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Search of human proteins with 17978466
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17978466 cyclin T1 [Homo sapiens]
(726 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17978466 cyclin T1 [Homo sapiens] 1471 0.0
gi|17978469 cyclin T2 isoform b [Homo sapiens] 551 e-156
gi|4502629 cyclin T2 isoform a [Homo sapiens] 528 e-150
gi|150417989 cyclin K isoform 1 [Homo sapiens] 147 3e-35
gi|38176158 cyclin K isoform 2 [Homo sapiens] 147 3e-35
gi|88758580 cyclin L2 isoform A [Homo sapiens] 99 2e-20
gi|9945320 cyclin L1 [Homo sapiens] 97 5e-20
gi|221554516 cyclin L2 isoform C [Homo sapiens] 77 7e-14
gi|221554518 cyclin L2 isoform D [Homo sapiens] 76 1e-13
gi|88758578 cyclin L2 isoform B [Homo sapiens] 76 1e-13
gi|196049382 family with sequence similarity 58, member A isofor... 72 2e-12
gi|157502165 family with sequence similarity 58 member B [Homo s... 69 2e-11
gi|61676091 cyclin C isoform a [Homo sapiens] 69 2e-11
gi|196049384 family with sequence similarity 58, member A isofor... 63 1e-09
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 51 3e-06
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 51 3e-06
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 50 1e-05
gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof... 50 1e-05
gi|27894357 nuclear receptor subfamily 4, group A, member 3 isof... 50 1e-05
gi|27894355 nuclear receptor subfamily 4, group A, member 3 isof... 50 1e-05
gi|61676093 cyclin C isoform b [Homo sapiens] 47 8e-05
gi|148762982 hypothetical protein LOC387640 [Homo sapiens] 45 2e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 44 7e-04
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 44 7e-04
gi|149944526 additional sex combs like 3 [Homo sapiens] 43 0.001
gi|4507347 TBP-associated factor 2 [Homo sapiens] 43 0.001
gi|134288896 hypothetical protein LOC143684 [Homo sapiens] 42 0.002
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 42 0.002
gi|110431370 espin [Homo sapiens] 42 0.002
gi|61966923 forkhead box B2 [Homo sapiens] 42 0.002
>gi|17978466 cyclin T1 [Homo sapiens]
Length = 726
Score = 1471 bits (3809), Expect = 0.0
Identities = 726/726 (100%), Positives = 726/726 (100%)
Query: 1 MEGERKNNNKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTIN 60
MEGERKNNNKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTIN
Sbjct: 1 MEGERKNNNKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTIN 60
Query: 61 TAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPD 120
TAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPD
Sbjct: 61 TAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPD 120
Query: 121 TRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATN 180
TRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATN
Sbjct: 121 TRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATN 180
Query: 181 SLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHE 240
SLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHE
Sbjct: 181 SLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHE 240
Query: 241 FLQILEKTPNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLM 300
FLQILEKTPNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLM
Sbjct: 241 FLQILEKTPNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLM 300
Query: 301 SMSTSTTSAVPSLPVSEESSSNLTSVEMLPGKRWLSSQPSFKLEPTQGHRTSENLALTGV 360
SMSTSTTSAVPSLPVSEESSSNLTSVEMLPGKRWLSSQPSFKLEPTQGHRTSENLALTGV
Sbjct: 301 SMSTSTTSAVPSLPVSEESSSNLTSVEMLPGKRWLSSQPSFKLEPTQGHRTSENLALTGV 360
Query: 361 DHSLPQDGSNAFISQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAY 420
DHSLPQDGSNAFISQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAY
Sbjct: 361 DHSLPQDGSNAFISQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAY 420
Query: 421 AAQNLLSHHDSHSSVILKMPIEGSENPERPFLEKADKTALKMRIPVAGGDKAASSKPEEI 480
AAQNLLSHHDSHSSVILKMPIEGSENPERPFLEKADKTALKMRIPVAGGDKAASSKPEEI
Sbjct: 421 AAQNLLSHHDSHSSVILKMPIEGSENPERPFLEKADKTALKMRIPVAGGDKAASSKPEEI 480
Query: 481 KMRIKVHAAADKHNSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNK 540
KMRIKVHAAADKHNSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNK
Sbjct: 481 KMRIKVHAAADKHNSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNK 540
Query: 541 RPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSL 600
RPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSL
Sbjct: 541 RPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSL 600
Query: 601 NFSFPSLPTMGQMPGHSSDTSGLSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDT 660
NFSFPSLPTMGQMPGHSSDTSGLSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDT
Sbjct: 601 NFSFPSLPTMGQMPGHSSDTSGLSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDT 660
Query: 661 VNMLHSLLSAQGVQPTQPTAFEFVRPYSDYLNPRSGGISSRSGNTDKPRPPPLPSEPPPP 720
VNMLHSLLSAQGVQPTQPTAFEFVRPYSDYLNPRSGGISSRSGNTDKPRPPPLPSEPPPP
Sbjct: 661 VNMLHSLLSAQGVQPTQPTAFEFVRPYSDYLNPRSGGISSRSGNTDKPRPPPLPSEPPPP 720
Query: 721 LPPLPK 726
LPPLPK
Sbjct: 721 LPPLPK 726
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 551 bits (1419), Expect = e-156
Identities = 345/740 (46%), Positives = 443/740 (59%), Gaps = 94/740 (12%)
Query: 9 NKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHR 68
+ RW+FTREQLEN+PSRR GV+ DKELS RQQAANL+Q+MGQRLNVSQLTINTAIVYMHR
Sbjct: 8 SSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHR 67
Query: 69 FYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQ 128
FYM SFT+F N ++ ALFLAAKVEEQ +KLEHVIKVAH CLHP E L DT+ +AYLQ
Sbjct: 68 FYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQ 127
Query: 129 QVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFS 188
Q Q+LVILE+I+LQTLGFE+TI+HPHT VVKCTQLVRASKDLAQTSYFMATNSLHLTTF
Sbjct: 128 QTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFC 187
Query: 189 LQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKT 248
LQY P V+ACVCIHLACKWSNWEIPVSTDGKHWWEYVD TVTLELLDELTHEFLQILEKT
Sbjct: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKT 247
Query: 249 PNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTS 308
PNRLK+I NWRA +AA+K K D + ++ +++ S T + S +TS
Sbjct: 248 PNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTS 307
Query: 309 AVPS-LPVS--------EESSSNL---------TSVEMLPGKRWLSSQPSFKLEPTQGHR 350
A P+ +P++ +S NL TS + + W Q S + E +
Sbjct: 308 AFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQK 367
Query: 351 TSENLA----------------LTGVDHSLPQDGSNAFISQKQNSKSVPS---------- 384
+L+ +G+ H + ++ + Q+ K+ S
Sbjct: 368 QETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTP 427
Query: 385 ----AKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMP 440
K+SL +YR K E + + A V+ Q+ S S + +K+P
Sbjct: 428 GIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIP 487
Query: 441 IEGSENPERPFLEKADKT-ALKMRIPVAGGDKAASSKPEEIKMRIKVHAAADKHNSVEDS 499
I N E+ +K +K+ +LK+RIP+ DK+AS EE+KM+IKV +++++H+S ++
Sbjct: 488 I---ANTEKYMADKKEKSGSLKLRIPIPPTDKSASK--EELKMKIKV-SSSERHSSSDEG 541
Query: 500 VTK--------SREHKEKHKTHPSNHHHHHNH-HSHKHSHSQLPVGTGNKRPGDPKHSSQ 550
K SR+HKEKHK HPS+ HH +H HSH HS S G KHS+
Sbjct: 542 SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSS---------SGGSKHSAD 592
Query: 551 --TSNLAHKTYSLSSS--FSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPS 606
+ LSS SSSSS+RKR A +H +K++KS+KSS + S S
Sbjct: 593 GIPPTVLRSPVGLSSDGISSSSSSSRKR---LHVNDASHNHHSKMSKSSKSSG-SSSSSS 648
Query: 607 LPTMGQMPGHSSDTSGLSFSQPSCKTRVPHS------KLDKGPTGANG-------HNTTQ 653
+ H+S + P +V + KLDK P NG ++Q
Sbjct: 649 SSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQ 708
Query: 654 TIDYQDTVNMLHSLLSAQGV 673
+DY+DT +ML SLLSAQG+
Sbjct: 709 HMDYKDTFDMLDSLLSAQGM 728
>gi|4502629 cyclin T2 isoform a [Homo sapiens]
Length = 663
Score = 528 bits (1361), Expect = e-150
Identities = 318/652 (48%), Positives = 404/652 (61%), Gaps = 80/652 (12%)
Query: 9 NKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHR 68
+ RW+FTREQLEN+PSRR GV+ DKELS RQQAANL+Q+MGQRLNVSQLTINTAIVYMHR
Sbjct: 8 SSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHR 67
Query: 69 FYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQ 128
FYM SFT+F N ++ ALFLAAKVEEQ +KLEHVIKVAH CLHP E L DT+ +AYLQ
Sbjct: 68 FYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQ 127
Query: 129 QVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFS 188
Q Q+LVILE+I+LQTLGFE+TI+HPHT VVKCTQLVRASKDLAQTSYFMATNSLHLTTF
Sbjct: 128 QTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFC 187
Query: 189 LQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKT 248
LQY P V+ACVCIHLACKWSNWEIPVSTDGKHWWEYVD TVTLELLDELTHEFLQILEKT
Sbjct: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKT 247
Query: 249 PNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTS 308
PNRLK+I NWRA +AA+K K D + ++ +++ S T + S +TS
Sbjct: 248 PNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTS 307
Query: 309 AVPS-LPVS--------EESSSNL---------TSVEMLPGKRWLSSQPSFKLEPTQGHR 350
A P+ +P++ +S NL TS + + W Q S + E +
Sbjct: 308 AFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQK 367
Query: 351 TSENLA----------------LTGVDHSLPQDGSNAFISQKQNSKSVPS---------- 384
+L+ +G+ H + ++ + Q+ K+ S
Sbjct: 368 QETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTP 427
Query: 385 ----AKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMP 440
K+SL +YR K E + + A V+ Q+ S S + +K+P
Sbjct: 428 GIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIP 487
Query: 441 IEGSENPERPFLEKADKT-ALKMRIPVAGGDKAASSKPEEIKMRIKVHAAADKHNSVEDS 499
I N E+ +K +K+ +LK+RIP+ DK+AS EE+KM+IKV +++++H+S ++
Sbjct: 488 I---ANTEKYMADKKEKSGSLKLRIPIPPTDKSASK--EELKMKIKV-SSSERHSSSDEG 541
Query: 500 VTK--------SREHKEKHKTHPSNHHHHHNH-HSHKHSHSQLPVGTGNKRPGDPKHSSQ 550
K SR+HKEKHK HPS+ HH +H HSH HS S G KHS+
Sbjct: 542 SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSS---------SGGSKHSAD 592
Query: 551 --TSNLAHKTYSLSSS--FSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSS 598
+ LSS SSSSS+RKR A +H +K++KS+KSS
Sbjct: 593 GIPPTVLRSPVGLSSDGISSSSSSSRKR---LHVNDASHNHHSKMSKSSKSS 641
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 147 bits (371), Expect = 3e-35
Identities = 86/259 (33%), Positives = 141/259 (54%), Gaps = 23/259 (8%)
Query: 12 WYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYM 71
WY+ ++ L ++PS+ G+DP E YR++ A + D+G RL + T+ T I+Y HRFYM
Sbjct: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
Query: 72 IQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQE--SLPDTRSEAYLQQ 129
SF QFP LFLA KVEE PKK + +IK A + L+ + D E
Sbjct: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKE----- 138
Query: 130 VQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMA---TNSLHLTT 186
++++LE I+LQT+ F+L ++HP+ ++K + ++ K+ Q MA N TT
Sbjct: 139 --EVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTT 196
Query: 187 FSLQYTPPVVACVCIHLACKWSNWEIPVSTDG---KHWWEYVDATVTLELLDELTHEFL- 242
SLQ+ P ++A ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 197 LSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILD 256
Query: 243 -------QILEKTPNRLKR 254
Q+ TP++L++
Sbjct: 257 LYSQGKQQMPHHTPHQLQQ 275
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 147 bits (371), Expect = 3e-35
Identities = 86/259 (33%), Positives = 141/259 (54%), Gaps = 23/259 (8%)
Query: 12 WYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYM 71
WY+ ++ L ++PS+ G+DP E YR++ A + D+G RL + T+ T I+Y HRFYM
Sbjct: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
Query: 72 IQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQE--SLPDTRSEAYLQQ 129
SF QFP LFLA KVEE PKK + +IK A + L+ + D E
Sbjct: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKE----- 138
Query: 130 VQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMA---TNSLHLTT 186
++++LE I+LQT+ F+L ++HP+ ++K + ++ K+ Q MA N TT
Sbjct: 139 --EVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTT 196
Query: 187 FSLQYTPPVVACVCIHLACKWSNWEIPVSTDG---KHWWEYVDATVTLELLDELTHEFL- 242
SLQ+ P ++A ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 197 LSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILD 256
Query: 243 -------QILEKTPNRLKR 254
Q+ TP++L++
Sbjct: 257 LYSQGKQQMPHHTPHQLQQ 275
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 98.6 bits (244), Expect = 2e-20
Identities = 68/233 (29%), Positives = 117/233 (50%), Gaps = 11/233 (4%)
Query: 17 EQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFT 76
++L +PS G+D D E R L+Q G L + Q+ + T V RF+ +SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 77 QFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLH---PQESLPDTRSEAYLQQVQDL 133
+ V+ A + LA+K+EE P+++ VI V H ++ +P + Y+ +
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176
Query: 134 VILESIILQTLGFELTIDHPHTHVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFSLQY 191
+ E +L+ LGF + + HPH +V Q++ ++ L QTS+ +SL F +++
Sbjct: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVF-VRF 235
Query: 192 TPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQI 244
P +AC CI+LA + EIP+ + HW+ AT E + E+ + LQ+
Sbjct: 236 QPESIACACIYLAAR--TLEIPL-PNRPHWFLLFGATE--EEIQEICLKILQL 283
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 97.1 bits (240), Expect = 5e-20
Identities = 71/240 (29%), Positives = 119/240 (49%), Gaps = 12/240 (5%)
Query: 17 EQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFT 76
E+L +PS + G+D E R L+Q G L + Q+ + T V HRF+ +SF
Sbjct: 62 ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
Query: 77 QFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLH---PQESLPDTRSEAYLQQVQDL 133
+ VA A + LA+K+EE P+++ VI V H + P + Y+ +
Sbjct: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQV 181
Query: 134 VILESIILQTLGFELTIDHPHTHVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFSLQY 191
+ E +L+ LGF + + HPH +V Q++ ++ L QT++ +SL F +++
Sbjct: 182 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVF-VRF 240
Query: 192 TPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQI-LEKTPN 250
P +AC CI+LA + +IP+ T HW ++ T E + E+ E L++ K PN
Sbjct: 241 QPETIACACIYLAAR--ALQIPLPT-RPHW--FLLFGTTEEEIQEICIETLRLYTRKKPN 295
Score = 30.0 bits (66), Expect = 7.9
Identities = 24/135 (17%), Positives = 50/135 (37%), Gaps = 5/135 (3%)
Query: 430 DSHSSVILKMPIEGSENPERPFLEKADKTALKMRIPVAGGDKAASSKPEEIKMRIKVHAA 489
+ S + + + E +R K+ ++ + ++AS + R + H
Sbjct: 349 EEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP 408
Query: 490 ADKHNSVEDSV----TKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDP 545
+N+ ++SR H P HH+H + H K H++ + + N+
Sbjct: 409 RRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHL-KAKHTRDDLKSSNRHGHKR 467
Query: 546 KHSSQTSNLAHKTYS 560
K S S + +S
Sbjct: 468 KKSRSRSQSKSRDHS 482
>gi|221554516 cyclin L2 isoform C [Homo sapiens]
Length = 236
Score = 76.6 bits (187), Expect = 7e-14
Identities = 48/171 (28%), Positives = 85/171 (49%), Gaps = 5/171 (2%)
Query: 17 EQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFT 76
++L +PS G+D D E R L+Q G L + Q+ + T V RF+ +SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 77 QFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLH---PQESLPDTRSEAYLQQVQDL 133
+ V+ A + LA+K+EE P+++ VI V H ++ +P + Y+ +
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176
Query: 134 VILESIILQTLGFELTIDHPHTHVVKCTQLVRASKD--LAQTSYFMATNSL 182
+ E +L+ LGF + + HPH +V Q++ ++ L QTS+ + + L
Sbjct: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWVASEDPL 227
>gi|221554518 cyclin L2 isoform D [Homo sapiens]
Length = 227
Score = 75.9 bits (185), Expect = 1e-13
Identities = 47/164 (28%), Positives = 82/164 (50%), Gaps = 5/164 (3%)
Query: 17 EQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFT 76
++L +PS G+D D E R L+Q G L + Q+ + T V RF+ +SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 77 QFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLH---PQESLPDTRSEAYLQQVQDL 133
+ V+ A + LA+K+EE P+++ VI V H ++ +P + Y+ +
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176
Query: 134 VILESIILQTLGFELTIDHPHTHVVKCTQLVRASKD--LAQTSY 175
+ E +L+ LGF + + HPH +V Q++ ++ L QTS+
Sbjct: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
>gi|88758578 cyclin L2 isoform B [Homo sapiens]
Length = 226
Score = 75.9 bits (185), Expect = 1e-13
Identities = 47/164 (28%), Positives = 82/164 (50%), Gaps = 5/164 (3%)
Query: 17 EQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFT 76
++L +PS G+D D E R L+Q G L + Q+ + T V RF+ +SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 77 QFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLH---PQESLPDTRSEAYLQQVQDL 133
+ V+ A + LA+K+EE P+++ VI V H ++ +P + Y+ +
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176
Query: 134 VILESIILQTLGFELTIDHPHTHVVKCTQLVRASKD--LAQTSY 175
+ E +L+ LGF + + HPH +V Q++ ++ L QTS+
Sbjct: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
>gi|196049382 family with sequence similarity 58, member A isoform 1
[Homo sapiens]
Length = 248
Score = 71.6 bits (174), Expect = 2e-12
Identities = 47/223 (21%), Positives = 102/223 (45%), Gaps = 11/223 (4%)
Query: 31 PDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFL 90
P E + A + + G +L + + I TA H+F+ + + +A ++++L
Sbjct: 20 PAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYL 79
Query: 91 AAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTI 150
A KVEEQ + +I V++ +P P + + +V E ++L+ L F+++
Sbjct: 80 AGKVEEQHLRTRDIINVSNRYFNPSGE-PLELDSRFWELRDSIVQCELLMLRVLRFQVSF 138
Query: 151 DHPHTHVVKCTQLVR--------ASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIH 202
HPH +++ ++ +A T++ + +S H L++ +A ++
Sbjct: 139 QHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYH-GALCLRFQAQHIAVAVLY 197
Query: 203 LACKWSNWEIPVSTDG-KHWWEYVDATVTLELLDELTHEFLQI 244
LA + E+P + K WW+ + +T ++D + + +QI
Sbjct: 198 LALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQI 240
>gi|157502165 family with sequence similarity 58 member B [Homo
sapiens]
Length = 252
Score = 68.6 bits (166), Expect = 2e-11
Identities = 50/217 (23%), Positives = 103/217 (47%), Gaps = 17/217 (7%)
Query: 40 QAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPK 99
+ A + + G +L + + I TA +F+ F +A ++++LA KVEEQP
Sbjct: 33 RVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPL 92
Query: 100 KLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVI-LESIILQTLGFELTIDHPHTHV- 157
+I V++ +P S ++ L +++D ++ E ++L+ L F+++ HPH ++
Sbjct: 93 WAHDIISVSNRYFNP--SSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLL 150
Query: 158 ---------VKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWS 208
+ C R +A T++ + +S H L++ +A V ++LA +
Sbjct: 151 YYLVSLKNWLNCHSWQRT--PVAVTAWALLRDSYH-GGLCLRFQAQHIAVVVLYLALQVY 207
Query: 209 NWEIPVSTDG-KHWWEYVDATVTLELLDELTHEFLQI 244
E+P + K WW+ +T ++D + + +QI
Sbjct: 208 GVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQI 244
>gi|61676091 cyclin C isoform a [Homo sapiens]
Length = 283
Score = 68.6 bits (166), Expect = 2e-11
Identities = 53/209 (25%), Positives = 97/209 (46%), Gaps = 12/209 (5%)
Query: 43 NLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEE-QPKKL 101
N++Q +G+ L + Q I TA VY RFY S +AP +FLA+KVEE
Sbjct: 46 NVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSN 105
Query: 102 EHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCT 161
+I A + L + S + Y ++ ++ E +L+ + L + HP+ +++
Sbjct: 106 TRLIAAATSVLKTRFSYAFPKEFPY--RMNHILECEFYLLELMDCCLIVYHPYRPLLQYV 163
Query: 162 QLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHW 221
Q + +D+ + N + T L Y P ++A C+H+AC + D + W
Sbjct: 164 QDM-GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVAC------VVQQKDARQW 216
Query: 222 WEYVDATVTLELLDELTHEFLQILEKTPN 250
+ + +V +E + E+ L++ E+ N
Sbjct: 217 --FAELSVDMEKILEIIRVILKLYEQWKN 243
>gi|196049384 family with sequence similarity 58, member A isoform 2
[Homo sapiens]
Length = 228
Score = 62.8 bits (151), Expect = 1e-09
Identities = 43/202 (21%), Positives = 91/202 (45%), Gaps = 11/202 (5%)
Query: 31 PDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFL 90
P E + A + + G +L + + I TA H+F+ + + +A ++++L
Sbjct: 20 PAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYL 79
Query: 91 AAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTI 150
A KVEEQ + +I V++ +P P + + +V E ++L+ L F+++
Sbjct: 80 AGKVEEQHLRTRDIINVSNRYFNPSGE-PLELDSRFWELRDSIVQCELLMLRVLRFQVSF 138
Query: 151 DHPHTHVVKCTQLVR--------ASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIH 202
HPH +++ ++ +A T++ + +S H L++ +A ++
Sbjct: 139 QHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYH-GALCLRFQAQHIAVAVLY 197
Query: 203 LACKWSNWEIPVSTDG-KHWWE 223
LA + E+P + K WW+
Sbjct: 198 LALQVYGVEVPAEVEAEKPWWQ 219
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 7/152 (4%)
Query: 491 DKHNSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRP---GDPKH 547
+ H E + + + H H ++ HHHH+HH H H H Q +G RP P +
Sbjct: 571 ETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALG-NRTRPRVYNSPTN 629
Query: 548 SSQTSN---LAHKTYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSF 604
SS T + + H +S++S SS++S+ S G +A +T N +
Sbjct: 630 SSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAM 689
Query: 605 PSLPTMGQMPGHSSDTSGLSFSQPSCKTRVPH 636
T+ P + +G Q S T H
Sbjct: 690 DVNLTVYSNPRQETGIAGHPTYQFSANTGPAH 721
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 7/152 (4%)
Query: 491 DKHNSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRP---GDPKH 547
+ H E + + + H H ++ HHHH+HH H H H Q +G RP P +
Sbjct: 580 ETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALG-NRTRPRVYNSPTN 638
Query: 548 SSQTSN---LAHKTYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSF 604
SS T + + H +S++S SS++S+ S G +A +T N +
Sbjct: 639 SSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAM 698
Query: 605 PSLPTMGQMPGHSSDTSGLSFSQPSCKTRVPH 636
T+ P + +G Q S T H
Sbjct: 699 DVNLTVYSNPRQETGIAGHPTYQFSANTGPAH 730
>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
b [Homo sapiens]
Length = 637
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 28/214 (13%)
Query: 514 PSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRK 573
PS HHHHH+HH H H H Q +++P P SS + T S+ T
Sbjct: 103 PSYHHHHHHHHHHHHHHQQ-----QHQQPSIPPASSPEDEVLPSTSMYFKQSPPSTPTTP 157
Query: 574 RGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSL-PTMGQMPGHSSDTSGLSFSQPSCKT 632
P + GA++D A + P L P M +P +G F K
Sbjct: 158 AFPPQ--AGALWDEALPSAPGCIAPG-----PLLDPPMKAVP----TVAGARFPLFHFKP 206
Query: 633 RVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSL-LSAQGVQPTQPTAFEFVRPYSDYL 691
PH P+ A GH+ + Y T SL L A +Q A E PY L
Sbjct: 207 SPPH---PPAPSPAGGHH----LGYDPTAAAALSLPLGAAAAAGSQAAALE-SHPYGLPL 258
Query: 692 NPRSGGIS-SRSGNTDKPRPPPLPSEPPP-PLPP 723
R+ ++ G T P L E P P PP
Sbjct: 259 AKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPP 292
>gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform
c [Homo sapiens]
Length = 443
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 28/214 (13%)
Query: 514 PSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRK 573
PS HHHHH+HH H H H Q +++P P SS + T S+ T
Sbjct: 92 PSYHHHHHHHHHHHHHHQQ-----QHQQPSIPPASSPEDEVLPSTSMYFKQSPPSTPTTP 146
Query: 574 RGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSL-PTMGQMPGHSSDTSGLSFSQPSCKT 632
P + GA++D A + P L P M +P +G F K
Sbjct: 147 AFPPQ--AGALWDEALPSAPGCIAPG-----PLLDPPMKAVP----TVAGARFPLFHFKP 195
Query: 633 RVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSL-LSAQGVQPTQPTAFEFVRPYSDYL 691
PH P+ A GH+ + Y T SL L A +Q A E PY L
Sbjct: 196 SPPH---PPAPSPAGGHH----LGYDPTAAAALSLPLGAAAAAGSQAAALE-SHPYGLPL 247
Query: 692 NPRSGGIS-SRSGNTDKPRPPPLPSEPPP-PLPP 723
R+ ++ G T P L E P P PP
Sbjct: 248 AKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPP 281
>gi|27894357 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 28/214 (13%)
Query: 514 PSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRK 573
PS HHHHH+HH H H H Q +++P P SS + T S+ T
Sbjct: 92 PSYHHHHHHHHHHHHHHQQ-----QHQQPSIPPASSPEDEVLPSTSMYFKQSPPSTPTTP 146
Query: 574 RGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSL-PTMGQMPGHSSDTSGLSFSQPSCKT 632
P + GA++D A + P L P M +P +G F K
Sbjct: 147 AFPPQ--AGALWDEALPSAPGCIAPG-----PLLDPPMKAVP----TVAGARFPLFHFKP 195
Query: 633 RVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSL-LSAQGVQPTQPTAFEFVRPYSDYL 691
PH P+ A GH+ + Y T SL L A +Q A E PY L
Sbjct: 196 SPPH---PPAPSPAGGHH----LGYDPTAAAALSLPLGAAAAAGSQAAALE-SHPYGLPL 247
Query: 692 NPRSGGIS-SRSGNTDKPRPPPLPSEPPP-PLPP 723
R+ ++ G T P L E P P PP
Sbjct: 248 AKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPP 281
>gi|27894355 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 28/214 (13%)
Query: 514 PSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRK 573
PS HHHHH+HH H H H Q +++P P SS + T S+ T
Sbjct: 92 PSYHHHHHHHHHHHHHHQQ-----QHQQPSIPPASSPEDEVLPSTSMYFKQSPPSTPTTP 146
Query: 574 RGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSL-PTMGQMPGHSSDTSGLSFSQPSCKT 632
P + GA++D A + P L P M +P +G F K
Sbjct: 147 AFPPQ--AGALWDEALPSAPGCIAPG-----PLLDPPMKAVP----TVAGARFPLFHFKP 195
Query: 633 RVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSL-LSAQGVQPTQPTAFEFVRPYSDYL 691
PH P+ A GH+ + Y T SL L A +Q A E PY L
Sbjct: 196 SPPH---PPAPSPAGGHH----LGYDPTAAAALSLPLGAAAAAGSQAAALE-SHPYGLPL 247
Query: 692 NPRSGGIS-SRSGNTDKPRPPPLPSEPPP-PLPP 723
R+ ++ G T P L E P P PP
Sbjct: 248 AKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPP 281
>gi|61676093 cyclin C isoform b [Homo sapiens]
Length = 198
Score = 46.6 bits (109), Expect = 8e-05
Identities = 39/169 (23%), Positives = 78/169 (46%), Gaps = 12/169 (7%)
Query: 83 VAPAALFLAAKVEE-QPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIIL 141
+AP +FLA+KVEE +I A + L + S + Y ++ ++ E +L
Sbjct: 1 MAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPY--RMNHILECEFYLL 58
Query: 142 QTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCI 201
+ + L + HP+ +++ Q + +D+ + N + T L Y P ++A C+
Sbjct: 59 ELMDCCLIVYHPYRPLLQYVQDM-GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACL 117
Query: 202 HLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPN 250
H+AC + D + W + + +V +E + E+ L++ E+ N
Sbjct: 118 HVAC------VVQQKDARQW--FAELSVDMEKILEIIRVILKLYEQWKN 158
>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
Length = 908
Score = 45.4 bits (106), Expect = 2e-04
Identities = 47/185 (25%), Positives = 67/185 (36%), Gaps = 35/185 (18%)
Query: 514 PSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRK 573
P +HHHHH+HH H H H P + P H +L S SS SSS +
Sbjct: 335 PPHHHHHHHHHHHHHHHRAQPPQQSHH---PPHHHRPQPHLGSFPESCSSDSESSSYS-- 389
Query: 574 RGPSEETGGAVFDHPAK---IAKSTKSSSLNFSFPSLPTMGQMPGHSSDTSGLSFSQPSC 630
DH A S SSS + S G+ + G S + S
Sbjct: 390 ------------DHAANDSDFGSSLSSSSNSVSSEEEEEEGEEEEEEEEEEGGSGASDSS 437
Query: 631 K--TRVPHSKLDKGPTGANGHNTTQTIDYQDT-----------VNMLHSLLSAQGVQPTQ 677
+ + S + + + + Q+I ++ T N L+ L SA T+
Sbjct: 438 EVSSEEEDSSTESDSSSGSSQVSVQSIRFRRTSFCKPPSVQAQANFLYHLASAAAA--TK 495
Query: 678 PTAFE 682
P AFE
Sbjct: 496 PAAFE 500
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 43.5 bits (101), Expect = 7e-04
Identities = 52/232 (22%), Positives = 87/232 (37%), Gaps = 38/232 (16%)
Query: 502 KSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSL 561
KSR + H S+H S S PV P +SS + L+ K
Sbjct: 354 KSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRL-------PLNSSLGAELSRK---- 402
Query: 562 SSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQMPGHSSDTS 621
+++++ K E G VF P K S ++ LP ++ + DT
Sbjct: 403 KKERAAAAAAAKMDGKESKGSPVF-LPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTE 461
Query: 622 GLSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSLLSAQGVQPTQPTAF 681
++ + + + + N +T + +++ L L AQG + ++P A
Sbjct: 462 LVNVTHLNTEVK-------------NSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIAL 508
Query: 682 EFVRPYSDYLNPRSGGISSRSGNTDKPR----PPPLPSEPPP----PLPPLP 725
+ + + P+ S + P PPPLP+ PP PLPPLP
Sbjct: 509 K-----EEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLP 555
Score = 36.2 bits (82), Expect = 0.11
Identities = 41/163 (25%), Positives = 64/163 (39%), Gaps = 34/163 (20%)
Query: 504 REHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSS 563
RE+ E+ + S+ H H HH H+ S L K K SQ ++ K+ S+
Sbjct: 94 RENDERRGSDRSDRLHKHRHHQHRRSRDLL------KAKQTEKEKSQ--EVSSKSGSMKD 145
Query: 564 SFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQ---MPGH---- 616
S SS R +++ G A++AKS+ S + T + GH
Sbjct: 146 RISGSSK-RSNEETDDYG------KAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRS 198
Query: 617 ------SSDTSGLSFSQPSCKTRVPH------SKLDKGPTGAN 647
+ S + P ++R PH SK D P+GA+
Sbjct: 199 KSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGAS 241
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 43.5 bits (101), Expect = 7e-04
Identities = 52/232 (22%), Positives = 87/232 (37%), Gaps = 38/232 (16%)
Query: 502 KSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSL 561
KSR + H S+H S S PV P +SS + L+ K
Sbjct: 354 KSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRL-------PLNSSLGAELSRK---- 402
Query: 562 SSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQMPGHSSDTS 621
+++++ K E G VF P K S ++ LP ++ + DT
Sbjct: 403 KKERAAAAAAAKMDGKESKGSPVF-LPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTE 461
Query: 622 GLSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSLLSAQGVQPTQPTAF 681
++ + + + + N +T + +++ L L AQG + ++P A
Sbjct: 462 LVNVTHLNTEVK-------------NSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIAL 508
Query: 682 EFVRPYSDYLNPRSGGISSRSGNTDKPR----PPPLPSEPPP----PLPPLP 725
+ + + P+ S + P PPPLP+ PP PLPPLP
Sbjct: 509 K-----EEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLP 555
Score = 36.2 bits (82), Expect = 0.11
Identities = 41/163 (25%), Positives = 64/163 (39%), Gaps = 34/163 (20%)
Query: 504 REHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSS 563
RE+ E+ + S+ H H HH H+ S L K K SQ ++ K+ S+
Sbjct: 94 RENDERRGSDRSDRLHKHRHHQHRRSRDLL------KAKQTEKEKSQ--EVSSKSGSMKD 145
Query: 564 SFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQ---MPGH---- 616
S SS R +++ G A++AKS+ S + T + GH
Sbjct: 146 RISGSSK-RSNEETDDYG------KAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRS 198
Query: 617 ------SSDTSGLSFSQPSCKTRVPH------SKLDKGPTGAN 647
+ S + P ++R PH SK D P+GA+
Sbjct: 199 KSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGAS 241
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 43.1 bits (100), Expect = 0.001
Identities = 69/395 (17%), Positives = 147/395 (37%), Gaps = 47/395 (11%)
Query: 274 TDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTSAVPSLPVSEESSSNLTSVEMLPGKR 333
T + SE ++++ + +S + ++ L TS TS + LP++ E+SS ++S+ +
Sbjct: 685 TSPEISEASLMSNLPLTSEASPVSNLPL--TSETSPMSDLPLTSETSS-VSSMLLTSETT 741
Query: 334 WLSSQP-SFKLEPTQGHRTSENLALTGVDHSLPQDGSNAFISQKQNSKSVPSAKVSLKEY 392
++SS P + P +E +A Q + +S++ S + + K
Sbjct: 742 FVSSLPLPSETSPISNSSINERMA--------HQQRKSPSVSEEPLSPQKDESSATAKPL 793
Query: 393 RAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMPIEGSENPERPFL 452
E L +Q++ L N + + A D H+ + + + + E+P+
Sbjct: 794 ----GENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYP 849
Query: 453 EKADKTALKMRIPVAGGDKAASSK----PEEIKMRIKVHAAADKHNSVEDSVTKSREHKE 508
+ A I V ++ P +++ + +K N + + + +++
Sbjct: 850 ASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYIS 909
Query: 509 KHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSS 568
P + + H + S+L + H+S++S + + + S
Sbjct: 910 SVDKAPFSEGSRNKTHKQGSTQSRL----------ETSHTSKSSEPSKSPDGIRNESRDS 959
Query: 569 SSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQMPGHSSDTSGLSF--- 625
++++ + + G + A+I S+ N S S P Q P L
Sbjct: 960 EISKRKTAEQHSFGICKEKRARI--EDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
Query: 626 ---------SQPSCKTRVPHSKLDKGPTGANGHNT 651
SQP K P S+ + + G NT
Sbjct: 1018 KIGPPFIIKSQPVSK---PESRASTSTSVSGGRNT 1049
Score = 33.1 bits (74), Expect = 0.93
Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
Query: 299 LMSMSTSTTSAVPSLPVSEESSSNLTSVEMLPGKRWLSSQPSFKLEPTQGHRTSENLALT 358
++ ST+ TS++ SL VS ESS ++ P + S QP + + R E +A
Sbjct: 1474 IVDHSTTLTSSL-SLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRP-EPVANE 1531
Query: 359 GVDHSLPQDGSNAFISQKQNSKSVPSAKVSLKE 391
G+DHS ++A KQ+SK++P+ SL+E
Sbjct: 1532 GIDHSSTFIAASA---AKQDSKTLPATCTSLRE 1561
Score = 30.0 bits (66), Expect = 7.9
Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 4/20 (20%)
Query: 708 PRPPPL----PSEPPPPLPP 723
P PPPL P PPPPLPP
Sbjct: 2024 PPPPPLALPPPPPPPPPLPP 2043
>gi|4507347 TBP-associated factor 2 [Homo sapiens]
Length = 1199
Score = 42.7 bits (99), Expect = 0.001
Identities = 46/185 (24%), Positives = 68/185 (36%), Gaps = 58/185 (31%)
Query: 411 EANVKSQYAYAAQNLLSHHDSHSSVILKMPIEGSENPERPFLEK----ADKTALKMRIPV 466
E + + +Q +SHH + E P P L K + ++AL IP
Sbjct: 1043 EEEIDMDTVHDSQAFISHH-----------LNMLERPSTPGLSKYRPASSRSAL---IPQ 1088
Query: 467 --AGGDKAASSKP-------------EEIKMRIKVHAAADKHNSVEDSVTKSREHKEKHK 511
AG D ++KP E+ + + +H AA SV + + +H + H
Sbjct: 1089 HSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHH- 1147
Query: 512 THPSNHHHHHNH------HSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSF 565
HHHHH H H HKH H KH S+ + T+S +S
Sbjct: 1148 -----HHHHHEHKKKKKKHKHKHKHKH-------------KHDSKEKDKEPFTFSSPASG 1189
Query: 566 SSSSS 570
S S
Sbjct: 1190 RSIRS 1194
>gi|134288896 hypothetical protein LOC143684 [Homo sapiens]
Length = 339
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 17/87 (19%)
Query: 494 NSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSN 553
NS S+T+ +H HP +HHHHH+HH H+HS S + + P+
Sbjct: 155 NSSSSSLTEKDQH------HPKHHHHHHHHH-HRHSSSHHKISNLS-----PEEEQGLWK 202
Query: 554 LAHKTYSLSSSFSSSSSTRKRGPSEET 580
+HK SS + + T K+ P E+
Sbjct: 203 QSHK-----SSATIQNETPKKKPKLES 224
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 42.0 bits (97), Expect = 0.002
Identities = 79/443 (17%), Positives = 166/443 (37%), Gaps = 9/443 (2%)
Query: 264 AKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTSAVPSLPVSEESSSNL 323
+ K+++D +D K+ + S +SD++ + S S+ ++ + S S S S+
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 324 TSVEMLPGKRWLSSQPSFKLEPTQGHRTSENLALTGVDHSLPQDGSNAF-ISQKQNSKSV 382
+S SS+ S + + S + + + +S D SN+ S NS
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDS--DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743
Query: 383 PSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMPIE 442
+ S + + + + ++ +++ S + ++ + S + S SS
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDS 803
Query: 443 GSENPERPFLEKADKTALKMRIPVAGGDKAASSKPEEIKMRIKVHAAADKHNSVEDSVTK 502
+ + + +D + D + SS + +D +S +
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863
Query: 503 SREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLS 562
S + + + S+ + S++ S+S + N D SS +S+ + + S
Sbjct: 864 SSDSSDSSDSSNSS-DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922
Query: 563 SSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQMPGHSSDTSG 622
SS SS+SS S+ + + + + S+ SS+ + S S + SSD+S
Sbjct: 923 SSESSNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 623 LSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSLLSAQGVQPTQPTAFE 682
S S S + S +N +++ + D D+ N S S+ + +
Sbjct: 982 SSDSSDSSDS----SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 683 FVRPYSDYLNPRSGGISSRSGNT 705
SD + SS S ++
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDS 1060
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/111 (27%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 623 LSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSLLSAQ----GVQPTQP 678
L QP P++ + P + + T T+ D+ + HS + Q G+ +
Sbjct: 345 LEAKQPDSGMSSPNTTVSVQPLNFDLSSPTSTLSNYDSCSSSHSSIKGQHPPCGLSSARA 404
Query: 679 TAFEFVRPYSDYLNPRSGGISSRSGNTDKPRPPPLPSEPPPP----LPPLP 725
++ Y D LNP G G P PPP PPPP LPP P
Sbjct: 405 AD---IQSYMDMLNPELGLPRGTIGKPTPPPPPPSFPPPPPPPGTQLPPPP 452
Score = 31.2 bits (69), Expect = 3.5
Identities = 13/20 (65%), Positives = 14/20 (70%), Gaps = 2/20 (10%)
Query: 708 PRPPPLP--SEPPPPLPPLP 725
P PPPLP + PPP PPLP
Sbjct: 601 PPPPPLPEAASSPPPAPPLP 620
>gi|61966923 forkhead box B2 [Homo sapiens]
Length = 432
Score = 42.0 bits (97), Expect = 0.002
Identities = 45/183 (24%), Positives = 72/183 (39%), Gaps = 32/183 (17%)
Query: 364 LPQDGSNAFISQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAA- 422
+P+ G +++ QK P + +SL +H+ E + L ++ + ++ Y
Sbjct: 1 MPRPGKSSYSDQKP-----PYSYISLTAMAIQHSAE---KMLPLSDIYKFIMERFPYYRE 52
Query: 423 -----QNLLSHHDSHSSVILKMPIEGSENPERPFLEKADKTALKMRIPVAGGDKAASSKP 477
QN L H+ S + +K+P P++P K AL GD +
Sbjct: 53 HTQRWQNSLRHNLSFNDCFIKIP----RRPDQP--GKGSFWALHPDC----GDMFENGSF 102
Query: 478 EEIKMRIKVHAAADKHNSVEDSVTKSRE------HKEKHKTHPSNHHHHHNHHSHKHSHS 531
+ R KV A H + TKS H H H +HHHHH+ +H H H
Sbjct: 103 LRRRKRFKVLRA--DHTHLHAGSTKSAPGAGPGGHLHPHHHHHPHHHHHHHAAAHHHHHH 160
Query: 532 QLP 534
P
Sbjct: 161 HPP 163
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.125 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,320,002
Number of Sequences: 37866
Number of extensions: 1481791
Number of successful extensions: 17445
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 263
Number of HSP's successfully gapped in prelim test: 270
Number of HSP's that attempted gapping in prelim test: 11616
Number of HSP's gapped (non-prelim): 4081
length of query: 726
length of database: 18,247,518
effective HSP length: 110
effective length of query: 616
effective length of database: 14,082,258
effective search space: 8674670928
effective search space used: 8674670928
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.