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Search of human proteins with 100913206
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo
sapiens]
(1270 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 2581 0.0
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 508 e-143
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 484 e-136
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 460 e-129
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 450 e-126
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 405 e-112
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 405 e-112
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 310 4e-84
gi|166851804 tudor domain containing 9 [Homo sapiens] 309 1e-83
gi|38505213 YTH domain containing 2 [Homo sapiens] 268 3e-71
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 258 3e-68
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 256 1e-67
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 251 4e-66
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 251 4e-66
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 243 6e-64
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 228 3e-59
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 185 3e-46
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 157 6e-38
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 157 6e-38
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 133 9e-31
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 116 1e-25
gi|55956899 keratin 9 [Homo sapiens] 95 4e-19
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 89 3e-17
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 89 3e-17
gi|195972866 keratin 10 [Homo sapiens] 86 2e-16
gi|109452587 family with sequence similarity 98, member B isofor... 86 3e-16
gi|119395750 keratin 1 [Homo sapiens] 84 1e-15
gi|109255251 loricrin [Homo sapiens] 74 7e-13
gi|109148552 keratin 3 [Homo sapiens] 73 2e-12
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 72 3e-12
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 2581 bits (6691), Expect = 0.0
Identities = 1270/1270 (100%), Positives = 1270/1270 (100%)
Query: 1 MGDVKNFLYAWCGKRKMTPSYEIRAVGNKNRQKFMCEVQVEGYNYTGMGNSTNKKDAQSN 60
MGDVKNFLYAWCGKRKMTPSYEIRAVGNKNRQKFMCEVQVEGYNYTGMGNSTNKKDAQSN
Sbjct: 1 MGDVKNFLYAWCGKRKMTPSYEIRAVGNKNRQKFMCEVQVEGYNYTGMGNSTNKKDAQSN 60
Query: 61 AARDFVNYLVRINEIKSEEVPAFGVASPPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK 120
AARDFVNYLVRINEIKSEEVPAFGVASPPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK
Sbjct: 61 AARDFVNYLVRINEIKSEEVPAFGVASPPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK 120
Query: 121 AENNSEVGASGYGVPGPTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLEN 180
AENNSEVGASGYGVPGPTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLEN
Sbjct: 121 AENNSEVGASGYGVPGPTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLEN 180
Query: 181 AKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQ 240
AKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQ
Sbjct: 181 AKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQ 240
Query: 241 SCALSLVRQLYHLGVVEAYSGLTKKKEGETVEPYKVNLSQDLEHQLQNIIQELNLEILPP 300
SCALSLVRQLYHLGVVEAYSGLTKKKEGETVEPYKVNLSQDLEHQLQNIIQELNLEILPP
Sbjct: 241 SCALSLVRQLYHLGVVEAYSGLTKKKEGETVEPYKVNLSQDLEHQLQNIIQELNLEILPP 300
Query: 301 PEDPSVPVALNIGKLAQFEPSQRQNQVGVVPWSPPQSNWNPWTSSNIDEGPLAFATPEQI 360
PEDPSVPVALNIGKLAQFEPSQRQNQVGVVPWSPPQSNWNPWTSSNIDEGPLAFATPEQI
Sbjct: 301 PEDPSVPVALNIGKLAQFEPSQRQNQVGVVPWSPPQSNWNPWTSSNIDEGPLAFATPEQI 360
Query: 361 SMDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQ 420
SMDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQ
Sbjct: 361 SMDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQ 420
Query: 421 VPQFILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILP 480
VPQFILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILP
Sbjct: 421 VPQFILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILP 480
Query: 481 RPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIV 540
RPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIV
Sbjct: 481 RPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIV 540
Query: 541 LMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDG 600
LMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDG
Sbjct: 541 LMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDG 600
Query: 601 GEDDDANCNLICGDEYGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGW 660
GEDDDANCNLICGDEYGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGW
Sbjct: 601 GEDDDANCNLICGDEYGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGW 660
Query: 661 NLIYTMQKHLEMNPHFGSHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSI 720
NLIYTMQKHLEMNPHFGSHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSI
Sbjct: 661 NLIYTMQKHLEMNPHFGSHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSI 720
Query: 721 TINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRA 780
TINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRA
Sbjct: 721 TINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRA 780
Query: 781 RFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELD 840
RFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELD
Sbjct: 781 RFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELD 840
Query: 841 ALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRL 900
ALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRL
Sbjct: 841 ALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRL 900
Query: 901 GYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQL 960
GYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQL
Sbjct: 901 GYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQL 960
Query: 961 KEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNA 1020
KEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNA
Sbjct: 961 KEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNA 1020
Query: 1021 LIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ 1080
LIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ
Sbjct: 1021 LIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ 1080
Query: 1081 IVLVDDWIKLQISHEAAACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISR 1140
IVLVDDWIKLQISHEAAACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISR
Sbjct: 1081 IVLVDDWIKLQISHEAAACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISR 1140
Query: 1141 PSAAGINLMIGSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYG 1200
PSAAGINLMIGSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYG
Sbjct: 1141 PSAAGINLMIGSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYG 1200
Query: 1201 GSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGY 1260
GSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGY
Sbjct: 1201 GSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGY 1260
Query: 1261 FGQGRGGGGY 1270
FGQGRGGGGY
Sbjct: 1261 FGQGRGGGGY 1270
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 508 bits (1308), Expect = e-143
Identities = 303/787 (38%), Positives = 449/787 (57%), Gaps = 47/787 (5%)
Query: 365 KNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQF 424
KN+L Y +E H RE LP + E++ I + V +I G TGCGKTTQV QF
Sbjct: 192 KNDLRY-IEMQHF-------REKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQF 243
Query: 425 ILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEE--PGKSCGYSVRFESILPRP 482
ILD++I+ + + C IV TQPRRISA+SVAERVA ER E G S GY +R +S LPR
Sbjct: 244 ILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRK 303
Query: 483 HASIMFCTVGVLLRKLEAG--IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIV 540
SI++CT G++L+ L++ + +SH+++DEIHER++ +D L+ V++D++ +++++
Sbjct: 304 QGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVI 363
Query: 541 LMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDK---- 596
LMSAT++ F EYF NCP+I + G T+PV EY LED I+ +VP K+ + + K
Sbjct: 364 LMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFM 423
Query: 597 ----DDDGGEDDDANCNLICGD-------EYGPETRLSMSQLNEKETPFELIEALLKYIE 645
+ E+ +A D Y T + + + + LI AL++YI
Sbjct: 424 QGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIV 483
Query: 646 TLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGSHRYQILPLHSQIPREEQRKVFDPVPVG 705
GA+LVFLPGW+ I T+ L F S ++ I+PLHS +P Q +VF P G
Sbjct: 484 LEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPG 543
Query: 706 VTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRA 765
V K++++TNIAETSITI+DVVYVID K K F NN++ + W SK N +QRKGRA
Sbjct: 544 VRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRA 603
Query: 766 GRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPP 825
GRV+PG C+HL + R L+ + PE+ RTPL E+ L IK+LRLGGI FL++ ++PP
Sbjct: 604 GRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPS 663
Query: 826 LDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAA 885
+AV+ + L EL+ALD +ELTPLG LA+LP+EP GKM++ G +F D + TIAA
Sbjct: 664 NEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAA 723
Query: 886 ATCFPEPFI---NEGKRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEH 942
+ F +PF+ + K + A + SDH+ +++ F+ W++AR G E +C
Sbjct: 724 SLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWE 783
Query: 943 KRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPN 1002
L+ TL+M K Q E L+ +GF +N DN ++ +++ G+YP
Sbjct: 784 YFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNE-KIIKAVICAGLYPK 842
Query: 1003 VCYHK----EKRKIL----TTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAI 1054
V + +KRK++ T+G A +H SVN D Y + ++ K+RT +I
Sbjct: 843 VAKIRLNLGKKRKMVKVYTKTDGLVA-VHPKSVN--VEQTDFHY--NWLIYHLKMRTSSI 897
Query: 1055 SAKGMTLVTPLQLLLFA---SKKVQSDGQIVLVDDWIKLQISHEAAACITGLRAAMEALV 1111
T V+P LL F S + +D + + VD+WI Q A + LR ++ L+
Sbjct: 898 YLYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILL 957
Query: 1112 VEVTKQP 1118
E + P
Sbjct: 958 QEKIESP 964
Score = 44.7 bits (104), Expect = 6e-04
Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 1174 RRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGD 1233
R GG SGGGYGGG +GG+GG+ S G G G G G RG G +G G
Sbjct: 11 RDGGPRSSGGGYGGG------PAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIGM 64
Query: 1234 YRGPSGGYR 1242
+ G +
Sbjct: 65 WYAKKQGQK 73
Score = 37.7 bits (86), Expect = 0.070
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 1224 GGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGG 1268
GG R + GG GP+GG+ G+ G GGG G G G G+GR G
Sbjct: 13 GGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG--GRGRHPG 55
Score = 35.8 bits (81), Expect = 0.27
Identities = 24/51 (47%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 1183 GGYGGGYSS-GGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGG 1232
G GG SS GGYG G GG + +G G G GGG RG RG G+ G
Sbjct: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG-GRGRHPGHLKG 59
Score = 35.0 bits (79), Expect = 0.46
Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 7/57 (12%)
Query: 1198 GYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRG 1254
G G S GYG G GG+ GG RG+ GG G GG RG G G +G
Sbjct: 10 GRDGGPRSSGGGYGGGPAGGH-----GGNRGSGGGG--GGGGGGRGGRGRHPGHLKG 59
Score = 34.3 bits (77), Expect = 0.78
Identities = 23/55 (41%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 1199 YGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGR 1253
Y N R G GGGY G GG GN RG GG G GG + G GR
Sbjct: 3 YDYHQNWGRDGGPRSSGGGYGGGPAGGHGGN-----RGSGGGGGGGGGGRGGRGR 52
Score = 33.1 bits (74), Expect = 1.7
Identities = 18/34 (52%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 1236 GPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
G GG R SGG GG G +G G G G GGGG
Sbjct: 10 GRDGGPRSSGGGYGGGPAGGHG-GNRGSGGGGGG 42
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 484 bits (1247), Expect = e-136
Identities = 297/787 (37%), Positives = 439/787 (55%), Gaps = 61/787 (7%)
Query: 365 KNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQF 424
KN+L Y +E H RE LP + E++ I + V +I G TGCGKTTQV QF
Sbjct: 192 KNDLRY-IEMQHF-------REKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQF 243
Query: 425 ILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEE--PGKSCGYSVRFESILPRP 482
ILD++I+ + + C IV TQPRRISA+SVAERVA ER E G S GY +R +S LPR
Sbjct: 244 ILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRK 303
Query: 483 HASIMFCTVGVLLRKLEAG--IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIV 540
SI++CT G++L+ L++ + +SH+++DEIHER++ +D L+ V++D++ +++++
Sbjct: 304 QGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVI 363
Query: 541 LMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDK---- 596
LMSAT++ F EYF NCP+I + G T+PV EY LED I+ +VP K+ + + K
Sbjct: 364 LMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFM 423
Query: 597 ----DDDGGEDDDANCNLICGD-------EYGPETRLSMSQLNEKETPFELIEALLKYIE 645
+ E+ +A D Y T + + + + LI AL++YI
Sbjct: 424 QGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIV 483
Query: 646 TLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGSHRYQILPLHSQIPREEQRKVFDPVPVG 705
GA+LVFLPGW+ I T+ L F S Q +VF P G
Sbjct: 484 LEEEDGAILVFLPGWDNISTLHDLLMSQVMFKS--------------VNQTQVFKRTPPG 529
Query: 706 VTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRA 765
V K++++TNIAETSITI+DVVYVID K K F NN++ + W SK N +QRKGRA
Sbjct: 530 VRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRA 589
Query: 766 GRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPP 825
GRV+PG C+HL + R L+ + PE+ RTPL E+ L IK+LRLGGI FL++ ++PP
Sbjct: 590 GRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPS 649
Query: 826 LDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAA 885
+AV+ + L EL+ALD +ELTPLG LA+LP+EP GKM++ G +F D + TIAA
Sbjct: 650 NEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAA 709
Query: 886 ATCFPEPFI---NEGKRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEH 942
+ F +PF+ + K + A + SDH+ +++ F+ W++AR G E +C
Sbjct: 710 SLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWE 769
Query: 943 KRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPN 1002
L+ TL+M K Q E L+ +GF +N DN ++ +++ G+YP
Sbjct: 770 YFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNE-KIIKAVICAGLYPK 828
Query: 1003 VCYHK----EKRKIL----TTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAI 1054
V + +KRK++ T+G A +H SVN D Y + ++ K+RT +I
Sbjct: 829 VAKIRLNLGKKRKMVKVYTKTDGLVA-VHPKSVN--VEQTDFHY--NWLIYHLKMRTSSI 883
Query: 1055 SAKGMTLVTPLQLLLFA---SKKVQSDGQIVLVDDWIKLQISHEAAACITGLRAAMEALV 1111
T V+P LL F S + +D + + VD+WI Q A + LR ++ L+
Sbjct: 884 YLYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILL 943
Query: 1112 VEVTKQP 1118
E + P
Sbjct: 944 QEKIESP 950
Score = 44.7 bits (104), Expect = 6e-04
Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 1174 RRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGD 1233
R GG SGGGYGGG +GG+GG+ S G G G G G RG G +G G
Sbjct: 11 RDGGPRSSGGGYGGG------PAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIGM 64
Query: 1234 YRGPSGGYR 1242
+ G +
Sbjct: 65 WYAKKQGQK 73
Score = 37.7 bits (86), Expect = 0.070
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 1224 GGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGG 1268
GG R + GG GP+GG+ G+ G GGG G G G G+GR G
Sbjct: 13 GGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG--GRGRHPG 55
Score = 35.8 bits (81), Expect = 0.27
Identities = 24/51 (47%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 1183 GGYGGGYSS-GGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGG 1232
G GG SS GGYG G GG + +G G G GGG RG RG G+ G
Sbjct: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG-GRGRHPGHLKG 59
Score = 35.0 bits (79), Expect = 0.46
Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 7/57 (12%)
Query: 1198 GYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRG 1254
G G S GYG G GG+ GG RG+ GG G GG RG G G +G
Sbjct: 10 GRDGGPRSSGGGYGGGPAGGH-----GGNRGSGGGG--GGGGGGRGGRGRHPGHLKG 59
Score = 34.3 bits (77), Expect = 0.78
Identities = 23/55 (41%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 1199 YGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGR 1253
Y N R G GGGY G GG GN RG GG G GG + G GR
Sbjct: 3 YDYHQNWGRDGGPRSSGGGYGGGPAGGHGGN-----RGSGGGGGGGGGGRGGRGR 52
Score = 33.1 bits (74), Expect = 1.7
Identities = 18/34 (52%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 1236 GPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
G GG R SGG GG G +G G G G GGGG
Sbjct: 10 GRDGGPRSSGGGYGGGPAGGHG-GNRGSGGGGGG 42
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 460 bits (1183), Expect = e-129
Identities = 308/862 (35%), Positives = 454/862 (52%), Gaps = 110/862 (12%)
Query: 373 EQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQN 432
+ Q+ILQER+ LP + IL + ++ VV+I G TGCGKTTQ+PQFILDD +
Sbjct: 529 QASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNG 588
Query: 433 DRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVG 492
NI+ TQPRRISA+SVAERVA ER E G + GY +R ES+ +++CT G
Sbjct: 589 PPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSA-TRLLYCTTG 647
Query: 493 VLLRKLEA--GIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSM 550
VLLR+LE ++G+SH+IVDE+HER +DFLL+VL+D+V P ++++LMSAT++ +
Sbjct: 648 VLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAEL 707
Query: 551 FCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPP------------KDKKKKDKDD 598
F +YF +CP+I + GRT+PV ++FLED I +T +V K+K K ++
Sbjct: 708 FSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNR 767
Query: 599 DGGED--DDANCNLICGDEYG-----PETRLSMSQL------------------NEKETP 633
E+ +D +L D+ P+ +L QL + ++
Sbjct: 768 TAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVN 827
Query: 634 FELIEALLKYI---ETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFG---SHRYQILPLH 687
ELIEALL++I + PGA+LVFLPG I + + L+ N F S+R I PLH
Sbjct: 828 LELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLH 887
Query: 688 SQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTN 747
S + EEQ+ VF P GVTK+I+STNIAETSITI+DVVYVIDS K K K + A M +
Sbjct: 888 SSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMES 947
Query: 748 YATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARF-ERLETHMTPEMFRTPLHEIALSIK 806
+ S+ N QRKGRAGRV G CFHL + + +L PE+ R PL ++ L IK
Sbjct: 948 LEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIK 1007
Query: 807 LLRL---GGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPR 863
+L + + ++ IEPP D++ ++ LR+L AL ++ LTPLG LA LP++ R
Sbjct: 1008 ILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVR 1067
Query: 864 FGKMMIMGCIFYVGDAICTIAAATCFPEPFIN--------EGKRLGYIHRNFAGNRFSDH 915
GK+M+ G IF D TIAA+ F PF++ K+L + N SD+
Sbjct: 1068 IGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFAN------SDY 1121
Query: 916 VALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPEDCLL 975
+ALL ++ W + G A +C L+ L+ K Q E+L + GF + L
Sbjct: 1122 LALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLR 1181
Query: 976 TQ-----------VFTNTGPDNNLD-----VVISLLAFGVYPNVCYHKE----------- 1008
+ V TG + N + ++ ++L +YPNV K
Sbjct: 1182 AREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTG 1241
Query: 1009 ---------KRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGM 1059
+ K +T IH SSVN Q + SP+ ++ EKI+T + +
Sbjct: 1242 AVRMQPKSAELKFVTKNDGYVHIHPSSVN----YQVRHFDSPYLLYHEKIKTSRVFIRDC 1297
Query: 1060 TLVTPLQLLLFASKKVQSDGQ-----IVLVDDWIK-LQISHEAAACITGLRAAMEALVVE 1113
++V+ L+LF +V Q + L D WI+ + SH+ A + LR ++ L+ +
Sbjct: 1298 SMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQD 1357
Query: 1114 VTKQPAIISQLDPVNERMLNMI 1135
K P+I P R+++ I
Sbjct: 1358 KIKNPSIDLCTCPRGSRIISTI 1379
Score = 33.5 bits (75), Expect = 1.3
Identities = 23/53 (43%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 1203 ANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGA 1255
++S R G GGG +G SRGG G S SGG G GG GG R A
Sbjct: 2 SSSVRRKGKPGKGGG-KGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKA 53
Score = 33.1 bits (74), Expect = 1.7
Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 9/54 (16%)
Query: 1170 GSGYRRGGSSYSGGGYGG-GYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVS 1222
G + GG S GG GG ++S +GSGG GG G G GGG R S
Sbjct: 9 GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGG--------GGGGGGGNRKAS 54
Score = 32.3 bits (72), Expect = 3.0
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 1171 SGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSR 1223
S RR G GGG G SS G G GG ++ S +G G G GGG G +R
Sbjct: 3 SSVRRKGKPGKGGGKG---SSRG-GRGGRSHASKSHGSGGGGGGGGGGGGGNR 51
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 450 bits (1158), Expect = e-126
Identities = 302/900 (33%), Positives = 469/900 (52%), Gaps = 65/900 (7%)
Query: 291 QELNLEILPPPEDPSVPVALNIGKLAQFEPSQRQNQVGVVPWSP-PQSNWNPWTSSNIDE 349
+ELN P D + LN KL Q + Q+Q+ S P+ +W S D
Sbjct: 477 EELNKMETNKPRDLFIAKLLN--KLKQQQQQQQQHSENKRENSEDPEESWENLVSDE-DF 533
Query: 350 GPLAFATPEQISMDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVII 409
L+ + ++ L +L+ Q +L+ER+ LPV K I+E + ++ VV++
Sbjct: 534 SALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVV 593
Query: 410 RGATGCGKTTQVPQFILDDFIQND-RAAECNIVVTQPRRISAVSVAERVAFERGEEPGKS 468
G TG GK+TQVP F+L+D + N+ A++CNIV TQPRRISAVS+A RV E G E G
Sbjct: 594 AGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPG 653
Query: 469 -----CGYSVRFESILPRPHASIMFCTVGVLLRKLEAG--IRGISHVIVDEIHERDINTD 521
CGY +R ES +++CT GVLLRKL+ + +SHVIVDE+HER + +D
Sbjct: 654 GRNSLCGYQIRMESRACES-TRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSD 712
Query: 522 FLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQM 581
FLL++L++++Q ++ ++LMSAT+D+ F YF +CPI+ + GR+YPV+ + LED I+
Sbjct: 713 FLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEE 772
Query: 582 THFVPPPKDKKKKDKDDDGGEDDDANCNLICG-----------------------DEYGP 618
T FV KD + K + E+ N G +Y
Sbjct: 773 TGFV-LEKDSEYCQKFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSS 831
Query: 619 ETRLSMSQLNEKETPFELIEALLKYIET----LNVPGAVLVFLPGWNLIYTMQKHLEMNP 674
T+ ++ +N + +LI LL Y++ N+ GAVL+FLPG I + L +
Sbjct: 832 RTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDR 891
Query: 675 HFGSHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQ 734
F S RY+++ LHS + ++Q F P GV K++L+TNIAET ITI DVV+VID+ +
Sbjct: 892 RFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRT 951
Query: 735 KVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMF 794
K + + M++ + SK + QR+GRAGRVR GFCF + +R RFE + PE+
Sbjct: 952 KENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEIL 1011
Query: 795 RTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDAND-ELTPLGR 853
R PL E+ L I LG FL+KA++PP L + A + LR++ A + N+ +LTPLG+
Sbjct: 1012 RVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQ 1071
Query: 854 ILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINE--GKRLGYIHRNFAGNR 911
LA LP+ + GKM+I G IF D + T+AA PF K + ++
Sbjct: 1072 HLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMA 1131
Query: 912 FSDHVALLSVFQAWDDARM-GGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFP 970
SDH+ + + + W AR GG +EI +C LN +L + K +L +++ +GF
Sbjct: 1132 DSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFS 1191
Query: 971 EDCLLTQVFTNTGPD----NNLDVVISLLAFGVYPNV---CYHK-----EKRK-ILTTEG 1017
T N + ++ ++L G+Y NV Y K EK I+ T
Sbjct: 1192 SSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQ 1251
Query: 1018 RNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASK-KVQ 1076
A +H SSVN + + ++ EKIR + + TL+TP +LLF +VQ
Sbjct: 1252 GKAQVHPSSVNRDLQTHG------WLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQ 1305
Query: 1077 SDGQIVLVDDWIKLQISHEAAACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIR 1136
+++ +D WI Q + A LR +++++ + + P + + D + + + +I+
Sbjct: 1306 HRERLLSIDGWIYFQAPVKIAVIFKQLRVLIDSVLRKKLENPKMSLENDKILQIITELIK 1365
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo
sapiens]
Length = 1155
Score = 405 bits (1040), Expect = e-112
Identities = 251/735 (34%), Positives = 388/735 (52%), Gaps = 64/735 (8%)
Query: 381 ILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNI 440
+ QE LPV IL AI Q+ VV+I G TGCGKTT++PQ +L+ ++ R A CN+
Sbjct: 388 VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 447
Query: 441 VVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEA 500
++TQPRRISAVSVA+RV+ E G ++ G+ VR ES P +++FCTVG+LLRKL++
Sbjct: 448 IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 507
Query: 501 G--IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNC 558
+ G+SHVIVDE+HERD+NTDFLL++L+ + + P +R+VLMSAT D F YF C
Sbjct: 508 NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 567
Query: 559 PIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGP 618
P+I+V G YPV+E++LED + K K + + + C L
Sbjct: 568 PVIKVPGFMYPVKEHYLEDILA--------KLGKHQYLHRHRHHESEDECAL-------- 611
Query: 619 ETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGS 678
+L+ L+ +I+ PG +L FLPGW I +Q+ L+
Sbjct: 612 --------------DLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHE 657
Query: 679 HRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKL 738
+Y ILP+HS IP +Q+ +F PVGV K++L+TNIAETSITIND+V+V+DS K +
Sbjct: 658 SKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEER 717
Query: 739 FTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPL 798
+ ++ TVW S+ N+ QR+GRAGR + GF +HL R+R E++ PE+ RTPL
Sbjct: 718 YDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPL 777
Query: 799 HEIALSIKL-LRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAK 857
+ L K+ + +FL+KA++ P + AV EA L+E+ LD + LT LG+ LA
Sbjct: 778 ENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAH 837
Query: 858 LPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPF---INEGKRLGYIHRNFAGNRFSD 914
+ +PR K +++ IF + + + +PF + + + + + SD
Sbjct: 838 ISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSD 896
Query: 915 HVALLSVFQAWDDA-RMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINS---GFP 970
H+A + W++ R + + E L +LR Q E + + G P
Sbjct: 897 HLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKP 956
Query: 971 EDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCY-----------HKEKRKILTTEGRN 1019
DC L N + ++V +L G+YPN+ K T+ N
Sbjct: 957 SDCTLASAQCNEYSEEE-ELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGN 1015
Query: 1020 ALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTR-AISAKGMTLVTPLQLLLFASKKVQSD 1078
L+HKS++N + + S + + +++ ++ + + V PL +LL +D
Sbjct: 1016 ILLHKSTIN----REATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLL------TD 1065
Query: 1079 GQIVLVDDWIKLQIS 1093
G + + DD + IS
Sbjct: 1066 GDVHIRDDGRRATIS 1080
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo
sapiens]
Length = 1194
Score = 405 bits (1040), Expect = e-112
Identities = 251/735 (34%), Positives = 388/735 (52%), Gaps = 64/735 (8%)
Query: 381 ILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNI 440
+ QE LPV IL AI Q+ VV+I G TGCGKTT++PQ +L+ ++ R A CN+
Sbjct: 427 VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 486
Query: 441 VVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEA 500
++TQPRRISAVSVA+RV+ E G ++ G+ VR ES P +++FCTVG+LLRKL++
Sbjct: 487 IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 546
Query: 501 G--IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNC 558
+ G+SHVIVDE+HERD+NTDFLL++L+ + + P +R+VLMSAT D F YF C
Sbjct: 547 NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 606
Query: 559 PIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGP 618
P+I+V G YPV+E++LED + K K + + + C L
Sbjct: 607 PVIKVPGFMYPVKEHYLEDILA--------KLGKHQYLHRHRHHESEDECAL-------- 650
Query: 619 ETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGS 678
+L+ L+ +I+ PG +L FLPGW I +Q+ L+
Sbjct: 651 --------------DLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHE 696
Query: 679 HRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKL 738
+Y ILP+HS IP +Q+ +F PVGV K++L+TNIAETSITIND+V+V+DS K +
Sbjct: 697 SKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEER 756
Query: 739 FTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPL 798
+ ++ TVW S+ N+ QR+GRAGR + GF +HL R+R E++ PE+ RTPL
Sbjct: 757 YDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPL 816
Query: 799 HEIALSIKL-LRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAK 857
+ L K+ + +FL+KA++ P + AV EA L+E+ LD + LT LG+ LA
Sbjct: 817 ENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAH 876
Query: 858 LPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPF---INEGKRLGYIHRNFAGNRFSD 914
+ +PR K +++ IF + + + +PF + + + + + SD
Sbjct: 877 ISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSD 935
Query: 915 HVALLSVFQAWDDA-RMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINS---GFP 970
H+A + W++ R + + E L +LR Q E + + G P
Sbjct: 936 HLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKP 995
Query: 971 EDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCY-----------HKEKRKILTTEGRN 1019
DC L N + ++V +L G+YPN+ K T+ N
Sbjct: 996 SDCTLASAQCNEYSEEE-ELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGN 1054
Query: 1020 ALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTR-AISAKGMTLVTPLQLLLFASKKVQSD 1078
L+HKS++N + + S + + +++ ++ + + V PL +LL +D
Sbjct: 1055 ILLHKSTIN----REATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLL------TD 1104
Query: 1079 GQIVLVDDWIKLQIS 1093
G + + DD + IS
Sbjct: 1105 GDVHIRDDGRRATIS 1119
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
sapiens]
Length = 1143
Score = 310 bits (795), Expect = 4e-84
Identities = 209/614 (34%), Positives = 315/614 (51%), Gaps = 73/614 (11%)
Query: 378 LQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAE 437
L + +ER LP+ ++ + IL+ + ++ VV++ G TGCGK+TQVPQ++L A
Sbjct: 152 LAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL-------AAGF 204
Query: 438 CNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRK 497
++ TQPRRI+ +S+A+RV FE + G GY +RFES I+F TVG+LLR+
Sbjct: 205 SHVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAA-TKIVFLTVGLLLRQ 263
Query: 498 L--EAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYF 555
+ E + +IVDE+HER ++ DFLL VL+ ++ P+++++LMSATI+ S+F YF
Sbjct: 264 IQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYF 323
Query: 556 FNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDE 615
N P+++V GR +P+ + Q P +K D
Sbjct: 324 SNAPVVQVPGRLFPITVVY-----QPQEAEPTTSKSEKLDPR------------------ 360
Query: 616 YGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPH 675
P R+ + ++ K P E G +LVFL G I + LE
Sbjct: 361 --PFLRV-LESIDHKYPPEER--------------GDLLVFLSGMAEISAV---LEAAQT 400
Query: 676 FGSH--RYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCK 733
+ SH R+ +LPLHS + +Q KVFD P GV K ILSTNIAETS+TI+ + +V+DS K
Sbjct: 401 YASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGK 460
Query: 734 QKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEM 793
K + + W S+ + EQRKGRAGR PG CF L + + ++ + PE+
Sbjct: 461 VKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEI 520
Query: 794 FRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGR 853
R L + L +K + +G F IEPPP ++ A LR+ ALD+++ LTP+G
Sbjct: 521 RRVALDSLVLQMKSMSVGDPRTF--PFIEPPPPASLETAILYLRDQGALDSSEALTPIGS 578
Query: 854 ILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGK---RLGYIHRNFAGN 910
+LA+LP++ GKM+I+G +F + + + TIAAA PF + R +
Sbjct: 579 LLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLESD 638
Query: 911 RFSDHVALLSVFQAWDDARMGGEEAEIRFC------EHKRLNMATLRMTWEAKVQLKEIL 964
+ D L +VF AW + ++C EH+ MA LR Q KE+L
Sbjct: 639 Q-GDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMANLRR------QFKELL 691
Query: 965 INSGFPEDCLLTQV 978
+ G QV
Sbjct: 692 EDHGLLAGAQAAQV 705
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 309 bits (791), Expect = 1e-83
Identities = 214/572 (37%), Positives = 307/572 (53%), Gaps = 50/572 (8%)
Query: 388 LPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIVVTQPRR 447
LP+ +++ E++ I NSVVII GATG GK+TQ+PQ+ILD ++Q R+A C+IVVTQPR+
Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQ--RSAYCSIVVTQPRK 189
Query: 448 ISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAG--IRGI 505
I A S+A ++ ER G GY V E I +++ T GVLL+K+ + +
Sbjct: 190 IGASSIARWISKERAWTLGGVVGYQVGLEKIATED-TRLIYMTTGVLLQKIVSAKSLMEF 248
Query: 506 SHVIVDEIHERDINTDFLLVVLRDVVQAYPE-VRIVLMSATIDTSMFCEYFF-------- 556
+H+I+DE+HER DFLL+V+R +++ V++VLMSATI F +YF
Sbjct: 249 THIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMN 308
Query: 557 NCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEY 616
I EV G+ + V+EY+L D + H P ++ +I D Y
Sbjct: 309 PAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEP---------------VITKDIY 353
Query: 617 GPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHF 676
E +S+ Q+ + E + + +VLVFLPG I M + L H
Sbjct: 354 --EVAVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVH- 410
Query: 677 GSHRYQILPLHSQIPREEQRKVF-DPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQK 735
R Q+ PLHS + EEQ VF PVP G K+ILSTNIAE+S+T+ DV YVID C +
Sbjct: 411 --KRLQVYPLHSSVALEEQNNVFLSPVP-GYRKIILSTNIAESSVTVPDVKYVIDFCLTR 467
Query: 736 VKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFER-LETHMTPEMF 794
+ N + WASKT+ QRKGRAGRV G+C+ L + ++ + H+ PEM
Sbjct: 468 TLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEML 527
Query: 795 RTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDAL-------DAN-- 845
R PL L +KLL +G LA A+ PP L + L+E+ AL D N
Sbjct: 528 RCPLGSTILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPH 587
Query: 846 -DELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRL--GY 902
ELT LGR+LA+LP+ + GK++++G +F D IAAA F ++ GY
Sbjct: 588 DGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGY 647
Query: 903 IHR-NFAGNRFSDHVALLSVFQAWDDARMGGE 933
++ NF+G+ SD +AL+ F+ W R GE
Sbjct: 648 RNKVNFSGSSKSDCIALVEAFKTWKACRQTGE 679
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 268 bits (684), Expect = 3e-71
Identities = 208/611 (34%), Positives = 296/611 (48%), Gaps = 66/611 (10%)
Query: 628 NEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHF---GSHRYQIL 684
++++ +LI LL I GAVL+FLPG++ I ++ + + +HRYQ+
Sbjct: 600 DDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVF 659
Query: 685 PLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNN 744
LHS + +Q+KV P GV K+ILSTNIAETSIT+NDVV+VIDS K K K F A N
Sbjct: 660 MLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNF 719
Query: 745 MTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIALS 804
+T VW SK + QRKGRAGR RPG CF L SR RF+ + TPE+ R PL E+ L
Sbjct: 720 VTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLH 779
Query: 805 IKLLRLGG--IGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEP 862
KLL I FL KA EPPP V A L+ +DA+D ++LT LG LA LP+EP
Sbjct: 780 TKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEP 839
Query: 863 RFGKMMIMGCIFYVGDAICTIAAATCFPEPFI-----NEGKRLGYIHRNFAGNRFSDHVA 917
GKM++ + D I TIA + +PF+ ++ + + F FSDH+A
Sbjct: 840 HLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMA 899
Query: 918 LLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPE---DCL 974
LL FQAW AR G E FCE L+ AT+ + + QL L SGF
Sbjct: 900 LLRAFQAWQKARSDGWER--AFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGD 957
Query: 975 LTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILT-TEGRNALIHKSSVNC---- 1029
+ V TN+ N VV + L G+YPN+ + + +LT + + H +SV
Sbjct: 958 IRDVNTNS---ENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQY 1014
Query: 1030 ----PFSSQD---MKYPSPFFVFGEKIRT-RAISAKGMTLVTPLQLLLF------ASKKV 1075
P + Q P+ + ++ E R R + + + VTP+ +L+F AS +
Sbjct: 1015 KKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNAL 1074
Query: 1076 Q--------------SDGQI----------VLVDDWIKLQISHEAAACITGLRAAMEALV 1111
Q SD ++ + +D+W+ + EAA+ + LR +L
Sbjct: 1075 QEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLF 1134
Query: 1112 VEVTKQPA-IISQLDPVNERMLNMIRQISRPSAAGINLMIGSTRYGDGPRPPKMARYDNG 1170
+ + P+ SQ+D R + + S AG+ G G PRP
Sbjct: 1135 LRRMRAPSKPWSQVDEATIRAIIAVLSTEEQS-AGLQQPSG---IGQRPRPMSSEELPLA 1190
Query: 1171 SGYRRGGSSYS 1181
S +R S S
Sbjct: 1191 SSWRSNNSRKS 1201
Score = 197 bits (501), Expect = 5e-50
Identities = 103/218 (47%), Positives = 147/218 (67%), Gaps = 6/218 (2%)
Query: 385 RELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIVVTQ 444
R+ LPV + + EI++ I +N VV+I G TG GKTTQ+PQF+LDD +N C I TQ
Sbjct: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKN--GIPCRIFCTQ 247
Query: 445 PRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAG--- 501
PRR++A++VAERVA ER E G++ GY +R ES + P + FCT GVLLR L AG
Sbjct: 248 PRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVS-PKTLLTFCTNGVLLRTLMAGDST 306
Query: 502 IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPII 561
+ ++HVIVDE+HERD +DFLL LRD++Q +P ++++L SA +D ++F YF +CP+I
Sbjct: 307 LSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVI 366
Query: 562 EVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDD 599
+ GR + V+E FLED ++ T + K KK+K +
Sbjct: 367 YIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQE 404
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapiens]
Length = 703
Score = 258 bits (659), Expect = 3e-68
Identities = 217/775 (28%), Positives = 356/775 (45%), Gaps = 98/775 (12%)
Query: 335 PQSNWNPWTSSNIDEGPLAFATPEQISMDLKNELMYQLEQDHDLQAILQERELLPVKKFE 394
P W P T EGP + E+ S+ +N + + +I Q+R+ LPV K
Sbjct: 7 PVKFWRPGT-----EGPGVSISEERQSL-AENSGTTVVYNPYAALSIEQQRQKLPVFKLR 60
Query: 395 SEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIV-VTQPRRISAVSV 453
+ IL I V+I G TGCGK+TQ+PQ++ + AE +V VTQPRR++AV+V
Sbjct: 61 NHILYLIENYQTVVIVGETGCGKSTQIPQYLAEA----GWTAEGRVVGVTQPRRVAAVTV 116
Query: 454 AERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAG--IRGISHVIVD 511
A RVA ERG G GY +RF+ + I F T G+L+R++ + S +++D
Sbjct: 117 AGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLD 176
Query: 512 EIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFN----------CPII 561
E HER + TD + +L+ + + ++R+++ SAT+D F ++F C I+
Sbjct: 177 EAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVIL 236
Query: 562 EVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGPETR 621
V GRT+PV ++L+ + ++ + K +G D A + G E
Sbjct: 237 TVEGRTFPVDIFYLQSPVP--DYIKSTVETVVKIHQTEGDGDVLA---FLTGQE------ 285
Query: 622 LSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGSHRY 681
E ET ++ L++ L G M++HL
Sbjct: 286 -------EVET---VVSMLIEQARALARTG--------------MKRHL----------- 310
Query: 682 QILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTA 741
++LP+++ +P EQ KVF+ V V KVI++TN+AETSITI+ +VYVID K++ +
Sbjct: 311 RVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNP 370
Query: 742 HNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEI 801
+ V S+ + QR GR GR R G C+ L + F++L PEM R+ L +
Sbjct: 371 RTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPV 430
Query: 802 ALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELT-PLGRILAKLPI 860
L +K L + + +F + PPP ++++A L L LD + LT PLG +A+ P+
Sbjct: 431 ILQLKALGIDNVLRF--HFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPL 488
Query: 861 EPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFI---NEGKRLGYIHRNFAGNRFSDHVA 917
P F KM++ F I +IAA F+ N+ +HR FA DH+
Sbjct: 489 NPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVEE-GDHLT 547
Query: 918 LLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQ 977
+L++++A+ + ++C+ LN L + QLK++L+ P
Sbjct: 548 MLNIYEAFIK-----HNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVP------- 595
Query: 978 VFTNTGPDNNLDVVISLLAFGVYPNVC-YHKEKRKILTTEGRNALIHKSSVNCPFSSQDM 1036
+ + D+V+ + G + N +H + IH +SV
Sbjct: 596 ---RKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASV------LYA 646
Query: 1037 KYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVLVDDWIKLQ 1091
+ P + ++ E I+T + +T + LL A Q + L K+Q
Sbjct: 647 EKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQ 701
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 256 bits (653), Expect = 1e-67
Identities = 179/593 (30%), Positives = 291/593 (49%), Gaps = 71/593 (11%)
Query: 380 AILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECN 439
+IL++RE LP+ K + ++++A+ N ++I+ G TG GKTTQ+ Q++ + + C
Sbjct: 557 SILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGC- 615
Query: 440 IVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRK-- 497
TQPRR++A+SVA+RV+ E G G+ GY++RFE P I + T G+LLR+
Sbjct: 616 ---TQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTS-PETVIKYMTDGMLLRECL 671
Query: 498 LEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFN 557
++ + + +++DE HER I+TD L +L+ VQ ++++++ SAT+D F +YF+
Sbjct: 672 IDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYE 731
Query: 558 CPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYG 617
PI + GRTYPV+ + ++ E D + +LI
Sbjct: 732 APIFTIPGRTYPVEILYTKE-----------------------PETDYLDASLIT----- 763
Query: 618 PETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHL-EMNPHF 676
+ I PG +LVFL G I T + L E
Sbjct: 764 -----------------------VMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSL 800
Query: 677 GSHRYQ--ILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQ 734
G + ILP++S +P E Q ++FDP P G KV+++TNIAETS+TI+ + YV+D
Sbjct: 801 GPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFV 860
Query: 735 KVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHL-CSRARFERLETHMTPEM 793
K K++ + + S+ +QR GRAGR PG C+ L RA + + T PE+
Sbjct: 861 KQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEI 920
Query: 794 FRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGR 853
RT L LS+K + + + F ++ PP++ +I A L L ALD LT LGR
Sbjct: 921 QRTNLASTVLSLKAMGINDLLSF--DFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGR 978
Query: 854 ILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRLGYIHRNFA--GNR 911
+A+ P+EP KM+IM + + TI + F + + A
Sbjct: 979 RMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQT 1038
Query: 912 FSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEIL 964
DH+ LL+V+ +W + + +C + +LR + + Q+ I+
Sbjct: 1039 EGDHLTLLAVYNSWKNNKFSNP-----WCYENFIQARSLRRAQDIRKQMLGIM 1086
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 251 bits (640), Expect = 4e-66
Identities = 184/605 (30%), Positives = 295/605 (48%), Gaps = 78/605 (12%)
Query: 371 QLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFI 430
Q +Q +QA+ R LPV F E+L AI+ + V+II G TG GKTTQ+PQ++ ++
Sbjct: 385 QAQQKESIQAV---RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGY 441
Query: 431 QNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCT 490
N I TQPRR++A+SVA RVA E G + G GYS+RFE + + T
Sbjct: 442 TN---KGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSE-RTVLRYMT 497
Query: 491 VGVLLRKL--EAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDT 548
G+LLR+ E + S V+VDE HER ++TD L +++DV + PE+++++ SAT+DT
Sbjct: 498 DGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDT 557
Query: 549 SMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANC 608
+ F +F + P+ + GR +PV ++ + P D
Sbjct: 558 ARFSTFFDDAPVFRIPGRRFPVDIFYTK---------APEAD------------------ 590
Query: 609 NLICGDEYGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQK 668
Y +S+ Q++ + P +++ VFL G I +
Sbjct: 591 -------YLEACVVSVLQIHVTQPPGDIL-----------------VFLTGQEEIEAACE 626
Query: 669 HLEMNP--HFGSHRYQILPL--HSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITIND 724
L+ +P GS ++L L ++ +P + Q ++F P P G KV+++TNIAETS TI
Sbjct: 627 MLQ-DPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEG 685
Query: 725 VVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFE- 783
++YV+D K K + M + SK + QR GRAGRV G CF L + ++
Sbjct: 686 IIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQH 745
Query: 784 RLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALD 843
LE PE+ RT L + L +K L + + F ++PPP + ++ L L AL+
Sbjct: 746 ELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHF--DFLDPPPYETLLLTLEQLYALGALN 803
Query: 844 ANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRLGYI 903
ELT GR +A+LP++P KM++ + + I T+AA K +
Sbjct: 804 HLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKD-KVV 862
Query: 904 HRNFAGNRF----SDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQ 959
H + A F DH+ LL+V+ W ++ + +C + ++R + + Q
Sbjct: 863 HADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQ-----WCCENFVQFRSMRRARDVREQ 917
Query: 960 LKEIL 964
L+ +L
Sbjct: 918 LEGLL 922
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
sapiens]
Length = 795
Score = 251 bits (640), Expect = 4e-66
Identities = 174/607 (28%), Positives = 307/607 (50%), Gaps = 79/607 (13%)
Query: 381 ILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNI 440
IL++R LPV +++ + + ++ ++ G TG GKTTQ+PQ+ ++ ++++ + +
Sbjct: 130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVE-YMRSLPGPKRGV 188
Query: 441 VVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL-- 498
TQPRR++A+SVA+RVA E G+ GYS+RFE + + T G+LLR+
Sbjct: 189 ACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDC-SSAKTILKYMTDGMLLREAMN 247
Query: 499 EAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNC 558
+ + +I+DE HER + TD L+ VL++VV+ ++++++MSAT+D F YF NC
Sbjct: 248 DPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNC 307
Query: 559 PIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGP 618
P++ + GRT+PV+ ++ + P +D E
Sbjct: 308 PLLTIPGRTHPVEIFYTPE---------PERDYL----------------------EAAI 336
Query: 619 ETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHL-----EMN 673
T + + E+E G +L+FL G I K + ++
Sbjct: 337 RTVIQIHMCEEEE-------------------GDLLLFLTGQEEIDEACKRIKREVDDLG 377
Query: 674 PHFGSHRYQILPLHSQIPREEQRKVFDPVP-------VGVTKVILSTNIAETSITINDVV 726
P G +I+PL+S +P ++Q+++F+P P +G KV++STNIAETS+TI+ VV
Sbjct: 378 PEVGD--IKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIG-RKVVVSTNIAETSLTIDGVV 434
Query: 727 YVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFE-RL 785
+VID K K++ + + SK + +QR GRAGR RPG CF L + ++ +
Sbjct: 435 FVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEM 494
Query: 786 ETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDAN 845
+ + PE+ R+ L + L +K L + + F ++PP + ++ A L L AL+ +
Sbjct: 495 QDNTYPEILRSNLGSVVLQLKKLGIDDLVHF--DFMDPPAPETLMRALELLNYLAALNDD 552
Query: 846 DELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFI--NEGKRLGYI 903
+LT LG ++A+ P++P+ KM+I C + + + +I A P+ F+ E K+
Sbjct: 553 GDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADE 612
Query: 904 HRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEI 963
+ + DH+ LL+V+ A+ +++C +N +L + QL I
Sbjct: 613 AKMRFAHIDGDHLTLLNVYHAFKQ-----NHESVQWCYDNFINYRSLMSADNVRQQLSRI 667
Query: 964 LINSGFP 970
+ P
Sbjct: 668 MDRFNLP 674
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapiens]
Length = 707
Score = 243 bits (621), Expect = 6e-64
Identities = 187/668 (27%), Positives = 315/668 (47%), Gaps = 92/668 (13%)
Query: 379 QAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAEC 438
+A+ +R LP+ + ++L + ++ G TG GKTTQ+PQ++ + I
Sbjct: 65 EAVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGI--- 121
Query: 439 NIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL 498
I VTQPRR++A+S+A RV+ E+ E GK GY+VRF+ + I F T G+LLR+
Sbjct: 122 -IAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSED-TRIKFLTDGMLLREA 179
Query: 499 --EAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEV-----RIVLMSATIDTSMF 551
++ +R S VI+DE HER I+TD L V++ + E+ ++++MSAT+D +F
Sbjct: 180 ISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLF 239
Query: 552 CEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLI 611
+YF P++ + GR +P+Q ++ + P D
Sbjct: 240 SQYFNGAPVLYLEGRQHPIQVFYTKQ---------PQND--------------------- 269
Query: 612 CGDEYGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHL- 670
Y +S+ Q++++ + +LVFL G I M K
Sbjct: 270 ----YLHAALVSVFQIHQEAPSSQ----------------DILVFLTGQEEIEAMSKTCR 309
Query: 671 EMNPHF--GSHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYV 728
++ H G +LPL++ +P +Q +VF P G KVI+STNIAETSITI + YV
Sbjct: 310 DIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYV 369
Query: 729 IDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETH 788
+D+ K K + + + A SKT QR GRAGR G C+ L + FE+ +
Sbjct: 370 VDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFEKFDKM 429
Query: 789 MTPEMFRTPLHEIALSIKLLRLGGI--GQFLAKAIEPPPLDAVIEAEHTLRELDALDAND 846
PE+ R L + L + +++ + F++K P + A I L L+ D
Sbjct: 430 TVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKP-SPDHIQAAIAQLDLLGALEHKDDQL 488
Query: 847 ELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKR---LGYI 903
LTP+GR +A P+EP+F K ++M F+ + I TI + N R + +
Sbjct: 489 TLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSVDSVLHNPPSRREEVQGV 548
Query: 904 HRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEI 963
+ F + DH+ LL++++ + + +GG + +C+ +N + + E + QL++I
Sbjct: 549 RKKFISSE-GDHMTLLNIYRTFKN--LGGNK---DWCKENFVNSKNMTLVAEVRAQLRDI 602
Query: 964 LINSGFP-----------EDCLLTQVFTNTG---PDNNLDVVISLLAFGVYP-NVCYHKE 1008
+ P CL +F +T PD + ++P +V +H +
Sbjct: 603 CLKMSMPIASSRGDVESVRRCLAHSLFMSTAELQPDGTYATTDTHQPVAIHPSSVLFHCK 662
Query: 1009 KRKILTTE 1016
++ TE
Sbjct: 663 PACVVYTE 670
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens]
Length = 779
Score = 228 bits (581), Expect = 3e-59
Identities = 194/708 (27%), Positives = 324/708 (45%), Gaps = 103/708 (14%)
Query: 389 PVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILD-DFIQNDRAAECNIVVTQPRR 447
P++K +I++A+ NS +I+ G TG GKTTQ+P+++ + F Q+ I VTQPR+
Sbjct: 54 PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM-----IGVTQPRK 108
Query: 448 ISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL--EAGIRGI 505
++A+SVA+RVA E G GY VRF+ + A I + T G LL+ + + +
Sbjct: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETA-IKYMTDGCLLKHILGDPNLTKF 167
Query: 506 SHVIVDEIHERDINTDFLLVVLRDVVQAYP-----EVRIVLMSATIDTSMFCEYFFNCPI 560
S +I+DE HER + TD L +L+ + Q +++V+MSAT++ + +F NCPI
Sbjct: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227
Query: 561 IEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGPET 620
++ GR YPV+E F CNLI GP
Sbjct: 228 FDIPGRLYPVREKF---------------------------------CNLI-----GPRD 249
Query: 621 RLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGW-------NLIYTMQKHLEMN 673
R E + I + I + G +LVFL G L++ M + ++ +
Sbjct: 250 R-------ENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302
Query: 674 PHFGSHRYQ---ILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVID 730
ILP + + ++QR++F P P G+ K ++STNI+ TS+TI+ + YV+D
Sbjct: 303 YDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362
Query: 731 SCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFER-LETHM 789
K + V SK+ QR GRAGR G CF + S+ + + + H+
Sbjct: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422
Query: 790 TPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELT 849
PE+ RT L + L++K L + + +F ++PP ++EA L + DA+D + +T
Sbjct: 423 IPEIKRTSLTSVVLTLKCLAIHDVIRF--PYLDPPNERLILEALKQLYQCDAIDRSGHVT 480
Query: 850 PLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINE-----GKRLGYIH 904
LG + + P+ P +I D + IAA FI K H
Sbjct: 481 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 540
Query: 905 RNFAGNR--FSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKE 962
R A F+D L +F + + G A +C+ ++ L + + QL+E
Sbjct: 541 RELAAKAGGFNDFATLAVIF---EQCKSSGAPAS--WCQKHWIHWRCLFSAFRVEAQLRE 595
Query: 963 IL----INSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGR 1018
++ S FP++ T GP + +V+ L G + NV R T +GR
Sbjct: 596 LIRKLKQQSDFPKE-------TFEGPKH--EVLRRCLCAGYFKNVARRSVGRTFCTVDGR 646
Query: 1019 NALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQ 1066
+ +H ++ + + + + +F E + T + A+ +V P++
Sbjct: 647 GSPVH---IHPSSALHEQETKLEWIIFHEVLVTTKVYAR---IVCPIR 688
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 185 bits (469), Expect = 3e-46
Identities = 136/448 (30%), Positives = 220/448 (49%), Gaps = 70/448 (15%)
Query: 389 PVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILD-DFIQNDRAAECNIVVTQPRR 447
P++K +I++A+ NS +I+ G TG GKTTQ+P+++ + F Q+ I VTQPR+
Sbjct: 54 PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM-----IGVTQPRK 108
Query: 448 ISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL--EAGIRGI 505
++A+SVA+RVA E G GY VRF+ + A I + T G LL+ + + +
Sbjct: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETA-IKYMTDGCLLKHILGDPNLTKF 167
Query: 506 SHVIVDEIHERDINTDFLLVVLRDVVQAYP-----EVRIVLMSATIDTSMFCEYFFNCPI 560
S +I+DE HER + TD L +L+ + Q +++V+MSAT++ + +F NCPI
Sbjct: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227
Query: 561 IEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGPET 620
++ GR YPV+E F CNLI GP
Sbjct: 228 FDIPGRLYPVREKF---------------------------------CNLI-----GPRD 249
Query: 621 RLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPG-------WNLIYTMQKHLEMN 673
R E + I + I + G +LVFL G L++ M + ++ +
Sbjct: 250 R-------ENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302
Query: 674 PHFGS---HRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVID 730
ILP + + ++QR++F P P G+ K ++STNI+ TS+TI+ + YV+D
Sbjct: 303 YDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362
Query: 731 SCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFER-LETHM 789
K + V SK+ QR GRAGR G CF + S+ + + + H+
Sbjct: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422
Query: 790 TPEMFRTPLHEIALSIKLLRLGGIGQFL 817
PE+ RT L + L++K L + + +++
Sbjct: 423 IPEIKRTSLTSVVLTLKCLAIHDVIRYV 450
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 157 bits (397), Expect = 6e-38
Identities = 154/604 (25%), Positives = 268/604 (44%), Gaps = 83/604 (13%)
Query: 381 ILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNI 440
+L+ERE LP+ K + +E + QN +VI+ G CGK+ QVPQ+ + + + +
Sbjct: 55 LLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAE-YCLSIHYQHGGV 113
Query: 441 VVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEA 500
+ TQ + + V +A RVA E G GY + FE+ + +CT +L R++ +
Sbjct: 114 ICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTN-ETILRYCTDDMLQREMMS 172
Query: 501 G--IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNC 558
+ +I+D+IHER I TD LL +L+DV+ A PE+++++ S+ S Y+ N
Sbjct: 173 NPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNV 232
Query: 559 PIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGP 618
P+IEV + +PV+ +L + +KD
Sbjct: 233 PVIEVKNK-HPVEVVYLSEA--------------QKDS---------------------- 255
Query: 619 ETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPG----WNLIYTMQKHLEMNP 674
FE I L+ I G ++VFL + T+ + +NP
Sbjct: 256 ---------------FESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQGSNLNP 300
Query: 675 HFGSHRYQILPLHSQIPREEQRKVFDPV-------PVGVTKVILSTNIAETSITINDVVY 727
G ++PL+ +E+ +F P+ V +V+L+T+ E I N V +
Sbjct: 301 DLG--ELVVVPLYP----KEKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSNSVRF 354
Query: 728 VIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLET 787
VID ++ K++ + S++ E RK G G F L + + T
Sbjct: 355 VIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMT 414
Query: 788 HMTP-EMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDAND 846
+ P EM L + L +K + + G+G + P +++++A L L ALD +
Sbjct: 415 PLKPAEMQEANLTSMVLFMKRIDIAGLGH--CDFMNRPAPESLMQALEDLDYLAALDNDG 472
Query: 847 ELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPF--INEGKRLGYI- 903
L+ G I+++ P++P+ K ++ C F D + TIAA P F + G +
Sbjct: 473 NLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEEAALT 532
Query: 904 -HRNFAGNRFSDHVALLSVFQAWDDARM--GGEEAEIRFCEHKRLNMATLRMTWEAKVQL 960
+ F + DH L+S+++A+ D + E ++C LN + LRM + +L
Sbjct: 533 CWKTFL-HPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRAEL 591
Query: 961 KEIL 964
EI+
Sbjct: 592 LEII 595
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 157 bits (397), Expect = 6e-38
Identities = 111/347 (31%), Positives = 174/347 (50%), Gaps = 22/347 (6%)
Query: 631 ETPFE-LIEALLKY---IETLNVPGAVLVFLPGWNLIYTMQ----KHLEMNPHFGSHRYQ 682
+TP E +EA +K + PG +L+F+PG I +HLE + +
Sbjct: 717 KTPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELEN--APALA 774
Query: 683 ILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAH 742
+LP++SQ+P + Q K+F P GV K I++TNIAETS+T++ +++VIDS K+K+F
Sbjct: 775 VLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPR 834
Query: 743 NNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFE-RLETHMTPEMFRTPLHEI 801
M S+ N QR GRAGR PG CF L +++ ++ L T PE+ RT L +
Sbjct: 835 IGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANV 894
Query: 802 ALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIE 861
L +K L + + QF ++PPP D ++ + + L L ALD LT GR++ + P++
Sbjct: 895 VLLLKSLGVQDLLQF--HFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLD 952
Query: 862 PRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKR---LGYIHRNFAGNRFSDHVAL 918
P KM+I+ C I I + P F R I FA SDH+
Sbjct: 953 PALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPE-SDHLTY 1011
Query: 919 LSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILI 965
L+V+ W + +C ++ +R E + QLK+I++
Sbjct: 1012 LNVYLQWKN-----NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMV 1053
Score = 145 bits (366), Expect = 2e-34
Identities = 85/231 (36%), Positives = 138/231 (59%), Gaps = 12/231 (5%)
Query: 348 DEGPLAFATPEQIS--MDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNS 405
++G + + T ++ + M K+E + + ++IL++R+ LP+ + E+L I NS
Sbjct: 493 EDGKVDYRTEQKFADHMKRKSEASSEFAKK---KSILEQRQYLPIFAVQQELLTIIRDNS 549
Query: 406 VVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEP 465
+VI+ G TG GKTTQ+ Q++ +D + C TQPRR++A+SVA+RV+ E G
Sbjct: 550 IVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGC----TQPRRVAAMSVAKRVSEEMGGNL 605
Query: 466 GKSCGYSVRFESILPRPHASIMFCTVGVLLRKL--EAGIRGISHVIVDEIHERDINTDFL 523
G+ GY++RFE + I + T G+LLR+ EA + S +I+DE HER +NTD L
Sbjct: 606 GEEVGYAIRFEDCTSE-NTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVL 664
Query: 524 LVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYF 574
+LR+VV ++++++ SAT+D F +F N PI + GRT+PV F
Sbjct: 665 FGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILF 715
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
Length = 1157
Score = 133 bits (335), Expect = 9e-31
Identities = 111/425 (26%), Positives = 187/425 (44%), Gaps = 60/425 (14%)
Query: 683 ILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAH 742
+LPL+S + E+Q +VF P P G +++TN+AETS+TI + YV+D K K + +
Sbjct: 590 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRV 649
Query: 743 NNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIA 802
++++ W S+ + +QR GRAGR PG C+ L S A F E PE+ R P+ ++
Sbjct: 650 TGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLI 709
Query: 803 LSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDE--------------- 847
L +K L + + F PP ++A++ AE L L AL +
Sbjct: 710 LQMKALNVEKVINFPFPT--PPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCP 767
Query: 848 LTPLGRILAKLPIEPRFGKMMIM----GCIFYVGDAICTIAAATCFPE---PFINEGK-- 898
+T LGR +A P+ PR+ KM+ + GC+ Y + ++ F E P ++ +
Sbjct: 768 ITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELT 827
Query: 899 -------RLGYIHRNFAGN----RFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNM 947
R+ + R +AG + D + LL A + A +FCE L
Sbjct: 828 RLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYA-----SCTPQFCEANGLRY 882
Query: 948 ATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHK 1007
+ + QL +N+ PE L ++ + + ++ G+ ++
Sbjct: 883 KAMMEIRRLRGQL-TTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRV 941
Query: 1008 EKRKILTTEGRNA----------LIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAK 1057
+ ++L + RNA IH SSV K F V+ E + T + K
Sbjct: 942 QSEEMLEDKWRNAYKTPLLDDPVFIHPSSVL-------FKELPEFVVYQEIVETTKMYMK 994
Query: 1058 GMTLV 1062
G++ V
Sbjct: 995 GVSSV 999
Score = 104 bits (259), Expect = 6e-22
Identities = 78/266 (29%), Positives = 138/266 (51%), Gaps = 18/266 (6%)
Query: 319 EPSQRQNQVGVVPWSPPQSNWNPWTSSNIDEGPLAFATPEQISMDLKNELMYQLEQDHDL 378
EP++ V P P + + + + P A P K + + + ++
Sbjct: 186 EPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVNRSPEM 245
Query: 379 QAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAEC 438
Q +ER LP+ E I+EA++++ +VI+ G TG GKTTQVPQF+ + ++ +
Sbjct: 246 Q---EERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSE---DS 299
Query: 439 NIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL 498
I VT+PRR++AV++++RVA E + Y +R+E + I F T GVLL+++
Sbjct: 300 IIGVTEPRRVAAVAMSQRVAKEMNLSQ-RVVSYQIRYEGNVTE-ETRIKFMTDGVLLKEI 357
Query: 499 EAGIRGISH--VIVDEIHERDINTDFLLVVLRDVVQAYPE----VRIVLMSATIDTSMFC 552
+ + + VI+DE HER + TD L+ +L +V + +++++MSAT+ F
Sbjct: 358 QKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFT 417
Query: 553 E----YFFNCPIIEVYGRTYPVQEYF 574
+ + P+I+V R +PV +F
Sbjct: 418 QNPRLFAKPPPVIKVESRQFPVTVHF 443
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 116 bits (291), Expect = 1e-25
Identities = 149/600 (24%), Positives = 257/600 (42%), Gaps = 83/600 (13%)
Query: 381 ILQERELLPVKKFESEILEAISQN--SVVIIRGATGCGKTTQVPQFILDDFIQNDRAAEC 438
+L++R+ LP+ LE + N VV++ G G GK+TQ+PQ+ + F +
Sbjct: 38 LLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAE-FALARGFQKG 96
Query: 439 NIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL 498
+ VTQP ++A S+A RVA E G GYS+ E P+ + FC +LL+++
Sbjct: 97 QVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQED-CTGPNTLLRFCWDRLLLQEV 155
Query: 499 EAGIRGISH---VIVDEIHERDINTDFLLVVLRDV-VQAYP-EVRIVLMSATIDTSMFCE 553
A RG +++DE ER + +D L +L+D ++ P ++R+V+++
Sbjct: 156 -ASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRA 214
Query: 554 YFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICG 613
++ N PI+ + D I PP + +A C +
Sbjct: 215 FWGNPPIVHIPREPGERPSPIYWDTI------PPDR--------------VEAACQAVL- 253
Query: 614 DEYGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMN 673
+L KE P G VLVFLP I + L
Sbjct: 254 ------------ELCRKELP-----------------GDVLVFLPSEEEISLCCESLSRE 284
Query: 674 PH---FGSHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVID 730
++LPLH R Q D + KV+++ +A+ S ++ + +VID
Sbjct: 285 VESLLLQGLPPRVLPLHPDCGRAVQAVYED---MDARKVVVTHWLADFSFSLPSIQHVID 341
Query: 731 SCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMT 790
S + ++ SK E R+ RA PG C L ++ F LE
Sbjct: 342 SGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFPPGSCLCLYPKS-FLELEAPPL 400
Query: 791 PE--MFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDEL 848
P+ + L + L +K ++ G+ ++ P +A+++A L L ALD + +L
Sbjct: 401 PQPRVCEENLSSLVLLLKRRQIAEPGE--CHFLDQPAPEALMQALEDLDYLAALDDDGDL 458
Query: 849 TPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIA----AATCFPEPFINEGKRLGYIH 904
+ LG IL++ P+ P K ++ C F D + T+A AA F P ++ +
Sbjct: 459 SDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPLSAEEA---AL 515
Query: 905 RNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEIL 964
R + DH +L+ V++A+ + G +EA +C+ + LN A L + + +L E++
Sbjct: 516 RRALEHTDGDHSSLIQVYEAF--IQSGADEA---WCQARGLNWAALCQAHKLRGELLELM 570
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 95.1 bits (235), Expect = 4e-19
Identities = 53/109 (48%), Positives = 59/109 (54%), Gaps = 4/109 (3%)
Query: 1166 RYDNGSGYRRGGSSYSGGGYGGGYSSGGYG--SGGYGGSANSFRAGYGAG--VGGGYRGV 1221
R +G Y RG SGG YGGG S GGYG SG GGS S+ G G+G GGGY G
Sbjct: 478 RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGG 537
Query: 1222 SRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGGY 1270
S GG G SGG + G SGG G G GG G YG G +G GG +
Sbjct: 538 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSH 586
Score = 92.4 bits (228), Expect = 2e-18
Identities = 74/203 (36%), Positives = 98/203 (48%), Gaps = 20/203 (9%)
Query: 1079 GQIVLVDDWIKLQISHEAAACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIR-- 1136
GQ+ ++ + QIS+ A IT +R +E E + +I +L+ E N++
Sbjct: 407 GQLQMIQE----QISNLEAQ-ITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGG 461
Query: 1137 QISRPSAAGINLMIGSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGS 1196
Q S+ + +G R G G + +R +G Y GGS GGGYGGG S G
Sbjct: 462 QEDFESSGAGKIGLGG-RGGSGGSYGRGSRGGSGGSYGGGGS---GGGYGGGSGSRGGSG 517
Query: 1197 GGYGGSANS---FRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGG------F 1247
G YGG + S GYG G GGG+ G S GG G SGG+Y G SG GSGG
Sbjct: 518 GSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSG 577
Query: 1248 QRGGGRGAYGTGYFGQGRGGGGY 1270
RGG G++G G G GG Y
Sbjct: 578 SRGGSGGSHGGGSGFGGESGGSY 600
Score = 81.6 bits (200), Expect = 4e-15
Identities = 53/110 (48%), Positives = 56/110 (50%), Gaps = 11/110 (10%)
Query: 1167 YDNGSGYRRG-GSSYSGG-GYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRG 1224
Y GSG R G G SY GG G GGG S GGYG G GG + G+ G GG Y G S
Sbjct: 506 YGGGSGSRGGSGGSYGGGSGSGGG-SGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGS 564
Query: 1225 GFRGNSGGDYRGPSGGYRGSGGFQRGG------GRGAYGTGYFGQGRGGG 1268
G G SGG Y G SG GSGG GG G+YG G G GGG
Sbjct: 565 G--GGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGG 612
Score = 74.7 bits (182), Expect = 5e-13
Identities = 50/112 (44%), Positives = 58/112 (51%), Gaps = 11/112 (9%)
Query: 1165 ARYDNGSGYRRGGSSYSGGGYGGGYSS----GGYGSGGY---GGSANSFRAGYGAGVGGG 1217
+R+ + G GG S GYGGG S GG GS GY GGS F A + +GGG
Sbjct: 33 SRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSA---SSLGGG 89
Query: 1218 YRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
+ G SRG F G SGG Y G G GG GG G YG+G+ G G GGG
Sbjct: 90 FGGGSRG-FGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGG 140
Score = 72.4 bits (176), Expect = 3e-12
Identities = 51/105 (48%), Positives = 59/105 (56%), Gaps = 8/105 (7%)
Query: 1166 RYDNGSGYRRGGSSYSGGGYGG--GYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSR 1223
R+ + SGY G S G G GG GYS GG GSGG G SA+S G+G G G+ G S
Sbjct: 46 RFSSSSGYGGGSSRVCGRGGGGSFGYSYGG-GSGG-GFSASSLGGGFGGG-SRGFGGASG 102
Query: 1224 GGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGG 1268
GG+ +S G + G GG G GGF G G G G G FG G GGG
Sbjct: 103 GGY--SSSGGFGGGFGGGSG-GGFGGGYGSGFGGFGGFGGGAGGG 144
Score = 67.0 bits (162), Expect = 1e-10
Identities = 44/112 (39%), Positives = 49/112 (43%), Gaps = 13/112 (11%)
Query: 1151 GSTRYGDGPRPPKMARYDNGSGYRRGGSSY------SGGGYGGGYSSGGYGSGGYGGSAN 1204
GS G G Y GSG G S SGG YGGG SGG GGYGG +
Sbjct: 518 GSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSG 577
Query: 1205 SFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAY 1256
S R G G GGG GF G SGG Y G GG+ G G+ ++
Sbjct: 578 S-RGGSGGSHGGG------SGFGGESGGSYGGGEEASGSGGGYGGGSGKSSH 622
Score = 60.5 bits (145), Expect = 1e-08
Identities = 50/117 (42%), Positives = 54/117 (46%), Gaps = 25/117 (21%)
Query: 1174 RRGGSSY---SGGGYGGGYSSGGY----------GSGGYGGSANSFRAGYGAGV------ 1214
R+ SSY SGGG GGG SGG GG GG S +GYG G
Sbjct: 4 RQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGR 63
Query: 1215 -GGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGGY 1270
GGG G S GG G+ GG GG G GG RG G GA G GY G GGG+
Sbjct: 64 GGGGSFGYSYGG--GSGGGFSASSLGG--GFGGGSRGFG-GASGGGYSSSGGFGGGF 115
Score = 47.8 bits (112), Expect = 7e-05
Identities = 26/55 (47%), Positives = 31/55 (56%), Gaps = 5/55 (9%)
Query: 1170 GSGYRRGGSSYSGGGYGGGY---SSGGYGSGGYGGSANSFRAGYGAGVGGGYRGV 1221
G G GG S GG+GGG+ S GG+G GGYG F G+G G GGG G+
Sbjct: 96 GFGGASGGGYSSSGGFGGGFGGGSGGGFG-GGYGSGFGGF-GGFGGGAGGGDGGI 148
Score = 38.5 bits (88), Expect = 0.041
Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 5/47 (10%)
Query: 1167 YDNGSGYRRGGSSYSGGGYGGGYSSG-----GYGSGGYGGSANSFRA 1208
Y + G+ G SGGG+GGGY SG G+G G GG A
Sbjct: 105 YSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTA 151
Score = 33.1 bits (74), Expect = 1.7
Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 7/53 (13%)
Query: 1156 GDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYG---SGGYGGSANS 1205
G G R + GSG+ GG S GG YGGG + G G GG G S++S
Sbjct: 575 GSGSRGGSGGSHGGGSGF--GGES--GGSYGGGEEASGSGGGYGGGSGKSSHS 623
Score = 31.2 bits (69), Expect = 6.6
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 13/76 (17%)
Query: 1202 SANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGP------SGGYRGSGGFQRGGGRGA 1255
S F + Y + GGG GG SGG R SGG G G F G G
Sbjct: 2 SCRQFSSSYLSRSGGG------GGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGG 55
Query: 1256 YGTGYFGQGRGGG-GY 1270
+ G+G GG GY
Sbjct: 56 GSSRVCGRGGGGSFGY 71
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 89.0 bits (219), Expect = 3e-17
Identities = 53/119 (44%), Positives = 56/119 (47%), Gaps = 17/119 (14%)
Query: 1167 YDNGSGYR-RGGSSYSGGGYGGGYSSGGYG--------------SGGYGGSANSFRAGYG 1211
Y GYR RGG GGYGG S GGYG GGYGG + GYG
Sbjct: 396 YGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYG 453
Query: 1212 AGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGGY 1270
GGGY G GG+ G+ GG Y G GGY G G GG RG YG G G GGY
Sbjct: 454 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 512
Score = 73.6 bits (179), Expect = 1e-12
Identities = 57/126 (45%), Positives = 62/126 (49%), Gaps = 15/126 (11%)
Query: 1151 GSTRYGDGPRPPKMARY--DNGSGY---RRGGSSYSGGGYGGGYSSGGYGS--GGYGGSA 1203
G R G G + Y D G GY R GG GGYGG GGYG GGYGG
Sbjct: 444 GGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGD-RGGGYGGDRGGYGGD- 501
Query: 1204 NSFRAGYGAGVGGGYRGVSRGGFRGN-SGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFG 1262
R GYG G GGY G RGG+ G+ S G Y G GG G GG + GG G G +G
Sbjct: 502 ---RGGYG-GDRGGYGG-DRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 556
Query: 1263 QGRGGG 1268
RGGG
Sbjct: 557 GDRGGG 562
Score = 66.6 bits (161), Expect = 1e-10
Identities = 45/96 (46%), Positives = 48/96 (50%), Gaps = 16/96 (16%)
Query: 1168 DNGSGYR--RGGSSYSGGGYGGGYSSGGYGS--GGYGGSANSFRAGYGA--GVGGGYRGV 1221
D G GY RGG GGYGG GGYG GGYGG + R GYG G G GY G
Sbjct: 486 DRGGGYGGDRGGYGGDRGGYGGD--RGGYGGDRGGYGGDRS--RGGYGGDRGGGSGYGGD 541
Query: 1222 SRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYG 1257
GG+ G+ G GGY G G GG RG YG
Sbjct: 542 RSGGYGGDRSG------GGYGGDRGGGYGGDRGGYG 571
Score = 61.6 bits (148), Expect = 5e-09
Identities = 45/99 (45%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 1174 RRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAG-VGGGYRG--VSRGGFRGN- 1229
R G + G GYGG G G GG GG R GYG GGGY G S GG+ G+
Sbjct: 385 RPSGGDFRGRGYGG--ERGYRGRGGRGGD----RGGYGGDRSGGGYGGDRSSGGGYSGDR 438
Query: 1230 SGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGG 1268
SGG Y G G G G RGGG G G +G RGGG
Sbjct: 439 SGGGYGGDRSG--GGYGGDRGGGYGGDRGGGYGGDRGGG 475
Score = 58.9 bits (141), Expect = 3e-08
Identities = 40/91 (43%), Positives = 43/91 (47%), Gaps = 18/91 (19%)
Query: 1170 GSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGY----RGVSRGG 1225
G G RGG GGYGG S GGYG GGS GYG GGY G GG
Sbjct: 504 GYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGS------GYGGDRSGGYGGDRSG---GG 554
Query: 1226 FRGNSGGDYRGPSGGYRGSGGFQRGGGRGAY 1256
+ G+ GG Y G GGY G + GGR Y
Sbjct: 555 YGGDRGGGYGGDRGGYGG-----KMGGRNDY 580
Score = 38.9 bits (89), Expect = 0.032
Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 45/107 (42%)
Query: 1206 FRAGYGAGVG----GGYRGVSRGGFRGNSGGDYRG------------------------- 1236
F G G+G G GGYRG RGGF+G G G
Sbjct: 321 FMRGGGSGGGRRGRGGYRG--RGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 378
Query: 1237 -------PSGG-YRGSG-----GFQRGGGRGAYGTGYFGQGRGGGGY 1270
PSGG +RG G G++ GGRG GY G R GGGY
Sbjct: 379 PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGY-GGDRSGGGY 424
Score = 38.1 bits (87), Expect = 0.054
Identities = 39/112 (34%), Positives = 45/112 (40%), Gaps = 10/112 (8%)
Query: 1157 DGPRPPKMARYDNGSGYRRGGSSYSG-GGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVG 1215
D P + YD SGY + SY Y + S Y +S R Y
Sbjct: 103 DQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSY----HSQRENYSHHTQ 158
Query: 1216 GGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGG 1267
R VSR G N G Y G GG RG GG+ + GRG TG G RGG
Sbjct: 159 DDRRDVSRYG-EDNRG--YGGSQGGGRGRGGYDK-DGRGPM-TGSSGGDRGG 205
Score = 35.0 bits (79), Expect = 0.46
Identities = 25/62 (40%), Positives = 30/62 (48%), Gaps = 12/62 (19%)
Query: 1193 GYGSGGYGGSANSFRAGYGAGVG-GGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGG 1251
G + GYGGS G G G GGY RG G+SGGD GG++ GG + G
Sbjct: 168 GEDNRGYGGSQ-------GGGRGRGGYDKDGRGPMTGSSGGD----RGGFKNFGGHRDYG 216
Query: 1252 GR 1253
R
Sbjct: 217 PR 218
Score = 33.1 bits (74), Expect = 1.7
Identities = 36/120 (30%), Positives = 44/120 (36%), Gaps = 20/120 (16%)
Query: 1149 MIGSTRYGD-GPRPPKMARYDN--GSGYRRGGSSYSGGG------YGGGYSSGGYGSGG- 1198
M S YG G + Y N GY + SYSG G YG YS GY S G
Sbjct: 1 MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYS--GYSSYGQ 58
Query: 1199 -----YGGSANSFRAGYGA---GVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRG 1250
YGG N ++ Y G + + G +G Y P G + S Q G
Sbjct: 59 SYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSG 118
Score = 32.7 bits (73), Expect = 2.3
Identities = 22/47 (46%), Positives = 23/47 (48%), Gaps = 9/47 (19%)
Query: 1170 GSGY---RRGG--SSYSGGGYGG----GYSSGGYGSGGYGGSANSFR 1207
GSGY R GG SGGGYGG GY G GG G N +R
Sbjct: 535 GSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYR 581
Score = 31.2 bits (69), Expect = 6.6
Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 9/65 (13%)
Query: 1174 RRGGSSYSGGGYG-GGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGG 1232
RR S Y G GG GG G GGY G G G G RGGF+ G
Sbjct: 161 RRDVSRYGEDNRGYGGSQGGGRGRGGYDKD--------GRGPMTGSSGGDRGGFKNFGGH 212
Query: 1233 DYRGP 1237
GP
Sbjct: 213 RDYGP 217
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 89.0 bits (219), Expect = 3e-17
Identities = 53/119 (44%), Positives = 56/119 (47%), Gaps = 17/119 (14%)
Query: 1167 YDNGSGYR-RGGSSYSGGGYGGGYSSGGYG--------------SGGYGGSANSFRAGYG 1211
Y GYR RGG GGYGG S GGYG GGYGG + GYG
Sbjct: 399 YGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYG 456
Query: 1212 AGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGGY 1270
GGGY G GG+ G+ GG Y G GGY G G GG RG YG G G GGY
Sbjct: 457 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 515
Score = 73.6 bits (179), Expect = 1e-12
Identities = 57/126 (45%), Positives = 62/126 (49%), Gaps = 15/126 (11%)
Query: 1151 GSTRYGDGPRPPKMARY--DNGSGY---RRGGSSYSGGGYGGGYSSGGYGS--GGYGGSA 1203
G R G G + Y D G GY R GG GGYGG GGYG GGYGG
Sbjct: 447 GGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGD-RGGGYGGDRGGYGGD- 504
Query: 1204 NSFRAGYGAGVGGGYRGVSRGGFRGN-SGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFG 1262
R GYG G GGY G RGG+ G+ S G Y G GG G GG + GG G G +G
Sbjct: 505 ---RGGYG-GDRGGYGG-DRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 559
Query: 1263 QGRGGG 1268
RGGG
Sbjct: 560 GDRGGG 565
Score = 66.6 bits (161), Expect = 1e-10
Identities = 45/96 (46%), Positives = 48/96 (50%), Gaps = 16/96 (16%)
Query: 1168 DNGSGYR--RGGSSYSGGGYGGGYSSGGYGS--GGYGGSANSFRAGYGA--GVGGGYRGV 1221
D G GY RGG GGYGG GGYG GGYGG + R GYG G G GY G
Sbjct: 489 DRGGGYGGDRGGYGGDRGGYGGD--RGGYGGDRGGYGGDRS--RGGYGGDRGGGSGYGGD 544
Query: 1222 SRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYG 1257
GG+ G+ G GGY G G GG RG YG
Sbjct: 545 RSGGYGGDRSG------GGYGGDRGGGYGGDRGGYG 574
Score = 61.6 bits (148), Expect = 5e-09
Identities = 45/99 (45%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 1174 RRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAG-VGGGYRG--VSRGGFRGN- 1229
R G + G GYGG G G GG GG R GYG GGGY G S GG+ G+
Sbjct: 388 RPSGGDFRGRGYGG--ERGYRGRGGRGGD----RGGYGGDRSGGGYGGDRSSGGGYSGDR 441
Query: 1230 SGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGG 1268
SGG Y G G G G RGGG G G +G RGGG
Sbjct: 442 SGGGYGGDRSG--GGYGGDRGGGYGGDRGGGYGGDRGGG 478
Score = 58.9 bits (141), Expect = 3e-08
Identities = 40/91 (43%), Positives = 43/91 (47%), Gaps = 18/91 (19%)
Query: 1170 GSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGY----RGVSRGG 1225
G G RGG GGYGG S GGYG GGS GYG GGY G GG
Sbjct: 507 GYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGS------GYGGDRSGGYGGDRSG---GG 557
Query: 1226 FRGNSGGDYRGPSGGYRGSGGFQRGGGRGAY 1256
+ G+ GG Y G GGY G + GGR Y
Sbjct: 558 YGGDRGGGYGGDRGGYGG-----KMGGRNDY 583
Score = 38.9 bits (89), Expect = 0.032
Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 45/107 (42%)
Query: 1206 FRAGYGAGVG----GGYRGVSRGGFRGNSGGDYRG------------------------- 1236
F G G+G G GGYRG RGGF+G G G
Sbjct: 324 FMRGGGSGGGRRGRGGYRG--RGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 381
Query: 1237 -------PSGG-YRGSG-----GFQRGGGRGAYGTGYFGQGRGGGGY 1270
PSGG +RG G G++ GGRG GY G R GGGY
Sbjct: 382 PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGY-GGDRSGGGY 427
Score = 38.1 bits (87), Expect = 0.054
Identities = 39/112 (34%), Positives = 45/112 (40%), Gaps = 10/112 (8%)
Query: 1157 DGPRPPKMARYDNGSGYRRGGSSYSG-GGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVG 1215
D P + YD SGY + SY Y + S Y +S R Y
Sbjct: 106 DQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSY----HSQRENYSHHTQ 161
Query: 1216 GGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGG 1267
R VSR G N G Y G GG RG GG+ + GRG TG G RGG
Sbjct: 162 DDRRDVSRYG-EDNRG--YGGSQGGGRGRGGYDK-DGRGPM-TGSSGGDRGG 208
Score = 35.0 bits (79), Expect = 0.46
Identities = 25/62 (40%), Positives = 30/62 (48%), Gaps = 12/62 (19%)
Query: 1193 GYGSGGYGGSANSFRAGYGAGVG-GGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGG 1251
G + GYGGS G G G GGY RG G+SGGD GG++ GG + G
Sbjct: 171 GEDNRGYGGSQ-------GGGRGRGGYDKDGRGPMTGSSGGD----RGGFKNFGGHRDYG 219
Query: 1252 GR 1253
R
Sbjct: 220 PR 221
Score = 32.7 bits (73), Expect = 2.3
Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 1168 DNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFR 1227
D+GS + GG S YG GS GYG ++ S+ +GYG Y G + G+
Sbjct: 3 DSGSYGQSGGEQQSYSTYGNP------GSQGYGQASQSY-SGYGQTTDSSY-GQNYSGYS 54
Query: 1228 --GNSGGDYRGPSGGY 1241
G S Y GGY
Sbjct: 55 SYGQSQSGYSQSYGGY 70
Score = 32.7 bits (73), Expect = 2.3
Identities = 22/47 (46%), Positives = 23/47 (48%), Gaps = 9/47 (19%)
Query: 1170 GSGY---RRGG--SSYSGGGYGG----GYSSGGYGSGGYGGSANSFR 1207
GSGY R GG SGGGYGG GY G GG G N +R
Sbjct: 538 GSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYR 584
Score = 31.2 bits (69), Expect = 6.6
Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 9/65 (13%)
Query: 1174 RRGGSSYSGGGYG-GGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGG 1232
RR S Y G GG GG G GGY G G G G RGGF+ G
Sbjct: 164 RRDVSRYGEDNRGYGGSQGGGRGRGGYDKD--------GRGPMTGSSGGDRGGFKNFGGH 215
Query: 1233 DYRGP 1237
GP
Sbjct: 216 RDYGP 220
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 85.9 bits (211), Expect = 2e-16
Identities = 56/110 (50%), Positives = 61/110 (55%), Gaps = 19/110 (17%)
Query: 1169 NGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRG 1228
+G G R GGS GGGYGGG S GG GG+GG G+G GGGY G S GG G
Sbjct: 459 SGGGGRGGGSF--GGGYGGGSSGGGSSGGGHGG-------GHGGSSGGGYGGGSSGG--G 507
Query: 1229 NSGGDYRG--PSGGYRGS-----GGFQRGGGRGAYGTGYFGQG-RGGGGY 1270
+SGG Y G SGG+ GS GG GGG G YG G G G GGGY
Sbjct: 508 SSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGY 557
Score = 76.6 bits (187), Expect = 1e-13
Identities = 62/179 (34%), Positives = 77/179 (43%), Gaps = 14/179 (7%)
Query: 1098 ACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISRPSAAGINLMIGSTR--- 1154
A I+ L ++ + E Q QL + R+ N I Q R G G R
Sbjct: 409 AQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEI-QTYRSLLEGEGSSGGGGRGGG 467
Query: 1155 -YGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAG 1213
+G G +G G+ G SGGGYGGG S GG GGYGG ++S G+G
Sbjct: 468 SFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSS--GGHGGS 525
Query: 1214 VGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRG----GGRGAYGTGYFGQGRGGG 1268
GGY G S GG G GG G SGG SGG G GG + +G G+ G
Sbjct: 526 SSGGYGGGSSGGGGGGYGG---GSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581
Score = 73.2 bits (178), Expect = 2e-12
Identities = 46/97 (47%), Positives = 51/97 (52%), Gaps = 11/97 (11%)
Query: 1176 GGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYR 1235
G S GGG GGG GGYG G GG ++ G G GGG+ G S GG+ G S G
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSS------GGGHGGGHGGSSGGGYGGGSSGG-- 506
Query: 1236 GPSGGYRGSGGFQRGGGRGAYGTGYFG--QGRGGGGY 1270
G SGG G GG GG G+ GY G G GGGGY
Sbjct: 507 GSSGGGYG-GGSSSGGHGGSSSGGYGGGSSGGGGGGY 542
Score = 68.2 bits (165), Expect = 5e-11
Identities = 48/102 (47%), Positives = 55/102 (53%), Gaps = 13/102 (12%)
Query: 1170 GSGYRRGG---SSYSGGGYGGGY---SSGGYGS-GGYGGSANSFRAGYGAGVGGGYRGVS 1222
G G+ GG S+S G GGG SSGGYG GG+GG SFR YG+ GG G S
Sbjct: 44 GGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGG--SFRGSYGSSSFGGSYGGS 101
Query: 1223 RGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQG 1264
GG G+ GG G GG G GGF GG G +G G+ G G
Sbjct: 102 FGG--GSFGGGSFG--GGSFGGGGFGGGGFGGGFGGGFGGDG 139
Score = 66.2 bits (160), Expect = 2e-10
Identities = 44/96 (45%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 1176 GGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNS-GGDY 1234
GG SGG GG +S G G G +GGS+ GYG G+GG G RG + +S GG Y
Sbjct: 44 GGGFSSGGFSGGSFSRGSSGGGCFGGSS----GGYG-GLGGFGGGSFRGSYGSSSFGGSY 98
Query: 1235 RGPSGGYRGSGGFQRGG--GRGAYGTGYFGQGRGGG 1268
G GG GG GG G G +G G FG G GGG
Sbjct: 99 GGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGG 134
Score = 65.5 bits (158), Expect = 3e-10
Identities = 42/104 (40%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 1170 GSGYRRGGSSYSGGGYGGGYSSGGYGSGGYG-GSANSFRAGYGAGVGGGYRGVSRGGFRG 1228
G G S S G GGG+SSGG+ G + GS+ G +G GG G G FRG
Sbjct: 28 GGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRG 87
Query: 1229 NSG-GDYRGPSGGYRGSGGFQRGG-GRGAYGTGYFGQGRGGGGY 1270
+ G + G GG G G F G G G++G G FG G GGG+
Sbjct: 88 SYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGF 131
Score = 64.7 bits (156), Expect = 5e-10
Identities = 52/126 (41%), Positives = 58/126 (46%), Gaps = 33/126 (26%)
Query: 1166 RYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGG 1225
RY + Y SS SGGG GGG G GG GG +S R G GG G S GG
Sbjct: 4 RYSSSKHY---SSSRSGGGGGGG------GCGG-GGGVSSLRISSSKGSLGG--GFSSGG 51
Query: 1226 FRGNS-------GGDYRGPSGGYRGSGGFQRGGGRGAYGT-------------GYFGQGR 1265
F G S GG + G SGGY G GGF G RG+YG+ G FG G
Sbjct: 52 FSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGS 111
Query: 1266 -GGGGY 1270
GGG +
Sbjct: 112 FGGGSF 117
Score = 53.9 bits (128), Expect = 9e-07
Identities = 37/79 (46%), Positives = 42/79 (53%), Gaps = 6/79 (7%)
Query: 1176 GGSS--YSG-GGYGGGYSSGGYGSGGYGGS-ANSFRAGYGAGVGGGYRGVSRGGFRGNSG 1231
GGSS Y G GG+GGG G YGS +GGS SF G G+ GG + G S GG G
Sbjct: 68 GGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSF--GGGSFGGGSFGGGSFGGGGFGGG 125
Query: 1232 GDYRGPSGGYRGSGGFQRG 1250
G G GG+ G GG G
Sbjct: 126 GFGGGFGGGFGGDGGLLSG 144
Score = 51.2 bits (121), Expect = 6e-06
Identities = 31/77 (40%), Positives = 38/77 (49%), Gaps = 14/77 (18%)
Query: 1170 GSGYRRG--GSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFR 1227
G G RG GSS GG YGG + G +G G +GG G+ GGG+ G GGF
Sbjct: 81 GGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGG---------GSFGGGGFGG---GGFG 128
Query: 1228 GNSGGDYRGPSGGYRGS 1244
G GG + G G G+
Sbjct: 129 GGFGGGFGGDGGLLSGN 145
Score = 46.2 bits (108), Expect = 2e-04
Identities = 31/67 (46%), Positives = 33/67 (49%), Gaps = 5/67 (7%)
Query: 1205 SFRAGYGAGVGGGYRGVS-RGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQ 1263
S G G+ GGG G S GG+ G S G G SGG G GG G G YG G G
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGG--GSSGG--GHGGGHGGSSGGGYGGGSSGG 506
Query: 1264 GRGGGGY 1270
G GGGY
Sbjct: 507 GSSGGGY 513
Score = 40.0 bits (92), Expect = 0.014
Identities = 33/89 (37%), Positives = 41/89 (46%), Gaps = 15/89 (16%)
Query: 1151 GSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGS--GGYGGSANSFRA 1208
GS+ G G + SG GGSS GGG GG SSGG S GGYGG ++S
Sbjct: 507 GSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS--- 563
Query: 1209 GYGAGVGGGYRGVSRGGFRGNSGGDYRGP 1237
GG++ S G +S +GP
Sbjct: 564 -------GGHKSSSSGSVGESSS---KGP 582
Score = 33.9 bits (76), Expect = 1.0
Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 4/54 (7%)
Query: 1218 YRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGR--GAYGTGYFGQGRGGGG 1269
YR + G G+SGG RG G GG GGG G +G G+ G GG G
Sbjct: 449 YRSLLEG--EGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYG 500
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 85.5 bits (210), Expect = 3e-16
Identities = 55/110 (50%), Positives = 60/110 (54%), Gaps = 10/110 (9%)
Query: 1161 PPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVG-GGYR 1219
PP R + G G RGG GGG G G GG G GG+GG + G G G G GG
Sbjct: 323 PPWQKRQEGGGG--RGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG 380
Query: 1220 GVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
G RGGF+G GDY G GGY G GG+ GGRG YG Y G G GGGG
Sbjct: 381 GGGRGGFQGR--GDY-GGRGGYGGRGGY---GGRG-YGDPYGGGGGGGGG 423
Score = 53.5 bits (127), Expect = 1e-06
Identities = 40/86 (46%), Positives = 45/86 (52%), Gaps = 18/86 (20%)
Query: 1192 GGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGF--QR 1249
GG G GG+GG G G G GGG G RGG+ G GG GG G GG+
Sbjct: 331 GGGGRGGWGGG------GGGGGRGGGGGGGGRGGWGGGGGGW----GGGGGGGGGWGGGG 380
Query: 1250 GGGRGAY-GTGYFGQGRGG----GGY 1270
GGGRG + G G +G GRGG GGY
Sbjct: 381 GGGRGGFQGRGDYG-GRGGYGGRGGY 405
Score = 32.3 bits (72), Expect = 3.0
Identities = 17/30 (56%), Positives = 17/30 (56%), Gaps = 3/30 (10%)
Query: 1170 GSGYRRGGSSYSGGGYGGGYSSGGYGSGGY 1199
G G R G Y GGG GGG GG G GGY
Sbjct: 404 GYGGRGYGDPYGGGGGGGG---GGGGGGGY 430
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 83.6 bits (205), Expect = 1e-15
Identities = 51/102 (50%), Positives = 55/102 (53%), Gaps = 5/102 (4%)
Query: 1170 GSGYRRGGSSYSGGGYGGGYSSGGYGSGG--YGGSANSFRAGYGAGVGGGY-RGVSRGGF 1226
GS Y GG SY GG GGG G YGSGG YG S+ +G G G G Y G S GG+
Sbjct: 529 GSSYGSGGGSYGSGGGGGG-GRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY 587
Query: 1227 RGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGG 1268
RG SGG G SGG RGSGG GG G G+ G GG
Sbjct: 588 RGGSGGGGGGSSGG-RGSGGGSSGGSIGGRGSSSGGVKSSGG 628
Score = 66.6 bits (161), Expect = 1e-10
Identities = 47/99 (47%), Positives = 53/99 (53%), Gaps = 19/99 (19%)
Query: 1178 SSYSGGGYGGGYSSGGYGSGG--YGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYR 1235
++ SGGG GG GGYGSGG YG S+ G G G GGG RG + SGG
Sbjct: 510 TTISGGGSRGG-GGGGYGSGGSSYGSGGGSY--GSGGGGGGG-----RGSY--GSGGSSY 559
Query: 1236 GPSGGYRGSGGFQRGGGRGAYGT-----GYFGQGRGGGG 1269
G GG GSGG GGG G+YG+ GY G GGGG
Sbjct: 560 GSGGGSYGSGG--GGGGHGSYGSGSSSGGYRGGSGGGGG 596
Score = 64.7 bits (156), Expect = 5e-10
Identities = 51/143 (35%), Positives = 60/143 (41%), Gaps = 41/143 (28%)
Query: 1166 RYDNGSGYRRGGSSYSG-------------------GGYGGGYSSGGYGSGGYG------ 1200
++ + SGYR GG SG GG GG +SS G G G +G
Sbjct: 4 QFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFG 63
Query: 1201 -------GSANSFR------AGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGF 1247
G + S G G+G GGGY G GG G GG + G G G GGF
Sbjct: 64 SRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGG-GGFGGGGFGGGGIGGGGFGGF 122
Query: 1248 QRGGGRGAYGTGYFGQGRGGGGY 1270
G G G +G G FG G GGGY
Sbjct: 123 --GSGGGGFGGGGFGGGGYGGGY 143
Score = 62.0 bits (149), Expect = 3e-09
Identities = 42/99 (42%), Positives = 49/99 (49%), Gaps = 10/99 (10%)
Query: 1151 GSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGY 1210
GS G G + + GS Y GG SY GG GGG+ G YGS G S+ +R G
Sbjct: 537 GSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGH--GSYGS---GSSSGGYRGGS 591
Query: 1211 GAGVGGGYRGVSRGGFRGNSGGDYRG---PSGGYRGSGG 1246
G G GG G GG G+SGG G SGG + SGG
Sbjct: 592 GGGGGGSSGGRGSGG--GSSGGSIGGRGSSSGGVKSSGG 628
Score = 61.2 bits (147), Expect = 6e-09
Identities = 37/83 (44%), Positives = 41/83 (49%), Gaps = 20/83 (24%)
Query: 1175 RGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDY 1234
RGG G G+GGGY GG+G GG+GG G GGG G+ GGF G G
Sbjct: 82 RGGGR--GSGFGGGYGGGGFGGGGFGGG----------GFGGG--GIGGGGFGGFGSG-- 125
Query: 1235 RGPSGGYRGSGGFQRGGGRGAYG 1257
GG G GGF GG G YG
Sbjct: 126 ----GGGFGGGGFGGGGYGGGYG 144
Score = 55.5 bits (132), Expect = 3e-07
Identities = 36/80 (45%), Positives = 43/80 (53%), Gaps = 14/80 (17%)
Query: 1170 GSGYRRGGSSYSGGGYGGG-YSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRG 1228
GSG+ G Y GGG+GGG + GG+G GG GG G+G+G GGG+ G GGF
Sbjct: 87 GSGF---GGGYGGGGFGGGGFGGGGFGGGGIGGGGFG---GFGSG-GGGFGG---GGF-- 134
Query: 1229 NSGGDYRGPSGGYRGSGGFQ 1248
GG Y G G GG Q
Sbjct: 135 -GGGGYGGGYGPVCPPGGIQ 153
Score = 50.4 bits (119), Expect = 1e-05
Identities = 29/63 (46%), Positives = 33/63 (52%), Gaps = 7/63 (11%)
Query: 1214 VGGGYRGVSRGGFRGNSGGDY------RGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGG 1267
V + +S GG RG GG Y G GG GSGG GGGRG+YG+G G GG
Sbjct: 505 VSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGG-GGGGGRGSYGSGGSSYGSGG 563
Query: 1268 GGY 1270
G Y
Sbjct: 564 GSY 566
Score = 37.4 bits (85), Expect = 0.092
Identities = 28/83 (33%), Positives = 32/83 (38%), Gaps = 10/83 (12%)
Query: 1151 GSTRYGDGPRPPKMARYDNGS---GYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFR 1207
G YG G Y +GS GYR G GG GG S GG G GG +S
Sbjct: 562 GGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSG 621
Query: 1208 AGYGAG-------VGGGYRGVSR 1223
+G V Y GV+R
Sbjct: 622 GVKSSGGSSSVKFVSTTYSGVTR 644
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 74.3 bits (181), Expect = 7e-13
Identities = 44/105 (41%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 1170 GSGYRRGGSSYSGGGY--GGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFR 1227
G G GGSS SG GY GGGYS GG G G GG G G G GG + GG
Sbjct: 38 GGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSS 97
Query: 1228 GNSGGDYR---GPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
G G + G SG + GG GGG G + +G G GG G
Sbjct: 98 GGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSG 142
Score = 68.9 bits (167), Expect = 3e-11
Identities = 39/93 (41%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 1181 SGGGYGGGYSSGG----YGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRG 1236
SGGG GGG S GG +G GG GG ++ GY G G G G G GG G
Sbjct: 20 SGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGG 79
Query: 1237 PSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
GG GS + GGG G+G F G GG G
Sbjct: 80 CGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSG 112
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/112 (42%), Positives = 53/112 (47%), Gaps = 10/112 (8%)
Query: 1166 RYDNGSGYRRGGSS--YSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSR 1223
+Y G G GGS SGGG G +SSGG GS G G S G +G G G
Sbjct: 89 KYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGG 148
Query: 1224 GGFRGNS------GGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
GGF G + GG G S G GSG F GGG G+ GY G G G GG
Sbjct: 149 GGFSGQAVQCQSYGGVSSGGSSG-GGSGCFSSGGGGGSV-CGYSGGGSGCGG 198
Score = 64.7 bits (156), Expect = 5e-10
Identities = 48/110 (43%), Positives = 52/110 (47%), Gaps = 18/110 (16%)
Query: 1170 GSGYRRGGSSYSGGGYGGGYSSG---GY-GSGGYGGSANSFRAGYGAGVGGGYRGVSRGG 1225
G G GG + GGG GG SSG GY G GGY G G G G GG G GG
Sbjct: 26 GGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSG------GGCGGGSSGGGGGGGIGG 79
Query: 1226 FRGNSGGDYR-----GPSGGYRGSGGFQR-GGGRGAYGTGYFGQGRGGGG 1269
G SGG + G SGG GSG F GGG G + +G G GG G
Sbjct: 80 CGGGSGGSVKYSGGGGSSGG--GSGCFSSGGGGSGCFSSGGGGSSGGGSG 127
Score = 61.6 bits (148), Expect = 5e-09
Identities = 41/107 (38%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 1170 GSGYRRGGS-SYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRG 1228
G G GGS YSGGG G SG + SGG G S G +G G G GG G
Sbjct: 79 GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSG 138
Query: 1229 NSGGDYRGPSGGYRGS-------GGFQRGGGRGAYGTGYFGQGRGGG 1268
G + GG+ G GG GG G G+G F G GGG
Sbjct: 139 GGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGG-GSGCFSSGGGGG 184
Score = 59.3 bits (142), Expect = 2e-08
Identities = 44/111 (39%), Positives = 50/111 (45%), Gaps = 19/111 (17%)
Query: 1167 YDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGY-GGSANSFR-AGYGAGVGGGYRGVSRG 1224
Y G GY GG GG GGG GG G GG GGS S + +G G GGG S G
Sbjct: 53 YSGGGGYSGGGCG--GGSSGGG---GGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG 107
Query: 1225 G-----FRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGGY 1270
G F GG G SG + GG GGG G + + GGGG+
Sbjct: 108 GGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSS-------GGGGF 151
Score = 58.2 bits (139), Expect = 5e-08
Identities = 47/125 (37%), Positives = 55/125 (44%), Gaps = 28/125 (22%)
Query: 1170 GSG-YRRGGSSYSG--------GGYGGGYSSGG----YGSGGYGGSANSFRAGYGAGVGG 1216
GSG + GG +SG GG G SSGG + SGG GGS + G G+G GG
Sbjct: 140 GSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGG-GSGCGG 198
Query: 1217 GYRGVSRGGFRGNS-------------GGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQ 1263
G G S G+ + GG G GG GSG F GGG G+ G G
Sbjct: 199 GSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSG-GGGSGGSGCFSSGGGGGSSGCGGGSS 257
Query: 1264 GRGGG 1268
G G G
Sbjct: 258 GIGSG 262
Score = 55.1 bits (131), Expect = 4e-07
Identities = 48/128 (37%), Positives = 54/128 (42%), Gaps = 33/128 (25%)
Query: 1170 GSG-YRRGGSSYSGGGYG------GGYSS--------GGYGSGGY-GGSANSFRAGYGAG 1213
GSG + GG SGGG G GG+S GG SGG GG + F +G G G
Sbjct: 125 GSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGG 184
Query: 1214 VGGGYRGVSRGGFRGNSGGDYRG-------------PSGGYRGSGGFQRGGGRGAYGTGY 1260
GY G G G+SGG G P Y GG GGG G G+G
Sbjct: 185 SVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSY--GGGSSGGGGSG--GSGC 240
Query: 1261 FGQGRGGG 1268
F G GGG
Sbjct: 241 FSSGGGGG 248
Score = 50.1 bits (118), Expect = 1e-05
Identities = 45/121 (37%), Positives = 49/121 (40%), Gaps = 27/121 (22%)
Query: 1171 SGYRRGGSS--YSGGGYGG---GYSSGGYGSGG--YGGSANSF-------------RAGY 1210
SG GG S +S GG GG GYS GG G GG GGS + + + Y
Sbjct: 166 SGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSY 225
Query: 1211 GAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRG----GGRGAYGTGYFGQGRG 1266
G G GG G F GG G SG GS G G GG G G G G G
Sbjct: 226 GGGSSGGGGSGGSGCFSSGGGG---GSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGG 282
Query: 1267 G 1267
G
Sbjct: 283 G 283
Score = 49.7 bits (117), Expect = 2e-05
Identities = 45/124 (36%), Positives = 52/124 (41%), Gaps = 30/124 (24%)
Query: 1167 YDNGSGYRRGGS--SYSGGGYG-GGYSSGGYGSG----------------GYGGSANSFR 1207
+ +G G GGS YSGGG G GG SSGG GSG YGG ++
Sbjct: 177 FSSGGG---GGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSG-- 231
Query: 1208 AGYGAGVGGGYRGVSRGGFRGNSGGDYRGP-----SGGYRGSGGFQRGGGRGAYGTGYFG 1262
G G+G G + GG G GG SGG GG GGG G G G
Sbjct: 232 -GGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSG 290
Query: 1263 QGRG 1266
G+G
Sbjct: 291 SGKG 294
Score = 33.5 bits (75), Expect = 1.3
Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 1170 GSGYRRGGSSYSGGGY---GGGYSSGGYGSGGYGGSANSFRAGYGAGV 1214
GS GGSS G G GGG GG SGG GG ++ +G G GV
Sbjct: 248 GSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGV 295
Score = 30.8 bits (68), Expect = 8.6
Identities = 19/42 (45%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 1229 NSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGGY 1270
+ GG G SGG G GF GGG G +G GGGGY
Sbjct: 20 SGGGGGGGGSGG--GGCGFFGGGGSGGGSSGSGCGYSGGGGY 59
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 72.8 bits (177), Expect = 2e-12
Identities = 55/152 (36%), Positives = 65/152 (42%), Gaps = 23/152 (15%)
Query: 1134 MIRQISRPSAAGINLMIGSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYG------- 1186
M RQ S+ S G G + G + G+G G GG+G
Sbjct: 1 MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60
Query: 1187 GGYSS-------GGYGSGGYGGSANS--FRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGP 1237
GG S GG +GG+GG +S F GYG G G GY G GGF G RG
Sbjct: 61 GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGG-----RGM 115
Query: 1238 SGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
GG+ G+GGF GG G G G FG G GG
Sbjct: 116 GGGFGGAGGF--GGAGGFGGAGGFGGPGGFGG 145
Score = 68.9 bits (167), Expect = 3e-11
Identities = 46/94 (48%), Positives = 54/94 (57%), Gaps = 15/94 (15%)
Query: 1176 GGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYR 1235
GGS GG+GGG SS + +GGYGG F +GYG G GGG+ GG RG GG
Sbjct: 73 GGSR--AGGFGGGRSSCAF-AGGYGGG---FGSGYGGGFGGGF-----GGGRGMGGG--F 119
Query: 1236 GPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
G +GG+ G+GGF GG G G G FG G GG
Sbjct: 120 GGAGGFGGAGGF--GGAGGFGGPGGFGGSGGFGG 151
Score = 60.1 bits (144), Expect = 1e-08
Identities = 40/83 (48%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 1178 SSYSGGGYGGGYSSG-GYGSGGY----GGSANSFRAGYGAGVGGGYRGVSRGGFRGNSG- 1231
+S S GGYGGGY G G G GG GGS + F G G G+GGG+ G S GF G SG
Sbjct: 531 TSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGS-SGFSGGSGF 589
Query: 1232 GDYRGPSGGYRGSGGFQRGGGRG 1254
G G G G GGF RG
Sbjct: 590 GSISGARYGVSG-GGFSSASNRG 611
Score = 53.1 bits (126), Expect = 2e-06
Identities = 35/80 (43%), Positives = 40/80 (50%), Gaps = 12/80 (15%)
Query: 1190 SSGGYGSGGYGGSANSFRAGYGAGVGGGYR--GVSRGGFRGNSGGDYRGPSGGYRGSGGF 1247
S+GGYG GGYGG G G G+GGG+ G S GF GG G GG GS GF
Sbjct: 534 SAGGYG-GGYGG-------GMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGG--GSSGF 583
Query: 1248 QRGGGRGAYGTGYFGQGRGG 1267
G G G+ +G GG
Sbjct: 584 SGGSGFGSISGARYGVSGGG 603
Score = 52.4 bits (124), Expect = 3e-06
Identities = 42/102 (41%), Positives = 48/102 (47%), Gaps = 28/102 (27%)
Query: 1172 GYRRGGSSYSGGGYGGGYSSG---GYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRG 1228
GY G S GGG+GGG+ G G G GG G G G GG+ G GGF
Sbjct: 92 GYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAG----------GFGGAGGFGGA--GGF-- 137
Query: 1229 NSGGDYRGPSGGYRGSGGFQRGGGRGAYGT-GYFGQGRGGGG 1269
G GG+ GSGGF GG G+ G+ G FG G GG
Sbjct: 138 -------GGPGGFGGSGGF---GGPGSLGSPGGFGPGGFPGG 169
Score = 52.4 bits (124), Expect = 3e-06
Identities = 42/117 (35%), Positives = 50/117 (42%), Gaps = 28/117 (23%)
Query: 1141 PSAAGINLMIGSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGG-----YG 1195
PSA I+++ ST + GY G GGG GGG+S+GG +G
Sbjct: 518 PSAVSISVVSSSTTSA------------SAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFG 565
Query: 1196 SGGYGGSANSFRAGYGAGVGGGYRGVSRG-GFRGNSGGDYRGPSGGYRGSGGFQRGG 1251
GG G G G G GGG G S G GF SG Y GG+ S RGG
Sbjct: 566 RGGGG--------GIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGF--SSASNRGG 612
Score = 36.6 bits (83), Expect = 0.16
Identities = 22/43 (51%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 1228 GNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGGY 1270
G GG Y G GG G GGF GGG G+ G G G G GGG+
Sbjct: 536 GGYGGGYGGGMGGGLG-GGFSAGGGSGS-GFGRGGGGGIGGGF 576
Score = 36.2 bits (82), Expect = 0.20
Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 16/73 (21%)
Query: 1167 YDNGSGYRRGGSSYSGGGYGGGYSSGGYGS----------GGYGGSANSFRAGYGA-GVG 1215
Y G G GG GGG+GG GG G GG+GGS G+G G
Sbjct: 101 YGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGS-----GGFGGPGSL 155
Query: 1216 GGYRGVSRGGFRG 1228
G G GGF G
Sbjct: 156 GSPGGFGPGGFPG 168
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 72.0 bits (175), Expect = 3e-12
Identities = 45/122 (36%), Positives = 55/122 (45%), Gaps = 9/122 (7%)
Query: 1151 GSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGY 1210
GS +G G + + + RGG+ GG+GG GGYG G G + GY
Sbjct: 198 GSGNFGGG----RGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGY 253
Query: 1211 GAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQ--RGGGRGAYGTGYFGQGRGGG 1268
G G G GY G SRG G+ G Y GY GSG + GG G +G G GGG
Sbjct: 254 GGG-GPGYSGGSRG--YGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGG 310
Query: 1269 GY 1270
Y
Sbjct: 311 SY 312
Score = 68.6 bits (166), Expect = 4e-11
Identities = 45/111 (40%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
Query: 1167 YDNGSGYRRGGSSYSGGGYGGGYSSGGYGS--GGYGGSA--NSFRAGYGAGVGGGYRGVS 1222
+ N GY GG YSGG G G GYG+ GYGGS +S+ G G G GGG
Sbjct: 247 FGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNF 306
Query: 1223 RGGFRGNSGGDYRGPSGGYRGSGGFQRGG-GRGAYGTG--YFGQGRGGGGY 1270
GG N G+Y S + G GG G YG G YF + R GGY
Sbjct: 307 GGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGY 357
Score = 64.3 bits (155), Expect = 7e-10
Identities = 48/111 (43%), Positives = 52/111 (46%), Gaps = 23/111 (20%)
Query: 1175 RGGSSYSGGGYGGGYSS------GGY--GSGGYGGSANSFRAGYGAGVGGGYRGVSRGGF 1226
R GS GGG GGG+ GG G GG+GGS GYG G G GY G G
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG--GGYG-GSGDGYNGFGNDGG 252
Query: 1227 RGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGR-------GGGGY 1270
G G Y G S GY GSG G G G G+GY G G GGGG+
Sbjct: 253 YGGGGPGYSGGSRGY-GSG----GQGYGNQGSGYGGSGSYDSYNNGGGGGF 298
Score = 63.2 bits (152), Expect = 2e-09
Identities = 43/95 (45%), Positives = 48/95 (50%), Gaps = 5/95 (5%)
Query: 1178 SSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYR-- 1235
SS G G G GG G GG+GG+ N R G +G GG+ G GG G SG Y
Sbjct: 190 SSSQRGRSGSGNFGGGRG-GGFGGNDNFGRGGNFSG-RGGFGGSRGGGGYGGSGDGYNGF 247
Query: 1236 GPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGGY 1270
G GGY G G GG RG YG+G G G G GY
Sbjct: 248 GNDGGYGGGGPGYSGGSRG-YGSGGQGYGNQGSGY 281
Score = 54.3 bits (129), Expect = 7e-07
Identities = 40/121 (33%), Positives = 51/121 (42%), Gaps = 19/121 (15%)
Query: 1151 GSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGY 1210
GS YG G G GY GS Y G G Y++GG GG+GG + S G
Sbjct: 263 GSRGYGSG-----------GQGYGNQGSGYGGSGSYDSYNNGG--GGGFGGGSGSNFGGG 309
Query: 1211 GAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGG--FQRGGGRGAYG----TGYFGQG 1264
G+ G F GG++ G S G G GG F + +G YG + +G G
Sbjct: 310 GSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSG 369
Query: 1265 R 1265
R
Sbjct: 370 R 370
Score = 47.0 bits (110), Expect = 1e-04
Identities = 29/67 (43%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 1202 SANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYF 1261
+++S R G+G GG RG GGF GN G G G GG + GGG G G GY
Sbjct: 189 ASSSQRGRSGSGNFGGGRG---GGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYN 245
Query: 1262 GQGRGGG 1268
G G GG
Sbjct: 246 GFGNDGG 252
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,006,445
Number of Sequences: 37866
Number of extensions: 2621616
Number of successful extensions: 24580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 227
Number of HSP's successfully gapped in prelim test: 237
Number of HSP's that attempted gapping in prelim test: 11349
Number of HSP's gapped (non-prelim): 4850
length of query: 1270
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1156
effective length of database: 13,930,794
effective search space: 16103997864
effective search space used: 16103997864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.