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Search of human proteins with 187608784
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187608784 transmembrane channel-like 6 [Homo sapiens]
(805 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187608784 transmembrane channel-like 6 [Homo sapiens] 1617 0.0
gi|187608791 transmembrane channel-like 6 [Homo sapiens] 1617 0.0
gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] 403 e-112
gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] 402 e-112
gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] 338 9e-93
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] 199 7e-51
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] 194 4e-49
gi|23943900 transmembrane channel-like 8 [Homo sapiens] 171 2e-42
gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] 149 8e-36
gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] 149 1e-35
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 134 3e-31
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap... 125 2e-28
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 97 6e-20
gi|225637475 solute carrier organic anion transporter family, me... 33 1.1
gi|225637473 solute carrier organic anion transporter family, me... 33 1.1
gi|24475871 G protein-coupled receptor 114 [Homo sapiens] 32 2.3
gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens] 32 3.1
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens] 32 3.1
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens] 32 3.1
gi|22325364 ubiquitin associated protein 2 [Homo sapiens] 32 3.1
gi|147905620 PR domain containing 9 [Homo sapiens] 31 5.2
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 31 5.2
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H... 31 5.2
gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3 [... 30 6.8
gi|224809414 Homer, neuronal immediate early gene, 3 isoform 1 [... 30 6.8
gi|224809408 Homer, neuronal immediate early gene, 3 isoform 1 [... 30 6.8
gi|222831612 solute carrier family 44, member 2 isoform 1 [Homo ... 30 8.9
gi|222831610 solute carrier family 44, member 2 isoform 2 [Homo ... 30 8.9
gi|21918872 lactation elevated 1 [Homo sapiens] 30 8.9
>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 1617 bits (4187), Expect = 0.0
Identities = 805/805 (100%), Positives = 805/805 (100%)
Query: 1 MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVT 60
MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVT
Sbjct: 1 MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVT 60
Query: 61 GSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNF 120
GSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNF
Sbjct: 61 GSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNF 120
Query: 121 VRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLRE 180
VRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLRE
Sbjct: 121 VRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLRE 180
Query: 181 KSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQ 240
KSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQ
Sbjct: 181 KSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQ 240
Query: 241 FGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCF 300
FGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCF
Sbjct: 241 FGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCF 300
Query: 301 THTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVY 360
THTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVY
Sbjct: 301 THTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVY 360
Query: 361 SMAHSFGESYRVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHS 420
SMAHSFGESYRVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHS
Sbjct: 361 SMAHSFGESYRVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHS 420
Query: 421 PRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVG 480
PRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVG
Sbjct: 421 PRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVG 480
Query: 481 LLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQC 540
LLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQC
Sbjct: 481 LLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQC 540
Query: 541 WEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQ 600
WEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQ
Sbjct: 541 WEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQ 600
Query: 601 TLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPA 660
TLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPA
Sbjct: 601 TLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPA 660
Query: 661 FLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLME 720
FLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLME
Sbjct: 661 FLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLME 720
Query: 721 NTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKER 780
NTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKER
Sbjct: 721 NTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKER 780
Query: 781 EERSRVGTTEEAAAPPALLTDEQDA 805
EERSRVGTTEEAAAPPALLTDEQDA
Sbjct: 781 EERSRVGTTEEAAAPPALLTDEQDA 805
>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 1617 bits (4187), Expect = 0.0
Identities = 805/805 (100%), Positives = 805/805 (100%)
Query: 1 MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVT 60
MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVT
Sbjct: 1 MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVT 60
Query: 61 GSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNF 120
GSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNF
Sbjct: 61 GSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNF 120
Query: 121 VRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLRE 180
VRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLRE
Sbjct: 121 VRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLRE 180
Query: 181 KSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQ 240
KSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQ
Sbjct: 181 KSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQ 240
Query: 241 FGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCF 300
FGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCF
Sbjct: 241 FGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCF 300
Query: 301 THTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVY 360
THTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVY
Sbjct: 301 THTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVY 360
Query: 361 SMAHSFGESYRVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHS 420
SMAHSFGESYRVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHS
Sbjct: 361 SMAHSFGESYRVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHS 420
Query: 421 PRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVG 480
PRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVG
Sbjct: 421 PRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVG 480
Query: 481 LLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQC 540
LLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQC
Sbjct: 481 LLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQC 540
Query: 541 WEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQ 600
WEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQ
Sbjct: 541 WEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQ 600
Query: 601 TLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPA 660
TLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPA
Sbjct: 601 TLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPA 660
Query: 661 FLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLME 720
FLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLME
Sbjct: 661 FLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLME 720
Query: 721 NTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKER 780
NTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKER
Sbjct: 721 NTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKER 780
Query: 781 EERSRVGTTEEAAAPPALLTDEQDA 805
EERSRVGTTEEAAAPPALLTDEQDA
Sbjct: 781 EERSRVGTTEEAAAPPALLTDEQDA 805
>gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]
Length = 760
Score = 403 bits (1036), Expect = e-112
Identities = 235/649 (36%), Positives = 359/649 (55%), Gaps = 23/649 (3%)
Query: 137 PTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSG 196
P + E + L+ L + R +R P ++ EKR+LR+ + K Q
Sbjct: 95 PGSSHETVQGQKLIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSK---QTHRI 151
Query: 197 GVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLL 256
+CC + + A +L L ++ W+ LK IGG+FG+SVLSYF FL+ LL
Sbjct: 152 LQLNCCIQCLNSISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLL 211
Query: 257 AFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCFTHTVMYYGHYSNATLN 316
FN +L +FI+ PQ F A TGLE TG G F TVMYYG Y+N+T+
Sbjct: 212 KFNIFSFILNFSFIIIPQ--FTVAKKNTLQF-TGLEFFTGVGYFRDTVMYYGFYTNSTIQ 268
Query: 317 QPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESY-RVGST 375
G+ G YNM LAY+ T+G +L++SMA F ++
Sbjct: 269 H-------GNS------GASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIY 315
Query: 376 SGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLG 435
SG +FC WD+ VT ++A +L+Q N+ T ++E L+E + +S + L + +
Sbjct: 316 SGGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYM 374
Query: 436 LVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAA 495
+ W++ G A+ C AV+ +E+ ++ + +L+LP VV +NL P + +
Sbjct: 375 VAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLLLPFVVSCINLAVPCIYSMFRL 434
Query: 496 LEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVM 555
+E ++ P EVYV + RN+ LK++I+G LCY+WL V + +CWE +GQ++YR L+M
Sbjct: 435 VERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNT-VALSGEECWETLIGQDIYRLLLM 493
Query: 556 DFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPA 615
DFV L+++ GE + RII + + EFDIARNVLELIY QTL W+G+ F PLLP
Sbjct: 494 DFVFSLVNSFLGEFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPF 553
Query: 616 VQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQV 675
+Q+I L ++FY K SL+ N Q P + W AS M T F+ LL FP+F G L +W++
Sbjct: 554 IQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRL 613
Query: 676 KPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAV 735
KPS+ CGPFR L + W+ L + P W+ W++R L+ + F F+++ ++L +
Sbjct: 614 KPSADCGPFRGLPLFIHSIYSWIDTL-STRPGYLWVVWIYRNLIGSVHFFFILTLIVLII 672
Query: 736 IYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKEREERS 784
YL Q+ G++ +I LL EQI NEG+DK+FLI KL + + +++ S
Sbjct: 673 TYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQDMEKKANPS 721
>gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]
Length = 1006
Score = 402 bits (1033), Expect = e-112
Identities = 233/637 (36%), Positives = 355/637 (55%), Gaps = 23/637 (3%)
Query: 149 LVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSGGVCSCCGRLRYA 208
L+ L + R +R P ++ EKR+LR+ + K Q +CC + +
Sbjct: 353 LIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSK---QTHRILQLNCCIQCLNS 409
Query: 209 CVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVA 268
A +L L ++ W+ LK IGG+FG+SVLSYF FL+ LL FN +L +
Sbjct: 410 ISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFS 469
Query: 269 FIMGPQVAFPPALPGPAPVCTGLELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQC 328
FI+ PQ F A TGLE TG G F TVMYYG Y+N+T+ G+
Sbjct: 470 FIIIPQ--FTVAKKNTLQF-TGLEFFTGVGYFRDTVMYYGFYTNSTIQH-------GNS- 518
Query: 329 TPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESY-RVGSTSGIHAITVFCSW 387
G YNM LAY+ T+G +L++SMA F ++ SG +FC W
Sbjct: 519 -----GASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572
Query: 388 DYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALG 447
D+ VT ++A +L+Q N+ T ++E L+E + +S + L + + + W++ G A+
Sbjct: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIA 632
Query: 448 CAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVY 507
C AV+ +E+ ++ + +L+LP VV +NL P + + +E ++ P EVY
Sbjct: 633 CCAAVYYLAEYNLEFLKTHSNPGAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVY 692
Query: 508 VAICRNLILKLAILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFG 567
V + RN+ LK++I+G LCY+WL V + +CWE +GQ++YR L+MDFV L+++ G
Sbjct: 693 VLLIRNIFLKISIIGILCYYWLNT-VALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLG 751
Query: 568 ELVWRIISEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYV 627
E + RII + + EFDIARNVLELIY QTL W+G+ F PLLP +Q+I L ++FY
Sbjct: 752 EFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYS 811
Query: 628 KKTSLLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTL 687
K SL+ N Q P + W AS M T F+ LL FP+F G L +W++KPS+ CGPFR L
Sbjct: 812 KNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGL 871
Query: 688 DTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQR 747
+ W+ L + P W+ W++R L+ + F F+++ ++L + YL Q+ G++
Sbjct: 872 PLFIHSIYSWIDTL-STRPGYLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRK 930
Query: 748 KVICLLKEQISNEGEDKIFLINKLHSIYERKEREERS 784
+I LL EQI NEG+DK+FLI KL + + +++ S
Sbjct: 931 IMIRLLHEQIINEGKDKMFLIEKLIKLQDMEKKANPS 967
>gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]
Length = 948
Score = 338 bits (868), Expect = 9e-93
Identities = 214/637 (33%), Positives = 324/637 (50%), Gaps = 81/637 (12%)
Query: 149 LVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSGGVCSCCGRLRYA 208
L+ L + R +R P ++ EKR+LR+ + K Q +CC + +
Sbjct: 353 LIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSK---QTHRILQLNCCIQCLNS 409
Query: 209 CVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVA 268
A +L L ++ W+ LK IGG+FG+SVLSYF FL+ LL FN +L +
Sbjct: 410 ISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFS 469
Query: 269 FIMGPQVAFPPALPGPAPVCTGLELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQC 328
FI+ PQ F A TGLE TG G F TVMYYG Y+N+T+ G+
Sbjct: 470 FIIIPQ--FTVAKKNTLQF-TGLEFFTGVGYFRDTVMYYGFYTNSTIQH-------GNS- 518
Query: 329 TPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESY-RVGSTSGIHAITVFCSW 387
G YNM LAY+ T+G +L++SMA F ++ SG +FC W
Sbjct: 519 -----GASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572
Query: 388 DYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALG 447
D+ VT ++A +L+Q N+ T ++E L+E + +S + L + + + W++ G A+
Sbjct: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIA 632
Query: 448 CAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVY 507
C AV+ +E+ ++ + +L+LP VV +NL P + + +E ++ P EVY
Sbjct: 633 CCAAVYYLAEYNLEFLKTHSNPGAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVY 692
Query: 508 VAICRNLILKLAILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFG 567
V + RN+ LK++I+G LCY+WL V + +CWE +GQ++YR L+MDFV L+++ G
Sbjct: 693 VLLIRNIFLKISIIGILCYYWLNT-VALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLG 751
Query: 568 ELVWRIISEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYV 627
E + RII + + EFDIARNVLELIY QTL W+G+ F PLLP +Q+I L ++FY
Sbjct: 752 EFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYS 811
Query: 628 KKTSLLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTL 687
K SL+ N Q P + W AS M T F+ LL FP+F G L +W++
Sbjct: 812 KNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRI------------ 859
Query: 688 DTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQR 747
+++L W Q+ G++
Sbjct: 860 --------------------ITYLYW---------------------------QITEGRK 872
Query: 748 KVICLLKEQISNEGEDKIFLINKLHSIYERKEREERS 784
+I LL EQI NEG+DK+FLI KL + + +++ S
Sbjct: 873 IMIRLLHEQIINEGKDKMFLIEKLIKLQDMEKKANPS 909
>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
Length = 723
Score = 199 bits (507), Expect = 7e-51
Identities = 189/740 (25%), Positives = 326/740 (44%), Gaps = 120/740 (16%)
Query: 103 NRTVQLRCRSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEEKQS-LLVKELQSLAVAQR 161
N ++ C SS P+ NF++ PS R + T + +KQS L+K S +
Sbjct: 24 NLSLDSSCFSSPPV--NFLQEL-PSYR--SIARRRTTVHSRDKQSGTLLKPTDSYSSQLE 78
Query: 162 D--------HMLRGMPLSLAEKRSLREKSRTPR------GKWRGQPGSGGVCSCCGRLRY 207
D H LR L+++EKR LR+ T +W+ S L
Sbjct: 79 DRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQWKRYSSK----SWKRFLEK 134
Query: 208 ACVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLV 267
A + H L WR ++ I G+FG+ + SYF FL+ L+ N ++ L++
Sbjct: 135 AREMTTH------------LELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIF 182
Query: 268 AFIMGPQVAFPPALPGPAPV----------CTG---------------LELLTGAGCFTH 302
++ P + + + V CT ++LL+G G
Sbjct: 183 MLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEE 242
Query: 303 TVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSM 362
T ++YGHY+ +DG + Y++PLAYL + S ++ + +V
Sbjct: 243 TSLFYGHYT-----------IDGV----KFQNFTYDLPLAYLLSTIASLALSLLWIVKRS 287
Query: 363 AHSFGESY-RVGSTSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSP 421
F + R + +F WD+ +T + + L+ ++R L+ L E ++R
Sbjct: 288 VEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMR--- 344
Query: 422 RSVCGRLRQAAV--------LGLVWLLCLGTALGCAVAVHVFSEFMIQSP---EAAGQEA 470
+ + R + + L + L LG VFS+ ++ G+
Sbjct: 345 QKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENL 404
Query: 471 VLLVLP-LVVGLLNLGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWL 529
+L LP +V+ L N P + + E + SP E+ + I R + ++LA + L + L
Sbjct: 405 FILYLPSIVITLANFITPMIFAKIIRYEDY-SPGFEIRLTILRCVFMRLATICVLVFT-L 462
Query: 530 GRRVGVLQGQ-------------CWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRII-- 574
G ++ CWE VGQE+Y+ ++ DF+++L TLF + +++
Sbjct: 463 GSKITSCDDDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVT 522
Query: 575 ---SEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTS 631
S K ++ + EF I NVL ++YGQT+ W+G FSPLLPA+ +K +++FYVK+ S
Sbjct: 523 YCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWS 582
Query: 632 LLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMY 691
LL C+ RP+ AS+ + FL +L L A + L ++ ++ S CGPF +T +
Sbjct: 583 LLYTCRPSPRPFRASNSNFFFLLVLLIGLCL-AIIPLTISISRIPSSKACGPFTNFNTTW 641
Query: 692 EAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVIC 751
E V + S ++H E F + ++ +++ I + ++V+
Sbjct: 642 EVIPKTVSTFPS-----SLQSFIHGVTSEAFAVPFFM--IICLIMFYFIALAGAHKRVVI 694
Query: 752 LLKEQISNEGEDKIFLINKL 771
L+EQ+S E DK +LI KL
Sbjct: 695 QLREQLSLESRDKCYLIQKL 714
>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
Length = 613
Score = 194 bits (492), Expect = 4e-49
Identities = 155/598 (25%), Positives = 275/598 (45%), Gaps = 84/598 (14%)
Query: 230 WRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPV-- 287
WR ++ I G+FG+ + SYF FL+ L+ N ++ L++ ++ P + + + V
Sbjct: 35 WREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLI 94
Query: 288 --------CTG---------------LELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLD 324
CT ++LL+G G T ++YGHY+ +D
Sbjct: 95 PFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYT-----------ID 143
Query: 325 GSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESY-RVGSTSGIHAITV 383
G + Y++PLAYL + S ++ + +V F + R + +
Sbjct: 144 GV----KFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKI 199
Query: 384 FCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAV--------LG 435
F WD+ +T + + L+ ++R L+ L E ++R + + R + + L
Sbjct: 200 FAGWDFCITNRSMADLKHSSLRYELRADLEEERMR---QKIAERTSEETIRIYSLRLFLN 256
Query: 436 LVWLLCLGTALGCAVAVHVFSEFMIQSP---EAAGQEAVLLVLP-LVVGLLNLGAPYLCR 491
+ L LG VFS+ ++ G+ +L LP +V+ L N P +
Sbjct: 257 CIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFA 316
Query: 492 VLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQ------------ 539
+ E + SP E+ + I R + ++LA + L + LG ++
Sbjct: 317 KIIRYEDY-SPGFEIRLTILRCVFMRLATICVLVFT-LGSKITSCDDDTCDLCGYNQKLY 374
Query: 540 -CWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRII-----SEKKLKRRRKPEFDIARNV 593
CWE VGQE+Y+ ++ DF+++L TLF + +++ S K ++ + EF I NV
Sbjct: 375 PCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNV 434
Query: 594 LELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFL 653
L ++YGQT+ W+G FSPLLPA+ +K +++FYVK+ SLL C+ RP+ AS+ + FL
Sbjct: 435 LGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFL 494
Query: 654 TLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPW 713
+L L A + L ++ ++ S CGPF +T +E V + S +
Sbjct: 495 LVLLIGLCL-AIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPS-----SLQSF 548
Query: 714 VHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKL 771
+H E F + ++ +++ I + ++V+ L+EQ+S E DK +LI KL
Sbjct: 549 IHGVTSEAFAVPFFM--IICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKL 604
>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
Length = 726
Score = 171 bits (434), Expect = 2e-42
Identities = 190/670 (28%), Positives = 293/670 (43%), Gaps = 122/670 (18%)
Query: 165 LRGMPLSLAEKR---SLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALL 221
+RG+P ++ +KR LRE + +W+ RLR A LGL
Sbjct: 36 VRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVE--RRLREAAQRLARGLGL--- 90
Query: 222 SALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPAL 281
W AL IGG FG+ + SYF FL+ LL N L LLL +F++ P V P
Sbjct: 91 --------WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPD 142
Query: 282 PGPAP----VCTGLE---------------LLTGAGCFTHTVMYYGHYSNATLNQPCGSP 322
PGP C G +LTG FT+T ++YG Y
Sbjct: 143 PGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRA-FTNTYLFYGAY------------ 189
Query: 323 LDGSQCTPRVG---GLPYNMPLAYL-STVGVSFFITCITL---VYSMAHS--FGESYRVG 373
RVG Y++ LAYL S + C TL V + G+ Y+
Sbjct: 190 --------RVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAP 241
Query: 374 STSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAE------WQLRHSPRSVCGR 427
++ VF SWD+ + + A+ +++ I K L E Q + ++ C
Sbjct: 242 LSA-----KVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRL 296
Query: 428 LRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVL----PLVVGLLN 483
L V L LL +G A++ ++ Q + +E++ L+L P V+ L+N
Sbjct: 297 LSYLRVNVLNGLLVVG-----AISAIFWATKYSQDNK---EESLFLLLQYLPPGVIALVN 348
Query: 484 LGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRV---------- 533
P L L LE + P EV + + ++LKLA LG LG+ +
Sbjct: 349 FLGPLLFTFLVQLENYP-PNTEVNLTLIWCVVLKLASLGMFSVS-LGQTILCIGRDKSSC 406
Query: 534 -----GVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKR----RRK 584
V QCWE+ VG+ELY+ + +F+L + L R++ ++ R +
Sbjct: 407 ESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLER 466
Query: 585 PEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWL 644
EF + +NVL+++ GQT+TW+G+ + PLLP + + L L FY+KK +LL N +A RP+
Sbjct: 467 EEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFR 526
Query: 645 ASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAA 704
AS ST F L+ L AAV L Y V + S CG F T Y A V L A
Sbjct: 527 AS-SSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLF----TNYSAPWQVVPELVAL 581
Query: 705 GPRVSWLPWVHR---YLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEG 761
G LP + + + + + F F + +L V+ + + + + I L++Q+ +
Sbjct: 582 G-----LPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQV 636
Query: 762 EDKIFLINKL 771
++K L+ L
Sbjct: 637 QEKWHLVEDL 646
>gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]
Length = 712
Score = 149 bits (377), Expect = 8e-36
Identities = 197/745 (26%), Positives = 309/745 (41%), Gaps = 140/745 (18%)
Query: 110 CRSSRPLLGNFVRS--AWPSLRLYDLELDPT-ALEEEEKQSLLVKELQSLAVA---QRDH 163
C S P L + + + +LR D + P ALEEEE+ ++ + Q H
Sbjct: 29 CSSPGPSLSSVLNELPSAATLRYRDPGVLPWGALEEEEEDGGRSRKAFTEVTQTELQDPH 88
Query: 164 MLRGMPLSLAEKRSLREKSRTPRGKWRGQP--GSGGVCSCCGRLRYACVLALHSLGLALL 221
R +P + +R+ R+++ + R Q GSG RL L
Sbjct: 89 PSRELPWPMQARRAHRQRNAS-----RDQVVYGSGTKTDRWARL-------LRRSKEKTK 136
Query: 222 SALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQV--AFPP 279
L++L PW + LKRIGGQFG+ SYF L+ LL N L +L+ + P PP
Sbjct: 137 EGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPP 196
Query: 280 ALPGPA---------PVCTGL--------ELLTGAGCFTHTVMYYGHYSNATLNQPCGSP 322
PGP P GL LL+G G + ++YG Y
Sbjct: 197 GPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPR--------- 247
Query: 323 LDGSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAIT 382
PR+ + Y L + VG + C+ L+ + S + + + + + +
Sbjct: 248 -------PRLA-VTY---LCWAFAVG----LICLLLILHRSVSGLKQTLLAESEALTSYS 292
Query: 383 --VFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGL---- 436
VF +WD+ + RL+Q I LK L E +R RQAAV L
Sbjct: 293 HRVFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVR----------RQAAVRTLGQQA 342
Query: 437 -VWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLV--VGLLNLGAPYL---- 489
VWL+ + L + V + A G L +PLV + LL LG YL
Sbjct: 343 RVWLVRVLLNL---LVVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIF 399
Query: 490 -----------CRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYH-WLGRRVG--- 534
+++A LE + V++ + R + L+LA L L + W G
Sbjct: 400 IAGVNFVLPPVFKLIAPLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDS 458
Query: 535 -----------VLQGQCWEDFVGQELYRFLVMDFVLMLLDTLF----GELVWRIISEKKL 579
Q CWE +GQE+Y+ L+ D + +L L +L+ +
Sbjct: 459 EAEDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALG 518
Query: 580 KRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAP 639
+ EF + VL LIY QT+ W+G F PLLP + +K LL+FY+KK +L + C
Sbjct: 519 RLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPA 578
Query: 640 RRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVR 699
R + AS + F L+ ++V L Y+++ + PS CGPFR + +W +
Sbjct: 579 ARTFRAS-AANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSS------IWAQ 631
Query: 700 HLEAAGPRVSWLPWVHR----YLMENTFFV--FLVSALLLAVIYLNIQVVRGQRKVICLL 753
E+ +S LP + +L F V L+S++L+A + + ++I L
Sbjct: 632 IPES----ISSLPETTQNFLFFLGTQAFAVPLLLISSILMA---YTVALANSYGRLISEL 684
Query: 754 KEQISNEGEDKIFLINKLHSIYERK 778
K Q E ++K+FL + ++ K
Sbjct: 685 KRQRQTEAQNKVFLARRAVALTSTK 709
>gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]
Length = 706
Score = 149 bits (376), Expect = 1e-35
Identities = 169/623 (27%), Positives = 264/623 (42%), Gaps = 120/623 (19%)
Query: 224 LQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQV--AFPPAL 281
L++L PW + LKRIGGQFG+ SYF L+ LL N L +L+ + P PP
Sbjct: 133 LRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGP 192
Query: 282 PGPA---------PVCTGL--------ELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLD 324
PGP P GL LL+G G + ++YG Y
Sbjct: 193 PGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPR----------- 241
Query: 325 GSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAIT-- 382
PR+ + Y L + VG + C+ L+ + S + + + + + +
Sbjct: 242 -----PRLA-VTY---LCWAFAVG----LICLLLILHRSVSGLKQTLLAESEALTSYSHR 288
Query: 383 VFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGL-----V 437
VF +WD+ + RL+Q I LK L E +R RQAAV L V
Sbjct: 289 VFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVR----------RQAAVRTLGQQARV 338
Query: 438 WLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLV--VGLLNLGAPYL------ 489
WL+ + L + V + A G L +PLV + LL LG YL
Sbjct: 339 WLVRVLLNL---LVVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIA 395
Query: 490 ---------CRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYH-WLGRRVG----- 534
+++A LE + V++ + R + L+LA L L + W G
Sbjct: 396 GVNFVLPPVFKLIAPLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDSEA 454
Query: 535 ---------VLQGQCWEDFVGQELYRFLVMDFVLMLLDTLF----GELVWRIISEKKLKR 581
Q CWE +GQE+Y+ L+ D + +L L +L+ + +
Sbjct: 455 EDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRL 514
Query: 582 RRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRR 641
EF + VL LIY QT+ W+G F PLLP + +K LL+FY+KK +L + C R
Sbjct: 515 AGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAAR 574
Query: 642 PWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHL 701
+ AS + F L+ ++V L Y+++ + PS CGPFR + +W +
Sbjct: 575 TFRAS-AANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSS------IWAQIP 627
Query: 702 EAAGPRVSWLPWVHR----YLMENTFFV--FLVSALLLAVIYLNIQVVRGQRKVICLLKE 755
E+ +S LP + +L F V L+S++L+A + + ++I LK
Sbjct: 628 ES----ISSLPETTQNFLFFLGTQAFAVPLLLISSILMA---YTVALANSYGRLISELKR 680
Query: 756 QISNEGEDKIFLINKLHSIYERK 778
Q E ++K+FL + ++ K
Sbjct: 681 QRQTEAQNKVFLARRAVALTSTK 703
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 134 bits (337), Expect = 3e-31
Identities = 146/598 (24%), Positives = 243/598 (40%), Gaps = 95/598 (15%)
Query: 226 ALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFP-PALPGP 284
A +PW +K I QFGSSV SYFLFL+ + N +L +L + IM P+ + P P
Sbjct: 166 ACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLP 225
Query: 285 APVCTGLELLTGA---------GCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGL 335
E + A G ++V++YG+Y N +G +
Sbjct: 226 RKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRT----------------IGWM 269
Query: 336 PYNMPLAY----LSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAITVFCSWDYKV 391
+ +PL+Y + +G SF + ++ +M + G+ + + VF SWDY +
Sbjct: 270 NFRLPLSYFLVGIMCIGYSFLV----VLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLI 325
Query: 392 TQKRASRLQQDNIRTRLKELLAEWQLRHSPRSV-CGRLRQAAVLGLVWLLCLGTALGCAV 450
+ + ++I KE + E + +V R + V+L G+
Sbjct: 326 GNPETADNKFNSITMNFKEAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFW 385
Query: 451 AVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVL------ 504
AV EF Q P+ G + +V+ LL + P L + A LE + +
Sbjct: 386 AVKRSQEFAQQDPDTLGWWEKN-EMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLG 444
Query: 505 EVYVAICRNL-ILKLAILGTLCYH-------------WLGRRV----------------- 533
++ + NL + LA++ + W +
Sbjct: 445 RIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFF 504
Query: 534 ----GVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIIS---------EKKLK 580
V +G CWE VGQE R V D + + L G+ + + +
Sbjct: 505 VHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYG 564
Query: 581 RRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPR 640
EFDI+ NVL LI+ Q + W+G F+P LP + I++L Y + +++ C P
Sbjct: 565 YPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMC-CNVPE 623
Query: 641 -RPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVR 699
R + AS + +L +L FL L Y + + PS CGPF + M+E V
Sbjct: 624 ARVFKASRSNNFYLGMLLLILFLSTMPVL-YMIVSLPPSFDCGPFSGKNRMFE---VIGE 679
Query: 700 HLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQI 757
LE P SW+ + R L + ++ ++LA+ YLN +GQ+ LK+++
Sbjct: 680 TLEHDFP--SWMAKILRQLSNPGLVIAVILVMVLAIYYLN-ATAKGQKAANLDLKKKM 734
>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
sapiens]
Length = 906
Score = 125 bits (314), Expect = 2e-28
Identities = 159/696 (22%), Positives = 273/696 (39%), Gaps = 115/696 (16%)
Query: 111 RSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPL 170
R +P + SA L + EL + EEK+ L+ +R P
Sbjct: 129 RQKKPRSSSLASSASGGESLSEEELAQILEQVEEKKKLIAT-------------MRSKPW 175
Query: 171 SLAEKRSLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQAL--- 227
+A+K + +++ K+ G G G G+ YA + + +
Sbjct: 176 PMAKKLTELREAQEFVEKYEGALGKGK-----GKQLYAYKMLMAKKWVKFKRDFDNFKTQ 230
Query: 228 -MPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFP-PALPGPA 285
+PW +K I FGSSV SYF+FL+ + N +L L+ ++ P+V P P
Sbjct: 231 CIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSIPR 290
Query: 286 PVCTGLE---------LLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLP 336
E L G ++ ++YG+Y+N +G L
Sbjct: 291 KTVPRAEEEKAMDFSVLWDFEGYIKYSALFYGYYNNQRT----------------IGWLR 334
Query: 337 YNMPLAYLSTVGVSFF-ITCITLVYSMAHSFGESYRVGSTSGI-HAITVFCSWDYKVTQK 394
Y +P+AY VGVS F + I ++ SMA + S G + + +F SWDY +
Sbjct: 335 YRLPMAYFM-VGVSVFGYSLIIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLIGNS 393
Query: 395 RASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHV 454
+ + +I T KE + + Q + ++ R VL ++C G + V
Sbjct: 394 ETADNKYASITTSFKESIVDEQESNKEENI-HLTRFLRVLANFLIICCLCGSGYLIYFVV 452
Query: 455 -----FSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHD--------- 500
FS+ S + + +V+ LL + P L +AALE +
Sbjct: 453 KRSQQFSKMQNVSWYERNE------VEIVMSLLGMFCPPLFETIAALENYHPRTGLKWQL 506
Query: 501 --------SPVLEVYVAICRNLILKLAILGTL--CYHWLG------------------RR 532
+ +A+ ++ LKLA T+ HW
Sbjct: 507 GRIFALFLGNLYTFLLALMDDVHLKLANEETIKNITHWTLFNYYNSSGWNESVPRPPLHP 566
Query: 533 VGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIIS---------EKKLKRRR 583
V +G CWE VG E R V D ++ + L G+ + + +
Sbjct: 567 ADVPRGSCWETAVGIEFMRLTVSDMLVTYITILLGDFLRACFVRFMNYCWCWDLEAGFPS 626
Query: 584 KPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPW 643
EFDI+ NVL LI+ Q + W+G ++P L + +++LL Y + +++++ R +
Sbjct: 627 YAEFDISGNVLGLIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVPHERVF 686
Query: 644 LASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEA 703
AS + ++ LL FL + + + Y + + PS CGPF + MY+ V +E
Sbjct: 687 KASRSNNFYMGLLLLVLFL-SLLPVAYTIMSLPPSFDCGPFSGKNRMYD---VLQETIEN 742
Query: 704 AGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLN 739
P ++L + +L + + + LA+ YLN
Sbjct: 743 DFP--TFLGKIFAFLANPGLIIPAILLMFLAIYYLN 776
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 97.1 bits (240), Expect = 6e-20
Identities = 74/239 (30%), Positives = 117/239 (48%), Gaps = 19/239 (7%)
Query: 537 QGQCWEDFVGQELYRFLVMDFVL----MLLDTLFGELVWRIISEK-----KLKRRRKPEF 587
Q QCWE +VGQE+ + ++D + +LL F L R +S+ + K EF
Sbjct: 496 QDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEF 555
Query: 588 DIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAP-RRPWLAS 646
IA NVL L+Y Q + W+G FSP LPA ++KL+ + Y++ ++L C P ++ + AS
Sbjct: 556 KIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVL-TCNVPHQQVFRAS 614
Query: 647 HMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGP 706
+ +L +L F FL + +A+ + KPS CGPF + +Y+ + +E P
Sbjct: 615 RSNNFYLAMLLFMLFL-CMLPTIFAIVRYKPSLNCGPFSGQEKIYD---IVSETIEKDFP 670
Query: 707 RVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISN-EGEDK 764
W V ++ + V L + + YL + R + LK QI N EDK
Sbjct: 671 --VWFGSVVGHISSPVVILPAVLLLFMLIYYLQ-SIARSLKLSNHQLKMQIQNARSEDK 726
Score = 79.3 bits (194), Expect = 1e-14
Identities = 76/311 (24%), Positives = 132/311 (42%), Gaps = 35/311 (11%)
Query: 228 MPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPV 287
+PW +K+I FGS V SYF+FL+ L N +L ++ AFI+ P++ A
Sbjct: 121 IPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARK 180
Query: 288 CTGLELLTGA----------GCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPY 337
E ++ A G ++V++YG+Y ++G Y
Sbjct: 181 TIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRER----------------KIGRAGY 224
Query: 338 NMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSG-IHAITVFCSWDYKVTQKRA 396
+PLAY F + I L+ MA + S S VFC+WDY + A
Sbjct: 225 RLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEA 284
Query: 397 SRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFS 456
+ + I ++E + E Q + +++ + + ++ LL +L ++ + F
Sbjct: 285 AESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANILVLL----SLAGSIYLIYFV 340
Query: 457 EFMIQSPEAAGQEAVLL---VLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVYVAICRN 513
Q E + +E L + +VV L+ + AP ++AALE + P + + R
Sbjct: 341 VDRSQKLEQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMY-HPRTTLRFQLARV 399
Query: 514 LILKLAILGTL 524
L+L L L +L
Sbjct: 400 LVLYLGNLYSL 410
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 33.1 bits (74), Expect = 1.1
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 519 AILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKK 578
A++ T C W + GV QG CWE V + + + L + +F L W I K+
Sbjct: 652 AVIDTTCMLWQ-QECGV-QGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKE 709
Query: 579 --LKRRRKPEFDIA 590
L+RRR+ EF ++
Sbjct: 710 DGLQRRRQREFPLS 723
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 33.1 bits (74), Expect = 1.1
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 519 AILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKK 578
A++ T C W + GV QG CWE V + + + L + +F L W I K+
Sbjct: 707 AVIDTTCMLWQ-QECGV-QGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKE 764
Query: 579 --LKRRRKPEFDIA 590
L+RRR+ EF ++
Sbjct: 765 DGLQRRRQREFPLS 778
>gi|24475871 G protein-coupled receptor 114 [Homo sapiens]
Length = 528
Score = 32.0 bits (71), Expect = 2.3
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 19/120 (15%)
Query: 184 TPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQFGS 243
+P G QP V C L Y VL L AL+ A + L P Y + +G
Sbjct: 205 SPEGCRTEQPSHSQVLCRCNHLTYFAVLM--QLSPALVPA-ELLAPLTY-ISLVGCSISI 260
Query: 244 -----SVLSYFLFLKTL-------LAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGL 291
+VL +F F K + +A +LLL +AF++ P A P P CT L
Sbjct: 261 VASLITVLLHFHFRKQSDSLTRIHMNLHASVLLLNIAFLLSPAFAMSPV---PGSACTAL 317
>gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]
Length = 450
Score = 31.6 bits (70), Expect = 3.1
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 14/88 (15%)
Query: 21 GPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGSSQQTLWRPEGTQSTATLR 80
G SP DE+E +E+ + +E E Q + L +P+G++ ATLR
Sbjct: 290 GASPEDEAE---------EEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLR 340
Query: 81 ILASMPSRTIGRSRGAIISQYYNRTVQL 108
+GR GAI Q++ R QL
Sbjct: 341 -----GQVLLGRGVGAIGGQWWRRRAQL 363
>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
Length = 1302
Score = 31.6 bits (70), Expect = 3.1
Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Query: 3 QPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGS 62
Q + L ET D G+ P+++ + D + + + S+ T ++ +RE+ + G+
Sbjct: 499 QTIVHRLKDEETNEDSGRDLKPHEDQQ--DINKDVGVKTSESTTTVKSKVDEREKYMIGN 556
Query: 63 SQQTLWRPEGTQSTATLRILASM 85
S Q + PE S +L + A+M
Sbjct: 557 SVQKISEPEAEISPGSLPVTANM 579
>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
Length = 1371
Score = 31.6 bits (70), Expect = 3.1
Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Query: 3 QPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGS 62
Q + L ET D G+ P+++ + D + + + S+ T ++ +RE+ + G+
Sbjct: 499 QTIVHRLKDEETNEDSGRDLKPHEDQQ--DINKDVGVKTSESTTTVKSKVDEREKYMIGN 556
Query: 63 SQQTLWRPEGTQSTATLRILASM 85
S Q + PE S +L + A+M
Sbjct: 557 SVQKISEPEAEISPGSLPVTANM 579
>gi|22325364 ubiquitin associated protein 2 [Homo sapiens]
Length = 1119
Score = 31.6 bits (70), Expect = 3.1
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 23 SPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGSSQQTLWRPEGTQSTATLRIL 82
S YD+S VH+ I QS ++ E G SQQTL P+ T + L +
Sbjct: 615 SSYDQSSVHNR----IPYQSPVSSSESAPGTIMNGHGGGRSQQTLDTPKTTGPPSALPSV 670
Query: 83 ASMPSRT 89
+S+PS T
Sbjct: 671 SSLPSTT 677
>gi|147905620 PR domain containing 9 [Homo sapiens]
Length = 894
Score = 30.8 bits (68), Expect = 5.2
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 92 RSRGAIISQYYNRTVQLRCRSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEE--KQSLL 149
++R + + YN + + R++RP R A L++D T +EE + +
Sbjct: 48 KTRYRNVKRNYNALITIGLRATRPAFMCHRRQA------IKLQVDDTEDSDEEWTPRQQV 101
Query: 150 VKELQSLAVAQRDHMLRGMP-LSLAEKRSLREKSRT 184
+L V QR H +GMP S + + SL+E SRT
Sbjct: 102 KPPWMALRVEQRKHQ-KGMPKASFSNESSLKELSRT 136
>gi|219521893 coiled-coil transcriptional coactivator isoform 2
[Homo sapiens]
Length = 606
Score = 30.8 bits (68), Expect = 5.2
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Query: 743 VRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKEREERSRVGTTEEAAAP-----PA 797
+R +V+ KEQ+ E ++ + + KL + E+ E+ + TTE+ A PA
Sbjct: 390 LRSALRVLQKEKEQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTEDEEAAVGLSCPA 449
Query: 798 LLTDEQD 804
LTD +D
Sbjct: 450 ALTDSED 456
>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
sapiens]
Length = 691
Score = 30.8 bits (68), Expect = 5.2
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Query: 743 VRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKEREERSRVGTTEEAAAP-----PA 797
+R +V+ KEQ+ E ++ + + KL + E+ E+ + TTE+ A PA
Sbjct: 475 LRSALRVLQKEKEQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTEDEEAAVGLSCPA 534
Query: 798 LLTDEQD 804
LTD +D
Sbjct: 535 ALTDSED 541
>gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3
[Homo sapiens]
Length = 325
Score = 30.4 bits (67), Expect = 6.8
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Query: 139 ALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGK 188
A E EE Q V++L++ A+ +H LR M SL E R+ RE++R G+
Sbjct: 251 AAEREETQQK-VQDLETRN-AELEHQLRAMERSLEEARAERERARAEVGR 298
>gi|224809414 Homer, neuronal immediate early gene, 3 isoform 1
[Homo sapiens]
Length = 361
Score = 30.4 bits (67), Expect = 6.8
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Query: 139 ALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGK 188
A E EE Q V++L++ A+ +H LR M SL E R+ RE++R G+
Sbjct: 287 AAEREETQQK-VQDLETRN-AELEHQLRAMERSLEEARAERERARAEVGR 334
>gi|224809408 Homer, neuronal immediate early gene, 3 isoform 1
[Homo sapiens]
Length = 361
Score = 30.4 bits (67), Expect = 6.8
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Query: 139 ALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGK 188
A E EE Q V++L++ A+ +H LR M SL E R+ RE++R G+
Sbjct: 287 AAEREETQQK-VQDLETRN-AELEHQLRAMERSLEEARAERERARAEVGR 334
>gi|222831612 solute carrier family 44, member 2 isoform 1 [Homo
sapiens]
Length = 706
Score = 30.0 bits (66), Expect = 8.9
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 14/93 (15%)
Query: 603 TWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANC---QAPRRPW-----LASHMSTVFLT 654
TWL F +L +++I +LL+ +++K L+A +A R L + T FL
Sbjct: 314 TWLA--FMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLL 371
Query: 655 LLCFPAFLGAAVFLC---YAVWQVKPSSTCGPF 684
LC + AVFL AV+++ S C PF
Sbjct: 372 CLCIAYWASTAVFLSTSNEAVYKIFDDSPC-PF 403
>gi|222831610 solute carrier family 44, member 2 isoform 2 [Homo
sapiens]
Length = 704
Score = 30.0 bits (66), Expect = 8.9
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 14/93 (15%)
Query: 603 TWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANC---QAPRRPW-----LASHMSTVFLT 654
TWL F +L +++I +LL+ +++K L+A +A R L + T FL
Sbjct: 312 TWLA--FMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLL 369
Query: 655 LLCFPAFLGAAVFLC---YAVWQVKPSSTCGPF 684
LC + AVFL AV+++ S C PF
Sbjct: 370 CLCIAYWASTAVFLSTSNEAVYKIFDDSPC-PF 401
>gi|21918872 lactation elevated 1 [Homo sapiens]
Length = 481
Score = 30.0 bits (66), Expect = 8.9
Identities = 32/142 (22%), Positives = 59/142 (41%), Gaps = 20/142 (14%)
Query: 27 ESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGSS--------QQTLWRPEGTQSTAT 78
E+ + F +L Q+Q+ T L++Q RE + + ++ RP G
Sbjct: 304 EAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASDYLE 363
Query: 79 LR------ILASMP-----SRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNFVRSAWPS 127
L L ++P +RT GR +I +Y+ V++ C +S P+ F+ S
Sbjct: 364 LSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQHHDS 423
Query: 128 -LRLYDLELDPTALEEEEKQSL 148
L + +D L ++ + L
Sbjct: 424 ELEQSRILMDDLGLSQDSAEGL 445
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,265,966
Number of Sequences: 37866
Number of extensions: 1404678
Number of successful extensions: 6005
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 5928
Number of HSP's gapped (non-prelim): 40
length of query: 805
length of database: 18,247,518
effective HSP length: 110
effective length of query: 695
effective length of database: 14,082,258
effective search space: 9787169310
effective search space used: 9787169310
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.