Search of human proteins with 18490987

Search of human proteins with 18490987

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18490987 mRNA turnover 4 homolog [Homo sapiens]
         (239 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18490987 mRNA turnover 4 homolog [Homo sapiens]                    482   e-136
gi|4506667 ribosomal protein P0 [Homo sapiens]                         60   1e-09
gi|16933546 ribosomal protein P0 [Homo sapiens]                        60   1e-09
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni...    31   0.83 
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit...    31   0.83 
gi|56549696 E1A binding protein p400 [Homo sapiens]                    31   1.1  
gi|126032348 hect domain and RLD 2 [Homo sapiens]                      30   1.8  
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     30   1.8  
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             30   1.8  
gi|166795262 AE binding protein 2 isoform a [Homo sapiens]             30   1.8  
gi|24308295 GrpE-like 1, mitochondrial [Homo sapiens]                  29   4.1  
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    28   7.0  
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    28   7.0  
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr...    28   7.0  

>gi|18490987 mRNA turnover 4 homolog [Homo sapiens]
          Length = 239

 Score =  482 bits (1240), Expect = e-136
 Identities = 239/239 (100%), Positives = 239/239 (100%)

Query: 1   MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAW 60
           MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAW
Sbjct: 1   MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAW 60

Query: 61  KHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYT 120
           KHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYT
Sbjct: 61  KHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYT 120

Query: 121 EMDYARAGNKAAFTVSLDPGPLEQFPHSMEPQLRQLGLPTALKRGVVTLLSDYEVCKEGD 180
           EMDYARAGNKAAFTVSLDPGPLEQFPHSMEPQLRQLGLPTALKRGVVTLLSDYEVCKEGD
Sbjct: 121 EMDYARAGNKAAFTVSLDPGPLEQFPHSMEPQLRQLGLPTALKRGVVTLLSDYEVCKEGD 180

Query: 181 VLTPEQARVLKLFGYEMAEFKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDDD 239
           VLTPEQARVLKLFGYEMAEFKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDDD
Sbjct: 181 VLTPEQARVLKLFGYEMAEFKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDDD 239


>gi|4506667 ribosomal protein P0 [Homo sapiens]
          Length = 317

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 47/191 (24%), Positives = 85/191 (44%), Gaps = 4/191 (2%)

Query: 23  KQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWKHSRM-FFGKNKVMMVALGRSP 81
           K N   ++ + +D Y   FI    N+ + +++ IR + +   +   GKN +M  A+    
Sbjct: 10  KSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHL 69

Query: 82  SDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYTEMDYARAGNKAAFTVSLDPGP 141
             E    L ++   +RG VG +FT     E+ +          ARAG  A   V++ P  
Sbjct: 70  --ENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTV-PAQ 126

Query: 142 LEQFPHSMEPQLRQLGLPTALKRGVVTLLSDYEVCKEGDVLTPEQARVLKLFGYEMAEFK 201
                       + LG+ T + RG + +LSD ++ K GD +   +A +L +       F 
Sbjct: 127 NTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFG 186

Query: 202 VTIKYMWDSQS 212
           + I+ ++D+ S
Sbjct: 187 LVIQQVFDNGS 197


>gi|16933546 ribosomal protein P0 [Homo sapiens]
          Length = 317

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 47/191 (24%), Positives = 85/191 (44%), Gaps = 4/191 (2%)

Query: 23  KQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWKHSRM-FFGKNKVMMVALGRSP 81
           K N   ++ + +D Y   FI    N+ + +++ IR + +   +   GKN +M  A+    
Sbjct: 10  KSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHL 69

Query: 82  SDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYTEMDYARAGNKAAFTVSLDPGP 141
             E    L ++   +RG VG +FT     E+ +          ARAG  A   V++ P  
Sbjct: 70  --ENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTV-PAQ 126

Query: 142 LEQFPHSMEPQLRQLGLPTALKRGVVTLLSDYEVCKEGDVLTPEQARVLKLFGYEMAEFK 201
                       + LG+ T + RG + +LSD ++ K GD +   +A +L +       F 
Sbjct: 127 NTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFG 186

Query: 202 VTIKYMWDSQS 212
           + I+ ++D+ S
Sbjct: 187 LVIQQVFDNGS 197


>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform b [Homo sapiens]
          Length = 998

 Score = 31.2 bits (69), Expect = 0.83
 Identities = 13/39 (33%), Positives = 26/39 (66%)

Query: 200 FKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDD 238
           FK   K +++ ++ + Q+M ++  ES+S S+EE + ED+
Sbjct: 332 FKNKEKMLYEEETPKSQEMEEENKESSSSSSEEEEGEDE 370


>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform a [Homo sapiens]
          Length = 982

 Score = 31.2 bits (69), Expect = 0.83
 Identities = 13/39 (33%), Positives = 26/39 (66%)

Query: 200 FKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDD 238
           FK   K +++ ++ + Q+M ++  ES+S S+EE + ED+
Sbjct: 332 FKNKEKMLYEEETPKSQEMEEENKESSSSSSEEEEGEDE 370


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 4/69 (5%)

Query: 79   RSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFT-KYTEMDYARAGN--KAAF-T 134
            R+PS+E +D  H+V  RL          RTK +V +  T KY  +   R  N  KA +  
Sbjct: 1242 RAPSEESQDYYHKVVIRLHRVTQPFILRRTKRDVEKQLTKKYEHVLKCRLSNRQKALYED 1301

Query: 135  VSLDPGPLE 143
            V L PG  E
Sbjct: 1302 VILQPGTQE 1310


>gi|126032348 hect domain and RLD 2 [Homo sapiens]
          Length = 4834

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 9/44 (20%)

Query: 204  IKYMWDSQSGRFQQMGDD---------LPESASESTEESDSEDD 238
            I+  WD+ S    +MG +         LP +A  S E+SD+EDD
Sbjct: 1904 IRVQWDTGSTNSYRMGKEGKYDLKLAELPAAAQPSAEDSDTEDD 1947


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 22/115 (19%)

Query: 143 EQFPHSMEPQLRQLGL---------PTALKRGVVTLLSDYEVCKEGD----VLTPEQAR- 188
           E    + EP +  LGL         PTA    ++   + + VC++G     +L  +QAR 
Sbjct: 179 ENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASF-VCRQGAQFEIMLKAKQARN 237

Query: 189 ----VLKLFGYEMAEFKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDDD 239
                L+   Y    +K   K M   + GR+  + ++  +   +S   SD+EDDD
Sbjct: 238 SQFDFLRFDHYLNPYYKFIQKAM---KEGRYTVLAENKSDEKKKSGVSSDNEDDD 289


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 12/27 (44%), Positives = 18/27 (66%)

Query: 213 GRFQQMGDDLPESASESTEESDSEDDD 239
           G  + M +  PESAS++ E+ D E+DD
Sbjct: 77  GEAETMSEPSPESASQAGEDEDEEEDD 103


>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
          Length = 503

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 12/27 (44%), Positives = 18/27 (66%)

Query: 213 GRFQQMGDDLPESASESTEESDSEDDD 239
           G  + M +  PESAS++ E+ D E+DD
Sbjct: 77  GEAETMSEPSPESASQAGEDEDEEEDD 103


>gi|24308295 GrpE-like 1, mitochondrial [Homo sapiens]
          Length = 217

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 12/118 (10%)

Query: 7   DKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWKHSRMF 66
           ++K     T K  LE K  L E+L++ V+ YK   +    N+R    K +  A  +    
Sbjct: 48  EQKADPPATEKTLLEEKVKLEEQLKETVEKYKRA-LADTENLRQRSQKLVEEAKLYGIQA 106

Query: 67  FGKN-----KVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKY 119
           F K+      V+  A    P +E KD+   +     G V       T+ ++ + FTK+
Sbjct: 107 FCKDLLEVADVLEKATQCVPKEEIKDDNPHLKNLYEGLV------MTEVQIQKVFTKH 158


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 28.1 bits (61), Expect = 7.0
 Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 44/170 (25%)

Query: 11   SLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWK---HSRMFF 67
            SL K  K   ELK N+ E+++  ++                K +D+   W+   H    +
Sbjct: 892  SLAKYLKAVEELKNNVTEDIKMSLE---------------EKSRDVCAKWESLHHELSLY 936

Query: 68   GKNKVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYTEMDYARA 127
             +   + +  G+       DN+ ++ K++  E  L+   RTK  + E             
Sbjct: 937  VQQLKIDIEKGK-----LSDNILKLEKQINKEKKLIRRGRTKGLIKE------------- 978

Query: 128  GNKAAFTVSLDPGPLEQFPHSMEPQLRQL--GLPT-ALKRGVVTLLSDYE 174
             ++A F+   + G L Q  H ME  LR+L   LP+   ++ V  LL DYE
Sbjct: 979  -HEACFS---EEGCLYQLNHHME-VLRELCEELPSQKSQQEVKRLLKDYE 1023


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 28.1 bits (61), Expect = 7.0
 Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 44/170 (25%)

Query: 11   SLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWK---HSRMFF 67
            SL K  K   ELK N+ E+++  ++                K +D+   W+   H    +
Sbjct: 892  SLAKYLKAVEELKNNVTEDIKMSLE---------------EKSRDVCAKWESLHHELSLY 936

Query: 68   GKNKVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYTEMDYARA 127
             +   + +  G+       DN+ ++ K++  E  L+   RTK  + E             
Sbjct: 937  VQQLKIDIEKGK-----LSDNILKLEKQINKEKKLIRRGRTKGLIKE------------- 978

Query: 128  GNKAAFTVSLDPGPLEQFPHSMEPQLRQL--GLPT-ALKRGVVTLLSDYE 174
             ++A F+   + G L Q  H ME  LR+L   LP+   ++ V  LL DYE
Sbjct: 979  -HEACFS---EEGCLYQLNHHME-VLRELCEELPSQKSQQEVKRLLKDYE 1023


>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
           antiproteinase, antitrypsin), member 11 [Homo sapiens]
          Length = 422

 Score = 28.1 bits (61), Expect = 7.0
 Identities = 35/181 (19%), Positives = 75/181 (41%), Gaps = 19/181 (10%)

Query: 1   MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAW 60
           +P  K + KV  +    K L+ +Q+ ++ +++    + +   F+ +     ++ D     
Sbjct: 128 LPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQ 187

Query: 61  KHSRMF-----FGKNKVMMVA-------LGRSPSDEYKDNLHQ---VSKRLRGEVGLLFT 105
            + ++      F ++  M++A         + P   Y+    +   V +R   +V ++  
Sbjct: 188 TYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQ 247

Query: 106 NRTKEEVNEWFTKYTEMDYARAGNKAAFTVSLDPGPLEQFPHSMEPQ-LR---QLGLPTA 161
                 + +     T +     GN  A  V  DPG ++Q   +++PQ LR   QL LP+ 
Sbjct: 248 KEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLLLPSL 307

Query: 162 L 162
           L
Sbjct: 308 L 308


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,789,345
Number of Sequences: 37866
Number of extensions: 371849
Number of successful extensions: 1389
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1376
Number of HSP's gapped (non-prelim): 19
length of query: 239
length of database: 18,247,518
effective HSP length: 99
effective length of query: 140
effective length of database: 14,498,784
effective search space: 2029829760
effective search space used: 2029829760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.