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Search of human proteins with 189083830
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189083830 inhibitor of growth family, member 4 isoform 5
[Homo sapiens]
(225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189083830 inhibitor of growth family, member 4 isoform 5 [Hom... 463 e-131
gi|189083821 inhibitor of growth family, member 4 isoform 9 [Hom... 448 e-126
gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo... 439 e-124
gi|189083826 inhibitor of growth family, member 4 isoform 3 [Hom... 435 e-122
gi|189083828 inhibitor of growth family, member 4 isoform 4 [Hom... 434 e-122
gi|18644730 inhibitor of growth family, member 5 [Homo sapiens] 298 3e-81
gi|189083832 inhibitor of growth family, member 4 isoform 6 [Hom... 265 2e-71
gi|38201667 inhibitor of growth family, member 1 isoform A [Homo... 152 2e-37
gi|38201663 inhibitor of growth family, member 1 isoform C [Homo... 150 8e-37
gi|38201661 inhibitor of growth family, member 1 isoform D [Homo... 150 8e-37
gi|38201665 inhibitor of growth family, member 1 isoform B [Homo... 146 1e-35
gi|4504695 inhibitor of growth family, member 2 [Homo sapiens] 140 1e-33
gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo... 115 2e-26
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 50 2e-06
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 48 6e-06
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 48 6e-06
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens] 45 7e-05
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens] 45 7e-05
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 42 4e-04
gi|35493853 otoferlin isoform c [Homo sapiens] 41 7e-04
gi|35493868 otoferlin isoform b [Homo sapiens] 41 7e-04
gi|35493860 otoferlin isoform d [Homo sapiens] 41 7e-04
gi|34740331 otoferlin isoform a [Homo sapiens] 41 7e-04
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 41 0.001
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 41 0.001
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 40 0.001
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 40 0.002
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 40 0.002
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 39 0.003
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 39 0.003
>gi|189083830 inhibitor of growth family, member 4 isoform 5 [Homo
sapiens]
Length = 225
Score = 463 bits (1192), Expect = e-131
Identities = 225/225 (100%), Positives = 225/225 (100%)
Query: 1 MAAGMYLEHYLDNLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQ 60
MAAGMYLEHYLDNLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQ
Sbjct: 1 MAAGMYLEHYLDNLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQ 60
Query: 61 LAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARAR 120
LAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARAR
Sbjct: 61 LAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARAR 120
Query: 121 SKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQV 180
SKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQV
Sbjct: 121 SKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQV 180
Query: 181 SYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK 225
SYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK
Sbjct: 181 SYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK 225
>gi|189083821 inhibitor of growth family, member 4 isoform 9 [Homo
sapiens]
Length = 249
Score = 448 bits (1152), Expect = e-126
Identities = 224/249 (89%), Positives = 225/249 (90%), Gaps = 24/249 (9%)
Query: 1 MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36
MAAGMYLEHYLD+ LKAEIDKLATEYMSSARSLSSEE
Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
Query: 37 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96
KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
Query: 97 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 156
YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180
Query: 157 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216
VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240
Query: 217 RCSQERKKK 225
RCSQERKKK
Sbjct: 241 RCSQERKKK 249
>gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo
sapiens]
Length = 248
Score = 439 bits (1129), Expect = e-124
Identities = 222/249 (89%), Positives = 223/249 (89%), Gaps = 25/249 (10%)
Query: 1 MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36
MAAGMYLEHYLD+ LKAEIDKLATEYMSSARSLSSEE
Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
Query: 37 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96
KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
Query: 97 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 156
YDSSSSKGKK RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSKGKKS-RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 179
Query: 157 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216
VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 180 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 239
Query: 217 RCSQERKKK 225
RCSQERKKK
Sbjct: 240 RCSQERKKK 248
>gi|189083826 inhibitor of growth family, member 4 isoform 3 [Homo
sapiens]
Length = 246
Score = 435 bits (1118), Expect = e-122
Identities = 220/249 (88%), Positives = 222/249 (89%), Gaps = 27/249 (10%)
Query: 1 MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36
MAAGMYLEHYLD+ LKAEIDKLATEYMSSARSLSSEE
Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
Query: 37 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96
KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
Query: 97 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 156
YDSSSSK +GRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSK---EGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 177
Query: 157 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216
VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 178 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 237
Query: 217 RCSQERKKK 225
RCSQERKKK
Sbjct: 238 RCSQERKKK 246
>gi|189083828 inhibitor of growth family, member 4 isoform 4 [Homo
sapiens]
Length = 245
Score = 434 bits (1116), Expect = e-122
Identities = 220/249 (88%), Positives = 221/249 (88%), Gaps = 28/249 (11%)
Query: 1 MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36
MAAGMYLEHYLD+ LKAEIDKLATEYMSSARSLSSEE
Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
Query: 37 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96
KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
Query: 97 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 156
YDSSSSKG RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSKG----RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 176
Query: 157 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216
VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 177 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 236
Query: 217 RCSQERKKK 225
RCSQERKKK
Sbjct: 237 RCSQERKKK 245
>gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]
Length = 240
Score = 298 bits (763), Expect = 3e-81
Identities = 151/249 (60%), Positives = 179/249 (71%), Gaps = 34/249 (13%)
Query: 1 MAAGMYLEHYLDNL------------------------KAEIDKLATEYMSSARSLSSEE 36
MA MYLEHYLD++ KAEID LA EY+S+ ++LS ++
Sbjct: 1 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 60
Query: 37 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96
++ L++IQ AY KCKE+ DDKVQLAMQTYEMVDKHIRRLD DLARFEADLK+K +E SD
Sbjct: 61 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD 119
Query: 97 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 156
++SS +G KKGR QKEK+ +R R + + S+E+ PK + K T T S
Sbjct: 120 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPKKKKHKGGSEFTD--------TILS 170
Query: 157 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216
VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDC IEWFHFACV LTTKP+GKWFCP
Sbjct: 171 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP 230
Query: 217 RCSQERKKK 225
RC QE++KK
Sbjct: 231 RCVQEKRKK 239
>gi|189083832 inhibitor of growth family, member 4 isoform 6 [Homo
sapiens]
Length = 179
Score = 265 bits (677), Expect = 2e-71
Identities = 144/172 (83%), Positives = 145/172 (84%), Gaps = 24/172 (13%)
Query: 1 MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36
MAAGMYLEHYLD+ LKAEIDKLATEYMSSARSLSSEE
Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
Query: 37 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96
KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
Query: 97 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 148
YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P G
Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172
>gi|38201667 inhibitor of growth family, member 1 isoform A [Homo
sapiens]
Length = 279
Score = 152 bits (384), Expect = 2e-37
Identities = 87/250 (34%), Positives = 130/250 (52%), Gaps = 33/250 (13%)
Query: 6 YLEHYLDNLKA-------------EIDKLATE--------YMSSARSLSSEEKLALLKQI 44
Y+E YLD++++ EID E Y +R +K +L +
Sbjct: 15 YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDECYERFSRETDGAQKRRMLHCV 74
Query: 45 QEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDYDSSSS 102
Q A + +E GD+K+Q+ Q E+V+ R++D+ + FEA +L + S +
Sbjct: 75 QRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRP 134
Query: 103 KGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTF 154
KG+ + K K++ R R+ N D + + K K +TS +
Sbjct: 135 KGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAK- 193
Query: 155 GSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWF 214
+ + D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL KP+GKW+
Sbjct: 194 -AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWY 252
Query: 215 CPRCSQERKK 224
CP+C E +K
Sbjct: 253 CPKCRGENEK 262
>gi|38201663 inhibitor of growth family, member 1 isoform C [Homo
sapiens]
Length = 235
Score = 150 bits (379), Expect = 8e-37
Identities = 78/210 (37%), Positives = 116/210 (55%), Gaps = 12/210 (5%)
Query: 25 YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 84
Y +R +K +L +Q A + +E GD+K+Q+ Q E+V+ R++D+ + FE
Sbjct: 11 YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 70
Query: 85 A--DLKEKQIESSDYDSSSSKGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTA 134
A +L + S + KG+ + K K++ R R+ N D + +
Sbjct: 71 AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASG 130
Query: 135 QKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCS 194
K K +TS + + + D+P+DPNEPTYCLC+QVSYGEMIGCDN +C
Sbjct: 131 TPKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECP 188
Query: 195 IEWFHFACVGLTTKPRGKWFCPRCSQERKK 224
IEWFHF+CVGL KP+GKW+CP+C E +K
Sbjct: 189 IEWFHFSCVGLNHKPKGKWYCPKCRGENEK 218
>gi|38201661 inhibitor of growth family, member 1 isoform D [Homo
sapiens]
Length = 422
Score = 150 bits (379), Expect = 8e-37
Identities = 78/210 (37%), Positives = 116/210 (55%), Gaps = 12/210 (5%)
Query: 25 YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 84
Y +R +K +L +Q A + +E GD+K+Q+ Q E+V+ R++D+ + FE
Sbjct: 198 YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 257
Query: 85 A--DLKEKQIESSDYDSSSSKGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTA 134
A +L + S + KG+ + K K++ R R+ N D + +
Sbjct: 258 AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASG 317
Query: 135 QKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCS 194
K K +TS + + + D+P+DPNEPTYCLC+QVSYGEMIGCDN +C
Sbjct: 318 TPKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECP 375
Query: 195 IEWFHFACVGLTTKPRGKWFCPRCSQERKK 224
IEWFHF+CVGL KP+GKW+CP+C E +K
Sbjct: 376 IEWFHFSCVGLNHKPKGKWYCPKCRGENEK 405
>gi|38201665 inhibitor of growth family, member 1 isoform B [Homo
sapiens]
Length = 210
Score = 146 bits (369), Expect = 1e-35
Identities = 75/195 (38%), Positives = 111/195 (56%), Gaps = 12/195 (6%)
Query: 40 LLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDY 97
+L +Q A + +E GD+K+Q+ Q E+V+ R++D+ + FEA +L + S
Sbjct: 1 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA 60
Query: 98 DSSSSKGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTAQKKLKLVRTSPEYGM 149
+ KG+ + K K++ R R+ N D + + K K +TS +
Sbjct: 61 GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR 120
Query: 150 PSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKP 209
+ + D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL KP
Sbjct: 121 SKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKP 178
Query: 210 RGKWFCPRCSQERKK 224
+GKW+CP+C E +K
Sbjct: 179 KGKWYCPKCRGENEK 193
>gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]
Length = 280
Score = 140 bits (352), Expect = 1e-33
Identities = 80/224 (35%), Positives = 120/224 (53%), Gaps = 24/224 (10%)
Query: 10 YLDNLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMV 69
Y + LK EID + +Y +K L + +Q A +E GD+K+Q+ Q E+V
Sbjct: 56 YQETLK-EIDDVYEKYKKED---DLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELV 111
Query: 70 DKHIRRLDTDLARFEADLK-EKQIESSDYDSS----SSKGKKKGRTQKEKKAARARSKGK 124
+ R+++ F+ + E+ + + DSS SS+ ++ RT + + + +
Sbjct: 112 ENRARQMELHSQCFQDPAESERASDKAKMDSSQPERSSRRPRRQRTSESRDLCHMANGIE 171
Query: 125 NSDEEAPKTAQ----KKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQV 180
+ D++ PK + KK K + E V F +DPNEPTYCLC+QV
Sbjct: 172 DCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFA-----------IDPNEPTYCLCNQV 220
Query: 181 SYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKK 224
SYGEMIGCDN C IEWFHF+CV LT KP+GKW+CP+C + +K
Sbjct: 221 SYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEK 264
>gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo
sapiens]
Length = 418
Score = 115 bits (289), Expect = 2e-26
Identities = 49/127 (38%), Positives = 72/127 (56%), Gaps = 3/127 (2%)
Query: 99 SSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVH 158
SSS+ + GR K + ++ +S + + +V+ E +
Sbjct: 290 SSSAADSRSGRKSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQ---EISQQTTVVPESD 346
Query: 159 PSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC 218
+ +D DPNEP YC+C+QVSYGEM+GCDN DC IEWFH+ CVGLT P+GKW+CP+C
Sbjct: 347 SNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC 406
Query: 219 SQERKKK 225
+ K++
Sbjct: 407 TAAMKRR 413
Score = 57.4 bits (137), Expect = 1e-08
Identities = 26/78 (33%), Positives = 50/78 (64%)
Query: 11 LDNLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVD 70
+ N ++++ +E+ +A+ E + + I++ Y K E D+KVQLA Q Y++VD
Sbjct: 32 VQNAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLVD 91
Query: 71 KHIRRLDTDLARFEADLK 88
+H+R+LD +LA+F+ +L+
Sbjct: 92 RHLRKLDQELAKFKMELE 109
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 49.7 bits (117), Expect = 2e-06
Identities = 20/43 (46%), Positives = 30/43 (69%), Gaps = 5/43 (11%)
Query: 185 MIGCDNPDCSIEWFHFACVGLTTKP--RGKWFCPRCSQERKKK 225
MIGCD+ D +W+H+ CVG+ T P +WFCP+C+ ++K K
Sbjct: 880 MIGCDDCD---DWYHWPCVGIMTAPPEEMQWFCPKCANKKKDK 919
Score = 30.8 bits (68), Expect = 0.98
Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 83 FEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKL-- 140
FE K K+ E K K+K + +KEK+ + + + + ++E K +K+K+
Sbjct: 690 FEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEP 749
Query: 141 VRTSPEYGMPSVT 153
V +P +P +T
Sbjct: 750 VALAPSPVIPRLT 762
>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
sapiens]
Length = 1188
Score = 48.1 bits (113), Expect = 6e-06
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 24/156 (15%)
Query: 80 LARFEADLKEKQIESSDYDS-SSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKL 138
LA E +++ +E D + S G + QK K + S +S ++ + KK
Sbjct: 6 LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65
Query: 139 KL-------------VRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGE 184
K +R P Y M + P DV+ P D YC +CH+ G+
Sbjct: 66 KKPGLLNSNNKEQSELRHGPFYYMKQPL--TTDPVDVV--PQDGRNDFYCWVCHRE--GQ 119
Query: 185 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQ 220
++ C+ +H C+ LT++P G WFCP C +
Sbjct: 120 VLCCE---LCPRVYHAKCLRLTSEPEGDWFCPECEK 152
>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
sapiens]
Length = 1160
Score = 48.1 bits (113), Expect = 6e-06
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 24/156 (15%)
Query: 80 LARFEADLKEKQIESSDYDS-SSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKL 138
LA E +++ +E D + S G + QK K + S +S ++ + KK
Sbjct: 6 LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65
Query: 139 KL-------------VRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGE 184
K +R P Y M + P DV+ P D YC +CH+ G+
Sbjct: 66 KKPGLLNSNNKEQSELRHGPFYYMKQPL--TTDPVDVV--PQDGRNDFYCWVCHRE--GQ 119
Query: 185 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQ 220
++ C+ +H C+ LT++P G WFCP C +
Sbjct: 120 VLCCE---LCPRVYHAKCLRLTSEPEGDWFCPECEK 152
>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
Length = 660
Score = 44.7 bits (104), Expect = 7e-05
Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 7/59 (11%)
Query: 170 NEPTYCLCHQVSYG-EMIGCDNPDCSIEWFHFACVGLT---TKPRGKWFCPRCSQERKK 224
N P YC+C + MIGCDN C+ EWFH C+ +T K +W+C C ++ K
Sbjct: 24 NAPIYCICRKPDINCFMIGCDN--CN-EWFHGDCIRITEKMAKAIREWYCRECREKDPK 79
>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
Length = 656
Score = 44.7 bits (104), Expect = 7e-05
Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 7/59 (11%)
Query: 170 NEPTYCLCHQVSYG-EMIGCDNPDCSIEWFHFACVGLT---TKPRGKWFCPRCSQERKK 224
N P YC+C + MIGCDN C+ EWFH C+ +T K +W+C C ++ K
Sbjct: 24 NAPIYCICRKPDINCFMIGCDN--CN-EWFHGDCIRITEKMAKAIREWYCRECREKDPK 79
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 42.0 bits (97), Expect = 4e-04
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 9/133 (6%)
Query: 89 EKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 148
++++E S + KK RT K+KK + K N+ + ++ +LVR++ +
Sbjct: 1411 KRRLEREGLSSERWERVKKMRTPKKKKIKLSHPKDMNNFK---LERERSYELVRSAETHS 1467
Query: 149 MPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTK 208
+PS T S + + P CL + + + CD C+ +WFH CVG++ +
Sbjct: 1468 LPSDTSYSEQEDSEDEDAICP--AVSCLQPEGDEVDWVQCDG-SCN-QWFHQVCVGVSPE 1523
Query: 209 PRGK--WFCPRCS 219
K + C RC+
Sbjct: 1524 MAEKEDYICVRCT 1536
>gi|35493853 otoferlin isoform c [Homo sapiens]
Length = 1307
Score = 41.2 bits (95), Expect = 7e-04
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Query: 86 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTS 144
DL+EK+ +++++ S KGK+K R KE+K + +S G EAP+ + K+ ++
Sbjct: 662 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 721
Query: 145 PE 146
P+
Sbjct: 722 PK 723
>gi|35493868 otoferlin isoform b [Homo sapiens]
Length = 1230
Score = 41.2 bits (95), Expect = 7e-04
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Query: 86 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTS 144
DL+EK+ +++++ S KGK+K R KE+K + +S G EAP+ + K+ ++
Sbjct: 585 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 644
Query: 145 PE 146
P+
Sbjct: 645 PK 646
>gi|35493860 otoferlin isoform d [Homo sapiens]
Length = 1230
Score = 41.2 bits (95), Expect = 7e-04
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Query: 86 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTS 144
DL+EK+ +++++ S KGK+K R KE+K + +S G EAP+ + K+ ++
Sbjct: 585 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 644
Query: 145 PE 146
P+
Sbjct: 645 PK 646
>gi|34740331 otoferlin isoform a [Homo sapiens]
Length = 1997
Score = 41.2 bits (95), Expect = 7e-04
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Query: 86 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTS 144
DL+EK+ +++++ S KGK+K R KE+K + +S G EAP+ + K+ ++
Sbjct: 1352 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 1411
Query: 145 PE 146
P+
Sbjct: 1412 PK 1413
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 40.8 bits (94), Expect = 0.001
Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 183 GEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216
GE++ CD DC + +H C+ LT P GKW CP
Sbjct: 1331 GELVMCDKKDCP-KAYHLLCLNLTQPPYGKWECP 1363
Score = 32.3 bits (72), Expect = 0.34
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 173 TYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC 218
T C + S +I C+ C + FH C+GL + P K+ C C
Sbjct: 702 TVCQICESSGDSLIPCEGECC--KHFHLECLGLASLPDSKFICMEC 745
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 23/143 (16%)
Query: 80 LARFEADLKEKQIESSDYDS-SSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKL 138
LA E +++ +E D + S G + QK K + S +S ++ + KK
Sbjct: 6 LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65
Query: 139 KLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGEMIGCDNPDCSIEW 197
K P + + + D YC +CH+ G+++ C+
Sbjct: 66 K---------KPGLLNSN-------NKEQDGRNDFYCWVCHRE--GQVLCCE---LCPRV 104
Query: 198 FHFACVGLTTKPRGKWFCPRCSQ 220
+H C+ LT++P G WFCP C +
Sbjct: 105 YHAKCLRLTSEPEGDWFCPECEK 127
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 40.4 bits (93), Expect = 0.001
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 12/142 (8%)
Query: 7 LEHYLDNLKAEIDKLATEYMSSARSLSSEEKL--ALLKQIQEAYGKCKEFGDDKVQLAMQ 64
LE K EID L++ S ++S ++ EK+ L Q+ EA GK +E +L Q
Sbjct: 1218 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 1277
Query: 65 TYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGK 124
RL T+ L+EK ES S SK +T++ K+ +K K
Sbjct: 1278 K--------SRLQTEAGELSRQLEEK--ESIVSQLSRSKQAFTQQTEELKRQLEEENKAK 1327
Query: 125 NSDEEAPKTAQKKLKLVRTSPE 146
N+ A ++++ L+R E
Sbjct: 1328 NALAHALQSSRHDCDLLREQYE 1349
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 39.7 bits (91), Expect = 0.002
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 185 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC-SQER 222
++ CD CS+ H AC G+ P G WFC +C SQER
Sbjct: 39 LVYCDGHGCSVA-VHQACYGIVQVPTGPWFCRKCESQER 76
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 39.7 bits (91), Expect = 0.002
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 185 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC-SQER 222
++ CD CS+ H AC G+ P G WFC +C SQER
Sbjct: 39 LVYCDGHGCSVA-VHQACYGIVQVPTGPWFCRKCESQER 76
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 39.3 bits (90), Expect = 0.003
Identities = 40/143 (27%), Positives = 60/143 (41%), Gaps = 28/143 (19%)
Query: 94 SSDYDSSSSKGKKKGRTQKEKKAARARS-----KGKNSDEEAP---------KTAQKKLK 139
S D+ ++K K R +K ++ A A+ K +S +E P +TA +
Sbjct: 1185 SKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKE 1244
Query: 140 LVRTSPEY--GMPSVTF--GSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSI 195
V E+ GMP+ G L V N C ++ GE++ C+ C
Sbjct: 1245 TVEEGVEHDPGMPASKKMQGERGGGAALKENVCQN------CEKL--GELLLCEAQCCGA 1296
Query: 196 EWFHFACVGLTTKPRGKWFCPRC 218
FH C+GLT PRGK+ C C
Sbjct: 1297 --FHLECLGLTEMPRGKFICNEC 1317
Score = 38.9 bits (89), Expect = 0.004
Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 183 GEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216
G+++ C P C + +H C+ LT +P GKW CP
Sbjct: 1859 GQLVSCKKPGCP-KVYHADCLNLTKRPAGKWECP 1891
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 39.3 bits (90), Expect = 0.003
Identities = 40/143 (27%), Positives = 60/143 (41%), Gaps = 28/143 (19%)
Query: 94 SSDYDSSSSKGKKKGRTQKEKKAARARS-----KGKNSDEEAP---------KTAQKKLK 139
S D+ ++K K R +K ++ A A+ K +S +E P +TA +
Sbjct: 1454 SKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKE 1513
Query: 140 LVRTSPEY--GMPSVTF--GSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSI 195
V E+ GMP+ G L V N C ++ GE++ C+ C
Sbjct: 1514 TVEEGVEHDPGMPASKKMQGERGGGAALKENVCQN------CEKL--GELLLCEAQCCGA 1565
Query: 196 EWFHFACVGLTTKPRGKWFCPRC 218
FH C+GLT PRGK+ C C
Sbjct: 1566 --FHLECLGLTEMPRGKFICNEC 1586
Score = 38.9 bits (89), Expect = 0.004
Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 183 GEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216
G+++ C P C + +H C+ LT +P GKW CP
Sbjct: 2128 GQLVSCKKPGCP-KVYHADCLNLTKRPAGKWECP 2160
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,569,565
Number of Sequences: 37866
Number of extensions: 389679
Number of successful extensions: 3146
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 122
Number of HSP's successfully gapped in prelim test: 213
Number of HSP's that attempted gapping in prelim test: 2361
Number of HSP's gapped (non-prelim): 833
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.