Search of human proteins with 194097377

Search of human proteins with 194097377

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens]
         (272 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens]        546   e-156
gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens]        419   e-117
gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]      213   1e-55
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]      213   1e-55
gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]      213   1e-55
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ...    61   1e-09
gi|157743284 ankyrin repeat domain 52 [Homo sapiens]                   57   2e-08
gi|62988328 ankyrin repeat domain 50 [Homo sapiens]                    56   4e-08
gi|34577122 nuclear factor kappa-B, subunit 1 [Homo sapiens]           54   1e-07
gi|121582655 ankyrin repeat domain 35 [Homo sapiens]                   54   1e-07
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    53   2e-07
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi...    53   3e-07
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]                    52   4e-07
gi|157504499 ankyrin repeat domain 47 [Homo sapiens]                   52   4e-07
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo...    52   7e-07
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         51   9e-07
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         51   9e-07
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         51   9e-07
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         51   9e-07
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         51   9e-07
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         51   9e-07
gi|39812133 ankyrin repeat domain 2 isoform a [Homo sapiens]           51   9e-07
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]        50   2e-06
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo...    50   2e-06
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is...    50   2e-06
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    50   2e-06
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled...    50   2e-06
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                   50   2e-06
gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3 ...    50   2e-06
gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2 ...    50   2e-06

>gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens]
          Length = 272

 Score =  546 bits (1407), Expect = e-156
 Identities = 272/272 (100%), Positives = 272/272 (100%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER
Sbjct: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ
Sbjct: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120

Query: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180
           LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL
Sbjct: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180

Query: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA 240
           DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA
Sbjct: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA 240

Query: 241 IPGAQDREEETGGGGQNGTEVGEDGIGQAGNR 272
           IPGAQDREEETGGGGQNGTEVGEDGIGQAGNR
Sbjct: 241 IPGAQDREEETGGGGQNGTEVGEDGIGQAGNR 272


>gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens]
          Length = 452

 Score =  419 bits (1076), Expect = e-117
 Identities = 216/238 (90%), Positives = 217/238 (91%), Gaps = 11/238 (4%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER
Sbjct: 136 MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 195

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           RDQRGLTALMKAAMRNRC          ADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ
Sbjct: 196 RDQRGLTALMKAAMRNRC----------ADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 245

Query: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180
           LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL
Sbjct: 246 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 305

Query: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSS 238
           DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELL  A       P+S P S
Sbjct: 306 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPL-VPQSPPGS 362


>gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 494

 Score =  213 bits (542), Expect = 1e-55
 Identities = 117/271 (43%), Positives = 156/271 (57%), Gaps = 14/271 (5%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           +VACYHGF   V  L+ CP +DVN QD  G+TAL+ AAQAGH  + + LLNY+ GLDLER
Sbjct: 126 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 185

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           R+  G TALMKAAM+ R +C+  L++AGAD+ A DP RG +  EWA  T   D V  +++
Sbjct: 186 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 245

Query: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180
           LL RP  EQ  + Y+PE P       +          L + + + L+      P++GGVL
Sbjct: 246 LLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVL 305

Query: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA 240
           DH+V  TTSL SP V   C T+CP+ PPS+G R  +V E+L    A+             
Sbjct: 306 DHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARG------------ 353

Query: 241 IPGAQDREEETGGGGQNGTEVGEDGIGQAGN 271
            P AQ+ E+E GG GQ G    ED   + G+
Sbjct: 354 -PQAQE-EDEVGGAGQRGRTGQEDADSREGS 382


>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 1006

 Score =  213 bits (542), Expect = 1e-55
 Identities = 117/271 (43%), Positives = 156/271 (57%), Gaps = 14/271 (5%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           +VACYHGF   V  L+ CP +DVN QD  G+TAL+ AAQAGH  + + LLNY+ GLDLER
Sbjct: 638 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 697

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           R+  G TALMKAAM+ R +C+  L++AGAD+ A DP RG +  EWA  T   D V  +++
Sbjct: 698 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 757

Query: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180
           LL RP  EQ  + Y+PE P       +          L + + + L+      P++GGVL
Sbjct: 758 LLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVL 817

Query: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA 240
           DH+V  TTSL SP V   C T+CP+ PPS+G R  +V E+L    A+             
Sbjct: 818 DHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARG------------ 865

Query: 241 IPGAQDREEETGGGGQNGTEVGEDGIGQAGN 271
            P AQ+ E+E GG GQ G    ED   + G+
Sbjct: 866 -PQAQE-EDEVGGAGQRGRTGQEDADSREGS 894


>gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 494

 Score =  213 bits (542), Expect = 1e-55
 Identities = 117/271 (43%), Positives = 156/271 (57%), Gaps = 14/271 (5%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           +VACYHGF   V  L+ CP +DVN QD  G+TAL+ AAQAGH  + + LLNY+ GLDLER
Sbjct: 126 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 185

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           R+  G TALMKAAM+ R +C+  L++AGAD+ A DP RG +  EWA  T   D V  +++
Sbjct: 186 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 245

Query: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180
           LL RP  EQ  + Y+PE P       +          L + + + L+      P++GGVL
Sbjct: 246 LLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVL 305

Query: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA 240
           DH+V  TTSL SP V   C T+CP+ PPS+G R  +V E+L    A+             
Sbjct: 306 DHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARG------------ 353

Query: 241 IPGAQDREEETGGGGQNGTEVGEDGIGQAGN 271
            P AQ+ E+E GG GQ G    ED   + G+
Sbjct: 354 -PQAQE-EDEVGGAGQRGRTGQEDADSREGS 382


>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
           sapiens]
          Length = 522

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 38/92 (41%), Positives = 57/92 (61%), Gaps = 3/92 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           D N +DK G+TAL LAA  GH+ ++  L++  +GLDLE ++  GLTAL  AA  +  +CV
Sbjct: 184 DHNVKDKEGNTALHLAAGRGHMAVLQRLVD--IGLDLEEQNAEGLTALHSAAGGSHPDCV 241

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAVLTDSFD 113
             LL AG+ + A+   +  + L +A L+ S D
Sbjct: 242 QLLLRAGSTVNALTQ-KNLSCLHYAALSGSED 272



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           ++ + K G T L  AAQ GHVP+++ ++     + L+  D+ G TA  +AA   + + + 
Sbjct: 117 IHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALD 176

Query: 83  TLLMAGADLTAVDPVRGKTALEWA 106
            L+ +G D    D   G TAL  A
Sbjct: 177 FLVGSGCDHNVKDK-EGNTALHLA 199



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 2   VACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
           +A  H F ++V LL +    DVN  D    T L LAA+     +  +LL    G+DL  R
Sbjct: 297 LAVRHNFPALVRLLINSDS-DVNAVDNRQQTPLHLAAEHAWQDIADMLL--IAGVDLNLR 353

Query: 62  DQRGLTALMKAAMRNRCECVATLLMA 87
           D++G TAL  A   N    V  ++ A
Sbjct: 354 DKQGKTALAVAVRSNHVSLVDMIIKA 379



 Score = 35.0 bits (79), Expect = 0.070
 Identities = 38/113 (33%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 3   ACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRD 62
           A   G + V  +L H      N  D  G + L LA +     LV LL+N     D+   D
Sbjct: 265 AALSGSEDVSRVLIHAGGC-ANVVDHQGASPLHLAVRHNFPALVRLLINS--DSDVNAVD 321

Query: 63  QRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTV 115
            R  T L  AA     +    LL+AG DL   D  +GKTAL  AV ++    V
Sbjct: 322 NRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDK-QGKTALAVAVRSNHVSLV 373



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 21  LDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           LD+ +Q+  G TAL  AA   H   V LLL    G  +    Q+ L+ L  AA+    + 
Sbjct: 216 LDLEEQNAEGLTALHSAAGGSHPDCVQLLLR--AGSTVNALTQKNLSCLHYAALSGSEDV 273

Query: 81  VATLLMAGADLTAVDPVRGKTALEWAV 107
              L+ AG     VD  +G + L  AV
Sbjct: 274 SRVLIHAGGCANVVDH-QGASPLHLAV 299



 Score = 32.0 bits (71), Expect = 0.59
 Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 5/88 (5%)

Query: 30  GDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATLLMAGA 89
           G  AL+L+A  GH+ ++ +L+N    +  E +D  GLT L  AA +     +A  +M   
Sbjct: 91  GMNALLLSAWFGHLRILQILVNSGAKIHCESKD--GLTLLHCAAQKGHVPVLA-FIMEDL 147

Query: 90  DLTAVDPV--RGKTALEWAVLTDSFDTV 115
           +  A+D V   G+TA   A      D +
Sbjct: 148 EDVALDHVDKLGRTAFHRAAEHGQLDAL 175



 Score = 32.0 bits (71), Expect = 0.59
 Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 27  DKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATLLM 86
           DK G TA   AA+ G +  +  L+    G D   +D+ G TAL  AA R     +  L+ 
Sbjct: 156 DKLGRTAFHRAAEHGQLDALDFLVGS--GCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 213

Query: 87  AGADLTAVDPVRGKTALEWA 106
            G DL   +   G TAL  A
Sbjct: 214 IGLDLEEQN-AEGLTALHSA 232


>gi|157743284 ankyrin repeat domain 52 [Homo sapiens]
          Length = 1076

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 40/107 (37%), Positives = 58/107 (54%), Gaps = 7/107 (6%)

Query: 10  SVVALLSHCPFL----DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRG 65
           S+V+ LS+   L    D+N  D  G T L  AA  G+V  ++LLL+   G DL RRD+ G
Sbjct: 399 SIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSS--GADLRRRDKFG 456

Query: 66  LTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSF 112
            T L  AA     +C  TL+ AGA +   D  +G + L +A  +D++
Sbjct: 457 RTPLHYAAANGSYQCAVTLVTAGAGVNEAD-CKGCSPLHYAAASDTY 502



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 31/80 (38%), Positives = 40/80 (50%), Gaps = 3/80 (3%)

Query: 27  DKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATLLM 86
           D  G T LMLA   GHV  V LLL    G   +  D RG TAL + A+    +C+A LL 
Sbjct: 685 DAYGQTPLMLAIMNGHVDCVHLLLE--KGSTADAADLRGRTALHRGAVTGCEDCLAALLD 742

Query: 87  AGADLTAVDPVRGKTALEWA 106
             A +   D  +G+T +  A
Sbjct: 743 HDAFVLCRD-FKGRTPIHLA 761



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 29/82 (35%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 34  LMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATLLMAGADLTA 93
           L LAA  GH   +  L    V LD+  RD +G TAL  A  R   ECV  L   GA    
Sbjct: 589 LHLAAYNGHCEALKTLAETLVNLDV--RDHKGRTALFLATERGSTECVEVLTAHGASALI 646

Query: 94  VDPVRGKTALEWAVLTDSFDTV 115
            +  R  T L  A  +   D++
Sbjct: 647 KERKRKWTPLHAAAASGHTDSL 668



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 33/85 (38%), Positives = 43/85 (50%), Gaps = 4/85 (4%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           VN +D  G T L  AA A +V  + +LL +    ++   D  G TALM AA   +   V 
Sbjct: 851 VNSRDAKGRTPLHAAAFADNVSGLRMLLQHQA--EVNATDHTGRTALMTAAENGQTAAVE 908

Query: 83  TLLMAG-ADLTAVDPVRGKTALEWA 106
            LL  G ADLT +D  +  TAL  A
Sbjct: 909 FLLYRGKADLTVLDENK-NTALHLA 932



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N  D+ G +AL  A  +GH+  V+LLLN   G  L   D++    L  AA     E + 
Sbjct: 133 LNVADRSGRSALHHAVHSGHLETVNLLLN--KGASLNVCDKKERQPLHWAAFLGHLEVLK 190

Query: 83  TLLMAGADLTAVD 95
            L+  GADL   D
Sbjct: 191 LLVARGADLGCKD 203



 Score = 36.2 bits (82), Expect = 0.031
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           +VN  D  G TALM AA+ G    V  LL Y    DL   D+   TAL  A  +   +C 
Sbjct: 883 EVNATDHTGRTALMTAAENGQTAAVEFLL-YRGKADLTVLDENKNTALHLACSKGHEKCA 941

Query: 82  ATLLMAGADLTAVD 95
             +L    DL  ++
Sbjct: 942 LMILAETQDLGLIN 955



 Score = 35.4 bits (80), Expect = 0.053
 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 2/74 (2%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           ++N  D+   T L  AA  G VP++ LLL    G ++  +D   LT L +AA     + +
Sbjct: 33  NINVLDQERRTPLHAAAYVGDVPILQLLL--MSGANVNAKDTLWLTPLHRAAASRNEKVL 90

Query: 82  ATLLMAGADLTAVD 95
             LL   AD+ A D
Sbjct: 91  GLLLAHSADVNARD 104



 Score = 34.7 bits (78), Expect = 0.091
 Identities = 36/140 (25%), Positives = 51/140 (36%), Gaps = 50/140 (35%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLL------------------------------- 50
           +++  DK G+T L +AA+ GH  L+S L+                               
Sbjct: 331 EIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRK 390

Query: 51  ---------------NYYV---GLDLERRDQRGLTALMKAAMRNRCECVATLLMAGADLT 92
                          N +V   G D+   D  G T L  AA     EC+  LL +GADL 
Sbjct: 391 LLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLR 450

Query: 93  AVDPVRGKTALEWAVLTDSF 112
             D   G+T L +A    S+
Sbjct: 451 RRDKF-GRTPLHYAAANGSY 469



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N  DK     L  AA  GH+ ++ LL+    G DL  +D++G   L  AA   + E V 
Sbjct: 166 LNVCDKKERQPLHWAAFLGHLEVLKLLVAR--GADLGCKDRKGYGLLHTAAASGQIEVVK 223

Query: 83  TLLMAGADLTAVDPVRGKTALEWA 106
            LL  GA++   +   G TAL  A
Sbjct: 224 YLLRMGAEIDEPNAF-GNTALHIA 246



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 34/114 (29%), Positives = 44/114 (38%), Gaps = 1/114 (0%)

Query: 1    MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
            M A  +G  + V  L +    D+   D+  +TAL LA   GH     ++L     L L  
Sbjct: 896  MTAAENGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLIN 955

Query: 61   RDQRGLTALMKAAMRN-RCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFD 113
                 L   +  A RN     V  LL  GA + AVD      AL  A   D  D
Sbjct: 956  ATNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVAD 1009



 Score = 32.3 bits (72), Expect = 0.45
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           DVN Q K G + L +AA  G      +L+    G +++  D+ G T L  AA       +
Sbjct: 298 DVNYQSKEGKSPLHMAAIHGRFTRSQILIQN--GSEIDCADKFGNTPLHVAARYGHELLI 355

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAVL 108
           +TL+  GAD TA   +     L  AVL
Sbjct: 356 STLMTNGAD-TARRGIHDMFPLHLAVL 381


>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
          Length = 1429

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 57/179 (31%), Positives = 85/179 (47%), Gaps = 21/179 (11%)

Query: 7   GFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGL 66
           G  SVV+LL      +V+  DK G T L++AA  GHV +V LLL    G D++  D  G 
Sbjct: 726 GHASVVSLLIDRG-AEVDHCDKDGMTPLLVAAYEGHVDVVDLLLE--GGADVDHTDNNGR 782

Query: 67  TALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQ 126
           T L+ AA       V TLL  GA + ++D   G+T L  A    + + V   R LL R  
Sbjct: 783 TPLLAAASMGHASVVNTLLFWGAAVDSIDS-EGRTVLSIASAQGNVEVV---RTLLDR-- 836

Query: 127 VEQLSQHYKPE--WPALSGLVAQAQAQAQVAPSLLERLQATLS------LPFAPSPQEG 177
              L ++++ +  W  L   +A  +    +  +L+E+   T        +PF  + QEG
Sbjct: 837 --GLDENHRDDAGWTPLH--MAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEG 891



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 42/118 (35%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 3   ACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRD 62
           A Y G   VV LL      D+  +D  G T L LAA+ GH  +V+ L+    G ++   D
Sbjct: 552 AAYSGSLDVVNLLVSRG-ADLEIEDAHGHTPLTLAARQGHTKVVNCLIG--CGANINHTD 608

Query: 63  QRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           Q G TAL  AA     E V+ LL AG  +   D    +TAL  A      D V  + Q
Sbjct: 609 QDGWTALRSAAWGGHTEVVSALLYAGVKVDCAD-ADSRTALRAAAWGGHEDIVLNLLQ 665



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 38/102 (37%), Positives = 50/102 (49%), Gaps = 4/102 (3%)

Query: 2   VACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
           +A   G   VV  L  C   ++N  D+ G TAL  AA  GH  +VS LL  Y G+ ++  
Sbjct: 584 LAARQGHTKVVNCLIGCG-ANINHTDQDGWTALRSAAWGGHTEVVSALL--YAGVKVDCA 640

Query: 62  DQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTAL 103
           D    TAL  AA     + V  LL  GA++   D   G+TAL
Sbjct: 641 DADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADN-EGRTAL 681



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 4/105 (3%)

Query: 2    VACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
            V+C+ G   +V +L      DVN  D    +AL  AA  GHV +V LL+ +  G  ++  
Sbjct: 985  VSCWQGHMEMVQVLI-AYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEH--GAVVDHT 1041

Query: 62   DQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWA 106
              +G TAL  AA     + V  LL  GAD    D   G+TA+  A
Sbjct: 1042 CNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF-GRTAMRVA 1085



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 3/84 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           VNQ D  G T L  AA +G + +V+LL++   G DLE  D  G T L  AA +   + V 
Sbjct: 538 VNQCDSNGRTLLANAAYSGSLDVVNLLVSR--GADLEIEDAHGHTPLTLAARQGHTKVVN 595

Query: 83  TLLMAGADLTAVDPVRGKTALEWA 106
            L+  GA++   D   G TAL  A
Sbjct: 596 CLIGCGANINHTDQ-DGWTALRSA 618



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 9/90 (10%)

Query: 3    ACYHGFQSVVALL-SHCPFLD--VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLE 59
            A + G   VV LL  H   +D   NQ    G TAL +AAQ GH+ +V +LL +  G D  
Sbjct: 1019 AAWQGHVKVVQLLIEHGAVVDHTCNQ----GATALCIAAQEGHIDVVQVLLEH--GADPN 1072

Query: 60   RRDQRGLTALMKAAMRNRCECVATLLMAGA 89
              DQ G TA+  AA     + +  L   GA
Sbjct: 1073 HADQFGRTAMRVAAKNGHSQIIKLLEKYGA 1102



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 39/119 (32%), Positives = 56/119 (47%), Gaps = 11/119 (9%)

Query: 3   ACYHGFQSVVA-LLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
           A + G + +V  LL H    +VN+ D  G TAL+ AA  GH  +V  LL++  G ++   
Sbjct: 651 AAWGGHEDIVLNLLQHGA--EVNKADNEGRTALIAAAYMGHREIVEHLLDH--GAEVNHE 706

Query: 62  DQRGLTALMKAAM-----RNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTV 115
           D  G TAL  AA+     +     V+ L+  GA++   D   G T L  A      D V
Sbjct: 707 DVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDK-DGMTPLLVAAYEGHVDVV 764



 Score = 36.6 bits (83), Expect = 0.024
 Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 2    VACYHGFQSVVALL-SHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
            VA   G + +V LL SH    DVN +D  G   L + A    + +    L    G ++E 
Sbjct: 919  VAALEGHRDIVELLFSHGA--DVNCKDADGRPTLYILALENQLTMAEYFLEN--GANVEA 974

Query: 61   RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVD 95
             D  G TAL  +  +   E V  L+   AD+ A D
Sbjct: 975  SDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAAD 1009



 Score = 35.8 bits (81), Expect = 0.041
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 7/96 (7%)

Query: 22   DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
            +V   D  G TAL ++   GH+ +V +L+ Y+   D+   D    +AL  AA +   + V
Sbjct: 971  NVEASDAEGRTALHVSCWQGHMEMVQVLIAYHA--DVNAADNEKRSALQSAAWQGHVKVV 1028

Query: 82   ATLLMAGADLTAVDPV--RGKTALEWAVLTDSFDTV 115
              L+  GA    VD    +G TAL  A      D V
Sbjct: 1029 QLLIEHGA---VVDHTCNQGATALCIAAQEGHIDVV 1061



 Score = 30.0 bits (66), Expect = 2.2
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 3/52 (5%)

Query: 2    VACYHGFQSVV-ALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNY 52
            +A   G   VV  LL H    D N  D+ G TA+ +AA+ GH  ++ LL  Y
Sbjct: 1051 IAAQEGHIDVVQVLLEHGA--DPNHADQFGRTAMRVAAKNGHSQIIKLLEKY 1100


>gi|34577122 nuclear factor kappa-B, subunit 1 [Homo sapiens]
          Length = 969

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 34/91 (37%), Positives = 53/91 (58%), Gaps = 1/91 (1%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYY-VGLDLERRDQRGLTALMKAAMRNRCEC 80
           D++  D+ G++ L LAA+ GH  ++S+LL +    L L+  +  GL A+  A M N   C
Sbjct: 608 DLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMMSNSLPC 667

Query: 81  VATLLMAGADLTAVDPVRGKTALEWAVLTDS 111
           +  L+ AGAD+ A +   G+TAL  AV  D+
Sbjct: 668 LLLLVAAGADVNAQEQKSGRTALHLAVEHDN 698



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 8/112 (7%)

Query: 26  QDKGGDTALMLAAQAGHVPLVSLLLNYYVGL----DLERRDQRGLTALMKAAMRNRCECV 81
           QD+ GD+ L LA    H  LV  LL    GL     +  R+    T L  A +  + + V
Sbjct: 540 QDENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVV 599

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQH 133
             LL AGADL+ +D + G + L  A   +  D V  I  LL+  +   L  H
Sbjct: 600 EDLLRAGADLSLLDRL-GNSVLHLAA-KEGHDKVLSI--LLKHKKAALLLDH 647



 Score = 31.6 bits (70), Expect = 0.77
 Identities = 29/71 (40%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 22  DVN-QQDKGGDTALMLAAQAGHVPLVS-LLLNYYVGLDLERRDQRGLTALMKAAMRNRCE 79
           DVN Q+ K G TAL LA +  ++ L   LLL     +D    D  G T L  AA R    
Sbjct: 677 DVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYD--GTTPLHIAAGRGSTR 734

Query: 80  CVATLLMAGAD 90
             A L  AGAD
Sbjct: 735 LAALLKAAGAD 745


>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
          Length = 1001

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 52/150 (34%), Positives = 72/150 (48%), Gaps = 14/150 (9%)

Query: 10  SVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 69
           SV+ L  H  FLDV   D  G T LM+A+  GH  + S LL    G  +   D+   +AL
Sbjct: 135 SVLLLCDHEAFLDVLDND--GRTPLMIASLGGHAAICSQLLQR--GARVNVTDKNDKSAL 190

Query: 70  MKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWR-IRQLL--RRPQ 126
           + A  +   E    LL  GAD  AVD   G  AL +A+ T     +WR ++Q L  RR  
Sbjct: 191 ILACEKGSAEVAELLLSHGADAGAVDST-GHDALHYALHTQD-KALWRHLQQALSRRRRG 248

Query: 127 VEQLSQHYKPEWPALSGLVAQAQAQAQVAP 156
            ++L QH     P L+   + ++ QA   P
Sbjct: 249 GQRLVQH-----PDLASQASPSEPQAGSPP 273



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 3/104 (2%)

Query: 3   ACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRD 62
           A + G    VA L+        + D  G +   LAA  G    +++LL    G D+  ++
Sbjct: 27  AVHRGDVGRVAALASRKSARPTKLDSNGQSPFHLAASKGLTECLTILLAN--GADINSKN 84

Query: 63  QRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWA 106
           + G TAL  A +  + +CV  LL  GA+  AVD    ++ L WA
Sbjct: 85  EDGSTALHLATISCQPQCVKVLLQHGANEDAVD-AENRSPLHWA 127


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
           polymerase [Homo sapiens]
          Length = 1327

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 5/110 (4%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           + A Y+  +    LL H    DVN QDKGG   L  AA  GHV + +LL+ Y     +  
Sbjct: 843 LAAGYNNLEVAEYLLEHGA--DVNAQDKGGLIPLHNAASYGHVDIAALLIKY--NTCVNA 898

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTD 110
            D+   T L +AA + R +  A LL  GAD T  +   G+T L+ A   D
Sbjct: 899 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQ-EGQTPLDLATADD 947



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 5/106 (4%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           + A Y+  + V  LL H    DV+ +DKGG   L  A   GH  +  LLL +  G  +  
Sbjct: 375 LAAGYNRVRIVQLLLQHGA--DVHAKDKGGLVPLHNACSYGHYEVTELLLKH--GACVNA 430

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWA 106
            D    T L +AA +NR E  + LL  GAD T V+   GK+A++ A
Sbjct: 431 MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVN-CHGKSAVDMA 475



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 3/85 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           +V+ +D GG   L  A   GH  +VSLLL    G D   RD    T L +AA++ + +  
Sbjct: 241 NVHARDDGGLIPLHNACSFGHAEVVSLLLCQ--GADPNARDNWNYTPLHEAAIKGKIDVC 298

Query: 82  ATLLMAGADLTAVDPVRGKTALEWA 106
             LL  GAD   +    GK+AL+ A
Sbjct: 299 IVLLQHGAD-PNIRNTDGKSALDLA 322



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 10  SVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 69
           SVV  L H    DV+ +DKGG   L  A   GH  +  LL+ +  G  +   D    T L
Sbjct: 698 SVVEYLLHHG-ADVHAKDKGGLVPLHNACSYGHYEVAELLVRH--GASVNVADLWKFTPL 754

Query: 70  MKAAMRNRCECVATLLMAGADLT 92
            +AA + + E    LL  GAD T
Sbjct: 755 HEAAAKGKYEICKLLLKHGADPT 777



 Score = 35.4 bits (80), Expect = 0.053
 Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 7/89 (7%)

Query: 9   QSVVALLSHCPFLDVNQQDKGG--DTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGL 66
           + ++ALL+    L+VN     G   T L LAA    V +V LLL +  G D+  +D+ GL
Sbjct: 349 EKLMALLTP---LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH--GADVHAKDKGGL 403

Query: 67  TALMKAAMRNRCECVATLLMAGADLTAVD 95
             L  A      E    LL  GA + A+D
Sbjct: 404 VPLHNACSYGHYEVTELLLKHGACVNAMD 432



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 6/95 (6%)

Query: 3   ACYHGFQSVVALLSHCPFLDVNQQDKGG--DTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           AC +G  S V  L      +VN +D  G   + L  AA  G   +V  LL   +G ++  
Sbjct: 189 ACRNGDVSRVKRLVDAA--NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQ--MGANVHA 244

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVD 95
           RD  GL  L  A      E V+ LL  GAD  A D
Sbjct: 245 RDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARD 279



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 3/83 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           +VN+++K   T L +AA+  H  ++ +L  +  G  +   D  G TAL +AA+    +  
Sbjct: 550 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKH--GAKMNALDTLGQTALHRAALAGHLQTC 607

Query: 82  ATLLMAGADLTAVDPVRGKTALE 104
             LL  G+D + +  ++G TA +
Sbjct: 608 RLLLSYGSDPSIIS-LQGFTAAQ 629


>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
           sapiens]
          Length = 1771

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 44/111 (39%), Positives = 59/111 (53%), Gaps = 12/111 (10%)

Query: 1   MVACYHGF-QSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLE 59
           +VA   G+ QSV  +L   P  +VN  DK G+TALM+A++ GH  +V  LL+   G  + 
Sbjct: 208 IVAVKGGYTQSVKEILKRNP--NVNLTDKDGNTALMIASKEGHTEIVQDLLD--AGTYVN 263

Query: 60  RRDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRG---KTALEWAV 107
             D+ G T L+ A      E V  LL   AD+     +RG   KTAL WAV
Sbjct: 264 IPDRSGDTVLIGAVRGGHVEIVRALLQKYADI----DIRGQDNKTALYWAV 310



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 5/131 (3%)

Query: 13  ALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKA 72
           ALL  C   DV+++++ G T LM+AA+ G++ +V  L+      +LE  D    TAL+ A
Sbjct: 23  ALLEKCK--DVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLE--DLDNWTALISA 78

Query: 73  AMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQ 132
           +       V  LL  G +L   D + G TAL WA      D V  +      P V  L  
Sbjct: 79  SKEGHVHIVEELLKCGVNLEHRD-MGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYS 137

Query: 133 HYKPEWPALSG 143
            Y   W A  G
Sbjct: 138 VYPIIWAAGRG 148



 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 35/116 (30%), Positives = 48/116 (41%), Gaps = 32/116 (27%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQR------------------ 64
           VN  D+ GDT L+ A + GHV +V  LL  Y  +D+  +D +                  
Sbjct: 262 VNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDI 321

Query: 65  -------------GLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAV 107
                        G T L+KA      E V  LL  GA ++AVD  +G T L  A+
Sbjct: 322 LQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDK-KGDTPLHIAI 376



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 47/130 (36%), Positives = 58/130 (44%), Gaps = 12/130 (9%)

Query: 1   MVACYHGFQSVVALL-SHCPFLDVNQQDKGGDTA--LMLAAQAGHVPLVSLLLNYYVGLD 57
           M ACY G   VV LL SH      N    G  +   ++ AA  GH  +V LLL    G  
Sbjct: 109 MWACYKGRTDVVELLLSH----GANPSVTGLYSVYPIIWAAGRGHADIVHLLLQN--GAK 162

Query: 58  LERRDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWR 117
           +   D+ G T L+ AA +   ECV  LL  GAD+   +     TAL  AV      +V  
Sbjct: 163 VNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQ-EGANSMTALIVAVKGGYTQSVKE 221

Query: 118 IRQLLRRPQV 127
           I  L R P V
Sbjct: 222 I--LKRNPNV 229



 Score = 36.2 bits (82), Expect = 0.031
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           DV+Q+     TAL++A + G+   V  +L     ++L  +D  G TALM A+     E V
Sbjct: 195 DVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKD--GNTALMIASKEGHTEIV 252

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAV 107
             LL AG  +   D   G T L  AV
Sbjct: 253 QDLLDAGTYVNIPDR-SGDTVLIGAV 277


>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
          Length = 860

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 61/201 (30%), Positives = 87/201 (43%), Gaps = 20/201 (9%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           +++Q+D  G T +MLAA  G   L+ LL+    G  +  R + G TAL+ AA +N    V
Sbjct: 593 NLDQEDSSGMTLVMLAAAGGQDDLLRLLITK--GAKVNGRQKNGTTALIHAAEKNFLTTV 650

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPAL 141
           A LL AGA    V    G+TAL  A    + D V  + +         LS+H        
Sbjct: 651 AILLEAGA-FVNVQQSNGETALMKACKRGNSDIVRLVIEC--GADCNILSKHQN------ 701

Query: 142 SGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHT 201
           S L    Q+   +   LL+    TLS        E  + D+   A  +L  P    ACH 
Sbjct: 702 SALHFAKQSNNVLVYDLLKNHLETLS-----RVAEETIKDYF-EARLALLEPVFPIACHR 755

Query: 202 LC--PDHPPSLGTR-SKSVPE 219
           LC  PD       +  +++PE
Sbjct: 756 LCEGPDFSTDFNYKPPQNIPE 776


>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
          Length = 821

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 47/126 (37%), Positives = 64/126 (50%), Gaps = 12/126 (9%)

Query: 6   HGFQSVVALLSHCPFLDVNQQDKGGDTALMLAA------QAGHVPLVSLLLNYYVGLDLE 59
           HG  ++ +LL      +VN+Q++ G +ALMLAA      +   + +V  L  + +G    
Sbjct: 633 HGNLAIASLLLDTGACEVNRQNRAGYSALMLAALTSVRQEEEDMAVVQRL--FCMGDVNA 690

Query: 60  RRDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIR 119
           +  Q G TALM A    R + VATLL  GAD+ A D   G TAL  A      DTV   R
Sbjct: 691 KASQTGQTALMLAISHGRQDMVATLLACGADVNAQD-ADGATALMCASEYGRLDTV---R 746

Query: 120 QLLRRP 125
            LL +P
Sbjct: 747 LLLTQP 752



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 22  DVNQQ-DKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           DVN +  + G TALMLA   G   +V+ LL    G D+  +D  G TALM A+   R + 
Sbjct: 687 DVNAKASQTGQTALMLAISHGRQDMVATLLA--CGADVNAQDADGATALMCASEYGRLDT 744

Query: 81  VATLL-MAGADLTAVDPVRGKTALEWAV 107
           V  LL   G D   +D   G +AL  A+
Sbjct: 745 VRLLLTQPGCDPAILDN-EGTSALAIAL 771


>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 37/97 (38%), Positives = 52/97 (53%), Gaps = 3/97 (3%)

Query: 24  NQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVAT 83
           N +D  G+TAL  A    ++ +   LL Y  G D+E R Q G T+L+ A  R + + VA 
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAY--GADIEARSQDGHTSLLLAVNRKKEQMVAF 189

Query: 84  LLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           LL    DLTA+D   G+TAL  A    S   V+++ Q
Sbjct: 190 LLKKKPDLTAIDNF-GRTALILAARNGSTSVVYQLLQ 225



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           D+N +DK   TAL+LA   G   +V+ L+     L+L   D    TAL+KA       C 
Sbjct: 64  DLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNL--TDSENRTALIKAVQCQEEVCA 121

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAV 107
           + LL  GA+    D + G TAL +A+
Sbjct: 122 SILLEHGANPNVRD-MYGNTALHYAI 146


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 32/89 (35%), Positives = 49/89 (55%), Gaps = 3/89 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N +D  G+  L+LA Q GH  +   LL++  G D+  R++ G TALM A        V 
Sbjct: 148 INLKDLDGNIPLLLAVQNGHSEICHFLLDH--GADVNSRNKSGRTALMLACEIGSSNAVE 205

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDS 111
            L+  GADL  VD + G  AL ++ L+++
Sbjct: 206 ALIKKGADLNLVDSL-GYNALHYSKLSEN 233



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)

Query: 25  QQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATL 84
           + D  G TA  LAA  GHV  + +++ +  G+D+  +D  G +AL  AA  +  EC+  L
Sbjct: 51  KHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVTAQDTTGHSALHLAAKNSHHECIRKL 108

Query: 85  LMAGADLTAVDPVRGKTALEWA 106
           L +     +VD   GKTAL +A
Sbjct: 109 LQSKCPAESVDS-SGKTALHYA 129



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 31  DTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATLLMAGAD 90
           D  L+ A + G    V+ LL    G    + D  G TA   AA +   EC+  ++  G D
Sbjct: 23  DDRLLQAVENGDAEKVASLLGKK-GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVD 81

Query: 91  LTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           +TA D   G +AL  A      + + ++ Q
Sbjct: 82  VTAQD-TTGHSALHLAAKNSHHECIRKLLQ 110



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 18  CPFL-----DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 69
           C FL     DVN ++K G TALMLA + G    V  L+    G DL   D  G  AL
Sbjct: 171 CHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 225



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 21  LDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           +DV  QD  G +AL LAA+  H   +  LL        E  D  G TAL  AA +   + 
Sbjct: 80  VDVTAQDTTGHSALHLAAKNSHHECIRKLLQ--SKCPAESVDSSGKTALHYAAAQGCLQA 137

Query: 81  VATL 84
           V  L
Sbjct: 138 VQIL 141


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 32/89 (35%), Positives = 49/89 (55%), Gaps = 3/89 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N +D  G+  L+LA Q GH  +   LL++  G D+  R++ G TALM A        V 
Sbjct: 137 INLKDLDGNIPLLLAVQNGHSEICHFLLDH--GADVNSRNKSGRTALMLACEIGSSNAVE 194

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDS 111
            L+  GADL  VD + G  AL ++ L+++
Sbjct: 195 ALIKKGADLNLVDSL-GYNALHYSKLSEN 222



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)

Query: 25  QQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATL 84
           + D  G TA  LAA  GHV  + +++ +  G+D+  +D  G +AL  AA  +  EC+  L
Sbjct: 40  KHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVTAQDTTGHSALHLAAKNSHHECIRKL 97

Query: 85  LMAGADLTAVDPVRGKTALEWA 106
           L +     +VD   GKTAL +A
Sbjct: 98  LQSKCPAESVDS-SGKTALHYA 118



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 31  DTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATLLMAGAD 90
           D  L+ A + G    V+ LL    G    + D  G TA   AA +   EC+  ++  G D
Sbjct: 12  DDRLLQAVENGDAEKVASLLGKK-GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVD 70

Query: 91  LTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           +TA D   G +AL  A      + + ++ Q
Sbjct: 71  VTAQD-TTGHSALHLAAKNSHHECIRKLLQ 99



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 18  CPFL-----DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 69
           C FL     DVN ++K G TALMLA + G    V  L+    G DL   D  G  AL
Sbjct: 160 CHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 214



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 21  LDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           +DV  QD  G +AL LAA+  H   +  LL        E  D  G TAL  AA +   + 
Sbjct: 69  VDVTAQDTTGHSALHLAAKNSHHECIRKLLQ--SKCPAESVDSSGKTALHYAAAQGCLQA 126

Query: 81  VATL 84
           V  L
Sbjct: 127 VQIL 130


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 32/89 (35%), Positives = 49/89 (55%), Gaps = 3/89 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N +D  G+  L+LA Q GH  +   LL++  G D+  R++ G TALM A        V 
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDH--GADVNSRNKSGRTALMLACEIGSSNAVE 202

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDS 111
            L+  GADL  VD + G  AL ++ L+++
Sbjct: 203 ALIKKGADLNLVDSL-GYNALHYSKLSEN 230



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)

Query: 25  QQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATL 84
           + D  G TA  LAA  GHV  + +++ +  G+D+  +D  G +AL  AA  +  EC+  L
Sbjct: 48  KHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVTAQDTTGHSALHLAAKNSHHECIRKL 105

Query: 85  LMAGADLTAVDPVRGKTALEWA 106
           L +     +VD   GKTAL +A
Sbjct: 106 LQSKCPAESVDS-SGKTALHYA 126



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           D N+ +K  D  L+ A + G    V+ LL    G    + D  G TA   AA +   EC+
Sbjct: 12  DTNEWNKNDDR-LLQAVENGDAEKVASLLGKK-GASATKHDSEGKTAFHLAAAKGHVECL 69

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
             ++  G D+TA D   G +AL  A      + + ++ Q
Sbjct: 70  RVMITHGVDVTAQD-TTGHSALHLAAKNSHHECIRKLLQ 107



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 18  CPFL-----DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 69
           C FL     DVN ++K G TALMLA + G    V  L+    G DL   D  G  AL
Sbjct: 168 CHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 222



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 21  LDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           +DV  QD  G +AL LAA+  H   +  LL        E  D  G TAL  AA +   + 
Sbjct: 77  VDVTAQDTTGHSALHLAAKNSHHECIRKLLQ--SKCPAESVDSSGKTALHYAAAQGCLQA 134

Query: 81  VATL 84
           V  L
Sbjct: 135 VQIL 138


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 32/89 (35%), Positives = 49/89 (55%), Gaps = 3/89 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N +D  G+  L+LA Q GH  +   LL++  G D+  R++ G TALM A        V 
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDH--GADVNSRNKSGRTALMLACEIGSSNAVE 202

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDS 111
            L+  GADL  VD + G  AL ++ L+++
Sbjct: 203 ALIKKGADLNLVDSL-GYNALHYSKLSEN 230



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)

Query: 25  QQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATL 84
           + D  G TA  LAA  GHV  + +++ +  G+D+  +D  G +AL  AA  +  EC+  L
Sbjct: 48  KHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVTAQDTTGHSALHLAAKNSHHECIRKL 105

Query: 85  LMAGADLTAVDPVRGKTALEWA 106
           L +     +VD   GKTAL +A
Sbjct: 106 LQSKCPAESVDS-SGKTALHYA 126



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           D N+ +K  D  L+ A + G    V+ LL    G    + D  G TA   AA +   EC+
Sbjct: 12  DTNEWNKNDDR-LLQAVENGDAEKVASLLGKK-GASATKHDSEGKTAFHLAAAKGHVECL 69

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
             ++  G D+TA D   G +AL  A      + + ++ Q
Sbjct: 70  RVMITHGVDVTAQD-TTGHSALHLAAKNSHHECIRKLLQ 107



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 18  CPFL-----DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 69
           C FL     DVN ++K G TALMLA + G    V  L+    G DL   D  G  AL
Sbjct: 168 CHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 222



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 21  LDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           +DV  QD  G +AL LAA+  H   +  LL        E  D  G TAL  AA +   + 
Sbjct: 77  VDVTAQDTTGHSALHLAAKNSHHECIRKLLQ--SKCPAESVDSSGKTALHYAAAQGCLQA 134

Query: 81  VATL 84
           V  L
Sbjct: 135 VQIL 138


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 32/89 (35%), Positives = 49/89 (55%), Gaps = 3/89 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N +D  G+  L+LA Q GH  +   LL++  G D+  R++ G TALM A        V 
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDH--GADVNSRNKSGRTALMLACEIGSSNAVE 202

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDS 111
            L+  GADL  VD + G  AL ++ L+++
Sbjct: 203 ALIKKGADLNLVDSL-GYNALHYSKLSEN 230



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)

Query: 25  QQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATL 84
           + D  G TA  LAA  GHV  + +++ +  G+D+  +D  G +AL  AA  +  EC+  L
Sbjct: 48  KHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVTAQDTTGHSALHLAAKNSHHECIRKL 105

Query: 85  LMAGADLTAVDPVRGKTALEWA 106
           L +     +VD   GKTAL +A
Sbjct: 106 LQSKCPAESVDS-SGKTALHYA 126



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           D N+ +K  D  L+ A + G    V+ LL    G    + D  G TA   AA +   EC+
Sbjct: 12  DTNEWNKNDDR-LLQAVENGDAEKVASLLGKK-GASATKHDSEGKTAFHLAAAKGHVECL 69

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
             ++  G D+TA D   G +AL  A      + + ++ Q
Sbjct: 70  RVMITHGVDVTAQD-TTGHSALHLAAKNSHHECIRKLLQ 107



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 18  CPFL-----DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 69
           C FL     DVN ++K G TALMLA + G    V  L+    G DL   D  G  AL
Sbjct: 168 CHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 222



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 21  LDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           +DV  QD  G +AL LAA+  H   +  LL        E  D  G TAL  AA +   + 
Sbjct: 77  VDVTAQDTTGHSALHLAAKNSHHECIRKLLQ--SKCPAESVDSSGKTALHYAAAQGCLQA 134

Query: 81  VATL 84
           V  L
Sbjct: 135 VQIL 138


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 32/89 (35%), Positives = 49/89 (55%), Gaps = 3/89 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N +D  G+  L+LA Q GH  +   LL++  G D+  R++ G TALM A        V 
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDH--GADVNSRNKSGRTALMLACEIGSSNAVE 202

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDS 111
            L+  GADL  VD + G  AL ++ L+++
Sbjct: 203 ALIKKGADLNLVDSL-GYNALHYSKLSEN 230



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)

Query: 25  QQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATL 84
           + D  G TA  LAA  GHV  + +++ +  G+D+  +D  G +AL  AA  +  EC+  L
Sbjct: 48  KHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVTAQDTTGHSALHLAAKNSHHECIRKL 105

Query: 85  LMAGADLTAVDPVRGKTALEWA 106
           L +     +VD   GKTAL +A
Sbjct: 106 LQSKCPAESVDS-SGKTALHYA 126



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           D N+ +K  D  L+ A + G    V+ LL    G    + D  G TA   AA +   EC+
Sbjct: 12  DTNEWNKNDDR-LLQAVENGDAEKVASLLGKK-GASATKHDSEGKTAFHLAAAKGHVECL 69

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
             ++  G D+TA D   G +AL  A      + + ++ Q
Sbjct: 70  RVMITHGVDVTAQD-TTGHSALHLAAKNSHHECIRKLLQ 107



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 18  CPFL-----DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 69
           C FL     DVN ++K G TALMLA + G    V  L+    G DL   D  G  AL
Sbjct: 168 CHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 222



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 21  LDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           +DV  QD  G +AL LAA+  H   +  LL        E  D  G TAL  AA +   + 
Sbjct: 77  VDVTAQDTTGHSALHLAAKNSHHECIRKLLQ--SKCPAESVDSSGKTALHYAAAQGCLQA 134

Query: 81  VATL 84
           V  L
Sbjct: 135 VQIL 138


>gi|39812133 ankyrin repeat domain 2 isoform a [Homo sapiens]
          Length = 360

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 53/152 (34%), Positives = 72/152 (47%), Gaps = 13/152 (8%)

Query: 3   ACYHGFQSVVALL-SHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
           AC  G   VV LL SH    D N +DK   T L +A + G V +V   L+  +GL++  R
Sbjct: 221 ACRGGHLEVVKLLQSHGA--DTNVRDKLLSTPLHVAVRTGQVEIVEHFLS--LGLEINAR 276

Query: 62  DQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQL 121
           D+ G TAL  A   NR + +  LL+ GAD+   + + GKT  +   L  + DT    R  
Sbjct: 277 DREGDTALHDAVRLNRYKIIKLLLLHGADMMTKN-LAGKTPTDLVQLWQA-DT----RHA 330

Query: 122 LRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQ 153
           L  P  E  ++H   E P  SG        AQ
Sbjct: 331 LEHP--EPGAEHNGLEGPNDSGRETPQPVPAQ 360


>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
          Length = 917

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 36/97 (37%), Positives = 52/97 (53%), Gaps = 3/97 (3%)

Query: 24  NQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVAT 83
           N +D  G+TAL  A    ++ +   LL Y  G D+E R Q G T+L+ A  R + + V+ 
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAY--GADIEARSQDGHTSLLLAVNRKKEQMVSF 189

Query: 84  LLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           LL    DLTA+D   G+TAL  A    S   V+++ Q
Sbjct: 190 LLKKKPDLTAIDNF-GRTALILAARNGSTSVVYQLLQ 225



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           D+N +DK   TAL+LA   G   +V+ L+     L+L   D    TAL+KA       C 
Sbjct: 64  DLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNL--TDSENRTALIKAVQCQEEVCA 121

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAV 107
           + LL  GA+    D + G TAL +A+
Sbjct: 122 SILLEHGANPNVRD-MYGNTALHYAI 146


>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
           sapiens]
          Length = 917

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 36/97 (37%), Positives = 52/97 (53%), Gaps = 3/97 (3%)

Query: 24  NQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVAT 83
           N +D  G+TAL  A    ++ +   LL Y  G D+E R Q G T+L+ A  R + + V+ 
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAY--GADIEARSQDGHTSLLLAVNRKKEQMVSF 189

Query: 84  LLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
           LL    DLTA+D   G+TAL  A    S   V+++ Q
Sbjct: 190 LLKKKPDLTAIDNF-GRTALILAARNGSTSVVYQLLQ 225



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           D+N +DK   TAL+LA   G   +V+ L+     L+L   D    TAL+KA       C 
Sbjct: 64  DLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNL--TDSENRTALIKAVQCQEEVCA 121

Query: 82  ATLLMAGADLTAVDPVRGKTALEWAV 107
           + LL  GA+    D + G TAL +A+
Sbjct: 122 SILLEHGANPNVRD-MYGNTALHYAI 146


>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
            1 [Homo sapiens]
          Length = 1298

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 59/205 (28%), Positives = 85/205 (41%), Gaps = 12/205 (5%)

Query: 2    VACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
            +A   G   VV  L     +DVN QD GG T ++ A +  HV LV LLL+   G D+  R
Sbjct: 845  LAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS--KGSDINIR 902

Query: 62   DQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQL 121
            D      L  AA     +    LL A  DL AV+ + G + L  A   + +D V  +  L
Sbjct: 903  DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVN-IHGDSPLHIAARENRYDCV--VLFL 959

Query: 122  LRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVLD 181
             R   V   ++  +      S L +Q  +  Q++ +L +      S P  PSP E  V  
Sbjct: 960  SRDSDVTLKNKEGETPLQCAS-LNSQVWSALQMSKALQD------SAPDRPSPVERIVSR 1012

Query: 182  HLVTATTSLASPFVTTACHTLCPDH 206
             +      +  P V       CP +
Sbjct: 1013 DIARGYERIPIPCVNAVDSEPCPSN 1037



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 7/84 (8%)

Query: 34  LMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVATLLMAGADLTA 93
           L  AA+AGHV +  +L+     +D    DQR  T LM+AA  N  E V  L+ AGA    
Sbjct: 777 LHAAAEAGHVDICHMLVQAGANIDTCSEDQR--TPLMEAAENNHLEAVKYLIKAGA---L 831

Query: 94  VDP--VRGKTALEWAVLTDSFDTV 115
           VDP    G T L  A     ++ V
Sbjct: 832 VDPKDAEGSTCLHLAAKKGHYEVV 855



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           V+ +D  G T L LAA+ GH  +V  LL+    +D+  +D  G T ++ A      + V 
Sbjct: 832 VDPKDAEGSTCLHLAAKKGHYEVVQYLLS-NGQMDVNCQDDGGWTPMIWATEYKHVDLVK 890

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDSFD 113
            LL  G+D+   D       L WA  +   D
Sbjct: 891 LLLSKGSDINIRDN-EENICLHWAAFSGCVD 920


>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
           polymerase 2 [Homo sapiens]
          Length = 1166

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 38/104 (36%), Positives = 52/104 (50%), Gaps = 5/104 (4%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           + A Y+  +    LL H    DVN QDKGG   L  AA  GHV + +LL+ Y     +  
Sbjct: 685 LAAGYNNLEVAEYLLQHGA--DVNAQDKGGLIPLHNAASYGHVDVAALLIKY--NACVNA 740

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALE 104
            D+   T L +AA + R +  A LL  GAD T  +   G+T L+
Sbjct: 741 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQ-EGQTPLD 783



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 22  DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECV 81
           +V  +D GG   L  A   GH  +V+LLL +  G D   RD    T L +AA++ + +  
Sbjct: 83  NVQARDDGGLIPLHNACSFGHAEVVNLLLRH--GADPNARDNWNYTPLHEAAIKGKIDVC 140

Query: 82  ATLLMAGADLTAVDPVRGKTALEWA 106
             LL  GA+ T +    G+TAL+ A
Sbjct: 141 IVLLQHGAEPT-IRNTDGRTALDLA 164



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 35/106 (33%), Positives = 52/106 (49%), Gaps = 5/106 (4%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           + A Y+  + V  LL H    DV+ +DKG    L  A   GH  +  LL+ +  G  +  
Sbjct: 217 LAAGYNRVKIVQLLLQHGA--DVHAKDKGDLVPLHNACSYGHYEVTELLVKH--GACVNA 272

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWA 106
            D    T L +AA +NR E  + LL  GAD T ++    K+A++ A
Sbjct: 273 MDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLN-CHNKSAIDLA 317



 Score = 36.6 bits (83), Expect = 0.024
 Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 3   ACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRD 62
           A Y+    V  LL H    DV+ +DKGG   L  A   GH  +  LL+ +  G  +   D
Sbjct: 534 AGYNRVSVVEYLLQHGA--DVHAKDKGGLVPLHNACSYGHYEVAELLVKH--GAVVNVAD 589

Query: 63  QRGLTALMKAAMRNRCECVATLLMAGADLT 92
               T L +AA + + E    LL  GAD T
Sbjct: 590 LWKFTPLHEAAAKGKYEICKLLLQHGADPT 619



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 28/75 (37%), Positives = 33/75 (44%), Gaps = 4/75 (5%)

Query: 23  VNQQDKGG--DTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCEC 80
           VN +D  G   T L  AA  G   +V  LL    G +++ RD  GL  L  A      E 
Sbjct: 49  VNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQN--GANVQARDDGGLIPLHNACSFGHAEV 106

Query: 81  VATLLMAGADLTAVD 95
           V  LL  GAD  A D
Sbjct: 107 VNLLLRHGADPNARD 121



 Score = 32.0 bits (71), Expect = 0.59
 Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 7/89 (7%)

Query: 9   QSVVALLSHCPFLDVNQQDKGG--DTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGL 66
           + ++ALL+    L+VN     G   T L LAA    V +V LLL +  G D+  +D+  L
Sbjct: 191 EKMMALLTP---LNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH--GADVHAKDKGDL 245

Query: 67  TALMKAAMRNRCECVATLLMAGADLTAVD 95
             L  A      E    L+  GA + A+D
Sbjct: 246 VPLHNACSYGHYEVTELLVKHGACVNAMD 274



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 28/69 (40%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           VN  D  G T+L  AA  GH+    LLL+Y  G D      +G TAL    M N  E V 
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSY--GCDPNIISLQGFTALQ---MGN--ENVQ 478

Query: 83  TLLMAGADL 91
            LL  G  L
Sbjct: 479 QLLQEGISL 487


>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 2 [Homo sapiens]
          Length = 1990

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 39/108 (36%), Positives = 52/108 (48%), Gaps = 5/108 (4%)

Query: 8    FQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLT 67
            +Q V  LL+H    DVN  DK G T LM+AA  GH+  V  LL    G  +   D+ GLT
Sbjct: 1080 WQIVDLLLTHGA--DVNMADKQGRTPLMMAASEGHLGTVDFLLAQ--GASIALMDKEGLT 1135

Query: 68   ALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTV 115
            AL  A ++     V +L+  GA     D   G+T L+ A      + V
Sbjct: 1136 ALSWACLKGHLSVVRSLVDNGAATDHADK-NGRTPLDLAAFYGDAEVV 1182



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 12/124 (9%)

Query: 1    MVACYHGFQSVVALLSHCPFLDVNQQDKG---------GDTALMLAAQAGHVPLVSLLLN 51
            + A   G+  +V+ L   P  D  + ++          G+TAL  AA  G + +  LLL 
Sbjct: 996  IAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLE 1055

Query: 52   YYVGLDLERRDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDS 111
               G  + + ++RG   L     +   + V  LL  GAD+   D  +G+T L  A     
Sbjct: 1056 Q--GAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADK-QGRTPLMMAASEGH 1112

Query: 112  FDTV 115
              TV
Sbjct: 1113 LGTV 1116



 Score = 34.7 bits (78), Expect = 0.091
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 5/90 (5%)

Query: 3    ACYHGFQSVV-ALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
            AC  G  SVV +L+ +    D    DK G T L LAA  G   +V  L+++  G  +E  
Sbjct: 1140 ACLKGHLSVVRSLVDNGAATD--HADKNGRTPLDLAAFYGDAEVVQFLVDH--GAMIEHV 1195

Query: 62   DQRGLTALMKAAMRNRCECVATLLMAGADL 91
            D  G+  L +A        V TLL  GA +
Sbjct: 1196 DYSGMRPLDRAVGCRNTSVVVTLLKKGAKI 1225



 Score = 30.0 bits (66), Expect = 2.2
 Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 15/115 (13%)

Query: 7    GFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGL-----DLERR 61
            G+ S+V LL       V+  DK G  AL+ AA  GH+ +V  L+     +      + ++
Sbjct: 929  GYLSIVVLLCK-KRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKK 987

Query: 62   DQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVW 116
                  AL+ AA     E V+ LL    DL    P + +  +E A + +SFD++W
Sbjct: 988  SHAIQQALIAAASMGYTEIVSYLL----DL----PEKDEEEVERAQI-NSFDSLW 1033


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           +N +DK   TAL LA   GH  +V+LL++    L++   D    TALMKA      +C  
Sbjct: 73  LNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNV--CDNENRTALMKAVQCQEEKCAT 130

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRI 118
            LL  GAD    D V G TAL +AV  +      ++
Sbjct: 131 ILLEHGADPNLAD-VHGNTALHYAVYNEDISVATKL 165


>gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3
           [Homo sapiens]
          Length = 627

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 40/106 (37%), Positives = 50/106 (47%), Gaps = 3/106 (2%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           M AC  G   V  LL       VN      ++ L LAA  GHV L +LL+    G +LE 
Sbjct: 410 MEACMDGHVEVARLLLDSG-AQVNMPADSFESPLTLAACGGHVELAALLIER--GANLEE 466

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWA 106
            +  G T LM+AA     E VA LL  GA++ A      +TAL  A
Sbjct: 467 VNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLA 512



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 39/115 (33%), Positives = 52/115 (45%), Gaps = 3/115 (2%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           M A   G+  +V LL      DVN Q   G+TAL  A   G V +V +LLN   G ++E 
Sbjct: 277 MAASSGGYLDIVKLLL-LHDADVNSQSATGNTALTYACAGGFVDIVKVLLN--EGANIED 333

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTV 115
            ++ G T LM+AA     E    LL  GA +        ++AL  A      D V
Sbjct: 334 HNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMV 388



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           VN+  + G++ L LA  AG+  L  +LL  +  ++ +R ++  +T LM A+     + V 
Sbjct: 231 VNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE-DRGNKGDITPLMAASSGGYLDIVK 289

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDSFDTV 115
            LL+  AD+ +     G TAL +A      D V
Sbjct: 290 LLLLHDADVNS-QSATGNTALTYACAGGFVDIV 321



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 8/103 (7%)

Query: 2   VACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
           +AC  GF  V   L      D+   + G  T LM A+Q GH+ LV  LL    G ++   
Sbjct: 511 LACCGGFSEVADFLIKAG-ADI---ELGCSTPLMEASQEGHLELVKYLLAS--GANVHAT 564

Query: 62  DQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALE 104
              G TAL  A      +    LL AGADL   + +  KT LE
Sbjct: 565 TATGDTALTYACENGHTDVADVLLQAGADLDKQEDM--KTILE 605



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 33/121 (27%)

Query: 3   ACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGL------ 56
           AC  GF  +V +L +    ++   ++ G T LM AA AGHV +  +LL++  G+      
Sbjct: 312 ACAGGFVDIVKVLLN-EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNE 370

Query: 57  --------------------------DLERRDQRGLTALMKAAMRNRCECVATLLMAGAD 90
                                     D E +     TALM+A M    E    LL +GA 
Sbjct: 371 FKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQ 430

Query: 91  L 91
           +
Sbjct: 431 V 431


>gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2
           [Homo sapiens]
          Length = 616

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 40/106 (37%), Positives = 50/106 (47%), Gaps = 3/106 (2%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           M AC  G   V  LL       VN      ++ L LAA  GHV L +LL+    G +LE 
Sbjct: 399 MEACMDGHVEVARLLLDSG-AQVNMPADSFESPLTLAACGGHVELAALLIER--GANLEE 455

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWA 106
            +  G T LM+AA     E VA LL  GA++ A      +TAL  A
Sbjct: 456 VNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLA 501



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 39/115 (33%), Positives = 52/115 (45%), Gaps = 3/115 (2%)

Query: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
           M A   G+  +V LL      DVN Q   G+TAL  A   G V +V +LLN   G ++E 
Sbjct: 266 MAASSGGYLDIVKLLL-LHDADVNSQSATGNTALTYACAGGFVDIVKVLLN--EGANIED 322

Query: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTV 115
            ++ G T LM+AA     E    LL  GA +        ++AL  A      D V
Sbjct: 323 HNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMV 377



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)

Query: 23  VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCECVA 82
           VN+  + G++ L LA  AG+  L  +LL  +  ++ +R ++  +T LM A+     + V 
Sbjct: 220 VNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE-DRGNKGDITPLMAASSGGYLDIVK 278

Query: 83  TLLMAGADLTAVDPVRGKTALEWAVLTDSFDTV 115
            LL+  AD+ +     G TAL +A      D V
Sbjct: 279 LLLLHDADVNS-QSATGNTALTYACAGGFVDIV 310



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 8/103 (7%)

Query: 2   VACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERR 61
           +AC  GF  V   L      D+   + G  T LM A+Q GH+ LV  LL    G ++   
Sbjct: 500 LACCGGFSEVADFLIKAG-ADI---ELGCSTPLMEASQEGHLELVKYLLAS--GANVHAT 553

Query: 62  DQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALE 104
              G TAL  A      +    LL AGADL   + +  KT LE
Sbjct: 554 TATGDTALTYACENGHTDVADVLLQAGADLDKQEDM--KTILE 594



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 33/121 (27%)

Query: 3   ACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGL------ 56
           AC  GF  +V +L +    ++   ++ G T LM AA AGHV +  +LL++  G+      
Sbjct: 301 ACAGGFVDIVKVLLN-EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNE 359

Query: 57  --------------------------DLERRDQRGLTALMKAAMRNRCECVATLLMAGAD 90
                                     D E +     TALM+A M    E    LL +GA 
Sbjct: 360 FKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQ 419

Query: 91  L 91
           +
Sbjct: 420 V 420


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,825,439
Number of Sequences: 37866
Number of extensions: 500150
Number of successful extensions: 3751
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 178
Number of HSP's successfully gapped in prelim test: 154
Number of HSP's that attempted gapping in prelim test: 2463
Number of HSP's gapped (non-prelim): 1071
length of query: 272
length of database: 18,247,518
effective HSP length: 101
effective length of query: 171
effective length of database: 14,423,052
effective search space: 2466341892
effective search space used: 2466341892
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.