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Search of human proteins with 190341065
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190341065 CP110 protein [Homo sapiens]
(991 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190341065 CP110 protein [Homo sapiens] 1947 0.0
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 46 2e-04
gi|41352705 kinesin family member 3C [Homo sapiens] 46 2e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 45 3e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 45 3e-04
gi|70980531 GGA binding partner [Homo sapiens] 45 3e-04
gi|16262452 cingulin [Homo sapiens] 45 4e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 43 0.001
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 43 0.001
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 43 0.002
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 43 0.002
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 43 0.002
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 43 0.002
gi|38327558 guanylate binding protein 2, interferon-inducible [H... 42 0.002
gi|42794779 myosin 18A isoform b [Homo sapiens] 42 0.004
gi|28416946 myosin 18A isoform a [Homo sapiens] 42 0.004
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 42 0.004
gi|118498368 kinectin 1 isoform c [Homo sapiens] 41 0.005
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 41 0.005
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 41 0.005
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 41 0.005
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 41 0.005
gi|45237195 Janus kinase and microtubule interacting protein 2 [... 41 0.005
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 41 0.005
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 41 0.006
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 41 0.006
gi|71061468 centromere protein E [Homo sapiens] 40 0.008
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens] 40 0.008
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 40 0.008
gi|15208660 tripartite motif protein 21 [Homo sapiens] 40 0.011
>gi|190341065 CP110 protein [Homo sapiens]
Length = 991
Score = 1947 bits (5043), Expect = 0.0
Identities = 991/991 (100%), Positives = 991/991 (100%)
Query: 1 MEEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEK 60
MEEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEK
Sbjct: 1 MEEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEK 60
Query: 61 QKALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVP 120
QKALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVP
Sbjct: 61 QKALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVP 120
Query: 121 ATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLARDSEGFNSPKQCDSSNIS 180
ATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLARDSEGFNSPKQCDSSNIS
Sbjct: 121 ATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLARDSEGFNSPKQCDSSNIS 180
Query: 181 HVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSLQNLMKKSKEYIE 240
HVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSLQNLMKKSKEYIE
Sbjct: 181 HVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSLQNLMKKSKEYIE 240
Query: 241 REQSRRSLRGSMNRIVNESHLDKEHDAVEVADCVKEKGQLTGKHCVSVIPDKPSLNKSNV 300
REQSRRSLRGSMNRIVNESHLDKEHDAVEVADCVKEKGQLTGKHCVSVIPDKPSLNKSNV
Sbjct: 241 REQSRRSLRGSMNRIVNESHLDKEHDAVEVADCVKEKGQLTGKHCVSVIPDKPSLNKSNV 300
Query: 301 LLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLTGS 360
LLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLTGS
Sbjct: 301 LLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLTGS 360
Query: 361 YAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDENTN 420
YAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDENTN
Sbjct: 361 YAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDENTN 420
Query: 421 VPEIMPKLPTDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTV 480
VPEIMPKLPTDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTV
Sbjct: 421 VPEIMPKLPTDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTV 480
Query: 481 EGQLTSDERGAHIMNSTCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKNCSLQTE 540
EGQLTSDERGAHIMNSTCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKNCSLQTE
Sbjct: 481 EGQLTSDERGAHIMNSTCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKNCSLQTE 540
Query: 541 LNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENC 600
LNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENC
Sbjct: 541 LNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENC 600
Query: 601 PYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLE 660
PYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLE
Sbjct: 601 PYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLE 660
Query: 661 EQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISD 720
EQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISD
Sbjct: 661 EQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISD 720
Query: 721 SSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPF 780
SSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPF
Sbjct: 721 SSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPF 780
Query: 781 GRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSE 840
GRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSE
Sbjct: 781 GRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSE 840
Query: 841 APLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQ 900
APLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQ
Sbjct: 841 APLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQ 900
Query: 901 MDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVH 960
MDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVH
Sbjct: 901 MDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVH 960
Query: 961 RLLSRQGSICRKNPKKAAKCCDNLRRQHSLG 991
RLLSRQGSICRKNPKKAAKCCDNLRRQHSLG
Sbjct: 961 RLLSRQGSICRKNPKKAAKCCDNLRRQHSLG 991
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/216 (22%), Positives = 98/216 (45%), Gaps = 12/216 (5%)
Query: 554 LMQNQNTRQQMDTPMVSCGNE-QFLDNSFEKVKRRL-DLDIDGLQKENCPYVITSGIT-- 609
L + + T+ + D + + E + L EK K + DL+ Q+ N + + +
Sbjct: 1341 LEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGK 1400
Query: 610 ----EQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQ 665
+ E Q +K ++ + ML T +KE+E + +M + E R+R +Q
Sbjct: 1401 LTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQ-N 1459
Query: 666 QLSLLIAEQEREQERLQKEIEEQEKMLK--EKKAMTAEASELDINNAVELEWRKISDSSL 723
++ +L A+ + LQK EE+++++ E + +S + +N +E R IS++S
Sbjct: 1460 EMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSK 1519
Query: 724 LETMLSQADSLHTSNSNSSGFTNSAMQYSF-VSANE 758
+ET + S+++ + SF +S N+
Sbjct: 1520 IETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNK 1555
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 45.8 bits (107), Expect = 2e-04
Identities = 41/170 (24%), Positives = 80/170 (47%), Gaps = 26/170 (15%)
Query: 557 NQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHL 616
+ N + P++ E+ ++N ++ K RL+ + +Q + + +E+Q L
Sbjct: 437 DNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDR-------SLVSEEKQKL 489
Query: 617 PEKRYPKGSGFVNKNKMLGTSSKESE--ELLKSKMLAFEEM-----RKRLEEQHAQQLSL 669
E+ K KML +E + ELL +K A E R ++ + QQ L
Sbjct: 490 LEE----------KEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKML 539
Query: 670 LIAEQE-REQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKI 718
+ QE EQ+R ++E++ QE ML++++ M + + VE++ +K+
Sbjct: 540 ELKRQEIAEQKRREREMQ-QEMMLRDEETMELRGTYTSLQQEVEVKTKKL 588
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/225 (24%), Positives = 97/225 (43%), Gaps = 29/225 (12%)
Query: 531 LEKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDL 590
+E N S ++ K + +++N+ +++ S N Q L K K +L+
Sbjct: 486 VEGNASKILKMEKENQRLSKKVEILENEIVQEKQ-----SLQNCQNLSKDLMKEKAQLEK 540
Query: 591 DIDGLQKENCPYVITSGITEQERQHLPE-----------KRYPKGSGFVNKNKMLGTSSK 639
I+ L +EN I I EQE +HL + + +NK+L S K
Sbjct: 541 TIETL-RENSERQIK--ILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIK 597
Query: 640 ESEELLKSKMLAFEEMRKRLEE-----QHAQQLSLLIAEQEREQERLQKEIEEQEKMLKE 694
E+ L +++K LE + A++L + E+E E LQK+I + ++
Sbjct: 598 ETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEK 657
Query: 695 KKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNS 739
+A+ E SEL+ N + +K DS + + Q +SL NS
Sbjct: 658 IEALEQENSELERENR---KLKKTLDS--FKNLTFQLESLEKENS 697
Score = 35.4 bits (80), Expect = 0.27
Identities = 156/809 (19%), Positives = 304/809 (37%), Gaps = 141/809 (17%)
Query: 3 EYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEKQK 62
E+ K + L + L T++ L Q E G S L+ E KE Q K K
Sbjct: 340 EFYKARVEELKEDNQVLLETKTMLEDQLE--------GTRARSDKLH-ELEKENLQLKAK 390
Query: 63 ALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQ-----WEMETVYSNSEVRNL 117
D+E + ++RKK ++E+++ + D+ WE+E + SE+
Sbjct: 391 LHDMEMERDMDRKK-----IEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEA 445
Query: 118 NVPATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKT-DGIDLARDSEGFNSPK---- 172
S T+++L K L ++N+ KT + + DS N+ K
Sbjct: 446 P-----QKSLGHEVNELTSSRLLK----LEMENQSLTKTVEELRTTVDSVEGNASKILKM 496
Query: 173 ----QCDSSNISHVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSL 228
Q S + +ENE + S + L D + E+ L E + + +
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD---LMKEKAQLEKTIETLRENSERQI 553
Query: 229 QNLMKKSKEYIEREQSRRSLRGSMNRIVNESHLDKE----HDAV-----EVADCVKEKGQ 279
+ ++++ E++ + S R ++ ++KE H+++ +++ EK Q
Sbjct: 554 K-ILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQ 612
Query: 280 L---------TGKHCVSVIPDKPSLNKSNVLLQGASTQASSMSMPVLASFSKVDIPIRTG 330
+ G+ + + L K N LLQ T + + K++ +
Sbjct: 613 IKKELEHYKEKGERAEELENELHHLEKENELLQKKITN-------LKITCEKIEALEQEN 665
Query: 331 HPTVLESNSDFKVIPTFVTENNVIKSLTGSYAKLPSPEPSMSPKMHRRRSRTSSACHILI 390
E+ K + +F ++SL ++L + + + + + +
Sbjct: 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQL 725
Query: 391 NNP--INACELSPKGKE----------------QAMDL---IIQDTDENTNVPEIMPKLP 429
N + E KG E Q +D+ +Q T EN+N + + +L
Sbjct: 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN--KKIQQLE 783
Query: 430 TDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTVEGQLTSDER 489
++L + + KN E+K + K + + LE + + QL D++
Sbjct: 784 SELQDLEMENQTLQKNLEELK---ISSKRLEQLEKENKSLEQETS--------QLEKDKK 832
Query: 490 GAHIMNSTCAAMPKLHEPYASSQCIASPNF----GTVSGLKPASMLEKNCSLQTELNKSY 545
N ++ + + N T+S K + +++C EL K
Sbjct: 833 QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLS--KEIGIYKESCVRLKELEKEN 890
Query: 546 D--VKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENCPYV 603
VK + + R+ + + + Q ++N EK+ +L+ GL KE +
Sbjct: 891 KELVKRATIDIKTLVTLREDLVSEKL---KTQQMNNDLEKLTH--ELEKIGLNKERLLHD 945
Query: 604 ITSGITEQERQHLPEKRYP---KGSGFVNKNKMLGTSSKESE---------ELLKSKMLA 651
S T+ R L E + K S + + K+ ++ E + LK+
Sbjct: 946 EQS--TDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKN 1003
Query: 652 FEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAV 711
+E +++R +E+ Q S I+ ++ + ER +E + +LK K + E++ NNA
Sbjct: 1004 YEALKQRQDEERMVQSSPPISGEDNKWERESQETTRE--LLKVKDRLI----EVERNNAT 1057
Query: 712 ELEWRKISDSSLLETMLSQADSLHTSNSN 740
++ L+T L Q L T N+N
Sbjct: 1058 -----LQAEKQALKTQLKQ---LETQNNN 1078
Score = 33.9 bits (76), Expect = 0.78
Identities = 61/280 (21%), Positives = 115/280 (41%), Gaps = 48/280 (17%)
Query: 574 EQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKM 633
++ L+NS +K+++ L+ ++ L+ EN + + E + + KR + +NK
Sbjct: 769 QKTLENSNKKIQQ-LESELQDLEMEN--QTLQKNLEELK---ISSKRLEQ---LEKENKS 819
Query: 634 LGTSSKESEELLKSKMLAFEEMRKRLEEQHA------QQLSLLIAEQEREQERLQKEI-- 685
L +E+ +L K K E+ KRL +Q ++ ++ I E+E + L KEI
Sbjct: 820 L---EQETSQLEKDKK-QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGI 875
Query: 686 -----EEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSN 740
+++ KE K + A+ +DI V L +S+ + M + + L T
Sbjct: 876 YKESCVRLKELEKENKELVKRAT-IDIKTLVTLREDLVSEKLKTQQMNNDLEKL-THELE 933
Query: 741 SSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFN 800
G + + S +++ + L S K S ++ K
Sbjct: 934 KIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKS-------------------LEIKEE 974
Query: 801 KITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSE 840
KI A+ + L +L+Q +TVK E ++ Q E
Sbjct: 975 KIAAL-EARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1013
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/225 (24%), Positives = 97/225 (43%), Gaps = 29/225 (12%)
Query: 531 LEKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDL 590
+E N S ++ K + +++N+ +++ S N Q L K K +L+
Sbjct: 486 VEGNASKILKMEKENQRLSKKVEILENEIVQEKQ-----SLQNCQNLSKDLMKEKAQLEK 540
Query: 591 DIDGLQKENCPYVITSGITEQERQHLPE-----------KRYPKGSGFVNKNKMLGTSSK 639
I+ L +EN I I EQE +HL + + +NK+L S K
Sbjct: 541 TIETL-RENSERQIK--ILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIK 597
Query: 640 ESEELLKSKMLAFEEMRKRLEE-----QHAQQLSLLIAEQEREQERLQKEIEEQEKMLKE 694
E+ L +++K LE + A++L + E+E E LQK+I + ++
Sbjct: 598 ETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEK 657
Query: 695 KKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNS 739
+A+ E SEL+ N + +K DS + + Q +SL NS
Sbjct: 658 IEALEQENSELERENR---KLKKTLDS--FKNLTFQLESLEKENS 697
Score = 33.9 bits (76), Expect = 0.78
Identities = 150/807 (18%), Positives = 300/807 (37%), Gaps = 138/807 (17%)
Query: 3 EYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEKQK 62
E+ K + L + L T++ L Q E G S L+ E KE Q K K
Sbjct: 340 EFYKARVEELKEDNQVLLETKTMLEDQLE--------GTRARSDKLH-ELEKENLQLKAK 390
Query: 63 ALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQ-----WEMETVYSNSEVRNL 117
D+E + ++RKK ++E+++ + D+ WE+E + SE+
Sbjct: 391 LHDMEMERDMDRKK-----IEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEA 445
Query: 118 NVPATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKT-DGIDLARDSEGFNSPK---- 172
S T+++L K L ++N+ KT + + DS N+ K
Sbjct: 446 P-----QKSLGHEVNELTSSRLLK----LEMENQSLTKTVEELRTTVDSVEGNASKILKM 496
Query: 173 ----QCDSSNISHVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSL 228
Q S + +ENE + S + L D + E+ L E + + +
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD---LMKEKAQLEKTIETLRENSERQI 553
Query: 229 QNLMKKSKEYIEREQSRRSLRGSMNRIVNESHLDKE----HDAV-----EVADCVKEKGQ 279
+ ++++ E++ + S R ++ ++KE H+++ +++ EK Q
Sbjct: 554 K-ILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQ 612
Query: 280 L---------TGKHCVSVIPDKPSLNKSNVLLQGASTQASSMSMPVLASFSKVDIPIRTG 330
+ G+ + + L K N LLQ T + + K++ +
Sbjct: 613 IKKELEHYKEKGERAEELENELHHLEKENELLQKKITN-------LKITCEKIEALEQEN 665
Query: 331 HPTVLESNSDFKVIPTFVTENNVIKSLTGSYAKLPSPEPSMSPKMHRRRSRTSSACHILI 390
E+ K + +F ++SL ++L + + + + + +
Sbjct: 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQL 725
Query: 391 NNP--INACELSPKGKE----------------QAMDL---IIQDTDENTNVPEIMPKLP 429
N + E KG E Q +D+ +Q T EN+N + + +L
Sbjct: 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN--KKIQQLE 783
Query: 430 TDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTVEGQLTSDER 489
++L + + KN E+K + K + + LE + + QL D++
Sbjct: 784 SELQDLEMENQTLQKNLEELK---ISSKRLEQLEKENKSLEQETS--------QLEKDKK 832
Query: 490 GAHIMNSTCAAMPKLHEPYASSQCIASPNF----GTVSGLKPASMLEKNCSLQTELNK-- 543
N ++ + + N T+S K + +++C EL K
Sbjct: 833 QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLS--KEIGIYKESCVRLKELEKEN 890
Query: 544 -------SYDVKNPSPL---LMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDID 593
+ D+K L L+ + QQM+ + + L + EK+ + +
Sbjct: 891 KELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL------EKLTHELEKIGLNKERLLH 944
Query: 594 GLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFE 653
Q + Y + E + E + K + + + +++ + LK+ +E
Sbjct: 945 DEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYE 1004
Query: 654 EMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVEL 713
+++R +E+ Q S I+ ++ + ER +E + +LK K + E++ NNA
Sbjct: 1005 ALKQRQDEERMVQSSPPISGEDNKWERESQETTRE--LLKVKDRLI----EVERNNAT-- 1056
Query: 714 EWRKISDSSLLETMLSQADSLHTSNSN 740
++ L+T L Q L T N+N
Sbjct: 1057 ---LQAEKQALKTQLKQ---LETQNNN 1077
Score = 31.6 bits (70), Expect = 3.9
Identities = 65/280 (23%), Positives = 115/280 (41%), Gaps = 49/280 (17%)
Query: 574 EQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKM 633
++ L+NS +K+++ L+ ++ L+ EN + + E + + KR + +NK
Sbjct: 769 QKTLENSNKKIQQ-LESELQDLEMEN--QTLQKNLEELK---ISSKRLEQ---LEKENKS 819
Query: 634 LGTSSKESEELLKSKMLAFEEMRKRLEEQHA------QQLSLLIAEQEREQERLQKEI-- 685
L +E+ +L K K E+ KRL +Q ++ ++ I E+E + L KEI
Sbjct: 820 L---EQETSQLEKDKK-QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGI 875
Query: 686 -----EEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSN 740
+++ KE K + A+ +DI V L +S+ + M + + L T
Sbjct: 876 YKESCVRLKELEKENKELVKRAT-IDIKTLVTLREDLVSEKLKTQQMNNDLEKL-THELE 933
Query: 741 SSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFN 800
G + + S ++ L S L K SLEI K
Sbjct: 934 KIGLNKERLLHDEQSTDDRYKLLESKLESTLKK------------------SLEI--KEE 973
Query: 801 KITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSE 840
KI A+ + L +L+Q +TVK E ++ Q E
Sbjct: 974 KIAAL-EARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
>gi|70980531 GGA binding partner [Homo sapiens]
Length = 441
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/163 (23%), Positives = 81/163 (49%), Gaps = 16/163 (9%)
Query: 574 EQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQE--RQHLPEKRYPKGSGFVNKN 631
E+ L+ +++ LD + + L+++ +I ++E + L E+R NK
Sbjct: 248 EELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQR------NKE 301
Query: 632 KMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKM 691
++ + E E + + + EE RK LE+ HA++ L E ++QE++ +EI +K
Sbjct: 302 ALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEI---QKA 358
Query: 692 LKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSL 734
++E++ ++ E + A +E +K S+ ++ E + D L
Sbjct: 359 IQEQRKISQETVK-----AAIIEEQKRSEKAVEEAVKRTRDEL 396
Score = 32.0 bits (71), Expect = 3.0
Identities = 26/126 (20%), Positives = 59/126 (46%), Gaps = 10/126 (7%)
Query: 595 LQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEE 654
LQ++ I ++E+E+Q + + + K+ +L + +E + ++F++
Sbjct: 134 LQQKISSLEIKLKVSEEEKQRIKQDV----ESLMEKHNVLEKGFLKEKE---QEAISFQD 186
Query: 655 MRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELE 714
K L+E+H Q+L + ++ E L ++E + +L+ EA E +A+E +
Sbjct: 187 RYKELQEKHKQELEDM---RKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQ 243
Query: 715 WRKISD 720
K +
Sbjct: 244 AHKCEE 249
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 44.7 bits (104), Expect = 4e-04
Identities = 51/212 (24%), Positives = 100/212 (47%), Gaps = 29/212 (13%)
Query: 554 LMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQER 613
LMQ ++ RQ ++ +S L+ + +K RL +G QK + + E +
Sbjct: 1006 LMQERSARQDLECDKIS------LERQNKDLKTRL-ASSEGFQKPSA----SLSQLESQN 1054
Query: 614 QHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAE 673
Q L E+ + + +L +++++ E +K + E+ R+ + +Q QLSL +
Sbjct: 1055 QLLQERLQAEE----REKTVLQSTNRKLERKVKELSIQIEDERQHVNDQK-DQLSLRVKA 1109
Query: 674 QEREQERLQKEIEEQEKMLKEKKAMTAEASELD------INNAVELEWRKIS----DSSL 723
+R+ + ++EIE + + K+ + E E++ I + + WRK S +S+L
Sbjct: 1110 LKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKASRSAAESAL 1169
Query: 724 LETMLS---QADSLHTSNSNSSGFTNSAMQYS 752
LS + DS++ +S +S T S +Q S
Sbjct: 1170 KNEGLSSDEEFDSVYDPSSIASLLTESNLQTS 1201
Score = 31.2 bits (69), Expect = 5.0
Identities = 28/135 (20%), Positives = 58/135 (42%), Gaps = 15/135 (11%)
Query: 578 DNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHLP------EKRYPKGSGFVNKN 631
D E V+++ D + L++ + E ERQ + ++ + S
Sbjct: 512 DQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHW 571
Query: 632 KMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQE---------REQERLQ 682
+ + +KE K ++L ++ +EE+ +++ +L E E R+ E L+
Sbjct: 572 QSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLK 631
Query: 683 KEIEEQEKMLKEKKA 697
KE+ ++ LKE +A
Sbjct: 632 KELLRTQEELKELQA 646
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 43.1 bits (100), Expect = 0.001
Identities = 73/364 (20%), Positives = 141/364 (38%), Gaps = 26/364 (7%)
Query: 638 SKESEELLKSKMLAFEEMRKRLEEQHAQ---QLSLLIAEQEREQERLQKEIEEQEKMLKE 694
+++++E L+ ++ R +L+EQ AQ QLS E E+ + Q+++E E+ +E
Sbjct: 811 AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 870
Query: 695 KKAMTAEASELDIN-NAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQYSF 753
K+A+ E + L + A E E R +S+ + + +A Q +
Sbjct: 871 KEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEA--------LEGSLFEVQRQLAQ 922
Query: 754 VSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRR 813
+ A G + L K ++T G Q+ + + +A +K K R
Sbjct: 923 LEARREQLEAEGQALL-LAKETLT---GELAGLRQQIIATQEKASLDKELMAQKLVQAER 978
Query: 814 LMQTDKLKQLRQTVKDTMEFIRSFQS---EAPLKRGIVSAQDASLQERVLAQLRAALYGI 870
Q +Q +D R ++ E +R + +Q QE +LA+L A +
Sbjct: 979 EAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEEL 1038
Query: 871 HDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALS---AATQKSLDRKKYMKA 927
+ + +L + E ++ L++ +K + + SL+ ++ +
Sbjct: 1039 SEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRD 1098
Query: 928 AEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVH----RLLSRQGSICRKNPKKAAKCCDN 983
A+ + V SE R L+ + + A H R L Q K + +
Sbjct: 1099 AQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEE 1158
Query: 984 LRRQ 987
LR Q
Sbjct: 1159 LRTQ 1162
Score = 33.9 bits (76), Expect = 0.78
Identities = 53/230 (23%), Positives = 93/230 (40%), Gaps = 25/230 (10%)
Query: 632 KMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKM 691
+ LG +KE E L +S EE+R +++ ++++SL +A +++EQ+ E
Sbjct: 1203 RSLGEGAKEREALRRSN----EELRSAVKKAESERISLKLANEDKEQKLALLE------- 1251
Query: 692 LKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQY 751
+ + A+ EA EL E+E ++ L+ + Q L + N+ A
Sbjct: 1252 -EARTAVGKEAGELR-TGLQEVERSRLEARRELQELRRQMKMLDSENTRLG--RELAELQ 1307
Query: 752 SFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAVAKGFLT 811
++ E T GL + + G A +V E+Q K+ F T
Sbjct: 1308 GRLALGERAEKESRRETLGLRQRLLK---GEASL---EVMRQELQVAQRKLQEQEGEFRT 1361
Query: 812 RRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGIVSAQDASLQERVLA 861
R L++ R T K ++ R + LK A+ A L R+ A
Sbjct: 1362 RERRLLGSLEEARGTEKQQLDHARGLE----LKLEAARAEAAELGLRLSA 1407
Score = 32.7 bits (73), Expect = 1.7
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 654 EMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVEL 713
E+R++L+E+ A L A QE +Q + Q Q K+L+ KK + +L + + EL
Sbjct: 143 ELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQL-LERSGEL 201
Query: 714 EWRKISDSSLLETMLSQADSLHTSNSNSS 742
E +++ D+ + + S L S+
Sbjct: 202 EQQRLRDTEHSQDLESALIRLEEEQQRSA 230
Score = 32.0 bits (71), Expect = 3.0
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 637 SSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKK 696
+ +E++ L+ + A EE +RL+ + L AE+ + Q +LQ+ EQE++L +
Sbjct: 976 AEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR---EQEELLARLE 1032
Query: 697 AMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNS 741
A E SE L+ + L E+ QA SL S +
Sbjct: 1033 AEKEELSE----EIAALQQERDEGLLLAESEKQQALSLKESEKTA 1073
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 43.1 bits (100), Expect = 0.001
Identities = 77/315 (24%), Positives = 142/315 (45%), Gaps = 45/315 (14%)
Query: 574 EQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHLPE--KRYPKGSGFVNKN 631
EQ L KV R+L+LDI LQ+ N SG+ + E++ L E KR+ +N
Sbjct: 1287 EQDLQQMQAKV-RKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKA------RN 1339
Query: 632 KMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQER-------EQERLQKE 684
+ L + K+ + K+L+ +E+ + +Q +++ L AE R Q +Q
Sbjct: 1340 QHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSL 1399
Query: 685 IEEQEKMLKEKKAM--TAEASELDINNAVE--LEWRKISD--SSLLETMLSQADSLHTSN 738
E+ K+ EK+ + +A +DI V+ + +KI + E + +Q D + ++
Sbjct: 1400 KEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETS 1459
Query: 739 SNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAK 798
+ SSG Q VS E K ++ + ++K+ SQV +L Q
Sbjct: 1460 AQSSG----DHQEQHVSVQEMQ----------ELKETLNQAETKSKSLESQVENL--QKT 1503
Query: 799 FNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGIVSAQDASLQER 858
++ A+ + + +L +LRQ ++D R+ Q E L++ I ++ + +
Sbjct: 1504 LSEKETEARNLQEQTVQLQSELSRLRQDLQD-----RTTQEE-QLRQQITEKEEKTRKAI 1557
Query: 859 VLAQLRAA-LYGIHD 872
V A+ + A L G+ D
Sbjct: 1558 VAAKSKIAHLAGVKD 1572
Score = 37.7 bits (86), Expect = 0.054
Identities = 94/499 (18%), Positives = 189/499 (37%), Gaps = 62/499 (12%)
Query: 481 EGQLTSDERGAHIMNSTCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKNCSLQT- 539
+G + S+E A M+ T AA+ K+ +P + + T L + K +
Sbjct: 366 KGAILSEEELA-AMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLD 424
Query: 540 ELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKEN 599
E+ K + K P + + R Q +S EQ + K +RL D D K++
Sbjct: 425 EIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAM-----KEIQRLQEDTDKANKQS 479
Query: 600 CPY--------VITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLA 651
+ +++Q R L E +G+ + ++ S E++ +++
Sbjct: 480 SVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVS 539
Query: 652 FEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAV 711
+ + +EE Q LL+A +E + R ++E E + E + A +
Sbjct: 540 Y----RNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESA----LTELE 591
Query: 712 ELEWRKISDSSLLETMLSQADSLHTSNSNSSG-----FTNSAMQYSFVSANEAPFYLWGS 766
+L + L+++++ Q D S ++G +S S S + P
Sbjct: 592 QLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTV 651
Query: 767 STSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQT 826
ST + + AK Q+ EI + K A +Q ++L++L++
Sbjct: 652 STPAPVPVIESTEAIEAKAALKQL--QEIFENYKKEKA------ENEKIQNEQLEKLQEQ 703
Query: 827 VKDTMEFIRSFQSEAPLKRGIVSAQDASLQERVLA-------------QLRAALYGIHDI 873
V D +RS ++ + S + LQ+ V +L A I
Sbjct: 704 VTD----LRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQI 759
Query: 874 FFVM-----DAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAA 928
M A E++++ EVR E + ++ + +K V LS + L ++
Sbjct: 760 INTMTQDLRGANEKLAV----AEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLL 815
Query: 929 EMGMPNKKFLVKQNPSETR 947
+ + +++++ +ET+
Sbjct: 816 LTNLQTIQGILERSETETK 834
Score = 33.1 bits (74), Expect = 1.3
Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 17/180 (9%)
Query: 532 EKNCSLQTELNKSYDVKNPSP--LLMQNQNTRQQMD--TPMVSCGNEQFLDNSFEKVKRR 587
++N ++Q++ ++ + L+ N+ Q+++ T V NE+ +++ K
Sbjct: 104 DRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN--TTKGE 161
Query: 588 LDLDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNK-NKMLGTSSKESEELLK 646
L L +D LQ + EQE++ L + + K +++L ++ E+L+
Sbjct: 162 LQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILE 221
Query: 647 SK--MLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASE 704
K + +E RLEEQ + + E LQK +E+ LKE K A E
Sbjct: 222 LKCNLENKKEEVSRLEEQ--------MNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 273
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 42.7 bits (99), Expect = 0.002
Identities = 42/164 (25%), Positives = 76/164 (46%), Gaps = 14/164 (8%)
Query: 608 ITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKES-----EELLKSKMLAFEEMRKRLEE- 661
+ +QER+ L +K S + + K L +S + EE++K K L EE+++ L+E
Sbjct: 241 LEQQEREKLQQKELQIDS-LLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDEL 299
Query: 662 ----QHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRK 717
Q +Q L+ + E E + +E++ E+ LK K+A ++S + L+ +
Sbjct: 300 DKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKY 359
Query: 718 ISDSSLLETMLSQADS---LHTSNSNSSGFTNSAMQYSFVSANE 758
S LE + +Q +S L S NS++Q A +
Sbjct: 360 DSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGK 403
Score = 38.5 bits (88), Expect = 0.032
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
Query: 628 VNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEE 687
VN+N+ + + LK K + ++ R++L+++ Q SLL E+E QK
Sbjct: 218 VNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSF 277
Query: 688 QEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADS 733
QE+M+KEK E + ++ +L+ ++ L++ + +A S
Sbjct: 278 QEEMVKEKNLFEEELKQ-TLDELDKLQQKEEQAERLVKQLEEEAKS 322
Score = 34.7 bits (78), Expect = 0.46
Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 34/191 (17%)
Query: 532 EKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLD 591
EK + EL KS + LL+Q + V+ FE K +
Sbjct: 332 EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTA--------QFESYKALTASE 383
Query: 592 IDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVN-KNKMLGTSSKESEEL-----L 645
I+ L+ EN L EK G + ++++L T S E + L
Sbjct: 384 IEDLKLEN--------------SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDL 429
Query: 646 KSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASEL 705
++K E K + Q+++ L + ++++E +K++E++E EK+ TAE +E
Sbjct: 430 QTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTE- 488
Query: 706 DINNAVELEWR 716
+IN +WR
Sbjct: 489 EIN-----KWR 494
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 42.7 bits (99), Expect = 0.002
Identities = 42/164 (25%), Positives = 76/164 (46%), Gaps = 14/164 (8%)
Query: 608 ITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKES-----EELLKSKMLAFEEMRKRLEE- 661
+ +QER+ L +K S + + K L +S + EE++K K L EE+++ L+E
Sbjct: 328 LEQQEREKLQQKELQIDS-LLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDEL 386
Query: 662 ----QHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRK 717
Q +Q L+ + E E + +E++ E+ LK K+A ++S + L+ +
Sbjct: 387 DKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKY 446
Query: 718 ISDSSLLETMLSQADS---LHTSNSNSSGFTNSAMQYSFVSANE 758
S LE + +Q +S L S NS++Q A +
Sbjct: 447 DSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGK 490
Score = 38.5 bits (88), Expect = 0.032
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
Query: 628 VNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEE 687
VN+N+ + + LK K + ++ R++L+++ Q SLL E+E QK
Sbjct: 305 VNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSF 364
Query: 688 QEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADS 733
QE+M+KEK E + ++ +L+ ++ L++ + +A S
Sbjct: 365 QEEMVKEKNLFEEELKQ-TLDELDKLQQKEEQAERLVKQLEEEAKS 409
Score = 34.7 bits (78), Expect = 0.46
Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 34/191 (17%)
Query: 532 EKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLD 591
EK + EL KS + LL+Q + V+ FE K +
Sbjct: 419 EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTA--------QFESYKALTASE 470
Query: 592 IDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVN-KNKMLGTSSKESEEL-----L 645
I+ L+ EN L EK G + ++++L T S E + L
Sbjct: 471 IEDLKLEN--------------SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDL 516
Query: 646 KSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASEL 705
++K E K + Q+++ L + ++++E +K++E++E EK+ TAE +E
Sbjct: 517 QTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTE- 575
Query: 706 DINNAVELEWR 716
+IN +WR
Sbjct: 576 EIN-----KWR 581
Score = 30.4 bits (67), Expect = 8.6
Identities = 24/108 (22%), Positives = 50/108 (46%), Gaps = 3/108 (2%)
Query: 603 VITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQ 662
V+ ++ Q+ Q +++ K + V+K+ L S+++ + K + ++ E+
Sbjct: 31 VLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKKESQKNDKDLKILEK 90
Query: 663 HAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNA 710
++ +L+ E+ + R+Q E EKM A E + L NNA
Sbjct: 91 ---EIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNA 135
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 42.7 bits (99), Expect = 0.002
Identities = 42/164 (25%), Positives = 76/164 (46%), Gaps = 14/164 (8%)
Query: 608 ITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKES-----EELLKSKMLAFEEMRKRLEE- 661
+ +QER+ L +K S + + K L +S + EE++K K L EE+++ L+E
Sbjct: 312 LEQQEREKLQQKELQIDS-LLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDEL 370
Query: 662 ----QHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRK 717
Q +Q L+ + E E + +E++ E+ LK K+A ++S + L+ +
Sbjct: 371 DKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKY 430
Query: 718 ISDSSLLETMLSQADS---LHTSNSNSSGFTNSAMQYSFVSANE 758
S LE + +Q +S L S NS++Q A +
Sbjct: 431 DSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGK 474
Score = 38.5 bits (88), Expect = 0.032
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
Query: 628 VNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEE 687
VN+N+ + + LK K + ++ R++L+++ Q SLL E+E QK
Sbjct: 289 VNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSF 348
Query: 688 QEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADS 733
QE+M+KEK E + ++ +L+ ++ L++ + +A S
Sbjct: 349 QEEMVKEKNLFEEELKQ-TLDELDKLQQKEEQAERLVKQLEEEAKS 393
Score = 34.7 bits (78), Expect = 0.46
Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 34/191 (17%)
Query: 532 EKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLD 591
EK + EL KS + LL+Q + V+ FE K +
Sbjct: 403 EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTA--------QFESYKALTASE 454
Query: 592 IDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVN-KNKMLGTSSKESEEL-----L 645
I+ L+ EN L EK G + ++++L T S E + L
Sbjct: 455 IEDLKLEN--------------SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDL 500
Query: 646 KSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASEL 705
++K E K + Q+++ L + ++++E +K++E++E EK+ TAE +E
Sbjct: 501 QTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTE- 559
Query: 706 DINNAVELEWR 716
+IN +WR
Sbjct: 560 EIN-----KWR 565
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 42.7 bits (99), Expect = 0.002
Identities = 42/164 (25%), Positives = 76/164 (46%), Gaps = 14/164 (8%)
Query: 608 ITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKES-----EELLKSKMLAFEEMRKRLEE- 661
+ +QER+ L +K S + + K L +S + EE++K K L EE+++ L+E
Sbjct: 327 LEQQEREKLQQKELQIDS-LLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDEL 385
Query: 662 ----QHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRK 717
Q +Q L+ + E E + +E++ E+ LK K+A ++S + L+ +
Sbjct: 386 DKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKY 445
Query: 718 ISDSSLLETMLSQADS---LHTSNSNSSGFTNSAMQYSFVSANE 758
S LE + +Q +S L S NS++Q A +
Sbjct: 446 DSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGK 489
Score = 38.5 bits (88), Expect = 0.032
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
Query: 628 VNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEE 687
VN+N+ + + LK K + ++ R++L+++ Q SLL E+E QK
Sbjct: 304 VNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSF 363
Query: 688 QEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADS 733
QE+M+KEK E + ++ +L+ ++ L++ + +A S
Sbjct: 364 QEEMVKEKNLFEEELKQ-TLDELDKLQQKEEQAERLVKQLEEEAKS 408
Score = 34.7 bits (78), Expect = 0.46
Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 34/191 (17%)
Query: 532 EKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLD 591
EK + EL KS + LL+Q + V+ FE K +
Sbjct: 418 EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTA--------QFESYKALTASE 469
Query: 592 IDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVN-KNKMLGTSSKESEEL-----L 645
I+ L+ EN L EK G + ++++L T S E + L
Sbjct: 470 IEDLKLEN--------------SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDL 515
Query: 646 KSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASEL 705
++K E K + Q+++ L + ++++E +K++E++E EK+ TAE +E
Sbjct: 516 QTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTE- 574
Query: 706 DINNAVELEWR 716
+IN +WR
Sbjct: 575 EIN-----KWR 580
Score = 32.0 bits (71), Expect = 3.0
Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 603 VITSGITEQERQHLPEKRYPKGSGFVNKN--------KMLGTSSKESEELLKSKMLAFEE 654
V+ ++ Q+ Q +++ K + V+K+ K+ + SKES++ K + +E
Sbjct: 31 VLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKESQKNDKDLKILEKE 90
Query: 655 MRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELE 714
+R L+E+ AQ + E E E+ + +EK T E +++ EL
Sbjct: 91 IRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELL 150
Query: 715 WRKISDS 721
K S++
Sbjct: 151 KSKFSEN 157
>gi|38327558 guanylate binding protein 2, interferon-inducible [Homo
sapiens]
Length = 591
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/63 (36%), Positives = 42/63 (66%), Gaps = 3/63 (4%)
Query: 632 KMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKM 691
KML K++EE+++ K +++E K+L E+ + + L+AEQE+ L +++EQE++
Sbjct: 502 KMLEEIQKKNEEMMEQKEKSYQEHVKQLTEKMERDRAQLMAEQEK---TLALKLQEQERL 558
Query: 692 LKE 694
LKE
Sbjct: 559 LKE 561
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 41.6 bits (96), Expect = 0.004
Identities = 54/254 (21%), Positives = 109/254 (42%), Gaps = 33/254 (12%)
Query: 639 KESEELLKSKMLAFEEMRKRLEEQHAQ-------------QLSLLIAEQEREQERLQKEI 685
+ESE + + A + M +E+ H Q QLS L E+ Q RL+++
Sbjct: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1752
Query: 686 EEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFT 745
E+ +++K+ KA A+AS D+ +L+ ++ +++ + L + L S
Sbjct: 1753 EDMNELMKKHKAAVAQASR-DLAQINDLQ-AQLEEANKEKQELQ--EKLQALQSQVEFLE 1808
Query: 746 NSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAV 805
S + S VS EA + +L F R + + + + ++ K+T
Sbjct: 1809 QSMVDKSLVSRQEAK----------IRELETRLEFERTQVKRLESLASRLKENMEKLTEE 1858
Query: 806 AKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSF---QSEAPLKRGIVSAQDASLQ---ERV 859
+ + ++ K+L++ ++DT E + ++EA K+ + SL+ + +
Sbjct: 1859 RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
Query: 860 LAQLRAALYGIHDI 873
A L+ A I D+
Sbjct: 1919 QADLKLAFKRIGDL 1932
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 41.6 bits (96), Expect = 0.004
Identities = 54/254 (21%), Positives = 109/254 (42%), Gaps = 33/254 (12%)
Query: 639 KESEELLKSKMLAFEEMRKRLEEQHAQ-------------QLSLLIAEQEREQERLQKEI 685
+ESE + + A + M +E+ H Q QLS L E+ Q RL+++
Sbjct: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1752
Query: 686 EEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFT 745
E+ +++K+ KA A+AS D+ +L+ ++ +++ + L + L S
Sbjct: 1753 EDMNELMKKHKAAVAQASR-DLAQINDLQ-AQLEEANKEKQELQ--EKLQALQSQVEFLE 1808
Query: 746 NSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAV 805
S + S VS EA + +L F R + + + + ++ K+T
Sbjct: 1809 QSMVDKSLVSRQEAK----------IRELETRLEFERTQVKRLESLASRLKENMEKLTEE 1858
Query: 806 AKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSF---QSEAPLKRGIVSAQDASLQ---ERV 859
+ + ++ K+L++ ++DT E + ++EA K+ + SL+ + +
Sbjct: 1859 RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
Query: 860 LAQLRAALYGIHDI 873
A L+ A I D+
Sbjct: 1919 QADLKLAFKRIGDL 1932
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 41.6 bits (96), Expect = 0.004
Identities = 47/182 (25%), Positives = 86/182 (47%), Gaps = 11/182 (6%)
Query: 530 MLEKNCSLQTELNKSYDVKNPSPLLMQ-NQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRL 588
ML S + KS+ +K +PL M + RQ+++ EQ E+ KRR
Sbjct: 504 MLMTPTSAPRSVMKSF-IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRR 562
Query: 589 DLDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSK 648
++ ++E V+ + ++ + +K+ + +++ + +EE K K
Sbjct: 563 LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 622
Query: 649 MLA--FEEMR-KRLEEQHAQQLSLLIAEQE--REQERLQKEIEEQEKMLKEKKAMTAEAS 703
A EE+ +R +E+ A++L L E+E R QE LQK+ EE+++ L++ AEA
Sbjct: 623 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK----AAEAK 678
Query: 704 EL 705
L
Sbjct: 679 RL 680
Score = 39.3 bits (90), Expect = 0.018
Identities = 28/105 (26%), Positives = 48/105 (45%)
Query: 628 VNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEE 687
V +N+ML T + ++KS + +R +E+ Q+L L ++E EQ R QK E+
Sbjct: 499 VQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEED 558
Query: 688 QEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQAD 732
+ + L+E K E + +E K +E +Q D
Sbjct: 559 KRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
Score = 37.4 bits (85), Expect = 0.070
Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 610 EQERQH--LPEKRYPKGSGFVNKN---KMLGTSSKESEELLKSKMLAFEEMRKRLEEQHA 664
E+ER+H L +K+ + + K K L ++ + + E +R +E+
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710
Query: 665 QQLSLLIAEQEREQERLQ--KEIEEQEKMLK-EKKAMTAEASE 704
Q+ L E+ REQERLQ +E++E+EK L+ +K+ + E E
Sbjct: 711 QERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEE 753
Score = 30.4 bits (67), Expect = 8.6
Identities = 26/106 (24%), Positives = 55/106 (51%), Gaps = 23/106 (21%)
Query: 610 EQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSL 669
EQERQ ++R + + + +E +E K+ L E++++ LEE+
Sbjct: 710 EQERQLAEQER--------RREQERLQAERELQEREKALRLQKEQLQRELEEK------- 754
Query: 670 LIAEQEREQERL-QKEIEEQEKMLKEKKAMTAEASELDINNAVELE 714
+++ EQ+RL +++++E++ EKKA A + +N V+++
Sbjct: 755 ---KKKEEQQRLAERQLQEEQ----EKKAKEAAGASKALNVTVDVQ 793
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 41.2 bits (95), Expect = 0.005
Identities = 147/737 (19%), Positives = 277/737 (37%), Gaps = 139/737 (18%)
Query: 2 EEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEKQ 61
EE + + K A + A +S A+ + + S L + K+ +++
Sbjct: 498 EEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLH-------SKLTDTLVSKQQLEQRL 550
Query: 62 KALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVPA 121
L +K+VN++++L +VQ+IL+ + KA Q +T S V A
Sbjct: 551 MQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIA 610
Query: 122 TFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLARDSEGFNSPKQCDSSNISH 181
TE S A++ D++ E++ K D + N + + +
Sbjct: 611 EKDKQI-KQTEDSLASERDRLTS-----KEEELK--------DIQNMNFLLKAEVQKLQA 656
Query: 182 VENE--AFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSLQNLMKKSKEYI 239
+ NE A Q + D + E+Q + N M++ K
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQ------------LQHEISNKMEEFKILN 704
Query: 240 EREQSRRSLRGSMNRIVNESHLDKEHDAVEVAD-CVKEKGQLTGKHCVSVIPDKPSLNKS 298
++ ++ +S + +V+E D VE + C++EK + L
Sbjct: 705 DQNKALKSEVQKLQTLVSEQ---PNKDVVEQMEKCIQEKDE--------------KLKTV 747
Query: 299 NVLLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLT 358
LL+ Q ++ + A IRT + ++ + D K +N+ +
Sbjct: 748 EELLETGLIQVATKEEELNA--------IRTENSSLTKEVQDLKA-----KQNDQV---- 790
Query: 359 GSYAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDEN 418
S+A L + +H + + S +L A L KE+ + + Q+
Sbjct: 791 -SFASLVE---ELKKVIHEKDGKIKSVEELL-----EAELLKVANKEKTVQDLKQE---- 837
Query: 419 TNVPEIMPKLPTDLAGVCSSKVYVGKNTSEVKE--DVVLGKSNQVCQSSGNHLENK---- 472
+ L ++ V K TS+V+E +++ GK Q+ + LE K
Sbjct: 838 ------IKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQM-NTMKAVLEEKEKDL 890
Query: 473 VTHGLVTVEGQLTSDERGAHIMNSTCAAMPKLHEPYASSQ-----CIASPNFGTVSGLKP 527
G + Q ++ AH+ A L E ++SQ + + L+
Sbjct: 891 ANTGKWLQDLQEENESLKAHVQE---VAQHNLKEASSASQFEELEIVLKEKENELKRLE- 946
Query: 528 ASMLEKNCSLQTELNKSYDVKNPSPLL------MQNQNTRQQMDTPMVSCGNEQFLDNSF 581
A + E+ L ++ DV++ + L ++ QN +Q P +E+ L
Sbjct: 947 AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP----HEELLKVIS 1002
Query: 582 EKVKRRLDL--DIDGLQ-------KENCPYVITSGITEQERQHLPEKRYPKGS------- 625
E+ K L ++D L+ K+N E E + + +K +PK S
Sbjct: 1003 EREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSY 1062
Query: 626 -----GFVNKNK--MLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQ 678
GF K K M GTS E ++L+ K+ +EM L+ + ++ ++AE E
Sbjct: 1063 GEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLE-CEKYKSVLAETEGIL 1121
Query: 679 ERLQKEIEEQEKMLKEK 695
++LQ+ +E++E K K
Sbjct: 1122 QKLQRSVEQEENKWKVK 1138
Score = 35.4 bits (80), Expect = 0.27
Identities = 31/147 (21%), Positives = 68/147 (46%), Gaps = 10/147 (6%)
Query: 590 LDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKM 649
L + +QK+N T + + E+R+ + ++ K + +++ L+SK
Sbjct: 469 LQQEEVQKKNAEQAATQLKVQLQEA---ERRWEEVQSYIRKRT---AEHEAAQQDLQSKF 522
Query: 650 LAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINN 709
+A E ++ H++ L+++Q+ EQ +Q EQ+++ KE+ L+ N
Sbjct: 523 VAKEN---EVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNE 579
Query: 710 AVELEWRKISDSSLLETMLS-QADSLH 735
A++ + ++ +T S A+ LH
Sbjct: 580 ALKAQIQQFHSQIAAQTSASVLAEELH 606
Score = 31.2 bits (69), Expect = 5.0
Identities = 32/160 (20%), Positives = 72/160 (45%), Gaps = 15/160 (9%)
Query: 558 QNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENCPYV-ITSGITEQERQHL 616
++ + ++ ++ N++ ++ + L +I +Q E + ITS + QE Q+L
Sbjct: 811 KSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV--QELQNL 868
Query: 617 ----PEKRYPKGSGFVNKNKMLGTSSK------ESEELLKSKM--LAFEEMRKRLEEQHA 664
E+ + K K L + K E E LK+ + +A +++
Sbjct: 869 LKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQF 928
Query: 665 QQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASE 704
++L +++ E+E E +RL+ ++E+E L K + + +
Sbjct: 929 EELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 41.2 bits (95), Expect = 0.005
Identities = 54/251 (21%), Positives = 103/251 (41%), Gaps = 25/251 (9%)
Query: 503 KLHEPYASSQCIASPNFGTVSGLKPASMLEKNC-SLQTELNK---SYDVKNPSPLLMQNQ 558
K + QC+A+ TV K E C +LQ E+ K S + L Q
Sbjct: 281 KKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQ 340
Query: 559 NTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLD------IDGLQKENCPYVITSGITEQE 612
+ + + + C L+++ K+++ L LD I LQ+E S + E+E
Sbjct: 341 AAQCKEEAALAGC----HLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKE 396
Query: 613 RQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKS---KMLAFEEMRKRLEEQHAQQLSL 669
+ ++ + L S KE +L K+ + + +M R++ QH +Q S+
Sbjct: 397 QTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSI 456
Query: 670 LIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLS 729
+L+++++E K+L++K+ ++ E + ELE + +T+
Sbjct: 457 KC--------KLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKE 508
Query: 730 QADSLHTSNSN 740
+ L N N
Sbjct: 509 NSRKLEEENEN 519
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 41.2 bits (95), Expect = 0.005
Identities = 54/251 (21%), Positives = 103/251 (41%), Gaps = 25/251 (9%)
Query: 503 KLHEPYASSQCIASPNFGTVSGLKPASMLEKNC-SLQTELNK---SYDVKNPSPLLMQNQ 558
K + QC+A+ TV K E C +LQ E+ K S + L Q
Sbjct: 426 KKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQ 485
Query: 559 NTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLD------IDGLQKENCPYVITSGITEQE 612
+ + + + C L+++ K+++ L LD I LQ+E S + E+E
Sbjct: 486 AAQCKEEAALAGC----HLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKE 541
Query: 613 RQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKS---KMLAFEEMRKRLEEQHAQQLSL 669
+ ++ + L S KE +L K+ + + +M R++ QH +Q S+
Sbjct: 542 QTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSI 601
Query: 670 LIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLS 729
+L+++++E K+L++K+ ++ E + ELE + +T+
Sbjct: 602 KC--------KLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKE 653
Query: 730 QADSLHTSNSN 740
+ L N N
Sbjct: 654 NSRKLEEENEN 664
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 41.2 bits (95), Expect = 0.005
Identities = 60/342 (17%), Positives = 134/342 (39%), Gaps = 44/342 (12%)
Query: 614 QHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAE 673
Q LPE+ + + K+ T + E + L E+ R+ L EQ ++ L
Sbjct: 327 QRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQL 386
Query: 674 QEREQERLQKEIEEQEKML---------------------KEKKAMTAEASELDINNAVE 712
+ EQER ++E +EQE+ + K+ EA++ ++ +
Sbjct: 387 ERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQ 446
Query: 713 LEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLT 772
LEW + LL + + + + +++ + N+ L G
Sbjct: 447 LEWERNRRQELLNQRNKEQEDIVVLKAK-----KKTLEFELEALNDKKHQLEGKLQDIRC 501
Query: 773 KLSVTRPFGRAKTRWSQVFSLEI---QAKFNKITAVAKGFLTRRLMQTDKLKQLRQTV-- 827
+L+ R + + ++ EI Q + + + + + + D+LKQ++Q
Sbjct: 502 RLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLH 561
Query: 828 KDTMEFIRSFQSEAPLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILH 887
+D++ ++ L R + Q +++ ++L+ DIF + L
Sbjct: 562 RDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEI-----DIF--------NNQLK 608
Query: 888 HDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAE 929
RE+ ++ L++ M++ R+ +K ++ +K + A+
Sbjct: 609 ELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQ 650
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 41.2 bits (95), Expect = 0.005
Identities = 60/342 (17%), Positives = 134/342 (39%), Gaps = 44/342 (12%)
Query: 614 QHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAE 673
Q LPE+ + + K+ T + E + L E+ R+ L EQ ++ L
Sbjct: 327 QRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQL 386
Query: 674 QEREQERLQKEIEEQEKML---------------------KEKKAMTAEASELDINNAVE 712
+ EQER ++E +EQE+ + K+ EA++ ++ +
Sbjct: 387 ERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQ 446
Query: 713 LEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLT 772
LEW + LL + + + + +++ + N+ L G
Sbjct: 447 LEWERNRRQELLNQRNKEQEDIVVLKAK-----KKTLEFELEALNDKKHQLEGKLQDIRC 501
Query: 773 KLSVTRPFGRAKTRWSQVFSLEI---QAKFNKITAVAKGFLTRRLMQTDKLKQLRQTV-- 827
+L+ R + + ++ EI Q + + + + + + D+LKQ++Q
Sbjct: 502 RLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLH 561
Query: 828 KDTMEFIRSFQSEAPLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILH 887
+D++ ++ L R + Q +++ ++L+ DIF + L
Sbjct: 562 RDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEI-----DIF--------NNQLK 608
Query: 888 HDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAE 929
RE+ ++ L++ M++ R+ +K ++ +K + A+
Sbjct: 609 ELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQ 650
>gi|45237195 Janus kinase and microtubule interacting protein 2
[Homo sapiens]
Length = 810
Score = 41.2 bits (95), Expect = 0.005
Identities = 67/292 (22%), Positives = 125/292 (42%), Gaps = 33/292 (11%)
Query: 630 KNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEI--EE 687
K+ +L T K +L + KM + +R+ L +QH Q++S + ++ E +RL+ +
Sbjct: 65 KHTVLVTELKA--KLHEEKMKELQAVRENLIKQHEQEMSRTVKVRDGEIQRLKSALCALR 122
Query: 688 QEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNS 747
K + A+T EA E E RK+ D+ L+ + AD L T+ ++
Sbjct: 123 DGSSDKVRTALTIEARE---------EARKLFDTERLKLLQEIAD-LKTAKKQVDEALSN 172
Query: 748 AMQYSFVSANEAPFYLWGSSTSGLTKL------SVTRPFGRAKTRWSQVFSLEIQAKFNK 801
+Q + A + S ++K+ + R K + +FSLE K
Sbjct: 173 MIQADKIKAGDLRSE-HQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLE------K 225
Query: 802 ITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRG----IVSAQDASLQE 857
G++ + +Q + L + VK+ + S + E P + G S+ D +
Sbjct: 226 ELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQ 285
Query: 858 RVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKE-KMLRQMDKMKSPR 908
+ +A+L A + + D ++ ER +L RE K+ K L + +K + R
Sbjct: 286 KRIAELNATIRKLEDRNTLL-GDERNELLKRVRETEKQCKPLLERNKCLAKR 336
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 41.2 bits (95), Expect = 0.005
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 610 EQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSL 669
E+E + +K+ P + + L +E E + + EE KRLEE A++
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE----EERIKRLEELEAKRKEE 379
Query: 670 LIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASE 704
EQE+ + + QKE E +E++ KE K +T E
Sbjct: 380 ERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 40.8 bits (94), Expect = 0.006
Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 6/100 (6%)
Query: 610 EQERQHLPEKRYPKGSGFVNKNKMLGTSSK--ESEELL---KSKMLAFEEMRKRLEEQHA 664
E+E+ H EK + + ++KM K E EE + + K+ EE R+ EE+
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 665 QQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASE 704
+Q + ++E+ QE+ +K I EQE+ ++E++ MT E E
Sbjct: 609 KQEEKIREQEEKIQEQEEK-IREQEEKIREQEEMTQEQEE 647
Score = 37.4 bits (85), Expect = 0.070
Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
Query: 610 EQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSL 669
E++RQ EK + + + + + ++ E + K+ EEM + EE+ +Q
Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ-EEKIREQEEMTQEQEEKMGEQEEK 655
Query: 670 LIAEQEREQE------RLQKEIEEQEKMLKEKKAMTAEASEL 705
+ ++E+ QE R +++I EQEK ++E++ E E+
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697
Score = 34.7 bits (78), Expect = 0.46
Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 13/99 (13%)
Query: 608 ITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRK-RLEEQHAQQ 666
I EQE+ EKR + + + K+ E EE+ + K E+ K R +E+ +
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKI-----HEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
Query: 667 LSLLIAEQE---REQE----RLQKEIEEQEKMLKEKKAM 698
I EQE REQE R +++I EQE+M +E++ M
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM 553
Score = 33.1 bits (74), Expect = 1.3
Identities = 17/63 (26%), Positives = 36/63 (57%)
Query: 639 KESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAM 698
+E E++ + + +E + +E+ ++ I EQE++ R +++I EQEK+ +E+K
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 473
Query: 699 TAE 701
E
Sbjct: 474 EQE 476
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/152 (21%), Positives = 67/152 (44%), Gaps = 18/152 (11%)
Query: 582 EKVKRRLDLDIDGLQK--ENCPYVITSGITEQERQHLPEKRYP---KGSGFVNKNKMLGT 636
E K + L++ L++ E ++ + E HL ++ K V +N++
Sbjct: 234 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
Query: 637 SSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKK 696
+++ EE + + +E ++++EQ E+ REQE ++I EQE+ ++ ++
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQE---------EKIREQE---EKIREQEEKMRRQE 341
Query: 697 AMTAEASELDINNAVELEWRKISDSSLLETML 728
M E E + E+ W K E M+
Sbjct: 342 EMMWEKEE-KMRRQEEMMWEKEEKMRRQEEMM 372
Score = 32.3 bits (72), Expect = 2.3
Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 11/103 (10%)
Query: 640 ESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQE------RLQKEIEEQEKMLK 693
E EE ++ E K E++ +Q I EQE+ QE R +++I EQE+ ++
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 694 E-KKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLH 735
E +K M + ++ + E ++ E M Q + +H
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQ----EEMWRQEEKIH 486
Score = 31.2 bits (69), Expect = 5.0
Identities = 23/102 (22%), Positives = 48/102 (47%), Gaps = 7/102 (6%)
Query: 639 KESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAM 698
++ E++ + + + EE R+ EE Q+ I EQE + +K E++EK+ K+++ +
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEK--IHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 699 TAEASEL-----DINNAVELEWRKISDSSLLETMLSQADSLH 735
+ ++ I E WR+ E M + + +H
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Score = 30.8 bits (68), Expect = 6.6
Identities = 16/70 (22%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 639 KESEELLKSKMLAFEEMRKRLEEQHA---QQLSLLIAEQEREQERLQKEIEEQEKMLKEK 695
+E EE + + E K++ EQ +Q ++ ++E+ E+ +K E++EKM +++
Sbjct: 664 QEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
Query: 696 KAMTAEASEL 705
+ M + ++
Sbjct: 724 EKMRRQEEKM 733
Score = 30.4 bits (67), Expect = 8.6
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
Query: 638 SKESEELL---KSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKE 694
++E EE + + KM EE + EE +Q I EQE++ +++I EQE+M++E
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK-IREQEKKIREQEEKIREQEEMMQE 700
Query: 695 KKAMTAEASE 704
++ E E
Sbjct: 701 QEEKMWEQEE 710
Score = 30.4 bits (67), Expect = 8.6
Identities = 16/67 (23%), Positives = 38/67 (56%), Gaps = 4/67 (5%)
Query: 639 KESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAM 698
+E EE ++ + EEM + EE+ +Q + ++E+ QE+ +K ++EKM +++ +
Sbjct: 685 REQEEKIREQ----EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 740
Query: 699 TAEASEL 705
+ ++
Sbjct: 741 RQQEEKM 747
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 40.8 bits (94), Expect = 0.006
Identities = 74/356 (20%), Positives = 142/356 (39%), Gaps = 52/356 (14%)
Query: 625 SGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQ---------- 674
+G ++ ++ KES++LL+ + L E K E++ + L+ E
Sbjct: 61 TGTFSREALMAYWEKESQKLLEKERLG--ECGKVAEDKEESEEELIFTESNSEVSEEVYT 118
Query: 675 EREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSL 734
E E+E Q+E EE++ +E+ TA+ IN V + SD+S + SQ +++
Sbjct: 119 EEEEEESQEEEEEEDSDEEERTIETAKG----INGTVNYD-SVNSDNSKPKIFKSQIENI 173
Query: 735 HTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSST---SGLTKLSVTRPFGRAKTRWSQVF 791
+ +N ++ T S A + G+ T L K+ P + + +
Sbjct: 174 NLTNGSNGRNTES----------PAAIHPCGNPTVIEDALDKIKSNDP-DTTEVNLNNIE 222
Query: 792 SLEIQ-----AKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPL--K 844
++ Q A+ K V K F D + E I + E+
Sbjct: 223 NITTQTLTRFAEALKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITG 282
Query: 845 RGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKM 904
+GI++ A VL +LR H+ +M + M I+ +E L ++
Sbjct: 283 KGILAIMRALQHNTVLTELR-----FHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFEL 337
Query: 905 KSPRVALSAATQKSLDRKKYMKAAEM-------GMPNKKFLVKQ--NPSETRVLQP 951
PR+++++ +++D+++ + E G PN + V Q PS + + P
Sbjct: 338 PGPRMSMTSILTRNMDKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSP 393
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 40.4 bits (93), Expect = 0.008
Identities = 47/227 (20%), Positives = 93/227 (40%), Gaps = 39/227 (17%)
Query: 532 EKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLD 591
E+ +Q ++N+ ++KN L + T + M+T + Q L+ ++E+VK
Sbjct: 1148 EEMSEMQKKINEIENLKNE---LKNKELTLEHMETERLELA--QKLNENYEEVK------ 1196
Query: 592 IDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEEL----LKS 647
+ KE E ER HL G++ + + G +KE ++ LK
Sbjct: 1197 --SITKERKVLKELQKSFETERDHL--------RGYIREIEATGLQTKEELKIAHIHLKE 1246
Query: 648 KMLAFEEMRKRLEEQHAQQLSLLIAEQER------------EQERLQ--KEIEEQEKMLK 693
+E+R+ + E+ AQ ++ E+ EQE L KE+ E ++ +
Sbjct: 1247 HQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMN 1306
Query: 694 EKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSN 740
E + +T +++ D +E ++ + + + SL N
Sbjct: 1307 ELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDN 1353
Score = 33.5 bits (75), Expect = 1.0
Identities = 73/377 (19%), Positives = 144/377 (38%), Gaps = 45/377 (11%)
Query: 628 VNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEE 687
VN+ K K + L+S E+ RL+E +++ ++I E+E E +R+Q+ ++
Sbjct: 1547 VNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQ-EEIQIMIKEKE-EMKRVQEALQI 1604
Query: 688 QEKMLKEK-KAMTAEASELDINNAVELEWRKISDS-----------SLLETMLSQADSLH 735
+ LKE K + A+ E L+ ++++ ET +++
Sbjct: 1605 ERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIE 1664
Query: 736 TSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEI 795
T N + + ++ E S L V R + R + LE
Sbjct: 1665 TENIRLTQILHENLEEMRSVTKER-----DDLRSVEETLKVERDQLKENLRETITRDLEK 1719
Query: 796 QAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGIVSAQDASL 855
Q + + K + + +LR V + I + Q + + AQD +
Sbjct: 1720 QEELKIVHMHLK-------EHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKI 1772
Query: 856 QERV------LAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRV 909
QE + L + + + + I V + +++S + D E K+ ++ ++K+
Sbjct: 1773 QEELRIAHMHLKEQQETIDKLRGI--VSEKTDKLSNMQKDLENSNAKLQEKIQELKANEH 1830
Query: 910 ALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGSI 969
L T K + K +EM KK + Q+ + +++ N +H L S+
Sbjct: 1831 QL--ITLKKDVNETQKKVSEMEQ-LKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSV 1887
Query: 970 CRKNPKKAAKCCDNLRR 986
++ DNLRR
Sbjct: 1888 MKER--------DNLRR 1896
Score = 32.0 bits (71), Expect = 3.0
Identities = 136/753 (18%), Positives = 283/753 (37%), Gaps = 102/753 (13%)
Query: 51 EKRKEMQQEKQKALDV-----EARKQVNRKKALLTRVQE---ILDNVQVRKAPNASDFDQ 102
EK +++Q+++Q+ L+V E +K++N + L ++ L++++ + A ++
Sbjct: 1131 EKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNE 1190
Query: 103 WEMETVYSNSEVRNLNVPATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLA 162
E V S ++ R V SF + +H + A L +++ K I L
Sbjct: 1191 -NYEEVKSITKERK--VLKELQKSFETERDHLRGYIREIEA--TGLQTKEELKIAHIHLK 1245
Query: 163 RDSEGFNSPKQCDSSNISHVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPD 222
E + ++ S + + N + S QE + P EQ+ LP + EV
Sbjct: 1246 EHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEI----PVLHEEQELLPNVKEVSET 1301
Query: 223 PYVMSLQNLMKKSKEYIEREQSRRSLRGSMNRI-VNESHLDKEHDAVEVADCVKEKGQL- 280
M+ L+ E + S R M R+ +NE + + E+ KE+ L
Sbjct: 1302 QETMNELELLT---EQSTTKDSTTLARIEMERLRLNEKFQESQE---EIKSLTKERDNLK 1355
Query: 281 TGKHCVSVIPD--KPSLNKSNVLLQGA-STQASSMSM------------------PVLAS 319
T K + V D K + ++ +Q + S Q S++M P ++
Sbjct: 1356 TIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSA 1415
Query: 320 FSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLTGSYAKLPSPEPSMSPKMHRRR 379
+++I + + ES+ + K + + ++ + S + H
Sbjct: 1416 LLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLET 1475
Query: 380 SRTSSACHILINNP---INACELSPKGKEQAMDLIIQDTDENTNVPEIMPKLPTDLAGVC 436
H + IN ++ KE + I + + I KL + +
Sbjct: 1476 EEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEA------INDKLQNKIQEIY 1529
Query: 437 SSKVYVG-KNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTVEGQLTSDERGAHIMN 495
+ K SEV+E V K + + + + + ++ + +L + IM
Sbjct: 1530 EKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMI 1589
Query: 496 STCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKNCSLQTELNKSYDVKNPSPLLM 555
M ++ E + N + + ++++ + + K V +
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEI-----VAKMKESQEKEYQFLKMTAVNETQEKMC 1644
Query: 556 QNQNTRQQMDTPMVSCGN--------EQFLDNSFEK-------------VKRRLDLDIDG 594
+ ++ ++Q +T ++ N Q L + E+ V+ L ++ D
Sbjct: 1645 EIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQ 1704
Query: 595 LQKENCPYVITSGITEQER-----QHLPEKR--YPKGSGFVN-KNKMLGTSSKE---SEE 643
L KEN IT + +QE HL E + K G V+ K + K+ S +
Sbjct: 1705 L-KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSND 1763
Query: 644 LLKSKMLAFEE------MRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEK-- 695
LK++ L +E M + +++ +L +++E+ + +QK++E L+EK
Sbjct: 1764 ALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQ 1823
Query: 696 KAMTAEASELDINNAVELEWRKISDSSLLETML 728
+ E + + V +K+S+ L+ +
Sbjct: 1824 ELKANEHQLITLKKDVNETQKKVSEMEQLKKQI 1856
>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
Length = 757
Score = 40.4 bits (93), Expect = 0.008
Identities = 44/167 (26%), Positives = 80/167 (47%), Gaps = 22/167 (13%)
Query: 574 EQFLDNSFEKVKRRLDLDIDGL----------QKENCPYVITSGITEQERQHLPEK-RYP 622
E L + E+++ + + +ID L + N + + E+ER + EK
Sbjct: 374 ENKLHDELEQIRLKTNQEIDQLRNASREMYERENRNLREARDNAVAEKERAVMAEKDALE 433
Query: 623 KGSGFVNKNK--MLGTSSKESEELLKSKMLAFEEMR-KRLEEQHAQQLSLLIAEQEREQE 679
K +++ + L T SK +E L +SK+ +FE R + L+E+ A+ L+ E E+ Q+
Sbjct: 434 KHDQLLDRYRELQLSTESKVTEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQK 493
Query: 680 RLQKEIEE-------QEKMLKEKKAMTAE-ASELDINNAVELEWRKI 718
+L+ +E EK + E +A +E + LDI +E E +I
Sbjct: 494 KLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 540
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 40.4 bits (93), Expect = 0.008
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 26/166 (15%)
Query: 612 ERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLI 671
ER L ++R + + ++ K + +E + L+ K L +E R+RLEEQ +
Sbjct: 137 ERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQL--QERRRRLEEQRLKAEQRRA 194
Query: 672 AEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQA 731
A +ER++++L+K E E I +V+ W +I + S A
Sbjct: 195 ALEERQRQKLEKNKERYEAA---------------IQRSVKKTWAEIR-----QQRWSWA 234
Query: 732 DSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVT 777
+LH S S G S + S VSA P ++ L+K S T
Sbjct: 235 GALHHS---SPGHKTSGSRCS-VSAVNLPKHVDSIINKRLSKSSAT 276
Score = 32.7 bits (73), Expect = 1.7
Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 13/99 (13%)
Query: 653 EEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQE----------KMLKEKKAMTAEA 702
E +R EEQ A++ + AEQE EQERLQK+ EE E ++ +EK E
Sbjct: 647 EAEARRREEQEAREKAQ--AEQE-EQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQ 703
Query: 703 SELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNS 741
+ +E ++ S + ET Q +N +S
Sbjct: 704 ERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSS 742
Score = 32.7 bits (73), Expect = 1.7
Identities = 24/112 (21%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
Query: 639 KESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAM 698
+ E+ + K A +E ++RL++Q + + E ER++ +K ++QE+ +E++
Sbjct: 652 RREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKR 711
Query: 699 TAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQ 750
E + + V E ++ DS S + + + S G A+Q
Sbjct: 712 LEEIMKRTRKSEVS-ETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQ 762
Score = 32.3 bits (72), Expect = 2.3
Identities = 15/59 (25%), Positives = 32/59 (54%)
Query: 646 KSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASE 704
+ K + E++ + E + ++ E++ +E+ Q E EEQE++ K+K+ A + E
Sbjct: 627 RDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSRE 685
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 40.0 bits (92), Expect = 0.011
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 653 EEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVE 712
E + R+ + QQ + L+ E++R+ + L+K+ EQ ++L EK+A A+ S+ E
Sbjct: 172 ETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISE 231
Query: 713 LEWRKISDSSLLETMLSQADSLHTSNS 739
L+ R SS LE + L S S
Sbjct: 232 LDRR--CHSSALELLQEVIIVLERSES 256
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,996,444
Number of Sequences: 37866
Number of extensions: 1592044
Number of successful extensions: 11936
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 139
Number of HSP's successfully gapped in prelim test: 429
Number of HSP's that attempted gapping in prelim test: 7860
Number of HSP's gapped (non-prelim): 3283
length of query: 991
length of database: 18,247,518
effective HSP length: 112
effective length of query: 879
effective length of database: 14,006,526
effective search space: 12311736354
effective search space used: 12311736354
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.