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Search of human proteins with 190886435
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190886435 RALBP1 associated Eps domain containing 1 isoform
a [Homo sapiens]
(795 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190886435 RALBP1 associated Eps domain containing 1 isoform a... 1597 0.0
gi|190886437 RALBP1 associated Eps domain containing 1 isoform b... 1524 0.0
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 350 3e-96
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 345 7e-95
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 72 2e-12
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 72 2e-12
gi|7657056 EH-domain containing 3 [Homo sapiens] 71 3e-12
gi|30240932 EH-domain containing 1 [Homo sapiens] 71 3e-12
gi|4503593 epidermal growth factor receptor pathway substrate 15... 71 4e-12
gi|10864047 epidermal growth factor receptor pathway substrate 1... 70 1e-11
gi|21361462 EH-domain containing 2 [Homo sapiens] 69 2e-11
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 68 3e-11
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 68 3e-11
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 68 3e-11
gi|21264315 EH-domain containing 4 [Homo sapiens] 67 6e-11
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 54 6e-07
gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho... 50 8e-06
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens] 50 8e-06
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens] 50 8e-06
gi|15529996 son of sevenless homolog 1 [Homo sapiens] 49 2e-05
gi|148806884 AKT1 substrate 1 (proline-rich) [Homo sapiens] 48 3e-05
gi|148806906 AKT1 substrate 1 (proline-rich) [Homo sapiens] 48 3e-05
gi|148806896 AKT1 substrate 1 (proline-rich) [Homo sapiens] 48 3e-05
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens] 48 3e-05
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 48 4e-05
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 47 5e-05
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 47 5e-05
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 47 5e-05
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 45 2e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 45 3e-04
>gi|190886435 RALBP1 associated Eps domain containing 1 isoform a
[Homo sapiens]
Length = 795
Score = 1597 bits (4135), Expect = 0.0
Identities = 795/795 (100%), Positives = 795/795 (100%)
Query: 1 MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATR 60
MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATR
Sbjct: 1 MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATR 60
Query: 61 LGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDS 120
LGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDS
Sbjct: 61 LGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDS 120
Query: 121 ENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRK 180
ENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRK
Sbjct: 121 ENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRK 180
Query: 181 HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTS 240
HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTS
Sbjct: 181 HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTS 240
Query: 241 TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDL 300
TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDL
Sbjct: 241 TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDL 300
Query: 301 NGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLP 360
NGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLP
Sbjct: 301 NGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLP 360
Query: 361 EKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQ 420
EKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQ
Sbjct: 361 EKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQ 420
Query: 421 WETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNP 480
WETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNP
Sbjct: 421 WETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNP 480
Query: 481 TSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSP 540
TSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSP
Sbjct: 481 TSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSP 540
Query: 541 DNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAV 600
DNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAV
Sbjct: 541 DNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAV 600
Query: 601 HRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKA 660
HRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKA
Sbjct: 601 HRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKA 660
Query: 661 SDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHT 720
SDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHT
Sbjct: 661 SDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHT 720
Query: 721 QKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERI 780
QKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERI
Sbjct: 721 QKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERI 780
Query: 781 SLEVQLEQLRPFSHL 795
SLEVQLEQLRPFSHL
Sbjct: 781 SLEVQLEQLRPFSHL 795
>gi|190886437 RALBP1 associated Eps domain containing 1 isoform b
[Homo sapiens]
Length = 769
Score = 1524 bits (3945), Expect = 0.0
Identities = 768/796 (96%), Positives = 768/796 (96%), Gaps = 28/796 (3%)
Query: 1 MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATR 60
MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATR
Sbjct: 1 MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATR 60
Query: 61 LGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDS 120
LGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDS
Sbjct: 61 LGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDS 120
Query: 121 ENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRK 180
ENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRK
Sbjct: 121 ENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRK 180
Query: 181 HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTS 240
HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTS
Sbjct: 181 HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTS 240
Query: 241 TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDL 300
TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDL
Sbjct: 241 TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDL 300
Query: 301 NGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLP 360
NGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLP
Sbjct: 301 NGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLP 360
Query: 361 EKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQ 420
EKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSE
Sbjct: 361 EKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSE- 419
Query: 421 WETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNP 480
DTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNP
Sbjct: 420 --------------------------DTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNP 453
Query: 481 TSPLLVKPSDLLEENKINSSVKFASGNTV-DGYSSSDSFTSDPEQIGSNVTRQRSHSGTS 539
TSPLLVKPSDLLEENKINSSVKFASGNTV DGYSSSDSFTSDPEQIGSNVTRQRSHSGTS
Sbjct: 454 TSPLLVKPSDLLEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGSNVTRQRSHSGTS 513
Query: 540 PDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPA 599
PDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPA
Sbjct: 514 PDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPA 573
Query: 600 VHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEK 659
VHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEK
Sbjct: 574 VHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEK 633
Query: 660 ASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEH 719
ASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEH
Sbjct: 634 ASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEH 693
Query: 720 TQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEER 779
TQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEER
Sbjct: 694 TQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEER 753
Query: 780 ISLEVQLEQLRPFSHL 795
ISLEVQLEQLRPFSHL
Sbjct: 754 ISLEVQLEQLRPFSHL 769
>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
[Homo sapiens]
Length = 659
Score = 350 bits (898), Expect = 3e-96
Identities = 271/812 (33%), Positives = 378/812 (46%), Gaps = 200/812 (24%)
Query: 4 LTLSDAEQKYYSDLFSYCD----------------IESTKKVVVNGRVLELFRAAQLPND 47
L LS+ EQ+ YS+LF+ C + G V +LFRA+QLP +
Sbjct: 28 LLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVADLFRASQLPAE 87
Query: 48 VVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNE 107
+ QI ELCGA R+GYFG +QFYIALKL+A AQSG P+R+ESI +LPLPRF+ SKN+
Sbjct: 88 TLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKC--ELPLPRFMMSKND 145
Query: 108 QESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSP 167
E R + + +E G+ + Q+ + ++ + D QE SP +SP
Sbjct: 146 GEIR----FGNPAELHGT----------KVQIPYLTTEKNSFKRMDDEDKQETQSPTMSP 191
Query: 168 QQSPPTSPHTWRK----HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSP 223
SPP+SP +++ H ++E+ P P + + SS G
Sbjct: 192 LASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGG--------- 242
Query: 224 PPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITD 283
P T L H AS+ + S + E++ SS D+PW+IT+
Sbjct: 243 -------------PGTKPL--RHQASL--------IRSFSVERELQDNSSYPDEPWRITE 279
Query: 284 EQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEF 343
EQR+YYVNQF+++QPD + FI GS AK FFTKSKL I ELS+IWELSD D DGALTL EF
Sbjct: 280 EQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEF 339
Query: 344 CAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPS 403
CAAFHL+VARKNGY LPE LP +L P+
Sbjct: 340 CAAFHLIVARKNGYPLPEGLPPTLQPEY-------------------------------- 367
Query: 404 MPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKI 463
L +P+ + ++++SE ++Q + + D A + PVP + S
Sbjct: 368 ---LQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL-PVPNQDVTSD- 422
Query: 464 HMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDPE 523
+ LK T ++ P D+ E+ N++ S S++
Sbjct: 423 --DKQALKSTINE---------ALPKDVSEDPATPK-----DSNSLKARPRSRSYS---- 462
Query: 524 QIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHP 583
S + G P P P PPRPQ +HSR+SSLD+N+ F + ++G++ P
Sbjct: 463 ---STSIEEAMKRGEDP----PTP-PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPP 514
Query: 584 PAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDE 643
PA+PPRP PSQ+ V L+ S +P Q A+ +
Sbjct: 515 PALPPRPCPSQS------EQVSEAELLPQLSRAPSQ-----------------AAESSPA 551
Query: 644 QDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVR 703
+ D P P + P + + E TAAS PA+
Sbjct: 552 KKDVLYSQPPSKPIRRKFRPEN-----QATENQEPSTAASGPAS---------------- 590
Query: 704 RRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLAR 763
AA + P++ + K KKAIQ +IR+NKE N VLAR
Sbjct: 591 -----------------------AATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLAR 627
Query: 764 LNSELQQQLKDVLEERISLEVQLEQLRPFSHL 795
LNSELQQQLK+V +ERI+LE QLEQLRP + L
Sbjct: 628 LNSELQQQLKEVHQERIALENQLEQLRPVTVL 659
>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
[Homo sapiens]
Length = 660
Score = 345 bits (886), Expect = 7e-95
Identities = 271/813 (33%), Positives = 378/813 (46%), Gaps = 201/813 (24%)
Query: 4 LTLSDAEQKYYSDLFSYCD----------------IESTKKVVVNGRVLELFRAAQLPND 47
L LS+ EQ+ YS+LF+ C + G V +LFRA+QLP +
Sbjct: 28 LLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVADLFRASQLPAE 87
Query: 48 VVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNE 107
+ QI ELCGA R+GYFG +QFYIALKL+A AQSG P+R+ESI +LPLPRF+ SKN+
Sbjct: 88 TLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKC--ELPLPRFMMSKND 145
Query: 108 QESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQ-EPASPVVS 166
E R + + +E G+ + Q+ + ++ + D Q E SP +S
Sbjct: 146 GEIR----FGNPAELHGT----------KVQIPYLTTEKNSFKRMDDEDKQQETQSPTMS 191
Query: 167 PQQSPPTSPHTWRK----HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHS 222
P SPP+SP +++ H ++E+ P P + + SS G
Sbjct: 192 PLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGG-------- 243
Query: 223 PPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKIT 282
P T L H AS+ + S + E++ SS D+PW+IT
Sbjct: 244 --------------PGTKPL--RHQASL--------IRSFSVERELQDNSSYPDEPWRIT 279
Query: 283 DEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDE 342
+EQR+YYVNQF+++QPD + FI GS AK FFTKSKL I ELS+IWELSD D DGALTL E
Sbjct: 280 EEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPE 339
Query: 343 FCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSP 402
FCAAFHL+VARKNGY LPE LP +L P+
Sbjct: 340 FCAAFHLIVARKNGYPLPEGLPPTLQPEY------------------------------- 368
Query: 403 SMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSK 462
L +P+ + ++++SE ++Q + + D A + PVP + S
Sbjct: 369 ----LQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL-PVPNQDVTSD 423
Query: 463 IHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDP 522
+ LK T ++ P D+ E+ N++ S S++
Sbjct: 424 ---DKQALKSTINE---------ALPKDVSEDPATPK-----DSNSLKARPRSRSYS--- 463
Query: 523 EQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAH 582
S + G P P P PPRPQ +HSR+SSLD+N+ F + ++G++
Sbjct: 464 ----STSIEEAMKRGEDP----PTP-PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPP 514
Query: 583 PPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVND 642
PPA+PPRP PSQ+ V L+ S +P Q A+ +
Sbjct: 515 PPALPPRPCPSQS------EQVSEAELLPQLSRAPSQ-----------------AAESSP 551
Query: 643 EQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPV 702
+ D P P + P + + E TAAS PA+
Sbjct: 552 AKKDVLYSQPPSKPIRRKFRPEN-----QATENQEPSTAASGPAS--------------- 591
Query: 703 RRRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLA 762
AA + P++ + K KKAIQ +IR+NKE N VLA
Sbjct: 592 ------------------------AATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 627
Query: 763 RLNSELQQQLKDVLEERISLEVQLEQLRPFSHL 795
RLNSELQQQLK+V +ERI+LE QLEQLRP + L
Sbjct: 628 RLNSELQQQLKEVHQERIALENQLEQLRPVTVL 660
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 72.0 bits (175), Expect = 2e-12
Identities = 121/535 (22%), Positives = 197/535 (36%), Gaps = 68/535 (12%)
Query: 277 DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 336
D W IT E+R + QF +++P ++GFI G A+ FF +S LP L+ IW L+D + DG
Sbjct: 13 DIWAITVEERAKHDQQFHSLKP-ISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDG 71
Query: 337 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEA 396
+ EF A L+ + GY LP LP + + + + + G G A
Sbjct: 72 RMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFG--------MGGIASM 123
Query: 397 PPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPI 456
PP + + P + P + S T S A P A P I
Sbjct: 124 PPLTAVA-PVPMGSIPVVGMSP----------------TLVSSVPTAAVPPLANGAPPVI 166
Query: 457 RMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSD 516
+ P+ H K + + P S L K S AS V ++
Sbjct: 167 QPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKA-------QSFDVASVPPVAEWAVPQ 219
Query: 517 SFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQ---PSHSRSSSLDMNRTFTV--- 570
S Q+ ++ + S T P PQ S S +D + T
Sbjct: 220 SSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEF 279
Query: 571 TTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTS-PQQIPEQPNFADF 629
V +PP P P P+ R G+ +STS Q++PE+P D
Sbjct: 280 ILAMHLIDVAMSGQPLPPVLPPEYIP-PSFRRVRSGSGISVISSTSVDQRLPEEPVLEDE 338
Query: 630 SQ---------FEVFAASNVNDEQDDEAEKHPEVL--PAEKASDPASSLRVAKTDSKTEE 678
Q FE N + + E EK + L K + + L A+ + K E
Sbjct: 339 QQQLEKKLPVTFEDKKRENF-ERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERE 397
Query: 679 KTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPR 738
+ + + ++L+ + EL + +E +K + R
Sbjct: 398 RQEQERKRQLE------------LEKQLEKQRELERQREEERRKEIERREAAKRELERQR 445
Query: 739 SVGKDKKAIQASI-RRNKETN--TVLARLNSELQQQLKDVLEERISLEVQLEQLR 790
+ ++ Q + +RNKE VL L+ +L+ + +++ LE +L+ +R
Sbjct: 446 QLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIR 500
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 72.0 bits (175), Expect = 2e-12
Identities = 121/535 (22%), Positives = 197/535 (36%), Gaps = 68/535 (12%)
Query: 277 DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 336
D W IT E+R + QF +++P ++GFI G A+ FF +S LP L+ IW L+D + DG
Sbjct: 13 DIWAITVEERAKHDQQFHSLKP-ISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDG 71
Query: 337 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEA 396
+ EF A L+ + GY LP LP + + + + + G G A
Sbjct: 72 RMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFG--------MGGIASM 123
Query: 397 PPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPI 456
PP + + P + P + S T S A P A P I
Sbjct: 124 PPLTAVA-PVPMGSIPVVGMSP----------------TLVSSVPTAAVPPLANGAPPVI 166
Query: 457 RMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSD 516
+ P+ H K + + P S L K S AS V ++
Sbjct: 167 QPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKA-------QSFDVASVPPVAEWAVPQ 219
Query: 517 SFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQ---PSHSRSSSLDMNRTFTV--- 570
S Q+ ++ + S T P PQ S S +D + T
Sbjct: 220 SSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEF 279
Query: 571 TTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTS-PQQIPEQPNFADF 629
V +PP P P P+ R G+ +STS Q++PE+P D
Sbjct: 280 ILAMHLIDVAMSGQPLPPVLPPEYIP-PSFRRVRSGSGISVISSTSVDQRLPEEPVLEDE 338
Query: 630 SQ---------FEVFAASNVNDEQDDEAEKHPEVL--PAEKASDPASSLRVAKTDSKTEE 678
Q FE N + + E EK + L K + + L A+ + K E
Sbjct: 339 QQQLEKKLPVTFEDKKRENF-ERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERE 397
Query: 679 KTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPR 738
+ + + ++L+ + EL + +E +K + R
Sbjct: 398 RQEQERKRQLE------------LEKQLEKQRELERQREEERRKEIERREAAKRELERQR 445
Query: 739 SVGKDKKAIQASI-RRNKETN--TVLARLNSELQQQLKDVLEERISLEVQLEQLR 790
+ ++ Q + +RNKE VL L+ +L+ + +++ LE +L+ +R
Sbjct: 446 QLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIR 500
>gi|7657056 EH-domain containing 3 [Homo sapiens]
Length = 535
Score = 71.2 bits (173), Expect = 3e-12
Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 1/94 (1%)
Query: 276 DDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKD 335
DD + + Y F T+ P ++G I G+ AK+ +SKLP L IW+L+D DKD
Sbjct: 435 DDAEWVVARDKPMYDEIFYTLSP-VDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKD 493
Query: 336 GALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
G L DEF A HL+ + G++LP +LP L+P
Sbjct: 494 GMLDDDEFALANHLIKVKLEGHELPNELPAHLLP 527
>gi|30240932 EH-domain containing 1 [Homo sapiens]
Length = 534
Score = 71.2 bits (173), Expect = 3e-12
Identities = 39/94 (41%), Positives = 54/94 (57%), Gaps = 1/94 (1%)
Query: 276 DDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKD 335
DD + + + Y F T+ P +NG I G+ AK+ KSKLP L IW+L+D DKD
Sbjct: 435 DDVEWVVGKDKPTYDEIFYTLSP-VNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKD 493
Query: 336 GALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
G L +EF A HL+ + G++LP LP L+P
Sbjct: 494 GLLDDEEFALANHLIKVKLEGHELPADLPPHLVP 527
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 70.9 bits (172), Expect = 4e-12
Identities = 45/131 (34%), Positives = 62/131 (47%), Gaps = 11/131 (8%)
Query: 239 TSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQP 298
+S L + P D T+ + S T+A E+ PW + E + Y F ++ P
Sbjct: 92 SSLNLAVPPPRFHD-TSSPLLISGTSAAEL---------PWAVKPEDKAKYDAIFDSLSP 141
Query: 299 DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD 358
+NGF+ G K SKLP+ L +WELSD D DG L DEF A LV
Sbjct: 142 -VNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEP 200
Query: 359 LPEKLPESLMP 369
+P LP +L+P
Sbjct: 201 VPMSLPPALVP 211
Score = 62.8 bits (151), Expect = 1e-09
Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 18/165 (10%)
Query: 279 WKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGAL 338
W ++ ++ Y F D++GF+ G +E F K+ LP L+HIW L D G L
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 339 TLDEFCAAFHLVVARK-NGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAP 397
+ D+F AFHL+ + G D P L P++I D A + + GS A
Sbjct: 278 SKDQFALAFHLISQKLIKGID----PPHVLTPEMIPPSDRASL-----QKNIIGSSPVAD 328
Query: 398 PSKSPSMPSLNQTWPELNQS--------SEQWETFSERSSSSQTL 434
S + +LN +L + E+ +T +R+S Q L
Sbjct: 329 FSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDL 373
Score = 46.6 bits (109), Expect = 9e-05
Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 289 YVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFH 348
Y ++ + G + S A F KS LP L L IW+L+D D G L EF A
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 349 LVVARKNGYDL----------PEKLPESLMPKLIDLEDSADV 380
LV +NG ++ P + ++ P LI +A++
Sbjct: 79 LVACAQNGLEVSLSSLNLAVPPPRFHDTSSPLLISGTSAAEL 120
Score = 45.1 bits (105), Expect = 3e-04
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 41/213 (19%)
Query: 4 LTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGY 63
LT + Y + D +T +V+ + L ++ LP+ ++ +I +L G
Sbjct: 9 LTQLSSGNPVYEKYYRQVDTGNTGRVLASDAAAFLKKSG-LPDLILGKIWDLADTDGKGI 67
Query: 64 FGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRF------------------VASK 105
+ +F++AL+LVA AQ+G + + S+N +P PRF A K
Sbjct: 68 LNKQEFFVALRLVACAQNGLEVSLSSLNLA--VPPPRFHDTSSPLLISGTSAAELPWAVK 125
Query: 106 NEQESRHAASYSSDSENQGSYSG--VIP-------PPPGRGQV-KKGSVSHDTVQPRTS- 154
E ++++ A + S S G SG V P P G+V + + HD + R
Sbjct: 126 PEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGMLDRDEF 185
Query: 155 ---------ADAQEPASPVVSPQQSPPTSPHTW 178
A +EP + P PP+ TW
Sbjct: 186 AVAMFLVYCALEKEPVPMSLPPALVPPSKRKTW 218
Score = 33.1 bits (74), Expect = 1.0
Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 6/152 (3%)
Query: 6 LSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFG 65
+S AE+ Y ++F D + V V E+F LP+ ++ I LC G
Sbjct: 220 VSPAEKAKYDEIFLKTD-KDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKLS 278
Query: 66 RSQFYIALKLVA--VAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQ 123
+ QF +A L++ + + P V + + P R KN S A +S+ E
Sbjct: 279 KDQFALAFHLISQKLIKGIDPPHVLTPEMIP--PSDRASLQKNIIGSSPVADFSAIKELD 336
Query: 124 GSYSGVIPPPPGRGQVKKG-SVSHDTVQPRTS 154
+ ++ + V++ DT++ RTS
Sbjct: 337 TLNNEIVDLQREKNNVEQDLKEKEDTIKQRTS 368
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 69.7 bits (169), Expect = 1e-11
Identities = 35/91 (38%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 279 WKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGAL 338
W + E++ + F+++ P +NG + G K SKLP+ L +W+LSD DKDG L
Sbjct: 121 WAVRVEEKAKFDGIFESLLP-INGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHL 179
Query: 339 TLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
DEF A HLV +P LP SL+P
Sbjct: 180 DRDEFAVAMHLVYRALEKEPVPSALPPSLIP 210
Score = 61.6 bits (148), Expect = 3e-09
Identities = 79/373 (21%), Positives = 146/373 (39%), Gaps = 48/373 (12%)
Query: 14 YSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVL-QIMELCGATRLGYFGRSQFYIA 72
Y + D T +V + L L ++ +D++L +I +L G+ + FY+A
Sbjct: 19 YESYYKQVDPAYTGRVGASEAALFLKKSGL--SDIILGKIWDLADPEGKGFLDKQGFYVA 76
Query: 73 LKLVAVAQSGFPLRVESINTVKDLPLPRF-------VASKNEQESRHAASYSSDSENQGS 125
L+LVA AQSG + + ++N +P P+F + + E+ A ++ G
Sbjct: 77 LRLVACAQSGHEVTLSNLNL--SMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGI 134
Query: 126 YSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPV--------VSPQQSPPTSPHT 177
+ ++P G +S D V+P +++ P + +
Sbjct: 135 FESLLPI--------NGLLSGDKVKP-VLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFA 185
Query: 178 WRKHSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTP 237
H + + P A P P S V+ G P P A P
Sbjct: 186 VAMHLVYRALEKEPVPSALPPSLIPP-------SKRKKTVFPGAVPVLP-------ASPP 231
Query: 238 PTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQ 297
P +L + S +++ + S + +++ + + W + + + F
Sbjct: 232 PKDSLRST--PSHGSVSSLNSTGSLSPKHSLKQTQPTVN--WVVPVADKMRFDEIFLKTD 287
Query: 298 PDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVAR-KNG 356
DL+G++ G KE F S L L+HIW L+D + G L+ D+F A + + + G
Sbjct: 288 LDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKG 347
Query: 357 YDLPEKLPESLMP 369
D P+ L ++P
Sbjct: 348 IDPPQVLSPDMVP 360
>gi|21361462 EH-domain containing 2 [Homo sapiens]
Length = 543
Score = 68.6 bits (166), Expect = 2e-11
Identities = 39/105 (37%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 265 AIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELS 324
A+E + S + W +T ++ +Y F + P +G + GS AK + +KLP L
Sbjct: 430 AMEDGEEGSDDEAEWVVTKDKSKYD-EIFYNLAP-ADGKLSGSKAKTWMVGTKLPNSVLG 487
Query: 325 HIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
IW+LSD D+DG L +EF A HL+ A+ G+ LP LP L+P
Sbjct: 488 RIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVP 532
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 68.2 bits (165), Expect = 3e-11
Identities = 35/86 (40%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Query: 279 WKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGAL 338
W IT E+R + QF ++P G+I G A+ FF +S LP L+ IW LSD +KDG +
Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74
Query: 339 TLDEFCAAFHLVVARKNGYDLPEKLP 364
EF A L+ + G LP LP
Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLP 100
Score = 65.9 bits (159), Expect = 1e-10
Identities = 77/345 (22%), Positives = 127/345 (36%), Gaps = 61/345 (17%)
Query: 30 VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVES 89
+ + F + LP V+ +I L + G + +F IA+KL+ + G L V
Sbjct: 40 ITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVL 99
Query: 90 INTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTV 149
+K P+ +S +I G G + S+
Sbjct: 100 PPIMKQPPM---------------------------FSPLISARFGMGSMPNLSI----- 127
Query: 150 QPRTSADAQEPASPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPFGEAQS 209
PQ PP +P T + + G + PL P +P + S
Sbjct: 128 -----------------PQPLPPAAPITSLSSA---TSGTNLPPLMMP----TPLVPSVS 163
Query: 210 GSSAGDAVWSGHSPPPPQENWVSFADTPPTSTLLT-MHPASVQDQTTVRTVASATTAIEI 268
SS + S P P + + S ++ AS+Q ++ + S+++
Sbjct: 164 TSSLPNGTASLIQPLPIPYSSSTLPHGSSYSLMMGGFGGASIQKAQSLIDLGSSSSTSST 223
Query: 269 RRQSSSYD----DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELS 324
S + W + R Y +F T+ ++G++ G A+ +S L +L+
Sbjct: 224 ASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLA 283
Query: 325 HIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
IW L+D D DG L +EF A HL K G LP LP L+P
Sbjct: 284 TIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVP 328
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 68.2 bits (165), Expect = 3e-11
Identities = 35/86 (40%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Query: 279 WKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGAL 338
W IT E+R + QF ++P G+I G A+ FF +S LP L+ IW LSD +KDG +
Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74
Query: 339 TLDEFCAAFHLVVARKNGYDLPEKLP 364
EF A L+ + G LP LP
Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLP 100
Score = 65.9 bits (159), Expect = 1e-10
Identities = 77/345 (22%), Positives = 127/345 (36%), Gaps = 61/345 (17%)
Query: 30 VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVES 89
+ + F + LP V+ +I L + G + +F IA+KL+ + G L V
Sbjct: 40 ITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVL 99
Query: 90 INTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTV 149
+K P+ +S +I G G + S+
Sbjct: 100 PPIMKQPPM---------------------------FSPLISARFGMGSMPNLSI----- 127
Query: 150 QPRTSADAQEPASPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPFGEAQS 209
PQ PP +P T + + G + PL P +P + S
Sbjct: 128 -----------------PQPLPPAAPITSLSSA---TSGTNLPPLMMP----TPLVPSVS 163
Query: 210 GSSAGDAVWSGHSPPPPQENWVSFADTPPTSTLLT-MHPASVQDQTTVRTVASATTAIEI 268
SS + S P P + + S ++ AS+Q ++ + S+++
Sbjct: 164 TSSLPNGTASLIQPLPIPYSSSTLPHGSSYSLMMGGFGGASIQKAQSLIDLGSSSSTSST 223
Query: 269 RRQSSSYD----DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELS 324
S + W + R Y +F T+ ++G++ G A+ +S L +L+
Sbjct: 224 ASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLA 283
Query: 325 HIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
IW L+D D DG L +EF A HL K G LP LP L+P
Sbjct: 284 TIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVP 328
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 68.2 bits (165), Expect = 3e-11
Identities = 35/86 (40%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Query: 279 WKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGAL 338
W IT E+R + QF ++P G+I G A+ FF +S LP L+ IW LSD +KDG +
Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74
Query: 339 TLDEFCAAFHLVVARKNGYDLPEKLP 364
EF A L+ + G LP LP
Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLP 100
Score = 65.9 bits (159), Expect = 1e-10
Identities = 77/345 (22%), Positives = 127/345 (36%), Gaps = 61/345 (17%)
Query: 30 VVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVES 89
+ + F + LP V+ +I L + G + +F IA+KL+ + G L V
Sbjct: 40 ITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVL 99
Query: 90 INTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTV 149
+K P+ +S +I G G + S+
Sbjct: 100 PPIMKQPPM---------------------------FSPLISARFGMGSMPNLSI----- 127
Query: 150 QPRTSADAQEPASPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPFGEAQS 209
PQ PP +P T + + G + PL P +P + S
Sbjct: 128 -----------------PQPLPPAAPITSLSSA---TSGTNLPPLMMP----TPLVPSVS 163
Query: 210 GSSAGDAVWSGHSPPPPQENWVSFADTPPTSTLLT-MHPASVQDQTTVRTVASATTAIEI 268
SS + S P P + + S ++ AS+Q ++ + S+++
Sbjct: 164 TSSLPNGTASLIQPLPIPYSSSTLPHGSSYSLMMGGFGGASIQKAQSLIDLGSSSSTSST 223
Query: 269 RRQSSSYD----DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELS 324
S + W + R Y +F T+ ++G++ G A+ +S L +L+
Sbjct: 224 ASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLA 283
Query: 325 HIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
IW L+D D DG L +EF A HL K G LP LP L+P
Sbjct: 284 TIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVP 328
>gi|21264315 EH-domain containing 4 [Homo sapiens]
Length = 541
Score = 67.0 bits (162), Expect = 6e-11
Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
Query: 276 DDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKD 335
++ W + + + Y F T+ P +NG I G AK+ SKLP L IW+L+D D D
Sbjct: 439 EEEWVVAKD-KPVYDELFYTLSP-INGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCD 496
Query: 336 GALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
G L +EF A HL+ + +GY+LP LP L+P
Sbjct: 497 GMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVP 530
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 53.9 bits (128), Expect = 6e-07
Identities = 46/165 (27%), Positives = 67/165 (40%), Gaps = 13/165 (7%)
Query: 479 NPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGT 538
+P S + P + E+ + S F+ T+ +S D ++ P V SGT
Sbjct: 2092 DPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGT 2151
Query: 539 SPDNTAP---PPPPPRP--------QPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVP 587
+ NT P PP PRP QP R S+ + T T Q+ + AHPP P
Sbjct: 2152 ARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPST-QTDLFVTPVTNQRHSDPYAHPPGTP 2210
Query: 588 -PRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQ 631
P + PA RP ++G + T P +P Q F +Q
Sbjct: 2211 RPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQ 2255
Score = 35.0 bits (79), Expect = 0.27
Identities = 86/400 (21%), Positives = 139/400 (34%), Gaps = 50/400 (12%)
Query: 390 SGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAP--ADPD 447
SGS + +SP P QS + E F+++ S+ T T D A P
Sbjct: 1797 SGSDTPSSGIQSPLTPQPGNGNMSPAQSFHK-ELFTKQPPSTPTSTSSDDVFVKPQAPPP 1855
Query: 448 TAIVHPVPIRMTPSKIHMQEM---ELKRTGSDHTNPTSPL--------LVKPSDLLEE-N 495
+PI+ + S+ + ++ GS ++ P SP+ +P + +
Sbjct: 1856 PPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFS 1915
Query: 496 KINSSVKFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPS 555
+ NS+ + + S S V S S T+ D A PP PRP +
Sbjct: 1916 RRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMT 1975
Query: 556 HSRSSSLDMNRTFTVT----TGQQQAGVVAHPPAVPPRPQ--PSQAPGPAVHRPVDADGL 609
SL ++R+ V+ G AG H PR Q + RP+
Sbjct: 1976 DQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAP 2035
Query: 610 ITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPA-----------E 658
+ + P + P QP SQ + S + + + P + P +
Sbjct: 2036 L-DSGPGPFKTPMQP--PPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSND 2092
Query: 659 KASDPASSLRVAKTDSKTEEKTAASAPANVSKGTT--PLAPPPKPVRRRLKSEDELRPEV 716
S P + A +S A S P +S+ T+ P + PP RP V
Sbjct: 2093 PYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPP----------GTPRPVV 2142
Query: 717 DEHTQKTGVLAA---VLASQPSIPRSVGKDKKAIQASIRR 753
D ++Q +G + + P PR D + Q R
Sbjct: 2143 DSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPR 2182
Score = 32.3 bits (72), Expect = 1.8
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 8/84 (9%)
Query: 710 DELRPEVDEHTQKTGVLAAVLASQPSIPRSVG---KDKKAIQASIRRNKETNTVLARLNS 766
D R + +E Q+T L + Q + +G K KKA+ A R K+ ++
Sbjct: 3174 DSQRKQYEEWLQETQQLLQM--QQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDA 3231
Query: 767 ELQQQLKDVLEERISLEVQLEQLR 790
E QLK V E++ ++ QLEQ+R
Sbjct: 3232 E---QLKHVTEQQSMVQKQLEQIR 3252
>gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo
sapiens]
Length = 1075
Score = 50.1 bits (118), Expect = 8e-06
Identities = 85/415 (20%), Positives = 143/415 (34%), Gaps = 59/415 (14%)
Query: 357 YDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSK----SPSMPSLNQTWP 412
YD +P + KLI + V + SP +AP +P LN+T
Sbjct: 233 YDQDHTVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTV 292
Query: 413 ELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPV---PIRMTPSKIHMQEME 469
+L S F + L + ++ PA+ T V + P +TP +
Sbjct: 293 KLPASL----MFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKP 348
Query: 470 LKRTGSDHTNPT-----SPLLVKPSDLLEENKINSSVK-----FASGNTVDGYSSSDSFT 519
+ D + T P +V + + E++K+ F+S T D SDS+T
Sbjct: 349 TTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYT 408
Query: 520 SDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGV 579
+ ++I ++ + S + P T P P +S +M T T QQ
Sbjct: 409 ATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPT---TPAPQQTTS 465
Query: 580 VAHPPAVPPRPQP------------------SQAPGPAVHRP-------------VDADG 608
+ P PRP+P S++P P P +
Sbjct: 466 IPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSP 525
Query: 609 LITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPASSLR 668
+THT +P+Q P P S + + P+ P+ + S + +
Sbjct: 526 EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 585
Query: 669 VAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKT 723
K + + S PA + P P P S++EL+ ++E Q T
Sbjct: 586 DVLLPHKPYPEVSQSEPAPLETRGIPFIPMISP----SPSQEELQTTLEETDQST 636
Score = 38.1 bits (87), Expect = 0.032
Identities = 43/178 (24%), Positives = 62/178 (34%), Gaps = 20/178 (11%)
Query: 522 PEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVA 581
P NV+ +H P PP P P+P+H R L N VT AG+++
Sbjct: 684 PSGADRNVSVDSTHPTKKPGTRRPPLP---PRPTHPRRKPLPPN---NVTGKPGSAGIIS 737
Query: 582 HPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVN 641
P P + + P ++ D T P E N DFS + +
Sbjct: 738 SGPITTPPLRSTPRPTGTPLERIETD---IKQPTVPASGEELENITDFSS----SPTRET 790
Query: 642 DEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPP 699
D K P V +K + S+ + EE T +A T+P PP
Sbjct: 791 DPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNA-------TSPPQNPP 841
>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
Length = 1812
Score = 50.1 bits (118), Expect = 8e-06
Identities = 54/216 (25%), Positives = 82/216 (37%), Gaps = 28/216 (12%)
Query: 478 TNPTSPLLVKPSDLLEENKINSSVKFASGNTV--DGYSSSDSFTSDPEQIGSNVTRQRSH 535
+ P++P+ + L E N+S+ F + V DG + I +V R SH
Sbjct: 77 SKPSAPVFDRLGSL--EYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISH 134
Query: 536 SGTSPDNTAPPPPPPRPQPSHSRS---SSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQP 592
SP PPPPPP+PQPS R+ + + F + + Q PP PP
Sbjct: 135 DRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDD 194
Query: 593 SQAPGPAVHRPVDAD---------GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDE 643
P P PV D S +P++ ++D V +E
Sbjct: 195 EDDPVPL---PVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSD--------EGEVEEE 243
Query: 644 QDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEK 679
Q +E E+ + + E+ D R DS EE+
Sbjct: 244 QQEEGEEDEDDVDVEEEEDEDEDDR-RTVDSIPEEE 278
Score = 30.0 bits (66), Expect = 8.8
Identities = 28/114 (24%), Positives = 43/114 (37%), Gaps = 12/114 (10%)
Query: 101 FVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQ--VKKGSVSHDTVQPRTSADAQ 158
F K++ E+ +S S+ + V+PPP GRG+ +G HD + R ++
Sbjct: 1589 FKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSR 1648
Query: 159 EPA----------SPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWS 202
P+ S V PQ P + + S G G G F S
Sbjct: 1649 PPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHS 1702
>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
Length = 1147
Score = 50.1 bits (118), Expect = 8e-06
Identities = 54/216 (25%), Positives = 82/216 (37%), Gaps = 28/216 (12%)
Query: 478 TNPTSPLLVKPSDLLEENKINSSVKFASGNTV--DGYSSSDSFTSDPEQIGSNVTRQRSH 535
+ P++P+ + L E N+S+ F + V DG + I +V R SH
Sbjct: 77 SKPSAPVFDRLGSL--EYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISH 134
Query: 536 SGTSPDNTAPPPPPPRPQPSHSRS---SSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQP 592
SP PPPPPP+PQPS R+ + + F + + Q PP PP
Sbjct: 135 DRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDD 194
Query: 593 SQAPGPAVHRPVDAD---------GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDE 643
P P PV D S +P++ ++D V +E
Sbjct: 195 EDDPVPL---PVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSD--------EGEVEEE 243
Query: 644 QDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEK 679
Q +E E+ + + E+ D R DS EE+
Sbjct: 244 QQEEGEEDEDDVDVEEEEDEDEDDR-RTVDSIPEEE 278
>gi|15529996 son of sevenless homolog 1 [Homo sapiens]
Length = 1333
Score = 48.9 bits (115), Expect = 2e-05
Identities = 73/292 (25%), Positives = 112/292 (38%), Gaps = 57/292 (19%)
Query: 441 IAPADPDTAIV-HPVPIRMTPSKI---HMQEMELKRTGSDHTNPTSPLLVKPSDLLEENK 496
+ P++P + HP P++ P KI + E E + T S +P +PL P+
Sbjct: 1040 VRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPAS------ 1093
Query: 497 INSSVKFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSH 556
+ +T D S DS S P S+ T P P
Sbjct: 1094 -------GASSTTDVCSVFDSDHSSPFH--------SSNDTVFIQVTLPHGP-------- 1130
Query: 557 SRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTS 616
RS+S+ + ++T G + V PP VPPR +P AP + + + H +
Sbjct: 1131 -RSASVS---SISLTKGTDEVPV---PPPVPPRRRPESAPAESSPSKI----MSKHLDSP 1179
Query: 617 PQQIPEQPNFADFS-QFEVFAASNVNDEQDDEAEKHPEVLPAEKASDP----ASSLRVAK 671
P P QP +S ++ + ++++ D E P + P E P +S L +
Sbjct: 1180 PAIPPRQPTSKAYSPRYSISDRTSIS----DPPESPPLLPPREPVRTPDVFSSSPLHLQP 1235
Query: 672 TD-SKTEEKTAASAPANVSKGT--TPLAPPPKPVRRRLKSEDELRPEVDEHT 720
K + A P + S T P P P RR L S L EVD H+
Sbjct: 1236 PPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPS-PPLTQEVDLHS 1286
Score = 33.9 bits (76), Expect = 0.61
Identities = 36/156 (23%), Positives = 56/156 (35%), Gaps = 23/156 (14%)
Query: 454 VPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYS 513
+P R SK + + S P SP L+ P + + T D +S
Sbjct: 1182 IPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVR--------------TPDVFS 1227
Query: 514 SSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPP-PRPQ------PSHSRSSSLDMNR 566
SS P +G + SP PPPP P P PS + +D++
Sbjct: 1228 SSPLHLQPPP-LGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHS 1286
Query: 567 TFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHR 602
+Q+ H P +PP+ + P++HR
Sbjct: 1287 IAGPPVPPRQS-TSQHIPKLPPKTYKREHTHPSMHR 1321
Score = 31.2 bits (69), Expect = 3.9
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 6/69 (8%)
Query: 132 PPPGRGQVKKGSVSHDTVQPRTS-ADAQEPASPVVSPQQS-----PPTSPHTWRKHSRHP 185
PPP + G+ H P T D A P V P+QS P P T+++ HP
Sbjct: 1258 PPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHP 1317
Query: 186 SGGNSERPL 194
S PL
Sbjct: 1318 SMHRDGPPL 1326
>gi|148806884 AKT1 substrate 1 (proline-rich) [Homo sapiens]
Length = 256
Score = 48.1 bits (113), Expect = 3e-05
Identities = 67/250 (26%), Positives = 96/250 (38%), Gaps = 47/250 (18%)
Query: 543 TAPPPPPPRPQP----SHSRSSSLD-MNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPG 597
TA PPPPPRP P +H R + + R +A A PPA PP PQP +P
Sbjct: 32 TAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIALAHRAATAARPPAPPPAPQP-PSPT 90
Query: 598 PAVHRPV-------DADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEK 650
P+ RP + + T T TS +Q+ N F V DE +
Sbjct: 91 PSPPRPTLAREDNEEDEDEPTETETSGEQLGISDNGGLF----------VMDE-----DA 135
Query: 651 HPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPK--PVRRRLKS 708
+ LP SDP S+ D E+T A P T PP P ++ KS
Sbjct: 136 TLQDLPPFCESDPEST-----DDGSLSEETPAGPP-------TCSVPPASALPTQQYAKS 183
Query: 709 EDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLA-----R 763
P ++T ++ + P + + +++A + R E V R
Sbjct: 184 LPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPR 243
Query: 764 LNSELQQQLK 773
LN+ Q+LK
Sbjct: 244 LNTSDFQKLK 253
>gi|148806906 AKT1 substrate 1 (proline-rich) [Homo sapiens]
Length = 256
Score = 48.1 bits (113), Expect = 3e-05
Identities = 67/250 (26%), Positives = 96/250 (38%), Gaps = 47/250 (18%)
Query: 543 TAPPPPPPRPQP----SHSRSSSLD-MNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPG 597
TA PPPPPRP P +H R + + R +A A PPA PP PQP +P
Sbjct: 32 TAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIALAHRAATAARPPAPPPAPQP-PSPT 90
Query: 598 PAVHRPV-------DADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEK 650
P+ RP + + T T TS +Q+ N F V DE +
Sbjct: 91 PSPPRPTLAREDNEEDEDEPTETETSGEQLGISDNGGLF----------VMDE-----DA 135
Query: 651 HPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPK--PVRRRLKS 708
+ LP SDP S+ D E+T A P T PP P ++ KS
Sbjct: 136 TLQDLPPFCESDPEST-----DDGSLSEETPAGPP-------TCSVPPASALPTQQYAKS 183
Query: 709 EDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLA-----R 763
P ++T ++ + P + + +++A + R E V R
Sbjct: 184 LPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPR 243
Query: 764 LNSELQQQLK 773
LN+ Q+LK
Sbjct: 244 LNTSDFQKLK 253
>gi|148806896 AKT1 substrate 1 (proline-rich) [Homo sapiens]
Length = 256
Score = 48.1 bits (113), Expect = 3e-05
Identities = 67/250 (26%), Positives = 96/250 (38%), Gaps = 47/250 (18%)
Query: 543 TAPPPPPPRPQP----SHSRSSSLD-MNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPG 597
TA PPPPPRP P +H R + + R +A A PPA PP PQP +P
Sbjct: 32 TAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIALAHRAATAARPPAPPPAPQP-PSPT 90
Query: 598 PAVHRPV-------DADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEK 650
P+ RP + + T T TS +Q+ N F V DE +
Sbjct: 91 PSPPRPTLAREDNEEDEDEPTETETSGEQLGISDNGGLF----------VMDE-----DA 135
Query: 651 HPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPK--PVRRRLKS 708
+ LP SDP S+ D E+T A P T PP P ++ KS
Sbjct: 136 TLQDLPPFCESDPEST-----DDGSLSEETPAGPP-------TCSVPPASALPTQQYAKS 183
Query: 709 EDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLA-----R 763
P ++T ++ + P + + +++A + R E V R
Sbjct: 184 LPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPR 243
Query: 764 LNSELQQQLK 773
LN+ Q+LK
Sbjct: 244 LNTSDFQKLK 253
>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
Length = 1858
Score = 48.1 bits (113), Expect = 3e-05
Identities = 54/222 (24%), Positives = 72/222 (32%), Gaps = 17/222 (7%)
Query: 384 PGEVGYSGSPAEAPPSKSPSMPS--LNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNI 441
PGE Y P P S L+ P L + + E + F N+
Sbjct: 1427 PGESVYEEMKCCLPDDGGPGAGSFLLHGASPPLLHRAPEDEAAGPPGDACDIPPPFP-NL 1485
Query: 442 APADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSV 501
P P + P P+ +P+ SD + P +PL VK +LE N
Sbjct: 1486 LPHRPPLLVFPPTPVTCSPA-------------SDES-PLTPLEVKKLPVLETNLKYPVQ 1531
Query: 502 KFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSS 561
S YS S D S + P PPPPPP P P+ R +
Sbjct: 1532 PEGSSPLSPQYSKSQKGDGDRPASPGLALFNGSGRASPPSTPPPPPPPPGPPPAPYRPCA 1591
Query: 562 LDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRP 603
+AG A P V P+P + GP P
Sbjct: 1592 HLAFPPEPAPVNAGKAGPSAEAPKVHPKPNSAPVAGPCSSFP 1633
Score = 36.6 bits (83), Expect = 0.094
Identities = 44/161 (27%), Positives = 59/161 (36%), Gaps = 27/161 (16%)
Query: 554 PSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHT 613
P +S+S D +R + A PP+ PP P P P PA +RP H
Sbjct: 1540 PQYSKSQKGDGDRPASPGLALFNGSGRASPPSTPPPPPPPPGPPPAPYRP------CAHL 1593
Query: 614 STSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEK-HPEVLPAEKASDPASSLRVAKT 672
+ P+ P A S EA K HP+ A A +S ++ +
Sbjct: 1594 AFPPEPAPVNAGKAGPSA---------------EAPKVHPKPNSAPVAGPCSSFPKIPYS 1638
Query: 673 DSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSE-DEL 712
K A A ++ S P AP P R L S DEL
Sbjct: 1639 PVKATRADARKAGSSAS----PPAPYSPPSSRPLSSPLDEL 1675
>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
sapiens]
Length = 817
Score = 47.8 bits (112), Expect = 4e-05
Identities = 65/315 (20%), Positives = 107/315 (33%), Gaps = 49/315 (15%)
Query: 385 GEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPA 444
GE G AEAP + + LN++ + +S S+ +++FDS AP+
Sbjct: 72 GEAGGGAGLAEAPRASERGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPS 131
Query: 445 DPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFA 504
HP P R+ ++ + G D LL + L++ K++ V+F
Sbjct: 132 AQPAPPPHP-PSRLQETRKLFERSAPAAAGGDKEAAARRLLRQERAGLQDRKLDVVVRFN 190
Query: 505 SGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAP------------------- 545
+D+ + Q+ + + S +G P
Sbjct: 191 GSTEALDKLDADAVSPTVSQLSAVFEKADSRTGLHRGPGLPRAAGVPQVNSKLVSKRSRV 250
Query: 546 --PPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRP------------- 590
PPPPP P PS + + GQQ P PP+P
Sbjct: 251 FQPPPPPPPAPSGDAPAEKE-----RCPAGQQPPQHRVAPARPPPKPREVRKIKPVEVEE 305
Query: 591 ----QPSQAPGPAVHRPVDADGLITHTS---TSPQQIPEQPNFADFSQFEVFAASNVNDE 643
+ APG + V + + S T+ PE+P + E AA+ E
Sbjct: 306 SGESEAESAPGEVIQAEVTVHAALENGSTVATAASPAPEEPKAQAAPEKE--AAAVAPPE 363
Query: 644 QDDEAEKHPEVLPAE 658
+ + P+V P E
Sbjct: 364 RGVGNGRAPDVAPEE 378
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 47.4 bits (111), Expect = 5e-05
Identities = 70/317 (22%), Positives = 116/317 (36%), Gaps = 28/317 (8%)
Query: 392 SPAEAP--PSKSPSMPSLNQTWPELNQSSEQWE-TFSERSSSSQTLTQFDSNIAPADPDT 448
SP+ +P PS SP+ PS + T P + +S + T S +S + + + +P P
Sbjct: 1612 SPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1671
Query: 449 AIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNT 508
+ P +PS S +PTSP S + S S +
Sbjct: 1672 SPTSPSYSPTSPSY---------SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1722
Query: 509 VDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTF 568
S S + P + T ++S TSP+ T P PS+S +S +
Sbjct: 1723 TSPSYSPTSPSYSPTSPSYSPTSP-NYSPTSPNYTPTSPSYSPTSPSYSPTSP-----NY 1776
Query: 569 TVTTGQQQAGVVAHPPAVPPRP--QPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNF 626
T T+ ++ P P PS +P + P T+T +SP P P++
Sbjct: 1777 TPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSP----TYTPSSPSYSPSSPSY 1832
Query: 627 ADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPASS--LRVAKTDSKTEEKTAASA 684
+ S + + + + P+ P P S + T S T K + ++
Sbjct: 1833 SPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTS 1892
Query: 685 PANVSKGTTPLAPPPKP 701
P T+P+ P P
Sbjct: 1893 P--TYSPTSPVYTPTSP 1907
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 47.4 bits (111), Expect = 5e-05
Identities = 69/304 (22%), Positives = 121/304 (39%), Gaps = 42/304 (13%)
Query: 393 PAEAPPSKSPSM---PSLNQTWPELNQSSEQWETF--SERSSSSQTLTQFDSNIAPADPD 447
P PP + S+ P L P L + + +T +R+S Q T F P P
Sbjct: 547 PPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAAT-FGELSGPLKPG 605
Query: 448 TAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGN 507
+ PVP P+ I+ + ++ +R LV DL E + + K +
Sbjct: 606 SPYRPPVPRAPDPAYIYDEFLQQRRR-----------LVSKLDLEERRRREAQEKGYYYD 654
Query: 508 TVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRT 567
D Y SD E++ +++ PP + S S L+ +
Sbjct: 655 LDDSYDESDE-----EEVRAHL------------RCVAEQPPLKLDTS---SEKLEFLQL 694
Query: 568 FTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAV---HRPVDADGLITHTSTSPQQIPEQP 624
F +TT QQ+ +VA R ++P P R + L T SP ++ P
Sbjct: 695 FGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSP 754
Query: 625 NFADFSQF-EVFAASNVNDEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAA- 682
NF + +F +F ++++ E+ + E+ E+L A K ++++ + T+S + +
Sbjct: 755 NFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSL 814
Query: 683 SAPA 686
S PA
Sbjct: 815 SEPA 818
Score = 31.2 bits (69), Expect = 3.9
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 18/77 (23%)
Query: 541 DNTAPPPPPPRPQPSHSRSSSL--------DMNRTFTVTTGQQQA--------GVVAHP- 583
D PPPPPPR S L ++ ++ GQQ+A G ++ P
Sbjct: 543 DKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPL 602
Query: 584 -PAVPPRPQPSQAPGPA 599
P P RP +AP PA
Sbjct: 603 KPGSPYRPPVPRAPDPA 619
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 47.4 bits (111), Expect = 5e-05
Identities = 69/304 (22%), Positives = 121/304 (39%), Gaps = 42/304 (13%)
Query: 393 PAEAPPSKSPSM---PSLNQTWPELNQSSEQWETF--SERSSSSQTLTQFDSNIAPADPD 447
P PP + S+ P L P L + + +T +R+S Q T F P P
Sbjct: 651 PPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAAT-FGELSGPLKPG 709
Query: 448 TAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGN 507
+ PVP P+ I+ + ++ +R LV DL E + + K +
Sbjct: 710 SPYRPPVPRAPDPAYIYDEFLQQRRR-----------LVSKLDLEERRRREAQEKGYYYD 758
Query: 508 TVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRT 567
D Y SD E++ +++ PP + S S L+ +
Sbjct: 759 LDDSYDESDE-----EEVRAHL------------RCVAEQPPLKLDTS---SEKLEFLQL 798
Query: 568 FTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAV---HRPVDADGLITHTSTSPQQIPEQP 624
F +TT QQ+ +VA R ++P P R + L T SP ++ P
Sbjct: 799 FGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSP 858
Query: 625 NFADFSQF-EVFAASNVNDEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAA- 682
NF + +F +F ++++ E+ + E+ E+L A K ++++ + T+S + +
Sbjct: 859 NFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSL 918
Query: 683 SAPA 686
S PA
Sbjct: 919 SEPA 922
Score = 31.2 bits (69), Expect = 3.9
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 18/77 (23%)
Query: 541 DNTAPPPPPPRPQPSHSRSSSL--------DMNRTFTVTTGQQQA--------GVVAHP- 583
D PPPPPPR S L ++ ++ GQQ+A G ++ P
Sbjct: 647 DKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPL 706
Query: 584 -PAVPPRPQPSQAPGPA 599
P P RP +AP PA
Sbjct: 707 KPGSPYRPPVPRAPDPA 723
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 45.4 bits (106), Expect = 2e-04
Identities = 63/292 (21%), Positives = 111/292 (38%), Gaps = 34/292 (11%)
Query: 337 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPK---LIDLEDSADVGDQPGEVGYSGSP 393
+LT+ A+ R + +P + + MP L ++ +A + +G+P
Sbjct: 165 SLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTP 224
Query: 394 AEAPPSKSPSMPSLN---------QTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPA 444
A P+ SP SL+ +T P + + T + S+ ++T+ S + A
Sbjct: 225 PRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTA 284
Query: 445 DPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSV-KF 503
P T + MTPS + M + + + + TS + + + +S+ +
Sbjct: 285 SP-TGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRT 343
Query: 504 ASGNTVDGYSSSDSFTSDPEQI---GSNVTRQRSHSGTSPDNTAPPP------------- 547
S + G S+ S T P + GS T + ++ T PP
Sbjct: 344 PSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASL 403
Query: 548 --PPPRPQPSH--SRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQA 595
PPR P+ SR+S M+ T + T +A PP P PS+A
Sbjct: 404 TRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRA 455
Score = 43.1 bits (100), Expect = 0.001
Identities = 72/344 (20%), Positives = 125/344 (36%), Gaps = 28/344 (8%)
Query: 377 SADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQ 436
+A + P +G+P+ A +PS SL T P + S S +LT+
Sbjct: 19 TASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVSPSRASLTR 78
Query: 437 F-DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEEN 495
S++ P A + +P R + ++ + L R S + SP +
Sbjct: 79 MQSSSLLTRTPSMASLKRMPPRASRTRT-LPRASLMRRPSTASLTRSPSRASLTTTPSRA 137
Query: 496 KINSSVKFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPS 555
++ + A+ T+ S S T P + +T + +P +P P R P+
Sbjct: 138 SLSMTPSTAAALTM---PSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPT 194
Query: 556 --HSRSSSLDMNRTFTVTTGQQQAGVVAHPPAV-----PPRPQPSQAPGPA--VHRPVDA 606
S +S M+ T ++T +A PP PPR S P A + P A
Sbjct: 195 GMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRA 254
Query: 607 D--GLITHTS-------TSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPA 657
G+++ TS S + P +P+ A S + +LP
Sbjct: 255 SPTGMLSRTSLTKMDSTASITRTPSRPSTAS----PTGTPSRASLSMTPSTASLMRMLPR 310
Query: 658 EKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKP 701
+ S + K DS T + A++++ + +P KP
Sbjct: 311 ASPTGMLSRTSLTKMDS-TASISRTPPRASITRTPSRASPTGKP 353
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/235 (24%), Positives = 83/235 (35%), Gaps = 35/235 (14%)
Query: 375 EDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTL 434
+ +A P +GSP+ A P+ SPS SL +T + + + R+ S +
Sbjct: 461 QSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASP 520
Query: 435 TQFDSNIAP-ADPDTAIVHPVPIR----MTPSKIHMQEMELKRTGS--DHTNPTSPLLVK 487
T S +P P TA+ P R TPS+ L RT S T P+ L +
Sbjct: 521 TWTPSTASPTGSPSTALAMGSPSRAALTRTPSR-----ASLTRTPSRASLTTPSRASLTR 575
Query: 488 -PSDLLEENKINSS--VKFASGNTVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTA 544
PS +L S+ S + G SS T T R+ +P +
Sbjct: 576 TPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRAS 635
Query: 545 PPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPA 599
P PPR P+ + A P PPR P+ P A
Sbjct: 636 PTGTPPRASPTGTPPR--------------------ASPTGTPPRASPTGTPSRA 670
Score = 35.4 bits (80), Expect = 0.21
Identities = 58/250 (23%), Positives = 87/250 (34%), Gaps = 31/250 (12%)
Query: 390 SGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPA-DPDT 448
+ SP PP SP+ T P + + + S+ + T S +P P T
Sbjct: 427 TASPTRTPPRASPT-----GTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPST 481
Query: 449 AIVHPVPIRM----TPSKIHMQEME----LKRTGSDHTNPTSPLLVKPSDLLEENKINSS 500
A P R TPS+ + +ME + RT S + +P P+ + S
Sbjct: 482 ASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTG-------SPS 534
Query: 501 VKFASGN----TVDGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSH 556
A G+ + S S T P + S T R+ +P PP P+
Sbjct: 535 TALAMGSPSRAALTRTPSRASLTRTPSR-ASLTTPSRASLTRTPSTVLLTRMPPSASPTG 593
Query: 557 --SRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPR---PQPSQAPGPAVHRPVDADGLIT 611
SR+S M + +T A + PP P P+ S P P +
Sbjct: 594 MPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASPTGTPPRAS 653
Query: 612 HTSTSPQQIP 621
T T P+ P
Sbjct: 654 PTGTPPRASP 663
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 45.1 bits (105), Expect = 3e-04
Identities = 99/506 (19%), Positives = 173/506 (34%), Gaps = 60/506 (11%)
Query: 290 VNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHL 349
VN K + +N + S+A + + S+ L+LS WE S D+ TL +
Sbjct: 256 VNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLS-AWESSIVDRLMTPTLSFLARSRSA 314
Query: 350 VVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAP--PSKSPSMP-S 406
V +NG D P S G QP S + P S SP P S
Sbjct: 315 VTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCS 374
Query: 407 LNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQ 466
+ ++ + E+ E + S P P+R P +Q
Sbjct: 375 VTRSVHRCAPAGERGERRKPNAGGS---------------------PAPVRRRPEASPVQ 413
Query: 467 EMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDPEQIG 526
+ E K ++ S L + S ++ S S +T S + P
Sbjct: 414 KKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSK--ARPSSPS 471
Query: 527 SNVTRQRSHSGT-SPDNTAPPPPP-PR---------------PQPSHSRSSSLDMNRTFT 569
++ R S + P +T PP PP PR + S S + D +++
Sbjct: 472 TSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKR 531
Query: 570 VTTGQQQAGVVAHP---PAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNF 626
+ ++++ A P PA P P P Q P P DA L + + +P P +P
Sbjct: 532 RASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKP-- 589
Query: 627 ADFSQFEVFAASNVNDEQDDE--AEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASA 684
A + E+ AEK + + + L+ + EE+ A A
Sbjct: 590 ---------MAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREA 640
Query: 685 PANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDK 744
A + + R + ++E E + + + ++ + A + + R +
Sbjct: 641 EARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQ 700
Query: 745 KAIQASIRRNKETNTVLARLNSELQQ 770
+ + RR + + SE+ +
Sbjct: 701 QEQERQERRKRLEEIMKRTRKSEVSE 726
Score = 35.0 bits (79), Expect = 0.27
Identities = 47/222 (21%), Positives = 73/222 (32%), Gaps = 17/222 (7%)
Query: 536 SGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQA 595
+G P A PP PRP P S A V PP PP + + +
Sbjct: 11 AGAPPAVVARTPPEPRPSPEGDPSP----------PPPPMSALVPDTPPDTPPAMKNATS 60
Query: 596 PGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVL 655
P G + PQ+ E P+ S+ A D + P
Sbjct: 61 SKQLPLEPESPSGQVGPRPAPPQE--ESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPT 118
Query: 656 PAEKASDPASSLRVAKTDSK---TEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDEL 712
+ P + V K + +E+ A +K L K R K E
Sbjct: 119 AVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQER 178
Query: 713 RPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRN 754
R ++E K A L + + + K+K+ +A+I+R+
Sbjct: 179 RRRLEEQRLKAEQRRAALEERQR--QKLEKNKERYEAAIQRS 218
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,162,725
Number of Sequences: 37866
Number of extensions: 2184953
Number of successful extensions: 22219
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 945
Number of HSP's that attempted gapping in prelim test: 15544
Number of HSP's gapped (non-prelim): 5890
length of query: 795
length of database: 18,247,518
effective HSP length: 110
effective length of query: 685
effective length of database: 14,082,258
effective search space: 9646346730
effective search space used: 9646346730
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.