Guide to the Human Genome
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Search of human proteins with 190358526

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190358526 hypothetical protein LOC54785 [Homo sapiens]
         (357 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190358526 hypothetical protein LOC54785 [Homo sapiens]             717   0.0  
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          53   5e-07
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    49   9e-06
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    49   9e-06
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    49   9e-06
gi|60097902 filaggrin [Homo sapiens]                                   45   8e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      45   1e-04
gi|6912492 mitogen-activated protein kinase 8 interacting protei...    45   1e-04
gi|7706537 mitogen-activated protein kinase 8 interacting protei...    45   1e-04
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              44   2e-04
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    44   2e-04
gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]          44   2e-04
gi|41152235 ubiquitin specific protease 51 [Homo sapiens]              44   3e-04
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H...    44   3e-04
gi|55741677 SET domain containing 1A [Homo sapiens]                    43   4e-04
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s...    43   4e-04
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s...    43   4e-04
gi|239753407 PREDICTED: hypothetical protein [Homo sapiens]            43   5e-04
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             42   6e-04
gi|239508698 PREDICTED: similar to mucin [Homo sapiens]                42   6e-04
gi|169215850 PREDICTED: transmembrane protein 46-like [Homo sapi...    42   8e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    42   8e-04
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]        42   8e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         42   8e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    42   8e-04
gi|239754474 PREDICTED: similar to mucin [Homo sapiens]                42   0.001
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                42   0.001
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]                   42   0.001
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    42   0.001
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       42   0.001

>gi|190358526 hypothetical protein LOC54785 [Homo sapiens]
          Length = 357

 Score =  717 bits (1850), Expect = 0.0
 Identities = 357/357 (100%), Positives = 357/357 (100%)

Query: 1   MESSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRT 60
           MESSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRT
Sbjct: 1   MESSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRT 60

Query: 61  SPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKP 120
           SPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKP
Sbjct: 61  SPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKP 120

Query: 121 SSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAG 180
           SSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAG
Sbjct: 121 SSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAG 180

Query: 181 SSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPAR 240
           SSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPAR
Sbjct: 181 SSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPAR 240

Query: 241 PCPAPAPTPTPAIPPIDPEVLRDLERLSRELGGRVDRLLRGLGGAVQELTALSVGCIQTY 300
           PCPAPAPTPTPAIPPIDPEVLRDLERLSRELGGRVDRLLRGLGGAVQELTALSVGCIQTY
Sbjct: 241 PCPAPAPTPTPAIPPIDPEVLRDLERLSRELGGRVDRLLRGLGGAVQELTALSVGCIQTY 300

Query: 301 RDAVDSLGEAVDMSIKGMYTLLARCEELERALQPVQGLARQVRDIRRTLEVLEALCK 357
           RDAVDSLGEAVDMSIKGMYTLLARCEELERALQPVQGLARQVRDIRRTLEVLEALCK
Sbjct: 301 RDAVDSLGEAVDMSIKGMYTLLARCEELERALQPVQGLARQVRDIRRTLEVLEALCK 357


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 75/264 (28%), Positives = 86/264 (32%), Gaps = 42/264 (15%)

Query: 3   SSRGRPGPETDLLAVAEHQ-ALVFGGGPGRTSS---EPPAGLRVSGEEETENVGGANRHP 58
           SS G  G E   L+ A    A      PGR  S    PP      G       GGA    
Sbjct: 81  SSAGTGGAEPPALSPAPASPARPVSPAPGRRLSLWAVPPGPPLSGGLSPDPKPGGAPTSS 140

Query: 59  RTSPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEG 118
           R    +S       PE  A    PG      G GSRR                 P PP  
Sbjct: 141 RRPLLSSPSWGGPEPEGRAGGGIPGSSSPHPGTGSRRLKVA-------------PPPPAP 187

Query: 119 KP-----SSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLS 173
           KP     +SG     GG G G  +   E E       + S AG   S       S    +
Sbjct: 188 KPCKTVTTSGAKAG-GGKGAGSRLSWPESEGKPRVKGSKSSAGTGASV------SAAATA 240

Query: 174 EACGGAGSSGSAESG--AGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAP 231
            A GG GS+ S   G  AG G R  +S       T+           +N  L        
Sbjct: 241 AAAGGGGSTASTSGGVGAGAGARGKLSPRKGKSKTL-----------DNSDLHPGPPAGS 289

Query: 232 PPPPSAPARPCPAPAPTPTPAIPP 255
           PPP + P  P PA A T   A PP
Sbjct: 290 PPPLTLPPTPSPATAVTAASAQPP 313


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 50/188 (26%), Positives = 66/188 (35%), Gaps = 22/188 (11%)

Query: 27   GGPGRTSSEPPAGLRVSGEEETENVG--GANRHPRTSPKTSSCGVVHRPEREALENEPGP 84
            G  G+T    P G+ V  +  T   G  G   HP         G+     +E  + +PGP
Sbjct: 967  GFQGKTGPPGPGGV-VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1025

Query: 85   QGT--------LSGAGSRRGAPGAEHEPSLSSRH--KNPAPPEGKPSSGRDCRRGGPGG- 133
            QG         L G    RG PGA+  P L      + P  P G P         GP G 
Sbjct: 1026 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1085

Query: 134  -GMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGG 192
             G    Q       E+ A G +  +  + R       DG+    G  G +G A S    G
Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-------DGVQGPVGLPGPAGPAGSPGEDG 1138

Query: 193  RRATISSP 200
             +  I  P
Sbjct: 1139 DKGEIGEP 1146



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 58/227 (25%), Positives = 72/227 (31%), Gaps = 40/227 (17%)

Query: 27   GGPGRTSSEPPAGLRV-SGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQ 85
            G PG+      AG     GE+  +   GA   P  +      G   +P  E L   PGP 
Sbjct: 1369 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1428

Query: 86   GT--LSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEE 143
            G   L GA  + G PG    P L     +P     K   G     G PG     EQ E+ 
Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG-----EQGEKG 1483

Query: 144  DNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSG-SAESGAGGGRRATISSPLE 202
            D       GS   +           + G +   G  G  G     G  G + +T      
Sbjct: 1484 DRGLPGTQGSPGAKG-------DGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST------ 1530

Query: 203  LEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTP 249
              G   + GD               SG P PP S P  P     P P
Sbjct: 1531 --GPAGQKGD---------------SGLPGPPGS-PGPPGEVIQPLP 1559



 Score = 35.4 bits (80), Expect = 0.079
 Identities = 56/226 (24%), Positives = 76/226 (33%), Gaps = 38/226 (16%)

Query: 52  GGANRHPRTSPKTSSCGVVHRPEREALENEPGPQ------GTLSGAGSRRGAPGAEHEPS 105
           G  ++ P  S + +    + +  R AL   PGP       G + G GS  GA G   +P 
Sbjct: 513 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS-SGAKGESGDPG 571

Query: 106 LSSRH--KNPAPPEGKPSSGRDCRRGGPGG-GMDVEQQEEEDNDEEAAAG-----SRAGR 157
                  + P  P GKP  G+  R G  GG GM  E   + D   +   G        G 
Sbjct: 572 PQGPRGVQGPPGPTGKP--GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 629

Query: 158 SFSSRLQDSRSLDGLSEACGGAGSSG-SAESGAGG--GRRATISSPLE-----LEGTVSR 209
                       DG+    G  G  G   E+G  G  G R T  +P +     ++G    
Sbjct: 630 RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 689

Query: 210 HGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPP 255
            G++                  P PP     P P   P P   I P
Sbjct: 690 KGNMG-------------PQGEPGPPGQQGNPGPQGLPGPQGPIGP 722



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 58/253 (22%), Positives = 81/253 (32%), Gaps = 14/253 (5%)

Query: 6    GRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTS 65
            G PG + D   + E       G  G      P GL+  G      + G +  P   P+  
Sbjct: 1132 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEP--GPRGQ 1187

Query: 66   SCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPS---S 122
              G+  +   E     PGP G + G     G PG + E         P PP  +     +
Sbjct: 1188 Q-GMFGQKGDEGARGFPGPPGPI-GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1245

Query: 123  GRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSS 182
            G D  +G PG    V    E+    EA      G +     +  R   G +   G AG  
Sbjct: 1246 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1305

Query: 183  GSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAP----PPPPSAP 238
            G+       G +     P+   G     G+      + +       G P    PP PS  
Sbjct: 1306 GAKGPPGDDGPKGN-PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1364

Query: 239  ARPCPAPAPTPTP 251
            A P   P     P
Sbjct: 1365 AGPPGPPGKRGPP 1377



 Score = 32.7 bits (73), Expect = 0.51
 Identities = 37/140 (26%), Positives = 43/140 (30%), Gaps = 19/140 (13%)

Query: 27   GGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQG 86
            G PG      P G R  GE+      GA   P         G    P       +PGP G
Sbjct: 1276 GPPGEAGVGGPKGER--GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG 1333

Query: 87   TLSGAGS--------RRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVE 138
                AG           G PG    P  S     P PP           RG PG      
Sbjct: 1334 EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK---------RGPPGAAGAEG 1384

Query: 139  QQEEEDNDEEAAAGSRAGRS 158
            +Q E+    EA A    G++
Sbjct: 1385 RQGEKGAKGEAGAEGPPGKT 1404



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 40/155 (25%), Positives = 55/155 (35%), Gaps = 23/155 (14%)

Query: 2   ESSRGRPGPETD---LLAVAEHQALVFGGGPGRTSSEPPAGLR-------VSGEEETENV 51
           E  +GR GP  D        E   L   G PG    + P G          +GE+    V
Sbjct: 825 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 884

Query: 52  GG-----ANRHPRTSPKTS--SCGVVHRPEREAL---ENEPGPQGTLSGAGSRR--GAPG 99
            G       R P T P+ S  + G   +P  +     +  PGP G     G +   G PG
Sbjct: 885 AGKPGPRGQRGP-TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG 943

Query: 100 AEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGG 134
            +  P    +   P  P  +  +G   + G PG G
Sbjct: 944 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 978


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 50/188 (26%), Positives = 66/188 (35%), Gaps = 22/188 (11%)

Query: 27   GGPGRTSSEPPAGLRVSGEEETENVG--GANRHPRTSPKTSSCGVVHRPEREALENEPGP 84
            G  G+T    P G+ V  +  T   G  G   HP         G+     +E  + +PGP
Sbjct: 916  GFQGKTGPPGPGGV-VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974

Query: 85   QGT--------LSGAGSRRGAPGAEHEPSLSSRH--KNPAPPEGKPSSGRDCRRGGPGG- 133
            QG         L G    RG PGA+  P L      + P  P G P         GP G 
Sbjct: 975  QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1034

Query: 134  -GMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGG 192
             G    Q       E+ A G +  +  + R       DG+    G  G +G A S    G
Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-------DGVQGPVGLPGPAGPAGSPGEDG 1087

Query: 193  RRATISSP 200
             +  I  P
Sbjct: 1088 DKGEIGEP 1095



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 58/227 (25%), Positives = 72/227 (31%), Gaps = 40/227 (17%)

Query: 27   GGPGRTSSEPPAGLRV-SGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQ 85
            G PG+      AG     GE+  +   GA   P  +      G   +P  E L   PGP 
Sbjct: 1318 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1377

Query: 86   GT--LSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEE 143
            G   L GA  + G PG    P L     +P     K   G     G PG     EQ E+ 
Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG-----EQGEKG 1432

Query: 144  DNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSG-SAESGAGGGRRATISSPLE 202
            D       GS   +           + G +   G  G  G     G  G + +T      
Sbjct: 1433 DRGLPGTQGSPGAKG-------DGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST------ 1479

Query: 203  LEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTP 249
              G   + GD               SG P PP S P  P     P P
Sbjct: 1480 --GPAGQKGD---------------SGLPGPPGS-PGPPGEVIQPLP 1508



 Score = 35.4 bits (80), Expect = 0.079
 Identities = 56/226 (24%), Positives = 76/226 (33%), Gaps = 38/226 (16%)

Query: 52  GGANRHPRTSPKTSSCGVVHRPEREALENEPGPQ------GTLSGAGSRRGAPGAEHEPS 105
           G  ++ P  S + +    + +  R AL   PGP       G + G GS  GA G   +P 
Sbjct: 462 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS-SGAKGESGDPG 520

Query: 106 LSSRH--KNPAPPEGKPSSGRDCRRGGPGG-GMDVEQQEEEDNDEEAAAG-----SRAGR 157
                  + P  P GKP  G+  R G  GG GM  E   + D   +   G        G 
Sbjct: 521 PQGPRGVQGPPGPTGKP--GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 578

Query: 158 SFSSRLQDSRSLDGLSEACGGAGSSG-SAESGAGG--GRRATISSPLE-----LEGTVSR 209
                       DG+    G  G  G   E+G  G  G R T  +P +     ++G    
Sbjct: 579 RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 638

Query: 210 HGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPP 255
            G++                  P PP     P P   P P   I P
Sbjct: 639 KGNMG-------------PQGEPGPPGQQGNPGPQGLPGPQGPIGP 671



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 58/253 (22%), Positives = 81/253 (32%), Gaps = 14/253 (5%)

Query: 6    GRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTS 65
            G PG + D   + E       G  G      P GL+  G      + G +  P   P+  
Sbjct: 1081 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEP--GPRGQ 1136

Query: 66   SCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPS---S 122
              G+  +   E     PGP G + G     G PG + E         P PP  +     +
Sbjct: 1137 Q-GMFGQKGDEGARGFPGPPGPI-GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1194

Query: 123  GRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSS 182
            G D  +G PG    V    E+    EA      G +     +  R   G +   G AG  
Sbjct: 1195 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1254

Query: 183  GSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAP----PPPPSAP 238
            G+       G +     P+   G     G+      + +       G P    PP PS  
Sbjct: 1255 GAKGPPGDDGPKGN-PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313

Query: 239  ARPCPAPAPTPTP 251
            A P   P     P
Sbjct: 1314 AGPPGPPGKRGPP 1326



 Score = 32.7 bits (73), Expect = 0.51
 Identities = 37/140 (26%), Positives = 43/140 (30%), Gaps = 19/140 (13%)

Query: 27   GGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQG 86
            G PG      P G R  GE+      GA   P         G    P       +PGP G
Sbjct: 1225 GPPGEAGVGGPKGER--GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG 1282

Query: 87   TLSGAGS--------RRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVE 138
                AG           G PG    P  S     P PP           RG PG      
Sbjct: 1283 EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK---------RGPPGAAGAEG 1333

Query: 139  QQEEEDNDEEAAAGSRAGRS 158
            +Q E+    EA A    G++
Sbjct: 1334 RQGEKGAKGEAGAEGPPGKT 1353



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 40/155 (25%), Positives = 55/155 (35%), Gaps = 23/155 (14%)

Query: 2   ESSRGRPGPETD---LLAVAEHQALVFGGGPGRTSSEPPAGLR-------VSGEEETENV 51
           E  +GR GP  D        E   L   G PG    + P G          +GE+    V
Sbjct: 774 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 833

Query: 52  GG-----ANRHPRTSPKTS--SCGVVHRPEREAL---ENEPGPQGTLSGAGSRR--GAPG 99
            G       R P T P+ S  + G   +P  +     +  PGP G     G +   G PG
Sbjct: 834 AGKPGPRGQRGP-TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG 892

Query: 100 AEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGG 134
            +  P    +   P  P  +  +G   + G PG G
Sbjct: 893 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 927


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 50/188 (26%), Positives = 66/188 (35%), Gaps = 22/188 (11%)

Query: 27   GGPGRTSSEPPAGLRVSGEEETENVG--GANRHPRTSPKTSSCGVVHRPEREALENEPGP 84
            G  G+T    P G+ V  +  T   G  G   HP         G+     +E  + +PGP
Sbjct: 955  GFQGKTGPPGPGGV-VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013

Query: 85   QGT--------LSGAGSRRGAPGAEHEPSLSSRH--KNPAPPEGKPSSGRDCRRGGPGG- 133
            QG         L G    RG PGA+  P L      + P  P G P         GP G 
Sbjct: 1014 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1073

Query: 134  -GMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGG 192
             G    Q       E+ A G +  +  + R       DG+    G  G +G A S    G
Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-------DGVQGPVGLPGPAGPAGSPGEDG 1126

Query: 193  RRATISSP 200
             +  I  P
Sbjct: 1127 DKGEIGEP 1134



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 58/227 (25%), Positives = 72/227 (31%), Gaps = 40/227 (17%)

Query: 27   GGPGRTSSEPPAGLRV-SGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQ 85
            G PG+      AG     GE+  +   GA   P  +      G   +P  E L   PGP 
Sbjct: 1357 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1416

Query: 86   GT--LSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEE 143
            G   L GA  + G PG    P L     +P     K   G     G PG     EQ E+ 
Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG-----EQGEKG 1471

Query: 144  DNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSG-SAESGAGGGRRATISSPLE 202
            D       GS   +           + G +   G  G  G     G  G + +T      
Sbjct: 1472 DRGLPGTQGSPGAKG-------DGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST------ 1518

Query: 203  LEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTP 249
              G   + GD               SG P PP S P  P     P P
Sbjct: 1519 --GPAGQKGD---------------SGLPGPPGS-PGPPGEVIQPLP 1547



 Score = 35.4 bits (80), Expect = 0.079
 Identities = 56/226 (24%), Positives = 76/226 (33%), Gaps = 38/226 (16%)

Query: 52  GGANRHPRTSPKTSSCGVVHRPEREALENEPGPQ------GTLSGAGSRRGAPGAEHEPS 105
           G  ++ P  S + +    + +  R AL   PGP       G + G GS  GA G   +P 
Sbjct: 501 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS-SGAKGESGDPG 559

Query: 106 LSSRH--KNPAPPEGKPSSGRDCRRGGPGG-GMDVEQQEEEDNDEEAAAG-----SRAGR 157
                  + P  P GKP  G+  R G  GG GM  E   + D   +   G        G 
Sbjct: 560 PQGPRGVQGPPGPTGKP--GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 617

Query: 158 SFSSRLQDSRSLDGLSEACGGAGSSG-SAESGAGG--GRRATISSPLE-----LEGTVSR 209
                       DG+    G  G  G   E+G  G  G R T  +P +     ++G    
Sbjct: 618 RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 677

Query: 210 HGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPP 255
            G++                  P PP     P P   P P   I P
Sbjct: 678 KGNMG-------------PQGEPGPPGQQGNPGPQGLPGPQGPIGP 710



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 58/253 (22%), Positives = 81/253 (32%), Gaps = 14/253 (5%)

Query: 6    GRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTS 65
            G PG + D   + E       G  G      P GL+  G      + G +  P   P+  
Sbjct: 1120 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEP--GPRGQ 1175

Query: 66   SCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPS---S 122
              G+  +   E     PGP G + G     G PG + E         P PP  +     +
Sbjct: 1176 Q-GMFGQKGDEGARGFPGPPGPI-GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1233

Query: 123  GRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSS 182
            G D  +G PG    V    E+    EA      G +     +  R   G +   G AG  
Sbjct: 1234 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1293

Query: 183  GSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAP----PPPPSAP 238
            G+       G +     P+   G     G+      + +       G P    PP PS  
Sbjct: 1294 GAKGPPGDDGPKGN-PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352

Query: 239  ARPCPAPAPTPTP 251
            A P   P     P
Sbjct: 1353 AGPPGPPGKRGPP 1365



 Score = 32.7 bits (73), Expect = 0.51
 Identities = 37/140 (26%), Positives = 43/140 (30%), Gaps = 19/140 (13%)

Query: 27   GGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQG 86
            G PG      P G R  GE+      GA   P         G    P       +PGP G
Sbjct: 1264 GPPGEAGVGGPKGER--GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG 1321

Query: 87   TLSGAGS--------RRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVE 138
                AG           G PG    P  S     P PP           RG PG      
Sbjct: 1322 EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK---------RGPPGAAGAEG 1372

Query: 139  QQEEEDNDEEAAAGSRAGRS 158
            +Q E+    EA A    G++
Sbjct: 1373 RQGEKGAKGEAGAEGPPGKT 1392



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 40/155 (25%), Positives = 55/155 (35%), Gaps = 23/155 (14%)

Query: 2   ESSRGRPGPETD---LLAVAEHQALVFGGGPGRTSSEPPAGLR-------VSGEEETENV 51
           E  +GR GP  D        E   L   G PG    + P G          +GE+    V
Sbjct: 813 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 872

Query: 52  GG-----ANRHPRTSPKTS--SCGVVHRPEREAL---ENEPGPQGTLSGAGSRR--GAPG 99
            G       R P T P+ S  + G   +P  +     +  PGP G     G +   G PG
Sbjct: 873 AGKPGPRGQRGP-TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG 931

Query: 100 AEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGG 134
            +  P    +   P  P  +  +G   + G PG G
Sbjct: 932 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 966


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 52/198 (26%), Positives = 76/198 (38%), Gaps = 23/198 (11%)

Query: 3    SSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSP 62
            S+ G+ GP         HQ    G   GR+        +VS  E++E+      H R  P
Sbjct: 3680 SAHGQAGPHQQ-----SHQESTRGRSAGRSGRSGSFLYQVSTHEQSESA-----HGRAGP 3729

Query: 63   KTSSC-GVVHRPEREALENEPGPQG--TLSG-AGSRRGA-PGAEHEPSLSSRHKNPAPPE 117
             T    G  H   R++  +    +G  T+ G  GSRRG   G+ HE S+     + +   
Sbjct: 3730 STGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHS 3789

Query: 118  GKPSSGRDCRRGGPGGGMDVEQQ---EEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSE 174
               S GR     G  G     ++   EE+  D    +GSR   + +       S  G  E
Sbjct: 3790 HTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGE 3849

Query: 175  ACGG-----AGSSGSAES 187
            + G       GSS S +S
Sbjct: 3850 SAGSRRSRRQGSSVSQDS 3867



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 51/208 (24%), Positives = 79/208 (37%), Gaps = 21/208 (10%)

Query: 3    SSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSP 62
            S  G+ GP         HQ        GR+        +VS  E++E+      H RT  
Sbjct: 3356 SGHGQAGPHQQ-----SHQESARDRSGGRSGRSGSFLYQVSTHEQSESA-----HGRTRT 3405

Query: 63   KTSSC-GVVHRPEREALENEPGPQG--TLSG--AGSRRGAPGAEHEPSLSSRHKNPAPPE 117
             T    G  H   R++  +    +G  T+ G    SRRG  G+ +E S+     + +   
Sbjct: 3406 STGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHS 3465

Query: 118  GKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACG 177
               S GR     G  G     +Q    NDE++  GSR   S+S   + S   D    +  
Sbjct: 3466 HTTSQGRSDASRGQSGSRSASRQTR--NDEQSGDGSR--HSWSHHHEASTQADSSRHSQS 3521

Query: 178  GAGSSGSAESGAGGGRRATISSPLELEG 205
            G G S    +    G  +++S   + +G
Sbjct: 3522 GQGQSAGPRTSRNQG--SSVSQDSDSQG 3547



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 50/202 (24%), Positives = 75/202 (37%), Gaps = 23/202 (11%)

Query: 3   SSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSP 62
           S  G+ G     L    HQ    G    R+     +  +VS  E+ ++      H RT  
Sbjct: 438 SGHGKAG-----LRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSA-----HGRTGT 487

Query: 63  KTSSC-GVVHRPEREALENEPGPQG--TLSG--AGSRRGAPGAEHEPSLSSRHKNPAPPE 117
            T    G  H   R++  +    +G  T+ G    SR G  G+ HE S++    + +   
Sbjct: 488 STGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHS 547

Query: 118 GKPSSGRDCRRGGPGGGMDVEQQ---EEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSE 174
              S GR     G  G     +Q   EE+  D    +GSR   + S       S  G  +
Sbjct: 548 HTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQ 607

Query: 175 ACG-----GAGSSGSAESGAGG 191
           + G       GSS S +S + G
Sbjct: 608 SSGPRTSRNQGSSVSQDSDSQG 629



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 52/214 (24%), Positives = 76/214 (35%), Gaps = 13/214 (6%)

Query: 3    SSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSP 62
            S  G+ GP         HQ        GR+        +VS  E++E+  G  R   T  
Sbjct: 1087 SGHGQDGPHQQ-----SHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTR-TSTGR 1140

Query: 63   KTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGA-PGAEHEPSLSSRHKNPAPPEGKPS 121
            +  S     R       ++ G     +  GSRRG   G+ HE S+     + +      S
Sbjct: 1141 RQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTS 1200

Query: 122  SGRDCRRGGPGGGMDVEQQEEED---NDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGG 178
             GR     G  G     +Q  +D    D    +GSR   + S       S  G  ++ G 
Sbjct: 1201 QGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGS 1260

Query: 179  AGS--SGSAESGAGGGRRATISSPLELEGTVSRH 210
              S   GS+ S      R +  S   L G+ SR+
Sbjct: 1261 RTSRHQGSSVSQDSDSERHSDDSE-RLSGSASRN 1293



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 48/170 (28%), Positives = 64/170 (37%), Gaps = 30/170 (17%)

Query: 31   RTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREA------LENEPGP 84
            R S       R S +E++ +    +RHPR S      G  H  +R         E   G 
Sbjct: 3230 RWSGSASRNHRGSVQEQSRH---GSRHPR-SHHEDRAGHGHSADRSRQSGTRHAETSSGG 3285

Query: 85   QGTLSGAGSRRGAPGAEHEPSLSSRHKNPAP-------PEGKPSSG-RDCRRGGPGGGM- 135
            Q   S     R +PG  H     SRH+  A        P G+ SS  RD R  G  G   
Sbjct: 3286 QAA-SSHEQARSSPGERH----GSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQA 3340

Query: 136  -DVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGS 184
             D E   EE + +  +   +AG    S  + +R   G     G +G SGS
Sbjct: 3341 SDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSG-----GRSGRSGS 3385



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 40/154 (25%), Positives = 57/154 (37%), Gaps = 11/154 (7%)

Query: 57  HPRTSPKTS-SCGVVHRPEREALENEPGPQG--TLSG--AGSRRGAPGAEHEPSLSSRHK 111
           H  T P T    G  H   R+   +     G  T+ G    SRRG  G+ HE S+     
Sbjct: 807 HGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGH 866

Query: 112 NPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDG 171
           + +      S GR     G  G     +     N+E++  GSR   S          +  
Sbjct: 867 SGSHHSHTTSQGRSDASRGQSGSRSASRTTR--NEEQSRDGSRHSGSRHHEASSHADISR 924

Query: 172 LSEACGGAGSSGSAESGAGGGRRATISSPLELEG 205
            S+A G   S GS  S   G   +++S   + EG
Sbjct: 925 HSQA-GQGQSEGSRTSRRQG---SSVSQDSDSEG 954



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 39/165 (23%), Positives = 60/165 (36%), Gaps = 20/165 (12%)

Query: 31   RTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQGTLSG 90
            R S       R S +E++ +    +RHPR S      G  H  +       P  + +  G
Sbjct: 961  RWSGSASRNHRGSAQEQSRH---GSRHPR-SHHEDRAGHGHSADSSRQSGTPHAETSSGG 1016

Query: 91   AGSR-----RGAPG----AEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGM--DVEQ 139
              +      R +PG    + H+ S  S   +  P     S+ RD    G  G    D E 
Sbjct: 1017 QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEG 1076

Query: 140  QEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGS 184
              EE + +  +   + G    S  + +R   G     G +G SGS
Sbjct: 1077 HSEESDTQSVSGHGQDGPHQQSHQESARDWSG-----GRSGRSGS 1116



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 52/226 (23%), Positives = 81/226 (35%), Gaps = 32/226 (14%)

Query: 2    ESSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEE--ETENVGGANRHPR 59
            ++S G+ GP +     A  Q         R   +   G R SG    E     G++RH +
Sbjct: 1529 DASHGQSGPRS-----ASRQT--------RNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQ 1575

Query: 60   TSPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSL--SSRH--KNP-A 114
                 S+     R +  ++  +   +G    +  R  +    H  S    SRH  +NP +
Sbjct: 1576 VGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRS 1635

Query: 115  PPEGKPSSGRDC---RRGGP------GGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQD 165
              E + S G      R+ G        GG     QE+  +      GSR  +S  S    
Sbjct: 1636 HQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDS 1695

Query: 166  SRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHG 211
                   S   G +G+ GS+ S A      +  S  +   +VS HG
Sbjct: 1696 GTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQ---SVSAHG 1738



 Score = 32.7 bits (73), Expect = 0.51
 Identities = 56/206 (27%), Positives = 84/206 (40%), Gaps = 26/206 (12%)

Query: 27   GGPGRTSSEPPAGL-RVSGEEETENVGGANRHPRTSPKTSSC-GVVHRPEREALENEPGP 84
            G  G TS    + L +VS  E++E+      H  T P T    G  H   +++  +    
Sbjct: 3050 GRSGETSGHSGSFLYQVSTHEQSES-----SHGWTGPSTRGRQGSRHEQAQDSSRHSASQ 3104

Query: 85   QG--TLSG--AGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGR-DCRRG--GPGGGMDV 137
             G  T+ G    SR G  G  HE S+ S   + +      S GR D  RG  G       
Sbjct: 3105 YGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRT 3164

Query: 138  EQQEEEDNDEEAAAGSR--AGRSFSSRLQDSRSLDGLSEACGGA---GSSGSAESGAGG- 191
             + EE+  D    + SR     + +   + S+++ G SE    +   GSS S +S + G 
Sbjct: 3165 TRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH 3224

Query: 192  ---GRRATISSPLELEGTV---SRHG 211
                 R + S+     G+V   SRHG
Sbjct: 3225 SEDSERWSGSASRNHRGSVQEQSRHG 3250



 Score = 32.0 bits (71), Expect = 0.87
 Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 39/193 (20%)

Query: 33  SSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQGTLSGAG 92
           S    AGLR    +E+       R  R+           +P+     +  G  GT +G  
Sbjct: 438 SGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPD-----SAHGRTGTSTG-- 490

Query: 93  SRRGAPGAEHEPSL-SSRHKNPAPPEGKPSSGRDCRRGGPG---GGMDVEQQEEEDNDEE 148
              G  G+ HE +  SSRH            G+D  RG PG   GG      E+  N   
Sbjct: 491 ---GRQGSHHEQARDSSRHS-------ASQEGQDTIRGHPGSSRGGRQGSHHEQSVN--- 537

Query: 149 AAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSA------ESGAGGGRRATISSPLE 202
                R+G S S       +  G S+A  G   S SA      E  +G G R + S   E
Sbjct: 538 -----RSGHSGSH--HSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHE 590

Query: 203 L--EGTVSRHGDL 213
              +   SRH  +
Sbjct: 591 ASSQADSSRHSQV 603



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 32/127 (25%), Positives = 47/127 (37%), Gaps = 23/127 (18%)

Query: 93   SRRGAPGAEHEPSL-SSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAA 151
            S RG  G+ HE +  SSRH            G+D  RG PG      Q    ++  +++ 
Sbjct: 2758 STRGRQGSRHEQAQDSSRHS-------ASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSG 2810

Query: 152  GSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSA--------ESGAGGGRRATISSPLEL 203
             S +  S ++         G S+A  G   S SA        +SG G     +       
Sbjct: 2811 HSGSHHSHTTS-------QGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEAST 2863

Query: 204  EGTVSRH 210
               +SRH
Sbjct: 2864 HADISRH 2870



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 44/192 (22%), Positives = 67/192 (34%), Gaps = 21/192 (10%)

Query: 39   GLRVSGEE--ETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQG------TLSG 90
            G R SG    E  +   ++RH       SS     RP   ++  +   +G        SG
Sbjct: 2202 GSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSG 2261

Query: 91   AGSRRGAPGAEHEPSLSSRHKNPAPPE--GKPSSGRDCRRGGPGGGMDVEQQEEEDNDEE 148
            + SR     A+ +    SRH      +  G   S    R+ G     +    +   + E+
Sbjct: 2262 SASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQ 2321

Query: 149  A--AAGSRAGRSFSSRLQDSRSLDGLSEA--------CGGAGSSGSAESGAGGGRRATIS 198
            A  +AG R G S   +  DS    G+            G  GSSGS  S + G    + +
Sbjct: 2322 ARSSAGERHG-SHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDT 2380

Query: 199  SPLELEGTVSRH 210
              +   G    H
Sbjct: 2381 QSVSAHGQAGPH 2392



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 24/116 (20%), Positives = 44/116 (37%), Gaps = 2/116 (1%)

Query: 57  HPRTSPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPP 116
           H  ++  +   G  H     + +     +   S AG R G+   + + + SSRH      
Sbjct: 670 HGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRH-QLQSADSSRHSGTGHG 728

Query: 117 EGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAG-SRAGRSFSSRLQDSRSLDG 171
           +   +      RG  G      +   ED+D ++ +G  +AG    S  + +R   G
Sbjct: 729 QASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG 784


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 72/291 (24%), Positives = 93/291 (31%), Gaps = 47/291 (16%)

Query: 6    GRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLR-VSGEEETENVGGANRHPRTSPKT 64
            G PGP+     +A  + +V  G PG+       GL   SGE   +   GA+         
Sbjct: 947  GTPGPQ----GIAGQRGVV--GLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 65   SSCGVVHRPEREALENEPGPQGTLS-----GAGSRRGAPGAEHEPSLSSRHKNPAP--PE 117
               G+   P     E  PG +G+       GA   RG  G    P        P P  P 
Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPA 1060

Query: 118  GKPSSGRDCRRGGPGG-----------GMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQD- 165
            GK     +    GP G           G    + ++ +  E+   G +  R FS  LQ  
Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSG-LQGP 1119

Query: 166  -----SRSLDGLSEACGGAGSSGSAESGAGGGRRAT--ISSPLELEGTVSRHGDLTHFVA 218
                 S    G S A G AG  G   S    G+     +  P+   G   R GD      
Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPV-- 1177

Query: 219  NNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPPIDPEVLRDLERLSR 269
                        PP PP  P  P P  A      +P    E   D  R  R
Sbjct: 1178 -----------GPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYR 1217



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 71/255 (27%), Positives = 82/255 (32%), Gaps = 53/255 (20%)

Query: 27   GGPGRTSSE-PPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALEN----- 80
            G PG      PP      G    +   GA   P         GVV  P +          
Sbjct: 917  GRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976

Query: 81   ----EPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGG-GM 135
                EPG QG  SGA   RG PG    P L       A P G+  SGR+   G  G  G 
Sbjct: 977  GPSGEPGKQGP-SGASGERGPPGPMGPPGL-------AGPPGE--SGREGAPGAEGSPGR 1026

Query: 136  DVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGS-AESGAGG--- 191
            D     + D  E   AG             +    G     G AG SG   E+G  G   
Sbjct: 1027 DGSPGAKGDRGETGPAGP----------PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG 1076

Query: 192  -----GRR--ATISSPLELEGTVSRHGD---LTHFVANNLQLKIRLSGAPPPPPSAPARP 241
                 G R  A    P   +G     GD     H   + LQ        PP PP +P   
Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQ-------GPPGPPGSPGEQ 1129

Query: 242  CPAPAPTPT-PAIPP 255
             P+ A  P  P  PP
Sbjct: 1130 GPSGASGPAGPRGPP 1144



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 62/253 (24%), Positives = 76/253 (30%), Gaps = 51/253 (20%)

Query: 5   RGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKT 64
           RG PGP                G PG    + P G    GE       G    P    K 
Sbjct: 187 RGLPGPP---------------GAPGPQGFQGPPG--EPGEPGASGPMGPRGPPGPPGKN 229

Query: 65  SSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLS-----SRHKNPAPPEGK 119
              G   +P R      PGPQG   G     G PG +     S          PA P+G+
Sbjct: 230 GDDGEAGKPGRPGERGPPGPQGA-RGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE 288

Query: 120 PSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGA 179
           P S  +   G PG                   G R GR  +     +R  DG + A G  
Sbjct: 289 PGSPGE--NGAPG-----------QMGPRGLPGER-GRPGAPGPAGARGNDGATGAAGPP 334

Query: 180 GSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAP-PPPPSAP 238
           G +G A              P    G V   G+         +    + G P PP P+  
Sbjct: 335 GPTGPA-------------GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA 381

Query: 239 ARPCPAPAPTPTP 251
           A P   P     P
Sbjct: 382 AGPAGNPGADGQP 394



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 65/284 (22%), Positives = 86/284 (30%), Gaps = 51/284 (17%)

Query: 6   GRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLR-------------VSGEEETENVG 52
           G PG +    A   + A    G PG   +  P+G +               G   ++   
Sbjct: 386 GNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDT 445

Query: 53  GANRHPRTSPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSS---- 108
           GA   P         G      +     EPGP G L G    RG PG+   P        
Sbjct: 446 GAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTG-LPGPPGERGGPGSRGFPGADGVAGP 504

Query: 109 -------RHKNPAPPEGKP-SSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFS 160
                      PA P+G P  +GR    G PG             D +      AG+   
Sbjct: 505 KGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGR 564

Query: 161 SRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANN 220
                     G +   G  G  G+A      G R  +  P    G   + G+        
Sbjct: 565 PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG-VPGPPGAVGPAGKDGE-------- 615

Query: 221 LQLKIRLSGAP-PPPPSAPA----RPCPAPAP----TPTPAIPP 255
                  +GA  PP P+ PA       PA +P     P PA PP
Sbjct: 616 -------AGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP 652



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 37/135 (27%), Positives = 47/135 (34%), Gaps = 17/135 (12%)

Query: 1   MESSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRT 60
           +   RGRPG      A     A    G PG T    P G   +       VG        
Sbjct: 306 LPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGA-------VGAKGEAGPQ 358

Query: 61  SPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNP--APPEG 118
            P+ S          + +  EPGP G  +GA    G PGA+ +P     +  P  A   G
Sbjct: 359 GPRGSE-------GPQGVRGEPGPPGP-AGAAGPAGNPGADGQPGAKGANGAPGIAGAPG 410

Query: 119 KPSSGRDCRRGGPGG 133
            P +       GPGG
Sbjct: 411 FPGARGPSGPQGPGG 425



 Score = 35.8 bits (81), Expect = 0.061
 Identities = 71/298 (23%), Positives = 91/298 (30%), Gaps = 34/298 (11%)

Query: 27   GGPGRTS-SEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQ 85
            G PG    + PP  +   G    +   G+   P  +    + G V  P        PGP 
Sbjct: 839  GPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP 898

Query: 86   GTLSGAGSR--RGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEE 143
            G     G +  RG  G    P        P P   K S G D   G PG           
Sbjct: 899  GPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPG----------- 947

Query: 144  DNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLEL 203
                +  AG R       + +  R   GL    G  G  G   SGA G R      P+  
Sbjct: 948  TPGPQGIAGQRGVVGLPGQ-RGERGFPGLPGPSGEPGKQG--PSGASGERGP--PGPMGP 1002

Query: 204  EGTVSRHGDLTHFVANNLQLKIRLSGAPPPP----PSAPARPCPAPAPTPTPAIPPIDPE 259
             G     G+     A   +      G+P        + PA P  AP     P   P+ P 
Sbjct: 1003 PGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG--PVGP- 1059

Query: 260  VLRDLERLSRELGGRVDRLLRGLGGAVQELTALSVGCIQTYRDAVDSLGEAVDMSIKG 317
                    + + G R +    G  G V  + A      Q  R      GE  D  IKG
Sbjct: 1060 --------AGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKG 1109



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 33/128 (25%), Positives = 42/128 (32%), Gaps = 18/128 (14%)

Query: 5   RGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKT 64
           RG PGP                G PG       AGL        + + G+   P    KT
Sbjct: 511 RGSPGPAGPK------------GSPGEAGRPGEAGL-----PGAKGLTGSPGSPGPDGKT 553

Query: 65  SSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGR 124
              G   +  R      PG +G  +G     G  GA  EP  +     P PP     +G+
Sbjct: 554 GPPGPAGQDGRPGPPGPPGARGQ-AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK 612

Query: 125 DCRRGGPG 132
           D   G  G
Sbjct: 613 DGEAGAQG 620



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 48/193 (24%), Positives = 64/193 (33%), Gaps = 41/193 (21%)

Query: 79  ENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPP--EGKP-------SSGRDCRRG 129
           + E GP G     G+R GAPG   EP          PP  +G+P        +G     G
Sbjct: 781 KGESGPSGPAGPTGAR-GAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAG 839

Query: 130 GPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSA---- 185
            PG            N    A G++  R  S+    +    G +   G  G SG+A    
Sbjct: 840 PPGPAGPAGPPGPIGN--VGAPGAKGARG-SAGPPGATGFPGAAGRVGPPGPSGNAGPPG 896

Query: 186 ---ESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPC 242
               +G  GG+      P    G   R G++               G P PP  A  +  
Sbjct: 897 PPGPAGKEGGK-----GPRGETGPAGRPGEV---------------GPPGPPGPAGEKGS 936

Query: 243 P-APAPTPTPAIP 254
           P A  P   P  P
Sbjct: 937 PGADGPAGAPGTP 949


>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
           isoform 1 [Homo sapiens]
          Length = 824

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 51/173 (29%), Positives = 73/173 (42%), Gaps = 28/173 (16%)

Query: 29  PGRTSSEP----PAGLRVS---GEEETENVGGANR-HPRTSPKTSSCGVVHRPEREALEN 80
           P  +  EP    P  LR++    ++   N GG +   P +  +T+ C     P  EAL  
Sbjct: 126 PSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCS----PAPEALRE 181

Query: 81  EPGP-QGTLSGAGSRRGA--PGAEHEPSLSSRHKNPAPPEGKPSSG-------RDCRRGG 130
            PGP   T +G G  +    PG + E +  +  + PAP    PSS        R    GG
Sbjct: 182 LPGPLPATDTGPGGAQSPVRPGCDCEGNRPA--EPPAPGGTSPSSDPGIEADLRSRSSGG 239

Query: 131 PGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSG 183
            GG    ++     +D E A G+R GR  SS  +    L     + GG+ SSG
Sbjct: 240 RGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELEL----SSDGGSSSSG 288


>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
           isoform 2 [Homo sapiens]
          Length = 797

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 51/173 (29%), Positives = 73/173 (42%), Gaps = 28/173 (16%)

Query: 29  PGRTSSEP----PAGLRVS---GEEETENVGGANR-HPRTSPKTSSCGVVHRPEREALEN 80
           P  +  EP    P  LR++    ++   N GG +   P +  +T+ C     P  EAL  
Sbjct: 99  PSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCS----PAPEALRE 154

Query: 81  EPGP-QGTLSGAGSRRGA--PGAEHEPSLSSRHKNPAPPEGKPSSG-------RDCRRGG 130
            PGP   T +G G  +    PG + E +  +  + PAP    PSS        R    GG
Sbjct: 155 LPGPLPATDTGPGGAQSPVRPGCDCEGNRPA--EPPAPGGTSPSSDPGIEADLRSRSSGG 212

Query: 131 PGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSG 183
            GG    ++     +D E A G+R GR  SS  +    L     + GG+ SSG
Sbjct: 213 RGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELEL----SSDGGSSSSG 261


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 62/208 (29%), Positives = 82/208 (39%), Gaps = 37/208 (17%)

Query: 3   SSRGRPGPETDLLAVAEHQALVFGGGPGRTSSE--PPAGLRVSGEEETENVGGANRHPRT 60
           ++R   G  T L +V + Q         +T S   PPA +R  G       GGA +    
Sbjct: 56  ATRSPVGAGTKLNSVRQQQLQQQQQQGNKTGSRTGPPASIRGGG-------GGAEKATPL 108

Query: 61  SPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEP-----SLSSRHKNPAP 115
           +PK ++ G V +P   A   E  P  TL+  G RR  PG   EP     S+ S+   P P
Sbjct: 109 APKGAAPGAV-QPVAGA---EAAPAATLAALGGRR--PGPPEEPPRELESVPSKLGEP-P 161

Query: 116 PEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEE-------AAAGSRA---GRSFSSRLQD 165
           P G+   G     GG GGG      E E    +          G RA   G S       
Sbjct: 162 PLGEGGGG-----GGEGGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASP 216

Query: 166 SRSLDGLSEACG-GAGSSGSAESGAGGG 192
           S S     +  G G+ +SGS  +G G G
Sbjct: 217 SPSSSSAGKTPGTGSRNSGSGVAGGGSG 244



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 53/201 (26%), Positives = 62/201 (30%), Gaps = 46/201 (22%)

Query: 29  PGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQGTL 88
           P +    PP G    G  E    GG +                  ERE    +P P    
Sbjct: 154 PSKLGEPPPLGEGGGGGGEGGGAGGGSG-----------------EREGGAPQPPPPRGW 196

Query: 89  SGAGSR---RGAPGAEH-EPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGG--------MD 136
            G G R   RG  G E   PS SS      P  G  +SG     GG GGG        + 
Sbjct: 197 RGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQ 256

Query: 137 VEQQEEEDNDEEAAAGSRA-------GRSFSSRLQDSRSLDGLSE----------ACGGA 179
            E  +     E AAA + A       G   SSR         + E          A    
Sbjct: 257 SELIQFHLKKERAAAAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAE 316

Query: 180 GSSGSAESGAGGGRRATISSP 200
           G   SAE  A GG     + P
Sbjct: 317 GPQQSAEGSASGGGMQAAAPP 337


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 91/340 (26%), Positives = 115/340 (33%), Gaps = 57/340 (16%)

Query: 3    SSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRT-- 60
            S RGR GP      V E +    GG P   S   PA  +        +   +   P    
Sbjct: 1102 SGRGRKGPLVKQTKV-EGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIII 1160

Query: 61   -SPKTSSCGVVHRPEREALE--NEPGPQGTLSGAGSRRG-APGAEHEPSLSSRHKNPAPP 116
             +P TSS G   +      E   +P P G   G GS    AP     P   S    PA P
Sbjct: 1161 KAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASP 1220

Query: 117  EGKPSSGRDCRRGGP-------GGGMDVEQQEE-------EDNDEEAAAGSRA-GRSFSS 161
             G  +     + G          GG   E +         +  DE+   G    G +   
Sbjct: 1221 SGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGP 1280

Query: 162  RLQDSRSLDG----------LSEACGGAG----SSGSAESGAGGGRRATIS----SPL-- 201
            RL+ S+S+D           L  A  GAG     +GS   G GGG  A  S     PL  
Sbjct: 1281 RLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVH 1340

Query: 202  ELEGTVSRHGDLTHFVANNLQLKIRLS----GAPPPPPSAPARPCPAPAPTPTPAIPPID 257
             L G                +  ++ S    GAP PPP  P+    AP PTP    P   
Sbjct: 1341 PLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAH 1400

Query: 258  PEVLRDL------ERLSRELGGRVDRLLRGLGGAVQELTA 291
             E +  L      +   RELG R      GLG   + L A
Sbjct: 1401 HEPVLRLWGASPPDPARRELGYRA-----GLGSQEKSLPA 1435



 Score = 36.2 bits (82), Expect = 0.046
 Identities = 48/210 (22%), Positives = 71/210 (33%), Gaps = 37/210 (17%)

Query: 71   HRPEREA--LENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRR 128
            H PE E     ++P P+  L    S RG  G             P+P  G PS       
Sbjct: 1022 HPPEMETGGSPDDPPPRLALGPQPSLRGWRGG-----------GPSPTPGAPSPSHHGSA 1070

Query: 129  GGPGGGMDVEQQEEEDNDEEAAAG-----SRAGRSFSSRLQDSRSLDGLSEACGGAGSSG 183
            GG GG               AA+      +R+GR     L     ++G  +  GG   + 
Sbjct: 1071 GGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAP 1130

Query: 184  SAESGAGGGRRATISSPLELEG-----------TVSRHGDLTHFVANNLQLKIRL----- 227
            S  S A       +++P E              + S  G  +   +   +   +      
Sbjct: 1131 SPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGG 1190

Query: 228  ---SGAPPPPPSAPARPCPAPAPTPTPAIP 254
                G+ P P  A +   P+P+P PTPA P
Sbjct: 1191 GGGGGSSPSPAPAMSPVPPSPSPVPTPASP 1220



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 195  ATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAP--PPPPSAPARPCPAP-APTPTP 251
            A  ++P  L+ T S    LT + +    L    S AP  P PP  PA   PAP AP P P
Sbjct: 1609 AVAAAPPTLDSTAS---SLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGP 1665

Query: 252  AIPP 255
              PP
Sbjct: 1666 DPPP 1669



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 16/116 (13%)

Query: 27  GGPGRTSSEPPAGLRVSGEEETE-------NVGGANRHPRTSPKTSSCGVVHRPEREALE 79
           G PG   + PPA LR + +           +  GA       P + S G      + +  
Sbjct: 422 GPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQG----QSQPSAP 477

Query: 80  NEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAP--PEGKPSSGRDCRRGGPGG 133
                 GTL  A S RGA      PS   RH   A   P G+PSS    R G  GG
Sbjct: 478 TTKLSSGTLRSASSPRGARA--RSPS-RGRHPEDAKRQPRGRPSSSGTPREGPAGG 530



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 30/139 (21%)

Query: 97   APGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAG 156
            APG  H P   +     AP    P  G D   G   G  +V+ +   D+  E        
Sbjct: 1641 APGDPHPPGPPAP---AAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLET------- 1690

Query: 157  RSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHF 216
                  +  + +L  LS   GG+       +G GGG  A ++S  EL  T   + D   F
Sbjct: 1691 ------ISSASTLSSLSAEGGGS-------AGGGGGAGAGVASGPELLDTYVAYLDGQAF 1737

Query: 217  VANNLQLKIRLSGAPPPPP 235
              ++       +  PP PP
Sbjct: 1738 GGSS-------TPGPPYPP 1749


>gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
          Length = 430

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 56/202 (27%), Positives = 70/202 (34%), Gaps = 23/202 (11%)

Query: 79  ENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVE 138
           E EPG      G    R  PG E  P+L  R K    PE          RG     +   
Sbjct: 22  ELEPGCGSPGRGRRGPRPGPGDEAAPALGRRGKGSGGPEAGADGLSRGERGPRRAAVPEL 81

Query: 139 QQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGS-AESGAG----GGR 193
             +   +   + AGS  G    S      SL G  +  G   S  S    G G    G  
Sbjct: 82  SAQPAGSPRASLAGSDGGGGGGSARSSGISL-GYDQRHGSPRSGRSDPRPGPGPPSVGSA 140

Query: 194 RATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAI 253
           R+++SS L   G+   + D                GA P P  +P    PAP P P   +
Sbjct: 141 RSSVSS-LGSRGSAGAYADFLP------------PGACPAPARSPEPAGPAPFPLPALPL 187

Query: 254 PP----IDPEVLRDLERLSREL 271
           PP          R LE L+REL
Sbjct: 188 PPGREGGPSAAERRLEALTREL 209


>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
          Length = 711

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 44/131 (33%), Positives = 53/131 (40%), Gaps = 10/131 (7%)

Query: 129 GGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESG 188
           GG GG    E  E+    EEAAAG  A ++ S R  +   L+ L E    A       S 
Sbjct: 20  GGGGGASPEEAVEKAGKMEEAAAG--ATKASSRREAEEMKLEPLQER-EPAPEENLTWSS 76

Query: 189 AGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAP----PPPPSAPARPCPA 244
           +GG  +   S PL    + S             Q + R    P    PPPP  PARP P 
Sbjct: 77  SGGDEKVLPSIPLRCHSSSSPVCPRRK-PRPRPQPRARSRSQPGLSAPPPP--PARPPPP 133

Query: 245 PAPTPTPAIPP 255
           P P P PA  P
Sbjct: 134 PPPPPPPAPRP 144


>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
           sapiens]
          Length = 425

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 39/141 (27%), Positives = 52/141 (36%), Gaps = 11/141 (7%)

Query: 109 RHKNPAPPEGKPSSGRDCRRGGPGG-GMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSR 167
           R    +    +PS  RD   GGPGG G             + + GS A     +      
Sbjct: 272 RRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGG 331

Query: 168 SLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRL 227
           ++     A GGAG  G    GAG  R    +S     G ++ H          + + +  
Sbjct: 332 AVGAFGGAAGGAGGGGGGGGGAGAERDRGGAS-----GFLTLHNAFPKEAGGGVTVTV-- 384

Query: 228 SGAPPPPPSAPARPCP-APAP 247
               PP P APA P P APAP
Sbjct: 385 --TGPPAPPAPAPPAPSAPAP 403


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 57/241 (23%), Positives = 91/241 (37%), Gaps = 17/241 (7%)

Query: 21   QALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALEN 80
            +A  FG G       P    +V  +E +E +  A+   R  P T +      PE+E    
Sbjct: 876  EAFAFGSGLRGALRLP--SFKVKRKEPSE-ISEASEEKRPRPSTPAEEDEDDPEQEKEAG 932

Query: 81   EPGPQGTLSGA-GSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQ 139
            EPG  GT        RG    +H  S +   +     + + SS +D          + ++
Sbjct: 933  EPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQ-ESSSEKD---------EEDDE 982

Query: 140  QEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISS 199
            ++EED D E A  +    +  S  +D  S D  S+    A S G  +S +     ++ SS
Sbjct: 983  EDEEDEDREEAVDTTKKETEVSDGEDEES-DSSSKCSLYADSDGENDSTSDSESSSSSSS 1041

Query: 200  PLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPPIDPE 259
                  + S     +   +++   +      P   PSA   P   P PTP P   P+   
Sbjct: 1042 SSSSSSSSSSSSSSSSSESSSEDEEEE--ERPAALPSASPPPREVPVPTPAPVEVPVPER 1099

Query: 260  V 260
            V
Sbjct: 1100 V 1100



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 55/240 (22%), Positives = 81/240 (33%), Gaps = 43/240 (17%)

Query: 29  PGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGP---- 84
           P  TS  PP   R + ++       A       P     G    PERE +   P P    
Sbjct: 407 PSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPA 466

Query: 85  -QGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEE 143
             G+ +   +    P A+H  SL SR +     +    S             D E++EE 
Sbjct: 467 RSGSPAPETTNESVPFAQHS-SLDSRIEMLLKEQRSKFSFL---------ASDTEEEEEN 516

Query: 144 --------DNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRA 195
                   D   E  +GS  G   +     +   D      G  G++  +    G  + +
Sbjct: 517 SSMVLGARDTGSEVPSGSGHGPC-TPPPAPANFEDVAPTGSGEPGATRESPKANGQNQAS 575

Query: 196 TISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPP 255
             SS  ++E +    G                 G+PPP P+ P +P P P P P P  PP
Sbjct: 576 PCSSGDDMEISDDDRG-----------------GSPPPAPTPPQQPPPPPPPPPPP--PP 616


>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
           sapiens]
          Length = 634

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 59/251 (23%), Positives = 91/251 (36%), Gaps = 47/251 (18%)

Query: 28  GPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQGT 87
           G G  S + P  L    E++ EN    +  P       S     RP+ +  ++   P+G 
Sbjct: 121 GNGSVSEKTPP-LEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGA 179

Query: 88  LSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDE 147
            +GA S +G      + +  +  K    P  KP+S R+  R   G            +  
Sbjct: 180 TAGA-SHKGDEVPPIKKNTKAPGKQAPVPPPKPAS-RNTTREAAGS-----------SHS 226

Query: 148 EAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRAT--------ISS 199
           +   GS+A  S S+    SR           AG+ G+ +     G+R T        +SS
Sbjct: 227 KKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTK-----GKRKTDKQPITSHLSS 281

Query: 200 PLELEGTVSRHGDLTHFVANNLQLKIRLSGAP-----------PPPPSAPARPCPAPAPT 248
                GT    G+       + +L+  + GA            PPPP APA         
Sbjct: 282 DTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPA--------- 332

Query: 249 PTPAIPPIDPE 259
           P+P  PP+  E
Sbjct: 333 PSPLAPPLPLE 343


>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
           sapiens]
          Length = 645

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 59/251 (23%), Positives = 91/251 (36%), Gaps = 47/251 (18%)

Query: 28  GPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQGT 87
           G G  S + P  L    E++ EN    +  P       S     RP+ +  ++   P+G 
Sbjct: 132 GNGSVSEKTPP-LEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGA 190

Query: 88  LSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDE 147
            +GA S +G      + +  +  K    P  KP+S R+  R   G            +  
Sbjct: 191 TAGA-SHKGDEVPPIKKNTKAPGKQAPVPPPKPAS-RNTTREAAGS-----------SHS 237

Query: 148 EAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRAT--------ISS 199
           +   GS+A  S S+    SR           AG+ G+ +     G+R T        +SS
Sbjct: 238 KKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTK-----GKRKTDKQPITSHLSS 292

Query: 200 PLELEGTVSRHGDLTHFVANNLQLKIRLSGAP-----------PPPPSAPARPCPAPAPT 248
                GT    G+       + +L+  + GA            PPPP APA         
Sbjct: 293 DTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPA--------- 343

Query: 249 PTPAIPPIDPE 259
           P+P  PP+  E
Sbjct: 344 PSPLAPPLPLE 354


>gi|239753407 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 182

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 48/186 (25%), Positives = 69/186 (37%), Gaps = 30/186 (16%)

Query: 114 APPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLS 173
           APP    ++      GGP        Q  + N   A A      + SS           S
Sbjct: 3   APPATAATAAGGATGGGPQAARRSGVQGGQRNSTSARAPPPPPLAPSS-----------S 51

Query: 174 EACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPP 233
            + G +GSSG   SG+ G  + T+ S L +     R  +     A    L+ R    P  
Sbjct: 52  SSSGSSGSSGGGGSGSAG--QPTLGSMLAVGSAARRASERAGGRAGGTALRAREPPPPLL 109

Query: 234 PPSAPARP------CPAPAPTPTPAI-----PPIDPEVLRDLERLSRELGGRVDRLLRGL 282
           PP +P +P       P P P+P P +     PP  P   +D        GG  +R+L   
Sbjct: 110 PPPSPPQPGPKGPASPRPLPSPLPLLETTPFPPDTPSRRQD------RRGGGEERVLLSA 163

Query: 283 GGAVQE 288
             +V+E
Sbjct: 164 LSSVRE 169


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 232  PPPPSAPARPCPAPAPTPTPAIPPIDPEVLRDLERLSRELGGRVDRLLRGLGGAVQELTA 291
            P P  +P    P  APTP   +   +P  L +L    R++GG++ RL + +    QE  A
Sbjct: 1461 PTPGQSPGPHGPCVAPTPPVRVMACEPPALVELVAAVRDVGGQLQRLTQVVEQERQERQA 1520

Query: 292  LSVGCIQTYRDA--VDSLGEAV 311
            L +G  Q    A  +  LGEAV
Sbjct: 1521 LLLGLTQLVEAARGLGQLGEAV 1542



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 3/97 (3%)

Query: 26   GGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQ 85
            G G  R+   PP  LRV G+  +       R P     T +      P   A    PGP 
Sbjct: 963  GAGTTRSPGSPPT-LRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGP- 1020

Query: 86   GTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSS 122
              L+   SR   P +      +S   + +PP   P+S
Sbjct: 1021 -ALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPAS 1056



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 16/103 (15%)

Query: 165  DSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLK 224
            D+ S  GL+E    AG  G      G G   +  SP     T+  HGD           K
Sbjct: 941  DTPSGRGLAEGTPTAGKLGPT---LGAGTTRSPGSP----PTLRVHGD------TGSPRK 987

Query: 225  IRLSGAPPPPPS---APARPCPAPAPTPTPAIPPIDPEVLRDL 264
                  PP P +   AP  P P P+ +P P  P +  +  R+L
Sbjct: 988  PWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTSDSSREL 1030


>gi|239508698 PREDICTED: similar to mucin [Homo sapiens]
          Length = 265

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 45/179 (25%), Positives = 66/179 (36%), Gaps = 16/179 (8%)

Query: 34  SEPPAGLRVSGEEETENVGGAN--RHPRTSPKTSSCGVVHRPEREALENEPGPQGTLSGA 91
           +E    LR   + + +  GG    R   +SP     G   R E  A      P      A
Sbjct: 27  NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA----APAADQQRA 82

Query: 92  GSRRGAPGAEHEPSLSSRH---KNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEE 148
             R     A   P+ S      + P  P+ +P+ G   RRG  G     +QQ  +D +EE
Sbjct: 83  QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGS-GSSPSADQQGAQDREEE 141

Query: 149 AAAG----SRAGRSFSSRLQ--DSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPL 201
           AAA     SR  R+   + Q    R   G  +  G   S  + + GA        ++P+
Sbjct: 142 AAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPV 200



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 31/119 (26%), Positives = 47/119 (39%), Gaps = 15/119 (12%)

Query: 94  RRGAPGAEHEPSLSSRHKNPAPPEGKPS---SGRDCRRGGPGGGMDVEQQEEEDNDEEAA 150
           R+    +E +  L +    P  P+ +P    +G   +R G G     +QQ  +D +EEAA
Sbjct: 13  RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72

Query: 151 AGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAE---------SGAGGGRRATISSP 200
           A   A +    R QD       + A   +G               +G  G RR + SSP
Sbjct: 73  AAPAADQ---QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSP 128



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 39/159 (24%), Positives = 56/159 (35%), Gaps = 37/159 (23%)

Query: 29  PGRTSSEPPAGLRVSGEEETENVGGAN--RHPRTSPKTSSCGVVHRPEREALENEPGPQG 86
           P  TSS      R   + +    GG    R   +SP     G   R E  A    P  +G
Sbjct: 93  PAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRG 152

Query: 87  --------------TLSGAGSRRGA---PGAEHEPSLSSRHKN---PAP----------- 115
                           +G G RRG+   P A+ + +     +    P P           
Sbjct: 153 HRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRK 212

Query: 116 ---PEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAA 151
              P+ +P++G   RRG        +QQ  +D +EEAAA
Sbjct: 213 RQQPQCRPAAGTGQRRGS-RSSPSADQQRAQDREEEAAA 250


>gi|169215850 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 547

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 54/211 (25%), Positives = 73/211 (34%), Gaps = 36/211 (17%)

Query: 58  PRTSPKTSSCGVVHRPEREALENEP----GPQGTLSGAGSRRGAPG--------AEHEPS 105
           PR SP  S+     R  R +   EP     P G  + A +R   PG         E    
Sbjct: 213 PRGSPHNSAGPRTPRLARASPPGEPFMRVAPPGLAAAAAARDSEPGPVPGAGGCGEDRLG 272

Query: 106 LSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQD 165
              R +N  P   + +SGR  RRG   GG++                SR     S    D
Sbjct: 273 SQPRPENGPPGSHRTASGRGLRRGDSEGGVN-----------RGIGPSRV----SLLAPD 317

Query: 166 SRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKI 225
            + L+            GSA  G   G R      L L+   +++             + 
Sbjct: 318 KKRLNNAPR--------GSAAPGPPRGPRLQGGGSLTLQPDYAKYATFKAAALKAAVPRA 369

Query: 226 RLSGAPPPPPSAPA-RPCPAPAPTPTPAIPP 255
           R S    P PS P  RP PA +P+ +PA  P
Sbjct: 370 RRSANRLPRPSGPRPRPAPARSPSQSPAGTP 400


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 62/241 (25%), Positives = 81/241 (33%), Gaps = 40/241 (16%)

Query: 27  GGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQG 86
           G PG     PPAG    G       GG  R    SP+     V   P   A +  P P+G
Sbjct: 81  GAPGAAPEPPPAGRARPGG------GGPQRPGPPSPRRPL--VPAGPAPPAAKLRPPPEG 132

Query: 87  TLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDND 146
           +   AGS    P A      +     PA P           R GPG G            
Sbjct: 133 S---AGSCAPVPAAA--AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPG 187

Query: 147 EEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELE-G 205
           + A  G+            +++L+G +       ++  A S    G  A +  P     G
Sbjct: 188 KPAGPGA------------AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG 235

Query: 206 TVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPPIDPEVLRDLE 265
           TV             +Q    +  A PP P+AP+ P  APAP    A PP  P     L 
Sbjct: 236 TV-------------IQTPPFVGAAAPPAPAAPSPPA-APAPAAPAAAPPPPPPAPATLA 281

Query: 266 R 266
           R
Sbjct: 282 R 282


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 64/261 (24%), Positives = 85/261 (32%), Gaps = 44/261 (16%)

Query: 6   GRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTS 65
           G PG   DL  V         G  G   S  P G +  GE+    + G +          
Sbjct: 284 GDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYK--GEKGKRGIDGVDGVKGEMGYPG 341

Query: 66  SCGVVHRPEREALENEPGPQGTLSGAGSR--RGAPGAEHEPSLSSRHKNPAPPEGKPSSG 123
             G    P  + ++  PGP+G     G +  +G PGA+ E         P+  EG+P   
Sbjct: 342 LPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGS-SGPSGDEGQP--- 397

Query: 124 RDCRRGGPGG-GMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSS 182
                G PG  G   E  +E +   + A G R G          R   G     G  G  
Sbjct: 398 -----GEPGPPGEKGEAGDEGNPGPDGAPGERGGPG-------ERGPRGTPGTRGPRGDP 445

Query: 183 GSAESGAGGGRRATISSPLEL--EGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPAR 240
           G A      GR   +  P +    G +   G                 G   PP S  AR
Sbjct: 446 GEAGPQGDQGREGPVGVPGDPGEAGPIGPKG---------------YRGDEGPPGSEGAR 490

Query: 241 PCPAPAPTPTPAIPPIDPEVL 261
             P PA       PP DP ++
Sbjct: 491 GAPGPAG------PPGDPGLM 505


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 57/295 (19%), Positives = 97/295 (32%), Gaps = 49/295 (16%)

Query: 7    RPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLR----VSGEEETENVGGANRHPRTSP 62
            RPG E +LL   +H+ +     P    ++    LR      G +E +++     +P  + 
Sbjct: 2453 RPGEEAELLVKLDHEGVT---SPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAG 2509

Query: 63   KTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAP-------GAEHEPSLSSRHKNPAP 115
             +       +     L  EPGP  T   +G+ +          GAE   S SS     + 
Sbjct: 2510 SSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSS 2569

Query: 116  PEGKPSS----------------------GRDCRRGGPGGGMDVEQQEEEDNDEEAAAGS 153
                 SS                      GR+C                  +   +++ S
Sbjct: 2570 SSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSS 2629

Query: 154  RAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDL 213
             +  S SS    S S    S +   + SS S+ S +     ++ SS  + + + S   + 
Sbjct: 2630 SSSSSSSSSSSSSSS----SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEA 2685

Query: 214  THFVANNLQLKIRL-------SGAPPPPPSAPARPCPAPAPTPTPAIP--PIDPE 259
                      +  L       +G   P   +P +  PAP P   P  P  P+ P+
Sbjct: 2686 APAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPK 2740



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 47/199 (23%), Positives = 67/199 (33%), Gaps = 55/199 (27%)

Query: 96  GAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRG-------------------------- 129
           GAPG+ H  + S+R        G P+ G   R G                          
Sbjct: 171 GAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGE 230

Query: 130 ---GPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDG------LSEACGGAG 180
              GP G +D+ Q+   +  ++      A R  S  L +S++ +       L+   GGAG
Sbjct: 231 EASGPRGVVDLTQEARAEGRQDRGPPRLAER-LSPFLAESKTKNAALQPSVLTMCNGGAG 289

Query: 181 SSGS----AESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPS 236
             G     AE+G GG + A            +R  +    +     L   L G  P P  
Sbjct: 290 DVGLPALVAEAGRGGAKEA------------ARQDEGARLLRRTETL---LPGPRPCPSP 334

Query: 237 APARPCPAPAPTPTPAIPP 255
            P  P P   P   PA  P
Sbjct: 335 LPPPPAPPKGPPAPPAATP 353



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 8/61 (13%)

Query: 229  GAPPPPPSAPARPCPAPAPTPTPAIPPIDPEVLRDLERLSRELGGRVDRLLRGLGGAVQE 288
            GA  PPP APA P  A AP  +         +       ++  G  V +  RG GGAV +
Sbjct: 2059 GAGLPPPRAPALPSEARAPHAS--------SLTAAKRSKAKAKGKEVKKENRGKGGAVSK 2110

Query: 289  L 289
            L
Sbjct: 2111 L 2111


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 68/253 (26%), Positives = 91/253 (35%), Gaps = 27/253 (10%)

Query: 27   GGPGRTSSE----PPAGLRVS--GEEETENVGGANRHPRTSPKTSSCGVVHRPEREA--- 77
            GGP   S +    PPA    S  G   T +  GA   P  +P +   G+   P + A   
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128

Query: 78   -LENEPGPQGTLSGAGSRRGAPG--AEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGG 134
                 P P+G L+     +GAP   A   PS       P PP+G P++        P GG
Sbjct: 1129 PAATPPSPKGGLA-TPPPKGAPTTPAATPPSPKGGLATP-PPKGAPTTPA-ATPPSPKGG 1185

Query: 135  MDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRR 194
            +     +       A   S  G   +   + + +    +      G +  +  GA     
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245

Query: 195  ATISSPLELEGTVSRHGDLTHFVANNLQLKIRLS-----GAPPP----PPSAPARPCPAP 245
            AT  SP     T    G  T   A    LK  L+     GAP P    PPS    P  +P
Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305

Query: 246  ---APTPTPAIPP 255
               APTP  A PP
Sbjct: 1306 PKGAPTPPAATPP 1318



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 58/239 (24%), Positives = 83/239 (34%), Gaps = 24/239 (10%)

Query: 27   GGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREA----LENEP 82
            G P   ++ PP+     G   T    GA   P  +P +   G+   P + A        P
Sbjct: 1124 GAPTTPAATPPSP---KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180

Query: 83   GPQGTLSGAGSRRGAPG--AEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQ 140
             P+G L+   S +GAP   A   PS       P+P +G P++        P GG+     
Sbjct: 1181 SPKGGLA-TPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPA-ATPPSPKGGLATPSP 1237

Query: 141  EEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSP 200
            +       A   S  G   +   + + +    +      G +     GA      T  SP
Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297

Query: 201  LELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPPIDPE 259
                 T    G  T   A            PP P  +P  P P  APTP PA+ P  P+
Sbjct: 1298 KGGPATSPPKGAPTPPAAT-----------PPSPKGSPGTPPPKGAPTP-PAVTPPSPK 1344



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 14/28 (50%), Positives = 15/28 (53%)

Query: 228 SGAPPPPPSAPARPCPAPAPTPTPAIPP 255
           +  PP P   PA P P  APTP  A PP
Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPP 994



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 7/60 (11%)

Query: 230  APPPP---PSAPARPCPAPAPTPTPAIPPIDPEVLRDL----ERLSRELGGRVDRLLRGL 282
            AP PP   P +P +    PAP  TP  PP+ P  L+D       ++ ++G  V +  +GL
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 14/28 (50%), Positives = 15/28 (53%)

Query: 228 SGAPPPPPSAPARPCPAPAPTPTPAIPP 255
           +  PP P   PA P P  APTP  A PP
Sbjct: 944 AATPPSPKGGPATPSPKWAPTPPAATPP 971



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 15/32 (46%), Positives = 18/32 (56%), Gaps = 1/32 (3%)

Query: 228  SGAPPPPPSAPARPCPAPAPTPTPAIPPIDPE 259
            +  PP P   PA P P  APTP PA+ P  P+
Sbjct: 990  AATPPSPKGGPATPSPKGAPTP-PAVTPPSPK 1020



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 14/26 (53%), Positives = 14/26 (53%)

Query: 230 APPPPPSAPARPCPAPAPTPTPAIPP 255
           A P P   PA P P  APTP  A PP
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPP 948



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 48/183 (26%), Positives = 69/183 (37%), Gaps = 23/183 (12%)

Query: 82  PGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPA--PPEGKPSSGRDCRRGGPGGGMDVEQ 139
           P PQ T +   +   AP  E   S+ S    PA  PP  K   G              ++
Sbjct: 712 PSPQNTCAPLATLVLAP--EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE 769

Query: 140 QEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLS---EACGGAGSSGSAESGAGGGRRAT 196
              ED+   A A S+   ++   L DS S  G+S   +        GSA      G  ++
Sbjct: 770 CPTEDSGASATASSKGTLTY---LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826

Query: 197 ISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPPI 256
             SP+E             F+  N  L  + S   P    +P  P P  APTP+ A+ P+
Sbjct: 827 PVSPVEAS-----------FLPEN-SLSFQGSKDSPATTHSPTPPSPKGAPTPS-AVTPL 873

Query: 257 DPE 259
            P+
Sbjct: 874 SPK 876



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 5/35 (14%)

Query: 229  GAPPPP----PSAPARPCPAPAPTPTPAIPPIDPE 259
            GAP P     P A   P P  APTP PA+ P  PE
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTP-PAVTPPSPE 1625



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 17/45 (37%), Positives = 21/45 (46%), Gaps = 2/45 (4%)

Query: 227  LSGAPPPPPSAPARPCPAPAPTPTPAIPPIDPEVLRDLERLSREL 271
            +S AP PP S P  P P P   P     P  P ++  LE  S+ L
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLV--LESPSKPL 1832



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 13/30 (43%), Positives = 15/30 (50%)

Query: 229  GAPPPPPSAPARPCPAPAPTPTPAIPPIDP 258
            GA  PP + P  P  +PA TP P   P  P
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPTTP 1060



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 1/29 (3%)

Query: 231  PPPPPSAPARPCPAPAPTPTPAIPPIDPE 259
            PP P   PA P P   PT +PA+ P+ P+
Sbjct: 1386 PPSPKRGPAIPSPKGDPT-SPAVIPLSPK 1413



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 12/23 (52%), Positives = 13/23 (56%)

Query: 229  GAPPPPPSAPARPCPAPAPTPTP 251
            GAP PP   P  P  +PA TP P
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFP 1029


>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
          Length = 417

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 71/277 (25%), Positives = 99/277 (35%), Gaps = 60/277 (21%)

Query: 26  GGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPE---REALENEP 82
           G G  R S   P+  +   ++  E    A       P  +S G  HR E   R+  +  P
Sbjct: 117 GTGQRRGSRSSPSADQQRAQDREEEAAAA-------PVPTSRG--HRTEKRKRQQPQRRP 167

Query: 83  -GPQGTLSGAGS-----RRGAPGAEHE----PSLSSR-----HKNPAPPEGKPSSGRDCR 127
            G  G   G+GS     ++GA   E E    P+ +SR      + P  P+ +P+ G   R
Sbjct: 168 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQR 227

Query: 128 RGGPGGGMDVEQQEEEDNDEEAAAG----SRAGRSFSSRLQ--DSRSLDGLSEACGGAGS 181
           RG        +QQ  +D +EEAAA     SR  R+   + Q    R   G  +  G   S
Sbjct: 228 RGS-RSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYS 286

Query: 182 SGSAESGA--------------GGGRRATISSPLELE-----GTVSRHGDLTHFVANNLQ 222
             + + GA                G R      L+L+     GT  R G      AN   
Sbjct: 287 PSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQ-- 344

Query: 223 LKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPPIDPE 259
                 GA      A A P P  +   T    P  P+
Sbjct: 345 -----QGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQ 376



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 28/141 (19%)

Query: 26  GGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREA---LENEP 82
           G G  R S   P+  +   ++  E    A       P  +S G  HR E+     L+ +P
Sbjct: 276 GTGQRRGSGYSPSADQQGAQDREEEAAAA-------PAPTSSG--HRTEKRKRLQLQCQP 326

Query: 83  -GPQGTLSGAG-----SRRGAPGAEHEPSL-----SSRHKN----PAPPEGKPSSGRDCR 127
            G  G   G+G     +++GA   E E +      SS H+     P  P+ +P++G   R
Sbjct: 327 AGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQR 386

Query: 128 RGGPGGGMDVEQQEEEDNDEE 148
           RG  G     +QQ  +D +EE
Sbjct: 387 RGS-GSSPSADQQRAQDREEE 406



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 46/164 (28%), Positives = 63/164 (38%), Gaps = 17/164 (10%)

Query: 34  SEPPAGLRVSGEEETENVGGAN--RHPRTSPKTSSCGVVHRPEREALENEPGPQGTLSGA 91
           +E    LR   + + +  GG    R   +SP     G   R E  A      P      A
Sbjct: 27  NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA----APAADQQRA 82

Query: 92  GSRRGAPGAEHEPSLSSRHKNPAPP----EGKPSSGRDCRRGGPGGGMDVEQQEEEDNDE 147
             R     A   P+ SS H+         + +P+ G   RRG        +QQ  +D +E
Sbjct: 83  QDREEEAAAAPVPT-SSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSP-SADQQRAQDREE 140

Query: 148 EAAAG----SRAGRSFS-SRLQDSRSLDGLSEACGGAGSSGSAE 186
           EAAA     SR  R+    R Q  R   G +    G+GSS SA+
Sbjct: 141 EAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSAD 184



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 9/116 (7%)

Query: 94  RRGAPGAEHEPSLSSRHKNPAPPEGKPS---SGRDCRRGGPGGGMDVEQQEEEDNDEEAA 150
           R+    +E +  L +    P  P+ +P    +G   +R G G     +QQ  +D +EEAA
Sbjct: 13  RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72

Query: 151 AGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGS------AESGAGGGRRATISSP 200
           A   A +  +   ++  +   +  + G               +G  G RR + SSP
Sbjct: 73  AAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSP 128


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 62/261 (23%), Positives = 94/261 (36%), Gaps = 44/261 (16%)

Query: 138  EQQEEEDNDEEAAAGS--RAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRA 195
            EQ+ E    E    GS   A  +   +L  +R L+   EA     +       A  GR  
Sbjct: 1354 EQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQ 1413

Query: 196  TISSPL-----ELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPA------ 244
             + + L     +     ++ G L   +   L L    S AP P P +PAR  PA      
Sbjct: 1414 GLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSPARDAPAEGSGEG 1473

Query: 245  -----------------PAPTPTPAIPPIDPEV-----------LRDLERLSRELGGRVD 276
                             P P  +PA P +DPE            LR  +R   EL  +  
Sbjct: 1474 LNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERDELRTQTS 1533

Query: 277  RLLRGLGGAVQELTALSVGCIQTYRDAVDS--LGEAVDMSIKGMYTLLARCEE-LERALQ 333
             L R L     E  + +    Q  +   +S     +VD  + G+   LA  EE + R+ +
Sbjct: 1534 ALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSER 1593

Query: 334  PVQGLARQVRDIRRTLEVLEA 354
              +    QV  + R+L+  E+
Sbjct: 1594 ERRATLDQVATLERSLQATES 1614


>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
          Length = 1865

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 9/70 (12%)

Query: 187  SGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAP-ARPCPAP 245
            +G  G   A +  PL L+G+V+ +G        NL     L G+P PPP  P  R  P P
Sbjct: 1788 NGMTGADVADVPPPLPLKGSVADYG--------NLMENQDLLGSPTPPPPPPHQRHLPPP 1839

Query: 246  APTPTPAIPP 255
             P+ TP  PP
Sbjct: 1840 LPSKTPPPPP 1849


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 46/164 (28%), Positives = 65/164 (39%), Gaps = 15/164 (9%)

Query: 136  DVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDG-----LSEACGGAGSSGSAES--- 187
            D E+ EE+D+D+E   G   G       + + S DG       +A GG G+    E+   
Sbjct: 1964 DYEEDEEDDDDDEDDTG--MGDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEES 2021

Query: 188  -GAGGGRRATISSPLELEG-TVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAP 245
             G G G      S    EG T +     +  V+   Q         P  P +P RP    
Sbjct: 2022 MGGGEGNHRAADSQNSGEGNTGAAESSFSQEVSREQQPSSASERQAPRAPQSPRRPPHPL 2081

Query: 246  APTPTPAIPP--IDPEVLRDLERLSRELGGRVDRLLRGLGGAVQ 287
             P  T   PP  + P V R ++   R+  GR  +L  G+GG  Q
Sbjct: 2082 PPRLTIHAPPQELGPPVQR-IQMTRRQSVGRGLQLTPGIGGMQQ 2124


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 60/241 (24%), Positives = 89/241 (36%), Gaps = 20/241 (8%)

Query: 29  PGRTS--SEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREA--LENEPGP 84
           PGR S    P  G    G + ++   G     R  P+         P+R+   L+  P P
Sbjct: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487

Query: 85  QGT--LSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCR----RGGPGGGMDVE 138
           QG   LSG G   G+P  +  PS +S  + PA     P+ G+  +     GGP G     
Sbjct: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP-GAPPAA 546

Query: 139 QQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAE---SGAGGGRRA 195
           +     + +  A   +A R  S          G     GG    G  +     AG  R+A
Sbjct: 547 RPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP--GGQQRQGPPQKPPGPAGPTRQA 604

Query: 196 TISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAP----PPPPSAPARPCPAPAPTPTP 251
           + + P+   G  +             + K +L+  P    PPP +A A   P P    +P
Sbjct: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASP 664

Query: 252 A 252
           A
Sbjct: 665 A 665


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.132    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,625,529
Number of Sequences: 37866
Number of extensions: 1237994
Number of successful extensions: 24096
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 534
Number of HSP's successfully gapped in prelim test: 944
Number of HSP's that attempted gapping in prelim test: 13051
Number of HSP's gapped (non-prelim): 8860
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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