Guide to the Human Genome
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Search of human proteins with 190358543

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190358543 hypothetical protein LOC57654 [Homo sapiens]
         (709 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190358543 hypothetical protein LOC57654 [Homo sapiens]            1435   0.0  
gi|239748340 PREDICTED: hypothetical protein XP_002346633 [Homo ...   546   e-155
gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa...    41   0.003
gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s...    41   0.003
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              40   0.010
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         39   0.022
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         39   0.022
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         39   0.022
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         39   0.022
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         39   0.022
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         39   0.022
gi|33350928 disabled homolog 1 [Homo sapiens]                          39   0.022
gi|23110966 light ear protein isoform a [Homo sapiens]                 37   0.048
gi|23110970 light ear protein isoform b [Homo sapiens]                 37   0.048
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    37   0.082
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    37   0.082
gi|38044112 restin isoform b [Homo sapiens]                            37   0.082
gi|4506751 restin isoform a [Homo sapiens]                             37   0.082
gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II, pol...    36   0.11 
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    36   0.11 
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    36   0.14 
gi|194097365 FtsJ homolog 3 [Homo sapiens]                             36   0.14 
gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo ...    35   0.18 
gi|166706887 syncoilin, intermediate filament 1 isoform 1 [Homo ...    35   0.18 
gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s...    35   0.18 
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo...    35   0.18 
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo...    35   0.18 
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    35   0.24 
gi|195963410 MEF2 activating motif and SAP domain containing tra...    35   0.24 
gi|32698970 MEF2 activating motif and SAP domain containing tran...    35   0.24 

>gi|190358543 hypothetical protein LOC57654 [Homo sapiens]
          Length = 709

 Score = 1435 bits (3714), Expect = 0.0
 Identities = 709/709 (100%), Positives = 709/709 (100%)

Query: 1   MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
           MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS
Sbjct: 1   MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60

Query: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
           AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW
Sbjct: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120

Query: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180
           NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER
Sbjct: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180

Query: 181 EMQEMSGEIESCLTEVESCFRLLVPFDFDPNPETESLGMASGMSDALRSSCAGQVGPCRS 240
           EMQEMSGEIESCLTEVESCFRLLVPFDFDPNPETESLGMASGMSDALRSSCAGQVGPCRS
Sbjct: 181 EMQEMSGEIESCLTEVESCFRLLVPFDFDPNPETESLGMASGMSDALRSSCAGQVGPCRS 240

Query: 241 GTPDPRDGEQPCCSRDLPASAGHPRAGGGAQPSQTATGDPSDEDEDSDLEEFVRSHGLGS 300
           GTPDPRDGEQPCCSRDLPASAGHPRAGGGAQPSQTATGDPSDEDEDSDLEEFVRSHGLGS
Sbjct: 241 GTPDPRDGEQPCCSRDLPASAGHPRAGGGAQPSQTATGDPSDEDEDSDLEEFVRSHGLGS 300

Query: 301 HKYTLDVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQRFTRVGTHGGC 360
           HKYTLDVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQRFTRVGTHGGC
Sbjct: 301 HKYTLDVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQRFTRVGTHGGC 360

Query: 361 LKRAIDLKAELELVLRKYKELDIEPEGGERRRTEALGDAEEDEDDEDFVEVPEKEGYEPH 420
           LKRAIDLKAELELVLRKYKELDIEPEGGERRRTEALGDAEEDEDDEDFVEVPEKEGYEPH
Sbjct: 361 LKRAIDLKAELELVLRKYKELDIEPEGGERRRTEALGDAEEDEDDEDFVEVPEKEGYEPH 420

Query: 421 IPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPS 480
           IPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPS
Sbjct: 421 IPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPS 480

Query: 481 RALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEV 540
           RALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEV
Sbjct: 481 RALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEV 540

Query: 541 VNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGKIVPRDDEGRP 600
           VNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGKIVPRDDEGRP
Sbjct: 541 VNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGKIVPRDDEGRP 600

Query: 601 LDPEDRAREQRRQLQKQERPEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 660
           LDPEDRAREQRRQLQKQERPEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN
Sbjct: 601 LDPEDRAREQRRQLQKQERPEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 660

Query: 661 LKAQADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN 709
           LKAQADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN
Sbjct: 661 LKAQADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN 709


>gi|239748340 PREDICTED: hypothetical protein XP_002346633 [Homo
           sapiens]
          Length = 465

 Score =  546 bits (1406), Expect = e-155
 Identities = 303/439 (69%), Positives = 318/439 (72%), Gaps = 59/439 (13%)

Query: 290 EEFVRSHGLGSHKYTLDVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQ 349
           E FVRSH        L V    E L++    D    +   R+  + +R     AV  W +
Sbjct: 67  ELFVRSHQFRM----LVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122

Query: 350 RFTR------VGTHGGCLKRAIDLK-------AELELVLRKYKELD------IEPEGGER 390
           +F        +G H     + +D +       AE +    K K LD            E 
Sbjct: 123 KFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREM 182

Query: 391 RRTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM 450
           ++TEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM
Sbjct: 183 QQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM 242

Query: 451 DEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 510
           DEEVSDPTSAAAQLRQL   L  PSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY
Sbjct: 243 DEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302

Query: 511 WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP 570
           WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP
Sbjct: 303 WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP 362

Query: 571 RPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAREQRRQLQKQERPEWQDPELMRD 630
           RPDGRLCERQDRLK                                    EWQDPELMRD
Sbjct: 363 RPDGRLCERQDRLK------------------------------------EWQDPELMRD 386

Query: 631 VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN 690
           VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN
Sbjct: 387 VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN 446

Query: 691 RMDQKKHEKFSNQFNYALN 709
           RMDQKKHEKFSNQFNYALN
Sbjct: 447 RMDQKKHEKFSNQFNYALN 465



 Score =  362 bits (928), Expect = e-100
 Identities = 183/184 (99%), Positives = 184/184 (100%)

Query: 1   MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
           MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS
Sbjct: 1   MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60

Query: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
           AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW
Sbjct: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120

Query: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180
           NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER
Sbjct: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180

Query: 181 EMQE 184
           EMQ+
Sbjct: 181 EMQQ 184


>gi|41406057 amyloid beta A4 protein isoform c precursor [Homo
           sapiens]
          Length = 695

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 16/147 (10%)

Query: 398 DAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRT--RMDEEVS 455
           +A++DEDDED  EV E+E  EP+           E A E+ T +    T T   ++E V 
Sbjct: 241 EADDDEDDEDGDEV-EEEAEEPY-----------EEATERTTSIATTTTTTTESVEEVVR 288

Query: 456 DPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQEL 515
            PT+AA+    +  +L  P   +      + +E  +       + V+    +     + L
Sbjct: 289 VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 348

Query: 516 PTAGKIVKSDSQHRFWKPSEVEEEVVN 542
           P A K  K+  QH   K   +E+E  N
Sbjct: 349 PKADK--KAVIQHFQEKVESLEQEAAN 373


>gi|209915570 amyloid beta A4 protein isoform e precursor [Homo
           sapiens]
          Length = 639

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 16/147 (10%)

Query: 398 DAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRT--RMDEEVS 455
           +A++DEDDED  EV E+E  EP+           E A E+ T +    T T   ++E V 
Sbjct: 185 EADDDEDDEDGDEV-EEEAEEPY-----------EEATERTTSIATTTTTTTESVEEVVR 232

Query: 456 DPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQEL 515
            PT+AA+    +  +L  P   +      + +E  +       + V+    +     + L
Sbjct: 233 VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 292

Query: 516 PTAGKIVKSDSQHRFWKPSEVEEEVVN 542
           P A K  K+  QH   K   +E+E  N
Sbjct: 293 PKADK--KAVIQHFQEKVESLEQEAAN 317


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 57/277 (20%), Positives = 104/277 (37%), Gaps = 32/277 (11%)

Query: 380  ELDIEPEGGERRRTEALGDAEEDEDDEDFVEVPEKE-GYEPHIPDHLRPEYGLEAAPEKD 438
            E + +PE  +    EA G+A+ + +D   VE PE E   +P       PE   EA PE +
Sbjct: 1864 EGEAQPESEDVEAPEAEGEAQPESED---VETPEAEWEVQPESEGAEAPEAEKEAQPETE 1920

Query: 439  TVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQKLAAERAR 498
            + V  L T     E   +P S  A+ ++  +      +A  +    +P E++ + ++ A 
Sbjct: 1921 S-VEALET-----EGEDEPESEGAEAQEAEE------AAQEAEGQTQP-ESEVIESQEAE 1967

Query: 499  APVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAG 558
                P   D+     E+ T     ++  +    +  E E E+  A+      S  +    
Sbjct: 1968 EEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVE--- 2024

Query: 559  KFEPVQHWCRAPRPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAREQRRQLQKQE 618
                       P+ +G   +  +       G   P  D     + E+ A+E   ++Q+ E
Sbjct: 2025 ---------AQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAE 2075

Query: 619  ---RPEWQDPELMRDVEAATGQDLGSSRYSGKGRGKK 652
                PE +D +       A  +  G      +G  +K
Sbjct: 2076 GEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQK 2112



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 56/260 (21%), Positives = 95/260 (36%), Gaps = 44/260 (16%)

Query: 394  EALGDAEEDEDDEDFVEVPEKEG--------YEPHIPDHLRPEYGLEAAPEKDTVVRCLR 445
            EA G+A+ + +    VE PE EG         +P   D   PE   EA PE + V     
Sbjct: 1839 EAEGEAQPESEG---VEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDV----- 1890

Query: 446  TRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYG 505
              T   E    P S  A+  +      P + +  +       E +   AE   A      
Sbjct: 1891 -ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQE 1949

Query: 506  VDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQH 565
             +    GQ  P + ++++S       +P   + E +  ++            G+ +P   
Sbjct: 1950 AE----GQTQPES-EVIESQEAEEEAQPESEDVEALEVEVETQ------EAEGEAQPESE 1998

Query: 566  WCRAPRPDGRLCERQDRLKCPFHGKIVPRDD--EGRPLDPEDRAREQRRQLQKQE---RP 620
               AP  +G + E ++  +        P  D  E +P    + A+E   + QK E   +P
Sbjct: 1999 DVEAPEAEGEMQEAEEEAQ--------PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050

Query: 621  E---WQDPELMRDVEAATGQ 637
            E    + PE   + + A G+
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGE 2070



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 54/275 (19%), Positives = 95/275 (34%), Gaps = 51/275 (18%)

Query: 389  ERRRTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGL--------EAAPEKDTV 440
            E    EAL    EDE + +  E  E E          +PE  +        EA PE + V
Sbjct: 1918 ETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDV 1977

Query: 441  VRC-LRTRTRMDEEVSDPTS-------AAAQLRQLRDHLPPPSSASPSRALPEPQEAQKL 492
                +   T+  E  + P S       A  ++++  +   P S    ++   E +EAQ++
Sbjct: 1978 EALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEV 2037

Query: 493  AAERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSR 552
              E  +             G   P +  +   +++    +  E E EV  A+      S 
Sbjct: 2038 EGETQKTE-----------GDAQPESDGVEAPEAEE---EAQEAEGEVQEAEGEAHPESE 2083

Query: 553  HI---TFAGKFEPVQHWCRAPRPDGRLCERQDRLKCP-----------------FHGKIV 592
             +      G+ +P      AP  +G   ++ + ++ P                   G+  
Sbjct: 2084 DVDAQEAEGEAQPESEGVEAPEAEGE-AQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQ 2142

Query: 593  PRDDEGRPLDPEDRAREQRRQLQKQERPEWQDPEL 627
            P  +     D E  A+ +   ++ QE  E   PEL
Sbjct: 2143 PESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPEL 2177



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 100/505 (19%), Positives = 164/505 (32%), Gaps = 125/505 (24%)

Query: 3    QKLSKLVEELTTSGE--PRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
            Q  ++ VE L T GE  P     + +E ++  + +E Q      ++ +Q  +E A+    
Sbjct: 1916 QPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPE-- 1973

Query: 61   AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
                                S   E LE+ + T  A+      EA            EG 
Sbjct: 1974 --------------------SEDVEALEVEVETQEAEG-----EAQPESEDVEAPEAEGE 2008

Query: 121  NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180
             ++  E  +  + G      ++  + Q+    +   +K E + Q   D +    A +AE 
Sbjct: 2009 MQEAEEEAQPESDGVEAQPKSEGEEAQEVEGET---QKTEGDAQPESDGV---EAPEAEE 2062

Query: 181  EMQEMSGEIESCLTEVESCFRLLVPFDFDPNPETESLGMASGMSDALRSSCAGQVGPCRS 240
            E QE  GE++                + + +PE+E +       +A   S  G   P   
Sbjct: 2063 EAQEAEGEVQEA--------------EGEAHPESEDVDAQEAEGEAQPES-EGVEAPEAE 2107

Query: 241  GTPDPRDGEQPCCSRDLPASAGHPRAGGGAQPSQTATGDPSDEDEDSDLEEFVRSHGLGS 300
            G     +G +             P   G AQP       P  E E         S G+ +
Sbjct: 2108 GEAQKAEGIEA------------PETEGEAQPESEGIEAPEAEGEAQP-----ESEGVEA 2150

Query: 301  HKYTLDVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQRFTRVGTHGGC 360
                 + +  SEG++ QE E+                                       
Sbjct: 2151 QDAEGEAQPESEGIEAQEAEE--------------------------------------- 2171

Query: 361  LKRAIDLKAELELVLRKYKELDIEPEGGERRRTEALGDAEEDEDDEDFVEV-----PEKE 415
                 + + ELE V     E + +PE       EA G+A+ + +  +  E      PE E
Sbjct: 2172 -----EAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPE 2226

Query: 416  GYE-PHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPP 474
            G E P      +PE   E   EK    + +       EE S+ +S   + R      PPP
Sbjct: 2227 GVETPEAEGEAQPESEGETQGEKKGSPQ-VSLGDGQSEEASESSSPVPEDRP----TPPP 2281

Query: 475  SSASPSRALPEPQEAQKLAAERARA 499
               SP    P  +   +     +RA
Sbjct: 2282 ---SPGGDTPHQRPGSQTGPSSSRA 2303


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 15/200 (7%)

Query: 2   DQKLSKLVEELTTS-GEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
           +++++ L ++L  +  E   N EK++EL+      E+ + R    +I    +E+ E++ S
Sbjct: 532 EEEINVLKQDLQNALEESERNKEKVRELE------EKLVEREKGTVIKPPVEEYEEMKSS 585

Query: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
              ++E +  +   F        QE +     T  +Q      + A+ +++A  R ++  
Sbjct: 586 YCSVIENMN-KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDEL 644

Query: 121 NEKFGEA---YKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQ 177
           N++  E    YK+        R  K ++  D  A  +   K E EK   L  + + +A  
Sbjct: 645 NKQVSELSQLYKEAQAELEDYRKRKSLE--DVTAEYI--HKAEHEKLMQLTNVSRAKAED 700

Query: 178 AEREMQEMSGEIESCLTEVE 197
           A  EM+    ++ + LT+++
Sbjct: 701 ALSEMKSQYSKVLNELTQLK 720


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 15/200 (7%)

Query: 2   DQKLSKLVEELTTS-GEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
           +++++ L ++L  +  E   N EK++EL+      E+ + R    +I    +E+ E++ S
Sbjct: 521 EEEINVLKQDLQNALEESERNKEKVRELE------EKLVEREKGTVIKPPVEEYEEMKSS 574

Query: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
              ++E +  +   F        QE +     T  +Q      + A+ +++A  R ++  
Sbjct: 575 YCSVIENMN-KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDEL 633

Query: 121 NEKFGEA---YKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQ 177
           N++  E    YK+        R  K ++  D  A  +   K E EK   L  + + +A  
Sbjct: 634 NKQVSELSQLYKEAQAELEDYRKRKSLE--DVTAEYI--HKAEHEKLMQLTNVSRAKAED 689

Query: 178 AEREMQEMSGEIESCLTEVE 197
           A  EM+    ++ + LT+++
Sbjct: 690 ALSEMKSQYSKVLNELTQLK 709


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 15/200 (7%)

Query: 2   DQKLSKLVEELTTS-GEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
           +++++ L ++L  +  E   N EK++EL+      E+ + R    +I    +E+ E++ S
Sbjct: 500 EEEINVLKQDLQNALEESERNKEKVRELE------EKLVEREKGTVIKPPVEEYEEMKSS 553

Query: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
              ++E +  +   F        QE +     T  +Q      + A+ +++A  R ++  
Sbjct: 554 YCSVIENMN-KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDEL 612

Query: 121 NEKFGEA---YKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQ 177
           N++  E    YK+        R  K ++  D  A  +   K E EK   L  + + +A  
Sbjct: 613 NKQVSELSQLYKEAQAELEDYRKRKSLE--DVTAEYI--HKAEHEKLMQLTNVSRAKAED 668

Query: 178 AEREMQEMSGEIESCLTEVE 197
           A  EM+    ++ + LT+++
Sbjct: 669 ALSEMKSQYSKVLNELTQLK 688


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 15/200 (7%)

Query: 2   DQKLSKLVEELTTS-GEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
           +++++ L ++L  +  E   N EK++EL+      E+ + R    +I    +E+ E++ S
Sbjct: 529 EEEINVLKQDLQNALEESERNKEKVRELE------EKLVEREKGTVIKPPVEEYEEMKSS 582

Query: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
              ++E +  +   F        QE +     T  +Q      + A+ +++A  R ++  
Sbjct: 583 YCSVIENMN-KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDEL 641

Query: 121 NEKFGEA---YKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQ 177
           N++  E    YK+        R  K ++  D  A  +   K E EK   L  + + +A  
Sbjct: 642 NKQVSELSQLYKEAQAELEDYRKRKSLE--DVTAEYI--HKAEHEKLMQLTNVSRAKAED 697

Query: 178 AEREMQEMSGEIESCLTEVE 197
           A  EM+    ++ + LT+++
Sbjct: 698 ALSEMKSQYSKVLNELTQLK 717


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 15/200 (7%)

Query: 2   DQKLSKLVEELTTS-GEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
           +++++ L ++L  +  E   N EK++EL+      E+ + R    +I    +E+ E++ S
Sbjct: 529 EEEINVLKQDLQNALEESERNKEKVRELE------EKLVEREKGTVIKPPVEEYEEMKSS 582

Query: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
              ++E +  +   F        QE +     T  +Q      + A+ +++A  R ++  
Sbjct: 583 YCSVIENMN-KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDEL 641

Query: 121 NEKFGEA---YKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQ 177
           N++  E    YK+        R  K ++  D  A  +   K E EK   L  + + +A  
Sbjct: 642 NKQVSELSQLYKEAQAELEDYRKRKSLE--DVTAEYI--HKAEHEKLMQLTNVSRAKAED 697

Query: 178 AEREMQEMSGEIESCLTEVE 197
           A  EM+    ++ + LT+++
Sbjct: 698 ALSEMKSQYSKVLNELTQLK 717


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 15/200 (7%)

Query: 2   DQKLSKLVEELTTS-GEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
           +++++ L ++L  +  E   N EK++EL+      E+ + R    +I    +E+ E++ S
Sbjct: 529 EEEINVLKQDLQNALEESERNKEKVRELE------EKLVEREKGTVIKPPVEEYEEMKSS 582

Query: 61  AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
              ++E +  +   F        QE +     T  +Q      + A+ +++A  R ++  
Sbjct: 583 YCSVIENMN-KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDEL 641

Query: 121 NEKFGEA---YKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQ 177
           N++  E    YK+        R  K ++  D  A  +   K E EK   L  + + +A  
Sbjct: 642 NKQVSELSQLYKEAQAELEDYRKRKSLE--DVTAEYI--HKAEHEKLMQLTNVSRAKAED 697

Query: 178 AEREMQEMSGEIESCLTEVE 197
           A  EM+    ++ + LT+++
Sbjct: 698 ALSEMKSQYSKVLNELTQLK 717


>gi|33350928 disabled homolog 1 [Homo sapiens]
          Length = 555

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 57/254 (22%), Positives = 95/254 (37%), Gaps = 26/254 (10%)

Query: 269 GAQPSQTATGDPSDEDEDSDLEEFVR-SHGLGSHKYTLDVELCSEGLKVQENEDNLALIH 327
           G      A GD   +D    L+  V  +   G HK  + + +   G+K+ + +      H
Sbjct: 48  GIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGALQHH 107

Query: 328 AARDTLKLIR-----NKFLPAVCS--WIQRFTRVGTHGGCLKRAIDLKAELELVLRKYKE 380
            A   +  I      ++    VC      RF  + T        +DL+   +L+    + 
Sbjct: 108 HAVHEISYIAKDITDHRAFGYVCGKEGNHRFVAIKTAQAAEPVILDLRDLFQLIYELKQR 167

Query: 381 LDIEPEGGERRRTEAL---GDAEEDEDDEDFVEVPEKEGYEP-HIPDHLRPEYGLEAAPE 436
            ++E +  + ++ E        EED +D  +  +  + G+EP   P+     Y +  + +
Sbjct: 168 EELEKKAQKDKQCEQAVYQTILEEDVEDPVYQYIVFEAGHEPIRDPETEENIYQVPTSQK 227

Query: 437 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSAS-PSRALPE----PQEAQK 491
           K+ V          D   S P SA  QL    D   PP   S P+ A P     P  +Q 
Sbjct: 228 KEGVY---------DVPKSQPVSAVTQLELFGDMSTPPDITSPPTPATPGDAFIPSSSQT 278

Query: 492 LAAERARAPVVPYG 505
           L A       VP+G
Sbjct: 279 LPASADVFSSVPFG 292


>gi|23110966 light ear protein isoform a [Homo sapiens]
          Length = 708

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 13/118 (11%)

Query: 408 FVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQL 467
           F+ VP  +G  P+    L     LE  P +DT +  LR  +  +      T   AQ  QL
Sbjct: 389 FLHVPVPDGRAPYCKASLSASSSLEPTPPEDTAISSLRPPSAPEM----LTQHGAQ-EQL 443

Query: 468 RDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSD 525
            DH    S A   RA P P+        R R P++   +D    G +LPT  + +  D
Sbjct: 444 EDHPGHSSQAPIPRADPLPR--------RTRRPLLLPRLDPGQRGNKLPTGEQGLDED 493


>gi|23110970 light ear protein isoform b [Homo sapiens]
          Length = 703

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 13/118 (11%)

Query: 408 FVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQL 467
           F+ VP  +G  P+    L     LE  P +DT +  LR  +  +      T   AQ  QL
Sbjct: 384 FLHVPVPDGRAPYCKASLSASSSLEPTPPEDTAISSLRPPSAPEM----LTQHGAQ-EQL 438

Query: 468 RDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSD 525
            DH    S A   RA P P+        R R P++   +D    G +LPT  + +  D
Sbjct: 439 EDHPGHSSQAPIPRADPLPR--------RTRRPLLLPRLDPGQRGNKLPTGEQGLDED 488


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 36.6 bits (83), Expect = 0.082
 Identities = 24/117 (20%), Positives = 54/117 (46%), Gaps = 12/117 (10%)

Query: 525 DSQHRFWKPSEV---------EEEVVNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGR 575
           + + + W+  E          E+E    +  EM++ +      + E +Q   +  R + +
Sbjct: 513 EQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572

Query: 576 LCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAREQRRQLQKQERPEWQDPELMRDVE 632
           + E++++++     K   R+ E +  + E++ REQ   +Q+QE   W+  E M + E
Sbjct: 573 IREQEEKIR---EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 626



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 8/95 (8%)

Query: 103 REAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEE 162
           RE  +++R+      E   EK GE  +K+       R  +K+  Q+   R   E+ RE+E
Sbjct: 533 REQEEKIREQEEMMQEQ-EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE 591

Query: 163 KQKHLDKIYQERASQAEREMQEMSGEIESCLTEVE 197
                +KI+++   +  RE +EM  E E  + E E
Sbjct: 592 -----EKIWEQ--EEKIREQEEMMQEQEEKMWEQE 619



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 38/202 (18%), Positives = 78/202 (38%), Gaps = 44/202 (21%)

Query: 432 EAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQK 491
           E   E+D +   L   T  DEE+ +  +      +L++ L    S      L   +  +K
Sbjct: 197 ELTKERDALSLELYRNTITDEELKEKNA------KLQEKLQLVESEKSEIQLNVKELKRK 250

Query: 492 LAAERARAPVVPYGVDLHYWGQELPT-AGKIVKSDSQHRFWKPSEVEEEVVNADISEMLR 550
           L   +   P      +  + G+EL + + K+     ++  W     ++E       +M R
Sbjct: 251 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE------EKMWR 304

Query: 551 SRHITFAGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAREQ 610
                     E +Q W      + ++ E++++++                 + E++ REQ
Sbjct: 305 QE--------EKIQEW------EEKIQEQEEKIR-----------------EQEEKIREQ 333

Query: 611 RRQLQKQERPEWQDPELMRDVE 632
             ++++QE   W+  E MR  E
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQE 355


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 36.6 bits (83), Expect = 0.082
 Identities = 112/510 (21%), Positives = 178/510 (34%), Gaps = 70/510 (13%)

Query: 8   LVEELT--TSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIV 65
           L++E T  TSGE   N EK     K  K++  Q  R  R+  +   + ++E  ++  Q  
Sbjct: 545 LLKEKTDDTSGED--NDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ-- 600

Query: 66  EELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFG 125
                 S +   + ++    + E  + T     L   R  +   R   ++ V      + 
Sbjct: 601 ------SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYF 654

Query: 126 EAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQEM 185
              K+  L     +H  K++ ++ NAR    +K++       +  +       E E   +
Sbjct: 655 NYKKRQNLDEILQQHKLKME-KERNAR---RKKKKAPAAASEEAAFPPVVEDEEMEASGV 710

Query: 186 SGEIESCLTEVESCFRLLVPFDFDPNPETESLGMASGMSDALRSSCAGQVGPCRSGTPDP 245
           SG  E  + E E+        +  P+P TE+    +G +     +  G  GP   G P P
Sbjct: 711 SGNEEEMVEEAEATVNNSSDTESIPSPHTEA-AKDTGQNGPKPPATLGADGP-PPGPPTP 768

Query: 246 RDGEQPCCSRDLPASAGHPRAGGGAQPSQTATGDPSDEDEDSDLEEFVRSHGLGSHKYTL 305
              + P  +   PAS        GA     A   PS        EE              
Sbjct: 769 PPEDIPAPTEPTPAS-----EATGAPTPPPAPPSPSAPPPVVPKEE-------------- 809

Query: 306 DVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQRFTRVGTHGGCLKRAI 365
             E  +    V+E E+       A + L +   K    V S        G   G    A 
Sbjct: 810 KEEETAAAPPVEEGEEQKP---PAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAA 866

Query: 366 DLKAELELVLRKYKELDIEPEGGERRRTEALGDAEEDEDDEDFV----EVPEKEGYEPH- 420
           +  AE  L   K        EGG  R T A       + D        EV E EG + + 
Sbjct: 867 EATAEGALKAEK-------KEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNR 919

Query: 421 ----IPDHLRP--EYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPP 474
                P  L P  +    A+P+K   ++ L+ R           +A   ++  + H PP 
Sbjct: 920 LLSPRPSLLTPTGDPRANASPQKPLDLKQLKQR----------AAAIPPIQVTKVHEPPR 969

Query: 475 SSASPSR-ALPEPQEAQKLAAERARAPVVP 503
             A+P++ A P P   Q L  E + AP  P
Sbjct: 970 EDAAPTKPAPPAPPPPQNLQPE-SDAPQQP 998



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 63/289 (21%), Positives = 120/289 (41%), Gaps = 48/289 (16%)

Query: 368 KAELELVLRKYKELDIEPEGGERRRTE-ALGDAEEDED-DEDFVEVPEKEGYEPHIPDHL 425
           K+E+E +  K   L++ P+   R     A G     ED  +D     + E   P  P H 
Sbjct: 97  KSEMEFIESKRPRLELLPDPLLRPSPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHT 156

Query: 426 RPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPE 485
            PE  LE  P + +    ++   R+D E++      ++L++ +  L    +A P    PE
Sbjct: 157 DPE--LELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEE-EAAKP----PE 209

Query: 486 PQEAQKLAAERARAPVVPYGVDL-HYWGQELPTAGKIVKSDSQHR-------------FW 531
           P++           PV P  ++  H    ++       K+++ HR             + 
Sbjct: 210 PEK-----------PVSPPPIESKHRSLVQIIYDENRKKAEAAHRILEGLGPQVELPLYN 258

Query: 532 KPSEVEEEVVNADISEMLRSRHIT-FAGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGK 590
           +PS+  +   N  I++ +R + I  F  +    + W      + + C+R D+L   +  K
Sbjct: 259 QPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQW------EQKFCQRYDQLMEAWEKK 312

Query: 591 IVPRDDEGRPLDPEDRAREQR-RQLQKQERPE-WQDPELMRDVEAATGQ 637
           +     E    +P  RA+E + R+  +++ PE  +  EL   +++  GQ
Sbjct: 313 V-----ERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQ 356


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 36.6 bits (83), Expect = 0.082
 Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 31/213 (14%)

Query: 6   SKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLL----IAQLTQEHAEIRLSA 61
           +K+++  T+  + +   EK+ +L  + K+S E  S   +L      A+   +H EI  +A
Sbjct: 710 TKVIDNFTS--QLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNA 767

Query: 62  FQIVEELFVRSHQFRMLVVSNFQEFL------------ELTLGTDPAQPLPPPREAAQRL 109
                    R  Q R L ++N QE L            EL +  +          + QR 
Sbjct: 768 ESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRS 827

Query: 110 RQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDK 169
            Q T   +    E+F      L+     LR N      D  A+   + +REE+  K  +K
Sbjct: 828 MQETVNKLHQKEEQFN----MLSSDLEKLREN----LADMEAKFREKDEREEQLIKAKEK 879

Query: 170 IYQERASQAEREMQEMSGEIESCLTEVESCFRL 202
           +  + A     E+ +MSG+  S LT++    RL
Sbjct: 880 LENDIA-----EIMKMSGDNSSQLTKMNDELRL 907


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 36.6 bits (83), Expect = 0.082
 Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 31/213 (14%)

Query: 6   SKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLL----IAQLTQEHAEIRLSA 61
           +K+++  T+  + +   EK+ +L  + K+S E  S   +L      A+   +H EI  +A
Sbjct: 745 TKVIDNFTS--QLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNA 802

Query: 62  FQIVEELFVRSHQFRMLVVSNFQEFL------------ELTLGTDPAQPLPPPREAAQRL 109
                    R  Q R L ++N QE L            EL +  +          + QR 
Sbjct: 803 ESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRS 862

Query: 110 RQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDK 169
            Q T   +    E+F      L+     LR N      D  A+   + +REE+  K  +K
Sbjct: 863 MQETVNKLHQKEEQFN----MLSSDLEKLREN----LADMEAKFREKDEREEQLIKAKEK 914

Query: 170 IYQERASQAEREMQEMSGEIESCLTEVESCFRL 202
           +  + A     E+ +MSG+  S LT++    RL
Sbjct: 915 LENDIA-----EIMKMSGDNSSQLTKMNDELRL 942


>gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1b
           [Homo sapiens]
          Length = 867

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 40/122 (32%), Positives = 51/122 (41%), Gaps = 19/122 (15%)

Query: 209 DPNPETESLGM--ASGMSDALR----SSCAGQVGPCRSGTPDPRD----GEQPCCSRDL- 257
           DP   T++ G+  ++G+    R    S  A      R G PD RD     + P  S++L 
Sbjct: 361 DPEGVTQAPGVEPSNGLEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQAPTSSQELA 420

Query: 258 --PASAGHPRAGG----GAQPSQTATGDPSDEDEDSDLEEFVRSHGLGSHKYTLDVELCS 311
             P   G    GG    G +P+Q ATG   D D  SD E    S G  S     D E  S
Sbjct: 421 GAPEPQGSCAQGGRVAPGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGE--S 478

Query: 312 EG 313
           EG
Sbjct: 479 EG 480


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 40/122 (32%), Positives = 51/122 (41%), Gaps = 19/122 (15%)

Query: 209 DPNPETESLGM--ASGMSDALR----SSCAGQVGPCRSGTPDPRD----GEQPCCSRDL- 257
           DP   T++ G+  ++G+    R    S  A      R G PD RD     + P  S++L 
Sbjct: 361 DPEGVTQAPGVEPSNGLEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQAPTSSQELA 420

Query: 258 --PASAGHPRAGG----GAQPSQTATGDPSDEDEDSDLEEFVRSHGLGSHKYTLDVELCS 311
             P   G    GG    G +P+Q ATG   D D  SD E    S G  S     D E  S
Sbjct: 421 GAPEPQGSCAQGGRVAPGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGE--S 478

Query: 312 EG 313
           EG
Sbjct: 479 EG 480


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 48/264 (18%), Positives = 94/264 (35%), Gaps = 15/264 (5%)

Query: 384 EPEGGERRRTEALGDAEE--DEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVV 441
           E E   R   E + + EE   + +E+  E  EKE  +  +P+     +  E   E++  +
Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455

Query: 442 RCLRTRTRMDEEVSDPTSAA---AQLRQLRDHL--PPPSSASPSRALPEPQEAQKLAAER 496
                + R  EE+           ++R+  D +           + + + +E      ER
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515

Query: 497 ARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEV--------EEEVVNADISEM 548
            R            W QE     +    + + + W   E         E E    +  EM
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575

Query: 549 LRSRHITFAGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAR 608
           +R +      + E ++             + Q+        K+  +++E +  + E+   
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW 635

Query: 609 EQRRQLQKQERPEWQDPELMRDVE 632
           EQ  ++Q+QE   W+  E MR+ E
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQE 659



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 11/62 (17%)

Query: 571 RPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAREQRRQLQKQERPEWQDPELMRD 630
           R + RL E++  L+           ++ + L  + + REQ  Q+Q+QE   W+  E MR+
Sbjct: 280 RQEKRLREQEKELR-----------EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328

Query: 631 VE 632
            E
Sbjct: 329 QE 330



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 21/105 (20%), Positives = 48/105 (45%), Gaps = 1/105 (0%)

Query: 595 DDEGRPLDPEDRAREQRRQLQKQERPEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRR 654
           D E R  + ++R RE+  ++++Q++  WQ  E MR+ +    Q+  +     K R ++R 
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKM-WQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562

Query: 655 YPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEK 699
                 ++ + +  R +  +    +  +R     M   ++K  E+
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607


>gi|194097365 FtsJ homolog 3 [Homo sapiens]
          Length = 847

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 14/113 (12%)

Query: 594 RDDEGRPLDP--EDRAREQRRQLQKQERPEWQDPELMRDVEAATGQDLGSSR--YSGKGR 649
           R+   RP+    E +AR++RR L++ E+   +   ++  V+ +  + +   R  Y   G 
Sbjct: 732 REINARPIKKVAEAKARKKRRMLKRLEQTRKKAEAVVNTVDISEREKVAQLRSLYKKAGL 791

Query: 650 GKKRRYPSLTNLKAQADTARARIGRKVFAKAAVR---RVVAAMNRMDQKKHEK 699
           GK++R+ +          A+  +GRKV   A VR   +VV +  + DQ+  ++
Sbjct: 792 GKEKRHVTYV-------VAKKGVGRKVRRPAGVRGHFKVVDSRMKKDQRAQQR 837


>gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo
           sapiens]
          Length = 476

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/201 (22%), Positives = 94/201 (46%), Gaps = 31/201 (15%)

Query: 1   MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLI-AQLTQE--HAEI 57
           ++++  +L+ EL    EP L     +E++++     + +  AY+L   A+L ++    EI
Sbjct: 189 LEEERDQLIHELVLLREPAL-----QEVQQV----HQDILAAYKLHAQAELERDGLREEI 239

Query: 58  RL---SAFQIVEELFVRSHQF--RMLVVSNFQEFLEL--TLGTDPAQPLPPPREAAQRLR 110
           RL     F++ +E     +Q   R   V+ F +F E+  T  T  ++ L   R+A Q+ +
Sbjct: 240 RLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQK 299

Query: 111 QATTRAVEGW-NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDK 169
           +   + +E   +++ G          HFL+ ++++  Q  N  + + +  EEE +    +
Sbjct: 300 EQLRQQLEAPPSQRDG----------HFLQESRRLSAQFENLMAESRQDLEEEYEPQFLR 349

Query: 170 IYQERASQAEREMQEMSGEIE 190
           +  ER     + +Q    EI+
Sbjct: 350 LL-ERKEAGTKALQRTQAEIQ 369


>gi|166706887 syncoilin, intermediate filament 1 isoform 1 [Homo
           sapiens]
          Length = 482

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/201 (22%), Positives = 94/201 (46%), Gaps = 31/201 (15%)

Query: 1   MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLI-AQLTQE--HAEI 57
           ++++  +L+ EL    EP L     +E++++     + +  AY+L   A+L ++    EI
Sbjct: 189 LEEERDQLIHELVLLREPAL-----QEVQQV----HQDILAAYKLHAQAELERDGLREEI 239

Query: 58  RL---SAFQIVEELFVRSHQF--RMLVVSNFQEFLEL--TLGTDPAQPLPPPREAAQRLR 110
           RL     F++ +E     +Q   R   V+ F +F E+  T  T  ++ L   R+A Q+ +
Sbjct: 240 RLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQK 299

Query: 111 QATTRAVEGW-NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDK 169
           +   + +E   +++ G          HFL+ ++++  Q  N  + + +  EEE +    +
Sbjct: 300 EQLRQQLEAPPSQRDG----------HFLQESRRLSAQFENLMAESRQDLEEEYEPQFLR 349

Query: 170 IYQERASQAEREMQEMSGEIE 190
           +  ER     + +Q    EI+
Sbjct: 350 LL-ERKEAGTKALQRTQAEIQ 369


>gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo
           sapiens]
          Length = 652

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 58/263 (22%), Positives = 96/263 (36%), Gaps = 50/263 (19%)

Query: 384 EPEGGERRRTEALGDAEEDEDDEDFVEVPEKEG-----YEPHIPDHLRPEY-------GL 431
           +PE       E   D +EDED+++   + E E        P   D LR E        GL
Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465

Query: 432 EAAPEKDTVVRCLRTR-----TRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPEP 486
           +   E+D  +  L +       R++E+ S       + +++    PPPS        P+P
Sbjct: 466 KKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPS--------PQP 517

Query: 487 QEAQKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADIS 546
            E       R R   +  G       Q+L                K    + + +   + 
Sbjct: 518 TEEDPEHRVRVRVTKLRLGGP----NQDLTVLE-----------MKRENPQLKQIEGLVK 562

Query: 547 EMLRSRHITFAGKFE--PVQHWCRAPRPDGRLCERQD--RLKCPFHGKIVPRDDEGRPLD 602
           E+L    +T AGK E   V+ W        R    +D   LK  F   +VP  +E +   
Sbjct: 563 ELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQ--- 619

Query: 603 PEDRAREQRRQLQKQERPEWQDP 625
              + R+++++L+   R  W  P
Sbjct: 620 ---KERQRQKELESNYRRVWGSP 639


>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 15/46 (32%), Positives = 29/46 (63%)

Query: 139 RHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQE 184
           +  KK D +   A   +++K EEEK+KH ++  +++  QA+R+ +E
Sbjct: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115


>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 15/46 (32%), Positives = 29/46 (63%)

Query: 139 RHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQE 184
           +  KK D +   A   +++K EEEK+KH ++  +++  QA+R+ +E
Sbjct: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 63/289 (21%), Positives = 120/289 (41%), Gaps = 48/289 (16%)

Query: 368 KAELELVLRKYKELDIEPEGGERRRTE-ALGDAEEDED-DEDFVEVPEKEGYEPHIPDHL 425
           K+E+E +  K   L++ P+   R     A G     ED  +D     + E   P  P H 
Sbjct: 97  KSEMEFIESKRPRLELLPDPLLRPSPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHT 156

Query: 426 RPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPE 485
            PE  LE  P + +    ++   R+D E++      ++L++ +  L    +A P    PE
Sbjct: 157 DPE--LELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEE-EAAKP----PE 209

Query: 486 PQEAQKLAAERARAPVVPYGVDL-HYWGQELPTAGKIVKSDSQHR-------------FW 531
           P++           PV P  ++  H    ++       K+++ HR             + 
Sbjct: 210 PEK-----------PVSPPPIESKHRSLVQIIYDENRKKAEAAHRILEGLGPQVELPLYN 258

Query: 532 KPSEVEEEVVNADISEMLRSRHIT-FAGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGK 590
           +PS+  +   N  I++ +R + I  F  +    + W      + + C+R D+L   +  K
Sbjct: 259 QPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQW------EQKFCQRYDQLMEAWEKK 312

Query: 591 IVPRDDEGRPLDPEDRAREQR-RQLQKQERPE-WQDPELMRDVEAATGQ 637
           +     E    +P  RA+E + R+  +++ PE  +  EL   +++  GQ
Sbjct: 313 V-----ERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQ 356


>gi|195963410 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 1 [Homo sapiens]
          Length = 415

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 20/87 (22%)

Query: 204 VPFDF-------DPNPETESLGMASGMSDALRSSCAGQVGPCRSGTPDPRDGEQPCCSRD 256
           +P DF        P+P++E  G++S  S +L S       P  S +P PRD   P  S D
Sbjct: 327 IPLDFPGSFDVLSPSPDSE--GLSSVFSSSLPS-------PTNSSSPSPRD---PTDSLD 374

Query: 257 -LPASAGHPRAGGGAQPSQTATGDPSD 282
            L A +G P  G G  P    + D SD
Sbjct: 375 WLEALSGGPPLGSGPPPPSIFSADLSD 401


>gi|32698970 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 2 [Homo sapiens]
          Length = 312

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 20/87 (22%)

Query: 204 VPFDF-------DPNPETESLGMASGMSDALRSSCAGQVGPCRSGTPDPRDGEQPCCSRD 256
           +P DF        P+P++E  G++S  S +L S       P  S +P PRD   P  S D
Sbjct: 224 IPLDFPGSFDVLSPSPDSE--GLSSVFSSSLPS-------PTNSSSPSPRD---PTDSLD 271

Query: 257 -LPASAGHPRAGGGAQPSQTATGDPSD 282
            L A +G P  G G  P    + D SD
Sbjct: 272 WLEALSGGPPLGSGPPPPSIFSADLSD 298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,348,991
Number of Sequences: 37866
Number of extensions: 1625995
Number of successful extensions: 12255
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 174
Number of HSP's that attempted gapping in prelim test: 11419
Number of HSP's gapped (non-prelim): 953
length of query: 709
length of database: 18,247,518
effective HSP length: 109
effective length of query: 600
effective length of database: 14,120,124
effective search space: 8472074400
effective search space used: 8472074400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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