Guide to the Human Genome
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Search of human proteins with 194328738

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194328738 hypothetical protein LOC23247 [Homo sapiens]
         (1618 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194328738 hypothetical protein LOC23247 [Homo sapiens]            3300   0.0  
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa...    41   0.011
gi|178557736 microtubule-associated protein tau isoform 5 [Homo ...    41   0.011
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        40   0.014
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    40   0.024
gi|18379328 WW domain-containing adapter with a coiled-coil regi...    39   0.041
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    39   0.053
gi|150170670 piccolo isoform 2 [Homo sapiens]                          39   0.053
gi|150378539 piccolo isoform 1 [Homo sapiens]                          39   0.053
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    38   0.070
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    38   0.070
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]      38   0.070
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]       38   0.070
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       38   0.070
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    38   0.091
gi|18379332 WW domain-containing adapter with a coiled-coil regi...    38   0.091
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    37   0.12 
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    37   0.12 
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    37   0.12 
gi|119943102 CREB binding protein isoform b [Homo sapiens]             37   0.16 
gi|119943104 CREB binding protein isoform a [Homo sapiens]             37   0.16 
gi|54124343 hypothetical protein LOC387680 [Homo sapiens]              37   0.16 
gi|154090959 hypothetical protein LOC55747 [Homo sapiens]              37   0.16 
gi|239754474 PREDICTED: similar to mucin [Homo sapiens]                37   0.20 
gi|82830424 gon-4-like isoform a [Homo sapiens]                        37   0.20 
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 36   0.26 
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 36   0.26 
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  36   0.26 
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    36   0.26 
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    36   0.26 

>gi|194328738 hypothetical protein LOC23247 [Homo sapiens]
          Length = 1618

 Score = 3300 bits (8557), Expect = 0.0
 Identities = 1618/1618 (100%), Positives = 1618/1618 (100%)

Query: 1    MDGQTLRKAERSWSCSREKKEGYAKDMVTDFDEKHDEYLILLQQRNRILKHLKSKDPVQL 60
            MDGQTLRKAERSWSCSREKKEGYAKDMVTDFDEKHDEYLILLQQRNRILKHLKSKDPVQL
Sbjct: 1    MDGQTLRKAERSWSCSREKKEGYAKDMVTDFDEKHDEYLILLQQRNRILKHLKSKDPVQL 60

Query: 61   RLEHLEQGFSVYVNGANSELKSSPRKAIHSDFSRSASHTEGTHDYGRRTLFREAEEALRR 120
            RLEHLEQGFSVYVNGANSELKSSPRKAIHSDFSRSASHTEGTHDYGRRTLFREAEEALRR
Sbjct: 61   RLEHLEQGFSVYVNGANSELKSSPRKAIHSDFSRSASHTEGTHDYGRRTLFREAEEALRR 120

Query: 121  SSRTAPSKVQRRGWHQKSVQIRTEAGPRLHIEPPVDYSDDFELCGDVTLQANNTSEDRPQ 180
            SSRTAPSKVQRRGWHQKSVQIRTEAGPRLHIEPPVDYSDDFELCGDVTLQANNTSEDRPQ
Sbjct: 121  SSRTAPSKVQRRGWHQKSVQIRTEAGPRLHIEPPVDYSDDFELCGDVTLQANNTSEDRPQ 180

Query: 181  ELRRSLELSVNLQRKQKDCSSDEYDSIEEDILSEPEPEDPALVGHPRHDRPPSSGDWTQK 240
            ELRRSLELSVNLQRKQKDCSSDEYDSIEEDILSEPEPEDPALVGHPRHDRPPSSGDWTQK
Sbjct: 181  ELRRSLELSVNLQRKQKDCSSDEYDSIEEDILSEPEPEDPALVGHPRHDRPPSSGDWTQK 240

Query: 241  DVHGEQETEGRSSPGPDTLVVLEFNPASKSHKRERNLSAKRKDNAEVFVPTKPEPNLTPQ 300
            DVHGEQETEGRSSPGPDTLVVLEFNPASKSHKRERNLSAKRKDNAEVFVPTKPEPNLTPQ
Sbjct: 241  DVHGEQETEGRSSPGPDTLVVLEFNPASKSHKRERNLSAKRKDNAEVFVPTKPEPNLTPQ 300

Query: 301  APAVFPDQERMCSRPGSRRERPLSATRKTLCEAEYPEEDASAVLQAIQVENAALQRALLS 360
            APAVFPDQERMCSRPGSRRERPLSATRKTLCEAEYPEEDASAVLQAIQVENAALQRALLS
Sbjct: 301  APAVFPDQERMCSRPGSRRERPLSATRKTLCEAEYPEEDASAVLQAIQVENAALQRALLS 360

Query: 361  RKAEQPASPLQDAEGPPAKPWTSLLEEKEETLELLPITTATTTQEPAGAAGGARAINQAM 420
            RKAEQPASPLQDAEGPPAKPWTSLLEEKEETLELLPITTATTTQEPAGAAGGARAINQAM
Sbjct: 361  RKAEQPASPLQDAEGPPAKPWTSLLEEKEETLELLPITTATTTQEPAGAAGGARAINQAM 420

Query: 421  DRIGLLGSRQQQKLLKVLQAVESDSAHLGRVVSPTKEQVSDTEDKQRMRADEIKDAIYVT 480
            DRIGLLGSRQQQKLLKVLQAVESDSAHLGRVVSPTKEQVSDTEDKQRMRADEIKDAIYVT
Sbjct: 421  DRIGLLGSRQQQKLLKVLQAVESDSAHLGRVVSPTKEQVSDTEDKQRMRADEIKDAIYVT 480

Query: 481  MEILSNWGNSWWVGLTEVEFFDLNDTKLYVSPHDVDIRNTATPGELGRLVNRNLAGKKDS 540
            MEILSNWGNSWWVGLTEVEFFDLNDTKLYVSPHDVDIRNTATPGELGRLVNRNLAGKKDS
Sbjct: 481  MEILSNWGNSWWVGLTEVEFFDLNDTKLYVSPHDVDIRNTATPGELGRLVNRNLAGKKDS 540

Query: 541  SPWTCPFHPPLQLFFVIRNTRQLGDFHLAKIKVRNYWTADGDLDIGAKNVKLYVNRNLIF 600
            SPWTCPFHPPLQLFFVIRNTRQLGDFHLAKIKVRNYWTADGDLDIGAKNVKLYVNRNLIF
Sbjct: 541  SPWTCPFHPPLQLFFVIRNTRQLGDFHLAKIKVRNYWTADGDLDIGAKNVKLYVNRNLIF 600

Query: 601  NGKLDKGDREAPADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGASGDKELGLGCS 660
            NGKLDKGDREAPADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGASGDKELGLGCS
Sbjct: 601  NGKLDKGDREAPADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGASGDKELGLGCS 660

Query: 661  PPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPP 720
            PPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPP
Sbjct: 661  PPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPP 720

Query: 721  VKCPPVHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDRKQGGRKPKPLWLSPEK 780
            VKCPPVHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDRKQGGRKPKPLWLSPEK
Sbjct: 721  VKCPPVHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDRKQGGRKPKPLWLSPEK 780

Query: 781  PLAWKGRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKERPQRATTKVHSDDSDI 840
            PLAWKGRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKERPQRATTKVHSDDSDI
Sbjct: 781  PLAWKGRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKERPQRATTKVHSDDSDI 840

Query: 841  FNQPPNRERPASGRRGSRKDAGSSSHGDDQPASREDTWSSRTPSRSRWRSEQEHTLHESW 900
            FNQPPNRERPASGRRGSRKDAGSSSHGDDQPASREDTWSSRTPSRSRWRSEQEHTLHESW
Sbjct: 841  FNQPPNRERPASGRRGSRKDAGSSSHGDDQPASREDTWSSRTPSRSRWRSEQEHTLHESW 900

Query: 901  SSLSAFDRSHRGRISNTELPGDILDELLQQKSSRHSDLPPSKKGEQPGLSRGQDGYSGET 960
            SSLSAFDRSHRGRISNTELPGDILDELLQQKSSRHSDLPPSKKGEQPGLSRGQDGYSGET
Sbjct: 901  SSLSAFDRSHRGRISNTELPGDILDELLQQKSSRHSDLPPSKKGEQPGLSRGQDGYSGET 960

Query: 961  DAGGDFKIPVLPYGQRLVIDIKSTWGDRHYVGLNGIEIFSSKGEPVQISNIKADPPDINI 1020
            DAGGDFKIPVLPYGQRLVIDIKSTWGDRHYVGLNGIEIFSSKGEPVQISNIKADPPDINI
Sbjct: 961  DAGGDFKIPVLPYGQRLVIDIKSTWGDRHYVGLNGIEIFSSKGEPVQISNIKADPPDINI 1020

Query: 1021 LPAYGKDPRVVTNLIDGVNRTQDDMHVWLAPFTRGRSHSITIDFTHPCHVALIRIWNYNK 1080
            LPAYGKDPRVVTNLIDGVNRTQDDMHVWLAPFTRGRSHSITIDFTHPCHVALIRIWNYNK
Sbjct: 1021 LPAYGKDPRVVTNLIDGVNRTQDDMHVWLAPFTRGRSHSITIDFTHPCHVALIRIWNYNK 1080

Query: 1081 SRIHSFRGVKDITMLLDTQCIFEGEIAKASGTLAGAPEHFGDTILFTTDDDILEAIFYSD 1140
            SRIHSFRGVKDITMLLDTQCIFEGEIAKASGTLAGAPEHFGDTILFTTDDDILEAIFYSD
Sbjct: 1081 SRIHSFRGVKDITMLLDTQCIFEGEIAKASGTLAGAPEHFGDTILFTTDDDILEAIFYSD 1140

Query: 1141 EMFDLDVGSLDSLQDEEAMRRPSTADGEGDERPFTQAGLGADERIPELELPSSSPVPQVT 1200
            EMFDLDVGSLDSLQDEEAMRRPSTADGEGDERPFTQAGLGADERIPELELPSSSPVPQVT
Sbjct: 1141 EMFDLDVGSLDSLQDEEAMRRPSTADGEGDERPFTQAGLGADERIPELELPSSSPVPQVT 1200

Query: 1201 TPEPGIYHGICLQLNFTASWGDLHYLGLTGLEVVGKEGQALPIHLHQISASPRDLNELPE 1260
            TPEPGIYHGICLQLNFTASWGDLHYLGLTGLEVVGKEGQALPIHLHQISASPRDLNELPE
Sbjct: 1201 TPEPGIYHGICLQLNFTASWGDLHYLGLTGLEVVGKEGQALPIHLHQISASPRDLNELPE 1260

Query: 1261 YSDDSRALDKLIDGTNITMEDEHMWLIPFSPGLDHVVTIRLDRAESIAGLRFWNYNKSPE 1320
            YSDDSRALDKLIDGTNITMEDEHMWLIPFSPGLDHVVTIRLDRAESIAGLRFWNYNKSPE
Sbjct: 1261 YSDDSRALDKLIDGTNITMEDEHMWLIPFSPGLDHVVTIRLDRAESIAGLRFWNYNKSPE 1320

Query: 1321 DTYRGAKIVHVSLDGLCVSPPEGFLIRKGPGNCHFDFAQEILFVDYLRAQLLPQPARRLD 1380
            DTYRGAKIVHVSLDGLCVSPPEGFLIRKGPGNCHFDFAQEILFVDYLRAQLLPQPARRLD
Sbjct: 1321 DTYRGAKIVHVSLDGLCVSPPEGFLIRKGPGNCHFDFAQEILFVDYLRAQLLPQPARRLD 1380

Query: 1381 MRSLECASMDYEAPLMPCGFIFQFQLLTSWGDPYYIGLTGLELYDERGEKIPLSENNIAA 1440
            MRSLECASMDYEAPLMPCGFIFQFQLLTSWGDPYYIGLTGLELYDERGEKIPLSENNIAA
Sbjct: 1381 MRSLECASMDYEAPLMPCGFIFQFQLLTSWGDPYYIGLTGLELYDERGEKIPLSENNIAA 1440

Query: 1441 FPDSVNSLEGVGGDVRTPDKLIDQVNDTSDGRHMWLAPILPGLVNRVYVIFDLPTTVSMI 1500
            FPDSVNSLEGVGGDVRTPDKLIDQVNDTSDGRHMWLAPILPGLVNRVYVIFDLPTTVSMI
Sbjct: 1441 FPDSVNSLEGVGGDVRTPDKLIDQVNDTSDGRHMWLAPILPGLVNRVYVIFDLPTTVSMI 1500

Query: 1501 KLWNYAKTPHRGVKEFGLLVDDLLVYNGILAMVSHLVGGILPTCEPTVPYHTILFTEDRD 1560
            KLWNYAKTPHRGVKEFGLLVDDLLVYNGILAMVSHLVGGILPTCEPTVPYHTILFTEDRD
Sbjct: 1501 KLWNYAKTPHRGVKEFGLLVDDLLVYNGILAMVSHLVGGILPTCEPTVPYHTILFTEDRD 1560

Query: 1561 IRHQEKHTTISNQAEDQDVQMMNENQIITNAKRKQSVVDPALRPKTCISEKETRRRRC 1618
            IRHQEKHTTISNQAEDQDVQMMNENQIITNAKRKQSVVDPALRPKTCISEKETRRRRC
Sbjct: 1561 IRHQEKHTTISNQAEDQDVQMMNENQIITNAKRKQSVVDPALRPKTCISEKETRRRRC 1618


>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
           sapiens]
          Length = 441

 Score = 40.8 bits (94), Expect = 0.011
 Identities = 64/279 (22%), Positives = 100/279 (35%), Gaps = 38/279 (13%)

Query: 580 DGDLDIGAKNVKLYVNRNLIFNGKLDKGD-----REAPADHSILVDQKNEKSEQLEEAMN 634
           +GD D G K   L        +G  + G      +  P    +     +E +   + A  
Sbjct: 36  EGDTDAGLKESPLQTPTE---DGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ 92

Query: 635 AHSEESKGTHEMAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQ 694
            H+E  +GT         +E G+G +P  E  A   ++ Q  +  K K+ T         
Sbjct: 93  PHTEIPEGTTA-------EEAGIGDTPSLEDEAAGHVT-QARMVSKSKDGTGSDDKKAKG 144

Query: 695 LEEYLRLS----AVPTSMGDMPSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPG- 749
            +   +++    A P   G    A AT  P K PP  + P    +      R     PG 
Sbjct: 145 ADGKTKIATPRGAAPP--GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGS 202

Query: 750 --------KTPSWLQPSPTGKDRKQGGRKPKPLWLSPEKPLAWKGRLPSDDV--IGEGPG 799
                   +TPS   P PT + +K    +  P   S  K       +P  D+  +    G
Sbjct: 203 PGTPGSRSRTPSLPTP-PTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIG 261

Query: 800 ETEARDKGLRHEPGWGTSRSVNTKERPQRATTKVHSDDS 838
            TE     L+H+PG G  + +N K       +K  S D+
Sbjct: 262 STE----NLKHQPGGGKVQIINKKLDLSNVQSKCGSKDN 296


>gi|178557736 microtubule-associated protein tau isoform 5 [Homo
           sapiens]
          Length = 412

 Score = 40.8 bits (94), Expect = 0.011
 Identities = 61/261 (23%), Positives = 97/261 (37%), Gaps = 33/261 (12%)

Query: 602 GKLDKGDREAPADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGASGD--------- 652
           G    GDR+    +++  DQ+ +    L+E+      E  G+ E    + D         
Sbjct: 16  GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTED-GSEEPGSETSDAKSTPTAEA 74

Query: 653 KELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLS----AVPTSM 708
           +E G+G +P  E  A   ++ Q  +  K K+ T          +   +++    A P   
Sbjct: 75  EEAGIGDTPSLEDEAAGHVT-QARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP-- 131

Query: 709 GDMPSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPG---------KTPSWLQPSP 759
           G    A AT  P K PP  + P    +      R     PG         +TPS   P P
Sbjct: 132 GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP-P 190

Query: 760 TGKDRKQGGRKPKPLWLSPEKPLAWKGRLPSDDV--IGEGPGETEARDKGLRHEPGWGTS 817
           T + +K    +  P   S  K       +P  D+  +    G TE     L+H+PG G  
Sbjct: 191 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE----NLKHQPGGGKV 246

Query: 818 RSVNTKERPQRATTKVHSDDS 838
           + +N K       +K  S D+
Sbjct: 247 QIINKKLDLSNVQSKCGSKDN 267


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 40.4 bits (93), Expect = 0.014
 Identities = 74/316 (23%), Positives = 114/316 (36%), Gaps = 77/316 (24%)

Query: 650  SGDKELGLGCSPPAETLAD-----------AKLSSQGNVSGKRKNSTNCRKDSLSQLEEY 698
            SG    G G SP   +  +           A+  S+ +   K K+ T  R+ S     E 
Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL 1697

Query: 699  LRLSAVPTSMGDMPSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPGKTPSWLQPS 758
             R + +        S+P T    + PP H                      ++PS   P 
Sbjct: 1698 TRKARLSRRSRSASSSPETRS--RTPPRHR---------------------RSPSVSSPE 1734

Query: 759  PTGKDRKQGGRKPKPLWLSPE-KPLAWKGRLPSDDVIGEGPGETEARDKGLRHEPGWGTS 817
            P  K R    R+      SP  K  + +GR PS             + +GL+       S
Sbjct: 1735 PAEKSRSSRRRRSAS---SPRTKTTSRRGRSPSP------------KPRGLQR------S 1773

Query: 818  RSVNTKERPQRATTKVHSDDSDIFNQPPNRERPASGRRGSRKDAGSSSHGDDQPASREDT 877
            RS + +E+ +    +  S  S   ++   R+R  S  R +R+  G S +    PA +E +
Sbjct: 1774 RSRSRREKTRTTRRRDRSGSSQSTSR--RRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831

Query: 878  WS--------SRTPSRSRWRSEQEHTLHESW--SSLSAFDRSHRGRISNTELPGDILDEL 927
             +        SRTP  SR RS +  T    W  S   A   +HR   S T         L
Sbjct: 1832 RTSSRRRRGRSRTPPTSRKRS-RSRTSPAPWKRSRSRASPATHRRSRSRT--------PL 1882

Query: 928  LQQKSSRHSDLPPSKK 943
            + ++ SR    P S++
Sbjct: 1883 ISRRRSRSRTSPVSRR 1898



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 43/175 (24%), Positives = 62/175 (35%), Gaps = 16/175 (9%)

Query: 795 GEGPGETEARDKGLRHEPGWGTSRSVNTKERPQRATTKVHSDDSDIFNQPPNRERPASGR 854
           G     T AR +     P    SRS +   R  R+ ++  +      ++ P R     GR
Sbjct: 613 GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR----GR 668

Query: 855 RGSRKDAGSSSHGDDQPASREDTWSSRTPSRSRWRS--------EQEHTLHESWSSLSAF 906
             SR  A  S     +  +R     SRTP R R RS            T      S S+ 
Sbjct: 669 SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728

Query: 907 DRSHRGRISNTELPGDILDEL----LQQKSSRHSDLPPSKKGEQPGLSRGQDGYS 957
           +R ++ R S      +   E+    +  + SR    P SK   +  L R   G S
Sbjct: 729 ERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 64/316 (20%), Positives = 107/316 (33%), Gaps = 39/316 (12%)

Query: 78   SELKSSPRKAIHSDFSRSASHTEGTHDYGRRTLFREAEEALRRSS-------RTAPSKVQ 130
            SE  SSP         R  S +  + +   + L  + E +   SS       RT   +  
Sbjct: 1478 SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537

Query: 131  RRGWHQKSVQIRTEAGPRLHIEPPVDYSDDFELCGDVTLQANNTSEDRPQELRRSLELSV 190
            R G  Q+ + ++  A P+   E   D S D +      L+  + S   P+   +S    +
Sbjct: 1538 RSGSSQE-LDVKPSASPQERSES--DSSPDSKAKTRTPLRQRSRSGSSPEVDSKS---RL 1591

Query: 191  NLQRKQKDCSSDEYDS------IEEDILSEPEPEDPALVGHPRHDRPPSSGDWTQKDVHG 244
            + +R +   S +  D        +    S PEP+ PA    PR  R  SS         G
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651

Query: 245  EQETEGRSSPGPDTLVVLEFNPASKSHKRERNLSAKRKDNAEVFVPTKPEPNLTPQAPAV 304
               TE      P +      + +S   K +     +R+        ++  P LT +A   
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS-------SRSSPELTRKARL- 1703

Query: 305  FPDQERMCSRPGSRRERPLSATRKTLCEAEYPEEDASAVLQAIQVENAALQRALLSRKAE 364
                        SRR R  S++ +T          + +V      E +   R   S  + 
Sbjct: 1704 ------------SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSP 1751

Query: 365  QPASPLQDAEGPPAKP 380
            +  +  +    P  KP
Sbjct: 1752 RTKTTSRRGRSPSPKP 1767



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 37/145 (25%), Positives = 57/145 (39%), Gaps = 10/145 (6%)

Query: 755 LQPSPTGKDRKQG-GRKPKPLWLSPEKPLAWKGRLPSDDVIGEGPGETEA-RDKGLRHEP 812
           +  SPT K+R  G  ++ K    +P + +  + R P+    G     T   R       P
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRRMG-RSRSPATAKRGRSRSRTPTKRGHSRSRSP 511

Query: 813 GWGTSRSVNT--KERPQRATTKVHSDDSDIFNQPPN---RERPASGRRGSRKDAGSSSHG 867
            W  SRS     + R  +   +  S     +++  N   R R  S RRG       ++ G
Sbjct: 512 QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRG 571

Query: 868 DDQPAS--REDTWSSRTPSRSRWRS 890
             +  +  R     SRTP+R R RS
Sbjct: 572 RSRSRTPARRGRSRSRTPARRRSRS 596



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 66/334 (19%), Positives = 122/334 (36%), Gaps = 39/334 (11%)

Query: 119 RRSSRTAPSKVQRRGWHQKSVQIRTEAGPRLHIEPPVDYSDDFELCGDVTLQANNTSEDR 178
           RRS  ++P + +++   +K  +  +E+  R H  P              T ++   S+D+
Sbjct: 198 RRSESSSPRRERKKSSKKKKHRSESESKKRKHRSP--------------TPKSKRKSKDK 243

Query: 179 PQELRRSLELSVNLQRKQKDCSSDEYDSIE----EDILSEPEPEDPALVGHPRHDRPPSS 234
            ++  RS   +   +R  +  S+D   S +        +  +    AL G       P+S
Sbjct: 244 KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG---RSPSPAS 300

Query: 235 GDWTQKDV-HGEQETEGRSSP-GPDTLVVLEFNPASKSHKRERNLSAKRKDNAEVFVPTK 292
           G   + D    E  T     P  P+T      +P     K ++  SA R   +     T 
Sbjct: 301 GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360

Query: 293 PEPNL-----------TPQAPAVFPDQERMCSRPGS---RRERPLSATRKTLCEAEYPEE 338
           PEP             +PQ  A  P  +   + P      R+R    + + L ++   E 
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420

Query: 339 DASAVLQAIQVENAALQRALLSRKAEQPASPLQDAEGPPAKPWTSLLEEKEETLELLPIT 398
              +  Q  +V   A       + A  P S  + +  P +K  +    +++++    P  
Sbjct: 421 SPPSP-QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSR 479

Query: 399 TATTTQEPAGAAGGARAINQAMDRIGLLGSRQQQ 432
               ++ PA A  G R+ ++   + G   SR  Q
Sbjct: 480 RMGRSRSPATAKRG-RSRSRTPTKRGHSRSRSPQ 512


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 39.7 bits (91), Expect = 0.024
 Identities = 76/330 (23%), Positives = 127/330 (38%), Gaps = 60/330 (18%)

Query: 638  EESKGTHEMAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEE 697
            EE     ++   S +K++        + +   + SS+ ++SGK    T       S L++
Sbjct: 1027 EEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVS-----SDLDQ 1081

Query: 698  YLRLSAVPTSMGDMPSAPATSPPVKCPP--VHEEPSLIQQLENLM----GRKICEPPGKT 751
            + +  +    +   P+A  T   V C     H E S+   +E+++      +IC P   +
Sbjct: 1082 FTKDDS---KLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSS 1138

Query: 752  PSWLQP-SPTGKDR----------KQGGRKPKPLW--------LSPEKPLAWKGRLPSDD 792
            P+ ++  SP G  R          KQ      P          +S  K L   G+  S  
Sbjct: 1139 PAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSS 1198

Query: 793  V----IGEGPGETEARDKGLRH--EPGWGTSRSVNTKERPQRATT------------KVH 834
                  GE  G+ E  +K   +  +  W   + V     P  AT+            ++ 
Sbjct: 1199 ASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMK 1258

Query: 835  SDDSDIFNQPPNRERPAS-------GRRGSRKDAGSSSHGDDQPASREDTWSSRTPSRSR 887
                 I  +  N+ RP S         R +R+     S  D+Q  SR+D   SR+PSRSR
Sbjct: 1259 PQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSR 1318

Query: 888  WRSEQEHTLHESWSSLSAFDRSHRGRISNT 917
             +SE + + H + S   +  RS R R S +
Sbjct: 1319 SKSETK-SRHRTRSVSYSHSRS-RSRSSTS 1346



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 51/221 (23%), Positives = 90/221 (40%), Gaps = 16/221 (7%)

Query: 77  NSELKSSPRKAIHSDFSRSASHTEGTHDYGRRTLFREAEEALRRS-SRTAPSKVQRRGWH 135
           +S   S  + + HS  SRS+S+T  + D GRR   R      + S S    S    +  H
Sbjct: 723 SSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLH 782

Query: 136 QKSVQIRTEAG-PRLHIE--PPVDYSDDFELCGDVTLQANNTSEDRPQELRRSLELSVNL 192
            K V+ R  +   R + E    +DYS D E     ++QA  +++++  E +  +E + N 
Sbjct: 783 SKYVKGRDRSSCVRKYSESRSSLDYSSDSE---QSSVQATQSAQEK--EKQGQMERTHNK 837

Query: 193 QRKQKDCSSDEYDSIEEDILSEPEPEDPALVGHPRHDRPPSSGDWTQKDVHGEQETEGRS 252
           Q K +    ++  S  E   S+       L  H R+   P   ++       E  +E   
Sbjct: 838 QEKNR--GEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDV 895

Query: 253 SPGPDTLVVLEFNPASKSHKRERNLSAKRKDNAEVFVPTKP 293
           +         + +P+S   + E   S    + +E+ +  KP
Sbjct: 896 TKNSKN----DSHPSSDKEEGEAT-SDSESEVSEIHIKVKP 931



 Score = 31.6 bits (70), Expect = 6.5
 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 3/95 (3%)

Query: 820  VNTKERPQRATT--KVHSDDSDIFNQPPNRERPASGRRGSRKDAGSS-SHGDDQPASRED 876
            +N + R Q +++  +  S D D  ++ P+R R  S  +   +    S SH   +  S   
Sbjct: 1287 LNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTS 1346

Query: 877  TWSSRTPSRSRWRSEQEHTLHESWSSLSAFDRSHR 911
            ++ SR+ SRSR R         S SS     +SHR
Sbjct: 1347 SYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHR 1381


>gi|18379328 WW domain-containing adapter with a coiled-coil region
           isoform 1 [Homo sapiens]
          Length = 647

 Score = 38.9 bits (89), Expect = 0.041
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 662 PAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPPV 721
           P  ++   K   + + SG +  S +C   S S        SA PTS   +P +P    P+
Sbjct: 294 PTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPI 353

Query: 722 KCPPVHEEPSLIQQL 736
             PP+ ++P+L++QL
Sbjct: 354 --PPLLQDPNLLRQL 366


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo
            sapiens]
          Length = 1125

 Score = 38.5 bits (88), Expect = 0.053
 Identities = 78/348 (22%), Positives = 115/348 (33%), Gaps = 60/348 (17%)

Query: 661  PPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPP 720
            PP  T     +S    VSG R N+ +   DS+         +  P +  ++P+ P T P 
Sbjct: 754  PPPHT---PPISIPNLVSGARGNAES--GDSVKMYGS----AVPPAAPTNLPTPPVTQPV 804

Query: 721  VKCPPVHEEPSLIQQLE----NLMGRK-----ICEPPGKTPSWLQ------PSPTGKDRK 765
                     P  +  L+     L+G +     +  PPG  P  LQ      P P      
Sbjct: 805  SLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMM 864

Query: 766  QGGRKPKPLWLSPEKPLAWKGRLPSDDVI------------GEGPGETEARDKGLR---- 809
              G  P P   +   P   KG  P                 G GPG  E RD   +    
Sbjct: 865  HRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQ 924

Query: 810  ----------HEPGWGTSRSVNTKERP---QRATTKVHSDDSDIFNQPPNRERPASGRRG 856
                       +P     +     ++P   Q+   +  +D+   FN   ++ER      G
Sbjct: 925  PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFG 984

Query: 857  SRKDAGSSSHG---DDQPASRED--TWSSRTPSRSRWRSEQEHTLHESWSSLSAFD-RSH 910
            +R +     +G   DD+  S  D   W  R+P R R R  +E     S       D R  
Sbjct: 985  NRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDR 1044

Query: 911  RGRISNTELPGDILDELLQQKSSRHSDLPP-SKKGEQPGLSRGQDGYS 957
              R    E  G    E+  +     +  PP S+ G     S  + G S
Sbjct: 1045 ESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKGVS 1092


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 38.5 bits (88), Expect = 0.053
 Identities = 72/309 (23%), Positives = 113/309 (36%), Gaps = 40/309 (12%)

Query: 602 GKLDKGDREAP-ADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGASGDKELGLGCS 660
           GK  +G  + P  DH+ L  Q++    Q ++A     E  K +         ++   G  
Sbjct: 255 GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG-K 313

Query: 661 PPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPP 720
           PPA+     K  SQ   +      +   K  L+Q    ++    P      P+ P    P
Sbjct: 314 PPAQQPGHEK--SQPGPAKPPAQPSGLTKP-LAQQPGTVKPPVQPPGTTKPPAQPLG--P 368

Query: 721 VKCPPVHEEPSLIQQLENLMGRKICEPP--GKTPSWLQPSPTGKDRKQGGRKPKPLWLSP 778
            K PP  +  S     E    + + +PP  GKTP+  QP P     +Q G  PKPL   P
Sbjct: 369 AK-PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA-QQPGPAKPPTQQVG-TPKPLAQQP 425

Query: 779 EKPLAWK--------------GRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKE 824
                 K              G++P+      GPG+T A+  G    P      +    +
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQA---GPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482

Query: 825 RP--------QRATTKVHSDDSDIFNQPPNRERPASGRRGSRKDAGSSSHGDDQPASRED 876
           +P        Q  + K  S        PP +  PA   + S +  GS+     QP S + 
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA---KPSPQQPGSTKPPSQQPGSAKP 539

Query: 877 TWSSRTPSR 885
           +    +P++
Sbjct: 540 SAQQPSPAK 548


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 38.5 bits (88), Expect = 0.053
 Identities = 72/309 (23%), Positives = 113/309 (36%), Gaps = 40/309 (12%)

Query: 602 GKLDKGDREAP-ADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGASGDKELGLGCS 660
           GK  +G  + P  DH+ L  Q++    Q ++A     E  K +         ++   G  
Sbjct: 255 GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG-K 313

Query: 661 PPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPP 720
           PPA+     K  SQ   +      +   K  L+Q    ++    P      P+ P    P
Sbjct: 314 PPAQQPGHEK--SQPGPAKPPAQPSGLTKP-LAQQPGTVKPPVQPPGTTKPPAQPLG--P 368

Query: 721 VKCPPVHEEPSLIQQLENLMGRKICEPP--GKTPSWLQPSPTGKDRKQGGRKPKPLWLSP 778
            K PP  +  S     E    + + +PP  GKTP+  QP P     +Q G  PKPL   P
Sbjct: 369 AK-PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA-QQPGPAKPPTQQVG-TPKPLAQQP 425

Query: 779 EKPLAWK--------------GRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKE 824
                 K              G++P+      GPG+T A+  G    P      +    +
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQA---GPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482

Query: 825 RP--------QRATTKVHSDDSDIFNQPPNRERPASGRRGSRKDAGSSSHGDDQPASRED 876
           +P        Q  + K  S        PP +  PA   + S +  GS+     QP S + 
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA---KPSPQQPGSTKPPSQQPGSAKP 539

Query: 877 TWSSRTPSR 885
           +    +P++
Sbjct: 540 SAQQPSPAK 548


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo
            sapiens]
          Length = 1132

 Score = 38.1 bits (87), Expect = 0.070
 Identities = 80/363 (22%), Positives = 119/363 (32%), Gaps = 67/363 (18%)

Query: 646  MAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVP 705
            +AG + D    L    P  T+          VSG R N+ +   DS+         +  P
Sbjct: 753  IAGINEDTTKDLSIGNPIPTV----------VSGARGNAES--GDSVKMYGS----AVPP 796

Query: 706  TSMGDMPSAPATSPPVKCPPVHEEPSLIQQLE----NLMGRK-----ICEPPGKTPSWLQ 756
             +  ++P+ P T P          P  +  L+     L+G +     +  PPG  P  LQ
Sbjct: 797  AAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQ 856

Query: 757  ------PSPTGKDRKQGGRKPKPLWLSPEKPLAWKGRLPSDDVI------------GEGP 798
                  P P        G  P P   +   P   KG  P                 G GP
Sbjct: 857  RFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGP 916

Query: 799  GETEARDKGLR--------------HEPGWGTSRSVNTKERP---QRATTKVHSDDSDIF 841
            G  E RD   +               +P     +     ++P   Q+   +  +D+   F
Sbjct: 917  GGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQF 976

Query: 842  NQPPNRERPASGRRGSRKDAGSSSHG---DDQPASRED--TWSSRTPSRSRWRSEQEHTL 896
            N   ++ER      G+R +     +G   DD+  S  D   W  R+P R R R  +E   
Sbjct: 977  NSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNR 1036

Query: 897  HESWSSLSAFD-RSHRGRISNTELPGDILDELLQQKSSRHSDLPP-SKKGEQPGLSRGQD 954
              S       D R    R    E  G    E+  +     +  PP S+ G     S  + 
Sbjct: 1037 RSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEK 1096

Query: 955  GYS 957
            G S
Sbjct: 1097 GVS 1099


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo
            sapiens]
          Length = 1147

 Score = 38.1 bits (87), Expect = 0.070
 Identities = 80/363 (22%), Positives = 119/363 (32%), Gaps = 67/363 (18%)

Query: 646  MAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVP 705
            +AG + D    L    P  T+          VSG R N+ +   DS+         +  P
Sbjct: 768  IAGINEDTTKDLSIGNPIPTV----------VSGARGNAES--GDSVKMYGS----AVPP 811

Query: 706  TSMGDMPSAPATSPPVKCPPVHEEPSLIQQLE----NLMGRK-----ICEPPGKTPSWLQ 756
             +  ++P+ P T P          P  +  L+     L+G +     +  PPG  P  LQ
Sbjct: 812  AAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQ 871

Query: 757  ------PSPTGKDRKQGGRKPKPLWLSPEKPLAWKGRLPSDDVI------------GEGP 798
                  P P        G  P P   +   P   KG  P                 G GP
Sbjct: 872  RFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGP 931

Query: 799  GETEARDKGLR--------------HEPGWGTSRSVNTKERP---QRATTKVHSDDSDIF 841
            G  E RD   +               +P     +     ++P   Q+   +  +D+   F
Sbjct: 932  GGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQF 991

Query: 842  NQPPNRERPASGRRGSRKDAGSSSHG---DDQPASRED--TWSSRTPSRSRWRSEQEHTL 896
            N   ++ER      G+R +     +G   DD+  S  D   W  R+P R R R  +E   
Sbjct: 992  NSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNR 1051

Query: 897  HESWSSLSAFD-RSHRGRISNTELPGDILDELLQQKSSRHSDLPP-SKKGEQPGLSRGQD 954
              S       D R    R    E  G    E+  +     +  PP S+ G     S  + 
Sbjct: 1052 RSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEK 1111

Query: 955  GYS 957
            G S
Sbjct: 1112 GVS 1114


>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
          Length = 733

 Score = 38.1 bits (87), Expect = 0.070
 Identities = 48/182 (26%), Positives = 67/182 (36%), Gaps = 31/182 (17%)

Query: 705 PTSMGDMPSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDR 764
           P +  ++P  P  SPP   P  ++EP L   L +L       PP       + +P     
Sbjct: 258 PLAERELPPRP-DSPPSAGPAAYKEPPLA--LPSL-------PPLPFQKLEEAAPPSDPF 307

Query: 765 KQGGRKPKPLWLSPEKPLAWKGRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKE 824
           + G   P      PE P    GR          P       + ++HEPG G+      +E
Sbjct: 308 RGGSGSP-----GPEPP----GR----------PDGPSLLYRWMKHEPGLGSYGDELGRE 348

Query: 825 R--PQRATTKVHSDDSDIFNQPPNRERPASGRRGSRKDAGSSSHGDDQPASREDTWSSRT 882
           R  P     +   D +     PP    P     GS    G+   GDD  +S E+T SS  
Sbjct: 349 RGSPSERCEERGGDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSED 408

Query: 883 PS 884
           PS
Sbjct: 409 PS 410


>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
          Length = 714

 Score = 38.1 bits (87), Expect = 0.070
 Identities = 48/182 (26%), Positives = 67/182 (36%), Gaps = 31/182 (17%)

Query: 705 PTSMGDMPSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDR 764
           P +  ++P  P  SPP   P  ++EP L   L +L       PP       + +P     
Sbjct: 239 PLAERELPPRP-DSPPSAGPAAYKEPPLA--LPSL-------PPLPFQKLEEAAPPSDPF 288

Query: 765 KQGGRKPKPLWLSPEKPLAWKGRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKE 824
           + G   P      PE P    GR          P       + ++HEPG G+      +E
Sbjct: 289 RGGSGSP-----GPEPP----GR----------PDGPSLLYRWMKHEPGLGSYGDELGRE 329

Query: 825 R--PQRATTKVHSDDSDIFNQPPNRERPASGRRGSRKDAGSSSHGDDQPASREDTWSSRT 882
           R  P     +   D +     PP    P     GS    G+   GDD  +S E+T SS  
Sbjct: 330 RGSPSERCEERGGDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSED 389

Query: 883 PS 884
           PS
Sbjct: 390 PS 391


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 38.1 bits (87), Expect = 0.070
 Identities = 58/295 (19%), Positives = 106/295 (35%), Gaps = 48/295 (16%)

Query: 153  PPVDYSDDFELCGDVTLQANNTSEDRPQELRRSL------------ELSVNLQRKQKDCS 200
            P +D  D   +  D  L + N+++D+ Q+ ++              E  +N Q  ++D  
Sbjct: 4800 PGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYD 4859

Query: 201  SDEYDSIEEDILSEPEPEDPALVGHPRHDRPPSSGDWTQKDVHGEQETEGRSSPGPDTLV 260
             +E D    +    PEPE   L         P   +   +D +G ++T+       + L 
Sbjct: 4860 ENEVDPYHGNQEKVPEPEALDL---------PDDLNLDSEDKNGGEDTDNEEGEEENPLE 4910

Query: 261  VLEFNPASKSHKRERNLSAKRKDNAEVFVPTKPEPNLTPQAPAVFPDQERMCSRPGSRRE 320
            + E  P    H+ E     +   N           + +PQ P   P ++    +     E
Sbjct: 4911 IKE-KPEEAGHEAEERGETETDQN----------ESQSPQEPEEGPSED---DKAEGEEE 4956

Query: 321  RPLSATRKTLCEAEYPEEDASAVLQAI-QVENAALQRALLSRKAEQPASPLQDAEGPPAK 379
                A  +    A++PEE +    Q++ + +  A +    +  A+Q   P ++ E     
Sbjct: 4957 MDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEE----- 5011

Query: 380  PWTSLLEEKEETLELLPITTATTTQEPAGAAGGARAIN-QAMDRIGLLGSRQQQK 433
                   E  +T E +P           G  G     N QAM+  G    ++Q K
Sbjct: 5012 ------REDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK 5060


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 37.7 bits (86), Expect = 0.091
 Identities = 90/470 (19%), Positives = 161/470 (34%), Gaps = 44/470 (9%)

Query: 2   DGQTLRKAERSWSCSREKKEGYAKDMVTDFDEKHDEYLILLQQRNRILKHLKSKDPVQLR 61
           D +  RK ER  S  R+ +     +     +E+ D+       R R  ++LK+++  +  
Sbjct: 217 DDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEE 276

Query: 62  LEHLEQGFSVYVNGANSELKSSPRKAIHSDFSRSASHTEGTHDYGRRTLFREAE-EALRR 120
            E  E       +    + + +P      +        +       R   R  E E L R
Sbjct: 277 EEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLER 336

Query: 121 SSRTAPSKVQRRGWHQKSVQIRTEAGPRLHIEPPVDYSDDFELCGDVTLQANNTSEDRPQ 180
             R   S+ + R    KS   R +    +    P++  ++ E+     L+  + S   P 
Sbjct: 337 GGRFTRSQEEAR----KSHLARQQQEKEMKTTSPLE-EEEREIKSSQGLKEKSKSPSPP- 390

Query: 181 ELRRSLELSVNLQRKQKDCSSDEYDSIEEDILSEPEPEDPALVGHPRHDRPPSSGDWTQK 240
                        R  +D       ++ E   SE E   P L        P         
Sbjct: 391 -------------RLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPP-------HP 430

Query: 241 DVHGEQETEGRSSPGPDTLVVLEFNPASKSHKRERNLSAKRKDNAEVFVPTKPEPNLTPQ 300
            +H E+E E    P P  L+ L   P + +  RE  +S           P     +   +
Sbjct: 431 QLHSEEEIEPMEGPAPPVLIQLS-PPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAE 489

Query: 301 APAVFPDQERMCSRPGSRRERPLSATRKTLCEAEYPEEDASAVLQAIQVENAALQRALLS 360
           +PA    +E +            SA +        PE D SA    +++E  AL + +  
Sbjct: 490 SPAEKVPEESVLPLVQKSTLADYSAQKDL-----EPESDRSAQPLPLKIEELALAKGITE 544

Query: 361 RKAEQPASPLQDAEGPPAKPWTSLLEEKEETLELLPITTATTTQEPAGAAGGARAINQAM 420
              +QP+  L+  EG  A    +LL        L     +++++  + ++  +R+ +++ 
Sbjct: 545 ECLKQPS--LEQKEGRRAS--HTLLPSH----RLKQSADSSSSRSSSSSSSSSRSRSRSP 596

Query: 421 DRIGLLGSRQQQKLLKVLQAVESDSAHLGRVVSPTKEQVSDTEDKQRMRA 470
           D     GSR    L    + V     H      P     S +E + R R+
Sbjct: 597 DS---SGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRS 643



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 3/128 (2%)

Query: 290  PTKPEPNLTPQAP-AVFPDQERMCSRPGSRRERPLSATRKTLCEAEYPEEDASAVLQAIQ 348
            P  P P   PQ P A   +QER      + RER +    +T  E E+  +      ++  
Sbjct: 1119 PPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRS 1178

Query: 349  VENAALQRALLSRKAEQPASPLQDAEGPPAKPWTSLLEEKEET--LELLPITTATTTQEP 406
                  ++     K ++     +  E PPAK    L  + +    +  LP+T +   Q+ 
Sbjct: 1179 RSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKE 1238

Query: 407  AGAAGGAR 414
            A  A  A+
Sbjct: 1239 AERAERAK 1246


>gi|18379332 WW domain-containing adapter with a coiled-coil region
           isoform 3 [Homo sapiens]
          Length = 544

 Score = 37.7 bits (86), Expect = 0.091
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 664 ETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPPVKC 723
           +  A +  +S  + SG +  S +C   S S        SA PTS   +P +P    P+  
Sbjct: 193 QATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPI-- 250

Query: 724 PPVHEEPSLIQQL 736
           PP+ ++P+L++QL
Sbjct: 251 PPLLQDPNLLRQL 263


>gi|238624188 diffuse panbronchiolitis critical region 1 protein
           [Homo sapiens]
          Length = 1393

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 40/200 (20%), Positives = 75/200 (37%), Gaps = 19/200 (9%)

Query: 757 PSPTGKDRKQGGRKPKPLWLSPEKPLAWKGRLPSDDVIGEGPGETEARDKGLRH------ 810
           PSP      +     +   LSP +P+  + R  +++      G TE R+           
Sbjct: 299 PSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFP 358

Query: 811 -EPGWGTSRSVNTKERPQRATTKVHSDDSDIFNQPPNRERPA--------SGRRGSRKDA 861
            EP     R+ N    P  A    H + +   N  P+   P         +  + +   A
Sbjct: 359 AEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSA 418

Query: 862 GSSSHGDDQPASREDTWSSRTPSRSRWRSEQEHTLHESWSSLSAFDRSHRGRISNTELPG 921
            S+ HG+  P + E+T    TPS +     +E T +E+ +   A    +R   +N +   
Sbjct: 419 ESTEHGERTPLANENT----TPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTL 474

Query: 922 DILDELLQQKSSRHSDLPPS 941
             ++    ++++ +    PS
Sbjct: 475 SPVEPTENRETTANEKTTPS 494


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 40/173 (23%), Positives = 71/173 (41%), Gaps = 16/173 (9%)

Query: 712 PSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDRKQGGRKP 771
           P AP++S P++     +EPS  + +     +   E         QP P+ + R+    + 
Sbjct: 789 PPAPSSSLPIR-----QEPSSFRAVPPPQPQMFGEELPDAQDGEQPGPSRRKRQPSMSET 843

Query: 772 KPLWLSPEKPLAWKGRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKERPQRATT 831
            PL+   ++ L    +   DD++GEG  ++++  +    +      R   T+ R +    
Sbjct: 844 MPLYTLCKEDLESMDK-EVDDILGEGSDDSDSEKRRPEEQEEEPQPRKPGTR-RERTLGA 901

Query: 832 KVHSDDSDIFNQPP-------NRERPAS--GRRGSRKDAGSSSHGDDQPASRE 875
              S+ S    + P       N E  AS   R  S +D GSSS  D+   + E
Sbjct: 902 PASSERSAAGGRGPRGHKRKLNEEDAASESSRESSNEDEGSSSEADEMAKALE 954


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 58/258 (22%), Positives = 93/258 (36%), Gaps = 40/258 (15%)

Query: 166  DVTLQANNTSEDRPQELRRSLELSVNLQRKQKDCSSDEYDSIEEDILSEPEPEDPALVGH 225
            D+T+   N+S++  +E     E     + +++D   +E D  EE+   E E E+      
Sbjct: 877  DLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEED--EEEYFEEEEEEEEEF--- 931

Query: 226  PRHDRPPSSGDWTQKDVHGEQETEGRSSPGPDTLVVLEFNPASKSHKRERNLSAKRKDNA 285
               +     G+  +++   ++E E       D    LEF  A                  
Sbjct: 932  -EEEFEEEEGELEEEEEEEDEEEEEELEEVED----LEFGTA----------------GG 970

Query: 286  EVFVPTKPEPNLTPQAPAVFPDQERMCSRPGSRRERPLSATRKTLCEAEYP--EEDASAV 343
            EV     P P L P  P   P +     +P    E  L      L E E P  EE+  A 
Sbjct: 971  EVEEGAPPPPTLPPALP---PPESPPKVQPEPEPEPGL------LLEVEEPGTEEERGAD 1021

Query: 344  LQAIQVENAALQRALLSRKAEQPAS---PLQDAEGPPAKPWTSLLEEKEETLELLPITTA 400
                    A   +  + R+ E PA+   P +  E  P+ P T L EE E+  + +     
Sbjct: 1022 TAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPE 1081

Query: 401  TTTQEPAGAAGGARAINQ 418
            T  +E       A A+ +
Sbjct: 1082 TPAEEEMETETEAEALQE 1099


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 37.0 bits (84), Expect = 0.16
 Identities = 41/140 (29%), Positives = 56/140 (40%), Gaps = 16/140 (11%)

Query: 644 HEMAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKR-KNSTNCRKDSLSQL------E 696
           ++   +SG   +G+G  PPA+T       SQG V G    N  N      SQL      +
Sbjct: 759 NQFPSSSGAMSVGMG-QPPAQTGV-----SQGQVPGAALPNPLNMLGPQASQLPCPPVTQ 812

Query: 697 EYLRLSAVPTSMG-DMPSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPGKTPS-- 753
             L  +  P S    MPS   T+PP   PP    P+      +  G+     PG  PS  
Sbjct: 813 SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSAT 872

Query: 754 WLQPSPTGKDRKQGGRKPKP 773
             Q +PT +   Q    P+P
Sbjct: 873 QTQSTPTVQAAAQAQVTPQP 892


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 37.0 bits (84), Expect = 0.16
 Identities = 41/140 (29%), Positives = 56/140 (40%), Gaps = 16/140 (11%)

Query: 644 HEMAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKR-KNSTNCRKDSLSQL------E 696
           ++   +SG   +G+G  PPA+T       SQG V G    N  N      SQL      +
Sbjct: 797 NQFPSSSGAMSVGMG-QPPAQTGV-----SQGQVPGAALPNPLNMLGPQASQLPCPPVTQ 850

Query: 697 EYLRLSAVPTSMG-DMPSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPGKTPS-- 753
             L  +  P S    MPS   T+PP   PP    P+      +  G+     PG  PS  
Sbjct: 851 SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSAT 910

Query: 754 WLQPSPTGKDRKQGGRKPKP 773
             Q +PT +   Q    P+P
Sbjct: 911 QTQSTPTVQAAAQAQVTPQP 930


>gi|54124343 hypothetical protein LOC387680 [Homo sapiens]
          Length = 1341

 Score = 37.0 bits (84), Expect = 0.16
 Identities = 77/384 (20%), Positives = 140/384 (36%), Gaps = 46/384 (11%)

Query: 591 KLYVNRNLIFNGKLDKGDREAPADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGAS 650
           KL++ +  +  G+L   +    +D   +VD + EK E+  +   AH  +++        S
Sbjct: 191 KLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMS 250

Query: 651 GDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGD 710
            ++E   GC    +  AD++   + ++    +N+   R    S  +E L       ++G 
Sbjct: 251 DEEEDDDGC----DLFADSE-KEEEDIEDIEENTRPKRSRPTSFADE-LAARIKGDAVGR 304

Query: 711 MPSAPATSPPVKCPP--VHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDRKQGG 768
           +   P T P  +  P    +E    +   +     +  PP  T     P  +G     GG
Sbjct: 305 VDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGG 364

Query: 769 RKPKPLWLSPEKPLAWKGRLPSDDVIGEGPGETEARDKGLRHEP--------------GW 814
              K L+   ++        P D   G    E  +  K  +  P              G 
Sbjct: 365 ---KGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGA 421

Query: 815 GTSRSVNTKERPQRATTKV--------------HSDDSDIFNQPPNRERPASGRRGSRKD 860
            +  S+   ++P++ T +                 DD D F   P+ +   +G+  S  D
Sbjct: 422 ASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTAD 481

Query: 861 AGSSSHGD----DQPASREDTWSSRTPSRSRWRSEQEHTLHESWS-SLSAFDRSHRGRIS 915
                 GD       AS E T S    +++  R+E++ TL  S +   S+  ++ +G  S
Sbjct: 482 IFGDEEGDLFKEKAVASPEATVSQTDENKA--RAEKKVTLSSSKNLKPSSETKTQKGLFS 539

Query: 916 NTELPGDILDELLQQKSSRHSDLP 939
           + E   D+       K    S LP
Sbjct: 540 DEEDSEDLFSSQSASKLKGASLLP 563


>gi|154090959 hypothetical protein LOC55747 [Homo sapiens]
          Length = 1253

 Score = 37.0 bits (84), Expect = 0.16
 Identities = 77/384 (20%), Positives = 140/384 (36%), Gaps = 46/384 (11%)

Query: 591 KLYVNRNLIFNGKLDKGDREAPADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGAS 650
           KL++ +  +  G+L   +    +D   +VD + EK E+  +   AH  +++        S
Sbjct: 103 KLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMS 162

Query: 651 GDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGD 710
            ++E   GC    +  AD++   + ++    +N+   R    S  +E L       ++G 
Sbjct: 163 DEEEDDDGC----DLFADSE-KEEEDIEDIEENTRPKRSRPTSFADE-LAARIKGDAVGR 216

Query: 711 MPSAPATSPPVKCPP--VHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDRKQGG 768
           +   P T P  +  P    +E    +   +     +  PP  T     P  +G     GG
Sbjct: 217 VDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGG 276

Query: 769 RKPKPLWLSPEKPLAWKGRLPSDDVIGEGPGETEARDKGLRHEP--------------GW 814
              K L+   ++        P D   G    E  +  K  +  P              G 
Sbjct: 277 ---KGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGA 333

Query: 815 GTSRSVNTKERPQRATTKV--------------HSDDSDIFNQPPNRERPASGRRGSRKD 860
            +  S+   ++P++ T +                 DD D F   P+ +   +G+  S  D
Sbjct: 334 ASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTAD 393

Query: 861 AGSSSHGD----DQPASREDTWSSRTPSRSRWRSEQEHTLHESWS-SLSAFDRSHRGRIS 915
                 GD       AS E T S    +++  R+E++ TL  S +   S+  ++ +G  S
Sbjct: 394 IFGDEEGDLFKEKAVASPEATVSQTDENKA--RAEKKVTLSSSKNLKPSSETKTQKGLFS 451

Query: 916 NTELPGDILDELLQQKSSRHSDLP 939
           + E   D+       K    S LP
Sbjct: 452 DEEDSEDLFSSQSASKLKGASLLP 475


>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
          Length = 417

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 69/299 (23%), Positives = 98/299 (32%), Gaps = 54/299 (18%)

Query: 608 DREAPADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGASGDKELGLGCSPPAETLA 667
           DRE  A  +   DQ+  +  + EEA  A    S G          K L L C P   T  
Sbjct: 66  DREEEAAAAPAADQQRAQDRE-EEAAAAPVPTSSGHR----TEKRKRLQLQCQPAGGT-- 118

Query: 668 DAKLSSQGNVSGKRKNSTNCRKDSLSQLEEYLRLSAVPTSMGDMPSAPATSPPVKCPP-- 725
                  G   G R +S +  +      EE    + VPTS G          P + P   
Sbjct: 119 -------GQRRGSR-SSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGG 170

Query: 726 ------VHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDRKQGGRKPKPLWLSPE 779
                     PS  QQ     G +  E          P+PT +  +   RKP+     P 
Sbjct: 171 TGQRRGSGSSPSADQQ-----GAQDREEEAAAA----PAPTSRGHRTEKRKPQQPQCRPA 221

Query: 780 KPLAWKGRLPSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKERPQRATTKVHSDDSD 839
                              G T  R +G R  P     R+ + +E    A          
Sbjct: 222 -------------------GGTGQR-RGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRT 261

Query: 840 IFNQPPNRERPASGRRGSRKDAGSSSHGDDQPAS--REDTWSSRTPSRSRWRSEQEHTL 896
              +P   +R  +G  G R+ +G S   D Q A    E+  ++  P+ S  R+E+   L
Sbjct: 262 EKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRL 320


>gi|82830424 gon-4-like isoform a [Homo sapiens]
          Length = 2240

 Score = 36.6 bits (83), Expect = 0.20
 Identities = 69/302 (22%), Positives = 106/302 (35%), Gaps = 54/302 (17%)

Query: 610  EAPADHSILVDQKNEKSEQLEEAMNAHSEESKGTHEMAGAS---------GDKELGLGCS 660
            E   D  +   ++   S    +  ++ S +SK  HE+ G+S         G KE G G  
Sbjct: 1856 EGGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKD 1915

Query: 661  PPAETLADAKLSSQGN--------------VSGKRKNSTNCRKDSLSQLEEYLRLSAVPT 706
               E   + + S++                VSG    ST      ++ + E L L   P 
Sbjct: 1916 MMEEEAPEERESTEATQSRTVRTTRKGEMPVSGLAVGSTLPSPREVT-VTERLLLDGPPP 1974

Query: 707  SMGDMPSAPATSPPVKCPPVHEEPSLIQQLENLMGRKICEPPGKTPSWLQPSPTGKDRKQ 766
               + P  P T+  V          L     N +G ++   P  +P  LQ    G+    
Sbjct: 1975 HSPETPQFPPTTGAV----------LYTVKRNQVGPEVRSCPKASPR-LQKEREGQKAVS 2023

Query: 767  GGRKPKPLW-LSPEKPLAWKGRLPSDDVIGEGPGETEARDKGLRHEPG-------WGTSR 818
                   +W  S  + L      P+  +    P  ++ RD G RH  G       W  S 
Sbjct: 2024 ESEALMLVWDASETEKLPGTVEPPASFL---SPVSSKTRDAGRRHVSGKPDTQERWLPSS 2080

Query: 819  SVNTKERPQRATTKVHSDDSDIFNQPPNRERPASGRRGSRKDAGSSS---HGDDQPASRE 875
                K R +  T  VH   S I     +   P + R G  KD+G+ +    G+ QP + E
Sbjct: 2081 RARVKTRDR--TCPVHESPSGI---DTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAE 2135

Query: 876  DT 877
             T
Sbjct: 2136 AT 2137


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 76/345 (22%), Positives = 121/345 (35%), Gaps = 52/345 (15%)

Query: 638  EESKGTHEMAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEE 697
            E  K   E  G  G K++        ++L   K+ S   +SG+ K        S+S+   
Sbjct: 2177 ETKKIESESKGIKGGKKV-------YKSLITGKVRSNSEISGQMKQPLQANMPSISRGRT 2229

Query: 698  YLRLSAVPTSMGDMPSAPATSPPVKCP--------------PVHEEPSLIQQLENLMGRK 743
             + +  V  S           PP+K P              P   +PS+  +L + + R+
Sbjct: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSEL-SPVARQ 2288

Query: 744  ICEPPG------------KTPSWLQPSPTGKDRKQGGR---KPKPLWLSPEKPLAWKGRL 788
              +  G             TPS     P  +  +  GR    P    +SP   L+   +L
Sbjct: 2289 TSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS---QL 2345

Query: 789  PSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKER--PQRATTKVHSDD-SDIFNQPP 845
            P          ++    K     PG   S+   TK+    + A++   S+  S   NQ  
Sbjct: 2346 PRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMN 2405

Query: 846  N----RERPASGRRGSRKDAGSSSHGDDQPA-SREDTWSSRTPSRSRWRSEQEHTLHESW 900
            N     ++    R  S K +GS S   ++P   R+ T+    PS +  R  +E    ES 
Sbjct: 2406 NGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL 2465

Query: 901  SSLSAFDRSHRGRISNTELPGDILDELLQQKSSRHS----DLPPS 941
            S  S      R +     L   + D  L   SS  +     LPP+
Sbjct: 2466 SPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPN 2510


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 76/345 (22%), Positives = 121/345 (35%), Gaps = 52/345 (15%)

Query: 638  EESKGTHEMAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEE 697
            E  K   E  G  G K++        ++L   K+ S   +SG+ K        S+S+   
Sbjct: 2177 ETKKIESESKGIKGGKKV-------YKSLITGKVRSNSEISGQMKQPLQANMPSISRGRT 2229

Query: 698  YLRLSAVPTSMGDMPSAPATSPPVKCP--------------PVHEEPSLIQQLENLMGRK 743
             + +  V  S           PP+K P              P   +PS+  +L + + R+
Sbjct: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSEL-SPVARQ 2288

Query: 744  ICEPPG------------KTPSWLQPSPTGKDRKQGGR---KPKPLWLSPEKPLAWKGRL 788
              +  G             TPS     P  +  +  GR    P    +SP   L+   +L
Sbjct: 2289 TSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS---QL 2345

Query: 789  PSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKER--PQRATTKVHSDD-SDIFNQPP 845
            P          ++    K     PG   S+   TK+    + A++   S+  S   NQ  
Sbjct: 2346 PRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMN 2405

Query: 846  N----RERPASGRRGSRKDAGSSSHGDDQPA-SREDTWSSRTPSRSRWRSEQEHTLHESW 900
            N     ++    R  S K +GS S   ++P   R+ T+    PS +  R  +E    ES 
Sbjct: 2406 NGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL 2465

Query: 901  SSLSAFDRSHRGRISNTELPGDILDELLQQKSSRHS----DLPPS 941
            S  S      R +     L   + D  L   SS  +     LPP+
Sbjct: 2466 SPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPN 2510


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 76/345 (22%), Positives = 121/345 (35%), Gaps = 52/345 (15%)

Query: 638  EESKGTHEMAGASGDKELGLGCSPPAETLADAKLSSQGNVSGKRKNSTNCRKDSLSQLEE 697
            E  K   E  G  G K++        ++L   K+ S   +SG+ K        S+S+   
Sbjct: 2177 ETKKIESESKGIKGGKKV-------YKSLITGKVRSNSEISGQMKQPLQANMPSISRGRT 2229

Query: 698  YLRLSAVPTSMGDMPSAPATSPPVKCP--------------PVHEEPSLIQQLENLMGRK 743
             + +  V  S           PP+K P              P   +PS+  +L + + R+
Sbjct: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSEL-SPVARQ 2288

Query: 744  ICEPPG------------KTPSWLQPSPTGKDRKQGGR---KPKPLWLSPEKPLAWKGRL 788
              +  G             TPS     P  +  +  GR    P    +SP   L+   +L
Sbjct: 2289 TSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS---QL 2345

Query: 789  PSDDVIGEGPGETEARDKGLRHEPGWGTSRSVNTKER--PQRATTKVHSDD-SDIFNQPP 845
            P          ++    K     PG   S+   TK+    + A++   S+  S   NQ  
Sbjct: 2346 PRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMN 2405

Query: 846  N----RERPASGRRGSRKDAGSSSHGDDQPA-SREDTWSSRTPSRSRWRSEQEHTLHESW 900
            N     ++    R  S K +GS S   ++P   R+ T+    PS +  R  +E    ES 
Sbjct: 2406 NGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL 2465

Query: 901  SSLSAFDRSHRGRISNTELPGDILDELLQQKSSRHS----DLPPS 941
            S  S      R +     L   + D  L   SS  +     LPP+
Sbjct: 2466 SPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPN 2510


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 42/178 (23%), Positives = 63/178 (35%), Gaps = 29/178 (16%)

Query: 213 SEPEPED-----PALVGHPRHDRPPSSGDWTQKDVHGEQETEGRSSPGPDTLVVLEFNPA 267
           S+P+P+      P  V  PR D  P+ G  +   +     +   S   P +L  L   PA
Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320

Query: 268 SKSHKRERNLSAKRKDNAEVFVPTKPEPNLT---PQAP--AVFPDQERMCSRPGSRRERP 322
           +   +   +L +        F+P+ P   L    PQAP     P  +   S P S    P
Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 380

Query: 323 LSATRKTLCEAEYPEEDASAVLQAIQVENAALQRALLSRKAEQPASPLQDAEGPPAKP 380
           L+                     + Q  NA     L +  +  P+ P+Q    PPA P
Sbjct: 381 LAT-------------------PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 42/183 (22%), Positives = 65/183 (35%), Gaps = 22/183 (12%)

Query: 217 PEDPALVGHPRHDRPPSSG---------DWTQKDVHGEQETEGRSSPGP--------DTL 259
           PE     G  R  RPP+SG         + +   V       G + PGP           
Sbjct: 71  PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130

Query: 260 VVLEFNPASKSHKRERNLSAKRKDNAEVFVPTKPEPNLTPQAPAVFPDQERMCSRPGSRR 319
             +    A+++ KR    +  R+D +    P  P P +  ++ A   +       P +R 
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189

Query: 320 ERPLSATRKTLCEA-EYPEEDASAVLQAIQVENAALQRALLSRKAEQPASPLQD--AEGP 376
             P    RK++  A E+   + S   +        LQR   SR     A+PL      GP
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP-ASRSLSSSATPLSSPARSGP 248

Query: 377 PAK 379
            A+
Sbjct: 249 SAR 251


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 36.2 bits (82), Expect = 0.26
 Identities = 40/200 (20%), Positives = 74/200 (37%), Gaps = 19/200 (9%)

Query: 757 PSPTGKDRKQGGRKPKPLWLSPEKPLAWKGRLPSDDVIGEGPGETEARDKGLRH------ 810
           PSP      +     +   LSP +P   + R  +++      G TE R+           
Sbjct: 361 PSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFP 420

Query: 811 -EPGWGTSRSVNTKERPQRATTKVHSDDSDIFNQPPNRERPA--------SGRRGSRKDA 861
            EP     R+ N    P  A    H + +   N  P+   P         +  + +   A
Sbjct: 421 AEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSA 480

Query: 862 GSSSHGDDQPASREDTWSSRTPSRSRWRSEQEHTLHESWSSLSAFDRSHRGRISNTELPG 921
            S+ HG+  P + E+T    TPS +     +E T +E+ +   A    +R   +N +   
Sbjct: 481 ESTEHGERTPLANENT----TPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTL 536

Query: 922 DILDELLQQKSSRHSDLPPS 941
             ++    ++++ +    PS
Sbjct: 537 SPVEPTENRETTANEKTTPS 556


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,200,122
Number of Sequences: 37866
Number of extensions: 3759845
Number of successful extensions: 10984
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 166
Number of HSP's that attempted gapping in prelim test: 10595
Number of HSP's gapped (non-prelim): 576
length of query: 1618
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1502
effective length of database: 13,855,062
effective search space: 20810303124
effective search space used: 20810303124
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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