Query: 1442 CPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDG 1501
RLVITPLTDRC+L LM AL L+LGG PAGPAGTGKTET KDLAK+L CVVFNC +
Sbjct: 1518 TSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGKHCVVFNCFED 1577
Query: 1502 LDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGRE 1561
LDYK++ +FF GL QSGAW CFDEFN ID+EVLSVIA Q++TI+ AK +RF+ EG+E
Sbjct: 1578 LDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKDNYSARFVLEGKE 1637
Query: 1562 IKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKIL 1621
I++ M+CA FITMNP Y G ELPDNLK+LFRP AMMVP+Y +IAE+IL+S GF+S+ L
Sbjct: 1638 IRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSFGFKSANSL 1697
Query: 1622 ARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRE---NPDLNEDVVLIRALQD 1678
+ K+T +Y+L +QLSQQDHY+FG+R++K VL+MAG+ KRE + +E +++I A+++
Sbjct: 1698 SGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLSEADETLIVIEAIRE 1757
Query: 1679 SNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQ 1738
++LPK +D LF II D+FP V + + + L+ I + LQ K+IQ
Sbjct: 1758 ASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQNWSSQKEKIIQ 1817
Query: 1739 FYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNL----------QKLGIENSFYQA-VK 1787
FY + V GVMLVGPTGGGKTTV RIL + L L +K + S + V
Sbjct: 1818 FYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSASKISERKGKVD 1877
Query: 1788 TYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAV---------------------- 1825
VLNPK +T+ ELYG+++ T+EW DGL++ ++R+ V
Sbjct: 1878 ICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDIDLRLKSRISD 1937
Query: 1826 ---------NDTSE---------------------DHKWIISDGPVDALWIENMNTVLDD 1855
+DT+E D +WII DGPVD W+EN+N+VLDD
Sbjct: 1938 LSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFWVENLNSVLDD 1997
Query: 1856 NKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKG 1915
+ LCLANSERI LT +I ++FEV +L ASPATVSRC MV++DP +L W PYVK+W+
Sbjct: 1998 TRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGWEPYVKSWLLK 2057
Query: 1916 ISKKLTEETQEYILNLFQRYVDEGLHFI-NKKCSQAIPQVDISKVTTLCCLLESL--ILG 1972
SK +++ + + + + V +GL FI N++ Q P DI+ V TLC +L++ +G
Sbjct: 2058 TSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVITLCRILDAFFDFMG 2117
Query: 1973 KDG---------------VNLAMEQT--------------------KLNTILCQTFVFCY 1997
K+G N E KL I+ + FVF +
Sbjct: 2118 KNGGFEQSDDLNDTSSKEANSQRESVTFKDIEKRDENTWYPEKNPDKLTKIIQKLFVFAF 2177
Query: 1998 LWSLGG---------------------NLTENYYDSFDTFIRTQFDDNPDARLPNSG--- 2033
W+ GG +L + YD FD + F ++ + G
Sbjct: 2178 TWAFGGALNREDEHRENIPFCPSLEPDSLAKVTYD-FDKLVHELFGNSSQVGWKHWGQSQ 2236
Query: 2034 ----------------DLWSIHMDFDTKRLDPWERIIPTFK--YNRDVPFFEML------ 2069
++ +D + PW ++P + R L
Sbjct: 2237 GRRRKGNCINLPTGECSIFGYFVDIEQCEFIPWSDLVPNDQTLIQRGTSLLTNLQRSGGN 2296
Query: 2070 -------------VPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQES 2116
T DT +LM LL VL TG +GVGK+ +L K++
Sbjct: 2297 FLKITECGECINYTATRDTTCLSFLMSLLLKNSCPVLLTGESGVGKTAAINQMLEKLEGP 2356
Query: 2117 AGY--------------------------VPVYLNFSAQTSSARTQEIIESKLERKRKNI 2150
+ + + + + +T++ + + R K +
Sbjct: 2357 GAFDIKHGSILGDTLLYSEIKKSSSLKQNITILIPETHKTATGSSDNPTKKPEVRTNKKL 2416
Query: 2151 LGAPGNKRIVIFV-------------------------DDLNMPRLDR------------ 2173
L +K +V+ D L P+ +R
Sbjct: 2417 LKNNDHKGVVVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPV 2476
Query: 2174 ---YGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHF 2230
YG+QPP+EL+RQ D GG YD K WK IQD++I++AC P N ++PR ++HF
Sbjct: 2477 SDMYGAQPPLELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPV---VNDISPRLLKHF 2533
Query: 2231 SMLCLPMPSEHSLKQIFQAILNGFLS--DFPPAVKQTASSIVEASVEIYNKMSVDLLPTP 2288
SML LP PS+ L IFQA L + S +F P V+++ I+ S+ IY+++ ++LPTP
Sbjct: 2534 SMLVLPHPSQDILCTIFQAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTP 2593
Query: 2289 AKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHV 2348
K HY+FNLRD+ K + G+LQ D + + LF HE RVFHDRLI+ DK F+
Sbjct: 2594 TKCHYMFNLRDMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYR 2653
Query: 2349 ILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDD 2408
+L+ F I ID G K KT L YL D
Sbjct: 2654 LLSRELENCFQIGID-----------------GCGK------------KTCATLACYLTD 2684
Query: 2409 YNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKC 2468
L ++ I H + A + +E + + G GK ++ +
Sbjct: 2685 NKL----------YRVPISH--KCAYIEFKEVFKKVFIHAGLKGKPTVLMVPN------- 2725
Query: 2469 LQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVP 2528
L IE DSF EDL + + D
Sbjct: 2726 LNIE------QDSFLEDLNYIISSGRIPD------------------------------- 2748
Query: 2529 NLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSR 2588
LFE EL+ + R ++ G + NR + +F ++ + LHI + MSP G +FR
Sbjct: 2749 -LFENVELDSIAMKIRYLTEQSGHMD-NRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQN 2806
Query: 2589 CRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQ-VDAGN-EELKEKLPLMCVNVHLSVS 2646
CR++PS+++ CTIDW+ +WP EALL V+ +F + V+ N E LKEKL CV +H S+
Sbjct: 2807 CRVYPSMISSCTIDWYERWPEEALLIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMK 2866
Query: 2647 SMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILV 2706
+ +Y+ E R YYTTP SYL+ + + +L + +++ + RDR GL+ +LE LV
Sbjct: 2867 DLNRKYFEETGRFYYTTPNSYLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLV 2926
Query: 2707 DKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIA 2766
+M+ +L L P + K+++ E LMEKL D + ++V+ V++DE ++ AEE + +
Sbjct: 2927 TEMQEELLILGPQVEQKTKETETLMEKLRKDSQVVEKVQMLVKQDE---EIVAEEVRIVE 2983
Query: 2767 DDAQR---DLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKP 2823
D AQ+ +L LPA D A AL++LDKAD++E+RV+T+PP LV+TVM A+ ILL KP
Sbjct: 2984 DYAQKTANELKSVLPAFDKAIVALNALDKADVAELRVYTRPPFLVLTVMNAVCILLQKKP 3043
Query: 2824 DWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCM 2883
+W +AK LL ++ FLK+L+ DK++I ++ KL+K + PDF P K+ VS AC S+C
Sbjct: 3044 NWATAKLLLSETGFLKKLINLDKDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQ 3103
Query: 2884 WVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKG 2943
WV A++ Y V KVV PK+ ++ AQ L I L EKQ L+ VE+ + LQ Y
Sbjct: 3104 WVIALNNYHEVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDT 3163
Query: 2944 VNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACV 3003
V EK+ LA + R A L LEDE+ RW+E+I + + ++ I G++ ++AAC+
Sbjct: 3164 VAEKQLLANRKTMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACI 3223
Query: 3004 AYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLIST 3063
Y G T ++RQ ++ W C I + FSLI ++ YEI +W+ GLP S
Sbjct: 3224 VYSGILTPEFRQLIVNKWETFCIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSV 3283
Query: 3064 ENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVL 3123
EN IL+ G++WPL+IDP QA++WIR E S L+ + + DSN+ + +EN+++ G VL
Sbjct: 3284 ENAILIKNGQQWPLLIDPHRQAHKWIRQMEG-SRLQKLSIEDSNYTKKIENAMKTGGSVL 3342
Query: 3124 LEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVC 3183
L+ L ETL P L+ IL K I+ G IR+GD++ +Y+ NFR Y++T++ NPH+LP V
Sbjct: 3343 LQNLLETLAPGLKAILKKDIYQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVY 3402
Query: 3184 IKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRML 3243
VT+INFTVT GL+DQLLS VV E P LE+QR KL+ I+ D L+ +EEK L +L
Sbjct: 3403 NFVTMINFTVTFQGLQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLL 3462
Query: 3244 FTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYF 3303
+ G+ILD+++++DTL+ SK+TS I R+E + E I R+ Y P+AT+G+++YF
Sbjct: 3463 QKALGSILDDDKIVDTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYF 3522
Query: 3304 VIASLSEIDPMYQYSLKYFKQLFNTTI-------ETSVKTE-----------------NL 3339
++A L++I+ MYQ+SL +F Q+F +++ E S K E NL
Sbjct: 3523 LVADLTQINYMYQFSLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNL 3582
Query: 3340 QQRLDVL-------LEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQ---------- 3382
+ ++L ++ + + VS LF + KL +SF LC +M+
Sbjct: 3583 ENEKNLLDKHIKSAIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDI 3642
Query: 3383 GTLSDAEWNFFLRG------SAGLEKER-------PPKPEAPWLPTATWFACCDLEESFP 3429
G L + EWN FL + L + R WL + W C +
Sbjct: 3643 GFLPEEEWNIFLYSGILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLE 3702
Query: 3430 VFHGLTQNILSHPISIRLGSFETYINPQ---------------KWEGYSKMKHEDKHMRQ 3474
F L +++LS+ + ++T+ N + E +K E + + +
Sbjct: 3703 PFSLLCKSLLSN-----VSQWDTFKNSKAVYSLISTPFSSENASLEENTKPPEETELLNE 3757
Query: 3475 EKEAAH--QDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTL 3532
KE + PW L+SF +LIL+K + E + ++ F+ E +G ++++ V+L
Sbjct: 3758 NKETCNPINFPWEK-LTSFQRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDA 3816
Query: 3533 YQDMSCNTPLVFILSTGSDPMGAFQRFARE-SGYSERVQSISLGQGQGPIAEKMVKDAM- 3590
Y+ + TPL+ I + G D RFA+E G + V ISLG+ Q AE ++ A+
Sbjct: 3817 YKGSNARTPLILIQTHGIDLTNILLRFAQELKGTTHHVTIISLGRDQAAKAEDLILKALT 3876
Query: 3591 KSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSV 3650
K+ WVFLQNCHLA S+M + ++++F P+ I FRL+LSS ++FP+ VL+ +
Sbjct: 3877 KTQQWVFLQNCHLATSFMPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSSFPIPVLKKGL 3936
Query: 3651 KVTNEPPKGLRANIRRAF-----TEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKF 3705
K+ E P+GL++N+ + F E+T FE G+ W++++F +CFF+A+I ERK +
Sbjct: 3937 KIAVESPQGLKSNLLQTFGCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNY 3996
Query: 3706 GPLGWNICYEFNDSDRECALLNLKLYCK-EGKIPWDALIYITGEITYGGRVTDSWDQRCL 3764
G LGWNI Y+FN SD A+ L+ + + I W AL Y+ GE+ YGGRV D+WD+RCL
Sbjct: 3997 GILGWNIAYKFNSSDLGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCL 4056
Query: 3765 RTILKRFFSPETLEEDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANL 3824
+T+L +F +PE L++D+ +S S S++++ I++LP D PE+ G+H A
Sbjct: 4057 KTLLYKFCNPEVLKDDFSFSRSA--------SIKDYIHIIQSLPDDDLPEVLGIHPEAIR 4108
Query: 3825 VFQYKETSTLINTILEVQPRSSTGG----EGKSNDEIVQELVASVQTRVPEKLEME---- 3876
+ I ++ +QP+++T +S DE+V E+++ + R+P +E E
Sbjct: 4109 SCWETQGEKFIENLIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAV 4168
Query: 3877 ---GASESLFVKDLQGRLNS------------LTTVLGQEVDRFNNLLKLIHTSLETLNK 3921
+S+ + L+ L T L QE+ RF+ LL +IH SL+ L
Sbjct: 4169 GTPSTLKSMMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQL 4228
Query: 3922 AIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLK-- 3979
AI G +++++E+E+++NSFLN +VP LW AY S KPL SW+ DLI R +F + W K
Sbjct: 4229 AIKGEIILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVA 4288
Query: 3980 -------------------------------------RGQPKSYWISGFFFPQGFLTGTL 4002
G P YW+ FFFPQ FL L
Sbjct: 4289 YTAIQRRYMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVL 4348
Query: 4003 QNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMEL--------PSP 4054
Q++ R + +D L+F + VI D K +F +P + + S
Sbjct: 4349 QDYGRSRGIAVDALTFTHHVISNTTD--------KDEKFSVFMPKKLNIVRRAFKGSASS 4400
Query: 4055 EDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYKPSPT--------- 4105
GV + G+F++ +RW+ ++ ++ED+LP +M P ++F P + +P
Sbjct: 4401 HTGVYIFGLFIEGARWNREQKILEDSLPLEMCCDFPDIYFLPTKISTKTPNASNQTDSEL 4460
Query: 4106 -LYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQLSE 4158
+ CP+Y+T R+ L+TTG TNF+ +V L +K+ +WI ALLC+ +E
Sbjct: 4461 YAFECPVYQTPERSRILATTGLPTNFLTSVYLSTKKPPSHWITMRVALLCEKNE 4514
Score = 65.5 bits (158), Expect = 1e-09
Identities = 49/186 (26%), Positives = 88/186 (47%), Gaps = 20/186 (10%)
Query: 201 FLYMIPAVPRSSIEYDTYNLKVVSYENINK-NDYYTISQRAVTHIYN-----EDIEFIEI 254
F+Y +P S+ Y+ Y+L+VVS +++ I+ ++ + N +++E I
Sbjct: 175 FVYCLPRKSPKSL-YNPYDLQVVSAHTAKHCKEFWVITASFISKVINIVGSVKEVELIPT 233
Query: 255 DRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKSLQKNLFIVNPHLRP 314
W E ++ L + IFS FR KAF W+ NV+ K + L +LF+ + +
Sbjct: 234 LEWLSERRHYYLLRQFKIFSDFRMNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQT 293
Query: 315 ALLKINELC-------------YHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERLG 361
L+ I LC +LS + L ++ TY+L EF Q+ + + ++L
Sbjct: 294 CLVYIRGLCEDAINLKNYNDHENNLSAICLVKLDSSRTYSLDEFCEEQLQQATQALKQLE 353
Query: 362 EFRNEA 367
+ RN+A
Sbjct: 354 DIRNKA 359
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 2048 bits (5307), Expect = 0.0
Identities = 1237/3728 (33%), Positives = 1971/3728 (52%), Gaps = 217/3728 (5%)
Query: 499 MVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDG-ILGAVNHCQNTVLSVPNLVPD 557
++E E L P+F +L L + L+F PSLE + G V ++ +P+LVP
Sbjct: 906 LLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVP- 964
Query: 558 SYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAAT 617
SP+ L+G P LA + + E +Q Y +T
Sbjct: 965 RLSPQNGSPHYQVDLDGI-----PDLA----------NMRRTLMERVQRMMGLCCGYQST 1009
Query: 618 FEKFQIFFKENESLDLQALKL--------------------QEPDINFFSEQLEKYHKQH 657
F ++ + E+ L L P ++ F Q++ Y +
Sbjct: 1010 FSQYSYLYVEDRKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLY 1069
Query: 658 KDAVALRPTRNV-GLLLIDTRLLREKLIPSPLRCLEVLNFMLP---RQSKKKVDAIIFEA 713
++ L P + G + ID R + L+ R + L S +DA I ++
Sbjct: 1070 EEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKS 1129
Query: 714 QDAEYKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDF 773
+ K + V + L ++ER + ++ + Q +L++ Y+ P F
Sbjct: 1130 ESGLLK-KVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVF 1188
Query: 774 AVFATM-------KPSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNE---VK 823
+ K + V+ + + + ++Q C ++ ++ + ++ +
Sbjct: 1189 KQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFR 1248
Query: 824 LQAQDP-QILDISADQDKIRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEV 882
+ P Q+LD + + ++S +A + + A F+V V ++ L +
Sbjct: 1249 FDSIHPHQMLDAR------HIEIQQMESTMASISESA-------SLFEVNVPDYKQLRQC 1295
Query: 883 SAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSV 942
E+ + LWD+ W + + ++ E + + ++A+ + L+K +
Sbjct: 1296 RKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDA 1355
Query: 943 VPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVF 1002
L+ V L + +L+NP ++ RHW + Q + + TL L QL +
Sbjct: 1356 FTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFT-MDQDTTLAHLLQLQLH 1414
Query: 1003 DFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLD 1062
+ E++ I +A+ E +E LK+++ +W EF PH + +V +L +D+ +L+
Sbjct: 1415 HYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRT-NVPLLCSDEDLIEVLE 1473
Query: 1063 DSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFN-APDIQ 1121
D+ + + L S+Y+ V WQK+L+ + + W QR W +LESIF + DI+
Sbjct: 1474 DNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIR 1533
Query: 1122 RQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAY 1181
QLP ++K F +D +KE+ ++PN ++ +PGL E ++ L +K L Y
Sbjct: 1534 AQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEY 1593
Query: 1182 LESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPG 1241
L++KR+ FPRFYFLS+ +LL+IL+ PQ VQ HL K FD+++K+ F L
Sbjct: 1594 LDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQL---------D 1644
Query: 1242 IDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIA 1301
GEP K L M S E E V+ + G VE WL V M ++R +
Sbjct: 1645 ASGEPTKTS----LGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVT 1700
Query: 1302 DYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNA 1361
Y+ K R W+ HP+QV LT +QI W ++ + A+K++ K +L
Sbjct: 1701 AYEEKPREQWLF-DHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKT 1759
Query: 1362 LAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLD 1421
L ++ G L K R + + TIDVHARD+V +++ KV+ ++F W QLR+ WD ++
Sbjct: 1760 LITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVK 1819
Query: 1422 NCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTET 1481
+C A + +Q+ Y YEYLG PRLVITPLTDRCY+ L +L L + GAPAGPAGTGKTET
Sbjct: 1820 HCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTET 1879
Query: 1482 TKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQL 1541
TKDL +AL I VFNCS+ +DYK G + GLAQ+GAW CFDEFNRI +EVLSV+A Q+
Sbjct: 1880 TKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQV 1939
Query: 1542 ITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPN 1601
+I++A K F F G EI L + FITMNPGYAGRTELP+NLK+LFRP AM+VP+
Sbjct: 1940 KSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPD 1999
Query: 1602 YALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKR 1661
+ LI E++L +EGF ++ LARK +Y+LC E LS+QDHYD+G+RA+KSVLV+AGSLKR
Sbjct: 2000 FELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKR 2059
Query: 1662 ENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVM 1721
+PD ED VL+R+L+D N+PK +TDD +F G+I DLFP + +P ++ + +
Sbjct: 2060 GDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAI 2119
Query: 1722 NRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENS 1781
LQ E V KV+Q E + VRH V +VG G GK+ V R L +T +++ +
Sbjct: 2120 VDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTD 2179
Query: 1782 FYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPV 1841
LNPK++T EL+G +N T EWKDGL + +R N T + KWI+ DG +
Sbjct: 2180 ---------LNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDI 2230
Query: 1842 DALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPE 1901
D +WIE++NTV+DDNK+L LA++ERI L P + +LFE+ LR A+PATVSR G+++++P
Sbjct: 2231 DPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPA 2290
Query: 1902 ELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTT 1961
+L W P V +W I K+ + + + LF +Y+ L + + + IP + S V
Sbjct: 2291 DLGWNPPVSSW---IEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQM 2347
Query: 1962 LCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTE----NYYDSFDTFI 2017
+C LLE L+ +D + I FVF +W+ GG + + +Y F +
Sbjct: 2348 VCHLLECLLTTED-----IPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWW 2402
Query: 2018 RTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVR 2077
T+F + P+ G ++ ++D +TK+ +PW +++P F+++ ++P LV T++T+R
Sbjct: 2403 LTEF---KTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIR 2459
Query: 2078 YGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQE 2137
Y ME+L+A + V+ G G GKSV+ L + A Y+ + F+ T+SA Q
Sbjct: 2460 VCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEA-YLVKNVPFNYYTTSAMLQA 2518
Query: 2138 IIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK 2197
++E LE+K G PGNK+++ F+DD+NMP +D YG+ P ++RQ+ D+G +YDR+K
Sbjct: 2519 VLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSK 2578
Query: 2198 LFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGF--L 2255
L KEI +V +S C P G + PR RHFS+ L P +L I+ IL L
Sbjct: 2579 LSLKEITNVQYVS-CMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKL 2637
Query: 2256 SDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTI 2315
+FP +++++ +++ ++ + K++ LPT K HY+FNLRD + QGIL +
Sbjct: 2638 GNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECV 2697
Query: 2316 REEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFG 2375
+ + RL+ HE RV+ D+++ +D F I TE+ K F D P ++
Sbjct: 2698 KSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYC 2757
Query: 2376 DFIK-FGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIAR 2434
F G K Y + E L + L+++N N + LV F+DA+ HV I R
Sbjct: 2758 HFANGIGEPK----YMPVQSWELLTQTLVEALENHNEVN-TVMDLVLFEDAMRHVCHINR 2812
Query: 2435 MIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAG 2494
++ RGNALLVGVGG+GKQSLTRLAA I QI L +GY F DL L AG
Sbjct: 2813 ILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAG 2872
Query: 2495 VEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISE 2554
V++ N VFL TD Q+ E FL IN++L SGE+P+L+ DE+E +++ R K G+ +
Sbjct: 2873 VKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVD 2932
Query: 2555 GNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLS 2614
NR+ +++FI ++R++L + LC SPVG R R R FP++VNC I WF +WP++AL S
Sbjct: 2933 -NRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALES 2991
Query: 2615 VSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLY 2674
VS F + +K+ + VH SV+ ++ Y + +R YTTP S+LE I LY
Sbjct: 2992 VSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLY 3051
Query: 2675 LSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKL 2734
S+L RK++ +R++NGL KL T+ VD +K L+A E L K+ED + L++ +
Sbjct: 3052 QSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVV 3111
Query: 2735 AVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKALDSLDKAD 2794
V+ + + + E+E V E + D + DL +A PAL AA AL++L+K +
Sbjct: 3112 GVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTN 3171
Query: 2795 ISEIRVFTKPPDLVMTVMEAISILLNAK------PDWPSAKQLLGD-SNFLKRLLEYDKE 2847
++E++ F PP V V A+ +L+ + W +AK + FL L+ ++KE
Sbjct: 3172 LTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKE 3231
Query: 2848 NIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRA 2907
NI L ++ Y+ +P+F PE V S A +C WV + + V VEPKRQ L
Sbjct: 3232 NIHENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNK 3291
Query: 2908 AQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKL 2967
A A+L L +A + + + + L ++K +K + +T + A +L
Sbjct: 3292 ATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRL 3351
Query: 2968 TAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIE-CWIQDCQ 3026
L E VRW +++Q F+++ + G++ + A ++Y G FT +YRQSL++ W
Sbjct: 3352 VGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLS 3411
Query: 3027 SLE--IPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQ 3084
L+ IP+ P+ + +L D ++ W +GLP D +S EN ++ RWPLM+DPQ Q
Sbjct: 3412 QLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQ 3471
Query: 3085 ANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIF 3144
+WI+NK + L++ ++ +L+I+E ++ G VL+E L+E++DP L P+L +++
Sbjct: 3472 GIKWIKNKYGED-LRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREV- 3529
Query: 3145 ISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLS 3204
I GR I++GD + +Y+ FR + TK+ NPHY PE+ + T+INFTVT+ GLEDQLL+
Sbjct: 3530 IKKGR-FIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLA 3588
Query: 3205 DVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSK 3264
VV +E+P LE+ + L + N K LKT+E+ +L L ++ GN L L++ L+ +K
Sbjct: 3589 AVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITK 3648
Query: 3265 ITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQ 3324
T+ ++ +++EA+ TE IN ARE YRP A + S++YF++ LS+I PMYQ+SLK F
Sbjct: 3649 QTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSI 3708
Query: 3325 LFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGT 3384
+F +E + E+L++R+ L++ + Y RGLFE KL Y L +++
Sbjct: 3709 VFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNRE 3768
Query: 3385 LSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPVFHGLTQNILSHPIS 3444
++ E +F LR P +L W A L S F L ++I
Sbjct: 3769 VNAVELDFLLRSPVQTGTASP----VEFLSHQAWGAVKVL-SSMEEFSNLDRDIEG---- 3819
Query: 3445 IRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEK 3504
+ + W+ + + + EKE Q+ W ++ +L +++ + ++
Sbjct: 3820 ----------SAKSWKKFVESE------CPEKEKLPQE-WK-NKTALQRLCMLRAMRPDR 3861
Query: 3505 VVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESG 3564
+ +AL DFV E LG +++ +D T +++ TP+ FILS G DP+ + R+ G
Sbjct: 3862 MTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLG 3921
Query: 3565 Y---SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDP 3621
Y ++ ++SLGQGQ +AE + A K G+WV LQN HL W+ +E+ ++ ++
Sbjct: 3922 YTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSEN 3981
Query: 3622 DSAIKDTFRLFLSSMPS-----NTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFF 3676
FR+F+S+ P+ + P +L+NS+K+TNEPP G+ AN+ +A T
Sbjct: 3982 S---HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTL 4038
Query: 3677 EENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCK-EG 3735
E +++ I+F +C+FHA++ ER+KFGP GWN Y FN D ++ L + +
Sbjct: 4039 EMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANA 4098
Query: 3736 KIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFAPMAD 3795
K+P+D L Y+ GEI YGG +TD WD+R RT L F PE LE + + + P
Sbjct: 4099 KVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG--FPLPGNM 4156
Query: 3796 SLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSSTG--GEGKS 3853
+ YI+ + P ++G+H NA + F + + L T+LE+QPR S G G +
Sbjct: 4157 DYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGAT 4216
Query: 3854 NDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLT---TVLGQEVDRFNNLLK 3910
+E V+ L+ + RV ++ + +L ++ T V QE R N L +
Sbjct: 4217 REEKVKALLEEILERVTDEFN---------IPELMAKVEERTPYIVVAFQECGRMNILTR 4267
Query: 3911 LIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILR 3970
I SL L + G + M+ ME + N+ + VP W+ AYPS L +W DL+ R
Sbjct: 4268 EIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNR 4327
Query: 3971 TSFVDLWL-KRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQ 4029
++ W P + W++GFF PQ FLT +Q+ ARK P+D+++ + + R++
Sbjct: 4328 IKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREE 4387
Query: 4030 AAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVL 4089
P +G +HG+FM+ + WD + +I +A + P +
Sbjct: 4388 FR--------------------SPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPM 4427
Query: 4090 PVVHFEP-QQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAK 4148
PV+ + + + ++Y CP+YKT R T +V T L +K + W+
Sbjct: 4428 PVMFIKAIPADKQDCRSVYSCPVYKTSQRGPT---------YVWTFNLKTKENPSKWVLA 4478
Query: 4149 GSALLCQL 4156
G ALL Q+
Sbjct: 4479 GVALLLQI 4486
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 2027 bits (5252), Expect = 0.0
Identities = 1240/3746 (33%), Positives = 1979/3746 (52%), Gaps = 219/3746 (5%)
Query: 480 IQKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLE-----DFL 534
I + +E + K + +++ DES+ P+F + L L F P+LE FL
Sbjct: 875 IDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFL 934
Query: 535 DGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFH 594
I G VN N +P L D +N K++ ED+ +
Sbjct: 935 ALIEGLVNDIYNVARLIPRLAKDR---------MNYKMD-------------LEDNTDLI 972
Query: 595 TIISQIKETIQAAFESARIYAATFEKFQIFFKEN-----------------ESLDL---Q 634
+ ++ + A + A Y +FE++ + +N E LD
Sbjct: 973 EMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDD 1032
Query: 635 ALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNV-GLLLIDTRLLREKLIPSPLRCLEV 693
+ P + F EQ++ Y K +++ T+ G L D R ++ L+ + R
Sbjct: 1033 TIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW--- 1089
Query: 694 LNFMLPRQSKKKVDAIIFEAQDAEYKLEFV----PTTTTEY---VHSLLFLDEIQERIES 746
FM R V + + + A K+ + P +Y V + L +++ER +
Sbjct: 1090 -GFMFKRHLSNHVTNSLADLE-AFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAA 1147
Query: 747 LEDEGNIVTQMYKLMEQYQVPTPPEDFAV-------FATMKPSIVAVRNAIDKSVGDRES 799
++ + Q +L++ Y P E +A K + V+ + + S
Sbjct: 1148 TDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVS 1207
Query: 800 SIKQFCVHLGSDLEELNNEVN-EVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKR 858
+++ C E E DP Q K ++ ++ ++ L K
Sbjct: 1208 ILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKS---ISAMEGIMEALSKS 1264
Query: 859 AFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEV 918
F+V V ++ L+ E++L + LWD + ++W +K+ ++ E
Sbjct: 1265 GGL-------FEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1317
Query: 919 LNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQ 978
++ K+AK + L+K + L V+ + L + +L+NP ++ RHW + Q
Sbjct: 1318 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1377
Query: 979 TVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFV 1038
+E TL L QL++ + E+++I +A E+ +E +LK ++ +W EF
Sbjct: 1378 ATQVKFKMSE-ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ 1436
Query: 1039 ILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTL 1098
PH + +L ++ + L+D+ + + L S+YL V WQ++L+ + +
Sbjct: 1437 HEPHPRT-GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVI 1495
Query: 1099 EEWLTCQRNWLYLESIF-NAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQ 1157
W QR W +LESIF + DI+ QLP +++ F +++ +K +M + PN + A ++
Sbjct: 1496 SIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSK 1555
Query: 1158 PGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHL 1217
PGL + L +K L YLE+KR+ FPRFYF+S+ +LL+IL+ +P V HL
Sbjct: 1556 PGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHL 1615
Query: 1218 RKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNV 1277
K FDS+ KL+F L +P KV L M S E E + + G V
Sbjct: 1616 SKLFDSLCKLKFRL---------DASDKPLKVG----LGMYSKEDEYMVFDQECDLSGQV 1662
Query: 1278 EEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECL 1337
E WL +V + M ++LR A+ Y+ K R W++ +P+QV LT +QI W ++
Sbjct: 1663 EVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWIL-DYPAQVALTCTQIWWTTEVGLAF 1721
Query: 1338 ETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQ 1397
+ A++++ K +LN L ++ G+L R + + TIDVHARD+V +++
Sbjct: 1722 ARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIV 1781
Query: 1398 SKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLC 1457
+KVE+ ++F WQ QLR+ WD + +C A + +Q Y YEYLG PRLVITPLTDRCY+
Sbjct: 1782 AKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYIT 1841
Query: 1458 LMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQS 1517
L +L L +GGAPAGPAGTGKTETTKDL +AL VFNCS+ +DYK G + GLAQ+
Sbjct: 1842 LTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQT 1901
Query: 1518 GAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPG 1577
GAW CFDEFNRI +EVLSVIA Q+ +++A AK F F G I L+ T FITMNPG
Sbjct: 1902 GAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPG 1961
Query: 1578 YAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLS 1637
YAGR ELP+NLKALFRP AM+VP++ LI E++L +EGF +++LARK +Y LC E LS
Sbjct: 1962 YAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS 2021
Query: 1638 QQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIIS 1697
+QDHYD+G+RA+KSVLV+AGSLKR +P ED VL+RAL+D N+PK +TDD +F G+I
Sbjct: 2022 KQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIG 2081
Query: 1698 DLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGG 1757
DLFP + +P + I + LQ E V KV+Q E + VRH V +VG G
Sbjct: 2082 DLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGS 2141
Query: 1758 GKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLM 1817
GK+ V + L +T NL++ + L+PK++T EL+G +N +T EWKDGL
Sbjct: 2142 GKSQVLKSLNKTYQNLKRKPV---------AVDLDPKAVTCDELFGIINPVTREWKDGLF 2192
Query: 1818 ALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLF 1877
+ +R N T + KWII DG +D +WIE++NTV+DDNK+L LA++ERI L + ++F
Sbjct: 2193 STIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVF 2252
Query: 1878 EVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVD 1937
E+ LR A+PATVSR G+++++P +L W P V +W I ++ + + ++ LF +Y+
Sbjct: 2253 EISHLRTATPATVSRAGILYINPADLGWNPVVSSW---IERRKVQSEKANLMILFDKYLP 2309
Query: 1938 EGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCY 1997
L + + P +I+ + T+ LLE L+ K + + FVF
Sbjct: 2310 TCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEK-----TVPPDSPRELYELYFVFTC 2364
Query: 1998 LWSLGGNLTENYYDSFDT-FIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPT 2056
W+ GG + ++ + F + ++ + P+ G ++ ++D DTK+ PW +P+
Sbjct: 2365 FWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPS 2424
Query: 2057 FKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQES 2116
F+ + DVP LV TT+T+R Y M+ L+ V+ G G GKSV+ L + +
Sbjct: 2425 FELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESL-NT 2483
Query: 2117 AGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGS 2176
Y+ + F+ T+SA Q ++E LE+K G PG K++V F+DD+NMP +D+YG+
Sbjct: 2484 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2543
Query: 2177 QPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLP 2236
P L+RQ+ D +YDR+KL K+I + + AC P G + R RHF + +
Sbjct: 2544 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYV-ACMNPTSGSFTIDSRLQRHFCVFAVS 2602
Query: 2237 MPSEHSLKQIFQAILNGFLS--DFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYV 2294
P + +L I+ IL L+ A+++ +S +V A++ ++ K++ LPT K HYV
Sbjct: 2603 FPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYV 2662
Query: 2295 FNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMA 2354
FNLRDLS QG+L ++ + + RL+ HE +RV+ D++++ +D+ H +
Sbjct: 2663 FNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMAST 2722
Query: 2355 NKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNP 2414
K F D E KP I F F D Y + D+ +L D LD YN N
Sbjct: 2723 KKFFDDLGD-ELLFAKPNI---FCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVN- 2777
Query: 2415 KEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELS 2474
+ LV F+DA+ H+ RI R++ RGNALLVGVGG+GKQSL+RLAA+I G QI L
Sbjct: 2778 AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLK 2837
Query: 2475 RGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKD 2534
+GY DL Y A V++ VFL TD+Q+ E+FL IN++L SGE+P LF +D
Sbjct: 2838 KGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMED 2897
Query: 2535 ELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPS 2594
E+E ++++ RP+ K +G+++ R+ +++FI KVR++L ++LC SPVG R R R FP+
Sbjct: 2898 EVENIISSMRPQVKSLGMND-TRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPA 2956
Query: 2595 LVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYN 2654
+VNC IDWF +WP +AL+SVS F + + G +K + VH +V+ M+ Y
Sbjct: 2957 VVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPVIKASISFFMSYVHTTVNEMSRVYLA 3015
Query: 2655 ELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLS 2714
RR YTTP ++LE I LY ++L++KR ++++ +R++NGL KL T VD +K L+
Sbjct: 3016 TERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3075
Query: 2715 ALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLD 2774
E L K+E + L++ + ++ E + + ++E +V + + DL
Sbjct: 3076 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLA 3135
Query: 2775 EALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISIL------LNAKPDWPSA 2828
+A PAL AA +ALD+L+K +++E++ F PPD V+ V A+ IL + W +A
Sbjct: 3136 KAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAA 3195
Query: 2829 KQLLGD-SNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRA 2887
K ++G FL L ++DKE+I L + Y NP F PE + S A +C W
Sbjct: 3196 KIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCIN 3255
Query: 2888 MDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEK 2947
+ + V V PKRQ L A AEL L + + ++ + L ++K EK
Sbjct: 3256 IVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEK 3315
Query: 2948 ESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYG 3007
+ T ++ A +L L E +RW ES++ F + + G+V + +A V+Y G
Sbjct: 3316 IKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVG 3375
Query: 3008 AFTAQYRQSLIE-CWIQDCQSLEIPIDPSFSL--INILGDPYEIRQWNTDGLPRDLISTE 3064
FT +YR L+E WI +L++PI + L +++L D ++ WN GLP D +STE
Sbjct: 3376 YFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTE 3435
Query: 3065 NGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLL 3124
N ++ RWPL++D Q Q +WI+NK +S LK I+L ++L ++E +I G +L+
Sbjct: 3436 NATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQKSYLDVIEQAISEGDTLLI 3494
Query: 3125 EELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCI 3184
E + ET+DP L+P+L + G I++GD +++Y FR + TK NPHY PE+
Sbjct: 3495 ENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQA 3552
Query: 3185 KVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLF 3244
+ T+INF VT+ GLEDQLL+ VV E+P LE+ + L N K LK +E+ +L L
Sbjct: 3553 QCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLS 3612
Query: 3245 TSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFV 3304
+ GN L + L++ L+ +K T+ I+ ++ EA+ TE IN ARE YRP A + S++YF+
Sbjct: 3613 AASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFI 3672
Query: 3305 IASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFE 3364
+ L++I+P+YQ+SLK F +F I+ + ++QR+ L ++ + Y+ +RGLFE
Sbjct: 3673 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3732
Query: 3365 QHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDL 3424
+ KLI+ + +++ + L+ E +F LR P +L W L
Sbjct: 3733 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKAL 3788
Query: 3425 EESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPW 3484
E F L +I + ++W+ + + +K + ++ W
Sbjct: 3789 SE-MDEFKNLDSDIEG--------------SAKRWKKLVESEAPEKEIFPKE-------W 3826
Query: 3485 SAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVF 3544
++ KL +++C + +++ +A+ +FV E +G +F+E V+ Y++ S +T + F
Sbjct: 3827 K-NKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3885
Query: 3545 ILSTGSDPMGAFQRFARESGY---SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNC 3601
ILS G DP+ + ++ G+ + ++ ++SLGQGQ +AE + A + G+WV LQN
Sbjct: 3886 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNI 3945
Query: 3602 HLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMP-----SNTFPVTVLQNSVKVTNEP 3656
HL W+ +++ ++ ++ + + +R+F+S+ P ++ P +L+N++K+TNEP
Sbjct: 3946 HLVARWLGTLDKKLERYS---TGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEP 4002
Query: 3657 PKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEF 3716
P G+ AN+ +A T E +++ ++F +C+FHA++ ER+KFG GWN Y F
Sbjct: 4003 PTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPF 4062
Query: 3717 NDSDRECALLNLKLYCKEG-KIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPE 3775
N+ D ++ L Y + K+PWD L Y+ GEI YGG +TD WD+R RT L + E
Sbjct: 4063 NNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTE 4122
Query: 3776 TLEEDYKYSESGIYFAPMADSLQEFKDYI-ENLPLIDDPEIFGMHENANLVFQYKETSTL 3834
LE D + G P D + + +YI ENLP + P ++G+H NA + F + L
Sbjct: 4123 MLEGDVLLA-PGFQIPPNLD-YKGYHEYIDENLP-PESPYLYGLHPNAEIGFLTVTSEKL 4179
Query: 3835 INTILEVQPR--SSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLN 3892
T+LE+QP+ S G G S +E V+ ++ + ++PE M K
Sbjct: 4180 FRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEK------T 4233
Query: 3893 SLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNT 3952
V QE +R N L + SL+ LN + G + ++ ++E + + + VP W
Sbjct: 4234 PYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVAR 4293
Query: 3953 AYPSLKPLGSWVKDLILRTSFVDLWLKR-GQPKSYWISGFFFPQGFLTGTLQNHARKYNL 4011
AYPS+ L +W DL+LR ++ W P + W++GFF PQ FLT +Q+ ARK
Sbjct: 4294 AYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEW 4353
Query: 4012 PIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWD 4071
P+D++ V R+ DM P P +G V+G+FM+ +RWD
Sbjct: 4354 PLDKMCLSVEVTKKNRE-------------------DMTAP-PREGSYVYGLFMEGARWD 4393
Query: 4072 DKEMVIEDALPGQMNPVLPVVHFEP-QQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNF 4130
+ VI +A ++ P +PV+ + + + +Y CP+YKT R T +
Sbjct: 4394 TQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPT---------Y 4444
Query: 4131 VVTVLLPSKRSKDYWIAKGSALLCQL 4156
V T L +K WI ALL Q+
Sbjct: 4445 VWTFNLKTKEKAAKWILAAVALLLQV 4470
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 1993 bits (5163), Expect = 0.0
Identities = 1179/3360 (35%), Positives = 1844/3360 (54%), Gaps = 168/3360 (5%)
Query: 845 LNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQ 904
L+ L L++ Q + + F+V + +++ +++ E+KL + LWD +
Sbjct: 1282 LDKANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSID 1341
Query: 905 EWLKSKFDCLDPEVLNGQVSKYAKF-----VTQLEKGLPPNSVVPQLKYKVEKMKEKLPV 959
W K+++ + E ++ ++ ++AK + L K + L+ V+ M L
Sbjct: 1342 NWTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRA 1401
Query: 960 IIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEA 1019
I +L++P L+ RHW + + + + E TL L L + +++ I +A E
Sbjct: 1402 ITELQSPALRDRHWHQLMKAIGVKFLINEAT-TLADLLALRLHRVEDDVRRIVDKAVKEL 1460
Query: 1020 ALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGP 1079
E ++ ++ +W T +F H + + +L + + L+ + + + TL S+Y+
Sbjct: 1461 GTEKVITEISQTWATMKFSYEVHYRT-GIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEY 1519
Query: 1080 LKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFN-APDIQRQLPAEAKMFLQVDKSW 1138
+V WQ +L + + + W+ QR W +LESIF + DI+ QL +A+ F VD +
Sbjct: 1520 FIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEF 1579
Query: 1139 KEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSND 1198
KE+M K ++ N L A +P L E ++ + L +K L YLE+KR+ FPRFYF+S+
Sbjct: 1580 KELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSA 1639
Query: 1199 ELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAML 1258
+LL+IL++ P+ V HL K FDSI+ L+F + + V + + M
Sbjct: 1640 DLLDILSKGAQPKQVTCHLAKLFDSIADLQFE--------------DNQDVSAHRAVGMY 1685
Query: 1259 SPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPS 1318
S E E V + G+VE WL ++E+ M ++R AI Y+ K R W+ P+
Sbjct: 1686 SKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIF-DFPA 1744
Query: 1319 QVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNIL 1378
QV LT SQI W D+ + ALK+F K +LN L ++ G LP R +
Sbjct: 1745 QVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKI 1804
Query: 1379 TALITIDVHARDIVTELVQSK--VETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGY 1436
+ TIDVHARD+V +L+ K V + ++F W QLR+ W+ +C + +Q+ Y Y
Sbjct: 1805 MTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFY 1864
Query: 1437 EYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVF 1496
EYLG PRLVITPLTDRCY+ L +L L + GAPAGPAGTGKTETTKDL +AL + VF
Sbjct: 1865 EYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVF 1924
Query: 1497 NCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFM 1556
NCS+ +DYK +G + GL Q+GAW CFDEFNRI +EVLSV+A Q+ I +A + RF+
Sbjct: 1925 NCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFV 1984
Query: 1557 FEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFE 1616
F G I L + FITMNPGYAGRTELP+NLKALFRP AM+ P+ LI E++L +EGF
Sbjct: 1985 FLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFV 2044
Query: 1617 SSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRAL 1676
++ LARK +Y LC E LS+QDHYD+G+RA+KSVLV+AGSLKR + + ED VL+RAL
Sbjct: 2045 DARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRAL 2104
Query: 1677 QDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKV 1736
+D N+PK +TDD +F G++ DLFP + +P + + LQPE + KV
Sbjct: 2105 RDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKV 2164
Query: 1737 IQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSI 1796
+Q E + VRH V +VG G GK+ + R L T N+++ + N LNPK++
Sbjct: 2165 VQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWND---------LNPKAV 2215
Query: 1797 TMGELYGEVNNLTLEWKDGLMALS---------VRAAVNDTSEDHKWIISDGPVDALWIE 1847
T EL+G +++ T EWKDG + S +R N + KWI+ DG +D +WIE
Sbjct: 2216 TTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIE 2275
Query: 1848 NMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMP 1907
++NTV+DDNK+L LA++ERI LTP + +LFE+ LR A+PATVSR G+++V+P++L W P
Sbjct: 2276 SLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNP 2335
Query: 1908 YVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLE 1967
YV +W I ++ + + + LF +YV L + + S V TLC LLE
Sbjct: 2336 YVASW---IDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLE 2392
Query: 1968 SLILGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDT-FIRTQFDDNPD 2026
L+ + N+ + K + FVF +W+ GG L ++ + F R +
Sbjct: 2393 CLLTPE---NVPSDSPK--EVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKA 2447
Query: 2027 ARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLL 2086
+ P+ G ++ ++D TK+L PW I F + DVP +LV TT+T R Y ME LL
Sbjct: 2448 VKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELLL 2507
Query: 2087 AVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERK 2146
++ G GVGK+V L + E Y+ + F+ T+S Q+I+E LE+K
Sbjct: 2508 EKGKPLMLVGNAGVGKTVFVGDTLASLSED--YIVSRVPFNYYTTSTALQKILEKPLEKK 2565
Query: 2147 RKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDV 2206
+ G GNK+++ F+DD+NMP +D YG+ P L+RQ+ D+G +YDR K+ KEI +
Sbjct: 2566 AGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNC 2625
Query: 2207 TIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSD--FPPAVKQ 2264
+ AC P G + PR RHF++ PS +L I+ I + F P++ +
Sbjct: 2626 QYV-ACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILR 2684
Query: 2265 TASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRL 2324
+ ++++A++ + M + LPT K HY+FNLRDLS QGIL P ++ + + L
Sbjct: 2685 SGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHL 2744
Query: 2325 FCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADK 2384
+ HE RV+ D+LI+ +D F + E A K+F ID L +P+I+ F G D
Sbjct: 2745 WLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFE-GIDSHMLLQQPLIYCHFADRGKDP 2803
Query: 2385 ADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNAL 2444
Y + D E +L + LD+YN N + LV F+DA++HV RI+R++R +G AL
Sbjct: 2804 H---YMPVKDWEVLKTILTETLDNYNELN-AAMHLVLFEDAMQHVCRISRILRTPQGCAL 2859
Query: 2445 LVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLF 2504
LVGVGG+GKQSL+RLAA++ G + QI L+ GY DL LY G ++ VFL
Sbjct: 2860 LVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLL 2919
Query: 2505 TDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYF 2564
TD Q++ E FL IN++L SGE+P+LF ++++++++ +G+ + +R+ +++F
Sbjct: 2920 TDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVD-SRENCWKFF 2978
Query: 2565 ISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVD 2624
+++VR +L I+LC SPVG R R R FP++VNC IDWF WP+EAL+SVS+ F +
Sbjct: 2979 MARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETK 3038
Query: 2625 AGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQ 2684
K+ + L +VH +V+ M+ RYY RR YTTP S+LE I+L+ ++L +K+ +
Sbjct: 3039 GIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNE 3098
Query: 2685 IISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQV 2744
+ ++R+ NG+ KL T V +K L++ E L ++ D EAL+ K+ + E +
Sbjct: 3099 VSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSRE 3158
Query: 2745 RNTVQEDEATAKVKAEETQAIAD--DAQRDLDEALPALDAANKALDSLDKADISEIRVFT 2802
+ +E KV A +T+ + + DL +A PAL AA AL++L++ ++SE++ F
Sbjct: 3159 KTIADAEE--RKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFP 3216
Query: 2803 KPPDLVMTVMEAISILLNAK------PDWPSAKQLLGD-SNFLKRLLEYDKENIKPQILA 2855
PP V V A+ +LL + W +AK +G +FL+ L+ YDKE+I L
Sbjct: 3217 NPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLK 3276
Query: 2856 KL-QKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDI 2914
+ + Y+ +P+F P + S A +C WV + + V VEPKRQ L A EL
Sbjct: 3277 VVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAA 3336
Query: 2915 TMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDE 2974
L + L ++ + L ++K EK + + T + A +L LE +
Sbjct: 3337 ATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAK 3396
Query: 2975 QVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIEC-WIQDC-QSLEIPI 3032
++RW +SI+ FE + + G+V + AA V+Y G FT QYRQ L+ C W+ Q + IP+
Sbjct: 3397 KIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPL 3456
Query: 3033 DPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNK 3092
LI++L D I WN +GLP D +STEN ++T RWPL+IDPQ Q +WI+NK
Sbjct: 3457 TEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNK 3516
Query: 3093 ESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLI 3152
LK+ L FL +E ++ G +L+E L+ET+DP L+P+L + G I
Sbjct: 3517 YGMD-LKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKG--KYI 3573
Query: 3153 RLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKP 3212
R+GD + +++KNFR + TK+ NPHY PE+ + T++NFTVT+ GLE QLL++VV +E+P
Sbjct: 3574 RIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERP 3633
Query: 3213 RLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKT 3272
LE+ ++ L N K +LK +E+ +L L +EG+ LD+ +L++ L+ +K T I+
Sbjct: 3634 DLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEH 3693
Query: 3273 RLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIET 3332
++ EA+ E+ IN ARE YRPVA + S++YFVI L +I+P+YQ+SLK F LF+ IE
Sbjct: 3694 KVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQ 3753
Query: 3333 SVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNF 3392
+ K E++Q R+ +L+E ++ S+ LFE+ KL + + +++ ++ + E +F
Sbjct: 3754 ADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDF 3813
Query: 3393 FLRGSAGLEKERPPKPEAPWLPTATWF---ACCDLEESFPVFHGLTQNILSHPISIRLGS 3449
LR + E +L + +W A +EE F G+ +++ GS
Sbjct: 3814 LLRFTV----EHTHLSPVDFLTSQSWSAIKAIAVMEE----FRGIDRDV--------EGS 3857
Query: 3450 FETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFAL 3509
+ + +KW + EKE Q+ W S KLIL++ + +++ +AL
Sbjct: 3858 AKQW---RKWV---------ESECPEKEKLPQE-WKK-KSLIQKLILLRAMRPDRMTYAL 3903
Query: 3510 TDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGY---S 3566
+FV E LG +++E +DL +++ S TP+ FILS G D + + + G+ S
Sbjct: 3904 RNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDS 3963
Query: 3567 ERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIK 3626
+ ++SLGQGQ +AE ++ A K G+WV LQN HL W+ +E+L++ F+
Sbjct: 3964 GKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHR-- 4021
Query: 3627 DTFRLFLSSMPSNT-----FPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFFEENIL 3681
+R+F+S+ + T P +L+NS+K+TNEPP G+ AN+ A E
Sbjct: 4022 -DYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSK 4080
Query: 3682 GKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRE-CALLNLKLYCKEGKIPWD 3740
++++ I+F +C+FHA + R +FGP GW+ Y FN D CA + K+PW+
Sbjct: 4081 EQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWE 4140
Query: 3741 ALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFAPMADSLQEF 3800
L Y+ GEI YGG +TD WD++ R L+ F +P E++ + + AP +
Sbjct: 4141 DLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPG--FAAPPYLDYAGY 4198
Query: 3801 KDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSSTGGE--GKSNDEIV 3858
YIE + + P ++G+H NA + F ++TL T+LE+QPR++ G+ G+S +E V
Sbjct: 4199 HQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKV 4258
Query: 3859 QELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLET 3918
+ ++ + ++PE+ M + + V QE +R N L++ I SLE
Sbjct: 4259 KNVLDDILEKLPEEFNMAE------IMQKNSNRSPYVLVCFQECERMNILIREIRISLEQ 4312
Query: 3919 LNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWL 3978
L+ ++ G + +S +E + + VP WS AYPS L W DL+LR +D W
Sbjct: 4313 LDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWT 4372
Query: 3979 K-RGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAK 4037
+ P W+SGFF PQ FLT +Q ARK P+D+ V ++
Sbjct: 4373 QDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKE--------- 4423
Query: 4038 TVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFE-- 4095
+G P +G +HG+FM+ +RWD + I +A ++ +PV+ +
Sbjct: 4424 --DYGH---------PPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKAT 4472
Query: 4096 PQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQ 4155
P + T Y CP+Y+T R +++ T L S+ W+ G ALL +
Sbjct: 4473 PVDRQETKQT-YECPVYRTKLR---------GPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1989 bits (5154), Expect = 0.0
Identities = 1240/3777 (32%), Positives = 1975/3777 (52%), Gaps = 257/3777 (6%)
Query: 480 IQKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLE-----DFL 534
I + +E + K + +++ DES+ P+F + L L F P+LE FL
Sbjct: 866 IDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFL 925
Query: 535 DGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFH 594
I G VN N +P L D +N K++ ED+ +
Sbjct: 926 ALIEGLVNDIYNVARLIPRLAKDR---------MNYKMD-------------LEDNTDLI 963
Query: 595 TIISQIKETIQAAFESARIYAATFEKFQIFFKEN-----------------ESLDL---Q 634
+ ++ + A + A Y +FE++ + +N E LD
Sbjct: 964 EMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDD 1023
Query: 635 ALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNV-GLLLIDTRLLREKLIPSPLRCLEV 693
+ P + F EQ++ Y K +++ T+ G L D R ++ L+ + R
Sbjct: 1024 TIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW--- 1080
Query: 694 LNFMLPRQSKKKVDAIIFEAQDAEYKLEFV----PTTTTEY---VHSLLFLDEIQERIES 746
FM R V + + + A K+ + P +Y V + L +++ER +
Sbjct: 1081 -GFMFKRHLSNHVTNSLADLE-AFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAA 1138
Query: 747 LEDEGNIVTQMYKLMEQYQVPTPPEDFAV-------FATMKPSIVAVRNAIDKSVGDRES 799
++ + Q +L++ Y P E +A K + V+ + + S
Sbjct: 1139 TDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVS 1198
Query: 800 SIKQFCVHLGSDLEELNNEVN-EVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKR 858
+++ C E E DP +K+ L L+ ++ L K
Sbjct: 1199 ILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYK---SLNKVFL----LKGIMEALSKS 1251
Query: 859 AFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEV 918
F+V V ++ L+ E++L + LWD + ++W +K+ ++ E
Sbjct: 1252 GGL-------FEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1304
Query: 919 LNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQ 978
++ K+AK + L+K + L V+ + L + +L+NP ++ RHW + Q
Sbjct: 1305 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1364
Query: 979 TVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFV 1038
+E TL L QL++ + E+++I +A E+ +E +LK ++ +W EF
Sbjct: 1365 ATQVKFKMSE-ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ 1423
Query: 1039 ILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTL 1098
PH + +L ++ + L+D+ + + L S+YL V WQ++L+ + +
Sbjct: 1424 HEPHPRT-GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVI 1482
Query: 1099 EEWLTCQRNWLYLESIF-NAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQ 1157
W QR W +LESIF + DI+ QLP +++ F +++ +K +M + PN + A ++
Sbjct: 1483 SIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSK 1542
Query: 1158 PGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHL 1217
PGL + L +K L YLE+KR+ FPRFYF+S+ +LL+IL+ +P V HL
Sbjct: 1543 PGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHL 1602
Query: 1218 RKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNV 1277
K FDS+ KL+F L +P KV L M S E E + + G V
Sbjct: 1603 SKLFDSLCKLKFRL---------DASDKPLKVG----LGMYSKEDEYMVFDQECDLSGQV 1649
Query: 1278 EEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECL 1337
E WL +V + M ++LR A+ Y+ K R W++ +P+Q I W ++
Sbjct: 1650 EVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWIL-DYPAQ-------IWWTTEVGLAF 1701
Query: 1338 ETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQ 1397
+ A+K++ K +LN L ++ G+L R + + TIDVHARD+V +++
Sbjct: 1702 ARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI- 1760
Query: 1398 SKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLC 1457
VE+ ++F WQ QLR+ WD + +C A + +Q Y YEYLG PRLVITPLTDRCY+
Sbjct: 1761 --VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYIT 1818
Query: 1458 LMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQS 1517
L +L L +GGAPAGPAGTGKTETTKDL +AL VFNCS+ +DYK G + GLAQ+
Sbjct: 1819 LTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQT 1878
Query: 1518 GAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPG 1577
GAW CFDEFNRI +EVLSVIA Q+ +++A AK F F G I L+ T FITMNPG
Sbjct: 1879 GAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPG 1938
Query: 1578 YAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLS 1637
YAGR ELP+NLKALFRP AM+VP++ LI E++L +EGF +++LARK +Y LC E LS
Sbjct: 1939 YAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS 1998
Query: 1638 QQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIIS 1697
+QDHYD+G+RA+KSVLV+AGSLKR +P ED VL+RAL+D N+PK +TDD +F G+I
Sbjct: 1999 KQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIG 2058
Query: 1698 DLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGG 1757
DLFP + +P + I + LQ E V KV+Q E + VRH V +VG G
Sbjct: 2059 DLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGS 2118
Query: 1758 GKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLM 1817
GK+ V + L +T NL++ + L+PK++T EL+G +N +T EWKDGL
Sbjct: 2119 GKSQVLKSLNKTYQNLKRKPV---------AVDLDPKAVTCDELFGIINPVTREWKDGLF 2169
Query: 1818 ALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLF 1877
+ +R N T + KWII DG +D +WIE++NTV+DDNK+L LA++ERI L + ++F
Sbjct: 2170 STIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVF 2229
Query: 1878 EVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVD 1937
E+ LR A+PATVSR G+++++P +L W P V +W I ++ + + ++ LF +Y+
Sbjct: 2230 EISHLRTATPATVSRAGILYINPADLGWNPVVSSW---IERRKVQSEKANLMILFDKYLP 2286
Query: 1938 EGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCY 1997
L + + P +I+ + T+ LLE L+ K + + FVF
Sbjct: 2287 TCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEK-----TVPPDSPRELYELYFVFTC 2341
Query: 1998 LWSLGGNLTENYYDSFDT-FIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPT 2056
W+ GG + ++ + F + ++ + P+ G ++ ++D DTK+ PW +P+
Sbjct: 2342 FWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPS 2401
Query: 2057 FKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQES 2116
F+ + DVP LV TT+T+R Y M+ L+ V+ G G GKSV+ L + +
Sbjct: 2402 FELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESL-NT 2460
Query: 2117 AGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGS 2176
Y+ + F+ T+SA Q ++E LE+K G PG K++V F+DD+NMP +D+YG+
Sbjct: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520
Query: 2177 QPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLP 2236
P L+RQ+ D +YDR+KL K+I + + AC P G + R RHF + +
Sbjct: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYV-ACMNPTSGSFTIDSRLQRHFCVFAVS 2579
Query: 2237 MPSEHSLKQIFQAILNGFLS--DFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYV 2294
P + +L I+ IL L+ A+++ +S +V A++ ++ K++ LPT K HYV
Sbjct: 2580 FPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYV 2639
Query: 2295 FNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMA 2354
FNLRDLS QG+L ++ + + RL+ HE +RV+ D++++ +D+ H +
Sbjct: 2640 FNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMAST 2699
Query: 2355 NKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNP 2414
K F D E KP I F F D Y + D+ +L D LD YN N
Sbjct: 2700 KKFFDDLGD-ELLFAKPNI---FCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVN- 2754
Query: 2415 KEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELS 2474
+ LV F+DA+ H+ RI R++ RGNALLVGVGG+GKQSL+RLAA+I G QI L
Sbjct: 2755 AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLK 2814
Query: 2475 RGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKD 2534
+GY DL Y A V++ VFL TD+Q+ E+FL IN++L SGE+P LF +D
Sbjct: 2815 KGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMED 2874
Query: 2535 ELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPS 2594
E+E ++++ RP+ K +G+++ R+ +++FI KVR++L ++LC SPVG R R R FP+
Sbjct: 2875 EVENIISSMRPQVKSLGMND-TRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPA 2933
Query: 2595 LVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYN 2654
+VNC IDWF +WP +AL+SVS F + + E+K + VH +V+ M+ Y
Sbjct: 2934 VVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLA 2993
Query: 2655 ELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLS 2714
RR YTTP ++LE I LY ++L++KR ++++ +R++NGL KL T VD +K L+
Sbjct: 2994 TERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3053
Query: 2715 ALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLD 2774
E L K+E + L++ + ++ E + + ++E +V + + DL
Sbjct: 3054 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLA 3113
Query: 2775 EALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISIL------LNAKPDWPSA 2828
+A PAL AA +ALD+L+K +++E++ F PPD V+ V A+ IL + W +A
Sbjct: 3114 KAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAA 3173
Query: 2829 KQLLGD-SNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRA 2887
K ++G FL L ++DKE+I L + Y NP F PE + S A +C W
Sbjct: 3174 KIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCIN 3233
Query: 2888 MDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEK 2947
+ + V V PKRQ L A AEL L + + ++ + L ++K EK
Sbjct: 3234 IVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEK 3293
Query: 2948 ESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYG 3007
+ T ++ A +L L E +RW ES++ F + + G+V + +A V+Y G
Sbjct: 3294 IKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVG 3353
Query: 3008 AFTAQYRQSLIE-CWIQDCQSLEIPIDPSFSL--INILGDPYEIRQWNTDGLPRDLISTE 3064
FT +YR L+E WI +L++PI + L +++L D ++ WN GLP D +STE
Sbjct: 3354 YFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTE 3413
Query: 3065 NGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLL 3124
N ++ RWPL++D Q Q +WI+NK +S LK I+L ++L ++E +I G +L+
Sbjct: 3414 NATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQKSYLDVIEQAISEGDTLLI 3472
Query: 3125 EELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCI 3184
E + ET+DP L+P+L + G I++GD +++Y FR + TK NPHY PE+
Sbjct: 3473 ENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQA 3530
Query: 3185 KVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLF 3244
+ T+INF VT+ GLEDQLL+ VV E+P LE+ + L N K LK +E+ +L L
Sbjct: 3531 QCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLS 3590
Query: 3245 TSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFV 3304
+ GN L + L++ L+ +K T+ I+ ++ EA+ TE IN ARE YRP A + S++YF+
Sbjct: 3591 AASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFI 3650
Query: 3305 IASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFE 3364
+ L++I+P+YQ+SLK F +F I+ + ++QR+ L ++ + Y+ +RGLFE
Sbjct: 3651 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3710
Query: 3365 QHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDL 3424
+ KLI+ + +++ + L+ E +F LR P +L W L
Sbjct: 3711 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKAL 3766
Query: 3425 EESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPW 3484
E F L +I + ++W+ + + +K + ++ W
Sbjct: 3767 SE-MDEFKNLDSDIEG--------------SAKRWKKLVESEAPEKEIFPKE-------W 3804
Query: 3485 SAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVF 3544
++ KL +++C + +++ +A+ +FV E +G +F+E V+ Y++ S +T + F
Sbjct: 3805 K-NKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3863
Query: 3545 ILSTGSDPMGAFQRFARESGY---SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQ-- 3599
ILS G DP+ + ++ G+ + ++ ++SLGQGQ +AE + A + G+WV LQ
Sbjct: 3864 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVR 3923
Query: 3600 ------NCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMP-----SNTFPVTVLQN 3648
N HL W+ +++ ++ ++ + + +R+F+S+ P ++ P +L+N
Sbjct: 3924 GGQHCRNIHLVARWLGTLDKKLERYS---TGSHEDYRVFISAEPAPSPETHIIPQGILEN 3980
Query: 3649 SVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPL 3708
++K+TNEPP G+ AN+ +A T E +++ ++F +C+FHA++ ER+KFG
Sbjct: 3981 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4040
Query: 3709 GWNICYEFNDSDRECALLNLKLYCKEG-KIPWDALIYITGEITYGGRVTDSWDQRCLRTI 3767
GWN Y FN+ D ++ L Y + K+PWD L Y+ GEI YGG +TD WD+R RT
Sbjct: 4041 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTY 4100
Query: 3768 LKRFFSPETLEEDYKYSESGIYFAPMADSLQEFKDYI-ENLPLIDDPEIFGMHENANLVF 3826
L + E LE D + G P D + + +YI ENLP + P ++G+H NA + F
Sbjct: 4101 LAEYIRTEMLEGDVLLA-PGFQIPPNLD-YKGYHEYIDENLP-PESPYLYGLHPNAEIGF 4157
Query: 3827 QYKETSTLINTILEVQPR--SSTGGEGKSNDEIVQELVASVQTRVPEKLE---------- 3874
+ L T+LE+QP+ S G G S +E L R E LE
Sbjct: 4158 LTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTG 4217
Query: 3875 ----------MEGASESLFVKDLQGRLNSLT---TVLGQEVDRFNNLLKLIHTSLETLNK 3921
+E E+ + ++ + T V QE +R N L + SL+ LN
Sbjct: 4218 FQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNL 4277
Query: 3922 AIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKR- 3980
+ G + ++ ++E + + + VP W AYPS+ L +W DL+LR ++ W
Sbjct: 4278 GLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDF 4337
Query: 3981 GQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQ 4040
P + W++GFF PQ FLT +Q+ ARK P+D++ V R+
Sbjct: 4338 ALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNRE------------ 4385
Query: 4041 FGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEP-QQN 4099
DM P P +G V+G+FM+ +RWD + VI +A ++ P +PV+ + +
Sbjct: 4386 -------DMTAP-PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVD 4437
Query: 4100 YKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQL 4156
+ +Y CP+YKT R T +V T L +K WI ALL Q+
Sbjct: 4438 RMETKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1989 bits (5153), Expect = 0.0
Identities = 1239/3777 (32%), Positives = 1975/3777 (52%), Gaps = 257/3777 (6%)
Query: 480 IQKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLE-----DFL 534
I + +E + K + +++ DES+ P+F + L L F P+LE FL
Sbjct: 866 IDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFL 925
Query: 535 DGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFH 594
I G VN N +P L D +N K++ ED+ +
Sbjct: 926 ALIEGLVNDIYNVARLIPRLAKDR---------MNYKMD-------------LEDNTDLI 963
Query: 595 TIISQIKETIQAAFESARIYAATFEKFQIFFKEN-----------------ESLDL---Q 634
+ ++ + A + A Y +FE++ + +N E LD
Sbjct: 964 EMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDD 1023
Query: 635 ALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNV-GLLLIDTRLLREKLIPSPLRCLEV 693
+ P + F EQ++ Y K +++ T+ G L D R ++ L+ + R
Sbjct: 1024 TIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW--- 1080
Query: 694 LNFMLPRQSKKKVDAIIFEAQDAEYKLEFV----PTTTTEY---VHSLLFLDEIQERIES 746
FM R V + + + A K+ + P +Y V + L +++ER +
Sbjct: 1081 -GFMFKRHLSNHVTNSLADLE-AFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAA 1138
Query: 747 LEDEGNIVTQMYKLMEQYQVPTPPEDFAV-------FATMKPSIVAVRNAIDKSVGDRES 799
++ + Q +L++ Y P E +A K + V+ + + S
Sbjct: 1139 TDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVS 1198
Query: 800 SIKQFCVHLGSDLEELNNEVN-EVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKR 858
+++ C E E DP +K+ L L+ ++ L K
Sbjct: 1199 ILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYK---SLNKVFL----LKGIMEALSKS 1251
Query: 859 AFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEV 918
F+V V ++ L+ E++L + LWD + ++W +K+ ++ E
Sbjct: 1252 GGL-------FEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1304
Query: 919 LNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQ 978
++ K+AK + L+K + L V+ + L + +L+NP ++ RHW + Q
Sbjct: 1305 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1364
Query: 979 TVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFV 1038
+E TL L QL++ + E+++I +A E+ +E +LK ++ +W EF
Sbjct: 1365 ATQVKFKMSE-ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ 1423
Query: 1039 ILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTL 1098
PH + +L ++ + L+D+ + + L S+YL V WQ++L+ + +
Sbjct: 1424 HEPHPRT-GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVI 1482
Query: 1099 EEWLTCQRNWLYLESIF-NAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQ 1157
W QR W +LESIF + DI+ QLP +++ F +++ +K +M + PN + A ++
Sbjct: 1483 SIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSK 1542
Query: 1158 PGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHL 1217
PGL + L +K L YLE+KR+ FPRFYF+S+ +LL+IL+ +P V HL
Sbjct: 1543 PGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHL 1602
Query: 1218 RKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNV 1277
K FDS+ KL+F L +P KV L M S E E + + G V
Sbjct: 1603 SKLFDSLCKLKFRL---------DASDKPLKVG----LGMYSKEDEYMVFDQECDLSGQV 1649
Query: 1278 EEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECL 1337
E WL +V + M ++LR A+ Y+ K R W++ +P+Q I W ++
Sbjct: 1650 EVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWIL-DYPAQ-------IWWTTEVGLAF 1701
Query: 1338 ETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQ 1397
+ A++++ K +LN L ++ G+L R + + TIDVHARD+V +++
Sbjct: 1702 ARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMI- 1760
Query: 1398 SKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLC 1457
VE+ ++F WQ QLR+ WD + +C A + +Q Y YEYLG PRLVITPLTDRCY+
Sbjct: 1761 --VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYIT 1818
Query: 1458 LMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQS 1517
L +L L +GGAPAGPAGTGKTETTKDL +AL VFNCS+ +DYK G + GLAQ+
Sbjct: 1819 LTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQT 1878
Query: 1518 GAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPG 1577
GAW CFDEFNRI +EVLSVIA Q+ +++A AK F F G I L+ T FITMNPG
Sbjct: 1879 GAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPG 1938
Query: 1578 YAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLS 1637
YAGR ELP+NLKALFRP AM+VP++ LI E++L +EGF +++LARK +Y LC E LS
Sbjct: 1939 YAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS 1998
Query: 1638 QQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIIS 1697
+QDHYD+G+RA+KSVLV+AGSLKR +P ED VL+RAL+D N+PK +TDD +F G+I
Sbjct: 1999 KQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIG 2058
Query: 1698 DLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGG 1757
DLFP + +P + I + LQ E V KV+Q E + VRH V +VG G
Sbjct: 2059 DLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGS 2118
Query: 1758 GKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLM 1817
GK+ V + L +T NL++ + L+PK++T EL+G +N +T EWKDGL
Sbjct: 2119 GKSQVLKSLNKTYQNLKRKPV---------AVDLDPKAVTCDELFGIINPVTREWKDGLF 2169
Query: 1818 ALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLF 1877
+ +R N T + KWII DG +D +WIE++NTV+DDNK+L LA++ERI L + ++F
Sbjct: 2170 STIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVF 2229
Query: 1878 EVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVD 1937
E+ LR A+PATVSR G+++++P +L W P V +W I ++ + + ++ LF +Y+
Sbjct: 2230 EISHLRTATPATVSRAGILYINPADLGWNPVVSSW---IERRKVQSEKANLMILFDKYLP 2286
Query: 1938 EGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCY 1997
L + + P +I+ + T+ LLE L+ K + + FVF
Sbjct: 2287 TCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEK-----TVPPDSPRELYELYFVFTC 2341
Query: 1998 LWSLGGNLTENYYDSFDT-FIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPT 2056
W+ GG + ++ + F + ++ + P+ G ++ ++D DTK+ PW +P+
Sbjct: 2342 FWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPS 2401
Query: 2057 FKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQES 2116
F+ + DVP LV TT+T+R Y M+ L+ V+ G G GKSV+ L + +
Sbjct: 2402 FELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESL-NT 2460
Query: 2117 AGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGS 2176
Y+ + F+ T+SA Q ++E LE+K G PG K++V F+DD+NMP +D+YG+
Sbjct: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520
Query: 2177 QPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLP 2236
P L+RQ+ D +YDR+KL K+I + + AC P G + R RHF + +
Sbjct: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYV-ACMNPTSGSFTIDSRLQRHFCVFAVS 2579
Query: 2237 MPSEHSLKQIFQAILNGFLS--DFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYV 2294
P + +L I+ IL L+ A+++ +S +V A++ ++ K++ LPT K HYV
Sbjct: 2580 FPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYV 2639
Query: 2295 FNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMA 2354
FNLRDLS QG+L ++ + + RL+ HE +RV+ D++++ +D+ H +
Sbjct: 2640 FNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMAST 2699
Query: 2355 NKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNP 2414
K F D E KP I F F D Y + D+ +L D LD YN N
Sbjct: 2700 KKFFDDLGD-ELLFAKPNI---FCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVN- 2754
Query: 2415 KEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELS 2474
+ LV F+DA+ H+ RI R++ RGNALLVGVGG+GKQSL+RLAA+I G QI L
Sbjct: 2755 AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLK 2814
Query: 2475 RGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKD 2534
+GY DL Y A V++ VFL TD+Q+ E+FL IN++L SGE+P LF +D
Sbjct: 2815 KGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMED 2874
Query: 2535 ELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPS 2594
E+E ++++ RP+ K +G+++ R+ +++FI KVR++L ++LC SPVG R R R FP+
Sbjct: 2875 EVENIISSMRPQVKSLGMND-TRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPA 2933
Query: 2595 LVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYN 2654
+VNC IDWF +WP +AL+SVS F + + E+K + VH +V+ M+ Y
Sbjct: 2934 VVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLA 2993
Query: 2655 ELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLS 2714
RR YTTP ++LE I LY ++L++KR ++++ +R++NGL KL T VD +K L+
Sbjct: 2994 TERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3053
Query: 2715 ALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLD 2774
E L K+E + L++ + ++ E + + ++E +V + + DL
Sbjct: 3054 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLA 3113
Query: 2775 EALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISIL------LNAKPDWPSA 2828
+A PAL AA +ALD+L+K +++E++ F PPD V+ V A+ IL + W +A
Sbjct: 3114 KAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAA 3173
Query: 2829 KQLLGD-SNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRA 2887
K ++G FL L ++DKE+I L + Y NP F PE + S A +C W
Sbjct: 3174 KIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCIN 3233
Query: 2888 MDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEK 2947
+ + V V PKRQ L A AEL L + + ++ + L ++K EK
Sbjct: 3234 IVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEK 3293
Query: 2948 ESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYG 3007
+ T ++ A +L L E +RW ES++ F + + G+V + +A V+Y G
Sbjct: 3294 IKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVG 3353
Query: 3008 AFTAQYRQSLIE-CWIQDCQSLEIPIDPSFSL--INILGDPYEIRQWNTDGLPRDLISTE 3064
FT +YR L+E WI +L++PI + L +++L D ++ WN GLP D +STE
Sbjct: 3354 YFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTE 3413
Query: 3065 NGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLL 3124
N ++ RWPL++D Q Q +WI+NK +S LK I+L ++L ++E +I G +L+
Sbjct: 3414 NATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQKSYLDVIEQAISEGDTLLI 3472
Query: 3125 EELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCI 3184
E + ET+DP L+P+L + G I++GD +++Y FR + TK NPHY PE+
Sbjct: 3473 ENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQA 3530
Query: 3185 KVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLF 3244
+ T+INF VT+ GLEDQLL+ VV E+P LE+ + L N K LK +E+ +L L
Sbjct: 3531 QCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLS 3590
Query: 3245 TSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFV 3304
+ GN L + L++ L+ +K T+ I+ ++ EA+ TE IN ARE YRP A + S++YF+
Sbjct: 3591 AASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFI 3650
Query: 3305 IASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFE 3364
+ L++I+P+YQ+SLK F +F I+ + ++QR+ L ++ + Y+ +RGLFE
Sbjct: 3651 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3710
Query: 3365 QHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDL 3424
+ KLI+ + +++ + L+ E +F LR P +L W L
Sbjct: 3711 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKAL 3766
Query: 3425 EESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPW 3484
E F L +I + ++W+ + + +K + ++ W
Sbjct: 3767 SE-MDEFKNLDSDIEG--------------SAKRWKKLVESEAPEKEIFPKE-------W 3804
Query: 3485 SAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVF 3544
++ KL +++C + +++ +A+ +FV E +G +F+E V+ Y++ S +T + F
Sbjct: 3805 K-NKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3863
Query: 3545 ILSTGSDPMGAFQRFARESGY---SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQ-- 3599
ILS G DP+ + ++ G+ + ++ ++SLGQGQ +AE + A + G+WV LQ
Sbjct: 3864 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVR 3923
Query: 3600 ------NCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMP-----SNTFPVTVLQN 3648
N HL W+ +++ ++ ++ + + +R+F+S+ P ++ P +L+N
Sbjct: 3924 GGQHCRNIHLVARWLGTLDKKLEHYS---TGSHEDYRVFISAEPAPSPETHIIPQGILEN 3980
Query: 3649 SVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPL 3708
++K+TNEPP G+ AN+ +A T E +++ ++F +C+FHA++ ER+KFG
Sbjct: 3981 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4040
Query: 3709 GWNICYEFNDSDRECALLNLKLYCKEG-KIPWDALIYITGEITYGGRVTDSWDQRCLRTI 3767
GWN Y FN+ D ++ L Y + K+PWD L Y+ GEI YGG +TD WD+R RT
Sbjct: 4041 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTY 4100
Query: 3768 LKRFFSPETLEEDYKYSESGIYFAPMADSLQEFKDYI-ENLPLIDDPEIFGMHENANLVF 3826
L + E LE D + G P D + + +YI ENLP + P ++G+H NA + F
Sbjct: 4101 LAEYIRTEMLEGDVLLA-PGFQIPPNLD-YKGYHEYIDENLP-PESPYLYGLHPNAEIGF 4157
Query: 3827 QYKETSTLINTILEVQPR--SSTGGEGKSNDEIVQELVASVQTRVPEKLE---------- 3874
+ L T+LE+QP+ S G G S +E L R E LE
Sbjct: 4158 LTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTG 4217
Query: 3875 ----------MEGASESLFVKDLQGRLNSLT---TVLGQEVDRFNNLLKLIHTSLETLNK 3921
+E E+ + ++ + T V QE +R N L + SL+ LN
Sbjct: 4218 FQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNL 4277
Query: 3922 AIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKR- 3980
+ G + ++ ++E + + + VP W AYPS+ L +W DL+LR ++ W
Sbjct: 4278 GLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDF 4337
Query: 3981 GQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQ 4040
P + W++GFF PQ FLT +Q+ ARK P+D++ V R+
Sbjct: 4338 ALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNRE------------ 4385
Query: 4041 FGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEP-QQN 4099
DM P P +G V+G+FM+ +RWD + VI +A ++ P +PV+ + +
Sbjct: 4386 -------DMTAP-PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVD 4437
Query: 4100 YKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQL 4156
+ +Y CP+YKT R T +V T L +K WI ALL Q+
Sbjct: 4438 RMETKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 1964 bits (5088), Expect = 0.0
Identities = 1193/3731 (31%), Positives = 1984/3731 (53%), Gaps = 191/3731 (5%)
Query: 503 QEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGI-----------LGAVNHCQNTVLSV 551
+++ E +I +E+ L + +++ PSL+D I G + Q + +
Sbjct: 873 RKQSEDIISFIKSEVHLAIPNVVMIPSLDDIQQAINRMIQLTLEVSRGVAHWGQQQIRPI 932
Query: 552 PNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQIKE--------- 602
+++P T L+ + ++ A KNF+ +++ K+
Sbjct: 933 KSVIPSPTTTDVTHQNTGKLLKKEERSFEEAIPA--RKLKNFYPGVAEHKDISKLVLLLS 990
Query: 603 -TIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAV 661
++ + ++A F+K++ + E+ + ++ P + ++ Y ++
Sbjct: 991 SSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILHYATFEQEID 1050
Query: 662 ALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLE 721
L+P VG L + T ++ L +L L + KKK+ +I + KL
Sbjct: 1051 ELKPIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEYLKKLS 1110
Query: 722 FVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMKP 781
+ ++ L I++ ++ + + Y ++ +++V E+ T++
Sbjct: 1111 RPIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRY 1170
Query: 782 SIVAVRNAIDKSVGDRESSIK---QFCVHLGSDLEELNNEVNEVK--LQAQDPQILDISA 836
S +++ K+V +E ++ +F +L +E +V + + P + +I
Sbjct: 1171 SFNKLQS---KAVSVQEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNIPP 1227
Query: 837 DQDKIRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSF 896
+ RL + Q+ DL ++ Y S ++ F + V+ +E L + EL L Q L+ +
Sbjct: 1228 QEASNRLQI--FQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLY 1285
Query: 897 SEWDKLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEK 956
+ + + +D E +N ++ ++ +L KGL LK +++ E
Sbjct: 1286 DTVMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSES 1345
Query: 957 LPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQAS 1016
P++ + N +K RHW I + L + + + +I+DI A
Sbjct: 1346 CPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAI 1405
Query: 1017 GEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTD--DIQVLLDDSTINVATLASS 1074
E +EA L +V ++W T + + K +L GT+ +I L++DS + + +L S+
Sbjct: 1406 KEKDIEAKLTQVIENW-TNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSN 1464
Query: 1075 RYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQV 1134
RY P K + W +L+ + +EEWL Q W+YLE++F DI +QLP EAK F +
Sbjct: 1465 RYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNI 1524
Query: 1135 DKSWKEIMRKVNRLPNALRAATQPGLL-ETFQNNNALLDQIQKCLEAYLESKRVIFPRFY 1193
DKSW +IM++ + PN + + + + + L+ QK L YLE KR++FPRF+
Sbjct: 1525 DKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFF 1584
Query: 1194 FLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTND 1253
F+S+ LLEIL Q + +QPHL D+I+++ F K Y
Sbjct: 1585 FVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHA----------------KDYDR- 1627
Query: 1254 ILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAA---IADYQGKLRTD 1310
I+A++S EGE++ L + A+G VE WL + + +SL + ++A I+D +L
Sbjct: 1628 IMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLP- 1686
Query: 1311 WVVAGHPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSL 1370
++ P+QV L Q++W D E L + + ++ + + LN L + L
Sbjct: 1687 -FLSHFPAQVGLLGIQMLWTHDSEEALRNAKDDR-KIMQVTNQKFLDILNTLISQTTHDL 1744
Query: 1371 PKLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALS 1430
K R LITI VH RDI +LV+ +++ F+W +Q R+Y+ DLD V +
Sbjct: 1745 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 1804
Query: 1431 QYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALA 1490
+ Y E+LG RLVITPLTDRCY+ L AL +++GGAPAGPAGTGKTETTKD+ + L
Sbjct: 1805 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 1864
Query: 1491 IQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAA 1550
VVFNCSD +D++ +GR F GLAQSG+W CFDEFNRI++ VLSV AQQ+ + A+
Sbjct: 1865 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 1924
Query: 1551 KLSRFMF-EGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVI 1609
+ +F+F +G + L F+TMNPGYAGR ELP+NLK FR AMMVP+ +I V
Sbjct: 1925 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 1984
Query: 1610 LYSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNED 1669
L S GF + ILA+K +YKLC EQL++Q HYDFG+R + SVL GS KR P+ +E
Sbjct: 1985 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044
Query: 1670 VVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPE 1729
+++R L+D NL K + +D LF +I+DLFPG+Q+ + Y LQ+ + + + L
Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2104
Query: 1730 MCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTY 1789
K++Q YET LVRHG+M +GP+G GKTTV IL + + + +
Sbjct: 2105 PPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKA---------QTECGRPHREM 2155
Query: 1790 VLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENM 1849
+NPK+IT +++G ++ T +W DG+ + R + ++ ++I DGPVDA+WIEN+
Sbjct: 2156 RMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENL 2215
Query: 1850 NTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYV 1909
N+VLDDNK L LAN +RI + P +LFEV ++ ASPATVSR GMV++ L W P +
Sbjct: 2216 NSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPIL 2275
Query: 1910 KTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESL 1969
+ W+K K T + L L+++ ++ ++ + + ++ + + LLE L
Sbjct: 2276 QAWLK----KRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGL 2331
Query: 1970 ILGKD--GVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFD--DNP 2025
I K+ GV+ KL FVF +WSLG L + + F+R D P
Sbjct: 2332 IPSKEEGGVSCVEHLHKL-------FVFGLMWSLGALLELESREKLEAFLRQHESKLDLP 2384
Query: 2026 DARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRD-VP-FFEMLVPTTDTVRYGYLME 2083
+ ++ ++ ++ D + W + + + Y D +P + +LVP D +R +L++
Sbjct: 2385 EIPKGSNQTMYEFYVT-DYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLID 2443
Query: 2084 KLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKL 2143
+ +VL TG G K+V+ K L K + LNFS+ T Q IES +
Sbjct: 2444 TIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEV-QLSKSLNFSSATEPMMFQRTIESYV 2502
Query: 2144 ERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLF-WKE 2202
+++ + G PG +++ +F+DD+NMP ++ +G Q E++RQ + G Y +K +
Sbjct: 2503 DKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTT 2562
Query: 2203 IQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLS---DFP 2259
I DV +I+A PGGGRN + R R F++ +PS S+ +IF I G+ F
Sbjct: 2563 IVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFK 2622
Query: 2260 PAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEI 2319
P + + ++V ++ V +LPTP+K HY+FNLRDLS+ QG+L
Sbjct: 2623 PQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIP 2682
Query: 2320 QIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFG-----IAIDLEYFLN----K 2370
+ LF HEC RV DR I ED+ +F+ LT ++ G + YF++
Sbjct: 2683 TLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREM 2742
Query: 2371 PIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYN-LTNPKEVKLVFFQDAIEHV 2429
P GD + + +IY+ MP + A LQ Y +N + + LVFF+DA+ H+
Sbjct: 2743 PEPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHL 2802
Query: 2430 SRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKL 2489
+I+R+IR GNALLVGVGG+GKQSL+RLA+ I GY+ QI L+R YN + +DL+ L
Sbjct: 2803 IKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKAL 2862
Query: 2490 YKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAK- 2548
YK+AG + K + F+FTD++I E FLE +NN+L+SGE+ NLF +DE++++ K
Sbjct: 2863 YKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKR 2922
Query: 2549 EVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWP 2608
E+ D +++YFIS+ R+ LH+VLC SPVGE FR+R FP L++ CT+DWF +WP
Sbjct: 2923 ELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWP 2982
Query: 2609 REALLSVSKTFFSQVD-AGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTSY 2667
REAL++V+ F S + + E+K ++ H VS E Y+ RRR + TP SY
Sbjct: 2983 REALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSY 3042
Query: 2668 LELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDV 2727
L IN Y ++ +EK K I +R+ GL KL+E + V K+ DL+ E L S
Sbjct: 3043 LSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKA 3102
Query: 2728 EALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKAL 2787
+ ++ ++ V +++ +++N VQE + A+ +E + A+ L+ A PAL+ A AL
Sbjct: 3103 DEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAAL 3162
Query: 2788 DSLDKADISEIRVFTKPPDLVMTVMEAISILLN--------------AKPDWPSAKQLLG 2833
+++ DI+ +R KPP L+M +M+ + +L KP W + +L+
Sbjct: 3163 NTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMS 3222
Query: 2834 DSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSR 2893
+ FL L ++ K+ I + + LQ Y N D+ E +KV + W AM ++
Sbjct: 3223 ATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYG 3282
Query: 2894 VVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKT 2953
+ + V P + L + L + A L + QALL + + ++ +Q ++D +NEK L
Sbjct: 3283 INREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLND 3342
Query: 2954 MALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQY 3013
+ ++ A L L E++RW + ++F+ +I+ + G++ + ++Y G F +
Sbjct: 3343 ADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIF 3402
Query: 3014 RQSLI-ECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQG 3072
R L+ + W + ++ +IP + +LI++L DP I +W GLP D +S +NGI+VT+
Sbjct: 3403 RNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKA 3462
Query: 3073 RRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLD 3132
R+PL+IDPQ Q WI++KE ++ L++ L F LE+S+ LG P+L+E++ E LD
Sbjct: 3463 TRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELD 3522
Query: 3133 PALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFT 3192
PAL+ +L K SG +++GD + D F+ Y+TTK+PNP + PE+ K ++I+FT
Sbjct: 3523 PALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFT 3582
Query: 3193 VTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILD 3252
VT GLE+QLL V+ EK LE +R+KL+ + +K ++K +E+ +L L ++G+++D
Sbjct: 3583 VTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVD 3642
Query: 3253 NEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEID 3312
+E LI L+ +K T+ + +L A TE IN A+E++RP AT+GS++YF+I +S ++
Sbjct: 3643 DESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVN 3702
Query: 3313 PMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSF 3372
MYQ SL F +LF+ ++ S K+ Q+R+ ++E + RGL+E HK ++
Sbjct: 3703 IMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVL 3762
Query: 3373 MLCVEMMRQQGTLSDAEWNFFLRGSAGLE-KERPPKPEAPWLPTATWFACCDLEESFPVF 3431
++ +++ Q+GT+ E+ ++G A L+ K PPKP W+ TW +L + P F
Sbjct: 3763 LMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPYR-WILDMTWLNLVELSK-LPQF 3820
Query: 3432 HGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSF 3491
+ I N + W+ + DK +E+ D ++ L +
Sbjct: 3821 AEIMNQISR--------------NEKGWKSWF-----DKDAPEEE--IIPDGYNDSLDTC 3859
Query: 3492 HKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILSTGSD 3551
HKL+LI+ ++ VF ++ ++L +++ E ++L +++ TPL+ LS GSD
Sbjct: 3860 HKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSD 3919
Query: 3552 PMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAM 3611
P A++ ++IS+GQGQ A K+++ +M+ G WV LQNCHL + + M
Sbjct: 3920 PTNQIDALAKK--LKLECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEF---M 3974
Query: 3612 EELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEM 3671
EEL++T + A D+FR+++++ P + FP+T+LQ S+K TNEPP+G+RA ++R F +
Sbjct: 3975 EELLETLITTE-ASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGI 4033
Query: 3672 TPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLY 3731
+ + L W+ +++ + F H+ +QER+KFGPLGWNI YEFN +D ++ ++ +
Sbjct: 4034 NQDLLDISNL-PMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNH 4092
Query: 3732 CKEGKI----PWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESG 3787
E I W+ + Y+ GE+ YGGRVTD +D+R L + +FS + E + +
Sbjct: 4093 LDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTG- 4151
Query: 3788 IYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSST 3847
Y P+ +L ++ +YI++LP +D+PE+FG+H NA++ +Q S ++ TI +QP+ S
Sbjct: 4152 -YKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITNIQPKESG 4210
Query: 3848 GGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNN 3907
GG G++ + IV L + +++P + +S +K G LNS+ L QE+DR
Sbjct: 4211 GGVGETREAIVYRLSEDMLSKLPPDY-IPHEVKSRLIK--MGHLNSMNIFLRQEIDRMQR 4267
Query: 3908 LLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDL 3967
++ ++ +SL L AI G ++MSE + ++ + ++P LW ++ S LG W +L
Sbjct: 4268 VISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVSWDS-STLGFWFTEL 4326
Query: 3968 ILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKY-NLPIDELSFKYSVIPTY 4026
+ R + W+ G+P +W++GFF PQGFLT Q R + +D ++ V+
Sbjct: 4327 LERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQT 4386
Query: 4027 RDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMN 4086
+++ P +GV ++G++MD + WD + + ++ P +
Sbjct: 4387 KEEIT--------------------SPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLF 4426
Query: 4087 PVLPVVH-FEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYW 4145
LPV+H F P LY CP+YK R F+ V L + S D+W
Sbjct: 4427 TQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRT--------DLTFITVVYLRTVLSPDHW 4478
Query: 4146 IAKGSALLCQL 4156
I +G ALLC +
Sbjct: 4479 ILRGVALLCDI 4489
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 1892 bits (4902), Expect = 0.0
Identities = 1167/3742 (31%), Positives = 1938/3742 (51%), Gaps = 214/3742 (5%)
Query: 507 ESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSP 566
++ +P+F + L + +++ P+LED + +N ++SVP V + +
Sbjct: 1004 QNSLPIFRASVTLAIPNIVMAPALED----VQQTLNKAVECIISVPKGVRQWSSELLSKK 1059
Query: 567 YINNKLEGKTCGTGPSLAAVFEDD--------------------KNFHTIISQIKETIQA 606
I + S + V + KN++ +S+ KE ++
Sbjct: 1060 KIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKL 1119
Query: 607 AFESARIYAAT----------FEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQ 656
+ I +T F+++ +++ + ++ Q P ++ F Q+ +
Sbjct: 1120 VSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNL 1179
Query: 657 HKDAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDA 716
++ A VG + + T L+ L + V+ ++ + +++ I ++
Sbjct: 1180 EQEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEF 1239
Query: 717 EYKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVF 776
KL + ++ L EI+E S++ + + + Y L+ +Y + E+
Sbjct: 1240 NKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299
Query: 777 ATMK---PSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQ--AQDPQI 831
T+ ++A + + + S K+ L S +E + ++ L P
Sbjct: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKK---ELISAVEVFLQDCHQFYLDYDLNGPMA 1356
Query: 832 LDISADQDKIRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQL 891
+ + RLI+ Q+ ++ ++ Y ++ F + +++ L E+ +L L Q
Sbjct: 1357 SGLKPQEASDRLIM--FQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQK 1414
Query: 892 LWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVE 951
++ ++ + + + ++ E +N ++ ++ +L + L LK ++
Sbjct: 1415 IYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIID 1474
Query: 952 KMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDI 1011
E P++ + + + RHW I +L L + + + + +EI+DI
Sbjct: 1475 DFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDI 1534
Query: 1012 SGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILG-GTDDIQVLLDDSTINVAT 1070
A E +E LK+V + W F + ++ + G T +I ++DS + + +
Sbjct: 1535 CISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGS 1594
Query: 1071 LASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKM 1130
L S+RY P K ++ +W + L+ +E W+T Q W+YLE++F DI +QLP EAK
Sbjct: 1595 LLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKR 1654
Query: 1131 FLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQI---QKCLEAYLESKRV 1187
F +DKSW +IM + + +P+ ++ L + LLDQ+ QK L YLE KR+
Sbjct: 1655 FSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPH--LLDQLEICQKSLTGYLEKKRL 1712
Query: 1188 IFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPE 1247
FPRF+F+S+ LLEIL Q + +Q HL FD+I ++F E
Sbjct: 1713 CFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFH----------------E 1756
Query: 1248 KVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQ--G 1305
K+Y IL++ S EGE + L K + A GNVE WL + E +SL + + A A+ Q G
Sbjct: 1757 KIYDR-ILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETG 1815
Query: 1306 KLRTDWVVAGHPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAI 1365
T+++ + P+QV L Q++W RD E L + + ++ + E LN L +
Sbjct: 1816 FQLTEFL-SSFPAQVGLLGIQMIWTRDSEEALRNAKFDK-KIMQKTNQAFLELLNTLIDV 1873
Query: 1366 VQGSLPKLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVA 1425
L R LITI VH RDI +L +++ F+W +Q R+Y++ D D +
Sbjct: 1874 TTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMI 1933
Query: 1426 RMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDL 1485
+ + Y E+LG RLVITPLTDRCY+ L AL + +GGAPAGPAGTGKTETTKD+
Sbjct: 1934 HITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDM 1993
Query: 1486 AKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIR 1545
+ L VVFNCSD +D++ +GR F GLAQSG+W CFDEFNRID+ VLSV AQQ+ I
Sbjct: 1994 GRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIIL 2053
Query: 1546 NAKAAKLSRFMF-EGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYAL 1604
K F+F +G + + F+TMNPGYAGR ELP+NLK FR AMMVP+ +
Sbjct: 2054 TCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQI 2113
Query: 1605 IAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENP 1664
I V L S GF + +LARK +YKLC EQLS+Q HYDFG+R + SVL G+ KR NP
Sbjct: 2114 IIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANP 2173
Query: 1665 DLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQ 1724
E +++R L+D NL K + +D LF +I DLFP + + + Y L++ I +
Sbjct: 2174 MDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEA 2233
Query: 1725 NLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQ 1784
L KVIQ +ET VRHG+M +GP+G GKTT L + + K E
Sbjct: 2234 GLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMR--- 2290
Query: 1785 AVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDAL 1844
+NPK+IT +++G ++ T +W DG+ + R + +H WII DGPVDA+
Sbjct: 2291 ------MNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAI 2344
Query: 1845 WIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELK 1904
WIEN+N+VLDDNK L LAN +RI + P ++FE ++ ASPATVSR GMVF+ L
Sbjct: 2345 WIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILD 2404
Query: 1905 WMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCC 1964
W P ++G KK + + E + L+ + F + + ++ +T
Sbjct: 2405 WSPI----LEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSIN 2460
Query: 1965 LLESLI-LGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDD 2023
+L+ LI L + G ++ L + FVF LWS G L + + ++R++
Sbjct: 2461 MLQGLIPLKEQGGEVSQAH------LGRLFVFALLWSAGAALELDGRRRLELWLRSRPTG 2514
Query: 2024 NPDARLP-NSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVP--FFEMLVPTTDTVRYGY 2080
+ P GD + W + Y D + +LVP D VR +
Sbjct: 2515 TLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDF 2574
Query: 2081 LMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIE 2140
L++ + +VL G G K+VI KG ++K + LNFS+ T+ Q IE
Sbjct: 2575 LIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKS-LNFSSATTPLMFQRTIE 2633
Query: 2141 SKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLF- 2199
S ++++ G P K++ +F+DD+NMP ++ +G Q E++RQ + GFY+ K
Sbjct: 2634 SYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGE 2693
Query: 2200 WKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSD-- 2257
+ I D+ ++A PGGGRN + R R FS+ +PSE S+ +IF I G
Sbjct: 2694 FTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQR 2753
Query: 2258 -FPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIR 2316
F V+ + + +V + ++ + +LPTPAK HYVFNLRDLS+ QG+L I+
Sbjct: 2754 GFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIK 2813
Query: 2317 EEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFG----IAID-------LE 2365
E + +L+ HEC+RV DR + D +F L + + FG + +D ++
Sbjct: 2814 EPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVD 2873
Query: 2366 YFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLT-NPKEVKLVFFQD 2424
+ + P G+ + + +IY+ + L +L YN + + +VFF D
Sbjct: 2874 FLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFAD 2933
Query: 2425 AIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHE 2484
A+ H+ +I+R+IR +GNALLVGVGG+GKQSLTRLA+ I GY QI L+R YN + E
Sbjct: 2934 AMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLME 2993
Query: 2485 DLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLA-AT 2543
DL+ LY+ AG + K + F+FTD +I E FLE +NN+L+SGEV NLF +DE++++ +
Sbjct: 2994 DLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLA 3053
Query: 2544 RPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDW 2603
KE + + YF+S+VRQ LHIVLC SPVGE FR+R FP+L++ CTIDW
Sbjct: 3054 SVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDW 3113
Query: 2604 FVQWPREALLSVSKTFFSQVDAG-NEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYT 2662
F +WP++AL++VS+ F + D + E+K+++ + V+ Y+ RR +
Sbjct: 3114 FSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHV 3173
Query: 2663 TPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLA 2722
TP SYL I Y + EK ++ + +R+ GL KL E + V + +L A E L
Sbjct: 3174 TPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQV 3233
Query: 2723 KSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRD-------LDE 2775
++ + +++++ + ++A++V+ VQ KVK + QAI D +D L+
Sbjct: 3234 ANDKADMVLKEVTMKAQAAEKVKAEVQ------KVK-DRAQAIVDSISKDKAIAEEKLEA 3286
Query: 2776 ALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAK------------- 2822
A PAL+ A AL ++ +DI+ +R +PP L+M +M+ + +L K
Sbjct: 3287 AKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCT 3346
Query: 2823 -PDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSM 2881
P W + +L+ NFL+ L ++ K+ I +++ L Y PD+ E ++V +
Sbjct: 3347 MPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGL 3406
Query: 2882 CMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYD 2941
C W +AM + + K V P + L + + M L++ QA L + ++ +Q EY+
Sbjct: 3407 CSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYE 3466
Query: 2942 KGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAA 3001
+ + EK++L + + ++ A L + L E+ RW E Q+F + + G+V +A A
Sbjct: 3467 QAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATA 3526
Query: 3002 CVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLI 3061
++Y G F ++R L+ W ++ ++ +IP + +L +L D I +WN GLP D +
Sbjct: 3527 FLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDL 3586
Query: 3062 STENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLP 3121
S +NGI+VT+ R+PL+IDPQ Q WI+NKES++ L+I L F LE+S+ LG P
Sbjct: 3587 SIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRP 3646
Query: 3122 VLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPE 3181
+L+E++ E LDPAL+ +L + +G +++GD ++D FR Y+TTK+PNP Y PE
Sbjct: 3647 LLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPE 3706
Query: 3182 VCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILR 3241
+ + +II+FTVT GLEDQLL V+ EK LE++R L+ + +K ++K +E+ +L
Sbjct: 3707 ISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLY 3766
Query: 3242 MLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVM 3301
L +++G+++++E LI L ++K T+ + +LE + TE IN ARE+YRPVAT+GS++
Sbjct: 3767 RLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSIL 3826
Query: 3302 YFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRG 3361
YF+I + ++ MYQ SL+ F LF+ ++ SVK+ +R+ ++E Y +RG
Sbjct: 3827 YFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARG 3886
Query: 3362 LFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLE-KERPPKPEAPWLPTATWFA 3420
L+E+HK +++ +L +++ Q+ + E+ ++G A L+ K PPKP + W+ TW
Sbjct: 3887 LYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKP-SKWILDITWLN 3945
Query: 3421 CCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAH 3480
+L + F + I N + W+ + DK +E+
Sbjct: 3946 LVELSK-LRQFSDVLDQISR--------------NEKMWKIWF-----DKENPEEEPL-- 3983
Query: 3481 QDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNT 3540
+ + L F +L+LI+ ++ + ++++++G+++ E +DL +++ T
Sbjct: 3984 PNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRT 4043
Query: 3541 PLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN 3600
PL+ +LS GSDP + + R +S+GQGQ A K+++ M +G W LQN
Sbjct: 4044 PLICLLSMGSDPTDSIIALGKRLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALLQN 4101
Query: 3601 CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL 3660
CHL + + M+EL+ + + + D FRL++++ FP+T+LQ S+K N+PP+GL
Sbjct: 4102 CHLGLDF---MDELMDIIIETE-LVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGL 4157
Query: 3661 RANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSD 3720
RA ++R ++ ++ + + G +W+ +++ + F H+ +QER+KFG LGWNI YEFN +D
Sbjct: 4158 RAGLKRTYSGVSQDLLDVS-SGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQAD 4216
Query: 3721 RECALLNLK-----LYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPE 3775
+ ++ + K+G + W + Y+ GEI YGGRVTD +D+R L T K +FS
Sbjct: 4217 FNATVQFIQNHLDDMDVKKG-VSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSEN 4275
Query: 3776 TLEEDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLI 3835
D+ + + Y P ++ + YI++LP D PE+FG+H NA++ +Q K ++
Sbjct: 4276 MFGPDFSFYQG--YNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVL 4333
Query: 3836 NTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLT 3895
+TIL +QP+ ++GG ++ + +V L + ++P E L G +
Sbjct: 4334 DTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERL---QKMGPFQPMN 4390
Query: 3896 TVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYP 3955
L QE+DR +L L+ ++L L AI G ++MSE + + + ++PA W ++
Sbjct: 4391 IFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWI 4450
Query: 3956 SLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHAR-KYNLPID 4014
S LG W +LI R S W+ G+P +W++GFF PQGFLT Q R +D
Sbjct: 4451 S-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALD 4509
Query: 4015 ELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKE 4074
+ V +D D+ P P +GV V+G++++ + WD +
Sbjct: 4510 NMVLCNEVTKWMKD-------------------DISAP-PTEGVYVYGLYLEGAGWDKRN 4549
Query: 4075 MVIEDALPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTV 4134
M + ++ P + ++PV+ + N P Y CP+YK R N++ V
Sbjct: 4550 MKLIESKPKVLFELMPVIRIYAENNTLRDPRFYSCPIYKKPVRT--------DLNYIAAV 4601
Query: 4135 LLPSKRSKDYWIAKGSALLCQL 4156
L + ++ ++W+ +G ALLC +
Sbjct: 4602 DLRTAQTPEHWVLRGVALLCDV 4623
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1397 bits (3616), Expect = 0.0
Identities = 1014/3626 (27%), Positives = 1770/3626 (48%), Gaps = 340/3626 (9%)
Query: 726 TTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMKPSIVA 785
+T++ V + ++ ++ +I+ E + + +L+E+ + PP + +I
Sbjct: 1162 STSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYI-----DNIEG 1216
Query: 786 VRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLIL 845
A + + ++S+I+Q +L + + + V + + D+ D +K + +
Sbjct: 1217 EWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAV--------ESRTTDLLTDWEKTKPVT 1268
Query: 846 NNLQSVLADLQKRAFQYKSYQ-KNFKVEVSKF-EALE----------EVSAELKLKQL-- 891
NL+ A ++ K + K+ + + +K EALE E ++ L++L
Sbjct: 1269 GNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQD 1328
Query: 892 ---LWDSFSE-WDKL----QQEW-------LKSKFDCLDPEVLN--GQVSKYA--KFVTQ 932
+W S+ W+++ +Q W L+ D L ++ + ++ +YA +FV +
Sbjct: 1329 LKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQR 1388
Query: 933 LEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLT 992
L KG MK + ++I+L++ LK RHW + + + V +E LT
Sbjct: 1389 LLKGY---------------MKINM-LVIELKSEALKDRHWKQLMKRLHVNWVVSE--LT 1430
Query: 993 LERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILG 1052
L ++ + + ++D+ A GE ALE LK++ + W T E ++ +++ ++
Sbjct: 1431 LGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNK--CRLIR 1488
Query: 1053 GTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLE 1112
G DD+ + + +V+ + S Y + W+ +L + W+ QR W+YLE
Sbjct: 1489 GWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLE 1548
Query: 1113 SIFN-APDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALL 1171
IF + DI+ LP E + F + + +M+KV++ P + G+ + + LL
Sbjct: 1549 GIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLL 1608
Query: 1172 DQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFAL 1231
+IQK L YLE +R FPRFYF+ +++LLEI+ ++N +Q H +K F +S +
Sbjct: 1609 GKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSI---- 1664
Query: 1232 MPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGK--GLKARGNVEEWLGKVEEAMF 1289
I E V +L + S EGE V + + EWL VE+ M
Sbjct: 1665 ----------ILNEDNSV----VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMR 1710
Query: 1290 TSLRRLCKAAIADYQ--GKLRT-------DWVVAGHPSQVILTVSQIMWCRDLTECLETE 1340
+L +L ++ + + GK + W+ + +Q+++ +QI W ++ L +
Sbjct: 1711 VTLAKLLAESVTEVEIFGKATSIDPNTYITWIDK-YQAQLVVLSAQIAWSENVETALSSM 1769
Query: 1341 HSNHIQALKNFEKVNFE-RLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSK 1399
A + N E LN LA V P L R L LIT VH RD+ L++SK
Sbjct: 1770 GGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSK 1829
Query: 1400 VETVESFDWQRQLRYYWDID----LDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCY 1455
++ +SF+W Q+R+Y+D L +MA +++ YG+EYLG +LV TPLTDRCY
Sbjct: 1830 IDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCY 1889
Query: 1456 LCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLA 1515
L + AL+ LGG+P GPAGTGKTE+ K L L +VFNC + D++ MGR F GL
Sbjct: 1890 LTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLC 1949
Query: 1516 QSGAWCCFDEFNRIDIEVLSVIAQQLITIRNA----------KAAKLSRFMFEGREIKLV 1565
Q GAW CFDEFNR++ +LS ++QQ+ I+ A K + +++K+
Sbjct: 1950 QVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVS 2009
Query: 1566 MTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKM 1625
A FITMNPGYAGR+ LPDNLK LFR AM P+ LIA+V+LYS+GF ++++LA K+
Sbjct: 2010 PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKI 2069
Query: 1626 TQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKREN---------------------P 1664
+KLC EQLS Q HYDFG+RA+KSVLV AG++KRE
Sbjct: 2070 VPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAE 2129
Query: 1665 DLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQ 1724
+L E +LI+++ ++ +PK + +D L ++SD+FPGVQ + L+ + V
Sbjct: 2130 NLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEM 2189
Query: 1725 NL------QPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGI 1778
L + V KV+Q Y+ + HG+M+VGP+G GK+ +R+L + L L+ G+
Sbjct: 2190 YLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLE--GV 2247
Query: 1779 ENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTS---EDHKWI 1835
E ++++PK+I+ LYG ++ T EW DGL +R ++ + +WI
Sbjct: 2248 EGV------AHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWI 2301
Query: 1836 ISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGM 1895
+ DG VD W+EN+N+VLDDNK+L L N ER+ L P + ++FEVQDL+ A+ ATVSRCGM
Sbjct: 2302 VFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGM 2361
Query: 1896 VFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLH-------------- 1941
V+ + L ++ + +E ++ + DEG
Sbjct: 2362 VWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAAT 2421
Query: 1942 ----------FINKKCSQAIPQVDISKVTTLCCL--LESLI---------LGKDGVNLAM 1980
+ K A I +T L CL L S++ + + M
Sbjct: 2422 IMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPM 2481
Query: 1981 EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHM 2040
+ +L + + V+ LWSL G+ +IR LP + ++ I
Sbjct: 2482 QIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRI----TTVPLPTAPNIPIIDY 2537
Query: 2041 DFDTK-RLDPWERIIPTFKYN-RDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGIT 2098
+ PW+ +P + V +++VPT DTVR+ L+ LA ++ G
Sbjct: 2538 EVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPP 2597
Query: 2099 GVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKR--KNILGAPGN 2156
G GK++ L + + V LNFS+ T+ + + E +R ++ AP
Sbjct: 2598 GSGKTMTLFSALRALPDME---VVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQ 2654
Query: 2157 --KRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAP 2214
K +V+F D++N+P +D+YG+Q I +RQ + GGFY + W +++ + + AC P
Sbjct: 2655 LGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNP 2714
Query: 2215 PGG-GRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEAS 2273
P GR P++ RF+RH ++ + P SL QI+ N + P+++ A + A
Sbjct: 2715 PTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIY-GTFNRAMLRLIPSLRTYAEPLTAAM 2773
Query: 2274 VEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQC-DPGTIREEIQIFRLFCHECQRV 2332
VE Y MS + + HY+++ R++++ V+GI + P + R++ HE R+
Sbjct: 2774 VEFYT-MSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRL 2832
Query: 2333 FHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDM 2392
F DRL+ +E++ + + +A KHF ID E +++PI++ +++ D+ +++
Sbjct: 2833 FQDRLVEDEERRWTDENIDTVALKHFP-NIDREKAMSRPILYSNWLSKDYIPVDQ--EEL 2889
Query: 2393 PDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTG 2452
D K A + Y ++ +V LV F + ++HV RI R+ RQ +G+ LL+GV G G
Sbjct: 2890 RDYVK-ARLKVFYEEEL------DVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAG 2942
Query: 2453 KQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVE 2512
K +L+R A + G QI++ R Y + F EDLR + + +G +++ + F+ ++ ++
Sbjct: 2943 KTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDS 3002
Query: 2513 EFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKL 2572
FLE +N +L +GEVP LFE DE ++ + A++ G+ + +E++++F S+V + L
Sbjct: 3003 GFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNL 3062
Query: 2573 HIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEE--- 2629
H+V M+P E + R P+L N C ++WF W EAL V K F S++D
Sbjct: 3063 HVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIV 3122
Query: 2630 ------LKEKLPL----------MCVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINL 2673
+ +KLP CV VH ++ R R TP YL+ IN
Sbjct: 3123 PDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINH 3182
Query: 2674 YLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEK 2733
Y ++ EKR ++ + + GL K+ ET V++++ DL L K+ ++K
Sbjct: 3183 YANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKK 3242
Query: 2734 LAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKALDSLDKA 2793
+ DQ+ A++ + QE + + E + DLD+ PA+ A A+ S+ K
Sbjct: 3243 MVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQ 3302
Query: 2794 DISEIRVFTKPPDLVMTVMEAISILL-NAKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQ 2852
+ E+R PP V +E+I +LL + DW + ++ NF+ ++ + E I
Sbjct: 3303 HLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDA 3362
Query: 2853 ILAKLQK-YINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAE 2911
I K++K Y++NP + E V + S AC M W A Y+ ++K VEP R +L+ + +
Sbjct: 3363 IREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDD 3422
Query: 2912 LDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAAL 2971
E + ++R +E I ++EY ++E +++ +A +A++ R+ L +L
Sbjct: 3423 AKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSL 3482
Query: 2972 EDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIP 3031
E+ RWE++ + F+ ++S I G+ ++AA +AY G F Q RQ+L W Q I
Sbjct: 3483 SAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQ 3542
Query: 3032 IDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRN 3091
+ L + E +W LP D + TEN I++ + R+PL+IDP QA +I N
Sbjct: 3543 FRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMN 3602
Query: 3092 KESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLL 3151
+ + D F + LE+++R G P+L++++ E+ DP L P+L +++ +GGR+L
Sbjct: 3603 EYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVL 3661
Query: 3152 IRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEK 3211
I LGD DID +F +++T+ P + P++C +VT +NFTVT+S L+ Q L++V++ E+
Sbjct: 3662 ITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAER 3721
Query: 3212 PRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIK 3271
P ++E+R L+ + +L+ +E+ +L+ L +G ILD++ +I TL++ K + +
Sbjct: 3722 PDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVT 3781
Query: 3272 TRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIE 3331
++EE + Q + ++Y P++T S +YF + SL +I +YQYSL++F +++ +
Sbjct: 3782 RKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLY 3841
Query: 3332 TSVKTENL---QQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLS-- 3386
+ + + QRL ++ + A+ V+RG+ Q + ++ +L ++ +GT+
Sbjct: 3842 ENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLA--RIKLKGTVGEP 3899
Query: 3387 --DAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPVFHGLTQNILSHPIS 3444
DAE+ FLRG+ + P L A L P F L + +
Sbjct: 3900 TYDAEFQHFLRGNE-IVLSAGSTPRIQGLTVEQAEAVVRL-SCLPAFKDLIAKVQADE-- 3955
Query: 3445 IRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEK 3504
+ G + +P++ Y + + P + + H+L+LI+ + ++
Sbjct: 3956 -QFGIWLDSSSPEQTVPYL--------------WSEETPATPIGQAIHRLLLIQAFRPDR 4000
Query: 3505 VVFALTDFVIENLGKQF--IETPPVDLPTLY-QDMSCNTPLVFILSTGSDPMGAFQRFAR 3561
++ FV NLG+ F I P+DL + ++ NTP++ G D G + A
Sbjct: 4001 LLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAA 4060
Query: 3562 ESGYSERVQSISLGQGQG-PIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTD 3620
E + ++ SI++G +G A+K + A+KSG WV L+N HLA W++ +E+ + +
Sbjct: 4061 EQ--NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSL-Q 4117
Query: 3621 PDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFFEENI 3680
P + FRLFL+ + PV +L+ EPP G++AN+ R F+ + S ++
Sbjct: 4118 PHAC----FRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKS- 4172
Query: 3681 LGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKE------ 3734
+ ++ F + +FHAIIQER ++ PLGW+ YEF +SD A + + +
Sbjct: 4173 -PNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQ 4231
Query: 3735 ----GKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYS--ESGI 3788
KIPW AL + + YGGRV + +DQR L T L+R F+ + + ++K + G
Sbjct: 4232 NISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGH 4291
Query: 3789 YFAPMADSL--QEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSS 3846
M D + +EF ++E LP P G+ NA V + +I+ +L++Q
Sbjct: 4292 KDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLED 4351
Query: 3847 TGG------EGKSNDEIVQE----LVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTT 3896
E K+ + + + ++ T L + + S + ++ + L
Sbjct: 4352 EDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFR 4411
Query: 3897 VLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPS 3956
+EV LL+ + L + + G + + + N + +P WS+ P+
Sbjct: 4412 FFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPA 4471
Query: 3957 LKPLGSWVKDL---ILRTSFVDLWLKRGQPKS-----YWISGFFFPQGFLTGTLQNHARK 4008
+ WV D I + + L G K + G F P+ ++T T Q A+
Sbjct: 4472 GMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQA 4531
Query: 4009 YNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDAS 4068
+ ++EL + +V + Q A ++A FG V G+ + +
Sbjct: 4532 NSWSLEELCLEVNVTTS---QGATLDAC---SFG-----------------VTGLKLQGA 4568
Query: 4069 RWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHST 4128
++ ++ + +A+ + L + + Q N + ++ P+Y RA +
Sbjct: 4569 TCNNNKLSLSNAISTAL--PLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLI------- 4619
Query: 4129 NFVVTVLLPSKRSKDYWIAKGSALLC 4154
F V + +K + +G A+LC
Sbjct: 4620 -FTVDFEIATKEDPRSFYERGVAVLC 4644
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1305 bits (3377), Expect = 0.0
Identities = 947/3400 (27%), Positives = 1656/3400 (48%), Gaps = 311/3400 (9%)
Query: 868 NFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQE-----WL--KSKFDCLDPEVLN 920
+F++E F +S +++ +W + E+ + QE W+ ++K + ++N
Sbjct: 1106 HFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMN 1165
Query: 921 GQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTV 980
+L K + + +L+ +V+K K +P++ +R L HW + +
Sbjct: 1166 WH--------DRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFR-- 1215
Query: 981 DATLVDAEIPLTLERL---SQLHVFDF----GQEIQDISGQASGEAALEAILKKVEDSWK 1033
L+ +LE+L L V D +++D++ +A GE + L++++
Sbjct: 1216 ---LLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGV 1272
Query: 1034 TTEFVILPHRDSKD--VFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQL 1091
F ++ + DS+ + ++ DI + D+ + +L S Y + +V W+++L
Sbjct: 1273 GAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKL 1332
Query: 1092 ALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNA 1151
A ++ L+ QR W+YLE IF + LP E F +VD+ ++ IM + +
Sbjct: 1333 AELDEYLQNLNHIQRKWVYLEPIFG----RGALPKEQTRFNRVDEDFRSIMTDIKKDNRV 1388
Query: 1152 LRAATQPGLLETFQNNNALLDQIQKC---LEAYLESKRVIFPRFYFLSNDELLEILAQTR 1208
T G+ + +LDQ+Q+C L +LE KR FPRFYF+ +D+LLEIL Q+
Sbjct: 1389 TTLTTHAGIRNSLLT---ILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQST 1445
Query: 1209 NPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLG 1268
NP +Q HL+K F I+ + F EK + I AM S EGE V
Sbjct: 1446 NPSVIQSHLKKLFAGINSVCF----------------DEK--SKHITAMKSLEGEVVPFK 1487
Query: 1269 KGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIA---DYQGKLRTDWVVAGHPSQVILTVS 1325
+ NVE WL + M +L +L K + QG + PSQ++
Sbjct: 1488 NKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLF----PSQILCLAE 1543
Query: 1326 QIMWCRDLTECL--------ETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNI 1377
QI + D+ + ET+ N ++ N + + + N + I++ L
Sbjct: 1544 QIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLK------ 1597
Query: 1378 LTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYE 1437
ALI +H D+V +L Q +V T E + W++QLR+Y D C +M S++ Y YE
Sbjct: 1598 --ALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSD-HTCCVQMVDSEFQYTYE 1654
Query: 1438 YLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFN 1497
Y G +LV TPLTD+CYL L A+++ LGG P GPAGTGKTE+ K L L Q +VFN
Sbjct: 1655 YQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFN 1714
Query: 1498 CSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMF 1557
C +G+D K MGR F GL + GAW CFDEFNR++ VLS ++ Q+ TI++A +
Sbjct: 1715 CDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCEL 1774
Query: 1558 EGREIKLVMTCAAFITMNP---GYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEG 1614
G+E+++ FITMNP GY GR +LPDNLK LFRP AM P+ LIAEVILYSEG
Sbjct: 1775 LGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEG 1834
Query: 1615 FESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRE------NPDLNE 1668
F+ +K+L+RK+ ++ L E L+ Q HYD+G+RA+K+VL +G+L R+ + NE
Sbjct: 1835 FKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANE 1894
Query: 1669 DVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQP 1728
++++AL+ + + KF D F +I D+FPG+++ E +Y L + + V N +
Sbjct: 1895 SHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEI 1954
Query: 1729 EMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKT 1788
++K ++ YE + R GV++VGP+G GK+T++R+L L K+ VK
Sbjct: 1955 IPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKV---------VKQ 2005
Query: 1789 YVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIEN 1848
Y +NPK++ +L G ++ T EW DG++ S R V + + WII DG +D WIE+
Sbjct: 2006 YTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIES 2065
Query: 1849 MNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPY 1908
+N+VLDDN++L + + ERI+ P ++ +FE DL ASPAT+SR GM+F+ EE
Sbjct: 2066 LNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSL 2125
Query: 1909 VKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLES 1968
+K+W++ + + +I + F++ L ++ K+ V+ S V T+ L
Sbjct: 2126 IKSWLRNQPAEYRNNLENWIGDYFEK----ALQWVLKQNDYV---VETSLVGTVMNGLSH 2178
Query: 1969 LILGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDAR 2028
L +D F+ + LGGNL F + ++P
Sbjct: 2179 LHGCRDH---------------DEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESP--- 2220
Query: 2029 LPNSGDLWSIHMDFDTKRL------DPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLM 2082
P+ + D RL P + F +P ++ T D R
Sbjct: 2221 -PDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLP----VIQTPDMQRGLDYF 2275
Query: 2083 EKLLA--VKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIE 2140
+ L+ K + G G GK ++ + ++++ + ++ SAQT+S + +
Sbjct: 2276 KPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQ---IATVHCSAQTTSRHLLQKLS 2332
Query: 2141 SK---LERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK 2197
+ + +R+V+++ D+N+P+LD++G+ + L+Q + GFYD N
Sbjct: 2333 QTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDEN- 2391
Query: 2198 LFWKEIQDVTIISACAPPGG-GRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAIL----- 2251
L W ++++ I+++ + G GR+ +T RF + + P L+ I+ A L
Sbjct: 2392 LEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLH 2451
Query: 2252 ----NGFLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGI 2307
N + + A S+V+ ++ K +VD SHY F L++ V G+
Sbjct: 2452 KNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVD-----DYSHYFFTPCILTQWVLGL 2506
Query: 2308 LQCD--PGTIREEIQ-IFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDL 2364
+ D G+ + + + +E +R+F D+++ ++ H F +ILT + +G I
Sbjct: 2507 FRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILD 2566
Query: 2365 EYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTA---------NVLQDYLDDYNLTNPK 2415
+ + +G GA A +P K +V++ L Y N +
Sbjct: 2567 NMSDSFYVTWGARHNSGARAAPG--QPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDN-Q 2623
Query: 2416 EVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSR 2475
+ ++ F + +E++SRI R++ G+ LL G G G++++T L +H+ G ++SR
Sbjct: 2624 NLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISR 2683
Query: 2476 GYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDE 2535
GY F DL+ + ++AG+E + +V L D Q V FLE IN++L+SGEVP L+ +E
Sbjct: 2684 GYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEE 2743
Query: 2536 LEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSL 2595
LE +L + +A + +G VF YF +++Q LHIVL M F C P+L
Sbjct: 2744 LEPLLLPLKDQASQ----DGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPAL 2799
Query: 2596 VNCCTIDWFVQWPREALLSVSKTFFSQVDAG----NEELKEKLPLMCVNVHLSVSSMAER 2651
C + W W ++ + + FS+ G +++ KE+ V+ S +
Sbjct: 2800 HKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLL-- 2857
Query: 2652 YYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKL 2711
+E + Y TP+ Y+ +++Y ++ S K+K+++ + ++ G++KL E LVD++
Sbjct: 2858 -IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNR 2916
Query: 2712 DLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDE---ATAKVKAEETQAIADD 2768
+L K ++ +A ++ + V + A + + ++ + A VK EE + DD
Sbjct: 2917 KAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDD 2976
Query: 2769 AQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNA-KPDWPS 2827
+L E P ++ A A+ ++ +SEIR PPD++ ++E + L+ W S
Sbjct: 2977 ---ELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVS 3033
Query: 2828 AKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYI--NNPDFVPEKVEKVSKACKSMCMWV 2885
K L + + +D NI +I +++ + N F P+ ++ S A + WV
Sbjct: 3034 MKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWV 3093
Query: 2886 RAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVN 2945
+A YS V++ + P + ++ L T R+ + LL V ++ L++++ +
Sbjct: 3094 KANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTS 3153
Query: 2946 EKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAY 3005
E L ++ + + A L L+ E RW + + EE++ + +AAA + Y
Sbjct: 3154 EAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITY 3213
Query: 3006 YGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTEN 3065
A R++ +E W + LE F L L E W ++GLP D +S EN
Sbjct: 3214 LSAAPESLRKTCLEEWTKSA-GLE-----KFDLRRFLCTESEQLIWKSEGLPSDDLSIEN 3267
Query: 3066 GILVTQ-------GRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRL 3118
+++ Q R P +IDP QA W++ S L++I DSNF+ LE ++R
Sbjct: 3268 ALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRF 3327
Query: 3119 GLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHY 3178
G ++++E+ + ++P L P+L + + G R ++++GD IDY++ FR +++T+ PNP
Sbjct: 3328 GKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFI 3386
Query: 3179 LPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEK 3238
P+ VT +NFT T+SGL QLL+ ++ EKP LEEQ+ KL+ + K QL +EE
Sbjct: 3387 PPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEES 3446
Query: 3239 ILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQG 3298
+L L TS+GNIL+N++LI++L +K +S I+ L+E+ + ++ R+ Y P+A
Sbjct: 3447 LLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESA 3506
Query: 3299 SVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNV 3358
S MYF+I+ LS+I+ MY++SL F +LF ++ +EN +QR+ L+ Y +
Sbjct: 3507 SKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYI 3566
Query: 3359 SRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFF--------LRGSAGLEKERPPKPEA 3410
R LF+ +L+++ M + + EW+ F LR + +K R P
Sbjct: 3567 CRCLFKADQLMFALHFVRGMHPE--LFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPS- 3623
Query: 3411 PWLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDK 3470
W+ +A L+ + P L Q + ++ + TY N S + E
Sbjct: 3624 -WIDQERSWAVATLKIALP---SLYQTLCFEDAAL----WRTYYN------NSMCEQEFP 3669
Query: 3471 HMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLP 3530
+ +K +S F ++++++ + +++ A+ F + LG + + P++L
Sbjct: 3670 SILAKK-----------VSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLK 3718
Query: 3531 TLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAM 3590
LY++ P++ I+S G+DP Q A E +++GQGQ +A +M+K+
Sbjct: 3719 RLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECA 3778
Query: 3591 KSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSV 3650
++G+W+ L+N HL VSW+ +E+ + T KDTFRL+L++ F +LQ+S+
Sbjct: 3779 RNGDWLCLKNLHLVVSWLPVLEKELNTLQP-----KDTFRLWLTAEVHPNFTPILLQSSL 3833
Query: 3651 KVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGW 3710
K+T E P GL+ N+ R + TP + + +F + +FHA QER+ + P GW
Sbjct: 3834 KITYESPPGLKKNLMRTYESWTPEQISKKDNTHR-AHALFSLAWFHAACQERRNYIPQGW 3892
Query: 3711 NICYEFNDSDRECALLNL-KLYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILK 3769
YEF+ SD + +L+ + W+ + + YGGR+ + +D R L++ LK
Sbjct: 3893 TKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLK 3952
Query: 3770 RFFSPETLEEDYKYSESGIY----FAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLV 3825
+FF+ ++ + ++ I+ P + S+ +++ IE +P D P FG+ N
Sbjct: 3953 QFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARS 4012
Query: 3826 FQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVK 3885
Q +S +I+ L + RS T G K + EI ++ V + +KL V
Sbjct: 4013 SQRMISSQVISQ-LRILGRSITAG-SKFDREIWSNELSPV-LNLWKKLNQNSNLIHQKVP 4069
Query: 3886 DLQGRLNS--LTTVLGQEVDRFN--NLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFL 3941
R S L+ ++ +++FN L++ +H SL L+K I G ++S E++K+ ++ L
Sbjct: 4070 PPNDRQGSPILSFII---LEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALL 4126
Query: 3942 NNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYW-----ISGFFFPQG 3996
N + P W + PL +++ L+ R + W+ + + ++ +S F P
Sbjct: 4127 NQKCPLAWQSKWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDT 4185
Query: 3997 FLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPED 4056
FL Q AR +D L F + +++ + QE + +++
Sbjct: 4186 FLNALRQETARAVGRSVDSLKF----VASWKGRL------------QEAKLQIKI----S 4225
Query: 4057 GVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLP-VVHFEPQQ---NYKPSPTLYHCPLY 4112
G+L+ G D ++ + ++ ++ VLP + + PQ Y P + P+Y
Sbjct: 4226 GLLLEGCSFDGNQLSENQLD-----SPSVSSVLPCFMGWIPQDACGPYSPDECI-SLPVY 4279
Query: 4113 KTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSAL 4152
T+ V + +P ++D WI G+AL
Sbjct: 4280 ----------TSAERDRVVTNIDVPCGGNQDQWIQCGAAL 4309
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 1276 bits (3301), Expect = 0.0
Identities = 776/2107 (36%), Positives = 1174/2107 (55%), Gaps = 154/2107 (7%)
Query: 505 EDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFT 564
+D+ +P+F EL + F P+ +D D +L V + +V + S+ +
Sbjct: 318 KDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTI--PSWLSGTS 375
Query: 565 SPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATF-EKFQI 623
+P +N E + H + +K + E AR + T+ EK+
Sbjct: 376 TP-VNLDTE--------------LPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
Query: 624 FFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTRLLREKL 683
+++ + ++ + ++E +EK+ + + L + ++ +D L+ L
Sbjct: 421 LLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGL 480
Query: 684 IPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDE---- 739
+L + + +K+ + I E + + VP TT E + + ++++
Sbjct: 481 TNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTV 540
Query: 740 -IQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFAT--MKPSIV---------AVR 787
I+E I +++ QM ++ + P ED A+ AT M P + +
Sbjct: 541 GIEELILRIQESKR---QMSYFLDVFLFPQ--EDLALNATVLMWPRKINPIFDENDELIE 595
Query: 788 NAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNN 847
NA K + + ++ + + + + +L+ + D+ Q +I+
Sbjct: 596 NAKHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEA 655
Query: 848 LQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWL 907
+Q + + ++ FK E++K+ L+++ ++ Q ++ +W + ++ W+
Sbjct: 656 VQFINKE-----------EELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWM 704
Query: 908 KSKFDCLDPEVLNGQVSKYAK--------FVTQLEKGLPPNSVVPQLK-YKVEKMKEKLP 958
F L+ E + V ++++ F T+L+K L + + + EK++E+
Sbjct: 705 DGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPK 764
Query: 959 VIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGE 1018
+ ++ARHW I + V L + TL ++ +L++ + ++ + IS AS E
Sbjct: 765 DNATITMCRMRARHWKQISEIVGYDLTP-DSGTTLRKVLKLNLTPYLEQFEVISAGASKE 823
Query: 1019 AALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLG 1078
+LE + + +W+ F I +RD+ V IL D+IQ +LDD I T+ S ++
Sbjct: 824 FSLEKAMNTMIGTWEDIAFHISLYRDT-GVCILSSVDEIQAILDDQIIKTQTMRGSPFIK 882
Query: 1079 PLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSW 1138
P + + W+ +L +T++EWL Q WLYLE IF + DI +Q+P E + F VD+ W
Sbjct: 883 PFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHW 942
Query: 1139 KEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSND 1198
++IM+ + P L A + GLLE QN N LL++I K L AYLE KR+ FPRF+FLSND
Sbjct: 943 RDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSND 1002
Query: 1199 ELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAML 1258
E+LEIL++T++P VQPHL+KCF+ I+KLEF +P +D I AM
Sbjct: 1003 EMLEILSETKDPLRVQPHLKKCFEGIAKLEF---------LPNLD----------IKAMY 1043
Query: 1259 SPEGERVSLGKGLK---ARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAG 1315
S EGERV L + ARG VE+WL +VE+ M S+ + AA Y R DWV
Sbjct: 1044 SSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWV-RE 1102
Query: 1316 HPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHR 1375
P QV+L +SQ+ W + E + S + LK + K +LN + +V+G L K R
Sbjct: 1103 WPGQVVLCISQMFWTSETQEVI----SGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTR 1158
Query: 1376 NILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYG 1435
L AL+TIDVHARD+V ++++ V F W QLRYYW+ + N R+ Y
Sbjct: 1159 TTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENE--NARVRIINCNVKYA 1216
Query: 1436 YEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVV 1495
YEYLG PRLVITPLTDRCY L+GA L+LGGAP GPAGTGKTETTKDLAKALA+QCVV
Sbjct: 1217 YEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVV 1276
Query: 1496 FNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRF 1555
FNCSDGLDY MG+FF GLA SGAW CFDEFNRI++EVLSV+AQQ++ I+ A KL F
Sbjct: 1277 FNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVF 1336
Query: 1556 MFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGF 1615
+FEG E+KL C ITMNPGYAGR+ELPDNLK LFR AMMVPNYALIAE+ LYS GF
Sbjct: 1337 VFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGF 1396
Query: 1616 ESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRA 1675
+++ L+ K+ Y+LCSEQLS Q HYD+GMRAVK+VLV AG+LK + P+ NED++L+R+
Sbjct: 1397 LNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRS 1456
Query: 1676 LQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRK 1735
++D N PKFL+ D LF+GI SDLFPG+++PE DY + N NLQP + K
Sbjct: 1457 IKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEK 1516
Query: 1736 VIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGI---ENSFYQAVKTYVLN 1792
+IQ YE M+VRHG MLVG KT V +LA+TL + + G E Y+ V N
Sbjct: 1517 IIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTV-----N 1571
Query: 1793 PKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTV 1852
PKSITMG+L+G+ + ++ EW DG++A + R + D KW++ DGP+D LWIE+MNTV
Sbjct: 1572 PKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTV 1631
Query: 1853 LDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTW 1912
LDDNK LCL + E I+++PQ+ ++FE DL ASPATVSRCGM++++P +L W P V +W
Sbjct: 1632 LDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSW 1691
Query: 1913 MKGISKKLTE-ETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLIL 1971
+ + L E E Q + LF + L N++ + Q++ T + +L+ LI
Sbjct: 1692 LNSLKGPLCEPEYQALLRGLFAWLIPPSL---NQRVE--LFQLNYLYTTIVSKILKILIT 1746
Query: 1972 GKDG-----VNLAMEQTKLNTILCQ--TFVFCYLWSLGGNLTENYYDSFDTFIRT----Q 2020
+ V L + T + L Q F+F +WS+GG+ + FDTFIR +
Sbjct: 1747 FRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGK 1806
Query: 2021 FDDNPDARLPNSGDLWSIHMD---------FDTKRLDPW----ERIIPTFKYNRDVPFFE 2067
D+NP +P+S W D ++ K W E I T ++ + +
Sbjct: 1807 DDENP---VPDSVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQD 1863
Query: 2068 MLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFS 2127
++VPT DT+RY +LM+ + +LF G TG GKSV K L E Y P Y+N S
Sbjct: 1864 IIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLS 1923
Query: 2128 AQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQ 2187
A+TS+ + Q II ++L+++RK + G P K+ +IF+DD+NMP L++YG+QPPIELLRQ+
Sbjct: 1924 ARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFF 1983
Query: 2188 DFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIF 2247
D G +YD + D+ +I+A PPGGGRNPVTPR IRHF++ + S+ ++ +IF
Sbjct: 1984 DCGHWYDLKDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIF 2043
Query: 2248 QAILNGFL--SDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQ 2305
+I+ +L +FPP + IV ++EIY + +LLPTP KSHY FNLRD S+ ++
Sbjct: 2044 SSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIR 2103
Query: 2306 GILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLE 2365
G L + + + + RLF HE RVF+DRLIN++D+ + + + HF +
Sbjct: 2104 GCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSI 2163
Query: 2366 YF----LNKPI--------IFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTN 2413
+ N P+ +FGD++ + DR+Y ++P+I ++V+ LD+YN T+
Sbjct: 2164 FSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTH 2223
Query: 2414 PKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIEL 2473
+ LV F+ +EH+SRI R+++Q GNALLVG+GG+G+QSLTRLA + Q E+
Sbjct: 2224 KTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEI 2283
Query: 2474 SRGYNYDSFHEDLRKLYKMA---GVEDKNMVFLFTDTQIVVEEFLEDIN-NILNSGEVPN 2529
S+ Y + + ED++ + + D L + + + F ++ NI S
Sbjct: 2284 SKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRYLNDHFTYNLYCNICRS----- 2338
Query: 2530 LFEKDEL 2536
LFEKD+L
Sbjct: 2339 LFEKDKL 2345
Score = 636 bits (1641), Expect = 0.0
Identities = 345/882 (39%), Positives = 509/882 (57%), Gaps = 63/882 (7%)
Query: 3288 REKYRPVATQGSVMYFVIASLSEIDPMYQY--SLKYFKQLFNTTIETSVKTENLQQRLDV 3345
R+ +AT + M+ +S+ M ++ +K F + T K++ L++RL
Sbjct: 2263 RQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRY 2322
Query: 3346 LLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERP 3405
L + Y N+ R LFE+ KL++SF+LC ++ + + E F L G L K
Sbjct: 2323 LNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSL-KSAE 2381
Query: 3406 PKPEAPWLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKM 3465
P+ WL +W C E FP F GL Q+ H R
Sbjct: 2382 KNPDPTWLQDKSWEEICRASE-FPAFRGLRQHFCEHIYEWR------------------- 2421
Query: 3466 KHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETP 3525
E ++ A P L+ K+I+++C + +K+ A+T++V + LGK+F+E P
Sbjct: 2422 --EIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPP 2479
Query: 3526 PVDLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGYS-ERVQSISLGQGQGPIAEK 3584
P DL Y D +C PL+F+LS G+DPM + +FA + S + Q+ISLGQGQGPIA K
Sbjct: 2480 PFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAK 2539
Query: 3585 MVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVT 3644
M+K A++ G WV LQNCHLAVSWM +E++ + FT +FRL+L+S PS+ FPVT
Sbjct: 2540 MIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTS--ETCNSSFRLWLTSYPSSKFPVT 2597
Query: 3645 VLQNSVKVTNEPPKGLRANIRRAFTE---MTPSFFEENILGKK--WRQIIFGICFFHAII 3699
+LQN VK+TNEPP GLR N+ +++ P FF+ GK+ W +++FG+CFFHA++
Sbjct: 2598 ILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFK-GCRGKELAWEKLLFGVCFFHALV 2656
Query: 3700 QERKKFGPLGWNICYEFNDSDRECALLNLKLYCKE-GKIPWDALIYITGEITYGGRVTDS 3758
QERKKFGPLGWNI Y FN+SD ++ L+L+ E IP++A+ Y+TGE YGGRVTD
Sbjct: 2657 QERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDD 2716
Query: 3759 WDQRCLRTILKRFFSPETLEED-YKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFG 3817
WD+R L T+L F++ +E YK+S SG YFAP + +++ ++I+ LP PEIFG
Sbjct: 2717 WDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFG 2776
Query: 3818 MHENANLVFQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEG 3877
+HEN ++ ++T TL ++L Q S G S D+I+ E+ + ++P ++E
Sbjct: 2777 LHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEM 2836
Query: 3878 ASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVY 3937
A V+ + S+ TVL QE++RFNNL+ I +L L KAI G VVM +E +
Sbjct: 2837 ALRKYPVRYEE----SMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALS 2892
Query: 3938 NSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGF 3997
S L +VP +W+ +YPSLKPLGS++ D + R +F+ W G+P +W+SGFFF Q F
Sbjct: 2893 GSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAF 2952
Query: 3998 LTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDG 4057
LTG +QN+ARKY PID L +++ VIP+ D SPEDG
Sbjct: 2953 LTGAMQNYARKYTTPIDLLGYEFEVIPS----------------------DTSDTSPEDG 2990
Query: 4058 VLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGA 4116
V +HG+++D +RWD + ++ + P + ++P++ +P Q + Y CPLYKT
Sbjct: 2991 VYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSE 3050
Query: 4117 RAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQLSE 4158
R GTLSTTGHSTNFV+ +LL + + +WI +G ALLCQL +
Sbjct: 3051 RKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLDD 3092
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 400 bits (1027), Expect = e-110
Identities = 256/865 (29%), Positives = 423/865 (48%), Gaps = 86/865 (9%)
Query: 3308 LSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHK 3367
LS+I PMYQ+SLK F +F +E + E+L++R+ L++ + Y RGLFE K
Sbjct: 4 LSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDK 63
Query: 3368 LIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEES 3427
L Y L +++ ++ E +F LR P + +L W A L S
Sbjct: 64 LTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVE----FLSHQAWGAVKVLS-S 118
Query: 3428 FPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAG 3487
F L ++I + + W+ + + + EKE Q+ W
Sbjct: 119 MEEFSNLDRDIEG--------------SAKSWKKFVESECP------EKEKLPQE-WK-N 156
Query: 3488 LSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILS 3547
++ +L +++ + +++ +AL DFV E LG +++ +D T +++ TP+ FILS
Sbjct: 157 KTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILS 216
Query: 3548 TGSDPMGAFQRFARESGYS---ERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLA 3604
G DP+ + R+ GY+ + ++SLGQGQ +AE + A K G+WV LQN HL
Sbjct: 217 PGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLV 276
Query: 3605 VSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPS-----NTFPVTVLQNSVKVTNEPPKG 3659
W+ +E+ ++ ++ FR+F+S+ P+ + P +L+NS+K+TNEPP G
Sbjct: 277 AKWLSTLEKKLEEHSENSHP---EFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTG 333
Query: 3660 LRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDS 3719
+ AN+ +A T E +++ I+F +C+FHA++ ER+KFGP GWN Y FN
Sbjct: 334 MHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTG 393
Query: 3720 DRECALLNLKLYCK-EGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLE 3778
D ++ L + + K+P+D L Y+ GEI YGG +TD WD+R RT L F PE LE
Sbjct: 394 DLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLE 453
Query: 3779 EDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTI 3838
+ + + P + YI+ + P ++G+H NA + F + + L T+
Sbjct: 454 GELSLAPG--FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTV 511
Query: 3839 LEVQPRSSTG--GEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLT- 3895
LE+QPR S G G + +E V+ L+ + RV ++ + +L ++ T
Sbjct: 512 LELQPRDSQARDGAGATREEKVKALLEEILERVTDEFN---------IPELMAKVEERTP 562
Query: 3896 --TVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTA 3953
V QE R N L + I SL L + G + M+ ME + N+ + VP W+ A
Sbjct: 563 YIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRA 622
Query: 3954 YPSLKPLGSWVKDLILRTSFVDLWL-KRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLP 4012
YPS L +W DL+ R ++ W P + W++GFF PQ FLT +Q+ ARK P
Sbjct: 623 YPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWP 682
Query: 4013 IDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDD 4072
+D+++ + + R++ P +G +HG+FM+ + WD
Sbjct: 683 LDQMALQCDMTKKNREEFR--------------------SPPREGAYIHGLFMEGACWDT 722
Query: 4073 KEMVIEDALPGQMNPVLPVVHFEP-QQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFV 4131
+ +I +A + P +PV+ + + + ++Y CP+YKT R T +V
Sbjct: 723 QAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPT---------YV 773
Query: 4132 VTVLLPSKRSKDYWIAKGSALLCQL 4156
T L +K + W+ G ALL Q+
Sbjct: 774 WTFNLKTKENPSKWVLAGVALLLQI 798
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 298 bits (764), Expect = 6e-80
Identities = 366/1691 (21%), Positives = 665/1691 (39%), Gaps = 249/1691 (14%)
Query: 889 KQLLWDSFSEWDKLQQEWLKSKFDCLDP----EVLNGQVSKYAKFVTQLEKGLPPNSVVP 944
+Q +W + + EW F P E G +++ A+ T LE P V+
Sbjct: 1018 QQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSP---VLQ 1074
Query: 945 QLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDF 1004
+ + + LP++ L + ++ + + + + + LTL +L + +F
Sbjct: 1075 HCMRILGEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEF 1134
Query: 1005 GQEIQDISGQASGEAALEAILKKVEDSWKTTEFVIL------------PHRDSKDV---- 1048
I + + + +++++ W+ + +L R + V
Sbjct: 1135 ADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSP 1194
Query: 1049 -----------FILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQT 1097
FIL ++Q + +S ++ + + G L EW +
Sbjct: 1195 QWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGAL 1254
Query: 1098 LEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNR--------LP 1149
LE WLT Q+ W++L + + IQ F +D ++ +MR +P
Sbjct: 1255 LEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVP 1314
Query: 1150 NALRAATQPG--LLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQT 1207
+A R+ G L + Q + L+ I LE+ L FPR +FLS+ EL+ +LA
Sbjct: 1315 SAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAAR 1374
Query: 1208 RNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSL 1267
Q +R+CF + + F P E + P + LA+L GE V L
Sbjct: 1375 LESCEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKL 1434
Query: 1268 GKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIA----------------DYQGKLRTD- 1310
L ++ +WL +E+ + +L + + +A Q KL
Sbjct: 1435 QGPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQL 1494
Query: 1311 ----WV--VAGHPSQVILTVSQIMWCRDLTECL--------ETEHSNHIQALKNFEKVNF 1356
W+ V P Q +L +++W ++ E L + H ++ L NF
Sbjct: 1495 YVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMHMRKLEVLVNF----- 1549
Query: 1357 ERLNALAAIVQG-SLPKLHR-NILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRY 1414
+ A A G SLP + + ++L+AL+ + V RDI L Q +V + F W RQL+Y
Sbjct: 1550 --MRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKY 1607
Query: 1415 YW----------------------DIDLDNCVARMALSQYTYGYEYLGACPRLVITP--L 1450
+ + C + + Y YEYLG PRL P L
Sbjct: 1608 HLGSPHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLL 1665
Query: 1451 TDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRF 1510
+R L L+ AL+ G GP G GK LA+AL Q V+ CS ++ + + +
Sbjct: 1666 PERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNY 1725
Query: 1511 FSGLAQSGAWCCFDEFNRIDIEVLSVIAQQL------------------ITIRNAKAAKL 1552
+G Q GAW ++ +++ +LS + Q+L TI + L
Sbjct: 1726 LNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLL 1785
Query: 1553 SRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYS 1612
FE + + + + + A + +P NL L RP A+ +P+ +AE+ L
Sbjct: 1786 GSSFFEKHHVSVRLGYGCLLVLR---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLG 1842
Query: 1613 EGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVL---VMAGSLKRENPDLNED 1669
G + +A ++++ + L E +S + +K +L + ++ +E P +
Sbjct: 1843 AGMRDAFQMATRLSKFFSLERELVS--GPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKP 1900
Query: 1670 VVLIRALQDSNL---PKFLTDDAL---LFSGIISDLFPG---VQIPEHDYGILQSTIVDV 1720
L A++++ L P F + L G++ LFP V Y +++ +V+
Sbjct: 1901 RSL-AAIEEAALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEE 1959
Query: 1721 MNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKL-GIE 1779
+ + L P ++ + Q + + G++L+GP G GKTT + L + L +
Sbjct: 1960 LQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTS 2019
Query: 1780 NSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHK------ 1833
Q V+ L P ++ E G + W G+ +RAA + K
Sbjct: 2020 TQGCQPVEITHLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEES 2077
Query: 1834 -----WIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPA 1888
WII DG + W++++ +L + L L + ++I P +L EV D SP
Sbjct: 2078 IGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPT 2137
Query: 1889 TVSRCGMVFVDPEELKWMPYVKTWMKGI--SKKLTEETQEYILNLFQRYVDEGLHFINKK 1946
V C +V+ E+ W + M + +L T + ++ + V L F+ +
Sbjct: 2138 VVGCCALVWCGGEQ-TWQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQ 2196
Query: 1947 CSQAIPQV--------DISKVTTLCCLLESLI---------------------------- 1970
++ QV +++VT++ +L SL+
Sbjct: 2197 GVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFR 2256
Query: 1971 ------LGKDGVNL--AMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIR---T 2019
L + V+ ++ + + + +F+F +W G +L ++ FDTFIR +
Sbjct: 2257 SSKSSFLNRSQVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSIS 2316
Query: 2020 QFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYG 2079
+ + P+ P S ++ +H+ + L P+ + + F P+ T R
Sbjct: 2317 RLSNYPEP--PPSALVFDLHVSPEDGTLVPFTGQYLSSHIKGTLGTFH---PSIQTERLL 2371
Query: 2080 YLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEII 2139
Y+++ LL+ VL G GKS + L+ Y P++ FS+ I
Sbjct: 2372 YVVDLLLSGGQPVLLAGEAATGKSAFVEVLVEP-HHPYIYSPIHPAFSSSHLRLLLSRGI 2430
Query: 2140 ESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGS-QPPIELLRQYQDFGGFYDRNKL 2198
+ + + + ++ ++DL++ D S QP +E LRQ D G Y + L
Sbjct: 2431 QGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTL 2489
Query: 2199 FWKEIQ-DVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSD 2257
+ +Q V ++ PG P+ PR R F++L L ++ +L + I+ +L
Sbjct: 2490 ELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLER 2549
Query: 2258 FPPAVKQ--TASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLS-------------- 2301
FP ++ A +V ASVE + + +P+P HY F+L +S
Sbjct: 2550 FPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTG 2609
Query: 2302 --------------KCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFH 2347
+ V G+ + + RL+ HE QR F DRL + ++ Y
Sbjct: 2610 SRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCA 2669
Query: 2348 VILTEMANKHF 2358
+L +A F
Sbjct: 2670 KLLLVVAQSVF 2680
Score = 139 bits (349), Expect = 8e-32
Identities = 156/718 (21%), Positives = 289/718 (40%), Gaps = 76/718 (10%)
Query: 2427 EHVSRIARMIRQERGNALLV-GVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHED 2485
+HV+R+ R++ + R + LL+ G GTG+ + LA+ IC + + ++ +
Sbjct: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSG---SEEAILQC 2926
Query: 2486 LRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRP 2545
LR AG+ + + L + L + + SG P + + +L+++ P
Sbjct: 2927 LRDASWHAGMLSQPVALLVPSGVDLTT--LHRLLALATSGSFPGQYTEADLDRI-GEHLP 2983
Query: 2546 RAKEVGISEGNRDE-VFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCT--ID 2602
R + +G+ + + E V Q F +V LH+ + + +F L+ T ID
Sbjct: 2984 R-ENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASID 3042
Query: 2603 WFVQWPREALLSVSKTFFS-----QVDAGN---EELKEKLPLMC---VNVHLSVSSMAER 2651
+ W + AL V++ +D G+ +L+ +P + +HLS + E
Sbjct: 3043 RYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEH 3102
Query: 2652 YYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKL--------LETN 2703
L TP ++L+ ++ +L + + +I + RV+N L L N
Sbjct: 3103 LCPALP---LVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHAN 3159
Query: 2704 ILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQ 2763
++ D LE L + + ++L + Q + E + A +
Sbjct: 3160 LIFD--------LEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQRD 3211
Query: 2764 AIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKP 2823
A+ + L++ A + L L AD EIR + PP+ V+ V +A+ L + +
Sbjct: 3212 ALQAQREAFLEQMSKAF---LEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHET 3268
Query: 2824 DWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCM 2883
W SAKQLL +F + L+ + KE I L KL + P + VS+ S+
Sbjct: 3269 GWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAA 3328
Query: 2884 WVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKG 2943
W+ A+ Y P L+ +A L A L Q ++ + AL +
Sbjct: 3329 WLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDA 3388
Query: 2944 VNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACV 3003
+AKT++ + + AAL W +QK + + G+ + +A +
Sbjct: 3389 QASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAI 3448
Query: 3004 AYYGAFTAQYRQSLIECWIQDCQSLEIPIDPS---------------------------F 3036
Y G F RQ L++ W+ C+ + + P F
Sbjct: 3449 IYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSPF 3508
Query: 3037 SLINILGDPYEIRQWNTDGLPRDLISTENGILVT-----QGRRWPLMIDPQDQANRWI 3089
S++++L E QW+ + P+ + G+L+ RWPL++DP ++A W+
Sbjct: 3509 SILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIWL 3566
Score = 103 bits (258), Expect = 3e-21
Identities = 196/1024 (19%), Positives = 382/1024 (37%), Gaps = 104/1024 (10%)
Query: 3186 VTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFT 3245
+ +++ + LE+Q+L +++ E P LE + L +R ++ EE++L ML
Sbjct: 3745 LNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLF 3804
Query: 3246 SEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVI 3305
+ + + ++ ++ EE E + V YRPV G M +
Sbjct: 3805 QNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKAL 3864
Query: 3306 ASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVN-------- 3357
+ L + P++ S + + + ++ S+K + D+ L A++
Sbjct: 3865 SQLQNLLPLFCMSPENWLAVTKQALD-SMKPREINHGEDLASHLLQLRAHLTRQLLGSTV 3923
Query: 3358 VSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAP-----W 3412
+ GL + + + + +++ G S+ E G A KP + W
Sbjct: 3924 TALGLTQVP--LVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVARPAW 3981
Query: 3413 LPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHM 3472
L W C ++ E P F GL ++ H + W+ Y +
Sbjct: 3982 LGPKAWHEC-EMLELLPPFVGLCASLAGHSSA--------------WQAYLSLS------ 4020
Query: 3473 RQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTL 3532
P LS KLIL + + E + AL DF LG+ E PT+
Sbjct: 4021 -STVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYA--PTM 4077
Query: 3533 -YQDMSCNTPLVFIL------STGSDPMGAFQRFARESGYSER-VQSISLG-QGQGPIAE 3583
++ P++ +L S P+ Q+ A + ++ +Q I+LG + P++
Sbjct: 4078 PFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSV 4137
Query: 3584 KM--VKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTF 3641
+ + AM G+W+ L NCHL W + +L+ + D L P +
Sbjct: 4138 VVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESR- 4196
Query: 3642 PVTVLQNSVKVTNEPPKGLRANIRRAFTEMT-PSFFEENI-LG-------KKWRQIIF-- 3690
V+ + ++ P A++ T+ + P F+ +++ LG + +Q+++
Sbjct: 4197 NVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQ 4256
Query: 3691 ------GICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKEGKIPWDALIY 3744
+ H ++ R+ +G ++ L P A+
Sbjct: 4257 PPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPRAAMQE 4316
Query: 3745 ITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFAPM-------ADSL 3797
+ + YGG + D+ D+ L ++ + SP + ++ + M D++
Sbjct: 4317 LAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAM 4376
Query: 3798 QEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQP-------RSSTGGE 3850
E K + LP +P + G+ E +++ L++ + P R + E
Sbjct: 4377 AECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAE 4436
Query: 3851 GKSNDEIVQ--ELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNL 3908
+ +VQ + S+Q + + + + V R L VL E + L
Sbjct: 4437 RRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNAR-RPLEGVLETEALELSQL 4495
Query: 3909 LKLIHTSLETLNKAIAGF-VVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDL 3967
+ + L+ L + + G S V ++ ++P W A +P W++ L
Sbjct: 4496 VGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQL 4555
Query: 3968 ILRTSFVDLWLKRGQPKS-------YWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKY 4020
R + +L G S + +S F P+ L A N+P
Sbjct: 4556 SRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSR 4615
Query: 4021 SVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDA 4080
+ + + + + F E + + PE G+L+ G+ + + WD ++D+
Sbjct: 4616 GSVSSQLQYKRLEMNSNPLHFRVENGPNPTV--PERGLLLIGLQVLHAEWDPIAGALQDS 4673
Query: 4081 LPGQMNPVLPV--VHFEPQQNYKPSP---TLYHCPLYKTGARAGTLSTTGHSTNFVVTVL 4135
Q +P+ PV P + P+P T+Y CP+Y G GT S N V+ +
Sbjct: 4674 PSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY-MGGPLGTAKL--QSRNIVMHLP 4730
Query: 4136 LPSK 4139
LP+K
Sbjct: 4731 LPTK 4734
Score = 62.8 bits (151), Expect = 7e-09
Identities = 64/294 (21%), Positives = 124/294 (42%), Gaps = 30/294 (10%)
Query: 190 IKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRAVTHIYN-ED 248
+K+ R + + FLY+ A R + Y+L VV + +N ++Y S + H++ E
Sbjct: 284 LKMERYLKKIHFLYLNVAPSRY---FRPYSLMVVPPDKVNP-EHYIFSPFGILHVHPVEG 339
Query: 249 IEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKSLQKNLFIV 308
E + + W + ++L IP F K+F+ W+KNVR + + QK L+ +L +
Sbjct: 340 SETMTLGTWHHHCVLWQQLQFIPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLA 399
Query: 309 NPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERLGEFRNEAK 368
PH LL I+ L +++ H+ + + + L ++ L E +++A
Sbjct: 400 VPHFGAGLLHISRL-----------LQELHSVSWLPQELDRCYELLDLQTALAEEKHKAL 448
Query: 369 YVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPT-----YGDSEKMT 423
++ R V +D YH Q + + T Y +
Sbjct: 449 RLLHRCLNLCTSILRLVHED-------TYHMQQCLQERVQNCDRIRTGQGSIYLQRVQHK 501
Query: 424 YTEQASKR--HYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTP 475
EQ K+ + ++L F RL DY+I ++ + + S + ++ ++ P
Sbjct: 502 QLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKP 555
>gi|223555933 dynein, axonemal, heavy polypeptide 14 isoform 2 [Homo
sapiens]
Length = 453
Score = 65.5 bits (158), Expect = 1e-09
Identities = 49/186 (26%), Positives = 88/186 (47%), Gaps = 20/186 (10%)
Query: 201 FLYMIPAVPRSSIEYDTYNLKVVSYENINK-NDYYTISQRAVTHIYN-----EDIEFIEI 254
F+Y +P S+ Y+ Y+L+VVS +++ I+ ++ + N +++E I
Sbjct: 175 FVYCLPRKSPKSL-YNPYDLQVVSAHTAKHCKEFWVITASFISKVINIVGSVKEVELIPT 233
Query: 255 DRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKSLQKNLFIVNPHLRP 314
W E ++ L + IFS FR KAF W+ NV+ K + L +LF+ + +
Sbjct: 234 LEWLSERRHYYLLRQFKIFSDFRMNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQT 293
Query: 315 ALLKINELC-------------YHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERLG 361
L+ I LC +LS + L ++ TY+L EF Q+ + + ++L
Sbjct: 294 CLVYIRGLCEDAINLKNYNDHENNLSAICLVKLDSSRTYSLDEFCEEQLQQATQALKQLE 353
Query: 362 EFRNEA 367
+ RN+A
Sbjct: 354 DIRNKA 359
>gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo sapiens]
Length = 597
Score = 62.8 bits (151), Expect = 7e-09
Identities = 64/294 (21%), Positives = 124/294 (42%), Gaps = 30/294 (10%)
Query: 190 IKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRAVTHIYN-ED 248
+K+ R + + FLY+ A R + Y+L VV + +N ++Y S + H++ E
Sbjct: 284 LKMERYLKKIHFLYLNVAPSRY---FRPYSLMVVPPDKVNP-EHYIFSPFGILHVHPVEG 339
Query: 249 IEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKSLQKNLFIV 308
E + + W + ++L IP F K+F+ W+KNVR + + QK L+ +L +
Sbjct: 340 SETMTLGTWHHHCVLWQQLQFIPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLA 399
Query: 309 NPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERLGEFRNEAK 368
PH LL I+ L +++ H+ + + + L ++ L E +++A
Sbjct: 400 VPHFGAGLLHISRL-----------LQELHSVSWLPQELDRCYELLDLQTALAEEKHKAL 448
Query: 369 YVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPT-----YGDSEKMT 423
++ R V +D YH Q + + T Y +
Sbjct: 449 RLLHRCLNLCTSILRLVHED-------TYHMQQCLQERVQNCDRIRTGQGSIYLQRVQHK 501
Query: 424 YTEQASKR--HYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTP 475
EQ K+ + ++L F RL DY+I ++ + + S + ++ ++ P
Sbjct: 502 QLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKP 555
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 55.5 bits (132), Expect = 1e-06
Identities = 75/375 (20%), Positives = 159/375 (42%), Gaps = 51/375 (13%)
Query: 2650 ERYYNELRRRYYTTPTSYLELINLYLSMLSE---KRKQIIS-ARDRVKNGLTKLLETNIL 2705
E N+L+ R T+ TS +E ++ L E K KQ+ R ++ L + E
Sbjct: 945 EEQVNDLKERLKTS-TSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQ 1003
Query: 2706 VDKMKLDLSALEPVLLA-KSEDVEALMEKLAVDQESADQVRNTVQE----------DEAT 2754
++K +++ + L K +E++ ++L+ +++ V+N VQE +E
Sbjct: 1004 LEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQ 1063
Query: 2755 AKVKAEETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEA 2814
A+ +E IA +AQ + L L AA+ +++L A ++ + L T +A
Sbjct: 1064 ARRDCQEQAKIAVEAQNKYEREL-MLHAAD--VEALQAAKEQVSKMASVRQHLEETTQKA 1120
Query: 2815 ISILLNAKPDWPSAKQLLGDS-----------NFLKRLLEYDKENIKPQILAKLQKYINN 2863
S LL K W +++L D RLL E + +++A +++ +
Sbjct: 1121 ESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQG 1180
Query: 2864 PDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQ 2923
P V E S+ ++++++ R++ A+ ++ +
Sbjct: 1181 PLNVSLSEEGKSQ---------------EQILEILRFIRREKEIAETRFEVAQVESLRYR 1225
Query: 2924 ALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALE------DEQVR 2977
+ +E ++Q LQD + + + AKTMA + + + + +E +E+ R
Sbjct: 1226 QRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKER 1285
Query: 2978 WEESIQKFEEEISNI 2992
E+ +Q+ + ++ +
Sbjct: 1286 LEQDLQQMQAKVRKL 1300
Score = 45.4 bits (106), Expect = 0.001
Identities = 91/420 (21%), Positives = 158/420 (37%), Gaps = 33/420 (7%)
Query: 2605 VQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTP 2664
VQ E L+ ++ + +E+ K + + +S ER NE R +
Sbjct: 21 VQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRE--CQSL 78
Query: 2665 TSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDL----SALEPVL 2720
LE +N L L+EK K++ A+DR ++ T ++ K DL L L
Sbjct: 79 RLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQEL 138
Query: 2721 LAKSEDVEALMEKLAVDQESADQVRNTVQEDEAT-AKVKAEETQAIADDAQRDLDEALPA 2779
+EDV+ L EKL + +++ + E +A+ VK E + L++
Sbjct: 139 EYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE---------KRLEQEKEL 189
Query: 2780 LDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLGDSNFLK 2839
L + N L++ K E+ + E + + N + +L N LK
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKG-----NEILELKCNLENKKEEVSRLEEQMNGLK 244
Query: 2840 RLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVE 2899
E+ +++++ +L KL++ + EK A ++ +LY E
Sbjct: 245 TSNEHLQKHVE-DLLTKLKEAKEQQASMEEKFHNELNA------HIKLSNLYKSAADDSE 297
Query: 2900 PKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKA 2959
K +L A EL L+E + ++D + L+ E K EKE L K L K
Sbjct: 298 AKSNELTRAVEELH---KLLKEAGEANKAIQDHL--LEVEQSKDQMEKEMLEKIGRLEKE 352
Query: 2960 RLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIE 3019
L+A + EE + + + V Y A+ Q L+E
Sbjct: 353 LENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLE 412
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 51.6 bits (122), Expect = 2e-05
Identities = 71/365 (19%), Positives = 147/365 (40%), Gaps = 70/365 (19%)
Query: 2670 LINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEA 2729
LI S L K +++ +RV++ +K+ E + + + +L+++ ++ +LL K DVE
Sbjct: 832 LIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVET 891
Query: 2730 LME----------------------------KLAVDQESADQVRNTVQEDEATAKVKAEE 2761
L + L V+ ++ + N + E K + EE
Sbjct: 892 LQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEE 951
Query: 2762 TQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNA 2821
++ +++ DE PA + + L E + K + ++A L+N
Sbjct: 952 DNEVSSGLKQNYDEMSPAGQISKEELQ-------HEFDLLKKENEQRKRKLQA--ALINR 1002
Query: 2822 KPDWPSAKQLLGDSNFLKRL--LEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACK 2879
K L+R+ LE + N+K + +K + ++ + + +K +K
Sbjct: 1003 K-------------ELLQRVSRLEEELANLKDE--SKKEIPLSETERGEVEEDKENKEYS 1047
Query: 2880 SMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVE-------DQ 2932
C+ + ++ + + + K +L+ + +L+ +A + QAL++Q+ +Q
Sbjct: 1048 EKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQ 1107
Query: 2933 IQALQDEYDKG---------VNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQ 2983
I LQ E + N S ++AL K +V + T + E + EE I
Sbjct: 1108 IDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKIL 1167
Query: 2984 KFEEE 2988
E+E
Sbjct: 1168 ALEKE 1172
Score = 46.2 bits (108), Expect = 7e-04
Identities = 82/408 (20%), Positives = 166/408 (40%), Gaps = 73/408 (17%)
Query: 2610 EALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTSYLE 2669
+ L + T SQ+ + ELK M ++ + ++ EL R T+ E
Sbjct: 1864 QTLENEKNTLLSQISTKDGELK-----MLQEEVTKMNLLNQQIQEELSRVTKLKETAEEE 1918
Query: 2670 LINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEA 2729
+L +++ Q+ + N + + I + ++ ++ L+ + E+ +
Sbjct: 1919 KDDLEERLMN----QLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQ 1974
Query: 2730 LM-EKLAVDQESADQVRNTVQ--EDEATAKVKAEETQAIADDAQRDL----------DEA 2776
L+ EK V+ E + +Q + E K A+E Q + + Q+++ E
Sbjct: 1975 LVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK 2034
Query: 2777 LPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLGDSN 2836
+ AL+ KAL+ + ++ + + + +A+ A+ + S K LL D+
Sbjct: 2035 ISALERTVKALEFVQTESQKDLEITKE------NLAQAVEHRKKAQAELASFKVLLDDTQ 2088
Query: 2837 F-----------LKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWV 2885
LK+ L+ +KE++K Q+ K E +E+ +
Sbjct: 2089 SEAARVLADNLKLKKELQSNKESVKSQMKQK-----------DEDLERRLE--------- 2128
Query: 2886 RAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVN 2945
+A + + + K ++ K LR + L+ T+ E Q L + + ++Q LQ+ D V
Sbjct: 2129 QAEEKHLKEKKNMQEKLDALRREKVHLE---ETIGEIQVTLNKKDKEVQQLQENLDSTVT 2185
Query: 2946 EKESLAKTMALTKARLVRAGKLTAALEDEQVRWE----ESIQKFEEEI 2989
+ + K+M+ + R + DE +WE ++IQ EEEI
Sbjct: 2186 QLAAFTKSMSSLQDDRDR-------VIDEAKKWERKFSDAIQSKEEEI 2226
Score = 34.3 bits (77), Expect = 2.6
Identities = 56/292 (19%), Positives = 122/292 (41%), Gaps = 32/292 (10%)
Query: 2674 YLS-MLSEKRKQIISARDRV--KNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEAL 2730
YLS LSEK + + + + L K L T + + + D + L + +++
Sbjct: 1410 YLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQ--LQVELCEMKQK 1467
Query: 2731 MEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQ----------RDLDEALPAL 2780
E++ + + Q++ +Q + K +E +++ ++ + L + +
Sbjct: 1468 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1527
Query: 2781 DAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLGDSNFLKR 2840
A NK D++ + + + + D ++T M+ S+L N + L LK
Sbjct: 1528 SAQNKEKDTV----LGRLALLQEERDKLITEMDR-SLLEN--------QSLSSSCESLKL 1574
Query: 2841 LLE---YDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCM-WVRAMDLYSRVVK 2896
LE DKE + +I + I EK +++ K + + + + R+
Sbjct: 1575 ALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQH 1634
Query: 2897 VVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKE 2948
VVE RQ+ + +L T A +E + L++ E +++ ++++ K K+
Sbjct: 1635 VVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQ 1686
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 50.8 bits (120), Expect = 3e-05
Identities = 78/314 (24%), Positives = 147/314 (46%), Gaps = 40/314 (12%)
Query: 2697 TKLLETNILVDKM--KLDLSALEPVLLAKSEDV----EALMEKL--------------AV 2736
T + E ++DK+ + + + +P L++ EDV E L EKL A+
Sbjct: 415 TPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKAL 474
Query: 2737 DQESADQVRNTV----QEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKALDSLDK 2792
+E+ D +++ + +E + + +K E TQ IA+ A++ + A DAA K + ++ K
Sbjct: 475 LEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAE-AEKKVQLACKERDAAKKEIKNI-K 532
Query: 2793 ADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQ 2852
+++ ++ DL+ E I L+ +KQ L +SN +K+L DKEN
Sbjct: 533 EELATRLNSSETADLLKEKDEQIRGLMEEGEKL--SKQQLHNSNIIKKLRAKDKEN--EN 588
Query: 2853 ILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAEL 2912
++AKL K + + + +++V + + R + ++ +VE + + L Q ++
Sbjct: 589 MVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHR--ENIKKLNSMVERQEKDLGRLQVDM 646
Query: 2913 DITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALE 2972
D L EK ++ D + K K+S A+ AL++ + +L+AALE
Sbjct: 647 D----ELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKE-ELSAALE 701
Query: 2973 DEQVRWEESIQKFE 2986
Q EE+ Q+ E
Sbjct: 702 KAQ---EEARQQQE 712
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 50.8 bits (120), Expect = 3e-05
Identities = 85/389 (21%), Positives = 163/389 (41%), Gaps = 60/389 (15%)
Query: 2669 ELINLYLSMLSEKRKQIISARDRV---KNGLTKLLETNILVDKMKLDLSALEPVLLAKSE 2725
EL N L++ +++ + ++++ +N K ET +++ D E LLA +
Sbjct: 991 ELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQET---FKQLQSDFYGRESELLATRQ 1047
Query: 2726 DVEALMEKLAVDQESADQVRNTV-QEDEATAKVKAEETQAIADDAQRD--LDEALPALDA 2782
D++++ EKL++ QE RN + +++ ++K + D A+++ L E AL
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQD 1107
Query: 2783 ANKALDSLDK---------ADISEIR------VFTKPPDLVMTVMEAISILLNAKPDWPS 2827
K +K A+I EI+ + +L +E+I + N K
Sbjct: 1108 IQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLK----D 1163
Query: 2828 AKQLL--------GDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACK 2879
AKQLL G ++ LK +E +K N Q + K Q + E +EK +K
Sbjct: 1164 AKQLLIQQKLELQGKADSLKAAVEQEKRN---QQILKDQVKKEEEELKKEFIEKEAK--- 1217
Query: 2880 SMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDE 2939
L+S +K E +K +A+L + + L E L V+ + Q+ Q
Sbjct: 1218 ----------LHSE-IKEKEVGMKKHEENEAKLTMQITALNEN---LGTVKKEWQSSQRR 1263
Query: 2940 YDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIA 2999
+ + + L +A+ +A + AL + ++ E I+K + ++ + +
Sbjct: 1264 VSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNT 1323
Query: 3000 AACVAYYG----AFTAQYRQSLIECWIQD 3024
A V G + ++ Q+L W +D
Sbjct: 1324 TAAVQELGRENQSLQIKHTQALNRKWAED 1352
Score = 39.7 bits (91), Expect = 0.063
Identities = 83/408 (20%), Positives = 169/408 (41%), Gaps = 42/408 (10%)
Query: 2610 EALLSVSKTFFSQVDAGNEELKEKLPL-----MCVNVHLSVSSMAERYYNELRRRYYTTP 2664
EALL SK S ++ E+L K+ +N + + +L +
Sbjct: 529 EALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQS 588
Query: 2665 TSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKS 2724
S+ + + E++ + +A+DRV + T + E N +++ K +S L+ + AK+
Sbjct: 589 ESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKT 648
Query: 2725 E---DVEALMEKLAVD-QESADQVRNTVQE------------DEATAKVK-AEETQAIAD 2767
E EA D Q D +N +Q+ D+ TAK++ +E + +
Sbjct: 649 ELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLE 708
Query: 2768 DAQRDLDEALPALDAANKALDSLDK---ADISEIRVFTKPPDLVMTVMEAISILLNAKPD 2824
++ E +L+ + L+ K AD E++ + + ++ L +
Sbjct: 709 SHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRAT 768
Query: 2825 WPSAKQLLGDSNFLK--RLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMC 2882
+KQL + + RL K I KL K + + E +S+ K
Sbjct: 769 -ELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETK--- 824
Query: 2883 MWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDK 2942
++ +L +R+ V + QK++ + L ++T+++K L +V D ++ + E++K
Sbjct: 825 --IQHEELNNRIQTTV-TELQKVKMEKEALMTELSTVKDK---LSKVSDSLKNSKSEFEK 878
Query: 2943 GVNEKESLAKTMALTKARLVRAGKLTAALED---EQVRWEESIQKFEE 2987
++ A + L K +L +E+ EQ ++S++K +E
Sbjct: 879 --ENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKE 924
Score = 38.9 bits (89), Expect = 0.11
Identities = 66/334 (19%), Positives = 132/334 (39%), Gaps = 25/334 (7%)
Query: 2671 INLYLSMLSEKRKQIISARDRVKN----GLTKLLETNILVDKMKLDLSALEPVLLAKSED 2726
IN S L E +Q+ A R+K KL++ V ++L LS LE
Sbjct: 416 INQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLE--------- 466
Query: 2727 VEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPAL---DAA 2783
E L EK+ E Q+ T Q+ + ++ + T A +AQ DL++ L + D
Sbjct: 467 -EQLKEKVTNSTELQHQLDKTKQQHQEQQALQ-QSTTAKLREAQNDLEQVLRQIGDKDQK 524
Query: 2784 NKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLGDSNFLKRLLE 2843
+ L++L + I + K + + ++A + + QL ++ L+ +
Sbjct: 525 IQNLEALLQKSKENISLLEKEREDLYAKIQA------GEGETAVLNQLQEKNHTLQEQVT 578
Query: 2844 YDKENIKPQILAKLQKYINNPDFVPEKVEKVSKA-CKSMCMWVRAMDLYSRVVKVVEPKR 2902
E +K Q + Q N D V E+ + A + + + +L S++ + E
Sbjct: 579 QLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVS 638
Query: 2903 QKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLV 2962
Q +A+ ++ ++ K A +++ + Q+ E + + A+L
Sbjct: 639 QLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQ 698
Query: 2963 RAGKLTAALEDEQVRWEESIQKFEEEISNITGNV 2996
+ + LE ++E E++ + G +
Sbjct: 699 DKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 50.1 bits (118), Expect = 5e-05
Identities = 71/376 (18%), Positives = 156/376 (41%), Gaps = 30/376 (7%)
Query: 2639 VNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTK 2698
+ V L + + +L+R+ + + E I + ++E + Q+ + ++ L +
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Query: 2699 LLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVK 2758
L + + + LE + ED+++ E+ A + A++ + + E+ K +
Sbjct: 1099 LDDEIAQKNNALKKIRELEGHISDLQEDLDS--ERAA--RNKAEKQKRDLGEELEALKTE 1154
Query: 2759 AEETQAIADDAQRDLDEALPALDAANKALDSLDK---ADISEIRVFTKPPDLVMTVMEAI 2815
E+T Q + + KALD + A + E+R K V + E +
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR--QKHAQAVEELTEQL 1212
Query: 2816 SILLNAKPDWPSAKQLLGDSNF-----------LKRLLEYDKENIKPQILAKLQKYINNP 2864
AK + KQ L N K+ +E+ K+ ++ Q+ +LQ ++
Sbjct: 1213 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV-QELQSKCSDG 1271
Query: 2865 DF----VPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLR 2920
+ + +KV K+ +S+ + + + +K+ + Q ++ R
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAE--GKAIKLAKDVASLSSQLQDTQELLQEETR 1329
Query: 2921 EK---QALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVR 2977
+K LRQ+E++ +LQD+ D+ + K++L + ++ +L + K
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1389
Query: 2978 WEESIQKFEEEISNIT 2993
EE ++F++EI N+T
Sbjct: 1390 LEEGKKRFQKEIENLT 1405
Score = 41.6 bits (96), Expect = 0.017
Identities = 78/363 (21%), Positives = 155/363 (42%), Gaps = 58/363 (15%)
Query: 2678 LSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVD 2737
L+++ ++ +A D+++ +L + +D + +DL + L++ E + ++L +
Sbjct: 1404 LTQQYEEKAAAYDKLEKTKNRLQQE---LDDLVVDLDN-QRQLVSNLEKKQRKFDQLLAE 1459
Query: 2738 QESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPA---LDAANKALDS----- 2789
+++ + + D A A+ + +ET+A++ R L+EAL A L+ NK L +
Sbjct: 1460 EKNISS-KYADERDRAEAEAREKETKALS--LARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 2790 -LDKADISE-IRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQ-----LLGDSNFLKRLL 2842
K D+ + + K + T ME + L D A + L + LK
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 2843 EYD-------KENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYS-RV 2894
E D E + Q+ +L +Y + ++ + A K + ++ ++L +
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
Query: 2895 VKVVEPKRQKLRAAQAEL--------------DITMATLREKQALLRQVEDQIQALQDEY 2940
+K E ++LR QA++ D AT +E + + +E + LQ++
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 2941 DKGVN-------EKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNIT 2993
EKE LA+ +A + + AL+DE+ R E I + EEE+
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSG-------RNALQDEKRRLEARIAQLEEELEEEQ 1749
Query: 2994 GNV 2996
GN+
Sbjct: 1750 GNM 1752
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 50.1 bits (118), Expect = 5e-05
Identities = 71/376 (18%), Positives = 156/376 (41%), Gaps = 30/376 (7%)
Query: 2639 VNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTK 2698
+ V L + + +L+R+ + + E I + ++E + Q+ + ++ L +
Sbjct: 1046 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105
Query: 2699 LLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVK 2758
L + + + LE + ED+++ E+ A + A++ + + E+ K +
Sbjct: 1106 LDDEIAQKNNALKKIRELEGHISDLQEDLDS--ERAA--RNKAEKQKRDLGEELEALKTE 1161
Query: 2759 AEETQAIADDAQRDLDEALPALDAANKALDSLDK---ADISEIRVFTKPPDLVMTVMEAI 2815
E+T Q + + KALD + A + E+R K V + E +
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR--QKHAQAVEELTEQL 1219
Query: 2816 SILLNAKPDWPSAKQLLGDSNF-----------LKRLLEYDKENIKPQILAKLQKYINNP 2864
AK + KQ L N K+ +E+ K+ ++ Q+ +LQ ++
Sbjct: 1220 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV-QELQSKCSDG 1278
Query: 2865 DF----VPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLR 2920
+ + +KV K+ +S+ + + + +K+ + Q ++ R
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAE--GKAIKLAKDVASLSSQLQDTQELLQEETR 1336
Query: 2921 EK---QALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVR 2977
+K LRQ+E++ +LQD+ D+ + K++L + ++ +L + K
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1396
Query: 2978 WEESIQKFEEEISNIT 2993
EE ++F++EI N+T
Sbjct: 1397 LEEGKKRFQKEIENLT 1412
Score = 41.6 bits (96), Expect = 0.017
Identities = 78/363 (21%), Positives = 155/363 (42%), Gaps = 58/363 (15%)
Query: 2678 LSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVD 2737
L+++ ++ +A D+++ +L + +D + +DL + L++ E + ++L +
Sbjct: 1411 LTQQYEEKAAAYDKLEKTKNRLQQE---LDDLVVDLDN-QRQLVSNLEKKQRKFDQLLAE 1466
Query: 2738 QESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPA---LDAANKALDS----- 2789
+++ + + D A A+ + +ET+A++ R L+EAL A L+ NK L +
Sbjct: 1467 EKNISS-KYADERDRAEAEAREKETKALS--LARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 2790 -LDKADISE-IRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQ-----LLGDSNFLKRLL 2842
K D+ + + K + T ME + L D A + L + LK
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 2843 EYD-------KENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYS-RV 2894
E D E + Q+ +L +Y + ++ + A K + ++ ++L +
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643
Query: 2895 VKVVEPKRQKLRAAQAEL--------------DITMATLREKQALLRQVEDQIQALQDEY 2940
+K E ++LR QA++ D AT +E + + +E + LQ++
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 2941 DKGVN-------EKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNIT 2993
EKE LA+ +A + + AL+DE+ R E I + EEE+
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSG-------RNALQDEKRRLEARIAQLEEELEEEQ 1756
Query: 2994 GNV 2996
GN+
Sbjct: 1757 GNM 1759
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 50.1 bits (118), Expect = 5e-05
Identities = 71/376 (18%), Positives = 156/376 (41%), Gaps = 30/376 (7%)
Query: 2639 VNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTK 2698
+ V L + + +L+R+ + + E I + ++E + Q+ + ++ L +
Sbjct: 1046 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105
Query: 2699 LLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVK 2758
L + + + LE + ED+++ E+ A + A++ + + E+ K +
Sbjct: 1106 LDDEIAQKNNALKKIRELEGHISDLQEDLDS--ERAA--RNKAEKQKRDLGEELEALKTE 1161
Query: 2759 AEETQAIADDAQRDLDEALPALDAANKALDSLDK---ADISEIRVFTKPPDLVMTVMEAI 2815
E+T Q + + KALD + A + E+R K V + E +
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR--QKHAQAVEELTEQL 1219
Query: 2816 SILLNAKPDWPSAKQLLGDSNF-----------LKRLLEYDKENIKPQILAKLQKYINNP 2864
AK + KQ L N K+ +E+ K+ ++ Q+ +LQ ++
Sbjct: 1220 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV-QELQSKCSDG 1278
Query: 2865 DF----VPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLR 2920
+ + +KV K+ +S+ + + + +K+ + Q ++ R
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAE--GKAIKLAKDVASLSSQLQDTQELLQEETR 1336
Query: 2921 EK---QALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVR 2977
+K LRQ+E++ +LQD+ D+ + K++L + ++ +L + K
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1396
Query: 2978 WEESIQKFEEEISNIT 2993
EE ++F++EI N+T
Sbjct: 1397 LEEGKKRFQKEIENLT 1412
Score = 41.6 bits (96), Expect = 0.017
Identities = 78/363 (21%), Positives = 155/363 (42%), Gaps = 58/363 (15%)
Query: 2678 LSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVD 2737
L+++ ++ +A D+++ +L + +D + +DL + L++ E + ++L +
Sbjct: 1411 LTQQYEEKAAAYDKLEKTKNRLQQE---LDDLVVDLDN-QRQLVSNLEKKQRKFDQLLAE 1466
Query: 2738 QESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPA---LDAANKALDS----- 2789
+++ + + D A A+ + +ET+A++ R L+EAL A L+ NK L +
Sbjct: 1467 EKNISS-KYADERDRAEAEAREKETKALS--LARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 2790 -LDKADISE-IRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQ-----LLGDSNFLKRLL 2842
K D+ + + K + T ME + L D A + L + LK
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 2843 EYD-------KENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYS-RV 2894
E D E + Q+ +L +Y + ++ + A K + ++ ++L +
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643
Query: 2895 VKVVEPKRQKLRAAQAEL--------------DITMATLREKQALLRQVEDQIQALQDEY 2940
+K E ++LR QA++ D AT +E + + +E + LQ++
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 2941 DKGVN-------EKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNIT 2993
EKE LA+ +A + + AL+DE+ R E I + EEE+
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSG-------RNALQDEKRRLEARIAQLEEELEEEQ 1756
Query: 2994 GNV 2996
GN+
Sbjct: 1757 GNM 1759
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 50.1 bits (118), Expect = 5e-05
Identities = 71/376 (18%), Positives = 156/376 (41%), Gaps = 30/376 (7%)
Query: 2639 VNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTK 2698
+ V L + + +L+R+ + + E I + ++E + Q+ + ++ L +
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Query: 2699 LLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVK 2758
L + + + LE + ED+++ E+ A + A++ + + E+ K +
Sbjct: 1099 LDDEIAQKNNALKKIRELEGHISDLQEDLDS--ERAA--RNKAEKQKRDLGEELEALKTE 1154
Query: 2759 AEETQAIADDAQRDLDEALPALDAANKALDSLDK---ADISEIRVFTKPPDLVMTVMEAI 2815
E+T Q + + KALD + A + E+R K V + E +
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR--QKHAQAVEELTEQL 1212
Query: 2816 SILLNAKPDWPSAKQLLGDSNF-----------LKRLLEYDKENIKPQILAKLQKYINNP 2864
AK + KQ L N K+ +E+ K+ ++ Q+ +LQ ++
Sbjct: 1213 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV-QELQSKCSDG 1271
Query: 2865 DF----VPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLR 2920
+ + +KV K+ +S+ + + + +K+ + Q ++ R
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAE--GKAIKLAKDVASLSSQLQDTQELLQEETR 1329
Query: 2921 EK---QALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVR 2977
+K LRQ+E++ +LQD+ D+ + K++L + ++ +L + K
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1389
Query: 2978 WEESIQKFEEEISNIT 2993
EE ++F++EI N+T
Sbjct: 1390 LEEGKKRFQKEIENLT 1405
Score = 41.6 bits (96), Expect = 0.017
Identities = 78/363 (21%), Positives = 155/363 (42%), Gaps = 58/363 (15%)
Query: 2678 LSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVD 2737
L+++ ++ +A D+++ +L + +D + +DL + L++ E + ++L +
Sbjct: 1404 LTQQYEEKAAAYDKLEKTKNRLQQE---LDDLVVDLDN-QRQLVSNLEKKQRKFDQLLAE 1459
Query: 2738 QESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPA---LDAANKALDS----- 2789
+++ + + D A A+ + +ET+A++ R L+EAL A L+ NK L +
Sbjct: 1460 EKNISS-KYADERDRAEAEAREKETKALS--LARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 2790 -LDKADISE-IRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQ-----LLGDSNFLKRLL 2842
K D+ + + K + T ME + L D A + L + LK
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 2843 EYD-------KENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYS-RV 2894
E D E + Q+ +L +Y + ++ + A K + ++ ++L +
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
Query: 2895 VKVVEPKRQKLRAAQAEL--------------DITMATLREKQALLRQVEDQIQALQDEY 2940
+K E ++LR QA++ D AT +E + + +E + LQ++
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 2941 DKGVN-------EKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNIT 2993
EKE LA+ +A + + AL+DE+ R E I + EEE+
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSG-------RNALQDEKRRLEARIAQLEEELEEEQ 1749
Query: 2994 GNV 2996
GN+
Sbjct: 1750 GNM 1752
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 49.3 bits (116), Expect = 8e-05
Identities = 124/674 (18%), Positives = 275/674 (40%), Gaps = 84/674 (12%)
Query: 2359 GIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVK 2418
G DL+ LNK + + ++ + ++E+ +QD ++ ++ ++ K
Sbjct: 720 GKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDK 779
Query: 2419 LVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYN 2478
L F + + SR+ LL +G T LA YK E N
Sbjct: 780 L--FSEVVHKESRV---------QGLLEEIGKTKDD----LATTQSNYKSTDQEFQ---N 821
Query: 2479 YDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIV-VEEFLEDINNILNSGEVPNLFEKDELE 2537
+ + H D + YKM E++ M + +IV + + + ++ L + + ++ EL+
Sbjct: 822 FKTLHMDFEQKYKMVLEENERM-----NQEIVNLSKEAQKFDSSLGALKTELSYKTQELQ 876
Query: 2538 QVLAATRPRAKEVGISE---GNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPS 2594
+ + R E+ + NRD Q + R+K I + E ++ +
Sbjct: 877 EKTREVQERLNEMEQLKEQLENRDSTLQ---TVEREKTLITEKLQQTLEEVKTLTQEKDD 933
Query: 2595 LVNCCTIDWFVQWPREALLS-VSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYY 2653
L + +Q R+ L S + T +D E+L+ L + + +++++ +
Sbjct: 934 LKQ---LQESLQIERDQLKSDIHDTVNMNIDT-QEQLRNALESLKQHQE-TINTLKSKIS 988
Query: 2654 NELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDL 2713
E+ R + + M+ +KQ + A++ LT ++ N ++++ +
Sbjct: 989 EEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKN--TQTLTADVKDNEIIEQQRKIF 1046
Query: 2714 SALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDL 2773
S L+ + +++ ++E + ++E Q++ ++E+ EE + + D+ ++
Sbjct: 1047 S-----LIQEKNELQQMLESVIAEKE---QLKTDLKENIEMTIENQEELRLLGDELKKQQ 1098
Query: 2774 DEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLG 2833
+ + A K L + V K + + E LLN + + ++ +
Sbjct: 1099 EIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKIN 1158
Query: 2834 DSNFLKRLL---EYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDL 2890
+ LK L E E+++ + L QK N E+V+ ++K K + ++ +
Sbjct: 1159 EIENLKNELKNKELTLEHMETERLELAQKLNEN----YEEVKSITKERKVLKELQKSFET 1214
Query: 2891 -------YSRVVKV--VEPKRQ------KLRAAQAELDITMATLREKQALL--------- 2926
Y R ++ ++ K + L+ Q +D ++ EK A +
Sbjct: 1215 ERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKS 1274
Query: 2927 -RQVEDQIQALQDEYD-----KGVNE-KESLAKTMALTKARLVRAGKLTAALEDEQVRWE 2979
+++++I L +E + K V+E +E++ + LT+ + A +E E++R
Sbjct: 1275 HTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLN 1334
Query: 2980 ESIQKFEEEISNIT 2993
E Q+ +EEI ++T
Sbjct: 1335 EKFQESQEEIKSLT 1348
Score = 33.5 bits (75), Expect = 4.5
Identities = 57/324 (17%), Positives = 130/324 (40%), Gaps = 51/324 (15%)
Query: 2655 ELRRRYYTTPTSYLEL---INLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVD-KMK 2710
EL+ + T+Y ++ I LY S L K+K + +++ ++ + L+D K+
Sbjct: 650 ELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVP 709
Query: 2711 LDL----------SALEPVLLAKSEDVEALMEKLAVDQE------SADQVRNTVQEDEAT 2754
DL + L+ L + E+ EAL E++ + E +++R +Q+
Sbjct: 710 KDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQD---- 765
Query: 2755 AKVKAEETQAIADDAQRDLDEALPALDAANKALDSLDKA--DISEIRVFTKPPDLVMTVM 2812
K+EE I + + E + L+ + K D++ + K D
Sbjct: 766 ---KSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNF 822
Query: 2813 EAISILLNAKPDWPSAKQLLGDS--------NFLKRLLEYDKE--NIKPQILAKLQKYIN 2862
+ + + K K +L ++ N K ++D +K ++ K Q+
Sbjct: 823 KTLHMDFEQK-----YKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQE--- 874
Query: 2863 NPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREK 2922
+ EK +V + M ++ ++ VE ++ + + + TL ++
Sbjct: 875 ----LQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQE 930
Query: 2923 QALLRQVEDQIQALQDEYDKGVNE 2946
+ L+Q+++ +Q +D+ +++
Sbjct: 931 KDDLKQLQESLQIERDQLKSDIHD 954
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 150,939,974
Number of Sequences: 37866
Number of extensions: 6793927
Number of successful extensions: 20047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 178
Number of HSP's that attempted gapping in prelim test: 18449
Number of HSP's gapped (non-prelim): 1418
length of query: 4158
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4035
effective length of database: 13,590,000
effective search space: 54835650000
effective search space used: 54835650000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.