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Search of human proteins with 189491739
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189491739 nuclear receptor subfamily 2, group C, member 1
isoform a [Homo sapiens]
(603 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189491739 nuclear receptor subfamily 2, group C, member 1 iso... 1209 0.0
gi|189491766 nuclear receptor subfamily 2, group C, member 1 iso... 934 0.0
gi|73808084 nuclear receptor subfamily 2, group C, member 1 isof... 932 0.0
gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Hom... 707 0.0
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 134 2e-31
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 133 5e-31
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens] 132 7e-31
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens] 132 7e-31
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens] 132 7e-31
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens] 132 7e-31
gi|223555953 nuclear receptor subfamily 2, group F, member 2 iso... 131 2e-30
gi|223555951 nuclear receptor subfamily 2, group F, member 2 iso... 131 2e-30
gi|223555949 nuclear receptor subfamily 2, group F, member 2 iso... 131 2e-30
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 131 2e-30
gi|11415052 retinoid X receptor, beta [Homo sapiens] 128 1e-29
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 127 2e-29
gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo sa... 126 5e-29
gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo sa... 126 5e-29
gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo sa... 126 5e-29
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 125 1e-28
gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo sa... 124 3e-28
gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo sa... 124 3e-28
gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo sa... 124 3e-28
gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens] 123 4e-28
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 119 1e-26
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 119 1e-26
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 118 2e-26
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 117 4e-26
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 116 5e-26
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 116 5e-26
>gi|189491739 nuclear receptor subfamily 2, group C, member 1
isoform a [Homo sapiens]
Length = 603
Score = 1209 bits (3127), Expect = 0.0
Identities = 603/603 (100%), Positives = 603/603 (100%)
Query: 1 MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA 60
MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA
Sbjct: 1 MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA 60
Query: 61 RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA 120
RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA
Sbjct: 61 RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA 120
Query: 121 SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ 180
SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ
Sbjct: 121 SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ 180
Query: 181 DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM 240
DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM
Sbjct: 181 DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM 240
Query: 241 FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES 300
FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES
Sbjct: 241 FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES 300
Query: 301 LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN 360
LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN
Sbjct: 301 LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN 360
Query: 361 YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE 420
YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE
Sbjct: 361 YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE 420
Query: 421 NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQDKMSTERRKLLMEHIF 480
NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQDKMSTERRKLLMEHIF
Sbjct: 421 NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQDKMSTERRKLLMEHIF 480
Query: 481 KLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLENMEQIEKFQEKAYVEFQDYITKTY 540
KLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLENMEQIEKFQEKAYVEFQDYITKTY
Sbjct: 481 KLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLENMEQIEKFQEKAYVEFQDYITKTY 540
Query: 541 PDDTYRLSRLLLRLPALRLMNATITEELFFKGLIGNIRIDSVIPHILKMEPADYNSQIIG 600
PDDTYRLSRLLLRLPALRLMNATITEELFFKGLIGNIRIDSVIPHILKMEPADYNSQIIG
Sbjct: 541 PDDTYRLSRLLLRLPALRLMNATITEELFFKGLIGNIRIDSVIPHILKMEPADYNSQIIG 600
Query: 601 HSI 603
HSI
Sbjct: 601 HSI 603
>gi|189491766 nuclear receptor subfamily 2, group C, member 1
isoform c [Homo sapiens]
Length = 483
Score = 934 bits (2415), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA 60
MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA
Sbjct: 1 MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA 60
Query: 61 RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA 120
RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA
Sbjct: 61 RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA 120
Query: 121 SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ 180
SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ
Sbjct: 121 SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ 180
Query: 181 DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM 240
DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM
Sbjct: 181 DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM 240
Query: 241 FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES 300
FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES
Sbjct: 241 FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES 300
Query: 301 LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN 360
LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN
Sbjct: 301 LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN 360
Query: 361 YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE 420
YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE
Sbjct: 361 YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE 420
Query: 421 NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQD 465
NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQD
Sbjct: 421 NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQD 465
>gi|73808084 nuclear receptor subfamily 2, group C, member 1 isoform
b [Homo sapiens]
Length = 467
Score = 932 bits (2409), Expect = 0.0
Identities = 464/464 (100%), Positives = 464/464 (100%)
Query: 1 MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA 60
MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA
Sbjct: 1 MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILA 60
Query: 61 RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA 120
RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA
Sbjct: 61 RQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKA 120
Query: 121 SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ 180
SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ
Sbjct: 121 SGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQ 180
Query: 181 DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM 240
DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM
Sbjct: 181 DSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGM 240
Query: 241 FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES 300
FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES
Sbjct: 241 FMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIES 300
Query: 301 LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN 360
LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN
Sbjct: 301 LSNDDTSLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGMEGSVHLITGDSSIN 360
Query: 361 YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE 420
YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE
Sbjct: 361 YTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQE 420
Query: 421 NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQ 464
NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQ
Sbjct: 421 NSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQ 464
>gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Homo
sapiens]
Length = 615
Score = 707 bits (1826), Expect = 0.0
Identities = 375/601 (62%), Positives = 452/601 (75%), Gaps = 43/601 (7%)
Query: 18 EIVTEQQTGQKIQIVTALDHNTQGKQ-FILTNHDGSTPSKVILARQDSTPGKVFLTTPDA 76
+IVT+QQTGQKIQIVTA+D + KQ FILT+ DG+ KVILA +P+
Sbjct: 43 KIVTDQQTGQKIQIVTAVDASGSPKQQFILTSPDGAGTGKVILA------------SPET 90
Query: 77 AGVNQLFFTTPD-LSAQHLQLLTDNSP--------DQGPNKVFDLCVVCGDKASGRHYGA 127
+ QL FTT D L +Q++TD++ D +V + CVVCGDKASGRHYGA
Sbjct: 91 SSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGKTDVQRPQVVEYCVVCGDKASGRHYGA 150
Query: 128 VTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCER 187
V+CEGCKGFFKRS+RKNL YSCR ++DCIINKHHRNRCQ+CRL++C+ GMK +SVQ ER
Sbjct: 151 VSCEGCKGFFKRSVRKNLTYSCRSNQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSER 210
Query: 188 KPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGMFMNIHPS 247
KP +V REK SNCAASTEKIYIRKDLRSPL ATPTFV D + R TGLLD GM +NI
Sbjct: 211 KPFDVQREKPSNCAASTEKIYIRKDLRSPLIATPTFVADKDGARQTGLLDPGMLVNIQQP 270
Query: 248 GVKTESAVLMTSD-KAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIESLSNDDT 306
++ + VL+ +D KAE+ QG L TLANVVTSLANL ESL+N DT
Sbjct: 271 LIREDGTVLLATDSKAETSQGALGTLANVVTSLANLS---------------ESLNNGDT 315
Query: 307 SLCEFQEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGME----GSVHLITGDSSINYT 362
S + E Q+ +++RAFDTLAKALN +S++ S G++ GS+H+I+ D S
Sbjct: 316 SEIQ-PEDQSASEITRAFDTLAKALNTTDSSSSPSLADGIDTSGGGSIHVISRDQSTPII 374
Query: 363 EKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQENS 422
E EGPLLSD+HV F+LTMPSPMPEYLNVHYI ESASRLLFLSMHWA SIP+FQALGQ+ +
Sbjct: 375 EVEGPLLSDTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPAFQALGQDCN 434
Query: 423 ISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKL 482
SLV+A WNELFTLGLAQC QVM+++TILA VN L NS+Q+DK+S +R K +MEHI+KL
Sbjct: 435 TSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQEDKLSGDRIKQVMEHIWKL 494
Query: 483 QEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPD 542
QEFCNSM KL IDGYEYAYLKAIVLFSPDHP L + QIEKFQEKA +E QDY+ KTY +
Sbjct: 495 QEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTSTSQIEKFQEKAQMELQDYVQKTYSE 554
Query: 543 DTYRLSRLLLRLPALRLMNATITEELFFKGLIGNIRIDSVIPHILKMEPADYNSQIIGHS 602
DTYRL+R+L+RLPALRLM++ ITEELFF GLIGN+ IDS+IP+ILKME A+YN QI G S
Sbjct: 555 DTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIPYILKMETAEYNGQITGAS 614
Query: 603 I 603
+
Sbjct: 615 L 615
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 134 bits (338), Expect = 2e-31
Identities = 60/124 (48%), Positives = 84/124 (67%), Gaps = 2/124 (1%)
Query: 100 NSPDQGPNK-VFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIIN 158
N P P V +C +CGD++SG+HYG +CEGCKGFFKR+IRK+L+Y+CR +KDC+I+
Sbjct: 125 NYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLID 184
Query: 159 KHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAAS-TEKIYIRKDLRSPL 217
K RNRCQYCR Q+C+ GMK+++VQ ER+ E + CA S E + + + L + L
Sbjct: 185 KRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAEL 244
Query: 218 TATP 221
P
Sbjct: 245 AVEP 248
Score = 102 bits (254), Expect = 1e-21
Identities = 63/196 (32%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Query: 393 IGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILA 452
I +A + LF + WA IP F L E+ + L++A WNEL + + +LA
Sbjct: 269 ICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLA 328
Query: 453 TFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDH 512
T ++ +S + + ++L E + K+++ + +D E L+AIVLF+PD
Sbjct: 329 TGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD-------MQMDKSELGCLRAIVLFNPDA 381
Query: 513 PSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKG 572
L N ++E +EK Y + Y + YP+ R ++LLLRLPALR + E LFF
Sbjct: 382 KGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFK 441
Query: 573 LIGNIRIDSVIPHILK 588
LIG+ ID+ + +L+
Sbjct: 442 LIGDTPIDTFLMEMLE 457
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 133 bits (334), Expect = 5e-31
Identities = 75/200 (37%), Positives = 114/200 (57%), Gaps = 6/200 (3%)
Query: 388 LNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNV 447
+ + I E A+RLLF ++ WA +IP F L + +SL++ W+ELF L AQC ++V
Sbjct: 214 MGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHV 273
Query: 448 ATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVL 507
A +LA L MS +R M+HI QE + L +D EY+ LKAIVL
Sbjct: 274 APLLAAA------GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 327
Query: 508 FSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEE 567
F+ D L + IE QEK+ ++Y+ YP+ R +LLLRLP+LR +++++ E+
Sbjct: 328 FTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQ 387
Query: 568 LFFKGLIGNIRIDSVIPHIL 587
LFF L+G I+++I +L
Sbjct: 388 LFFVRLVGKTPIETLIRDML 407
Score = 125 bits (313), Expect = 1e-28
Identities = 50/88 (56%), Positives = 70/88 (79%)
Query: 102 PDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHH 161
P G ++ CVVCGDK+SG+HYG TCEGCK FFKRS+R+NL Y+CR +++C I++HH
Sbjct: 75 PGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHH 134
Query: 162 RNRCQYCRLQRCIAFGMKQDSVQCERKP 189
RN+CQYCRL++C+ GM++++VQ R P
Sbjct: 135 RNQCQYCRLKKCLKVGMRREAVQRGRMP 162
>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
Length = 468
Score = 132 bits (333), Expect = 7e-31
Identities = 129/481 (26%), Positives = 217/481 (45%), Gaps = 71/481 (14%)
Query: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
Query: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 78 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 131
Query: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLG 283
+ + GL D +++ H P G K +SAV S ++ S G
Sbjct: 132 NISANGLTELHDDLSNYIDGHTPEGSKADSAV-------------SSFYLDIQPSPDQSG 178
Query: 284 KTKDLSQNSNEMSMIESLSNDDTSLCEFQEMQTNGDVSRA-FDTLAKALNPGESTACQSS 342
D++ E + ++ C F +T+ VS A + LA+ ++ CQ
Sbjct: 179 --LDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQY- 235
Query: 343 VAGMEGSVHLITGDSSI-----NYTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESA 397
+ + IT + + NY K+ ++ A ++T + Y+ E A
Sbjct: 236 ---LREELQQITWQTFLQEEIENYQNKQREVMWQL-CAIKITEA--------IQYVVEFA 283
Query: 398 SRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNC 457
R I F L Q + I L+KA E+ + + + + N N
Sbjct: 284 KR-----------IDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQN---------NT 323
Query: 458 LHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLEN 517
++ + + + I + EF S+ + + E A A VL S D L+
Sbjct: 324 VYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQE 383
Query: 518 MEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELF-FKGLIGN 576
+IEK Q+K + Q + K + +D L++L+ ++ LR + TE+L FK + +
Sbjct: 384 KVKIEKLQQKIQLALQHVLQKNHREDGI-LTKLICKVSTLRALCGRHTEKLMAFKAIYPD 442
Query: 577 I 577
I
Sbjct: 443 I 443
>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
Length = 548
Score = 132 bits (333), Expect = 7e-31
Identities = 129/481 (26%), Positives = 217/481 (45%), Gaps = 71/481 (14%)
Query: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 98 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
Query: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 158 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 211
Query: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLG 283
+ + GL D +++ H P G K +SAV S ++ S G
Sbjct: 212 NISANGLTELHDDLSNYIDGHTPEGSKADSAV-------------SSFYLDIQPSPDQSG 258
Query: 284 KTKDLSQNSNEMSMIESLSNDDTSLCEFQEMQTNGDVSRA-FDTLAKALNPGESTACQSS 342
D++ E + ++ C F +T+ VS A + LA+ ++ CQ
Sbjct: 259 --LDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQY- 315
Query: 343 VAGMEGSVHLITGDSSI-----NYTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESA 397
+ + IT + + NY K+ ++ A ++T + Y+ E A
Sbjct: 316 ---LREELQQITWQTFLQEEIENYQNKQREVMWQL-CAIKITEA--------IQYVVEFA 363
Query: 398 SRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNC 457
R I F L Q + I L+KA E+ + + + + N N
Sbjct: 364 KR-----------IDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQN---------NT 403
Query: 458 LHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLEN 517
++ + + + I + EF S+ + + E A A VL S D L+
Sbjct: 404 VYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQE 463
Query: 518 MEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELF-FKGLIGN 576
+IEK Q+K + Q + K + +D L++L+ ++ LR + TE+L FK + +
Sbjct: 464 KVKIEKLQQKIQLALQHVLQKNHREDGI-LTKLICKVSTLRALCGRHTEKLMAFKAIYPD 522
Query: 577 I 577
I
Sbjct: 523 I 523
>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
Length = 556
Score = 132 bits (333), Expect = 7e-31
Identities = 129/481 (26%), Positives = 217/481 (45%), Gaps = 71/481 (14%)
Query: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 106 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 165
Query: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 166 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 219
Query: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLG 283
+ + GL D +++ H P G K +SAV S ++ S G
Sbjct: 220 NISANGLTELHDDLSNYIDGHTPEGSKADSAV-------------SSFYLDIQPSPDQSG 266
Query: 284 KTKDLSQNSNEMSMIESLSNDDTSLCEFQEMQTNGDVSRA-FDTLAKALNPGESTACQSS 342
D++ E + ++ C F +T+ VS A + LA+ ++ CQ
Sbjct: 267 --LDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQY- 323
Query: 343 VAGMEGSVHLITGDSSI-----NYTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESA 397
+ + IT + + NY K+ ++ A ++T + Y+ E A
Sbjct: 324 ---LREELQQITWQTFLQEEIENYQNKQREVMWQL-CAIKITEA--------IQYVVEFA 371
Query: 398 SRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNC 457
R I F L Q + I L+KA E+ + + + + N N
Sbjct: 372 KR-----------IDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQN---------NT 411
Query: 458 LHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLEN 517
++ + + + I + EF S+ + + E A A VL S D L+
Sbjct: 412 VYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQE 471
Query: 518 MEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELF-FKGLIGN 576
+IEK Q+K + Q + K + +D L++L+ ++ LR + TE+L FK + +
Sbjct: 472 KVKIEKLQQKIQLALQHVLQKNHREDGI-LTKLICKVSTLRALCGRHTEKLMAFKAIYPD 530
Query: 577 I 577
I
Sbjct: 531 I 531
>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
Length = 523
Score = 132 bits (333), Expect = 7e-31
Identities = 129/481 (26%), Positives = 217/481 (45%), Gaps = 71/481 (14%)
Query: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
Query: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 133 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 186
Query: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLG 283
+ + GL D +++ H P G K +SAV S ++ S G
Sbjct: 187 NISANGLTELHDDLSNYIDGHTPEGSKADSAV-------------SSFYLDIQPSPDQSG 233
Query: 284 KTKDLSQNSNEMSMIESLSNDDTSLCEFQEMQTNGDVSRA-FDTLAKALNPGESTACQSS 342
D++ E + ++ C F +T+ VS A + LA+ ++ CQ
Sbjct: 234 --LDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQY- 290
Query: 343 VAGMEGSVHLITGDSSI-----NYTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESA 397
+ + IT + + NY K+ ++ A ++T + Y+ E A
Sbjct: 291 ---LREELQQITWQTFLQEEIENYQNKQREVMWQL-CAIKITEA--------IQYVVEFA 338
Query: 398 SRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNC 457
R I F L Q + I L+KA E+ + + + + N N
Sbjct: 339 KR-----------IDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQN---------NT 378
Query: 458 LHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLEN 517
++ + + + I + EF S+ + + E A A VL S D L+
Sbjct: 379 VYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQE 438
Query: 518 MEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELF-FKGLIGN 576
+IEK Q+K + Q + K + +D L++L+ ++ LR + TE+L FK + +
Sbjct: 439 KVKIEKLQQKIQLALQHVLQKNHREDGI-LTKLICKVSTLRALCGRHTEKLMAFKAIYPD 497
Query: 577 I 577
I
Sbjct: 498 I 498
>gi|223555953 nuclear receptor subfamily 2, group F, member 2
isoform c [Homo sapiens]
Length = 261
Score = 131 bits (330), Expect = 2e-30
Identities = 72/200 (36%), Positives = 115/200 (57%), Gaps = 6/200 (3%)
Query: 388 LNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNV 447
+ + I E A+R+LF ++ WA +IP F L + ++L++ W+ELF L AQC ++V
Sbjct: 54 MGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHV 113
Query: 448 ATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVL 507
A +LA L MS +R M+HI QE + L +D EY+ LKAIVL
Sbjct: 114 APLLAAA------GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 167
Query: 508 FSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEE 567
F+ D L ++ +E QEK+ ++Y+ YP+ R +LLLRLP+LR +++++ E+
Sbjct: 168 FTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQ 227
Query: 568 LFFKGLIGNIRIDSVIPHIL 587
LFF L+G I+++I +L
Sbjct: 228 LFFVRLVGKTPIETLIRDML 247
>gi|223555951 nuclear receptor subfamily 2, group F, member 2
isoform c [Homo sapiens]
Length = 261
Score = 131 bits (330), Expect = 2e-30
Identities = 72/200 (36%), Positives = 115/200 (57%), Gaps = 6/200 (3%)
Query: 388 LNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNV 447
+ + I E A+R+LF ++ WA +IP F L + ++L++ W+ELF L AQC ++V
Sbjct: 54 MGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHV 113
Query: 448 ATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVL 507
A +LA L MS +R M+HI QE + L +D EY+ LKAIVL
Sbjct: 114 APLLAAA------GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 167
Query: 508 FSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEE 567
F+ D L ++ +E QEK+ ++Y+ YP+ R +LLLRLP+LR +++++ E+
Sbjct: 168 FTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQ 227
Query: 568 LFFKGLIGNIRIDSVIPHIL 587
LFF L+G I+++I +L
Sbjct: 228 LFFVRLVGKTPIETLIRDML 247
>gi|223555949 nuclear receptor subfamily 2, group F, member 2
isoform b [Homo sapiens]
Length = 281
Score = 131 bits (330), Expect = 2e-30
Identities = 72/200 (36%), Positives = 115/200 (57%), Gaps = 6/200 (3%)
Query: 388 LNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNV 447
+ + I E A+R+LF ++ WA +IP F L + ++L++ W+ELF L AQC ++V
Sbjct: 74 MGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHV 133
Query: 448 ATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVL 507
A +LA L MS +R M+HI QE + L +D EY+ LKAIVL
Sbjct: 134 APLLAAA------GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 187
Query: 508 FSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEE 567
F+ D L ++ +E QEK+ ++Y+ YP+ R +LLLRLP+LR +++++ E+
Sbjct: 188 FTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQ 247
Query: 568 LFFKGLIGNIRIDSVIPHIL 587
LFF L+G I+++I +L
Sbjct: 248 LFFVRLVGKTPIETLIRDML 267
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 131 bits (330), Expect = 2e-30
Identities = 72/200 (36%), Positives = 115/200 (57%), Gaps = 6/200 (3%)
Query: 388 LNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNV 447
+ + I E A+R+LF ++ WA +IP F L + ++L++ W+ELF L AQC ++V
Sbjct: 207 MGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHV 266
Query: 448 ATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVL 507
A +LA L MS +R M+HI QE + L +D EY+ LKAIVL
Sbjct: 267 APLLAAA------GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 320
Query: 508 FSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEE 567
F+ D L ++ +E QEK+ ++Y+ YP+ R +LLLRLP+LR +++++ E+
Sbjct: 321 FTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQ 380
Query: 568 LFFKGLIGNIRIDSVIPHIL 587
LFF L+G I+++I +L
Sbjct: 381 LFFVRLVGKTPIETLIRDML 400
Score = 122 bits (307), Expect = 7e-28
Identities = 48/77 (62%), Positives = 66/77 (85%)
Query: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
CVVCGDK+SG+HYG TCEGCK FFKRS+R+NL Y+CR +++C I++HHRN+CQYCRL++
Sbjct: 79 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKK 138
Query: 173 CIAFGMKQDSVQCERKP 189
C+ GM++++VQ R P
Sbjct: 139 CLKVGMRREAVQRGRMP 155
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 128 bits (322), Expect = 1e-29
Identities = 53/87 (60%), Positives = 69/87 (79%)
Query: 102 PDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHH 161
P GP LC +CGD++SG+HYG +CEGCKGFFKR+IRK+L YSCR +KDC ++K
Sbjct: 194 PPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQ 253
Query: 162 RNRCQYCRLQRCIAFGMKQDSVQCERK 188
RNRCQYCR Q+C+A GMK+++VQ ER+
Sbjct: 254 RNRCQYCRYQKCLATGMKREAVQEERQ 280
Score = 103 bits (258), Expect = 3e-22
Identities = 62/196 (31%), Positives = 103/196 (52%), Gaps = 7/196 (3%)
Query: 393 IGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILA 452
I ++A + LF + WA IP F +L ++ + L++A WNEL + + +LA
Sbjct: 339 ICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLA 398
Query: 453 TFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDH 512
T ++ NS + ++L E + K+++ + +D E L+AI+LF+PD
Sbjct: 399 TGLHVHRNSAHSAGVGAIFDRVLTELVSKMRD-------MRMDKTELGCLRAIILFNPDA 451
Query: 513 PSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKG 572
L N ++E +EK Y + Y + YP+ R ++LLLRLPALR + E LFF
Sbjct: 452 KGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFK 511
Query: 573 LIGNIRIDSVIPHILK 588
LIG+ ID+ + +L+
Sbjct: 512 LIGDTPIDTFLMEMLE 527
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 127 bits (320), Expect = 2e-29
Identities = 55/119 (46%), Positives = 84/119 (70%), Gaps = 1/119 (0%)
Query: 112 LCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQ 171
+C +CGD++SG+HYG +CEGCKGFFKR++RK+L Y+CR +KDC+I+K RNRCQYCR Q
Sbjct: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193
Query: 172 RCIAFGMKQDSVQCERKPIEVSREKS-SNCAASTEKIYIRKDLRSPLTATPTFVTDSES 229
+C+A GMK+++VQ ER+ + E + +++ E + + + L + L P T E+
Sbjct: 194 KCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEA 252
Score = 103 bits (258), Expect = 3e-22
Identities = 63/196 (32%), Positives = 101/196 (51%), Gaps = 7/196 (3%)
Query: 393 IGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILA 452
I ++A + LF + WA IP F L ++ + L++A WNEL + + +LA
Sbjct: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA 327
Query: 453 TFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDH 512
T ++ NS + ++L E + K+++ + +D E L+AIVLF+PD
Sbjct: 328 TGLHVHRNSAHSAGVGAIFDRVLTELVSKMRD-------MQMDKTELGCLRAIVLFNPDS 380
Query: 513 PSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKG 572
L N ++E +EK Y + Y YP+ R ++LLLRLPALR + E LFF
Sbjct: 381 KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFK 440
Query: 573 LIGNIRIDSVIPHILK 588
LIG+ ID+ + +L+
Sbjct: 441 LIGDTPIDTFLMEMLE 456
>gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo
sapiens]
Length = 417
Score = 126 bits (317), Expect = 5e-29
Identities = 59/143 (41%), Positives = 92/143 (64%), Gaps = 10/143 (6%)
Query: 89 LSAQHLQLLT---DNSPDQGPNK-------VFDLCVVCGDKASGRHYGAVTCEGCKGFFK 138
L +++Q+LT D SP +G N V LC +CGD+A+G+HYGA +C+GCKGFF+
Sbjct: 26 LEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR 85
Query: 139 RSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSS 198
RS+RKN +YSCR S+ C+++K RN+C+YCRL++C GMK+++VQ ER I R
Sbjct: 86 RSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYE 145
Query: 199 NCAASTEKIYIRKDLRSPLTATP 221
+ + + ++ ++ S +P
Sbjct: 146 DSSLPSINALLQAEVLSRQITSP 168
Score = 84.3 bits (207), Expect = 3e-16
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 7/193 (3%)
Query: 395 ESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATF 454
ES L + + WA IP+F L ++ ++L++A+ E LG + V +L
Sbjct: 189 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 248
Query: 455 VNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPS 514
+ + +MS ++L E + QE L ID EYAYLKAI+ F PD
Sbjct: 249 YIVPRHCPELAEMSRVSIRILDELVLPFQE-------LQIDDNEYAYLKAIIFFDPDAKG 301
Query: 515 LENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKGLI 574
L + +I++ + + V +DYI D R LLL LP L+ + + E++ F L
Sbjct: 302 LSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLF 361
Query: 575 GNIRIDSVIPHIL 587
G +ID+++ +L
Sbjct: 362 GMAKIDNLLQEML 374
>gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo
sapiens]
Length = 464
Score = 126 bits (317), Expect = 5e-29
Identities = 59/143 (41%), Positives = 92/143 (64%), Gaps = 10/143 (6%)
Query: 89 LSAQHLQLLT---DNSPDQGPNK-------VFDLCVVCGDKASGRHYGAVTCEGCKGFFK 138
L +++Q+LT D SP +G N V LC +CGD+A+G+HYGA +C+GCKGFF+
Sbjct: 26 LEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR 85
Query: 139 RSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSS 198
RS+RKN +YSCR S+ C+++K RN+C+YCRL++C GMK+++VQ ER I R
Sbjct: 86 RSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYE 145
Query: 199 NCAASTEKIYIRKDLRSPLTATP 221
+ + + ++ ++ S +P
Sbjct: 146 DSSLPSINALLQAEVLSRQITSP 168
Score = 84.3 bits (207), Expect = 3e-16
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 7/193 (3%)
Query: 395 ESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATF 454
ES L + + WA IP+F L ++ ++L++A+ E LG + V +L
Sbjct: 189 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 248
Query: 455 VNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPS 514
+ + +MS ++L E + QE L ID EYAYLKAI+ F PD
Sbjct: 249 YIVPRHCPELAEMSRVSIRILDELVLPFQE-------LQIDDNEYAYLKAIIFFDPDAKG 301
Query: 515 LENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKGLI 574
L + +I++ + + V +DYI D R LLL LP L+ + + E++ F L
Sbjct: 302 LSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLF 361
Query: 575 GNIRIDSVIPHIL 587
G +ID+++ +L
Sbjct: 362 GMAKIDNLLQEML 374
>gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo
sapiens]
Length = 474
Score = 126 bits (317), Expect = 5e-29
Identities = 59/143 (41%), Positives = 92/143 (64%), Gaps = 10/143 (6%)
Query: 89 LSAQHLQLLT---DNSPDQGPNK-------VFDLCVVCGDKASGRHYGAVTCEGCKGFFK 138
L +++Q+LT D SP +G N V LC +CGD+A+G+HYGA +C+GCKGFF+
Sbjct: 26 LEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR 85
Query: 139 RSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSS 198
RS+RKN +YSCR S+ C+++K RN+C+YCRL++C GMK+++VQ ER I R
Sbjct: 86 RSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYE 145
Query: 199 NCAASTEKIYIRKDLRSPLTATP 221
+ + + ++ ++ S +P
Sbjct: 146 DSSLPSINALLQAEVLSRQITSP 168
Score = 84.3 bits (207), Expect = 3e-16
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 7/193 (3%)
Query: 395 ESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATF 454
ES L + + WA IP+F L ++ ++L++A+ E LG + V +L
Sbjct: 189 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 248
Query: 455 VNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPS 514
+ + +MS ++L E + QE L ID EYAYLKAI+ F PD
Sbjct: 249 YIVPRHCPELAEMSRVSIRILDELVLPFQE-------LQIDDNEYAYLKAIIFFDPDAKG 301
Query: 515 LENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKGLI 574
L + +I++ + + V +DYI D R LLL LP L+ + + E++ F L
Sbjct: 302 LSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLF 361
Query: 575 GNIRIDSVIPHIL 587
G +ID+++ +L
Sbjct: 362 GMAKIDNLLQEML 374
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 125 bits (313), Expect = 1e-28
Identities = 72/200 (36%), Positives = 107/200 (53%), Gaps = 6/200 (3%)
Query: 388 LNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNV 447
L + + E A+RLLF ++ WA P F L + ++L++ W+ELF L AQ ++
Sbjct: 197 LGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHT 256
Query: 448 ATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVL 507
A +LA L M+ ER M+ + QE + + +L +D EY LKAI L
Sbjct: 257 APLLAAA------GLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIAL 310
Query: 508 FSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEE 567
F+PD L + +E QEKA V +Y+ YP R RLLLRLPALR + A++ +
Sbjct: 311 FTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQ 370
Query: 568 LFFKGLIGNIRIDSVIPHIL 587
LFF L+G I+++I +L
Sbjct: 371 LFFMRLVGKTPIETLIRDML 390
Score = 124 bits (310), Expect = 3e-28
Identities = 50/77 (64%), Positives = 65/77 (84%)
Query: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
CVVCGDK+SG+HYG TCEGCK FFKRSIR+NL Y+CR ++DC I++HHRN+CQYCRL++
Sbjct: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
Query: 173 CIAFGMKQDSVQCERKP 189
C GM++++VQ R P
Sbjct: 116 CFRVGMRKEAVQRGRIP 132
>gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo
sapiens]
Length = 395
Score = 124 bits (310), Expect = 3e-28
Identities = 55/130 (42%), Positives = 84/130 (64%), Gaps = 7/130 (5%)
Query: 99 DNSPDQGPNK-------VFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRG 151
D SP +G N V LC +CGD+A+G+HYGA +C+GCKGFF+RS+RKN +YSCR
Sbjct: 17 DTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRF 76
Query: 152 SKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRK 211
S+ C+++K RN+C+YCRL++C GMK+++VQ ER I R + + + ++
Sbjct: 77 SRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQA 136
Query: 212 DLRSPLTATP 221
++ S +P
Sbjct: 137 EVLSRQITSP 146
Score = 84.3 bits (207), Expect = 3e-16
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 7/193 (3%)
Query: 395 ESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATF 454
ES L + + WA IP+F L ++ ++L++A+ E LG + V +L
Sbjct: 167 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 226
Query: 455 VNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPS 514
+ + +MS ++L E + QE L ID EYAYLKAI+ F PD
Sbjct: 227 YIVPRHCPELAEMSRVSIRILDELVLPFQE-------LQIDDNEYAYLKAIIFFDPDAKG 279
Query: 515 LENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKGLI 574
L + +I++ + + V +DYI D R LLL LP L+ + + E++ F L
Sbjct: 280 LSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLF 339
Query: 575 GNIRIDSVIPHIL 587
G +ID+++ +L
Sbjct: 340 GMAKIDNLLQEML 352
>gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo
sapiens]
Length = 442
Score = 124 bits (310), Expect = 3e-28
Identities = 55/130 (42%), Positives = 84/130 (64%), Gaps = 7/130 (5%)
Query: 99 DNSPDQGPNK-------VFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRG 151
D SP +G N V LC +CGD+A+G+HYGA +C+GCKGFF+RS+RKN +YSCR
Sbjct: 17 DTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRF 76
Query: 152 SKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRK 211
S+ C+++K RN+C+YCRL++C GMK+++VQ ER I R + + + ++
Sbjct: 77 SRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQA 136
Query: 212 DLRSPLTATP 221
++ S +P
Sbjct: 137 EVLSRQITSP 146
Score = 84.3 bits (207), Expect = 3e-16
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 7/193 (3%)
Query: 395 ESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATF 454
ES L + + WA IP+F L ++ ++L++A+ E LG + V +L
Sbjct: 167 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 226
Query: 455 VNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPS 514
+ + +MS ++L E + QE L ID EYAYLKAI+ F PD
Sbjct: 227 YIVPRHCPELAEMSRVSIRILDELVLPFQE-------LQIDDNEYAYLKAIIFFDPDAKG 279
Query: 515 LENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKGLI 574
L + +I++ + + V +DYI D R LLL LP L+ + + E++ F L
Sbjct: 280 LSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLF 339
Query: 575 GNIRIDSVIPHIL 587
G +ID+++ +L
Sbjct: 340 GMAKIDNLLQEML 352
>gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo
sapiens]
Length = 452
Score = 124 bits (310), Expect = 3e-28
Identities = 55/130 (42%), Positives = 84/130 (64%), Gaps = 7/130 (5%)
Query: 99 DNSPDQGPNK-------VFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRG 151
D SP +G N V LC +CGD+A+G+HYGA +C+GCKGFF+RS+RKN +YSCR
Sbjct: 17 DTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRF 76
Query: 152 SKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRK 211
S+ C+++K RN+C+YCRL++C GMK+++VQ ER I R + + + ++
Sbjct: 77 SRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQA 136
Query: 212 DLRSPLTATP 221
++ S +P
Sbjct: 137 EVLSRQITSP 146
Score = 84.3 bits (207), Expect = 3e-16
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 7/193 (3%)
Query: 395 ESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATF 454
ES L + + WA IP+F L ++ ++L++A+ E LG + V +L
Sbjct: 167 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 226
Query: 455 VNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPS 514
+ + +MS ++L E + QE L ID EYAYLKAI+ F PD
Sbjct: 227 YIVPRHCPELAEMSRVSIRILDELVLPFQE-------LQIDDNEYAYLKAIIFFDPDAKG 279
Query: 515 LENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKGLI 574
L + +I++ + + V +DYI D R LLL LP L+ + + E++ F L
Sbjct: 280 LSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLF 339
Query: 575 GNIRIDSVIPHIL 587
G +ID+++ +L
Sbjct: 340 GMAKIDNLLQEML 352
>gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
Length = 445
Score = 123 bits (309), Expect = 4e-28
Identities = 56/114 (49%), Positives = 80/114 (70%), Gaps = 6/114 (5%)
Query: 81 QLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRS 140
Q+ + + D SA + N+ D G N LC +CGD+A+G+HYGA +C+GCKGFF+RS
Sbjct: 23 QILYNSSDSSAPETSM---NTTDNGVNC---LCAICGDRATGKHYGASSCDGCKGFFRRS 76
Query: 141 IRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSR 194
IRK+ VYSCR S+ C+++K RN+C+YCRL++C GMK+++VQ ER I R
Sbjct: 77 IRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRR 130
Score = 77.8 bits (190), Expect = 3e-14
Identities = 57/194 (29%), Positives = 97/194 (50%), Gaps = 10/194 (5%)
Query: 395 ESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATF 454
ES + L + + WA IP+F L ++ ++L++A+ E LG + + M IL
Sbjct: 178 ESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATK--RSMMYKDILLLG 235
Query: 455 VN-CLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHP 513
N +H + + ++S ++L E + QE + ID EYA LKAIV F PD
Sbjct: 236 NNYVIHRNSCEVEISRVANRVLDELVRPFQE-------IQIDDNEYACLKAIVFFDPDAK 288
Query: 514 SLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELFFKGL 573
L + +I+ + + + +DYI D R LLL LP L+ + + E++ F L
Sbjct: 289 GLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKL 348
Query: 574 IGNIRIDSVIPHIL 587
G ++ID+++ +L
Sbjct: 349 FGMVKIDNLLQEML 362
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 119 bits (297), Expect = 1e-26
Identities = 54/94 (57%), Positives = 69/94 (73%), Gaps = 2/94 (2%)
Query: 106 PNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRC 165
P +V+ C VC DK+SG HYG +CEGCKGFF+RSI+KN+VY+C K+CIINK RNRC
Sbjct: 72 PPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRC 131
Query: 166 QYCRLQRCIAFGMKQDSVQCER--KPIEVSREKS 197
QYCRLQ+C GM +++V+ +R K EV E S
Sbjct: 132 QYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGS 165
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 119 bits (297), Expect = 1e-26
Identities = 54/94 (57%), Positives = 69/94 (73%), Gaps = 2/94 (2%)
Query: 106 PNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRC 165
P +V+ C VC DK+SG HYG +CEGCKGFF+RSI+KN+VY+C K+CIINK RNRC
Sbjct: 83 PPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRC 142
Query: 166 QYCRLQRCIAFGMKQDSVQCER--KPIEVSREKS 197
QYCRLQ+C GM +++V+ +R K EV E S
Sbjct: 143 QYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGS 176
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 118 bits (295), Expect = 2e-26
Identities = 52/104 (50%), Positives = 73/104 (70%), Gaps = 2/104 (1%)
Query: 106 PNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRC 165
P +V+ C VC DK+SG HYG CEGCKGFF+RSI+KN++Y+C K+C+INK RNRC
Sbjct: 74 PPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRC 133
Query: 166 QYCRLQRCIAFGMKQDSVQCER--KPIEVSREKSSNCAASTEKI 207
QYCRLQ+C GM ++SV+ +R K E S+++ + T ++
Sbjct: 134 QYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAEL 177
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 117 bits (292), Expect = 4e-26
Identities = 65/147 (44%), Positives = 86/147 (58%), Gaps = 11/147 (7%)
Query: 64 STPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGP-NKVFDLCVVCGDKASG 122
STP L TP G N T S + + + P P +++ C VC DK+SG
Sbjct: 41 STP----LRTPLWNGSNHSIETQSSSSEE----IVPSPPSPPPLPRIYKPCFVCQDKSSG 92
Query: 123 RHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDS 182
HYG CEGCKGFF+RSI+KN+VY+C K+CIINK RNRCQYCRLQ+C GM ++S
Sbjct: 93 YHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKES 152
Query: 183 VQCER--KPIEVSREKSSNCAASTEKI 207
V+ +R K EV + + S T ++
Sbjct: 153 VRNDRNKKKKEVPKPECSESYTLTPEV 179
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 116 bits (291), Expect = 5e-26
Identities = 53/102 (51%), Positives = 71/102 (69%), Gaps = 2/102 (1%)
Query: 108 KVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQY 167
+++ C VC DK+SG HYG CEGCKGFF+RSI+KN+VY+C K+CIINK RNRCQY
Sbjct: 83 RIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQY 142
Query: 168 CRLQRCIAFGMKQDSVQCER--KPIEVSREKSSNCAASTEKI 207
CRLQ+C GM ++SV+ +R K EV + + S T ++
Sbjct: 143 CRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEV 184
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 116 bits (291), Expect = 5e-26
Identities = 53/102 (51%), Positives = 71/102 (69%), Gaps = 2/102 (1%)
Query: 108 KVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQY 167
+++ C VC DK+SG HYG CEGCKGFF+RSI+KN+VY+C K+CIINK RNRCQY
Sbjct: 83 RIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQY 142
Query: 168 CRLQRCIAFGMKQDSVQCER--KPIEVSREKSSNCAASTEKI 207
CRLQ+C GM ++SV+ +R K EV + + S T ++
Sbjct: 143 CRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEV 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,540,879
Number of Sequences: 37866
Number of extensions: 933441
Number of successful extensions: 2697
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2364
Number of HSP's gapped (non-prelim): 277
length of query: 603
length of database: 18,247,518
effective HSP length: 108
effective length of query: 495
effective length of database: 14,157,990
effective search space: 7008205050
effective search space used: 7008205050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.