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Search of human proteins with 194294508
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]
(687 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens] 1335 0.0
gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens] 1335 0.0
gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens] 1334 0.0
gi|21955174 kinesin family member C2 [Homo sapiens] 289 5e-78
gi|167555110 kinesin family member C1 [Homo sapiens] 265 8e-71
gi|46852174 kinesin family member 3A [Homo sapiens] 249 5e-66
gi|4758646 kinesin family member 3B [Homo sapiens] 239 5e-63
gi|4758648 kinesin family member 5B [Homo sapiens] 222 8e-58
gi|41352705 kinesin family member 3C [Homo sapiens] 221 1e-57
gi|116686122 kinesin family member 4 [Homo sapiens] 215 1e-55
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 215 1e-55
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 215 1e-55
gi|150010604 kinesin family member 4B [Homo sapiens] 213 5e-55
gi|4758650 kinesin family member 5C [Homo sapiens] 213 5e-55
gi|45446749 kinesin family member 5A [Homo sapiens] 213 5e-55
gi|46852172 kinesin family member 13B [Homo sapiens] 212 1e-54
gi|40254834 kinesin family member 1C [Homo sapiens] 206 6e-53
gi|13699824 kinesin family member 11 [Homo sapiens] 203 5e-52
gi|122937289 kinesin family member 18B [Homo sapiens] 203 5e-52
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 202 8e-52
gi|156616271 kinesin family member 19 [Homo sapiens] 201 2e-51
gi|30794488 kinesin family member 27 [Homo sapiens] 201 2e-51
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 200 3e-51
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 200 3e-51
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 199 7e-51
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 196 6e-50
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 196 6e-50
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 196 6e-50
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 196 6e-50
gi|7661878 kinesin family member 14 [Homo sapiens] 194 3e-49
>gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens]
Length = 826
Score = 1335 bits (3456), Expect = 0.0
Identities = 687/687 (100%), Positives = 687/687 (100%)
Query: 1 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 60
MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS
Sbjct: 140 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 199
Query: 61 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 120
ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK
Sbjct: 200 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 259
Query: 121 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 180
TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES
Sbjct: 260 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 319
Query: 181 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT 240
ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT
Sbjct: 320 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT 379
Query: 241 NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL 300
NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL
Sbjct: 380 NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL 439
Query: 301 VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ 360
VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ
Sbjct: 440 VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ 499
Query: 361 ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV 420
ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV
Sbjct: 500 ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV 559
Query: 421 QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV 480
QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV
Sbjct: 560 QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV 619
Query: 481 DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE 540
DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE
Sbjct: 620 DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE 679
Query: 541 RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT 600
RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT
Sbjct: 680 RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT 739
Query: 601 LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP 660
LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP
Sbjct: 740 LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP 799
Query: 661 SARAHSAPSSGTSSRPGSIRRKLQPSA 687
SARAHSAPSSGTSSRPGSIRRKLQPSA
Sbjct: 800 SARAHSAPSSGTSSRPGSIRRKLQPSA 826
>gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]
Length = 687
Score = 1335 bits (3456), Expect = 0.0
Identities = 687/687 (100%), Positives = 687/687 (100%)
Query: 1 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 60
MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS
Sbjct: 1 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 60
Query: 61 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 120
ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK
Sbjct: 61 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 120
Query: 121 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 180
TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES
Sbjct: 121 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 180
Query: 181 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT 240
ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT
Sbjct: 181 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT 240
Query: 241 NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL 300
NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL
Sbjct: 241 NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL 300
Query: 301 VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ 360
VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ
Sbjct: 301 VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ 360
Query: 361 ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV 420
ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV
Sbjct: 361 ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV 420
Query: 421 QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV 480
QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV
Sbjct: 421 QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV 480
Query: 481 DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE 540
DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE
Sbjct: 481 DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE 540
Query: 541 RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT 600
RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT
Sbjct: 541 RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT 600
Query: 601 LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP 660
LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP
Sbjct: 601 LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP 660
Query: 661 SARAHSAPSSGTSSRPGSIRRKLQPSA 687
SARAHSAPSSGTSSRPGSIRRKLQPSA
Sbjct: 661 SARAHSAPSSGTSSRPGSIRRKLQPSA 687
>gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]
Length = 833
Score = 1334 bits (3452), Expect = 0.0
Identities = 686/686 (100%), Positives = 686/686 (100%)
Query: 1 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 60
MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS
Sbjct: 140 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 199
Query: 61 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 120
ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK
Sbjct: 200 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 259
Query: 121 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 180
TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES
Sbjct: 260 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 319
Query: 181 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT 240
ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT
Sbjct: 320 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT 379
Query: 241 NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL 300
NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL
Sbjct: 380 NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL 439
Query: 301 VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ 360
VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ
Sbjct: 440 VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ 499
Query: 361 ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV 420
ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV
Sbjct: 500 ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV 559
Query: 421 QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV 480
QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV
Sbjct: 560 QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV 619
Query: 481 DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE 540
DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE
Sbjct: 620 DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE 679
Query: 541 RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT 600
RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT
Sbjct: 680 RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT 739
Query: 601 LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP 660
LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP
Sbjct: 740 LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP 799
Query: 661 SARAHSAPSSGTSSRPGSIRRKLQPS 686
SARAHSAPSSGTSSRPGSIRRKLQPS
Sbjct: 800 SARAHSAPSSGTSSRPGSIRRKLQPS 825
>gi|21955174 kinesin family member C2 [Homo sapiens]
Length = 838
Score = 289 bits (740), Expect = 5e-78
Identities = 197/561 (35%), Positives = 303/561 (54%), Gaps = 55/561 (9%)
Query: 62 LNLEVQQKT-DRLAEVEL-RLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVI 119
L LE Q+ RL ++ L +L++ + Q+EE L R T + R Q
Sbjct: 186 LQLEEDQRAWQRLEQLILGQLEELKQQLEQQEEELGRLRLGVGATDSEKRVQH------- 238
Query: 120 KTVEVESSKTKQALSESQARNQHLQEQVAM-----QRQVLKEMEQQLQSSHQLTARLRAQ 174
+ +E+ KQ+LS + H + + + L E++ +LQ + T LRAQ
Sbjct: 239 --LTLENEALKQSLSLMRDLLLHWGPGPPIRAPQEEAEALLELQGRLQEAQDTTEALRAQ 296
Query: 175 IAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQP 234
+ + E +L+ G + + Q E++ R E++ +H LAG+R + +L+
Sbjct: 297 LGVQEVQLQGLQGALQQLQQETEQNCRR-----------ELQQMHGQLAGLRARMASLRQ 345
Query: 235 ALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRK 294
D GL V F Q +L + ++ A+ ++S ++
Sbjct: 346 GC----GDLRGL---VSTFTQSCQGSLSEARGQVSWALGALSSGGPGTQLPEGQQGP-PA 397
Query: 295 KCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELD 354
C L LKGNIRV+ R+RP T +++ V+ + + ++G+ F LD
Sbjct: 398 GCPGRLPELKGNIRVLCRLRPGT--------SSSLVSVEPGPGGTVTTCYRGRHRRFRLD 449
Query: 355 KVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQ 414
VF P ASQ++VF+E++ V SC+ G++VCIF YGQTG GKTY+MEG E+PGI RALQ
Sbjct: 450 WVFPPDASQEEVFRELEPAVLSCLRGYSVCIFTYGQTGTGKTYSMEGPPEDPGIVPRALQ 509
Query: 415 LLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTE 474
LF E+ + ++ +T+S EIYNE +RDLL P E+L +R P+G G + V GLT
Sbjct: 510 SLFREM---GAGRQHRVTLSMVEIYNEAVRDLLAPGPPERLAVRQGPEGQGGIQVAGLTH 566
Query: 475 FQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLV 534
+ V +++ ++++ + G +NR T T +N+ SSRSHAL+ +T+R T G L+LV
Sbjct: 567 WDVPNLETLHQMLKLGRSNRATAATAMNQRSSRSHALVTLTLRAASPPRAPGTAGTLHLV 626
Query: 535 DLAGSERVGKSGAEG---------SRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSK 585
DLAGSER K+GA G RLREAQ IN+SL ALG V+AALR+ + HVPFR+S+
Sbjct: 627 DLAGSERARKAGAAGPPRGDPDGARRLREAQTINRSLLALGGVMAALRAHRPHVPFRDSQ 686
Query: 586 LTYLLQDSLSGDSKTLMVVQV 606
LT LLQ +L + ++++QV
Sbjct: 687 LTRLLQPALGPGTTAVLLLQV 707
>gi|167555110 kinesin family member C1 [Homo sapiens]
Length = 673
Score = 265 bits (678), Expect = 8e-71
Identities = 189/543 (34%), Positives = 271/543 (49%), Gaps = 54/543 (9%)
Query: 122 VEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESE 181
+ E + ++ NQ LQ+Q+ +Q +K + + + A+++AQ + E
Sbjct: 146 LNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQE 205
Query: 182 LE--RAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTL 239
L+ RA LEE S +E + +++ Q E + + L L T + AL +
Sbjct: 206 LKNLRACVLELEERLSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSS 265
Query: 240 TNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNE 299
+ L+++ LL E +E L E R++ HN+
Sbjct: 266 QAEVASLRQETVAQAALLTE-------------------REERLHGLEME---RRRLHNQ 303
Query: 300 LVRLKGNIRVIARVRPVTKEDGEGP--------------EATNAVTFDADDDSIIHLLHK 345
L LKGNIRV RVRPV + P + ++ D+ L
Sbjct: 304 LQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGA 363
Query: 346 GKPVS---FELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG- 401
P + F D+VF P + Q +VF+E+ LV S +DG+ VCIFAYGQTG+GKT+TMEG
Sbjct: 364 PAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGG 423
Query: 402 ---TAENPGINQRALQLLFSEVQEKASD-WEYTITVSAAEIYNEVLRDLLGKEPQE---- 453
+ G+ RAL+ LFS QE + W Y+ S EIYNE +RDLL ++
Sbjct: 424 PGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGG 483
Query: 454 KLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLI 513
+ EIR GS +L V V +++ + NR T NE SSRSH++
Sbjct: 484 ECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQ 543
Query: 514 VTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEG----SRLREAQHINKSLSALGDVI 569
+ + G S GL+ L+LVDLAGSER+ A G RLRE Q IN SLS LG VI
Sbjct: 544 LQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVI 603
Query: 570 AALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 629
AL +++ HVP+RNSKLTYLLQ+SL G +K LM V +SP+E+N SE+L SL+FA +V
Sbjct: 604 MALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQC 663
Query: 630 ELG 632
+G
Sbjct: 664 VIG 666
Score = 34.3 bits (77), Expect = 0.39
Identities = 43/174 (24%), Positives = 71/174 (40%), Gaps = 22/174 (12%)
Query: 3 ENERLRQEMRRCEAELQEL---RTKPAGPCPGCEHSQESAQLRDK-LSQLQLEMAESKGM 58
EN++L+ ++R + +++ L RT G + E Q K L LE+ E
Sbjct: 163 ENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLST 222
Query: 59 LSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYV 118
L E+Q+K L E L L EK + + L S +ASLR
Sbjct: 223 QEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQ-------- 274
Query: 119 IKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLR 172
E+ L+E + R L+ M+R+ L Q+L+ + ++ R+R
Sbjct: 275 ------ETVAQAALLTEREERLHGLE----MERRRLHNQLQELKGNIRVFCRVR 318
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 249 bits (637), Expect = 5e-66
Identities = 141/337 (41%), Positives = 211/337 (62%), Gaps = 16/337 (4%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSI-IHLLHKGK--PVSFELDKVFSPQAS 362
N++V+ R RP+ + + + AV+ D +I +H P +F D VF P++
Sbjct: 14 NVKVVVRCRPLNERE-KSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESK 72
Query: 363 QQDVFQ-EVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFS 418
Q DV+ + ++ S ++G+N IFAYGQTG GKT+TMEG P GI + +F
Sbjct: 73 QLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFG 132
Query: 419 EVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQ 478
+ + D + + VS EIYNE +RDLLGK+ ++LE++ PD +Y+ L+ + V
Sbjct: 133 HIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVG--VYIKDLSAYVVN 190
Query: 479 SVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV----RGVDCSTGLRTTGKLNLV 534
+ DD++++ GH NR+ TN+NEHSSRSHA+ +T+ +G+D + +R GKL+LV
Sbjct: 191 NADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRM-GKLHLV 249
Query: 535 DLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQDS 593
DLAGSER K+GA G RL+EA IN SLS LG+VI+AL + HVP+RNSKLT LLQDS
Sbjct: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDS 309
Query: 594 LSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVE 630
L G+SKT+M + P + N ET+ +L++A R ++++
Sbjct: 310 LGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIK 346
Score = 43.1 bits (100), Expect = 8e-04
Identities = 46/202 (22%), Positives = 89/202 (44%), Gaps = 41/202 (20%)
Query: 9 QEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMA-----------ESKG 57
+E + AEL++ R K + QE L +KLS L+ ++ E +
Sbjct: 442 EERNKARAELEK-REKDL-----LKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEK 495
Query: 58 MLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKY 117
+L E N+E++++ R ++ L++ +E+ERL D E SL+ ++
Sbjct: 496 LLEESNMELEERRKRAEQLRRELEE------KEQERL-----DIEEKYTSLQEEAQGKTK 544
Query: 118 VIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAM 177
+K V K +++ Q +Q +E+E L++ QL+ LR Q+ +
Sbjct: 545 KLKKVWTMLMAAKSEMADLQQEHQ-------------REIEGLLENIRQLSRELRLQMLI 591
Query: 178 YESELERAHGQMLEEMQSLEED 199
++ + R + +M+E ED
Sbjct: 592 IDNFIPRDYQEMIENYVHWNED 613
Score = 35.8 bits (81), Expect = 0.14
Identities = 50/238 (21%), Positives = 94/238 (39%), Gaps = 30/238 (12%)
Query: 81 KDCLAEKAQEE-ERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQAR 139
KD L + Q+E E L ++L + E S + S V + K K+ + +
Sbjct: 356 KDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVS 415
Query: 140 NQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERA---HGQMLE----- 191
+ E A + K +E +L + + RA++ E +L +A H +LE
Sbjct: 416 PDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSAL 475
Query: 192 ----------------EMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPA 235
E + L E+ N +EE RA+ + + E L ++
Sbjct: 476 EKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK----EQERLDIEEK 531
Query: 236 LRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLR 293
+L + G ++++ +L A +S A++ Q + E +R+ REL+L+
Sbjct: 532 YTSLQEEAQGKTKKLKKVWTMLM-AAKSEMADLQQEHQREIEGLLENIRQLSRELRLQ 588
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 239 bits (611), Expect = 5e-63
Identities = 143/341 (41%), Positives = 207/341 (60%), Gaps = 18/341 (5%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGK----PVSFELDKVFSPQA 361
++RV+ R RP+ ++ + V D + KG P +F D V+ A
Sbjct: 9 SVRVVVRCRPMNGKE-KAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNA 67
Query: 362 SQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLF 417
Q +++ E + LV S + GFN IFAYGQTG GKTYTMEG +P G+ + +F
Sbjct: 68 KQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHIF 127
Query: 418 SEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 477
+ + ++ + +Y + S EIY E +RDLL K+ ++LE++ PD +YV L+ F
Sbjct: 128 THIS-RSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTG--VYVKDLSSFVT 184
Query: 478 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVR----GVDCSTGLRTTGKLNL 533
+SV +I V G+ NR+ TN+NEHSSRSHA+ ++T+ G+D +R GKLNL
Sbjct: 185 KSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRV-GKLNL 243
Query: 534 VDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQD 592
VDLAGSER K+GA+G RL+EA IN SLSALG+VI+AL + H+P+R+SKLT LLQD
Sbjct: 244 VDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQD 303
Query: 593 SLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGP 633
SL G++KT+MV V P N ETL +L++A R ++++ P
Sbjct: 304 SLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKP 344
Score = 31.2 bits (69), Expect = 3.3
Identities = 32/136 (23%), Positives = 62/136 (45%), Gaps = 11/136 (8%)
Query: 33 EHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEE 92
E ++ LR + ++ A+ K M S+L + + D E + L +K QE
Sbjct: 445 EKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQ----KILEQKRQEIA 500
Query: 93 RLSRRLRDSHETIASLRAQSPPVKYVIKT----VEVESSKTKQALSESQARNQH---LQE 145
RR R+ + + S ++ +K + V++++ K K+ S+ QA LQE
Sbjct: 501 EQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQE 560
Query: 146 QVAMQRQVLKEMEQQL 161
+ +RQ L++ + +L
Sbjct: 561 EHIKERQELEQTQNEL 576
Score = 29.6 bits (65), Expect = 9.7
Identities = 47/254 (18%), Positives = 104/254 (40%), Gaps = 61/254 (24%)
Query: 8 RQEMRRCEAELQ----------ELRTKPAGPCPGCEHSQESAQLRD----------KLSQ 47
++E+ R +A+L+ E R + G G E +E + + + Q
Sbjct: 359 QEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQ 418
Query: 48 LQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEK-----------AQEEERL-- 94
+LE+ E + ++ + +L ++K L E E +++D EK A E + L
Sbjct: 419 EKLEI-EKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVG 477
Query: 95 -----------SRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHL 143
+ L + IA + + ++ +++ + E+ + K+ S L
Sbjct: 478 GKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSS-------L 530
Query: 144 QEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLE------ 197
Q++V ++ + LK++ +LQ+ L+ + ELE+ ++ E++
Sbjct: 531 QQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENF 590
Query: 198 ---EDKNRAIEEAF 208
E+K++ + AF
Sbjct: 591 IPLEEKSKIMNRAF 604
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 222 bits (566), Expect = 8e-58
Identities = 134/329 (40%), Positives = 201/329 (61%), Gaps = 14/329 (4%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 365
NI+V+ R RP+ + + + A F +D +I KP +F D+VF SQ+
Sbjct: 8 NIKVMCRFRPLNESEVNRGDKYIA-KFQGEDTVVI----ASKPYAF--DRVFQSSTSQEQ 60
Query: 366 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 421
V+ + + +V ++G+N IFAYGQT +GKT+TMEG +P GI R +Q +F+ +
Sbjct: 61 VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY 120
Query: 422 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 481
+ E+ I VS EIY + +RDLL K + + D + YV G TE V S D
Sbjct: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLSVHEDKNRVPYVKGCTERFVCSPD 177
Query: 482 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 541
++ + G +NR TN+NEHSSRSH++ ++ V+ + T + +GKL LVDLAGSE+
Sbjct: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEK 237
Query: 542 VGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTL 601
V K+GAEG+ L EA++INKSLSALG+VI+AL +VP+R+SK+T +LQDSL G+ +T
Sbjct: 238 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTT 297
Query: 602 MVVQVSPVEKNTSETLYSLKFAERVRSVE 630
+V+ SP N SET +L F +R ++++
Sbjct: 298 IVICCSPSSYNESETKSTLLFGQRAKTIK 326
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 221 bits (564), Expect = 1e-57
Identities = 143/365 (39%), Positives = 209/365 (57%), Gaps = 44/365 (12%)
Query: 307 IRVIARVRPVT-KEDGEGPEATNAVTFDADDDSIIHLLHKGKP----VSFELDKVFSPQA 361
++V+AR RP++ KE+ G E +T D + + P +F D V+ +
Sbjct: 11 LKVVARCRPLSRKEEAAGHE--QILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASS 68
Query: 362 SQQDVFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLF 417
Q D++ E V+ L+ S + GFN +FAYGQTG GKTYTM+GT P G+ A + +F
Sbjct: 69 KQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIF 128
Query: 418 SEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 477
+ + ++ + +Y + S EIY E +RDLL KEP ++LE++ P+ +Y+ L+ F
Sbjct: 129 THIS-RSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETG--VYIKDLSSFVT 185
Query: 478 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV----RGVDCSTGLRTTGKLNL 533
++V +I V G+ R T++NE SSRSHA+ I+TV RG D +R GKLNL
Sbjct: 186 KNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRV-GKLNL 244
Query: 534 VDLAGSERVGKSG------------------------AEGSRLREAQHINKSLSALGDVI 569
VDLAGSER K+G A G R +EA IN SLSALG+VI
Sbjct: 245 VDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVI 304
Query: 570 AALR-SRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 628
AAL +R H+P+R+SKLT LLQDSL G++KT+MV + P + E+L +L+FA R ++
Sbjct: 305 AALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKN 364
Query: 629 VELGP 633
++ P
Sbjct: 365 IKNKP 369
Score = 38.9 bits (89), Expect = 0.016
Identities = 54/257 (21%), Positives = 99/257 (38%), Gaps = 29/257 (11%)
Query: 79 RLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALS---- 134
R K+ + E+ LR+ E IA L+AQ + K +SS+ K+A+S
Sbjct: 361 RAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG 420
Query: 135 --------------ESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 180
E N H Q ++ + K ME LQ + +A I S
Sbjct: 421 YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS 480
Query: 181 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLL----TLQPAL 236
+ ++LEE + + ED R ++A + KA+ L N++ Q L
Sbjct: 481 LVSEEKQKLLEEKEKMLEDLRRE-QQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKML 539
Query: 237 RTLTNDYNGLKRQVRGFP---LLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLR 293
+ KR+ R +L E ++ +EV ++L + Y + ++
Sbjct: 540 ELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVK 599
Query: 294 KKC---HNELVRLKGNI 307
+ H+E +R++ ++
Sbjct: 600 AEIQDQHDEYIRVRQDL 616
Score = 36.6 bits (83), Expect = 0.079
Identities = 34/176 (19%), Positives = 77/176 (43%), Gaps = 33/176 (18%)
Query: 61 ELNLE--VQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYV 118
E N+E +Q++ +RL E + ++D + ++E+++L L + + + LR + + +
Sbjct: 454 EKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKL---LEEKEKMLEDLRREQQATELL 510
Query: 119 IKTVEVESSKT-------KQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARL 171
+ SK +E Q + ++++A Q++ +EM+Q++ + T L
Sbjct: 511 AAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMEL 570
Query: 172 R---------------------AQIAMYESELERAHGQMLEEMQSLEEDKNRAIEE 206
R A++ ++E++ H + + Q LEE +N E
Sbjct: 571 RGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRE 626
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 215 bits (548), Expect = 1e-55
Identities = 144/341 (42%), Positives = 201/341 (58%), Gaps = 24/341 (7%)
Query: 307 IRVIARVRP-VTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 365
+RV R RP V KE EG + ++F + ++ G SF D VF P Q++
Sbjct: 10 VRVALRCRPLVPKEISEGCQM--CLSFVPGEPQVV----VGTDKSFTYDFVFDPSTEQEE 63
Query: 366 VFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEG--TAENP-----GINQRALQLLF 417
VF A L+ G+N + AYGQTG+GKTY+M G TAE G+ R +QLLF
Sbjct: 64 VFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLF 123
Query: 418 SEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 477
E+ +K SD+E+T+ VS EIYNE + DLL +EK +I + D + + GLTE V
Sbjct: 124 KEIDKK-SDFEFTLKVSYLEIYNEEILDLLCPS-REKAQINIREDPKEGIKIVGLTEKTV 181
Query: 478 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV---RGVDCSTGLRTTGKLNLV 534
D E G+ +RT T +N SSRSHA+ +++ + D ++ R+ KL+LV
Sbjct: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRS--KLHLV 239
Query: 535 DLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRS--RQGHVPFRNSKLTYLLQD 592
DLAGSER K+ AEG RL+E +IN+ L LG+VI+AL + G VP+R+SKLT LLQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQD 299
Query: 593 SLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGP 633
SL G+S TLM+ VSP + N ETL +L++A+R R ++ P
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKP 340
Score = 43.1 bits (100), Expect = 8e-04
Identities = 39/190 (20%), Positives = 85/190 (44%), Gaps = 18/190 (9%)
Query: 40 QLRDKLSQLQLEMAESKGMLSELNLEVQ-------------QKTDRLAEVELRLKDCLAE 86
Q +D + +L+LE+ + EL LE+Q ++ RL E+E ++ D L +
Sbjct: 556 QYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIAD-LKK 614
Query: 87 KAQEEERLSRRLRDSHETIASLRAQSPPVK----YVIKTVEVESSKTKQALSESQARNQH 142
K E+ +L + + T++ L + +K +++ ++ ++ K +Q +
Sbjct: 615 KLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQ 674
Query: 143 LQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNR 202
L+E+ ++ L ++E+ Q + R + A L+ A + E +E ++R
Sbjct: 675 LKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSR 734
Query: 203 AIEEAFARAQ 212
+E AR +
Sbjct: 735 GMEGTAARVK 744
Score = 39.7 bits (91), Expect = 0.009
Identities = 51/239 (21%), Positives = 107/239 (44%), Gaps = 47/239 (19%)
Query: 35 SQESAQLRDK----------LSQLQLEMAESKGMLSE-----------LNLEVQQKTDRL 73
+Q+ AQL++K L + + E +G +SE L E++ ++ ++
Sbjct: 775 AQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQI 834
Query: 74 AEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTV---EVESSKTK 130
A+++ +L D A+ E+R +R E IA++ +KY+I + +++ SK +
Sbjct: 835 ADLQQKLLD-----AESEDRPKQRW----ENIATILEAKCALKYLIGELVSSKIQVSKLE 885
Query: 131 QALSESQA------------RNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMY 178
+L +S+ RN + + +Q ++++ MEQQ Q Q M
Sbjct: 886 SSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVR-MEQQHQEKVLYLLSQLQQSQMA 944
Query: 179 ESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALR 237
E +LE + + +++ S + ++ +E+ + + + EN ++ L LQ A R
Sbjct: 945 EKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEI-IKQKLTLLQVASR 1002
Score = 37.7 bits (86), Expect = 0.036
Identities = 64/316 (20%), Positives = 136/316 (43%), Gaps = 41/316 (12%)
Query: 1 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 60
M++N+R+ Q MR+ + + ++ R + +E QL+++ + Q E+ + +
Sbjct: 642 MMKNQRV-QLMRQMKEDAEKFRQWKQ------KKDKEVIQLKERDRKRQYELLKLERNFQ 694
Query: 61 ELNLEVQQKTDRLAEVELRLKDCL------AEKAQEEE---------RLSRRLRDSHETI 105
+ + +++KT+ A RLKD L A+K +E + R+ L + E +
Sbjct: 695 KQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVM 754
Query: 106 ASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSH 165
S + +++ ++ + Q L E + ++ ++ + L E+ Q+ S
Sbjct: 755 VSTEEAKRHLNDLLEDRKILAQDVAQ-LKEKKESGENPPPKLRRRTFSLTEVRGQVSESE 813
Query: 166 QLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGV 225
+ QI E+E+E Q+ + Q L + A ++ K EN+A
Sbjct: 814 D---SITKQIESLETEMEFRSAQIADLQQKLLD----------AESEDRPKQRWENIA-- 858
Query: 226 RTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRK 285
+L + AL+ L + K QV L+++ S A++ + + E ++ E+ +
Sbjct: 859 --TILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSC-ADMQKMLFEERNHFAEIETE 915
Query: 286 YRRELQLRKKCHNELV 301
+ EL ++ H E V
Sbjct: 916 LQAELVRMEQQHQEKV 931
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 215 bits (548), Expect = 1e-55
Identities = 154/398 (38%), Positives = 221/398 (55%), Gaps = 28/398 (7%)
Query: 307 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGK----PVSFELDKVFSPQAS 362
++V+ R RP+ + + E VT D + + G P F D +
Sbjct: 6 VKVVVRCRPMNQRERE-LRCQPVVTVDCARAQCC-IQNPGAADEPPKQFTFDGAYHVDHV 63
Query: 363 QQDVFQEVQ-ALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFS 418
+ ++ E+ LV +G+N IFAYGQTG+GK++TM+G + P GI RA + +F
Sbjct: 64 TEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFE 123
Query: 419 EVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQ 478
VQ A + ++ + S EIYNE +RDLLG + ++KLE++ P+ +YV GL+ V
Sbjct: 124 SVQ-CAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKG--VYVKGLSMHTVH 180
Query: 479 SVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV-------RGVDCSTGLRTTGKL 531
SV + E G NR+ +T +N+ SSRSH++ +++ RG D LR GKL
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKD---HLRA-GKL 236
Query: 532 NLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLL 590
NLVDLAGSER K+GA G RL+EA IN SLSALG+VI+AL R HVP+R+SKLT LL
Sbjct: 237 NLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLL 296
Query: 591 QDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSW--SSQEH 648
QDSL G++KTLMV +SP + N ETL +L++A R +++ P + + QE
Sbjct: 297 QDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEE 356
Query: 649 LEWEPACQTPQPSARAHSA-PSSGTSSRPGSIRRKLQP 685
++ A T Q S + SA S P + KL P
Sbjct: 357 IKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLP 394
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 215 bits (548), Expect = 1e-55
Identities = 154/398 (38%), Positives = 221/398 (55%), Gaps = 28/398 (7%)
Query: 307 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGK----PVSFELDKVFSPQAS 362
++V+ R RP+ + + E VT D + + G P F D +
Sbjct: 6 VKVVVRCRPMNQRERE-LRCQPVVTVDCARAQCC-IQNPGAADEPPKQFTFDGAYHVDHV 63
Query: 363 QQDVFQEVQ-ALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFS 418
+ ++ E+ LV +G+N IFAYGQTG+GK++TM+G + P GI RA + +F
Sbjct: 64 TEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFE 123
Query: 419 EVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQ 478
VQ A + ++ + S EIYNE +RDLLG + ++KLE++ P+ +YV GL+ V
Sbjct: 124 SVQ-CAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKG--VYVKGLSMHTVH 180
Query: 479 SVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV-------RGVDCSTGLRTTGKL 531
SV + E G NR+ +T +N+ SSRSH++ +++ RG D LR GKL
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKD---HLRA-GKL 236
Query: 532 NLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLL 590
NLVDLAGSER K+GA G RL+EA IN SLSALG+VI+AL R HVP+R+SKLT LL
Sbjct: 237 NLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLL 296
Query: 591 QDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSW--SSQEH 648
QDSL G++KTLMV +SP + N ETL +L++A R +++ P + + QE
Sbjct: 297 QDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEE 356
Query: 649 LEWEPACQTPQPSARAHSA-PSSGTSSRPGSIRRKLQP 685
++ A T Q S + SA S P + KL P
Sbjct: 357 IKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLP 394
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 213 bits (542), Expect = 5e-55
Identities = 144/341 (42%), Positives = 200/341 (58%), Gaps = 24/341 (7%)
Query: 307 IRVIARVRP-VTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 365
+RV R RP V KE EG + ++F + ++ G SF D VF P Q++
Sbjct: 10 VRVALRCRPLVPKEISEGCQM--CLSFVPGETQVV----VGTDKSFTYDFVFDPCTEQEE 63
Query: 366 VFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEG--TAENP-----GINQRALQLLF 417
VF + A L+ G+N + AYGQTG+GKTY+M G TAE GI R +QLLF
Sbjct: 64 VFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLF 123
Query: 418 SEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 477
E+ +K SD+E+T+ VS EIYNE + DLL +EK +I + D + + GLTE V
Sbjct: 124 KEIDKK-SDFEFTLKVSYLEIYNEEILDLLCPS-REKAQINIREDPKEGIKIVGLTEKTV 181
Query: 478 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV---RGVDCSTGLRTTGKLNLV 534
D E G+ +RT T +N SSRSHA+ +++ + D + R+ KL+LV
Sbjct: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRS--KLHLV 239
Query: 535 DLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRS--RQGHVPFRNSKLTYLLQD 592
DLAGSER K+ AEG RL+E +IN+ L LG+VI+AL + VP+R+SKLT LLQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQD 299
Query: 593 SLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGP 633
SL G+S TLM+ VSP + N ETL +L++A+R R ++ P
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKP 340
Score = 37.7 bits (86), Expect = 0.036
Identities = 65/316 (20%), Positives = 141/316 (44%), Gaps = 41/316 (12%)
Query: 1 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 60
M++N+R+ Q MR+ + + ++ R + +E QL+++ + Q E+ + +
Sbjct: 642 MMKNQRV-QLMRQMKEDAEKFRQWKQ------KKDKEVIQLKERDRKRQYELLKLERNFQ 694
Query: 61 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 120
+ + +++KT+ A RLKD L ++ + ++ E IA+ R ++ ++
Sbjct: 695 KQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAA-RVRN----WLGN 749
Query: 121 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 180
+EV + ++ +HL + + R++L + QL+ + ++
Sbjct: 750 EIEV--------MVSTEEAKRHLND-LLEDRKILAQDVVQLKEKKESRENPPPKLRKCTF 800
Query: 181 ELERAHGQMLE-------EMQSLE-EDKNRAIEEA-------FARAQVEMKAVHENLAGV 225
L HGQ+LE +++SLE E + R+ + A A ++ K EN+A
Sbjct: 801 SLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIA-- 858
Query: 226 RTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRK 285
+L + AL+ L + K V L+++ S A++ + + E ++ E+ +
Sbjct: 859 --TILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASC-ADMQKMLFEEQNHFSEIETE 915
Query: 286 YRRELQLRKKCHNELV 301
+ EL ++ H E V
Sbjct: 916 LQAELVRMEQQHQEKV 931
Score = 37.0 bits (84), Expect = 0.061
Identities = 44/218 (20%), Positives = 100/218 (45%), Gaps = 30/218 (13%)
Query: 45 LSQLQLEMAESKGMLSE----LNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRD 100
LS++ ++ ES+ +++ L E++ ++ ++A+++ +L D +E R +
Sbjct: 802 LSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESED---------RPKQ 852
Query: 101 SHETIASLRAQSPPVKYVIKTV---EVESSKTKQALSESQARNQHLQEQVAMQRQVLKE- 156
E IA++ +KY+I + ++ +K + +L +S+A +Q+ + ++ E
Sbjct: 853 CWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEI 912
Query: 157 ----------MEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEE 206
MEQQ Q + M E +LE++ + +++ S + ++ +E+
Sbjct: 913 ETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEK 972
Query: 207 AFARAQVEMKAVHENLAGVRTNLLTLQPALRT--LTND 242
+ + + EN ++ L+ LQ A R L ND
Sbjct: 973 MREVCEQNQQLLQENEI-IKQKLILLQVASRQKHLPND 1009
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 213 bits (542), Expect = 5e-55
Identities = 129/330 (39%), Positives = 199/330 (60%), Gaps = 14/330 (4%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 365
+I+V+ R RP+ + E + D++++ + +GKP F D+V P +Q+
Sbjct: 8 SIKVMCRFRPLN--EAEILRGDKFIPKFKGDETVV--IGQGKPYVF--DRVLPPNTTQEQ 61
Query: 366 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 421
V+ + +V ++G+N IFAYGQT +GKT+TMEG +P GI R +F +
Sbjct: 62 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 121
Query: 422 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 481
+ E+ I VS EIY + +RDLL K + + D + YV G TE V S +
Sbjct: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLAVHEDKNRVPYVKGCTERFVSSPE 178
Query: 482 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 541
++ V + G NR TN+NEHSSRSH++ ++ ++ + T + +GKL LVDLAGSE+
Sbjct: 179 EVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEK 238
Query: 542 VGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQDSLSGDSKT 600
V K+GAEG+ L EA++INKSLSALG+VI+AL + HVP+R+SK+T +LQDSL G+ +T
Sbjct: 239 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRT 298
Query: 601 LMVVQVSPVEKNTSETLYSLKFAERVRSVE 630
+V+ SP N +ET +L F +R ++++
Sbjct: 299 TIVICCSPSVFNEAETKSTLMFGQRAKTIK 328
Score = 50.4 bits (119), Expect = 5e-06
Identities = 76/329 (23%), Positives = 135/329 (41%), Gaps = 42/329 (12%)
Query: 2 VENERLRQEMRRCEAELQELRTKPAGPCPGCEH-SQESAQLRDKLSQLQLEMAESKGMLS 60
+ENE + E++ L+EL E ++ + QL D+L+Q + ++ LS
Sbjct: 475 IENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELS 534
Query: 61 ELNLEVQQKTDRLAEV-ELRLKDC--------------LAEK--AQEEERLSRRLRDSH- 102
+L + R E+ L LKD LA+ EEE RL S
Sbjct: 535 QLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKM 594
Query: 103 -ETIASLRAQSPPVKYV-------IKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVL 154
+ SL +S ++ + E E + + +S+ +A+ + L + + Q
Sbjct: 595 KSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKR 654
Query: 155 KEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDK----------NRAI 204
+++E+ S + A+LRAQ M+E + + L +Q EE K A
Sbjct: 655 RQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAH 714
Query: 205 EEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLK-----RQVRGFPLLLQE 259
++ +R + E++ + + +R LQ L++DYN LK R+++ LLL
Sbjct: 715 QKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLN 774
Query: 260 ALRSVKAEIGQAIEEVNSNNQELLRKYRR 288
R E + +EE S + L R+
Sbjct: 775 DKREQAREDLKGLEETVSRELQTLHNLRK 803
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 213 bits (542), Expect = 5e-55
Identities = 131/330 (39%), Positives = 199/330 (60%), Gaps = 15/330 (4%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 365
+I+V+ R RP+ + + + + F DD +I GKP F D+VF P +Q+
Sbjct: 9 SIKVLCRFRPLNQAEILRGDKFIPI-FQGDDSVVIG----GKPYVF--DRVFPPNTTQEQ 61
Query: 366 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 421
V+ +V + G+N IFAYGQT +GKT+TMEG +P GI R + +F+ +
Sbjct: 62 VYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIY 121
Query: 422 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 481
+ E+ I VS EIY + +RDLL K + + D + +V G TE V S +
Sbjct: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDVT---KTNLSVHEDKNRVPFVKGCTERFVSSPE 178
Query: 482 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 541
+I V + G +NR TN+NEHSSRSH++ ++ ++ + T + +GKL LVDLAGSE+
Sbjct: 179 EILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEK 238
Query: 542 VGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQDSLSGDSKT 600
V K+GAEG+ L EA++INKSLSALG+VI+AL + +VP+R+SK+T +LQDSL G+ +T
Sbjct: 239 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRT 298
Query: 601 LMVVQVSPVEKNTSETLYSLKFAERVRSVE 630
M + SP N +ET +L F +R ++++
Sbjct: 299 TMFICCSPSSYNDAETKSTLMFGQRAKTIK 328
Score = 45.8 bits (107), Expect = 1e-04
Identities = 56/290 (19%), Positives = 124/290 (42%), Gaps = 42/290 (14%)
Query: 47 QLQLEMAESKGMLSELNLEVQQKTDRLAEVEL-RLKDCLAEKAQEEERLSRRLRDSHETI 105
+L E + K + + Q++T E EL R ++ E E ERL+ +
Sbjct: 336 ELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRN--GENVPETERLA----GEEAAL 389
Query: 106 ASLRAQSPPVK----YVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 161
+ + PV V++ E K ++ + + +++ Q Q++++++QQ+
Sbjct: 390 GAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQM 449
Query: 162 QSSHQLTARLRA-------QIAMYESELERAHGQMLEEMQSLEE------DKNRAIEEAF 208
+L R +++ +SE + A ++ E +Q+LEE K++ +EE
Sbjct: 450 LDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKS 509
Query: 209 ARAQVEMKAVHENLA---GVRTNLLTLQPA----LRTLTNDYNGLKRQVRGFPLLLQEAL 261
+ Q+ + + + +A + + L LQ + + NGL + + F +++
Sbjct: 510 QQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGE 569
Query: 262 RSVKAEIGQAIEE-----------VNSNNQELLRKYRRELQLRKKCHNEL 300
+ EI AIEE + S + ++++ R+ L+ +CH ++
Sbjct: 570 IKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKM 619
Score = 35.8 bits (81), Expect = 0.14
Identities = 73/325 (22%), Positives = 129/325 (39%), Gaps = 34/325 (10%)
Query: 3 ENERLRQEMRRCEAELQELRTKPAGPCPGCEH-SQESAQLRDKLSQLQLEMAESKGMLSE 61
EN+ + E++ L+EL E SQ++ L D+LSQ M + L
Sbjct: 476 ENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQR 535
Query: 62 LNLEVQQKTDRLAEVELRLKDCLAE----KAQEEERLSRRLRDSHE---TIASLRAQ--S 112
L + R+AEV L L+E E +L + + E T+A L
Sbjct: 536 LQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIK 595
Query: 113 PPVKYVIK--------------TVEV---ESSKTKQALSESQARNQHLQEQVAMQRQVLK 155
VK V+K +EV E S + +S+ +A+ + L E + +
Sbjct: 596 SEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKR 655
Query: 156 EMEQQLQSSHQLTARLRAQ-----IAMYESELERAHGQMLEEMQSLEEDKNR-AIEEAFA 209
+E+ S A+L+AQ +A+ + E + +++ L+ + +R A A
Sbjct: 656 HLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLA 715
Query: 210 RAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIG 269
R + E+ + + ++ LQ L L DY LK + LQE L +
Sbjct: 716 RLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQE-LTFLYERHE 774
Query: 270 QAIEEVNSNNQELLRKYRRELQLRK 294
Q+ +++ + + R+ + LRK
Sbjct: 775 QSKQDLKGLEETVARELQTLHNLRK 799
Score = 33.1 bits (74), Expect = 0.88
Identities = 38/173 (21%), Positives = 76/173 (43%), Gaps = 12/173 (6%)
Query: 40 QLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVEL---RLKDCLAEKAQEEERLSR 96
+L+D +LQLE+ + + +L E +K+ +L E+ R + + EE ++R
Sbjct: 730 ELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVAR 789
Query: 97 RLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQA---RNQHLQEQVAMQRQV 153
L+ H + L Q + V K+ E+E + S+ Q +L++ + +Q+
Sbjct: 790 ELQTLH-NLRKLFVQDVTTR-VKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQL 847
Query: 154 LKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEE 206
+++ +L RLRA ++ G + E + +DK R +E
Sbjct: 848 VRDNADLRCELPKLEKRLRAT----AERVKALEGALKEAKEGAMKDKRRYQQE 896
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 212 bits (539), Expect = 1e-54
Identities = 139/354 (39%), Positives = 201/354 (56%), Gaps = 37/354 (10%)
Query: 307 IRVIARVRPVTKEDGEGPEA------TNAVTFDADDDSIIHLLHKGKPVSFELDKVF--- 357
++V R+RP+ + + + N V + + ++ +G+P F D F
Sbjct: 6 VKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFWSM 65
Query: 358 -----SPQASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQR 411
A Q VF+ + + ++ + DG+N CIFAYGQTG+GK+YTM GTA+ PG+ R
Sbjct: 66 DESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPR 125
Query: 412 ALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR----LCPDGSG 465
LF Q E+ + + + VS EIYNE +RDLL K ++ L++R L P
Sbjct: 126 LCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGP---- 181
Query: 466 QLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVR----GVDC 521
YV GL++ V S DI + G+ +RT TN+NE SSRSHA+ +T+ V
Sbjct: 182 --YVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKS 239
Query: 522 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL------RSR 575
T GKL+LVDLAGSER K+GA G RL+E +INKSL+ LG VI+AL +++
Sbjct: 240 GTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNK 299
Query: 576 QGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 629
VP+R+S LT+LL+DSL G+SKT MV VSP N ETL +L++A+R + +
Sbjct: 300 NKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHI 353
Score = 30.4 bits (67), Expect = 5.7
Identities = 31/147 (21%), Positives = 58/147 (39%), Gaps = 25/147 (17%)
Query: 122 VEVESSKTKQALSESQARNQHLQEQVAMQ--------RQVLKEMEQQLQSSHQLTARLRA 173
++V+ + + SE ++ Q +V M+ + +L +EQQ + + + L
Sbjct: 571 LDVDGDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKR--SALER 628
Query: 174 QIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQ 233
Q MYE ELE+ ++ E Q+ + A+ ++ A
Sbjct: 629 QRLMYEHELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEERE------------ 676
Query: 234 PALRTLTNDYNGLKRQVRGFPLLLQEA 260
TL N L+ Q+ LL++EA
Sbjct: 677 ---ATLNNSLMRLREQIVKANLLVREA 700
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 206 bits (524), Expect = 6e-53
Identities = 140/347 (40%), Positives = 201/347 (57%), Gaps = 26/347 (7%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLH-KGKPVSFELDKVF------- 357
+++V RVRP + +A V+ + SII+ K P SF D +
Sbjct: 5 SVKVAVRVRPFNARE-TSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTE 63
Query: 358 SPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE--NPGINQRAL 413
PQ ASQQ V++++ + ++ +G+NVCIFAYGQTGAGK+YTM G E GI +
Sbjct: 64 DPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLC 123
Query: 414 QLLFSEVQEKAS-DWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGL 472
+ LFS V E S Y++ VS EIY E +RDLL + + L +R P YV L
Sbjct: 124 EDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGP--YVQDL 181
Query: 473 TEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTGLRT--T 528
++ V S DI + + G+ RT TN+NE SSRSHA+ ++ T R D TGL +
Sbjct: 182 SKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKV 241
Query: 529 GKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQG------HVPFR 582
K++LVDLAGSER SGA G RL+E +INKSL+ LG VI+AL Q +P+R
Sbjct: 242 SKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYR 301
Query: 583 NSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 629
+S LT+LL+++L G+S+T M+ +SP + N ETL +L++A+R + +
Sbjct: 302 DSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQI 348
Score = 34.3 bits (77), Expect = 0.39
Identities = 42/188 (22%), Positives = 81/188 (43%), Gaps = 15/188 (7%)
Query: 15 EAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMA-ESKGMLSELNLEVQQKTDRL 73
+A L+ R P P P E + ++ L Q +++ E + L +L + +++ +
Sbjct: 602 QARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEE- 660
Query: 74 AEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPP--VKYVIKTVEVESSKTKQ 131
A++ L + A+ ++ R +S I+SLR Q PP V+ ++K + SS ++
Sbjct: 661 ADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREQLPPTTVQTIVKRCGLPSSGKRR 720
Query: 132 A---------LSESQARNQHLQEQVAMQRQVLKEM--EQQLQSSHQLTARLRAQIAMYES 180
A Q ++ ++ Q +KE+ E L A + A A+
Sbjct: 721 APRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMR 780
Query: 181 ELERAHGQ 188
EL R +G+
Sbjct: 781 ELCRTYGK 788
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 203 bits (516), Expect = 5e-52
Identities = 133/345 (38%), Positives = 191/345 (55%), Gaps = 24/345 (6%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSII----HLLHKGKPVSFELDKVFSPQA 361
NI+V+ R RP + + A + V D + L K ++ D VF
Sbjct: 18 NIQVVVRCRPFNLAERKA-SAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGAST 76
Query: 362 SQQDVFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEGTA---------ENP--GIN 409
Q DV++ V ++ I G+N IFAYGQTG GKT+TMEG E+P GI
Sbjct: 77 KQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGII 136
Query: 410 QRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLG--KEPQEKLEIRLCPDGSGQL 467
R L +F ++ + + E+++ VS EIYNE L DLL + E+L++ P +
Sbjct: 137 PRTLHQIFEKLTDNGT--EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGV 194
Query: 468 YVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTG--- 524
+ GL E V + D++ ++ E G RTT T +N +SSRSH++ VT+ + +
Sbjct: 195 IIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEE 254
Query: 525 LRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNS 584
L GKLNLVDLAGSE +G+SGA R REA +IN+SL LG VI AL R HVP+R S
Sbjct: 255 LVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRES 314
Query: 585 KLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 629
KLT +LQDSL G ++T ++ +SP N ETL +L++A R +++
Sbjct: 315 KLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNI 359
Score = 30.8 bits (68), Expect = 4.4
Identities = 48/250 (19%), Positives = 104/250 (41%), Gaps = 37/250 (14%)
Query: 35 SQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERL 94
S +Q+ + + + Q AESK +L EL + KTD L+ +E+ L
Sbjct: 597 STHVSQIFNMILKEQSLAAESKTVLQELINVL--KTDLLSSLEMILSP------------ 642
Query: 95 SRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQV-AMQRQV 153
T+ S+ + +K++ KT + K + E L + +Q
Sbjct: 643 ---------TVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENT 693
Query: 154 LKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV 213
+ + + + LT L+ +++ H Q L ++ +L ++ A+EE Q
Sbjct: 694 ICSLVESQKQCGNLTEDLKT--------IKQTHSQELCKLMNLWTERFCALEEKCENIQK 745
Query: 214 EMKAVHENLAGVRTNLLT-LQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAI 272
+ +V EN+ +++ + + D +G +++R F QE + V+ + +
Sbjct: 746 PLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFN---QEGTKLVEESVKHS- 801
Query: 273 EEVNSNNQEL 282
+++N N +++
Sbjct: 802 DKLNGNLEKI 811
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 203 bits (516), Expect = 5e-52
Identities = 119/294 (40%), Positives = 178/294 (60%), Gaps = 11/294 (3%)
Query: 345 KGKPVSFELDKVFSPQASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTA 403
KGK ++F D+VF A+QQDVFQ +++ S + G+N +FAYG TGAGKT+TM G
Sbjct: 64 KGKDLTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGRE 123
Query: 404 ENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDG 463
+PGI L+ ++ + + + + +S E+YNE + DLL EP+ L IR PD
Sbjct: 124 GDPGIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLL--EPKGPLAIREDPDK 181
Query: 464 SGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCST 523
+ V GL+ Q S + + ++ G+ NRT T+ N SSRSHA+ + V+ D
Sbjct: 182 G--VVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVP 239
Query: 524 GLR---TTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL---RSRQG 577
GL K++L+DLAGSER + A+G RLRE +IN+SL AL +V+ AL + R+
Sbjct: 240 GLTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKT 299
Query: 578 HVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVEL 631
HVP+R+SKLT LL+DSL G+ +T+M+ +SP +T +LK+A+R + + L
Sbjct: 300 HVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRL 353
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 202 bits (514), Expect = 8e-52
Identities = 130/358 (36%), Positives = 203/358 (56%), Gaps = 36/358 (10%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLL---------HKGKPVSFELDKV 356
+++V RVRP+ + + + EA + + +I +L + + +F D
Sbjct: 3 SVKVAVRVRPMNRREKD-LEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
Query: 357 F------SPQ-ASQQDVFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGI 408
F SP SQ+ VF+ + +V S +G+N C+FAYGQTG+GK+YTM G + + G+
Sbjct: 62 FYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGL 121
Query: 409 NQRALQLLFSEVQEKASDWE---YTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSG 465
R + LFS + E + W+ + VS EIYNE +RDLL ++ + +R+
Sbjct: 122 IPRICEGLFSRINE-TTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKE 180
Query: 466 QLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIV--TVRGVDCST 523
YV L++ VQ+ D+ ++ + G+ NRTT T +N+ SSRSHA+ + T D
Sbjct: 181 GPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEM 240
Query: 524 GLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL----------- 572
T K++LVDLAGSER +GA G RL+E +INKSL LG+VI+AL
Sbjct: 241 PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL 300
Query: 573 -RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 629
+ +Q VP+R+S LT+LL+DSL G+SKT+M+ +SP + N ETL +L++A R +++
Sbjct: 301 AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNI 358
Score = 52.4 bits (124), Expect = 1e-06
Identities = 70/339 (20%), Positives = 140/339 (41%), Gaps = 33/339 (9%)
Query: 34 HSQESAQLRDKLSQLQLEMAESKGMLSELNL---EVQQKTDRLAEVELRLKDCLAEKAQE 90
H +E+A+LR+K G+LS +L ++ + + L+ V L E+ Q
Sbjct: 553 HPKEAAKLREK---------RKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQR 603
Query: 91 EERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQ 150
EE E + S R ++ K+ + E + +Q + + + +Q Q+ Q
Sbjct: 604 EEL---------EKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQ 654
Query: 151 RQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFAR 210
+ LK + S + +L+ +A E E+ + L E Q +E K R EE F R
Sbjct: 655 EESLK------RRSFHIENKLKDLLA----EKEKFEEERLREQQEIELQKKRQEEETFLR 704
Query: 211 AQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQ 270
Q E++ + E + + L L + + ++ L+E + +
Sbjct: 705 VQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAH 764
Query: 271 AIEEVNSNNQELLRKYRR-ELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNA 329
+EE QE+++ RR E+Q ++ +L ++ ++ + R EDGE E
Sbjct: 765 -LEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQL 823
Query: 330 VTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQ 368
F+ ++ L++ K + + D + +Q++ +
Sbjct: 824 RFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILE 862
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/280 (24%), Positives = 121/280 (43%), Gaps = 42/280 (15%)
Query: 1 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 60
M+ N L E ++ E EL++L +K E Q+S + + Q ++E + +
Sbjct: 590 MLYNPGLEFERQQRE-ELEKLESKRK-LIEEMEEKQKSDKAELERMQQEVETQRKETEIV 647
Query: 61 ELNLEVQQKT--DRLAEVELRLKDCLAEKAQ-EEERLS-------RRLRDSHETIASLRA 110
+L + Q+++ R +E +LKD LAEK + EEERL ++ R ET ++
Sbjct: 648 QLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQE 707
Query: 111 QSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTAR 170
+ +K + + E + Q L + Q + EQ A K +E+Q + L A
Sbjct: 708 ELQRLKELNNNEKAEKFQIFQELDQLQ---KEKDEQYAKLELEKKRLEEQEKEQVMLVAH 764
Query: 171 LRAQIAMYESELERAHGQMLE--EMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTN 228
L Q+ + + Q+L E+Q +EE+K +L G+R +
Sbjct: 765 LEEQLREKQEMI-----QLLRRGEVQWVEEEK-------------------RDLEGIRES 800
Query: 229 LLTLQPALRTLTNDYNGL-KRQVRGFPLLLQEALRSVKAE 267
LL ++ A D L K Q+R F ++ ++ V E
Sbjct: 801 LLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLE 840
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 201 bits (511), Expect = 2e-51
Identities = 124/341 (36%), Positives = 193/341 (56%), Gaps = 22/341 (6%)
Query: 307 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHL-----------LHKGKPVSFELDK 355
+ V RVRP++ + E E + D+ ++ + H+ + S+ D
Sbjct: 12 LMVALRVRPISVAELE--EGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDV 69
Query: 356 VFSPQASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQ 414
F A+Q+ V+Q ++L+ I G+N +FAYG TG GKTYTM GT + PGI + L
Sbjct: 70 AFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEPGIYVQTLN 129
Query: 415 LLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTE 474
LF ++E ++D EY +++S EIYNE++RDLL LE+R D G + V G+TE
Sbjct: 130 DLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPS-LGYLELR--EDSKGVIQVAGITE 186
Query: 475 FQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLR---TTGKL 531
+ +I ++ G+ RT E T N+ SSRSHA+L VTVR + G+L
Sbjct: 187 VSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQGRL 246
Query: 532 NLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL--RSRQGHVPFRNSKLTYL 589
++DLAGSER ++ G R++E HIN+SL ALG+ I AL + ++ +R+SKLT L
Sbjct: 247 FMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLTRL 306
Query: 590 LQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVE 630
L+DSL G+S+T+M+ +SP E+ +L +A R ++++
Sbjct: 307 LKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIK 347
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 201 bits (510), Expect = 2e-51
Identities = 127/347 (36%), Positives = 187/347 (53%), Gaps = 27/347 (7%)
Query: 307 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDV 366
++V R+RP+ ++ II G+ F D VF ++Q +V
Sbjct: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVII-----GRDRVFTFDFVFGKNSTQDEV 60
Query: 367 FQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG------TAENPGINQRALQLLFSE 419
+ ++ LV S I+G+N +FAYGQTG+GKTYT+ G GI RA+Q +F
Sbjct: 61 YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS 120
Query: 420 VQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQS 479
+ E S ++ + VS E+Y E LRDLL E K ++ + D G + G E V+S
Sbjct: 121 ISEHPSI-DFNVKVSYIEVYKEDLRDLLELETSMK-DLHIREDEKGNTVIVGAKECHVES 178
Query: 480 VDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTG---------- 529
++ + E G+ R T T +NEHSSRSHA+ +++ V + G
Sbjct: 179 AGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVS 238
Query: 530 KLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL---RSRQGHVPFRNSKL 586
K + VDLAGSERV K+G G R +E+ IN L ALG+VI+AL R + H+P+R++K+
Sbjct: 239 KFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKI 298
Query: 587 TYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGP 633
T LL+DSL G +KT+M+ VSP N E+L SLK+A R R++ P
Sbjct: 299 TRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKP 345
Score = 38.9 bits (89), Expect = 0.016
Identities = 74/321 (23%), Positives = 141/321 (43%), Gaps = 42/321 (13%)
Query: 33 EHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQ-QKTDRLAEVELRLKDCLAEKAQEE 91
EH E A++ +Q QL+ E+K LS++ ++V+ QK R +L+ + +K Q++
Sbjct: 765 EHDAEQAKVELIETQKQLQELENKD-LSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQD 823
Query: 92 ERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQR 151
+ L +E A+ QS + ++ + + ++ L E + + L + +
Sbjct: 824 SKKLASLSIQNEKRANELEQS------VDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQ 877
Query: 152 QVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQM--LEEMQSLEEDKNRAIEEA-- 207
Q +KE+ QL++ + + +A+ + L+R G ++ +Q L+E K EE
Sbjct: 878 QKIKEI--QLKTGQEEGLKPKAE-DLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEK 934
Query: 208 -------FARAQVEMK----------AVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQV 250
+ ++K A+ + + + L AL T + LK
Sbjct: 935 VLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNT-----DSLKIST 989
Query: 251 RGFPLLLQE-ALRSVKAEIGQAIEEVNSNNQ-ELLRKYRRELQLRKKCHNELVRLKGNIR 308
R LL QE + ++V+ + A E+ + Q E+L+K + +LQ R+ HN +LK
Sbjct: 990 R-LNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRR--HNVDEKLKNGRV 1046
Query: 309 VIARVRPVTKEDGEGPEATNA 329
+ V + EG EA A
Sbjct: 1047 LSPEEEHVLFQLEEGIEALEA 1067
Score = 35.0 bits (79), Expect = 0.23
Identities = 58/321 (18%), Positives = 132/321 (41%), Gaps = 46/321 (14%)
Query: 5 ERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGM----LS 60
E+ + E+ + +LQEL K Q+ + + ++L++++ + K L+
Sbjct: 769 EQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLA 828
Query: 61 ELNL-------EVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLR---A 110
L++ E++Q D + +++L+ L E+ ++ ++L ++ + I ++
Sbjct: 829 SLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTG 888
Query: 111 QSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQ----------VAMQRQVLKEMEQQ 160
Q +K + ++ + K ++ S Q L EQ V QRQ L+E+E
Sbjct: 889 QEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEAD 948
Query: 161 LQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEED------KNRAIEEAFARAQVE 214
L+ + ++ A + E + L Q+L D + +E+ + V+
Sbjct: 949 LKKREAIVSKKEALL----QEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQ 1004
Query: 215 MK-AVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLL----------LQEALRS 263
++ + E + + LQ L + + +++ +L L+E + +
Sbjct: 1005 LQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEA 1064
Query: 264 VKAEIGQAIEEVNSNNQELLR 284
++A I E + N Q+ LR
Sbjct: 1065 LEAAIEYRNESI-QNRQKSLR 1084
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 200 bits (509), Expect = 3e-51
Identities = 132/348 (37%), Positives = 204/348 (58%), Gaps = 26/348 (7%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLH-KGKPVSFELDKVF----SPQ 360
+++V RVRP + E+ + + SII+ + K P SF D + SP+
Sbjct: 5 SVKVAVRVRPFNSRE-TSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPE 63
Query: 361 ----ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP--GINQRAL 413
ASQ V+ ++ + ++ +G+NVCIFAYGQTGAGK+YTM G E GI +
Sbjct: 64 DPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLC 123
Query: 414 QLLFSEVQEKASD-WEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGL 472
+ LF ++ + ++ Y++ VS EIY E +RDLL + + L +R P YV L
Sbjct: 124 EELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGP--YVEDL 181
Query: 473 TEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTGLRT--T 528
++ V S DI + + G+ RT TN+NE SSRSHA+ ++ T + D T L T
Sbjct: 182 SKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKV 241
Query: 529 GKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL------RSRQGHVPFR 582
K++LVDLAGSER +GA+G+RL+E +INKSL+ LG VI+AL + + +P+R
Sbjct: 242 SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYR 301
Query: 583 NSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVE 630
+S LT+LL+++L G+S+T MV +SP + N ETL +L++A+R + ++
Sbjct: 302 DSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIK 349
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 200 bits (509), Expect = 3e-51
Identities = 132/348 (37%), Positives = 204/348 (58%), Gaps = 26/348 (7%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLH-KGKPVSFELDKVF----SPQ 360
+++V RVRP + E+ + + SII+ + K P SF D + SP+
Sbjct: 5 SVKVAVRVRPFNSRE-TSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPE 63
Query: 361 ----ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP--GINQRAL 413
ASQ V+ ++ + ++ +G+NVCIFAYGQTGAGK+YTM G E GI +
Sbjct: 64 DPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLC 123
Query: 414 QLLFSEVQEKASD-WEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGL 472
+ LF ++ + ++ Y++ VS EIY E +RDLL + + L +R P YV L
Sbjct: 124 EELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGP--YVEDL 181
Query: 473 TEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTGLRT--T 528
++ V S DI + + G+ RT TN+NE SSRSHA+ ++ T + D T L T
Sbjct: 182 SKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKV 241
Query: 529 GKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL------RSRQGHVPFR 582
K++LVDLAGSER +GA+G+RL+E +INKSL+ LG VI+AL + + +P+R
Sbjct: 242 SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYR 301
Query: 583 NSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVE 630
+S LT+LL+++L G+S+T MV +SP + N ETL +L++A+R + ++
Sbjct: 302 DSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIK 349
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 199 bits (506), Expect = 7e-51
Identities = 131/353 (37%), Positives = 204/353 (57%), Gaps = 32/353 (9%)
Query: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLH-KGKPVSFELDKVF----SPQ 360
+++V RVRP + ++ + +I++ K P SF D + SP+
Sbjct: 5 SVKVAVRVRPFNSRE-MSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPE 63
Query: 361 ----ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP--GINQRAL 413
ASQ+ V++++ + ++ +G+NVCIFAYGQTGAGK+YTM G E GI +
Sbjct: 64 DINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLC 123
Query: 414 QLLFSEVQEKASD-WEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGL 472
+ LFS + + +D Y++ VS EIY E +RDLL + + L +R P YV L
Sbjct: 124 EDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGP--YVEDL 181
Query: 473 TEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTGLRT--T 528
++ V S +DI + + G+ RT TN+NE SSRSHA+ +I T + D T + T
Sbjct: 182 SKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKV 241
Query: 529 GKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL------------RSRQ 576
K++LVDLAGSER +GA+G+RL+E +INKSL+ LG VI+AL + +
Sbjct: 242 SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKT 301
Query: 577 GHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 629
+P+R+S LT+LL+++L G+S+T MV +SP + N ETL +L++A+R + +
Sbjct: 302 DFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQI 354
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 196 bits (498), Expect = 6e-50
Identities = 134/361 (37%), Positives = 203/361 (56%), Gaps = 43/361 (11%)
Query: 287 RRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKG 346
RREL+L KC +V ++GN V+ TK+ P A +
Sbjct: 17 RRELELNTKC---VVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDY-------------- 59
Query: 347 KPVSFELDKVFSPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE 404
+ +D+ + + A Q+ VF+ + + ++ G+N CIFAYGQTG+GK+++M G AE
Sbjct: 60 --CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117
Query: 405 NPGINQRALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR---- 458
G+ R LF + E+ + + VS EIYNE +RDLL K ++ L++R
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177
Query: 459 LCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTV 516
L P YV GL++ V S +DI + G+ +RT TN+NE SSRSHA+ +I+T
Sbjct: 178 LGP------YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231
Query: 517 RGVDCSTGL--RTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-- 572
D +G K++LVDLAGSERV K+GA G RL+E +INKSL+ LG VI++L
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 573 ----RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 628
+ + VP+R+S LT+LL+D+L G+S+T M+ +SP N ETL +L++A+R +
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 629 V 629
+
Sbjct: 352 I 352
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 13/147 (8%)
Query: 103 ETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQ 162
E I + PV+ V++ +E KQ L E ++ L+EQ M + L+++ QQL
Sbjct: 586 EVIMKTLNSNDPVQNVVQVLE------KQYLEEKRSA---LEEQRLMYERELEQLRQQLS 636
Query: 163 SSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV---EMKAVH 219
Q + ++A ++ Q EE L + E +A E +
Sbjct: 637 PDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLA 696
Query: 220 ENLAGVRTNLLTLQ-PALRTLTNDYNG 245
E ++ + +TLQ PA N G
Sbjct: 697 EEMSKLTDYQVTLQIPAANLSANRKRG 723
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 196 bits (498), Expect = 6e-50
Identities = 134/361 (37%), Positives = 203/361 (56%), Gaps = 43/361 (11%)
Query: 287 RRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKG 346
RREL+L KC +V ++GN V+ TK+ P A +
Sbjct: 17 RRELELNTKC---VVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDY-------------- 59
Query: 347 KPVSFELDKVFSPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE 404
+ +D+ + + A Q+ VF+ + + ++ G+N CIFAYGQTG+GK+++M G AE
Sbjct: 60 --CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117
Query: 405 NPGINQRALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR---- 458
G+ R LF + E+ + + VS EIYNE +RDLL K ++ L++R
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177
Query: 459 LCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTV 516
L P YV GL++ V S +DI + G+ +RT TN+NE SSRSHA+ +I+T
Sbjct: 178 LGP------YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231
Query: 517 RGVDCSTGL--RTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-- 572
D +G K++LVDLAGSERV K+GA G RL+E +INKSL+ LG VI++L
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 573 ----RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 628
+ + VP+R+S LT+LL+D+L G+S+T M+ +SP N ETL +L++A+R +
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 629 V 629
+
Sbjct: 352 I 352
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 13/147 (8%)
Query: 103 ETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQ 162
E I + PV+ V++ +E KQ L E ++ L+EQ M + L+++ QQL
Sbjct: 586 EVIMKTLNSNDPVQNVVQVLE------KQYLEEKRSA---LEEQRLMYERELEQLRQQLS 636
Query: 163 SSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV---EMKAVH 219
Q + ++A ++ Q EE L + E +A E +
Sbjct: 637 PDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLA 696
Query: 220 ENLAGVRTNLLTLQ-PALRTLTNDYNG 245
E ++ + +TLQ PA N G
Sbjct: 697 EEMSKLTDYQVTLQIPAANLSANRKRG 723
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 196 bits (498), Expect = 6e-50
Identities = 134/361 (37%), Positives = 203/361 (56%), Gaps = 43/361 (11%)
Query: 287 RRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKG 346
RREL+L KC +V ++GN V+ TK+ P A +
Sbjct: 17 RRELELNTKC---VVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDY-------------- 59
Query: 347 KPVSFELDKVFSPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE 404
+ +D+ + + A Q+ VF+ + + ++ G+N CIFAYGQTG+GK+++M G AE
Sbjct: 60 --CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117
Query: 405 NPGINQRALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR---- 458
G+ R LF + E+ + + VS EIYNE +RDLL K ++ L++R
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177
Query: 459 LCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTV 516
L P YV GL++ V S +DI + G+ +RT TN+NE SSRSHA+ +I+T
Sbjct: 178 LGP------YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231
Query: 517 RGVDCSTGL--RTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-- 572
D +G K++LVDLAGSERV K+GA G RL+E +INKSL+ LG VI++L
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 573 ----RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 628
+ + VP+R+S LT+LL+D+L G+S+T M+ +SP N ETL +L++A+R +
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 629 V 629
+
Sbjct: 352 I 352
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 13/147 (8%)
Query: 103 ETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQ 162
E I + PV+ V++ +E KQ L E ++ L+EQ M + L+++ QQL
Sbjct: 586 EVIMKTLNSNDPVQNVVQVLE------KQYLEEKRSA---LEEQRLMYERELEQLRQQLS 636
Query: 163 SSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV---EMKAVH 219
Q + ++A ++ Q EE L + E +A E +
Sbjct: 637 PDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLA 696
Query: 220 ENLAGVRTNLLTLQ-PALRTLTNDYNG 245
E ++ + +TLQ PA N G
Sbjct: 697 EEMSKLTDYQVTLQIPAANLSANRKRG 723
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 196 bits (498), Expect = 6e-50
Identities = 134/361 (37%), Positives = 203/361 (56%), Gaps = 43/361 (11%)
Query: 287 RRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKG 346
RREL+L KC +V ++GN V+ TK+ P A +
Sbjct: 17 RRELELNTKC---VVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDY-------------- 59
Query: 347 KPVSFELDKVFSPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE 404
+ +D+ + + A Q+ VF+ + + ++ G+N CIFAYGQTG+GK+++M G AE
Sbjct: 60 --CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117
Query: 405 NPGINQRALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR---- 458
G+ R LF + E+ + + VS EIYNE +RDLL K ++ L++R
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177
Query: 459 LCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTV 516
L P YV GL++ V S +DI + G+ +RT TN+NE SSRSHA+ +I+T
Sbjct: 178 LGP------YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231
Query: 517 RGVDCSTGL--RTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-- 572
D +G K++LVDLAGSERV K+GA G RL+E +INKSL+ LG VI++L
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 573 ----RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 628
+ + VP+R+S LT+LL+D+L G+S+T M+ +SP N ETL +L++A+R +
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 629 V 629
+
Sbjct: 352 I 352
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 13/147 (8%)
Query: 103 ETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQ 162
E I + PV+ V++ +E KQ L E ++ L+EQ M + L+++ QQL
Sbjct: 586 EVIMKTLNSNDPVQNVVQVLE------KQYLEEKRSA---LEEQRLMYERELEQLRQQLS 636
Query: 163 SSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV---EMKAVH 219
Q + ++A ++ Q EE L + E +A E +
Sbjct: 637 PDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLA 696
Query: 220 ENLAGVRTNLLTLQ-PALRTLTNDYNG 245
E ++ + +TLQ PA N G
Sbjct: 697 EEMSKLTDYQVTLQIPAANLSANRKRG 723
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 194 bits (492), Expect = 3e-49
Identities = 183/642 (28%), Positives = 298/642 (46%), Gaps = 56/642 (8%)
Query: 25 PAGPCPGCEHSQESAQLRDKLSQL---QLEMAESKGMLSELNLEVQQKTD-----RLAEV 76
P P P + + R+K S L +LE K + L L+ + KTD + AE+
Sbjct: 79 PLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLTLQRRAKTDSAEKWKTAEI 138
Query: 77 ELRLKDCLAEKAQEEERLSRRLRDSHETIASLR----AQSPPVKYVIKTVEVESSKT-KQ 131
+ E +S+ R + + + + A S P+ + +E+ + K K+
Sbjct: 139 DSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVPLDEDPQVIEMMADKKYKE 198
Query: 132 ALSESQARNQHLQEQVAMQRQVLKEMEQQ--LQSSHQLTARLRAQIAMYESELERAHGQM 189
S N+++ + + R + + Q ++S H T ++++ + + +
Sbjct: 199 TFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPTQSKLDIKVLGTGNLYHRS 258
Query: 190 LEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQ-PALRTLTNDYNGLKR 248
+ + + +K ++E+ + K E+ + +L L+ PA L N + L+
Sbjct: 259 IGKEIAKTSNKFGSLEK-----RTPTKCTTEHKLTTKCSLPQLKSPAPSILKNRMSNLQV 313
Query: 249 QVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIR 308
+ R L A ++ S +L + +Q + L +
Sbjct: 314 KQRPKSSFL-------------ANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 360
Query: 309 VIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGK-----PVSF-ELDKVFSPQAS 362
V RVRP TK + + +A+ V + ++ H K VSF D+ AS
Sbjct: 361 VAVRVRPFTKRE-KIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYAS 419
Query: 363 QQDVFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQ 421
Q V++++ A L+ +GFN C+FAYGQTG+GK+YTM G +E PGI R + LFS+V
Sbjct: 420 QTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVA 479
Query: 422 EK-ASDWEYTITVSAAEIYNEVLRDLL---GKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 477
K + Y I +S E+YNE + DLL + Q K +R+ YV L+ V
Sbjct: 480 RKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIV 539
Query: 478 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTG----LRTTGKL 531
S DI E G+ R T T +N+ SSRSH++ L++T + G R T ++
Sbjct: 540 SSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRI 599
Query: 532 NLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL----RSRQGHVPFRNSKLT 587
NL+DLAGSER + G RL+E INKSL LG VI+AL R +P+R S LT
Sbjct: 600 NLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLT 659
Query: 588 YLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 629
+LL++SL G+SKT M+ +SP N ETL +L++A + R +
Sbjct: 660 WLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLI 701
Score = 37.4 bits (85), Expect = 0.047
Identities = 35/164 (21%), Positives = 73/164 (44%), Gaps = 22/164 (13%)
Query: 3 ENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQL--EMAESKGMLS 60
+NE L + + EAE++E + K E + Q+ +++Q +L + A + +
Sbjct: 928 KNELLMAQRSQLEAEIKEAQLKAK------EEMMQGIQIAKEMAQQELSSQKAAYESKIK 981
Query: 61 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 120
L E+++++ R E+ + K +E E+ + L + K
Sbjct: 982 ALEAELREESQRKKMQEINNQKA-NHKIEELEKAKQHLEQE-------------IYVNKK 1027
Query: 121 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSS 164
+E+E+ TKQAL + R+ + E + ++Q + + Q LQ +
Sbjct: 1028 RLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN 1071
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,052,684
Number of Sequences: 37866
Number of extensions: 1039488
Number of successful extensions: 8953
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 282
Number of HSP's successfully gapped in prelim test: 727
Number of HSP's that attempted gapping in prelim test: 4891
Number of HSP's gapped (non-prelim): 2858
length of query: 687
length of database: 18,247,518
effective HSP length: 109
effective length of query: 578
effective length of database: 14,120,124
effective search space: 8161431672
effective search space used: 8161431672
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.