Guide to the Human Genome
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Search of human proteins with 100913209

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|100913209 heat shock transcription factor 4 isoform b [Homo
sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|100913209 heat shock transcription factor 4 isoform b [Homo s...  1000   0.0  
gi|100913211 heat shock transcription factor 4 isoform a [Homo s...   826   0.0  
gi|5031767 heat shock transcription factor 1 [Homo sapiens]           284   1e-76
gi|207113147 heat shock transcription factor 2 isoform b [Homo s...   193   3e-49
gi|4758568 heat shock transcription factor 2 isoform a [Homo sap...   193   3e-49
gi|122937277 heat shock transcription factor family member 5 [Ho...    60   3e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    55   2e-07
gi|239752444 PREDICTED: similar to heat shock transcription fact...    51   3e-06
gi|239746964 PREDICTED: similar to heat shock transcription fact...    51   3e-06
gi|50312655 heat shock transcription factor, Y-linked 1 isoform ...    50   4e-06
gi|32526913 heat shock transcription factor, Y linked 2 isoform ...    50   4e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   2e-05
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    47   5e-05
gi|169216697 PREDICTED: heat shock transcription factor family, ...    46   9e-05
gi|7706603 heat shock transcription factor family, X linked 1 [H...    46   9e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    45   2e-04
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    44   3e-04
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    44   3e-04
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    44   3e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      42   0.001
gi|41281612 zinc finger protein 828 [Homo sapiens]                     42   0.001
gi|146219832 myosin light chain kinase 3 [Homo sapiens]                42   0.001
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    42   0.002
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    42   0.002
gi|24211017 heat shock transcription factor, Y-linked 1 isoform ...    42   0.002
gi|50312659 heat shock transcription factor, Y linked 2 isoform ...    42   0.002
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    41   0.002
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    41   0.002
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    41   0.002
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    41   0.002

>gi|100913209 heat shock transcription factor 4 isoform b [Homo
           sapiens]
          Length = 492

 Score = 1000 bits (2585), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP 60
           MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
Sbjct: 1   MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP 60

Query: 61  QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK 120
           QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
Sbjct: 61  QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK 120

Query: 121 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ 180
           VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
Sbjct: 121 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ 180

Query: 181 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF 240
           QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
Sbjct: 181 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF 240

Query: 241 IQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPG 300
           IQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPG
Sbjct: 241 IQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPG 300

Query: 301 GDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD 360
           GDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD
Sbjct: 301 GDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD 360

Query: 361 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ 420
           RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ
Sbjct: 361 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ 420

Query: 421 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT 480
           PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT
Sbjct: 421 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT 480

Query: 481 ASYLGPEASPSP 492
           ASYLGPEASPSP
Sbjct: 481 ASYLGPEASPSP 492


>gi|100913211 heat shock transcription factor 4 isoform a [Homo
           sapiens]
          Length = 462

 Score =  826 bits (2133), Expect = 0.0
 Identities = 426/492 (86%), Positives = 431/492 (87%), Gaps = 30/492 (6%)

Query: 1   MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP 60
           MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
Sbjct: 1   MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP 60

Query: 61  QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK 120
           QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
Sbjct: 61  QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK 120

Query: 121 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ 180
           VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
Sbjct: 121 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ 180

Query: 181 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF 240
           QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
Sbjct: 181 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF 240

Query: 241 IQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPG 300
           IQSP   +   LS  +     ++     S       L P       +G   L   P   G
Sbjct: 241 IQSP---STYSLSQRQIWALALTGPGAPSSLTSQKTLHPL------RGPGFL--PPVMAG 289

Query: 301 GDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD 360
                              APPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD
Sbjct: 290 -------------------APPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD 330

Query: 361 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ 420
           RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ
Sbjct: 331 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ 390

Query: 421 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT 480
           PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT
Sbjct: 391 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT 450

Query: 481 ASYLGPEASPSP 492
           ASYLGPEASPSP
Sbjct: 451 ASYLGPEASPSP 462


>gi|5031767 heat shock transcription factor 1 [Homo sapiens]
          Length = 529

 Score =  284 bits (727), Expect = 1e-76
 Identities = 193/465 (41%), Positives = 255/465 (54%), Gaps = 38/465 (8%)

Query: 9   PTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNM 68
           P   GPS VPAFL KLW LV DP TD LI WSPSG SF V DQ +FAKEVLP+YFKH+NM
Sbjct: 7   PGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNM 66

Query: 69  ASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPA---LR 125
           ASFVRQLNMYGFRKVV IEQGGL++PERD  EFQHP F+RG+EQLLE ++RKV +   L+
Sbjct: 67  ASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLK 126

Query: 126 GDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQQHRVI 185
            +D + R + + +LL +VQ ++G QE  +++L  ++ +NE LWREV +LRQ H QQ +V+
Sbjct: 127 SEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVV 186

Query: 186 GKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQDPYFIQSP 244
            KLIQ L   +Q+     G KRK+ LML D GS+   P       L       PY   SP
Sbjct: 187 NKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPYSAPSP 245

Query: 245 LPETNLGLSPH--RARGPIISDIPEDSPSPEGTRLSPSSDGR--REKGLALLKEEP---- 296
              ++   +P    + GPIISDI E +P+        S D R      L  +KEEP    
Sbjct: 246 AYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEEPPSPP 305

Query: 297 -------ASPGGDGEAGLALAPNE-CDFCVTAPPPLPVAVVQAILEGKGSFSPEG----P 344
                  ASPG        L+P    D  +    P P A V A+ + +G    EG    P
Sbjct: 306 QSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAP-ASVTALTDARGHTDTEGRPPSP 364

Query: 345 RNAQQPEPG------DPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVL 398
                PE        D  E+ D     L++ D + ++L    +L     SV+ +  LD+ 
Sbjct: 365 PPTSTPEKCLSVACLDKNELSDH----LDAMDSNLDNL--QTMLSSHGFSVDTSALLDLF 418

Query: 399 GPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGK 443
            PS+   + +L DLD  L+ +Q L+  +  P       +SP  GK
Sbjct: 419 SPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGK 463


>gi|207113147 heat shock transcription factor 2 isoform b [Homo
           sapiens]
          Length = 518

 Score =  193 bits (490), Expect = 3e-49
 Identities = 102/201 (50%), Positives = 140/201 (69%), Gaps = 3/201 (1%)

Query: 15  SPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQ 74
           S VPAFL KLW LV +  T+  I WS +G SFLV D+ RFAKE+LP+YFKH+NMASFVRQ
Sbjct: 5   SNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQ 64

Query: 75  LNMYGFRKVVSIEQGGLLRPERD-HVEFQHPSFVRGREQLLERVRRKVPALRGDDGRWRP 133
           LNMYGFRKVV I+  G+++ ERD  VEFQHP F +G++ LLE ++RKV + + ++ + R 
Sbjct: 65  LNMYGFRKVVHID-SGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQ 123

Query: 134 EDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQQHRVIGKLIQCLF 193
           EDL +++   Q ++  QE+ E+RL EL+ +NE LW+EV  LR  H QQ +VI K++Q + 
Sbjct: 124 EDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIV 183

Query: 194 GPLQAGPSNAGGKRKLSLMLD 214
             +Q        KRK  L+L+
Sbjct: 184 TLVQ-NNQLVSLKRKRPLLLN 203


>gi|4758568 heat shock transcription factor 2 isoform a [Homo
           sapiens]
          Length = 536

 Score =  193 bits (490), Expect = 3e-49
 Identities = 102/201 (50%), Positives = 140/201 (69%), Gaps = 3/201 (1%)

Query: 15  SPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQ 74
           S VPAFL KLW LV +  T+  I WS +G SFLV D+ RFAKE+LP+YFKH+NMASFVRQ
Sbjct: 5   SNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQ 64

Query: 75  LNMYGFRKVVSIEQGGLLRPERD-HVEFQHPSFVRGREQLLERVRRKVPALRGDDGRWRP 133
           LNMYGFRKVV I+  G+++ ERD  VEFQHP F +G++ LLE ++RKV + + ++ + R 
Sbjct: 65  LNMYGFRKVVHID-SGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQ 123

Query: 134 EDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQQHRVIGKLIQCLF 193
           EDL +++   Q ++  QE+ E+RL EL+ +NE LW+EV  LR  H QQ +VI K++Q + 
Sbjct: 124 EDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIV 183

Query: 194 GPLQAGPSNAGGKRKLSLMLD 214
             +Q        KRK  L+L+
Sbjct: 184 TLVQ-NNQLVSLKRKRPLLLN 203


>gi|122937277 heat shock transcription factor family member 5 [Homo
           sapiens]
          Length = 596

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 49/136 (36%), Positives = 62/136 (45%), Gaps = 23/136 (16%)

Query: 6   AALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVL------ 59
           A L T   P+  PA   KLW LV  P     IRW   G   L+ DQ  F  E+L      
Sbjct: 3   ALLSTPINPNNFPA---KLWRLVNSPRY-RSIRWDGRGEGLLI-DQPLFEAELLSPPGPG 57

Query: 60  -----------PQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHV-EFQHPSFV 107
                      P+ FK ++  SF+RQLN+YGFRKVV    GG        +  F +P F 
Sbjct: 58  GGGGTAGAGAEPELFKTTSFTSFIRQLNLYGFRKVVLGGPGGGKPAGNGPLHHFHNPHFR 117

Query: 108 RGREQLLERVRRKVPA 123
           R + QLL  ++R   A
Sbjct: 118 RDQPQLLVHLKRLTSA 133


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 88/317 (27%), Positives = 125/317 (39%), Gaps = 56/317 (17%)

Query: 209  LSLMLDEGSSCPTPAKFNTCPLPGALLQDPYFIQ-------SPLPETNLGLSPHRARGPI 261
            LS   +E    P P +   C +P    ++P+          SP PE  L LSP +   P 
Sbjct: 761  LSPQAEEPHLSPQPEEPCLCAVP----EEPHLSPQAEGPHLSPQPE-ELHLSP-QTEEPH 814

Query: 262  ISDIPED---SPSPEGTRLSPSSDGR------REKGLAL-LKEEPASPGGDG---EAGLA 308
            +S +PE+   SP PE + LSP S+         E  L+  L++ P SP  +    E G  
Sbjct: 815  LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQC 874

Query: 309  LAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDP--REIPDRGPLGL 366
             AP E       PPP           G+ S SP     A   EPG+P    +P+  PL  
Sbjct: 875  PAPEELPLF---PPP-----------GEPSLSPLLGEPALS-EPGEPPLSPLPEELPLSP 919

Query: 367  ESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGP--SLQGREWTLMDLDMELSLMQPLV- 423
                     L+PP  L PP   +  A     L P   L+       D D E  L  P++ 
Sbjct: 920  SGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILE 979

Query: 424  ------PERG--EPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYST 475
                  PE    +PE     +  PSPG      +P+L++       P   L  +L   ++
Sbjct: 980  TPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPL--LQHSLVPQNS 1037

Query: 476  PESRTASYLGPEASPSP 492
            P S+ +    P + PSP
Sbjct: 1038 PPSQCSPPALPLSVPSP 1054



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 76/287 (26%), Positives = 106/287 (36%), Gaps = 25/287 (8%)

Query: 220 PTPAKFNTCPLPGALLQDPYFIQSPLPETNLGLSPHRARGPIISDIPEDSPS---PEGTR 276
           P P +    PL  A +Q    +++PL E  + L P     P+ S  PE+SP+   PE +R
Sbjct: 409 PGPLQCEAKPLGKAGVQLEPQLEAPLNE-EMPLLPPPEESPL-SPPPEESPTSPPPEASR 466

Query: 277 LSPSSDGRREKGL--AL-----LKEEPASPGGDGEAGLALAPNECDFCVTAPPPL----- 324
           LSP  +      L  AL     L+E P SP  + E+ L+  P    F      PL     
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPE-ESPLSPPPESSPFSPLEESPLSPPEE 525

Query: 325 --PVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLL 382
             P   ++  L      SP  P   + P    P E+P   P   E+   SP     PM  
Sbjct: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP--PEASRLSPPPEESPMSP 583

Query: 383 QPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPG 442
            P +  + P      L P  +  E  L     E  L  P    R  P      + SP P 
Sbjct: 584 PPEESPMSPPPEASRLFPPFE--ESPLSPPPEESPLSPPPEASRLSPPPEDSPM-SPPPE 640

Query: 443 KDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRTASYLGPEAS 489
           + P    P +  +        L  P   +  S P   + +   PEAS
Sbjct: 641 ESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 78/293 (26%), Positives = 104/293 (35%), Gaps = 63/293 (21%)

Query: 208 KLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYFIQSPL---PETNLGLSPHRARGPIISD 264
           +LS   ++  + P P      P P   L      +SPL   PE    L P R+ GP +S 
Sbjct: 688 RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ-LCP-RSEGPHLSP 745

Query: 265 IPED---SPSPEGTRLSPSSDGRREKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAP 321
            PE+   SP PE   LSP ++   E  L+   EEP                    C+ A 
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAE---EPHLSPQPEEP--------------------CLCAV 782

Query: 322 PPLPVAVVQAILEGKGSFSPEGPRNAQQPEP---GDPREIPDRGPLGLESGDRSPESLLP 378
           P  P    QA          EGP  + QPE        E P   P+        PE   P
Sbjct: 783 PEEPHLSPQA----------EGPHLSPQPEELHLSPQTEEPHLSPV--------PEE--P 822

Query: 379 PMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNS 438
            +  QP +  + P      L P  +       +  +   L +P +  R E      G   
Sbjct: 823 CLSPQPEESHLSPQSEEPCLSPRPE-------ESHLSPELEKPPLSPRPEKPPEEPG-QC 874

Query: 439 PSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRTASYLG-PEASP 490
           P+P + P    P    +   LG PAL  PG   +   PE    S  G P  SP
Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 289  LALLKEEPASPGGDGEAGLALAPNECDFC-VTAPPPLPVAVVQAILEGKGSFSPEGPRNA 347
            L+LLK+E  +P    +       +  D   ++APPP   +   + L    +  P  P   
Sbjct: 4876 LSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVE 4935

Query: 348  QQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGP 394
               EP     +P   PL L S   SPES  P    +PP+E  +   P
Sbjct: 4936 LPTEPLAEPPVPS--PLPLAS---SPESARPKPRARPPEEGEDSRPP 4977


>gi|239752444 PREDICTED: similar to heat shock transcription factor
           family, X linked 1 [Homo sapiens]
          Length = 354

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 33/107 (30%), Positives = 57/107 (53%), Gaps = 11/107 (10%)

Query: 19  AFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQ-----YFKHSNMASFVR 73
           +F  KLW +V +  T   + W+  G + ++ D+  F +EVL +      FK  ++ SF+R
Sbjct: 82  SFPRKLWTIV-EEDTFKSVSWNDDGDAVII-DKDLFQREVLQRKGAERIFKTDSLTSFIR 139

Query: 74  QLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK 120
           QLN+YGF K       G     +  + + + +F R + +LLE ++RK
Sbjct: 140 QLNLYGFCKTRPSNSPG----NKKMMIYCNSNFQRDKPRLLENIQRK 182


>gi|239746964 PREDICTED: similar to heat shock transcription factor
           family, X linked 1 [Homo sapiens]
          Length = 333

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 33/107 (30%), Positives = 57/107 (53%), Gaps = 11/107 (10%)

Query: 19  AFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQ-----YFKHSNMASFVR 73
           +F  KLW +V +  T   + W+  G + ++ D+  F +EVL +      FK  ++ SF+R
Sbjct: 82  SFPRKLWTIV-EEDTFKSVSWNDDGDAVII-DKDLFQREVLQRKGAERIFKTDSLTSFIR 139

Query: 74  QLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK 120
           QLN+YGF K       G     +  + + + +F R + +LLE ++RK
Sbjct: 140 QLNLYGFCKTRPSNSPG----NKKMMIYCNSNFQRDKPRLLENIQRK 182


>gi|50312655 heat shock transcription factor, Y-linked 1 isoform 1
           [Homo sapiens]
          Length = 401

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 18/118 (15%)

Query: 20  FLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP-----QYFKHSNMASFVRQ 74
           F  KLW +V +      I W  +GT  +++++  F KE+L      + F+   + SFVRQ
Sbjct: 80  FPRKLWKIV-ESDQFKSISWDENGTCIVINEEL-FKKEILETKAPYRIFQTDAIKSFVRQ 137

Query: 75  LNMYGFRKVVSIEQ-----GGLLRPERDHVE------FQHPSFVRGREQLLERVRRKV 121
           LN+YGF K+    Q        L  E++         + +P+F RG  QLL RV+R++
Sbjct: 138 LNLYGFSKIQQNFQRSAFLATFLSEEKESSVLSKLKFYYNPNFKRGYPQLLVRVKRRI 195


>gi|32526913 heat shock transcription factor, Y linked 2 isoform 1
           [Homo sapiens]
          Length = 401

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 18/118 (15%)

Query: 20  FLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP-----QYFKHSNMASFVRQ 74
           F  KLW +V +      I W  +GT  +++++  F KE+L      + F+   + SFVRQ
Sbjct: 80  FPRKLWKIV-ESDQFKSISWDENGTCIVINEEL-FKKEILETKAPYRIFQTDAIKSFVRQ 137

Query: 75  LNMYGFRKVVSIEQ-----GGLLRPERDHVE------FQHPSFVRGREQLLERVRRKV 121
           LN+YGF K+    Q        L  E++         + +P+F RG  QLL RV+R++
Sbjct: 138 LNLYGFSKIQQNFQRSAFLATFLSEEKESSVLSKLKFYYNPNFKRGYPQLLVRVKRRI 195


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 74/291 (25%), Positives = 96/291 (32%), Gaps = 50/291 (17%)

Query: 228 CPLPGALLQDPYFIQSPLPET--NLGLSPHRARGPIISDIPEDSPSPEGTRL-SPSSDGR 284
           CP P  L   P  + +P PET  ++   P +A   + S   +  PSP  + L +P     
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622

Query: 285 REKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGP 344
               L  L+  P+ P     + LA          T  P  P A+   +L+   S  P  P
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPLA----------TPSPQAPNALAVHLLQAPFSPPPSPP 672

Query: 345 RNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVE----------PAGP 394
             A    P  P   P   P       ++P SL  P L  PP               P  P
Sbjct: 673 VQAPFSPPASPPVSPSATP-----PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727

Query: 395 LDVLGPSLQGREWTLMDLDMELSLMQP------------LVPERGEPELAVKGLNSPSPG 442
             +  P LQ          M  S   P             VP      L +  L  P P 
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787

Query: 443 KDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRTASY-LGPEASPSP 492
             P L  P L     AL  P    PG       P S +AS  + P A+P P
Sbjct: 788 APPALATPPL----QALPSPPASFPG-----QAPFSPSASLPMSPLATPPP 829



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 67/306 (21%), Positives = 97/306 (31%), Gaps = 48/306 (15%)

Query: 200 PSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYFIQSPLPETNLGLSPHRARG 259
           PS  GG ++ +      S+ P  +   + P      + P     P P+    L P +   
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287

Query: 260 PIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPGGDGEAGLALAPNECDFCVT 319
           P     P   P       +PS  G         K  P  P  +    L           T
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSG--------TKARPVPPPDNAATPLP---------AT 330

Query: 320 APPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPP 379
            PP  P+A    +     S  P     + Q  P  P   P + P         P    PP
Sbjct: 331 LPPSPPLATPLPLAPPSPSAPP-----SLQTLPSPPATPPSQAP---------PSMTTPP 376

Query: 380 MLLQPPQESVEPAG-PLDVLGPSLQG--REWTLMDLDMELSLMQP----------LVPER 426
           M   P  +++ P   P  +  PSLQ       L  L    SL  P          + P +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436

Query: 427 GEPELAVKGLNSPSPGKDPTLGAPLLL----DVQAALGGPALGLPGALTIYSTPESRTAS 482
            +  L      + +P   P L APL L     +Q +L      L   LTI+      + +
Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496

Query: 483 YLGPEA 488
              P+A
Sbjct: 497 SHSPQA 502



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 63/266 (23%), Positives = 86/266 (32%), Gaps = 53/266 (19%)

Query: 233 ALLQDPYFIQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALL 292
           +L+  P   QS L   +L   P     P + ++P  +P P  T  +P +    E      
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565

Query: 293 K---EEPASPGGDGEAGLALAPNECDFCVTAPPP-LPVAVVQAILEGKGSFSPEGPRNAQ 348
               + P SP       L   P E    +  PPP  P A+    L+G  S          
Sbjct: 566 PCPLQAPPSP-------LTTPPPETPSSIATPPPQAPPALASPPLQGLPS---------- 608

Query: 349 QPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWT 408
                     P   PL        P   LPP+   P   +  P  PL    PS Q     
Sbjct: 609 ----------PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT--PSPQAPNAL 656

Query: 409 LMDLDMELSLMQPLVPERGEPELAVKGLNSP--SPGKDPTLGAPLLLDVQAALGGPALGL 466
            + L     L  P  P    P   V+   SP  SP   P+   P       +L  P L +
Sbjct: 657 AVHL-----LQAPFSPPPSPP---VQAPFSPPASPPVSPSATPP--SQAPPSLAAPPLQV 706

Query: 467 PGALTIYSTPESRTASYLGPEASPSP 492
           P        P    +  + P A+P P
Sbjct: 707 P--------PSPPASPPMSPSATPPP 724


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 76/283 (26%), Positives = 101/283 (35%), Gaps = 37/283 (13%)

Query: 209  LSLMLDEGSSCPTPAKFNT--CPLPGALLQDPYFIQSPLPETNLGLSPHRARGPIISDIP 266
            LS +L   SS P P    +   P P A +              LG S   +  P+++ + 
Sbjct: 871  LSPLLPSSSSSPPPGACGSPSAPTPSAGVAATTIAGFGHFHKALGGSLSSSDSPLLTPLQ 930

Query: 267  EDSPSPEGTRLSPSSDGRREKGLALLKE---------EPASPGGD-----GEAGLALAPN 312
              + SP+  + SP+  G R  GL L +           P+S  G      GE  L LA  
Sbjct: 931  PGARSPQAAQPSPAPPGARG-GLGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATG 989

Query: 313  ECDFCVTAP-PPLPVAVVQAILEGKG--SFSPEGPRNAQQPEPGDPREIPDRGPLGLESG 369
                  T P  P P ++V     G     F+P G  +     PG PR  P   P    SG
Sbjct: 990  PLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPGPPRTFPSAPPRA--SG 1047

Query: 370  DRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEP 429
                  LLPP    PP +  +  G      P   GR     DL + +S  QP +P+ G  
Sbjct: 1048 SHG-SLLLPPASSPPPPQVPQRRG----TPPLTPGR--LTQDLKL-ISASQPALPQDGAQ 1099

Query: 430  ELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGP----ALGLPG 468
             L      SP    +     PL        GG      LG PG
Sbjct: 1100 TLR---RASPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPG 1139


>gi|169216697 PREDICTED: heat shock transcription factor family, X
           linked 2 [Homo sapiens]
          Length = 423

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 16/116 (13%)

Query: 20  FLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKH-----SNMASFVRQ 74
           F  KLW LV        I W  SG   +++ Q  F KE+L +   H     +++ SF RQ
Sbjct: 99  FPQKLWRLVSSNQFSS-IWWDDSGACRVIN-QKLFEKEILKRDVAHKVFATTSIKSFFRQ 156

Query: 75  LNMYGFRK--------VVSIEQGGLLRPERDHVEFQ-HPSFVRGREQLLERVRRKV 121
           LN+YGFRK           I     L    + +EF  HP F R    LL R++R+V
Sbjct: 157 LNLYGFRKRRQCTFRTFTRIFSAKRLVSILNKLEFYCHPYFQRDSPHLLVRMKRRV 212


>gi|7706603 heat shock transcription factor family, X linked 1 [Homo
           sapiens]
          Length = 423

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 16/116 (13%)

Query: 20  FLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKH-----SNMASFVRQ 74
           F  KLW LV        I W  SG   +++ Q  F KE+L +   H     +++ SF RQ
Sbjct: 99  FPQKLWRLVSSNQFSS-IWWDDSGACRVIN-QKLFEKEILKRDVAHKVFATTSIKSFFRQ 156

Query: 75  LNMYGFRK--------VVSIEQGGLLRPERDHVEFQ-HPSFVRGREQLLERVRRKV 121
           LN+YGFRK           I     L    + +EF  HP F R    LL R++R+V
Sbjct: 157 LNLYGFRKRRQCTFRTFTRIFSAKRLVSILNKLEFYCHPYFQRDSPHLLVRMKRRV 212


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 73/312 (23%), Positives = 94/312 (30%), Gaps = 52/312 (16%)

Query: 221 TPAKFNTCPLPGALLQDPYFIQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPS 280
           TP + +  P  G L   P    SP         P  +  P +  +P    +P     +  
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSP------SAPPSPSAPPSLQTLPSPPATPPSQATTSL 330

Query: 281 SDGRREKGLALLKEEP----ASPGGDGEAGLALAPNECDFCVTAPPPL----------PV 326
                +   + L   P    A+P       LAL P +      A PPL          P 
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390

Query: 327 AVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQ 386
           A+   +L+   S  P  P  A    P  P   P   P       ++P SL  P L  PP 
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP-----PSQAPPSLAAPPLQVPPS 445

Query: 387 ESVEP-----------------AGPLDVLGPSLQGREWT----LMDLDMELSLMQPLVPE 425
               P                 A PL +  P  Q         L  L    +      P 
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505

Query: 426 RGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPAL------GLPGALTIYSTPESR 479
                L +  L +P P   P L APLL    +    P L        PG  T  S P   
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 565

Query: 480 TASYLGPEASPS 491
            A   GP   PS
Sbjct: 566 LALAPGPPPPPS 577



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 72/304 (23%), Positives = 99/304 (32%), Gaps = 45/304 (14%)

Query: 200 PSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYFIQSPLPETNLGLSPHRARG 259
           P   G ++ +S   +  ++ P+PA     P  G  LQ P         T L  SP R+  
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRR-PSAGGGLQRPASRSLSSSATPLS-SPARS-- 246

Query: 260 PIISDIPEDSPSPEGTRLSPSSDGR-REKGLALLKEEPASPGGDGEAGLALAPNECDFCV 318
                     PS  GT  +P+   + + KGL  L+    +P    +A  AL P       
Sbjct: 247 ---------GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-DAAPALGPLSSSPLA 296

Query: 319 TAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPR--------EIPDRGPLGLESGD 370
           T  P  P +             P  P +      G P           P   PL      
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356

Query: 371 RSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPE 430
             P   LPP+   P   +  P  PL    PS Q      + L     L  P  P    P 
Sbjct: 357 APPALALPPLQAPPSPPASPPLSPLAT--PSPQAPNALAVHL-----LQAPFSPPPSPP- 408

Query: 431 LAVKGLNSP--SPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRTASYLGPEA 488
             V+   SP  SP   P+   P       +L  P L +P        P    +  + P A
Sbjct: 409 --VQAPFSPPASPPVSPSATPP--SQAPPSLAAPPLQVP--------PSPPASPPMSPSA 456

Query: 489 SPSP 492
           +P P
Sbjct: 457 TPPP 460


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
           sapiens]
          Length = 1751

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 77/272 (28%), Positives = 99/272 (36%), Gaps = 63/272 (23%)

Query: 247 ETNLGLSPHRARGPIISDIP-------EDSPSPE----------GTRLSPSSD------- 282
           ET   L P     P ++  P       EDS S E          G +  P SD       
Sbjct: 680 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 739

Query: 283 ------GR-REKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVV------ 329
                 GR +E GL   K EP  PG  G AG   +P     C+  PP LP  V       
Sbjct: 740 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP-----CLPGPPGLPCPVSPLGPAG 794

Query: 330 QAILEGKGSFSPEGPRN-----AQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQP 384
            A+    G   P GP        +  EPGDP E    G  G +    +P  + P      
Sbjct: 795 PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGD 854

Query: 385 P----QESVEPAGPLDVLGPSLQGREWTLMDLDME--LSLMQPLVPERGEPELAVKGLNS 438
           P    +    P GP    GPS +  + T +D++       ++ L   RG P         
Sbjct: 855 PGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFP-------GP 907

Query: 439 PSPGKDPTL-GAPLLLDVQAA-LGGPALGLPG 468
           P P   P L G P    V ++ + GPA GLPG
Sbjct: 908 PGPPGVPGLPGEPGRFGVNSSDVPGPA-GLPG 938



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 14/115 (12%)

Query: 286  EKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPR 345
            ++G A  K E   PGG G  G +L           PP  P       + G     P+G  
Sbjct: 1329 DRGDAGQKGERGEPGGGGFFGSSLP---------GPPGPPGPRGYPGIPG-----PKGES 1374

Query: 346  NAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGP 400
               QP P  P+  P  G  G +     P    PP    P ++++   GP    GP
Sbjct: 1375 IRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGP 1429



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 69/258 (26%), Positives = 81/258 (31%), Gaps = 71/258 (27%)

Query: 254  PHRARGPIISDIPEDSPSPEGTRLSPSSDGRREK-------GLALLKEEPASPGGDGEAG 306
            P R   P    +P   P P G    P   G++         G    K  P   G  GE+G
Sbjct: 940  PGREGPPGFPGLP-GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG 998

Query: 307  LALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDR----G 362
            LA AP        A PP             G   P GP     P PG P    D     G
Sbjct: 999  LAGAPG------PAGPP-------------GPPGPPGP-----PGPGLPAGFDDMEGSGG 1034

Query: 363  PLGLES----GDRSPESLLPPMLLQPPQESVEPAGPLDVLG------PSLQGREWTLMDL 412
            P    +    G + P  L  P L   P     P    +V        P L GRE      
Sbjct: 1035 PFWSTARSADGPQGPPGL--PGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGRE------ 1086

Query: 413  DMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTI 472
                 +  P  P+        KG     PGKD  +G P        L GP  G PG +  
Sbjct: 1087 ----GIAGPQGPKGDRGSRGEKG----DPGKD-GVGQP-------GLPGPP-GPPGPVVY 1129

Query: 473  YSTPESRTASYLGPEASP 490
             S  +    S  GPE  P
Sbjct: 1130 VSEQDGSVLSVPGPEGRP 1147


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 77/272 (28%), Positives = 99/272 (36%), Gaps = 63/272 (23%)

Query: 247 ETNLGLSPHRARGPIISDIP-------EDSPSPE----------GTRLSPSSD------- 282
           ET   L P     P ++  P       EDS S E          G +  P SD       
Sbjct: 265 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 324

Query: 283 ------GR-REKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVV------ 329
                 GR +E GL   K EP  PG  G AG   +P     C+  PP LP  V       
Sbjct: 325 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP-----CLPGPPGLPCPVSPLGPAG 379

Query: 330 QAILEGKGSFSPEGPRN-----AQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQP 384
            A+    G   P GP        +  EPGDP E    G  G +    +P  + P      
Sbjct: 380 PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGD 439

Query: 385 P----QESVEPAGPLDVLGPSLQGREWTLMDLDME--LSLMQPLVPERGEPELAVKGLNS 438
           P    +    P GP    GPS +  + T +D++       ++ L   RG P         
Sbjct: 440 PGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFP-------GP 492

Query: 439 PSPGKDPTL-GAPLLLDVQAA-LGGPALGLPG 468
           P P   P L G P    V ++ + GPA GLPG
Sbjct: 493 PGPPGVPGLPGEPGRFGVNSSDVPGPA-GLPG 523



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 14/115 (12%)

Query: 286  EKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPR 345
            ++G A  K E   PGG G  G +L           PP  P       + G     P+G  
Sbjct: 914  DRGDAGQKGERGEPGGGGFFGSSLP---------GPPGPPGPRGYPGIPG-----PKGES 959

Query: 346  NAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGP 400
               QP P  P+  P  G  G +     P    PP    P ++++   GP    GP
Sbjct: 960  IRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGP 1014



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 69/258 (26%), Positives = 81/258 (31%), Gaps = 71/258 (27%)

Query: 254 PHRARGPIISDIPEDSPSPEGTRLSPSSDGRREK-------GLALLKEEPASPGGDGEAG 306
           P R   P    +P   P P G    P   G++         G    K  P   G  GE+G
Sbjct: 525 PGREGPPGFPGLP-GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG 583

Query: 307 LALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDR----G 362
           LA AP        A PP             G   P GP     P PG P    D     G
Sbjct: 584 LAGAPG------PAGPP-------------GPPGPPGP-----PGPGLPAGFDDMEGSGG 619

Query: 363 PLGLES----GDRSPESLLPPMLLQPPQESVEPAGPLDVLG------PSLQGREWTLMDL 412
           P    +    G + P  L  P L   P     P    +V        P L GRE      
Sbjct: 620 PFWSTARSADGPQGPPGL--PGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGRE------ 671

Query: 413 DMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTI 472
                +  P  P+        KG     PGKD  +G P        L GP  G PG +  
Sbjct: 672 ----GIAGPQGPKGDRGSRGEKG----DPGKD-GVGQP-------GLPGPP-GPPGPVVY 714

Query: 473 YSTPESRTASYLGPEASP 490
            S  +    S  GPE  P
Sbjct: 715 VSEQDGSVLSVPGPEGRP 732


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1516

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 77/272 (28%), Positives = 99/272 (36%), Gaps = 63/272 (23%)

Query: 247 ETNLGLSPHRARGPIISDIP-------EDSPSPE----------GTRLSPSSD------- 282
           ET   L P     P ++  P       EDS S E          G +  P SD       
Sbjct: 445 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 504

Query: 283 ------GR-REKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVV------ 329
                 GR +E GL   K EP  PG  G AG   +P     C+  PP LP  V       
Sbjct: 505 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP-----CLPGPPGLPCPVSPLGPAG 559

Query: 330 QAILEGKGSFSPEGPRN-----AQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQP 384
            A+    G   P GP        +  EPGDP E    G  G +    +P  + P      
Sbjct: 560 PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGD 619

Query: 385 P----QESVEPAGPLDVLGPSLQGREWTLMDLDME--LSLMQPLVPERGEPELAVKGLNS 438
           P    +    P GP    GPS +  + T +D++       ++ L   RG P         
Sbjct: 620 PGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFP-------GP 672

Query: 439 PSPGKDPTL-GAPLLLDVQAA-LGGPALGLPG 468
           P P   P L G P    V ++ + GPA GLPG
Sbjct: 673 PGPPGVPGLPGEPGRFGVNSSDVPGPA-GLPG 703



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 14/115 (12%)

Query: 286  EKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPR 345
            ++G A  K E   PGG G  G +L           PP  P       + G     P+G  
Sbjct: 1094 DRGDAGQKGERGEPGGGGFFGSSLP---------GPPGPPGPRGYPGIPG-----PKGES 1139

Query: 346  NAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGP 400
               QP P  P+  P  G  G +     P    PP    P ++++   GP    GP
Sbjct: 1140 IRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGP 1194



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 69/258 (26%), Positives = 81/258 (31%), Gaps = 71/258 (27%)

Query: 254 PHRARGPIISDIPEDSPSPEGTRLSPSSDGRREK-------GLALLKEEPASPGGDGEAG 306
           P R   P    +P   P P G    P   G++         G    K  P   G  GE+G
Sbjct: 705 PGREGPPGFPGLP-GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG 763

Query: 307 LALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDR----G 362
           LA AP        A PP             G   P GP     P PG P    D     G
Sbjct: 764 LAGAPG------PAGPP-------------GPPGPPGP-----PGPGLPAGFDDMEGSGG 799

Query: 363 PLGLES----GDRSPESLLPPMLLQPPQESVEPAGPLDVLG------PSLQGREWTLMDL 412
           P    +    G + P  L  P L   P     P    +V        P L GRE      
Sbjct: 800 PFWSTARSADGPQGPPGL--PGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGRE------ 851

Query: 413 DMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTI 472
                +  P  P+        KG     PGKD  +G P        L GP  G PG +  
Sbjct: 852 ----GIAGPQGPKGDRGSRGEKG----DPGKD-GVGQP-------GLPGPP-GPPGPVVY 894

Query: 473 YSTPESRTASYLGPEASP 490
            S  +    S  GPE  P
Sbjct: 895 VSEQDGSVLSVPGPEGRP 912


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 20/119 (16%)

Query: 266 PEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPG------GDGEAGLALAPNECDFCVT 319
           P+  P   G   +P   G R  GL   +  P +PG       DG  G A  P        
Sbjct: 285 PKGEPGSPGENGAPGQMGPR--GLPGERGRPGAPGPAGARGNDGATGAAGPPGPTG--PA 340

Query: 320 APPPLPVAVVQAILEGKGSFSPEGPRNAQQP-----EPGDPREIPDRGPLGLESGDRSP 373
            PP  P AV       KG   P+GPR ++ P     EPG P      GP G    D  P
Sbjct: 341 GPPGFPGAV-----GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQP 394



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 72/240 (30%), Positives = 92/240 (38%), Gaps = 31/240 (12%)

Query: 269 SPSPEGTRLSPSSDGRREK----GLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPL 324
           SP P G + SP   GR  +    G   L   P SPG DG+ G    P   D     PP  
Sbjct: 513 SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG-PPGPAGQD-GRPGPPGP 570

Query: 325 PVAVVQAILEG----KGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPM 380
           P A  QA + G    KG+    G +  ++  PG P  +   G  G E+G + P     P 
Sbjct: 571 PGARGQAGVMGFPGPKGAAGEPG-KAGERGVPGPPGAVGPAGKDG-EAGAQGPPGPAGPA 628

Query: 381 LLQPPQESV---------EPAGPLDVLG-PSLQGREWTLMDLDMELSLMQPLVPERGEP- 429
             +  Q             PAGP    G P  QG     +  D+          ERG P 
Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQG-----VPGDLGAPGPSGARGERGFPG 683

Query: 430 ELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGP-ALGLPGALTIYSTPESRTASYL-GPE 487
           E  V+G   P+ G     GAP     +   G P A G  GA  +   P  R A+ L GP+
Sbjct: 684 ERGVQGPPGPA-GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPK 742



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 33/101 (32%), Positives = 40/101 (39%), Gaps = 16/101 (15%)

Query: 295  EPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGD 354
            E  SPG DG AG   AP         P P  +A  + ++   G     G        PG 
Sbjct: 933  EKGSPGADGPAG---APG-------TPGPQGIAGQRGVVGLPGQRGERGFPGL----PGP 978

Query: 355  PREIPDRGPLGLESGDRSPESLL-PPMLLQPPQESVEPAGP 394
              E   +GP G  SG+R P   + PP L  PP ES     P
Sbjct: 979  SGEPGKQGPSGA-SGERGPPGPMGPPGLAGPPGESGREGAP 1018



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 42/137 (30%), Positives = 48/137 (35%), Gaps = 23/137 (16%)

Query: 257 ARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEP------ASPGGDGEAGLALA 310
           ARGP     P   P P+G    P + G   KG    K EP        PG  GE G   A
Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPG--SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471

Query: 311 PNECDFCVTAPPP----------LPVAVVQAILEG----KGSFSPEGPRNAQQPEPGDPR 356
             E        PP           P A   A  +G    +GS  P GP+ +   E G P 
Sbjct: 472 RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS-PGEAGRPG 530

Query: 357 EIPDRGPLGLESGDRSP 373
           E    G  GL     SP
Sbjct: 531 EAGLPGAKGLTGSPGSP 547


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 35/161 (21%), Positives = 59/161 (36%), Gaps = 8/161 (4%)

Query: 242 QSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPAS--P 299
           +SP P     L P +    +  ++    PSPE ++ +  S     K + + + +  +  P
Sbjct: 144 ESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVP 203

Query: 300 GGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIP 359
             + +    ++P      ++ P P   +     L    + SPE P  A  PEP  P    
Sbjct: 204 SPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGP---- 259

Query: 360 DRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGP 400
              P       +S  +  P      P ES EP  P   + P
Sbjct: 260 --SPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSP 298


>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
          Length = 819

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 39/210 (18%)

Query: 194 GPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYFIQSPLPETNLGLS 253
           GP QA P +     K+     E  S          P PG +      + SP    +L ++
Sbjct: 231 GPAQAFPGHLPLPTKVEAKAPETPSENLRTGLELAPAPGRVN-----VVSP----SLEVA 281

Query: 254 PHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPGGDGEAGLALAPNE 313
           P   +G   S  P+  P  EGTRL+P                P  PG  G    A A + 
Sbjct: 282 PGAGQGAS-SSRPDPEPLEEGTRLTPGPG-------------PQCPGPPGLPAQARATHS 327

Query: 314 CDFCVTAPPPLPVAVV------QAILEGKGSFSP----EGPRNAQQPEPGDPREIPDRGP 363
                  PP + + +       + ++ G+GS  P    E P  AQ  + G P        
Sbjct: 328 GG---ETPPRISIHIQEMDTPGEMLMTGRGSLGPTLTTEAPAAAQPGKQGPPGTGRCLQA 384

Query: 364 LGLESGDRSPESLLPPMLLQPPQESVEPAG 393
            G E G+++PE       L P QES  P G
Sbjct: 385 PGTEPGEQTPEGARE---LSPLQESSSPGG 411


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 62/237 (26%), Positives = 79/237 (33%), Gaps = 31/237 (13%)

Query: 217 SSCPTPAKFNTCPLPGALLQDPYFIQSPLPETNLGL--SPHRARGPIISDIPEDSPSPEG 274
           S  P P +    P    +   P  I  P+P T   +  SPH    P +   P   PSP  
Sbjct: 159 SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ-PSPGP 217

Query: 275 TRLSPSSDGRREKGLA--LLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAI 332
           T   P   G R   L    +++ P S          L P         PPP P  V    
Sbjct: 218 T--PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRP 275

Query: 333 LEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPA 392
              + +  P  P+N + P P  PR               S  S  PP    PP     P 
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRP--------------SASSQAPP----PPPPPSRPG 317

Query: 393 GPLDVLGPSLQGREWT--LMDLDMELSLMQPLVPERGE--PELAVKGLNSPSPGKDP 445
            P   L PS  G + T  L   ++ LS   P +P  G   P         P P +DP
Sbjct: 318 PP--PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372



 Score = 35.8 bits (81), Expect = 0.091
 Identities = 70/274 (25%), Positives = 90/274 (32%), Gaps = 56/274 (20%)

Query: 195 PLQAGPSNAG------GKRKLSLMLDEGSSCPTPAKF----NTCPLPGALLQDPYFIQSP 244
           P+Q+ P N G      G R       + S  PTP  F     T    G++ Q P    SP
Sbjct: 193 PIQSSPHNRGSPPVPGGPR-------QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245

Query: 245 LPETN-LGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPGGDG 303
                 L  +P RA    + D P   P P G R  PS              +P  P    
Sbjct: 246 FSNRPPLPPTPSRA----LDDKPPPPPPPVGNR--PSIHREAVPPPPPQNNKPPVPSTPR 299

Query: 304 EAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPR----NAQQPEPGDPREIP 359
            +  + AP         PPP P       L    S + E PR    N        P   P
Sbjct: 300 PSASSQAP--------PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP 351

Query: 360 DR-GPLGLESGDRSPESLLPPMLLQPPQES--VEPAGPLDVLGPSLQGREWTLMDLDMEL 416
            R GPL     +R P     P +  PP  S  + P  P+   G + +    T        
Sbjct: 352 GRSGPLPPPPSERPP-----PPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT-------- 398

Query: 417 SLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAP 450
               P +P R   +    G   P P   P+ GAP
Sbjct: 399 ----PQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 62/237 (26%), Positives = 79/237 (33%), Gaps = 31/237 (13%)

Query: 217 SSCPTPAKFNTCPLPGALLQDPYFIQSPLPETNLGL--SPHRARGPIISDIPEDSPSPEG 274
           S  P P +    P    +   P  I  P+P T   +  SPH    P +   P   PSP  
Sbjct: 159 SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ-PSPGP 217

Query: 275 TRLSPSSDGRREKGLA--LLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAI 332
           T   P   G R   L    +++ P S          L P         PPP P  V    
Sbjct: 218 T--PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRP 275

Query: 333 LEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPA 392
              + +  P  P+N + P P  PR               S  S  PP    PP     P 
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRP--------------SASSQAPP----PPPPPSRPG 317

Query: 393 GPLDVLGPSLQGREWT--LMDLDMELSLMQPLVPERGE--PELAVKGLNSPSPGKDP 445
            P   L PS  G + T  L   ++ LS   P +P  G   P         P P +DP
Sbjct: 318 PP--PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372



 Score = 35.8 bits (81), Expect = 0.091
 Identities = 70/274 (25%), Positives = 90/274 (32%), Gaps = 56/274 (20%)

Query: 195 PLQAGPSNAG------GKRKLSLMLDEGSSCPTPAKF----NTCPLPGALLQDPYFIQSP 244
           P+Q+ P N G      G R       + S  PTP  F     T    G++ Q P    SP
Sbjct: 193 PIQSSPHNRGSPPVPGGPR-------QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245

Query: 245 LPETN-LGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPGGDG 303
                 L  +P RA    + D P   P P G R  PS              +P  P    
Sbjct: 246 FSNRPPLPPTPSRA----LDDKPPPPPPPVGNR--PSIHREAVPPPPPQNNKPPVPSTPR 299

Query: 304 EAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPR----NAQQPEPGDPREIP 359
            +  + AP         PPP P       L    S + E PR    N        P   P
Sbjct: 300 PSASSQAP--------PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP 351

Query: 360 DR-GPLGLESGDRSPESLLPPMLLQPPQES--VEPAGPLDVLGPSLQGREWTLMDLDMEL 416
            R GPL     +R P     P +  PP  S  + P  P+   G + +    T        
Sbjct: 352 GRSGPLPPPPSERPP-----PPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT-------- 398

Query: 417 SLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAP 450
               P +P R   +    G   P P   P+ GAP
Sbjct: 399 ----PQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428


>gi|24211017 heat shock transcription factor, Y-linked 1 isoform 2
           [Homo sapiens]
          Length = 203

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 7/69 (10%)

Query: 20  FLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP-----QYFKHSNMASFVRQ 74
           F  KLW +V +      I W  +GT  +++++  F KE+L      + F+   + SFVRQ
Sbjct: 80  FPRKLWKIV-ESDQFKSISWDENGTCIVINEEL-FKKEILETKAPYRIFQTDAIKSFVRQ 137

Query: 75  LNMYGFRKV 83
           LN+YGF K+
Sbjct: 138 LNLYGFSKI 146


>gi|50312659 heat shock transcription factor, Y linked 2 isoform 2
           [Homo sapiens]
          Length = 203

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 7/69 (10%)

Query: 20  FLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP-----QYFKHSNMASFVRQ 74
           F  KLW +V +      I W  +GT  +++++  F KE+L      + F+   + SFVRQ
Sbjct: 80  FPRKLWKIV-ESDQFKSISWDENGTCIVINEEL-FKKEILETKAPYRIFQTDAIKSFVRQ 137

Query: 75  LNMYGFRKV 83
           LN+YGF K+
Sbjct: 138 LNLYGFSKI 146


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 77/344 (22%), Positives = 103/344 (29%), Gaps = 56/344 (16%)

Query: 195 PLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF------IQSPLPET 248
           P Q  P        L  +     + P+P+       P  L   P+       + +PLP  
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA 341

Query: 249 NLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEP----ASPGGDGE 304
                P  +  P +  +P    +P     +       +   + L   P    A+P     
Sbjct: 342 ----PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397

Query: 305 AGLALAPNECDFCVTAPPPL----------PVAVVQAILEGKGSFSPEGPRNAQQPEPGD 354
             LAL P +      A PPL          P A+   +L+   S  P  P  A    P  
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457

Query: 355 PREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEP-----------------AGPLDV 397
           P   P   P       ++P SL  P L  PP     P                 A PL +
Sbjct: 458 PPVSPSATP-----PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512

Query: 398 LGPSLQGREWT----LMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAPLLL 453
             P  Q         L  L    +      P      L +  L +P P   P L APLL 
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572

Query: 454 DVQAALGGPAL------GLPGALTIYSTPESRTASYLGPEASPS 491
              +    P L        PG  T  S P    A   GP   PS
Sbjct: 573 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 58/192 (30%), Positives = 70/192 (36%), Gaps = 40/192 (20%)

Query: 270 PSPEGTRLSPSSDGRREKGLALLKEEPAS---PGGDGEAGLALAPNECDFCVTAPPPLPV 326
           P P G R  P   G  EKG    + EP     PG DGE G    P      +   P  P 
Sbjct: 269 PGPPGIRGPPGPPGG-EKGEKGEQGEPGKRGKPGKDGENGQPGIPG-----LPGDPGYPG 322

Query: 327 AVVQAILEG-KGSFSPEGPRNAQQPEPGDPREIPDRGPLGL-----ESGDRS-PESLLPP 379
              +   +G KG   P GP     P PG    I ++G +GL     E G+R  P    PP
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPP 382

Query: 380 MLLQPPQESV-EPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNS 438
            L  PP  +V  P GP     P   G      D               G P +++ G   
Sbjct: 383 GLPGPPGAAVMGPPGP-----PGFPGERGQKGD--------------EGPPGISIPG--- 420

Query: 439 PSPGKDPTLGAP 450
             PG D   GAP
Sbjct: 421 -PPGLDGQPGAP 431



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 61/226 (26%), Positives = 79/226 (34%), Gaps = 31/226 (13%)

Query: 270  PSPEGTRLSPSSDGRREKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVV 329
            P  +G +  P        GL   K EP  PG  G  G+  +    D  +   P  P A  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG--DPGLPGLPGTPGAKG 1116

Query: 330  QAILEG-KGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQES 388
            Q  L G  G+  P GP+    P PG+P    + GP+G       P          PP E 
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISGP-PGNPGLPGEPGPVGGGGHPGQP---------GPPGEK 1166

Query: 389  VEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEP-ELAVKGLNSPSPGKDPTL 447
             +P G   + GP+ Q  E              P  P  G P    + GL S   G     
Sbjct: 1167 GKP-GQDGIPGPAGQKGE--------------PGQPGFGNPGPPGLPGL-SGQKGDGGLP 1210

Query: 448  GAPLLLDVQAALGGPAL-GLPGALTIYSTPESRTASYLGPEASPSP 492
            G P    +    G P   G PG       P S   +  GP+ +P P
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 58/192 (30%), Positives = 70/192 (36%), Gaps = 40/192 (20%)

Query: 270 PSPEGTRLSPSSDGRREKGLALLKEEPAS---PGGDGEAGLALAPNECDFCVTAPPPLPV 326
           P P G R  P   G  EKG    + EP     PG DGE G    P      +   P  P 
Sbjct: 269 PGPPGIRGPPGPPGG-EKGEKGEQGEPGKRGKPGKDGENGQPGIPG-----LPGDPGYPG 322

Query: 327 AVVQAILEG-KGSFSPEGPRNAQQPEPGDPREIPDRGPLGL-----ESGDRS-PESLLPP 379
              +   +G KG   P GP     P PG    I ++G +GL     E G+R  P    PP
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPP 382

Query: 380 MLLQPPQESV-EPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNS 438
            L  PP  +V  P GP     P   G      D               G P +++ G   
Sbjct: 383 GLPGPPGAAVMGPPGP-----PGFPGERGQKGD--------------EGPPGISIPG--- 420

Query: 439 PSPGKDPTLGAP 450
             PG D   GAP
Sbjct: 421 -PPGLDGQPGAP 431



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 61/226 (26%), Positives = 79/226 (34%), Gaps = 31/226 (13%)

Query: 270  PSPEGTRLSPSSDGRREKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVV 329
            P  +G +  P        GL   K EP  PG  G  G+  +    D  +   P  P A  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG--DPGLPGLPGTPGAKG 1116

Query: 330  QAILEG-KGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQES 388
            Q  L G  G+  P GP+    P PG+P    + GP+G       P          PP E 
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISGP-PGNPGLPGEPGPVGGGGHPGQP---------GPPGEK 1166

Query: 389  VEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEP-ELAVKGLNSPSPGKDPTL 447
             +P G   + GP+ Q  E              P  P  G P    + GL S   G     
Sbjct: 1167 GKP-GQDGIPGPAGQKGE--------------PGQPGFGNPGPPGLPGL-SGQKGDGGLP 1210

Query: 448  GAPLLLDVQAALGGPAL-GLPGALTIYSTPESRTASYLGPEASPSP 492
            G P    +    G P   G PG       P S   +  GP+ +P P
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 36/132 (27%), Positives = 47/132 (35%), Gaps = 35/132 (26%)

Query: 269  SPSPEGTRLSPSSDGRR-EKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVA 327
            +P P G    P   G++ + GL  +   P  PG  GE G    P      V  PP  P +
Sbjct: 1191 NPGPPGL---PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG-----VQGPPGPPGS 1242

Query: 328  VVQAILEGKGSFSPEGPR-------------------------NAQQPE-PGDPREIPDR 361
               A+   KG+  P+GP                          N  QP  PG P    D+
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1302

Query: 362  GPLGLESGDRSP 373
            GP GL+     P
Sbjct: 1303 GPPGLQGNPGRP 1314


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 58/192 (30%), Positives = 70/192 (36%), Gaps = 40/192 (20%)

Query: 270 PSPEGTRLSPSSDGRREKGLALLKEEPAS---PGGDGEAGLALAPNECDFCVTAPPPLPV 326
           P P G R  P   G  EKG    + EP     PG DGE G    P      +   P  P 
Sbjct: 269 PGPPGIRGPPGPPGG-EKGEKGEQGEPGKRGKPGKDGENGQPGIPG-----LPGDPGYPG 322

Query: 327 AVVQAILEG-KGSFSPEGPRNAQQPEPGDPREIPDRGPLGL-----ESGDRS-PESLLPP 379
              +   +G KG   P GP     P PG    I ++G +GL     E G+R  P    PP
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPP 382

Query: 380 MLLQPPQESV-EPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNS 438
            L  PP  +V  P GP     P   G      D               G P +++ G   
Sbjct: 383 GLPGPPGAAVMGPPGP-----PGFPGERGQKGD--------------EGPPGISIPG--- 420

Query: 439 PSPGKDPTLGAP 450
             PG D   GAP
Sbjct: 421 -PPGLDGQPGAP 431



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 61/226 (26%), Positives = 79/226 (34%), Gaps = 31/226 (13%)

Query: 270  PSPEGTRLSPSSDGRREKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVV 329
            P  +G +  P        GL   K EP  PG  G  G+  +    D  +   P  P A  
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG--DPGLPGLPGTPGAKG 1116

Query: 330  QAILEG-KGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQES 388
            Q  L G  G+  P GP+    P PG+P    + GP+G       P          PP E 
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISGP-PGNPGLPGEPGPVGGGGHPGQP---------GPPGEK 1166

Query: 389  VEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEP-ELAVKGLNSPSPGKDPTL 447
             +P G   + GP+ Q  E              P  P  G P    + GL S   G     
Sbjct: 1167 GKP-GQDGIPGPAGQKGE--------------PGQPGFGNPGPPGLPGL-SGQKGDGGLP 1210

Query: 448  GAPLLLDVQAALGGPAL-GLPGALTIYSTPESRTASYLGPEASPSP 492
            G P    +    G P   G PG       P S   +  GP+ +P P
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.137    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,824,813
Number of Sequences: 37866
Number of extensions: 1675124
Number of successful extensions: 5937
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 396
Number of HSP's that attempted gapping in prelim test: 5347
Number of HSP's gapped (non-prelim): 981
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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