Search of human proteins with 18426967

Search of human proteins with 18426967

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18426967 deoxyguanosine kinase isoform a precursor [Homo
sapiens]
         (277 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18426967 deoxyguanosine kinase isoform a precursor [Homo sapi...   561   e-160
gi|18426971 deoxyguanosine kinase isoform b precursor [Homo sapi...   297   6e-81
gi|4503269 deoxycytidine kinase [Homo sapiens]                        254   6e-68
gi|92859641 thymidine kinase 2, mitochondrial [Homo sapiens]          120   1e-27
gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1...    41   0.001
gi|11342678 amyloid beta (A4) precursor protein-binding, family ...    32   0.47 
gi|24430190 keratin 15 [Homo sapiens]                                  30   1.8  
gi|122056685 peptidylarginine deiminase type I [Homo sapiens]          29   5.2  

>gi|18426967 deoxyguanosine kinase isoform a precursor [Homo
           sapiens]
          Length = 277

 Score =  561 bits (1445), Expect = e-160
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK 60
           MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
Sbjct: 1   MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK 60

Query: 61  TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK 120
           TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
Sbjct: 61  TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK 120

Query: 121 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF 180
           VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
Sbjct: 121 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF 180

Query: 181 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE 240
           ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
Sbjct: 181 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE 240

Query: 241 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL 277
           ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
Sbjct: 241 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL 277


>gi|18426971 deoxyguanosine kinase isoform b precursor [Homo
           sapiens]
          Length = 189

 Score =  297 bits (761), Expect = 6e-81
 Identities = 149/151 (98%), Positives = 149/151 (98%)

Query: 1   MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK 60
           MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
Sbjct: 1   MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK 60

Query: 61  TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK 120
           TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
Sbjct: 61  TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK 120

Query: 121 VQLEPFPEKLLQARKPVQIFERSVYSDRYIF 151
           VQLEPFPEKLLQARKPVQIFERSVYSDR  F
Sbjct: 121 VQLEPFPEKLLQARKPVQIFERSVYSDRLHF 151



 Score = 84.7 bits (208), Expect = 8e-17
 Identities = 41/42 (97%), Positives = 42/42 (100%)

Query: 236 KLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL 277
           +LHFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
Sbjct: 148 RLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL 189


>gi|4503269 deoxycytidine kinase [Homo sapiens]
          Length = 260

 Score =  254 bits (649), Expect = 6e-68
 Identities = 125/263 (47%), Positives = 171/263 (65%), Gaps = 6/263 (2%)

Query: 18  MAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQN 77
           MA  P     S      G   +++SIEGNIA GKSTFV +L +   +W V  EPVA W N
Sbjct: 1   MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCN 60

Query: 78  IQAAGTQ---KACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFPEKLLQAR 134
           +Q+   +      + ++ GN+L MMY +P RWS+TFQT++ LSR++ QL     KL  A 
Sbjct: 61  VQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAE 120

Query: 135 KPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLHGFIYLQA 194
           KPV  FERSVYSDRYIFA NL+E+  +++ EW IYQDWH ++  +F   + L G IYLQA
Sbjct: 121 KPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQA 180

Query: 195 SPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPVLVLDVND 254
           +P+ CL R+Y R R EE+GI L YLE+LH +HE+WL+H+T K +F+ L  +P+L LDVN+
Sbjct: 181 TPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNE 240

Query: 255 DFSEEVTKQEDLMREVNTFVKNL 277
           DF +   K E L+ +V  F+  L
Sbjct: 241 DFKD---KYESLVEKVKEFLSTL 260


>gi|92859641 thymidine kinase 2, mitochondrial [Homo sapiens]
          Length = 307

 Score =  120 bits (302), Expect = 1e-27
 Identities = 70/213 (32%), Positives = 114/213 (53%), Gaps = 27/213 (12%)

Query: 41  LSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMY 100
           + +EGNIA GK+T ++  +    +  V TEPV+ W+N++              N L +MY
Sbjct: 95  ICVEGNIASGKTTCLEFFSNA-TDVEVLTEPVSKWRNVRGH------------NPLGLMY 141

Query: 101 REPARWSYTFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGS 160
            + +RW  T QT+  L+ L     P           V++ ERS++S RYIF +NL+ +G 
Sbjct: 142 HDASRWGLTLQTYVQLTMLDRHTRPQVSS-------VRLMERSIHSARYIFVENLYRSGK 194

Query: 161 LSDIEWHIYQDWHSFLLWEFASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLE 220
           + ++++ +  +W  ++L      + L   +YL+ +P+ C +RL +R REEEK I L YLE
Sbjct: 195 MPEVDYVVLSEWFDWILRNMDVSVDL--IVYLRTNPETCYQRLKKRCREEEKVIPLEYLE 252

Query: 221 QLHGQHEAWLIHKTTKLHFEALMNIPVLVLDVN 253
            +H  HE WLI  +        M  PVLV++ +
Sbjct: 253 AIHHLHEEWLIKGSL-----FPMAAPVLVIEAD 280


>gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10,
           42kDa precursor [Homo sapiens]
          Length = 355

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 47/198 (23%), Positives = 84/198 (42%), Gaps = 22/198 (11%)

Query: 39  RRLSIEGNIAVGKSTFVKLLT-----KTYPEWHVATEPVATWQNIQAAGTQKACTAQSLG 93
           R ++++GNI  GK    K +      K +PE  +      T       G  K       G
Sbjct: 58  RVITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTT-------GDGKPLATDYNG 110

Query: 94  NL-LDMMYREPAR---WSYTFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRY 149
           N  L+  Y +P      SY  Q++ + SRL +Q     E LL   + V + ERS++SD +
Sbjct: 111 NCSLEKFYDDPRSNDGNSYRLQSWLYSSRL-LQYSDALEHLLTTGQGV-VLERSIFSD-F 167

Query: 150 IFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLHGFIYLQASPQVCLKRLYQRARE 209
           +F + ++  G +       Y +  S  + ++   +  H  IY+        +R+ ++   
Sbjct: 168 VFLEAMYNQGFIRKQCVDHYNEVKSVTICDY---LPPHLVIYIDVPVPEVQRRIQKKGDP 224

Query: 210 EEKGIELAYLEQLHGQHE 227
            E  I  AYL+ +   ++
Sbjct: 225 HEMKITSAYLQDIENAYK 242


>gi|11342678 amyloid beta (A4) precursor protein-binding, family A,
           member 3 [Homo sapiens]
          Length = 575

 Score = 32.3 bits (72), Expect = 0.47
 Identities = 14/52 (26%), Positives = 28/52 (53%)

Query: 25  GVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQ 76
           G++   G+  G     ++ +  +A   +  ++LLT+ Y E H+ T P AT++
Sbjct: 513 GIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYR 564


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 173 HSFLLWEFASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIH 232
           H   + EF+S++     + + A+P V L R+    RE+ +    A  E+     EAW   
Sbjct: 244 HEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYE----AMAEKNRRDVEAWFFS 299

Query: 233 KTTKLHFEALMNIPVL 248
           KT +L+ E   N  ++
Sbjct: 300 KTEELNKEVASNTEMI 315


>gi|122056685 peptidylarginine deiminase type I [Homo sapiens]
          Length = 663

 Score = 28.9 bits (63), Expect = 5.2
 Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 168 IYQDW----HSFLLWEFASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLH 223
           +Y DW    H      F       GF  L ASP  CLK L+Q  +EE  G E A  + L 
Sbjct: 463 LYSDWLSVGHVDEFLTFVPTSDQKGFRLLLASPSACLK-LFQEKKEEGYG-EAAQFDGLK 520

Query: 224 GQ 225
            Q
Sbjct: 521 HQ 522


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,127,691
Number of Sequences: 37866
Number of extensions: 434643
Number of successful extensions: 1038
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1027
Number of HSP's gapped (non-prelim): 9
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.