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Search of human proteins with 169234951
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169234951 coiled-coil domain containing 17 [Homo sapiens]
(590 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169234951 coiled-coil domain containing 17 [Homo sapiens] 1185 0.0
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 47 5e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 46 8e-05
gi|145386517 phostensin [Homo sapiens] 46 8e-05
gi|199559805 phostensin [Homo sapiens] 46 8e-05
gi|38176300 nestin [Homo sapiens] 45 2e-04
gi|150170670 piccolo isoform 2 [Homo sapiens] 42 0.002
gi|150378539 piccolo isoform 1 [Homo sapiens] 42 0.002
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 41 0.003
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 41 0.003
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 41 0.003
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 41 0.004
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 40 0.005
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 40 0.005
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 40 0.008
gi|33356148 formin-like 1 [Homo sapiens] 39 0.010
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 39 0.013
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 39 0.013
gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo sa... 39 0.013
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 39 0.017
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 39 0.017
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 38 0.023
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 38 0.023
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 38 0.023
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 38 0.023
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 38 0.023
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 38 0.023
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 38 0.023
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 38 0.023
gi|123173757 RAVER1 [Homo sapiens] 38 0.023
>gi|169234951 coiled-coil domain containing 17 [Homo sapiens]
Length = 590
Score = 1185 bits (3065), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MDSHSGEPALLPCGTCDMVFRSSALLATHTQRFCIGHPTQEMTFGAQASVATEPQRAAVQ 60
MDSHSGEPALLPCGTCDMVFRSSALLATHTQRFCIGHPTQEMTFGAQASVATEPQRAAVQ
Sbjct: 1 MDSHSGEPALLPCGTCDMVFRSSALLATHTQRFCIGHPTQEMTFGAQASVATEPQRAAVQ 60
Query: 61 WLRLSLQEMRPWITEVPRVFAGPWTRSEARPQSPMSEAVGSPSERLRALFRTRARRVAEM 120
WLRLSLQEMRPWITEVPRVFAGPWTRSEARPQSPMSEAVGSPSERLRALFRTRARRVAEM
Sbjct: 61 WLRLSLQEMRPWITEVPRVFAGPWTRSEARPQSPMSEAVGSPSERLRALFRTRARRVAEM 120
Query: 121 EAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQ 180
EAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQ
Sbjct: 121 EAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQ 180
Query: 181 ELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQV 240
ELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQV
Sbjct: 181 ELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQV 240
Query: 241 EASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQRGRAPLGPQDLRLLGD 300
EASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQRGRAPLGPQDLRLLGD
Sbjct: 241 EASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQRGRAPLGPQDLRLLGD 300
Query: 301 ASLQPKGRRDPPLLPPPVAPPLPPLPGFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAPY 360
ASLQPKGRRDPPLLPPPVAPPLPPLPGFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAPY
Sbjct: 301 ASLQPKGRRDPPLLPPPVAPPLPPLPGFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAPY 360
Query: 361 DPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRDTGRTTALPPALCLPPPPAPGPMGNC 420
DPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRDTGRTTALPPALCLPPPPAPGPMGNC
Sbjct: 361 DPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRDTGRTTALPPALCLPPPPAPGPMGNC 420
Query: 421 AILASRQPVPRLPPSSSVSLVCELQVWQGLAWARAPQPKAWVSLGLFDQDQRVLSGRWRL 480
AILASRQPVPRLPPSSSVSLVCELQVWQGLAWARAPQPKAWVSLGLFDQDQRVLSGRWRL
Sbjct: 421 AILASRQPVPRLPPSSSVSLVCELQVWQGLAWARAPQPKAWVSLGLFDQDQRVLSGRWRL 480
Query: 481 PLRALPLDPSLSLGQLNGIPQAGQAELFLRLVNARDAAVQTLAEINPASVHEYQYPPPVS 540
PLRALPLDPSLSLGQLNGIPQAGQAELFLRLVNARDAAVQTLAEINPASVHEYQYPPPVS
Sbjct: 481 PLRALPLDPSLSLGQLNGIPQAGQAELFLRLVNARDAAVQTLAEINPASVHEYQYPPPVS 540
Query: 541 STSSLEASFLTPAVGFADPPPRTEEPLSGVKDRDEGLGPHHSSDLPPVSF 590
STSSLEASFLTPAVGFADPPPRTEEPLSGVKDRDEGLGPHHSSDLPPVSF
Sbjct: 541 STSSLEASFLTPAVGFADPPPRTEEPLSGVKDRDEGLGPHHSSDLPPVSF 590
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 47.0 bits (110), Expect = 5e-05
Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 18/194 (9%)
Query: 118 AEMEAQSRALQLRGEELSRRLQVV-----------ACTRGGMSRLFGLEQEIRELQAEAG 166
+ ++A+ L+++G+EL R+L+V+ TRG L + + +LQ
Sbjct: 1030 SRLQAEKSVLEIQGQELHRKLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQLQR--- 1086
Query: 167 RTRGALEVLGARIQELQAEPGNPLSSRREAE-LYSPVQKANPGTLAAEIRAL--REAYIR 223
R LE L R ++L+A + RE + + +Q A E+ L RE ++
Sbjct: 1087 RQEAELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRASVEAQEVALLAERERLMQ 1146
Query: 224 DGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQM 283
DG R G+ ++ +LQ E ++ ++ R R G GE + RLE E L+M
Sbjct: 1147 DGHRQRGLEEELRRLQSEHDRAQMLLAELSRER-GELQGERGELRGRLARLELERAQLEM 1205
Query: 284 QRGRAPLGPQDLRL 297
Q + Q L L
Sbjct: 1206 QSQQLRESNQQLDL 1219
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/236 (26%), Positives = 98/236 (41%), Gaps = 39/236 (16%)
Query: 82 GPWTRSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-------RALQLRGEEL 134
G ++AR + S+ L R A E EAQ+ A++ G+EL
Sbjct: 745 GDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREAEAQAWEQARLREAVEAAGQEL 804
Query: 135 SRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRR 194
Q + L +E R+ + E R R E R+Q L++E L
Sbjct: 805 ESASQEREAL---VEALAAAGRERRQWEREGSRLRAQSEAAEERMQVLESEGRQHLE--- 858
Query: 195 EAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQR----- 249
EAE ++ L AE L +A +R G++ G + Q ++E +ALE Q
Sbjct: 859 EAER----ERREKEALQAE---LEKAVVR--GKELGARLEHLQRELEQAALERQEFLREK 909
Query: 250 -SQTRRGR-----------AGATSGELPVVEAENRRLEAEILALQMQRGRAPLGPQ 293
SQ +R + A ATS E ++E + R L+ E Q+++G A LGP+
Sbjct: 910 ESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLGPK 965
Score = 37.7 bits (86), Expect = 0.030
Identities = 76/291 (26%), Positives = 112/291 (38%), Gaps = 68/291 (23%)
Query: 90 RPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMS 149
RP++P PS L A ++A +AQ R L+ +EL + +++ ++ +
Sbjct: 240 RPEAPSRAPAEGPSHHL-------ALQLANAKAQLRRLR---QELEEKAELLLDSQAEVQ 289
Query: 150 RLFGLEQEIRELQAEAGRTRG-------------ALEVLGARIQELQAEPGNPLSSRREA 196
GLE EIR L+ EA G AL R+ LQ E + A
Sbjct: 290 ---GLEAEIRRLRQEAQALSGQAKRAELYREEAEALRERAGRLPRLQEELRRCRERLQAA 346
Query: 197 ELY----------SPVQKANPGTLAAEIRALRE--AYIRDGGRDPGVL------------ 232
E Y S V +A+ L ++ A RE A + + R+ +L
Sbjct: 347 EAYKSQLEEERVLSGVLEASKALLEEQLEAARERCARLHETQRENLLLRTRLGEAHAELD 406
Query: 233 ---GQIWQLQVEASALELQRSQTRRGRAGA-----TSGELPVVEAENRRLEAEILALQMQ 284
Q+ QL E LEL+ ++ G+ +G P ++ E R EA L +
Sbjct: 407 SLRHQVDQLAEENVELELELQRSLEPPPGSPGEAPLAGAAPSLQDEVREAEAGRLRTLER 466
Query: 285 RGRAPLGPQDLRLLGDASLQPKGRRDPPLLPPPVAPPLPPLPGFSE-PQLP 334
R G LL QP G+ PLL P P+ LP E PQ P
Sbjct: 467 ENRELRG-----LLQVLQGQPGGQH--PLLEAPREDPV--LPVLEEAPQTP 508
Score = 36.6 bits (83), Expect = 0.066
Identities = 51/179 (28%), Positives = 67/179 (37%), Gaps = 37/179 (20%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLF-------GLEQEIRELQAEA 165
RA +A E Q R QL+ + S Q VA RL GLE+E+R LQ+E
Sbjct: 1107 RALELAHRELQGRHEQLQAQRASVEAQEVALL-AERERLMQDGHRQRGLEEELRRLQSEH 1165
Query: 166 GRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDG 225
R + L L ELQ E G EL L + + LRE+
Sbjct: 1166 DRAQMLLAELSRERGELQGERGELRGRLARLEL-------ERAQLEMQSQQLRESN---- 1214
Query: 226 GRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQ 284
QL + A L Q + R+ E ENR+L AE+ AL +
Sbjct: 1215 ----------QQLDLSACRLTTQCELLTQLRSAQ--------EEENRQLLAEVQALSRE 1255
Score = 33.1 bits (74), Expect = 0.73
Identities = 57/207 (27%), Positives = 80/207 (38%), Gaps = 29/207 (14%)
Query: 154 LEQEIRELQAEAGRTRGALE----VLGARIQELQAEPG--NPLSSRREAELYSPVQKANP 207
L+ E+RE AEAGR R LE L +Q LQ +PG +PL + PV + P
Sbjct: 449 LQDEVRE--AEAGRLR-TLERENRELRGLLQVLQGQPGGQHPLLEAPREDPVLPVLEEAP 505
Query: 208 GTLAAEIRALREAY--IRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELP 265
T A + + RDGG L + AL+ A A + P
Sbjct: 506 QTPVAFDHSPQGLVQKARDGGPQA--------LDLAPPALDSVLE------ASAECPQAP 551
Query: 266 VVEAENRRLEAEILALQMQRGRAPLGPQDLRLLGDASLQPK--GRRDPPLLPPPVAPPLP 323
+++ + E+ + A M + PQ+ + P+ GRR P VAPP
Sbjct: 552 --DSDPQEAESPLQAAAMDPQASDWSPQESGSPVETQESPEKAGRRSSLQSPASVAPPQG 609
Query: 324 PLPGFSEPQLPGTMTRNLGLDSHFLLP 350
P PQL G T L+P
Sbjct: 610 PGTKIQAPQLLGGETEGREAPQGELVP 636
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 46.2 bits (108), Expect = 8e-05
Identities = 76/291 (26%), Positives = 108/291 (37%), Gaps = 33/291 (11%)
Query: 311 PPLLPPPVAPPLPPLPGFS--EPQLPGTMTRNLGLDSHFLLPTSDMLGPAPYDPGAGLVI 368
PPL PP P PPL + PQ P + +L L + F P S + AP+ P A +
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPV-QAPFSPPASPPV 685
Query: 369 FYDFLRGLEA--SWIWVQLRTGLARDGRDTGRTTALPPALCLPP---PP---APGPMGNC 420
+A S L+ + +A PP PP PP P P +
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
Query: 421 AILASRQPVPRLPPSSSVSLVCELQVWQGLAWARAPQPKAWVSLG-LFDQDQRVLSGRWR 479
+ S P PR+PP + LQV P P A + + L +
Sbjct: 746 PMSPSATPPPRVPPLLAAP---PLQV--------PPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 480 LPLRALPLDPSLSLGQLNGIPQAG--QAELFLRLVNARDAAVQTLAEINPA-----SVHE 532
PL+ALP P+ GQ P A + L A L ++ P+ ++
Sbjct: 795 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854
Query: 533 YQYPPPVSSTSSLEASFLTPAVGFADPPPRTEEPLSGVKDRDEGLGPHHSS 583
+ PP +S+ LT A+ PPP + P S + D L H SS
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD--LAGHSSS 903
>gi|145386517 phostensin [Homo sapiens]
Length = 613
Score = 46.2 bits (108), Expect = 8e-05
Identities = 64/259 (24%), Positives = 93/259 (35%), Gaps = 33/259 (12%)
Query: 100 GSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIR 159
G ER L +R + E +SR GE ++L + + EQ +
Sbjct: 197 GETPERSLRLAESREQSPRRKEVESRLSP--GESAYQKLGLTEAHKWRPDSRESQEQSLV 254
Query: 160 ELQAEAGRTRGALEVLGARIQELQAEPGNP-------LSSRREAELYSPVQKANPGTLAA 212
+L+A R R G Q+ E G ++ + AEL + + G +A
Sbjct: 255 QLEATEWRLRS-----GEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSA 309
Query: 213 EIRALREAYIRDGGRD-PGVLGQIWQLQVEASA------LELQRSQTRRGRAGATSGELP 265
+ A + + DG R G W L + +E Q + + E P
Sbjct: 310 GVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESP 369
Query: 266 VVEAENRRLEAEILALQMQRGRA---------PLGPQDLRLLGDASLQPKGRRDPPLLPP 316
VEA E E Q + RA PL P+D G L+ + L PP
Sbjct: 370 GVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDA---GTGGLRQQEEEAVELQPP 426
Query: 317 PVAPPLPPLPGFSEPQLPG 335
P AP PP P + PQ PG
Sbjct: 427 PPAPLSPPPPAPTAPQPPG 445
>gi|199559805 phostensin [Homo sapiens]
Length = 613
Score = 46.2 bits (108), Expect = 8e-05
Identities = 64/259 (24%), Positives = 93/259 (35%), Gaps = 33/259 (12%)
Query: 100 GSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIR 159
G ER L +R + E +SR GE ++L + + EQ +
Sbjct: 197 GETPERSLRLAESREQSPRRKEVESRLSP--GESAYQKLGLTEAHKWRPDSRESQEQSLV 254
Query: 160 ELQAEAGRTRGALEVLGARIQELQAEPGNP-------LSSRREAELYSPVQKANPGTLAA 212
+L+A R R G Q+ E G ++ + AEL + + G +A
Sbjct: 255 QLEATEWRLRS-----GEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSA 309
Query: 213 EIRALREAYIRDGGRD-PGVLGQIWQLQVEASA------LELQRSQTRRGRAGATSGELP 265
+ A + + DG R G W L + +E Q + + E P
Sbjct: 310 GVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESP 369
Query: 266 VVEAENRRLEAEILALQMQRGRA---------PLGPQDLRLLGDASLQPKGRRDPPLLPP 316
VEA E E Q + RA PL P+D G L+ + L PP
Sbjct: 370 GVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDA---GTGGLRQQEEEAVELQPP 426
Query: 317 PVAPPLPPLPGFSEPQLPG 335
P AP PP P + PQ PG
Sbjct: 427 PPAPLSPPPPAPTAPQPPG 445
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 45.1 bits (105), Expect = 2e-04
Identities = 72/293 (24%), Positives = 107/293 (36%), Gaps = 29/293 (9%)
Query: 132 EELSRRLQVV--ACTRGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNP 189
EEL+RRL RG R+ +E + + + GR +Q+LQAE G
Sbjct: 176 EELARRLGEAWRGAVRGYQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGL 235
Query: 190 LSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQR 249
L R + +++ G +RA + + + L+ E L+ Q
Sbjct: 236 LERR------AALEQRLEGRWQERLRATEKFQL-----------AVEALEQEKQGLQSQI 278
Query: 250 SQTRRGRAGATSGELPV---VEAENRRLEAEILALQMQRG--RAPLGPQDLRLLGDASLQ 304
+Q GR ++ + V LEAE LQ G + L QD +L
Sbjct: 279 AQVLEGRQQLAHLKMSLSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQDPKLELQFPRT 338
Query: 305 PKGRRDPPLLPPPVAPPLP-PLPGFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAPYDPG 363
P+GRR LLP LP PLP E +P + L + S + P P P
Sbjct: 339 PEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQARTPTLASTPIPPTPQAPS 398
Query: 364 AGLVIFYDFLRGLEASWIWVQLRTGLARDGRD-TGRTTALPPALCLPPPPAPG 415
+ +R +A +Q + G + PA LP P PG
Sbjct: 399 PAVDA---EIRAQDAPLSLLQTQGGRKQAPEPLRAEARVAIPASVLPGPEEPG 448
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 30/192 (15%)
Query: 300 DASLQPKGRRDPPLLPPPVAPPLPPLPGFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAP 359
D S QP PP PPP PP PP P P P +LP + +P
Sbjct: 2400 DISAQPPPPPPPPPPPPPPPPP-PPPPPLPPPTSP----------KPTILPKKKLTVASP 2448
Query: 360 YDPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRDTGR--TTALPPALCLPPPPAPGPM 417
L +D + LE + + L +G R TTA PP +PP P+ P
Sbjct: 2449 VTTATPL---FDAVTTLETTAV-------LRSNGLPVTRICTTAPPP---VPPKPSSIPS 2495
Query: 418 GNCAILASRQPVPRLPPSSSVSLVCELQVWQGLAWARAPQPKAWVSLGLFDQDQRVLSGR 477
G ++ + +P P PP + ++ +L P+P +SL V S
Sbjct: 2496 G---LVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG-LSLTSSMTLNLVTSAD 2551
Query: 478 WRLPLRALPLDP 489
++LP PL P
Sbjct: 2552 YKLPSPTSPLSP 2563
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 30/192 (15%)
Query: 300 DASLQPKGRRDPPLLPPPVAPPLPPLPGFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAP 359
D S QP PP PPP PP PP P P P +LP + +P
Sbjct: 2400 DISAQPPPPPPPPPPPPPPPPP-PPPPPLPPPTSP----------KPTILPKKKLTVASP 2448
Query: 360 YDPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRDTGR--TTALPPALCLPPPPAPGPM 417
L +D + LE + + L +G R TTA PP +PP P+ P
Sbjct: 2449 VTTATPL---FDAVTTLETTAV-------LRSNGLPVTRICTTAPPP---VPPKPSSIPS 2495
Query: 418 GNCAILASRQPVPRLPPSSSVSLVCELQVWQGLAWARAPQPKAWVSLGLFDQDQRVLSGR 477
G ++ + +P P PP + ++ +L P+P +SL V S
Sbjct: 2496 G---LVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG-LSLTSSMTLNLVTSAD 2551
Query: 478 WRLPLRALPLDP 489
++LP PL P
Sbjct: 2552 YKLPSPTSPLSP 2563
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 41.2 bits (95), Expect = 0.003
Identities = 47/171 (27%), Positives = 65/171 (38%), Gaps = 20/171 (11%)
Query: 303 LQPKGRRDPPLLPPPVAPPLPPLPGFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAPYDP 362
L P+G R P L PP + PLPP S P T++ D + P + P P
Sbjct: 784 LSPQGSRTPSPLVPPGSSPLPPRLS-SSPGKTMPTTQSFASDPKYATP-QVIQAPGPRAG 841
Query: 363 GAGLVIFYDFLRGLEASWIWVQLRTG-------LARDGRDTGRTTALPPALCLPPPPAPG 415
L I D + + + R R+ + T LP L LPPP P
Sbjct: 842 PCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPA 901
Query: 416 PMGNCAILASRQPVPR--LPPSSSVSLVCELQVWQGLAWARAPQPKAWVSL 464
P A A+ +P+P+ L P ++ S AR P P+A L
Sbjct: 902 P---AAPTATVRPMPQAALDPKANFS------TNNSNPGARPPPPRATARL 943
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens]
Length = 1086
Score = 41.2 bits (95), Expect = 0.003
Identities = 47/171 (27%), Positives = 65/171 (38%), Gaps = 20/171 (11%)
Query: 303 LQPKGRRDPPLLPPPVAPPLPPLPGFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAPYDP 362
L P+G R P L PP + PLPP S P T++ D + P + P P
Sbjct: 862 LSPQGSRTPSPLVPPGSSPLPPRLS-SSPGKTMPTTQSFASDPKYATP-QVIQAPGPRAG 919
Query: 363 GAGLVIFYDFLRGLEASWIWVQLRTG-------LARDGRDTGRTTALPPALCLPPPPAPG 415
L I D + + + R R+ + T LP L LPPP P
Sbjct: 920 PCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPA 979
Query: 416 PMGNCAILASRQPVPR--LPPSSSVSLVCELQVWQGLAWARAPQPKAWVSL 464
P A A+ +P+P+ L P ++ S AR P P+A L
Sbjct: 980 P---AAPTATVRPMPQAALDPKANFS------TNNSNPGARPPPPRATARL 1021
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 41.2 bits (95), Expect = 0.003
Identities = 56/216 (25%), Positives = 83/216 (38%), Gaps = 34/216 (15%)
Query: 104 ERLRALFRTRARRVAEMEAQSRALQLRGEEL---SRRLQVVACTRGGMS-RLFGLEQEIR 159
E+L L R + R E+E R Q + E L +R + +A G++ +L E+E R
Sbjct: 834 EQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGR 893
Query: 160 ELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALRE 219
L EA R R E L + E+Q + + R + E TL E+ LR+
Sbjct: 894 TLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQ 953
Query: 220 AYI---RDGGRDPGVLGQ-----------------------IWQLQVEASA----LELQR 249
I D ++ Q + +LQ E A LE +R
Sbjct: 954 QIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAER 1013
Query: 250 SQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
+Q + L +EAE L EI ALQ +R
Sbjct: 1014 AQLQSQLQREQEELLARLEAEKEELSEEIAALQQER 1049
Score = 33.9 bits (76), Expect = 0.43
Identities = 46/173 (26%), Positives = 78/173 (45%), Gaps = 22/173 (12%)
Query: 156 QEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL----YSPVQKANPGTLA 211
QE+R Q E R L ++ E++AE + S R+ + +++ G L+
Sbjct: 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1575
Query: 212 ---AEIRALREAYIRDGGRD-PGVLGQIWQLQ--VEASALELQRSQTRRGRAGATSGELP 265
AE+ AL+E +R R+ L Q+ L+ ++A+ EL+ SQ + + A +L
Sbjct: 1576 GVQAEL-ALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKL- 1633
Query: 266 VVEAENRRL-------EAEILALQMQRGRAPLGPQDLRL-LGDASLQPKGRRD 310
E + RRL E+ + L++QR Q RL L D Q + +D
Sbjct: 1634 --EGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQD 1684
Score = 32.3 bits (72), Expect = 1.3
Identities = 48/181 (26%), Positives = 76/181 (41%), Gaps = 37/181 (20%)
Query: 115 RRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGALEV 174
R +AE++ + AL R E+ SRR GL Q + + +A R L+V
Sbjct: 1301 RELAELQGRL-ALGERAEKESRR------------ETLGLRQRLLKGEASLEVMRQELQV 1347
Query: 175 LGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQ 234
++QE + E RE L +++A GT ++ R G+ +
Sbjct: 1348 AQRKLQEQEGE-----FRTRERRLLGSLEEAR-GTEKQQLDHAR-----------GLELK 1390
Query: 235 IWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQ------MQRGRA 288
+ + EA+ L L+ S GRA EL VE + R EA++ L+ + GRA
Sbjct: 1391 LEAARAEAAELGLRLSAAE-GRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRA 1449
Query: 289 P 289
P
Sbjct: 1450 P 1450
Score = 32.3 bits (72), Expect = 1.3
Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 28/178 (15%)
Query: 117 VAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGALEVLG 176
+++ EAQ++ALQ R + L R+ VA + L + + A+ + GAL
Sbjct: 1672 LSDREAQAQALQDRVDSLQRQ---VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1728
Query: 177 ARIQELQAEPGNPLSSRREAELYSPVQKA------NPGTLAAEIRALREAYIRDGGRDPG 230
+ E A+ L+S R+ L+ +QKA + L + A R+A +
Sbjct: 1729 RGLTEALAQSSASLNSTRDKNLH--LQKALTACEHDRQVLQERLDAARQALSEARKQSSS 1786
Query: 231 VLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQRGRA 288
+ Q+ L+ E + LELQR VEAE + + + Q Q G A
Sbjct: 1787 LGEQVQTLRGEVADLELQR-----------------VEAEGQLQQLREVLRQRQEGEA 1827
Score = 30.8 bits (68), Expect = 3.6
Identities = 47/187 (25%), Positives = 81/187 (43%), Gaps = 26/187 (13%)
Query: 104 ERLRALFRTRARRVAEMEAQSRALQLRGEELSRRL-QVVACTRGGMSRLFGLEQEIRELQ 162
+ LR R++AEMEA+ + R +L + + + R RL G++ E+ LQ
Sbjct: 1526 DELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAEL-ALQ 1584
Query: 163 AEAGR-----TRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRAL 217
E+ R R L+ + + LQA S R ++ KAN L + R L
Sbjct: 1585 EESVRRSERERRATLDQVATLERSLQATE----SELRASQEKISKMKANETKLEGDKRRL 1640
Query: 218 REAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAE 277
+E + D V +L+++ +LE + ++R G L EA+ + L+
Sbjct: 1641 KE--VLDASESRTV-----KLELQRRSLEGELQRSRLG--------LSDREAQAQALQDR 1685
Query: 278 ILALQMQ 284
+ +LQ Q
Sbjct: 1686 VDSLQRQ 1692
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 40.8 bits (94), Expect = 0.004
Identities = 48/177 (27%), Positives = 82/177 (46%), Gaps = 20/177 (11%)
Query: 86 RSEARPQSPMSEAVGSPSERL-------RALFRTRARRVAEM----EAQSRALQLRGEEL 134
+SE S +S +V +RL R + R R+R+ +E+ + + + L L E L
Sbjct: 580 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 639
Query: 135 SRRLQVVACTRGGMSRLFG----LEQEIRELQAEAGRTRGALEVLGARIQELQA-EPGNP 189
+RLQ + G + + LEQ+ R Q +A LE + +I + +A E G
Sbjct: 640 KKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEV 699
Query: 190 LSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALE 246
+S E +++A L AE++AL+E ++ Q+ QLQV+ S L+
Sbjct: 700 VSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKE----DQLSQLQVDYSVLQ 752
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 40.4 bits (93), Expect = 0.005
Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 16/84 (19%)
Query: 260 TSGELPVVEAENRRLEAEILALQMQRG------RAPLGPQDLRLLGDASLQPKGRRDPPL 313
T EL EA+ L+AE+ A + Q G PL P G ++L P PPL
Sbjct: 263 TQAELQKKEAKINELQAELQAFKSQFGALPADCNIPLPPSKEGGTGHSALPPP----PPL 318
Query: 314 L------PPPVAPPLPPLPGFSEP 331
PPP PP PPLPG P
Sbjct: 319 PSGGGVPPPPPPPPPPPLPGMRMP 342
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 40.4 bits (93), Expect = 0.005
Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 16/84 (19%)
Query: 260 TSGELPVVEAENRRLEAEILALQMQRG------RAPLGPQDLRLLGDASLQPKGRRDPPL 313
T EL EA+ L+AE+ A + Q G PL P G ++L P PPL
Sbjct: 526 TQAELQKKEAKINELQAELQAFKSQFGALPADCNIPLPPSKEGGTGHSALPPP----PPL 581
Query: 314 L------PPPVAPPLPPLPGFSEP 331
PPP PP PPLPG P
Sbjct: 582 PSGGGVPPPPPPPPPPPLPGMRMP 605
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 39.7 bits (91), Expect = 0.008
Identities = 66/228 (28%), Positives = 90/228 (39%), Gaps = 32/228 (14%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGM 148
A+ Q + E E L RA R A +E Q EELS RL+ GG
Sbjct: 1151 AQMQKKIKELQARAEELEEELEAERAAR-ARVEKQRAEAARELEELSERLEEA----GGA 1205
Query: 149 SRLFGLEQEIRELQAEAGRTRGALEVLGARIQ-----------ELQAEPGNPLSS----R 193
S G + R+ +AE GR R LE R + E AE G + S R
Sbjct: 1206 SA--GQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVR 1263
Query: 194 REAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQ-- 251
++ E + LAA + L A Q+ + +++ L+ Q +
Sbjct: 1264 QKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADAS 1323
Query: 252 TRRGRAGATSGELPVVEAENRRL-EAEILALQMQRGRAPLGPQDLRLL 298
T+RGR SGEL +R L E E L Q+ RG+A L Q L L
Sbjct: 1324 TQRGRLQTESGEL------SRLLEEKECLISQLSRGKA-LAAQSLEEL 1364
Score = 34.7 bits (78), Expect = 0.25
Identities = 44/187 (23%), Positives = 77/187 (41%), Gaps = 18/187 (9%)
Query: 115 RRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGL-EQEIRELQAEAGRTRGALE 173
R++A+ Q LQ ELSR L+ C +SR L Q + EL+ + A
Sbjct: 1317 RQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKS 1376
Query: 174 VLGARIQELQAE-----PGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
L +Q L+ + + + +AEL + KAN AE+ R Y D
Sbjct: 1377 ALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKAN-----AEVAQWRSKYEAD---- 1427
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENR-RLEAEILALQMQRGR 287
+ + +L+ L L+ + G A + + +A+ R + E+E + L+++R
Sbjct: 1428 --AIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERAT 1485
Query: 288 APLGPQD 294
+ D
Sbjct: 1486 SAAAALD 1492
Score = 31.6 bits (70), Expect = 2.1
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 118 AEMEAQSRALQLRGEELSRRLQVV--ACTRGGMSRLFGLEQEIRELQAE--AGRTRGALE 173
A +E + L+ EL RL+ A RGG ++ LE ++REL+AE A + + A
Sbjct: 1826 AHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEA 1885
Query: 174 VLGARIQE 181
+ G R E
Sbjct: 1886 LKGVRKHE 1893
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 39.3 bits (90), Expect = 0.010
Identities = 51/182 (28%), Positives = 65/182 (35%), Gaps = 21/182 (11%)
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRR--EAELYSPVQKANPGTLAAEI 214
+I EL+ + + R LE L R E A +SRR E E P P L ++
Sbjct: 425 KIAELEKQLSQARKELETLRERFSESTAMG----ASRRPPEPEKAPPAAPTRPSALELKV 480
Query: 215 RALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRL 274
L E + R PG I L V + + T G+ S +L
Sbjct: 481 EELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAP-------- 532
Query: 275 EAEILALQMQRGRAPLGPQDLRLLGDASLQPKGR--RDPPLLPPPVAPPLPPLPGFSEPQ 332
A + G AP P L L P + PPL P PP PPLPG P
Sbjct: 533 -----AAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPP 587
Query: 333 LP 334
P
Sbjct: 588 PP 589
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 38.9 bits (89), Expect = 0.013
Identities = 57/209 (27%), Positives = 74/209 (35%), Gaps = 25/209 (11%)
Query: 237 QLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQ-RGRAPLGPQDL 295
Q+ E LE + SQ G + EL + E L A + + RAP+ P
Sbjct: 520 QIATEKQDLEAEVSQLT-GEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAP- 577
Query: 296 RLLGDASL-----QPKGRRDPPLLPPPVAPPLPPLPG----FSEPQLPG--TMTRNLGLD 344
L GD+ G P PPP PP PPLPG S P LPG ++ L
Sbjct: 578 PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLS 637
Query: 345 SHFLLPTSDMLGPAPYDPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRDTGRTTALPP 404
+P P P G G+ G + L R LP
Sbjct: 638 GDATIPP-----PPPLPEGVGIPSPSSLPGGTA-----IPPPPPLPGSARIPPPPPPLPG 687
Query: 405 ALCLPPPPAPGPMGNCAILASRQPVPRLP 433
+ +PPPP P P G + P+P P
Sbjct: 688 SAGIPPPPPPLP-GEAGMPPPPPPLPGGP 715
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 38.9 bits (89), Expect = 0.013
Identities = 57/209 (27%), Positives = 74/209 (35%), Gaps = 25/209 (11%)
Query: 237 QLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQ-RGRAPLGPQDL 295
Q+ E LE + SQ G + EL + E L A + + RAP+ P
Sbjct: 529 QIATEKQDLEAEVSQLT-GEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAP- 586
Query: 296 RLLGDASL-----QPKGRRDPPLLPPPVAPPLPPLPG----FSEPQLPG--TMTRNLGLD 344
L GD+ G P PPP PP PPLPG S P LPG ++ L
Sbjct: 587 PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLS 646
Query: 345 SHFLLPTSDMLGPAPYDPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRDTGRTTALPP 404
+P P P G G+ G + L R LP
Sbjct: 647 GDATIPP-----PPPLPEGVGIPSPSSLPGGTA-----IPPPPPLPGSARIPPPPPPLPG 696
Query: 405 ALCLPPPPAPGPMGNCAILASRQPVPRLP 433
+ +PPPP P P G + P+P P
Sbjct: 697 SAGIPPPPPPLP-GEAGMPPPPPPLPGGP 724
>gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo
sapiens]
Length = 669
Score = 38.9 bits (89), Expect = 0.013
Identities = 58/202 (28%), Positives = 77/202 (38%), Gaps = 53/202 (26%)
Query: 115 RRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEA--------- 165
RR A +E + R L R EE + C + G L L+Q+++E QAE
Sbjct: 420 RRCATLEREQRELGPRLEETKWEV----CQKSGEISL--LKQQLKESQAELVQKGSELVA 473
Query: 166 ----------------GRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGT 209
GR RG E AR EL+A R+EAE + G
Sbjct: 474 LRVALREARATLRVSEGRARGLQEAARARELELEACSQELQRHRQEAEQL----REKAGQ 529
Query: 210 LAAEIRALREAYIRDGGRDPGVL---------------GQIWQLQVEASALELQRSQTRR 254
L AE LRE + DP +L G + QVE +ELQR + RR
Sbjct: 530 LDAEAAGLREPPVPPATADPFLLAESDEAKVQRAAAGVGGSLRAQVERLRVELQR-ERRR 588
Query: 255 GRAGATS--GELPVVEAENRRL 274
G S GE +AE ++
Sbjct: 589 GEEQRDSFEGERLAWQAEKEQV 610
Score = 32.0 bits (71), Expect = 1.6
Identities = 46/175 (26%), Positives = 70/175 (40%), Gaps = 21/175 (12%)
Query: 150 RLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGT 209
++F L+QE R+LQ + + E L R L+ E L R E + QK+ G
Sbjct: 393 QVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQ-RELGPRLEETKWEVCQKS--GE 449
Query: 210 LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTR---RGRAGATSGELPV 266
++ + L+E+ ++ Q E AL + + R R G G
Sbjct: 450 ISLLKQQLKESQ-----------AELVQKGSELVALRVALREARATLRVSEGRARGLQEA 498
Query: 267 VEAENRRLEAEILALQMQRGRAPLGPQDLRLLGDASLQPKGRRDPPLLPPPVAPP 321
A R LE E + ++QR R Q G + G R+PP +PP A P
Sbjct: 499 ARA--RELELEACSQELQRHRQE-AEQLREKAGQLDAEAAGLREPP-VPPATADP 549
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 38.5 bits (88), Expect = 0.017
Identities = 48/204 (23%), Positives = 79/204 (38%), Gaps = 12/204 (5%)
Query: 118 AEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGL-EQEIRELQAEAGRTRGALEVLG 176
A ++A R + G EL R + ++G G E+E+ L E GR + L +
Sbjct: 965 AALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEK 1024
Query: 177 ARIQELQAEPGNPLSSRR-------EAELYSPVQKANPGTLAAEIRALREAYIRDGGRDP 229
A EL+ N L+ +R EA ++ +K A++R L A I++
Sbjct: 1025 AARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELR 1084
Query: 230 GVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQRGRAP 289
+ Q+ + + S + AG T P +EA L AE+ L+ Q +
Sbjct: 1085 QTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEA----LRAEVSKLEQQCQKQQ 1140
Query: 290 LGPQDLRLLGDASLQPKGRRDPPL 313
L +A + RD L
Sbjct: 1141 EQADSLERSLEAERASRAERDSAL 1164
Score = 33.1 bits (74), Expect = 0.73
Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 25/186 (13%)
Query: 116 RVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGALEVL 175
+V ++E R + EELS++L S++ +Q+++ +QA+ G ++ + L
Sbjct: 1536 QVEQLEVFQREQTKQVEELSKKL----ADSDQASKV--QQQKLKAVQAQGGESQQEAQRL 1589
Query: 176 GARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQI 235
A++ ELQA+ + +L K + + + L+E L +
Sbjct: 1590 QAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQ-----------LRSL 1638
Query: 236 WQLQVEASALELQRSQTRRGRAGATSGELPVVEAEN--RRLEAEILALQMQRGRAPLGPQ 293
QLQ E EL+ R G +G L EAE R L A++ +L+ Q A Q
Sbjct: 1639 EQLQKENK--ELRAEAERLGHELQQAG-LKTKEAEQTCRHLTAQVRSLEAQVAHA---DQ 1692
Query: 294 DLRLLG 299
LR LG
Sbjct: 1693 QLRDLG 1698
Score = 30.8 bits (68), Expect = 3.6
Identities = 40/184 (21%), Positives = 74/184 (40%), Gaps = 15/184 (8%)
Query: 46 AQASVATEPQRAAVQWLRLSLQEMRPWITEVPRVFAGPWTRSEARPQSPMSEAVGSPSER 105
AQ + + Q A Q LR ++++ + + + + EA Q + + ER
Sbjct: 533 AQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEER 592
Query: 106 LRALFRTRARRVAEMEAQSRALQLRGEELSRRLQVVACTR-GGMSRLFGLEQEIRELQAE 164
A R R + ++EA + + E L ++LQV R + + ++E EL +
Sbjct: 593 -EASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRK 651
Query: 165 AGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKA--------NPGTLAAEIRA 216
+ +E E QA+ + E +L S QKA L +++A
Sbjct: 652 VEELQACVETARQEQHEAQAQ-----VAELELQLRSEQQKATEKERVAQEKDQLQEQLQA 706
Query: 217 LREA 220
L+E+
Sbjct: 707 LKES 710
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 38.5 bits (88), Expect = 0.017
Identities = 46/192 (23%), Positives = 85/192 (44%), Gaps = 26/192 (13%)
Query: 105 RLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAE 164
RL R + ++A+ME +++ L+ EEL + + ++ R LE + + AE
Sbjct: 711 RLVETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSER---LELSYQSVSAE 767
Query: 165 AGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALR--EAYI 222
R + +LE + Q L++E G L + R+A L ++ ALR A +
Sbjct: 768 NLRLQQSLESSSHKTQTLESELGE-LEAERQA-------------LRRDLEALRLANAQL 813
Query: 223 RDGGRDPGVLGQ-IWQLQVEASALE------LQRSQTRRGRAGATSGELPVVEAENRRLE 275
+D L Q + QL+ + LE Q+ + + ++ +L VE E+R L+
Sbjct: 814 EGAEKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALD 873
Query: 276 AEILALQMQRGR 287
E+ + G+
Sbjct: 874 KELARCRDAAGK 885
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/197 (23%), Positives = 82/197 (41%), Gaps = 14/197 (7%)
Query: 86 RSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-RALQLRGEELSRRLQVVACT 144
R +A + + +E+ + ARR + E Q+ R +L +EL ++ Q+
Sbjct: 1645 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLA--- 1701
Query: 145 RGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL-YSPVQ 203
G + EQE+ L+AE + ++L + LQ E R+E E + V+
Sbjct: 1702 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1761
Query: 204 KANPGTLAAEIRALREAYI---RDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260
LA++ RA E+ + R G+ +L EA+ L + +R R
Sbjct: 1762 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---- 1817
Query: 261 SGELPVVEAENRRLEAE 277
+L +A +R EAE
Sbjct: 1818 --QLAEEDAARQRAEAE 1832
Score = 32.0 bits (71), Expect = 1.6
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 42/210 (20%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRR-LQVVACTRGG 147
AR +S + E + S ++ L + +AR +EA++RAL LR ++ ++R LQ A
Sbjct: 2220 ARQRSQVEEELFSVRVQMEELSKLKAR----IEAENRALILRDKDNTQRFLQEEA----- 2270
Query: 148 MSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANP 207
++++++ EA R A + AR+++L E + E L +Q
Sbjct: 2271 --------EKMKQVAEEAARLSVAAQE-AARLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2321
Query: 208 GT-LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPV 266
T L AE L++ Q Q +A L+ + Q + A T G
Sbjct: 2322 ATRLKAEAELLQQ--------------QKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2367
Query: 267 VEAENRR-----LEAEILAL---QMQRGRA 288
+EAE +R EAE L L +M R +A
Sbjct: 2368 LEAERQRQLEMSAEAERLKLRVAEMSRAQA 2397
Score = 30.8 bits (68), Expect = 3.6
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Query: 103 SERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQ------VVACTRGGMSRLFGLEQ 156
+ERLR R +++ +++ LQL+ EE+ Q A + +S L Q
Sbjct: 2445 AERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ 2504
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRA 216
R ++ E + + A+ Q+L+ E R++ ++ Q+ + +
Sbjct: 2505 RERFIEQEKAKLEQLFQDEVAKAQQLREE-----QQRQQQQMEQERQRL--------VAS 2551
Query: 217 LREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEA 276
+ EA R + GV + Q E LE QR Q ++ EN+RL
Sbjct: 2552 MEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEE-----------LLAEENQRLRE 2596
Query: 277 EILALQMQRGRA 288
++ L+ Q A
Sbjct: 2597 QLQLLEEQHRAA 2608
Score = 29.6 bits (65), Expect = 8.1
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGA- 171
R++ AE+EA +R QL EE RR R R+ Q+ + EA R R A
Sbjct: 1960 RSKEQAELEA-ARQRQLAAEEERRR-------REAEERV----QKSLAAEEEAARQRKAA 2007
Query: 172 ---LEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
+E L A+++E + L R E E +Q A ++A +A+ +
Sbjct: 2008 LEEVERLKAKVEEARR-----LRERAEQESARQLQLAQEAA-QKRLQAEEKAHAFAVQQK 2061
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
L Q LQ E S L+ R + R A EAE R++AE A Q +R
Sbjct: 2062 EQELQQT--LQQEQSVLDQLRGEAEAARRAAE-------EAEEARVQAEREAAQSRR 2109
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/197 (23%), Positives = 82/197 (41%), Gaps = 14/197 (7%)
Query: 86 RSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-RALQLRGEELSRRLQVVACT 144
R +A + + +E+ + ARR + E Q+ R +L +EL ++ Q+
Sbjct: 1649 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLA--- 1705
Query: 145 RGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL-YSPVQ 203
G + EQE+ L+AE + ++L + LQ E R+E E + V+
Sbjct: 1706 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1765
Query: 204 KANPGTLAAEIRALREAYI---RDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260
LA++ RA E+ + R G+ +L EA+ L + +R R
Sbjct: 1766 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---- 1821
Query: 261 SGELPVVEAENRRLEAE 277
+L +A +R EAE
Sbjct: 1822 --QLAEEDAARQRAEAE 1836
Score = 32.0 bits (71), Expect = 1.6
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 42/210 (20%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRR-LQVVACTRGG 147
AR +S + E + S ++ L + +AR +EA++RAL LR ++ ++R LQ A
Sbjct: 2224 ARQRSQVEEELFSVRVQMEELSKLKAR----IEAENRALILRDKDNTQRFLQEEA----- 2274
Query: 148 MSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANP 207
++++++ EA R A + AR+++L E + E L +Q
Sbjct: 2275 --------EKMKQVAEEAARLSVAAQE-AARLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2325
Query: 208 GT-LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPV 266
T L AE L++ Q Q +A L+ + Q + A T G
Sbjct: 2326 ATRLKAEAELLQQ--------------QKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2371
Query: 267 VEAENRR-----LEAEILAL---QMQRGRA 288
+EAE +R EAE L L +M R +A
Sbjct: 2372 LEAERQRQLEMSAEAERLKLRVAEMSRAQA 2401
Score = 30.8 bits (68), Expect = 3.6
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Query: 103 SERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQ------VVACTRGGMSRLFGLEQ 156
+ERLR R +++ +++ LQL+ EE+ Q A + +S L Q
Sbjct: 2449 AERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ 2508
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRA 216
R ++ E + + A+ Q+L+ E R++ ++ Q+ + +
Sbjct: 2509 RERFIEQEKAKLEQLFQDEVAKAQQLREE-----QQRQQQQMEQERQRL--------VAS 2555
Query: 217 LREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEA 276
+ EA R + GV + Q E LE QR Q ++ EN+RL
Sbjct: 2556 MEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEE-----------LLAEENQRLRE 2600
Query: 277 EILALQMQRGRA 288
++ L+ Q A
Sbjct: 2601 QLQLLEEQHRAA 2612
Score = 29.6 bits (65), Expect = 8.1
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGA- 171
R++ AE+EA +R QL EE RR R R+ Q+ + EA R R A
Sbjct: 1964 RSKEQAELEA-ARQRQLAAEEERRR-------REAEERV----QKSLAAEEEAARQRKAA 2011
Query: 172 ---LEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
+E L A+++E + L R E E +Q A ++A +A+ +
Sbjct: 2012 LEEVERLKAKVEEARR-----LRERAEQESARQLQLAQEAA-QKRLQAEEKAHAFAVQQK 2065
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
L Q LQ E S L+ R + R A EAE R++AE A Q +R
Sbjct: 2066 EQELQQT--LQQEQSVLDQLRGEAEAARRAAE-------EAEEARVQAEREAAQSRR 2113
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/197 (23%), Positives = 82/197 (41%), Gaps = 14/197 (7%)
Query: 86 RSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-RALQLRGEELSRRLQVVACT 144
R +A + + +E+ + ARR + E Q+ R +L +EL ++ Q+
Sbjct: 1645 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLA--- 1701
Query: 145 RGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL-YSPVQ 203
G + EQE+ L+AE + ++L + LQ E R+E E + V+
Sbjct: 1702 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1761
Query: 204 KANPGTLAAEIRALREAYI---RDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260
LA++ RA E+ + R G+ +L EA+ L + +R R
Sbjct: 1762 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---- 1817
Query: 261 SGELPVVEAENRRLEAE 277
+L +A +R EAE
Sbjct: 1818 --QLAEEDAARQRAEAE 1832
Score = 32.0 bits (71), Expect = 1.6
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 42/210 (20%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRR-LQVVACTRGG 147
AR +S + E + S ++ L + +AR +EA++RAL LR ++ ++R LQ A
Sbjct: 2220 ARQRSQVEEELFSVRVQMEELSKLKAR----IEAENRALILRDKDNTQRFLQEEA----- 2270
Query: 148 MSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANP 207
++++++ EA R A + AR+++L E + E L +Q
Sbjct: 2271 --------EKMKQVAEEAARLSVAAQE-AARLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2321
Query: 208 GT-LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPV 266
T L AE L++ Q Q +A L+ + Q + A T G
Sbjct: 2322 ATRLKAEAELLQQ--------------QKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2367
Query: 267 VEAENRR-----LEAEILAL---QMQRGRA 288
+EAE +R EAE L L +M R +A
Sbjct: 2368 LEAERQRQLEMSAEAERLKLRVAEMSRAQA 2397
Score = 30.8 bits (68), Expect = 3.6
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Query: 103 SERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQ------VVACTRGGMSRLFGLEQ 156
+ERLR R +++ +++ LQL+ EE+ Q A + +S L Q
Sbjct: 2445 AERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ 2504
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRA 216
R ++ E + + A+ Q+L+ E R++ ++ Q+ + +
Sbjct: 2505 RERFIEQEKAKLEQLFQDEVAKAQQLREE-----QQRQQQQMEQERQRL--------VAS 2551
Query: 217 LREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEA 276
+ EA R + GV + Q E LE QR Q ++ EN+RL
Sbjct: 2552 MEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEE-----------LLAEENQRLRE 2596
Query: 277 EILALQMQRGRA 288
++ L+ Q A
Sbjct: 2597 QLQLLEEQHRAA 2608
Score = 29.6 bits (65), Expect = 8.1
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGA- 171
R++ AE+EA +R QL EE RR R R+ Q+ + EA R R A
Sbjct: 1960 RSKEQAELEA-ARQRQLAAEEERRR-------REAEERV----QKSLAAEEEAARQRKAA 2007
Query: 172 ---LEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
+E L A+++E + L R E E +Q A ++A +A+ +
Sbjct: 2008 LEEVERLKAKVEEARR-----LRERAEQESARQLQLAQEAA-QKRLQAEEKAHAFAVQQK 2061
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
L Q LQ E S L+ R + R A EAE R++AE A Q +R
Sbjct: 2062 EQELQQT--LQQEQSVLDQLRGEAEAARRAAE-------EAEEARVQAEREAAQSRR 2109
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/197 (23%), Positives = 82/197 (41%), Gaps = 14/197 (7%)
Query: 86 RSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-RALQLRGEELSRRLQVVACT 144
R +A + + +E+ + ARR + E Q+ R +L +EL ++ Q+
Sbjct: 1613 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLA--- 1669
Query: 145 RGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL-YSPVQ 203
G + EQE+ L+AE + ++L + LQ E R+E E + V+
Sbjct: 1670 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1729
Query: 204 KANPGTLAAEIRALREAYI---RDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260
LA++ RA E+ + R G+ +L EA+ L + +R R
Sbjct: 1730 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---- 1785
Query: 261 SGELPVVEAENRRLEAE 277
+L +A +R EAE
Sbjct: 1786 --QLAEEDAARQRAEAE 1800
Score = 32.0 bits (71), Expect = 1.6
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 42/210 (20%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRR-LQVVACTRGG 147
AR +S + E + S ++ L + +AR +EA++RAL LR ++ ++R LQ A
Sbjct: 2188 ARQRSQVEEELFSVRVQMEELSKLKAR----IEAENRALILRDKDNTQRFLQEEA----- 2238
Query: 148 MSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANP 207
++++++ EA R A + AR+++L E + E L +Q
Sbjct: 2239 --------EKMKQVAEEAARLSVAAQE-AARLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2289
Query: 208 GT-LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPV 266
T L AE L++ Q Q +A L+ + Q + A T G
Sbjct: 2290 ATRLKAEAELLQQ--------------QKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2335
Query: 267 VEAENRR-----LEAEILAL---QMQRGRA 288
+EAE +R EAE L L +M R +A
Sbjct: 2336 LEAERQRQLEMSAEAERLKLRVAEMSRAQA 2365
Score = 30.8 bits (68), Expect = 3.6
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Query: 103 SERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQ------VVACTRGGMSRLFGLEQ 156
+ERLR R +++ +++ LQL+ EE+ Q A + +S L Q
Sbjct: 2413 AERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ 2472
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRA 216
R ++ E + + A+ Q+L+ E R++ ++ Q+ + +
Sbjct: 2473 RERFIEQEKAKLEQLFQDEVAKAQQLREE-----QQRQQQQMEQERQRL--------VAS 2519
Query: 217 LREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEA 276
+ EA R + GV + Q E LE QR Q ++ EN+RL
Sbjct: 2520 MEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEE-----------LLAEENQRLRE 2564
Query: 277 EILALQMQRGRA 288
++ L+ Q A
Sbjct: 2565 QLQLLEEQHRAA 2576
Score = 29.6 bits (65), Expect = 8.1
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGA- 171
R++ AE+EA +R QL EE RR R R+ Q+ + EA R R A
Sbjct: 1928 RSKEQAELEA-ARQRQLAAEEERRR-------REAEERV----QKSLAAEEEAARQRKAA 1975
Query: 172 ---LEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
+E L A+++E + L R E E +Q A ++A +A+ +
Sbjct: 1976 LEEVERLKAKVEEARR-----LRERAEQESARQLQLAQEAA-QKRLQAEEKAHAFAVQQK 2029
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
L Q LQ E S L+ R + R A EAE R++AE A Q +R
Sbjct: 2030 EQELQQT--LQQEQSVLDQLRGEAEAARRAAE-------EAEEARVQAEREAAQSRR 2077
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/197 (23%), Positives = 82/197 (41%), Gaps = 14/197 (7%)
Query: 86 RSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-RALQLRGEELSRRLQVVACT 144
R +A + + +E+ + ARR + E Q+ R +L +EL ++ Q+
Sbjct: 1782 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLA--- 1838
Query: 145 RGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL-YSPVQ 203
G + EQE+ L+AE + ++L + LQ E R+E E + V+
Sbjct: 1839 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1898
Query: 204 KANPGTLAAEIRALREAYI---RDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260
LA++ RA E+ + R G+ +L EA+ L + +R R
Sbjct: 1899 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---- 1954
Query: 261 SGELPVVEAENRRLEAE 277
+L +A +R EAE
Sbjct: 1955 --QLAEEDAARQRAEAE 1969
Score = 32.0 bits (71), Expect = 1.6
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 42/210 (20%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRR-LQVVACTRGG 147
AR +S + E + S ++ L + +AR +EA++RAL LR ++ ++R LQ A
Sbjct: 2357 ARQRSQVEEELFSVRVQMEELSKLKAR----IEAENRALILRDKDNTQRFLQEEA----- 2407
Query: 148 MSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANP 207
++++++ EA R A + AR+++L E + E L +Q
Sbjct: 2408 --------EKMKQVAEEAARLSVAAQE-AARLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2458
Query: 208 GT-LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPV 266
T L AE L++ Q Q +A L+ + Q + A T G
Sbjct: 2459 ATRLKAEAELLQQ--------------QKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2504
Query: 267 VEAENRR-----LEAEILAL---QMQRGRA 288
+EAE +R EAE L L +M R +A
Sbjct: 2505 LEAERQRQLEMSAEAERLKLRVAEMSRAQA 2534
Score = 30.8 bits (68), Expect = 3.6
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Query: 103 SERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQ------VVACTRGGMSRLFGLEQ 156
+ERLR R +++ +++ LQL+ EE+ Q A + +S L Q
Sbjct: 2582 AERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ 2641
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRA 216
R ++ E + + A+ Q+L+ E R++ ++ Q+ + +
Sbjct: 2642 RERFIEQEKAKLEQLFQDEVAKAQQLREE-----QQRQQQQMEQERQRL--------VAS 2688
Query: 217 LREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEA 276
+ EA R + GV + Q E LE QR Q ++ EN+RL
Sbjct: 2689 MEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEE-----------LLAEENQRLRE 2733
Query: 277 EILALQMQRGRA 288
++ L+ Q A
Sbjct: 2734 QLQLLEEQHRAA 2745
Score = 29.6 bits (65), Expect = 8.1
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGA- 171
R++ AE+EA +R QL EE RR R R+ Q+ + EA R R A
Sbjct: 2097 RSKEQAELEA-ARQRQLAAEEERRR-------REAEERV----QKSLAAEEEAARQRKAA 2144
Query: 172 ---LEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
+E L A+++E + L R E E +Q A ++A +A+ +
Sbjct: 2145 LEEVERLKAKVEEARR-----LRERAEQESARQLQLAQEAA-QKRLQAEEKAHAFAVQQK 2198
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
L Q LQ E S L+ R + R A EAE R++AE A Q +R
Sbjct: 2199 EQELQQT--LQQEQSVLDQLRGEAEAARRAAE-------EAEEARVQAEREAAQSRR 2246
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/197 (23%), Positives = 82/197 (41%), Gaps = 14/197 (7%)
Query: 86 RSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-RALQLRGEELSRRLQVVACT 144
R +A + + +E+ + ARR + E Q+ R +L +EL ++ Q+
Sbjct: 1623 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLA--- 1679
Query: 145 RGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL-YSPVQ 203
G + EQE+ L+AE + ++L + LQ E R+E E + V+
Sbjct: 1680 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1739
Query: 204 KANPGTLAAEIRALREAYI---RDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260
LA++ RA E+ + R G+ +L EA+ L + +R R
Sbjct: 1740 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---- 1795
Query: 261 SGELPVVEAENRRLEAE 277
+L +A +R EAE
Sbjct: 1796 --QLAEEDAARQRAEAE 1810
Score = 32.0 bits (71), Expect = 1.6
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 42/210 (20%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRR-LQVVACTRGG 147
AR +S + E + S ++ L + +AR +EA++RAL LR ++ ++R LQ A
Sbjct: 2198 ARQRSQVEEELFSVRVQMEELSKLKAR----IEAENRALILRDKDNTQRFLQEEA----- 2248
Query: 148 MSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANP 207
++++++ EA R A + AR+++L E + E L +Q
Sbjct: 2249 --------EKMKQVAEEAARLSVAAQE-AARLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2299
Query: 208 GT-LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPV 266
T L AE L++ Q Q +A L+ + Q + A T G
Sbjct: 2300 ATRLKAEAELLQQ--------------QKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2345
Query: 267 VEAENRR-----LEAEILAL---QMQRGRA 288
+EAE +R EAE L L +M R +A
Sbjct: 2346 LEAERQRQLEMSAEAERLKLRVAEMSRAQA 2375
Score = 30.8 bits (68), Expect = 3.6
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Query: 103 SERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQ------VVACTRGGMSRLFGLEQ 156
+ERLR R +++ +++ LQL+ EE+ Q A + +S L Q
Sbjct: 2423 AERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ 2482
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRA 216
R ++ E + + A+ Q+L+ E R++ ++ Q+ + +
Sbjct: 2483 RERFIEQEKAKLEQLFQDEVAKAQQLREE-----QQRQQQQMEQERQRL--------VAS 2529
Query: 217 LREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEA 276
+ EA R + GV + Q E LE QR Q ++ EN+RL
Sbjct: 2530 MEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEE-----------LLAEENQRLRE 2574
Query: 277 EILALQMQRGRA 288
++ L+ Q A
Sbjct: 2575 QLQLLEEQHRAA 2586
Score = 29.6 bits (65), Expect = 8.1
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGA- 171
R++ AE+EA +R QL EE RR R R+ Q+ + EA R R A
Sbjct: 1938 RSKEQAELEA-ARQRQLAAEEERRR-------REAEERV----QKSLAAEEEAARQRKAA 1985
Query: 172 ---LEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
+E L A+++E + L R E E +Q A ++A +A+ +
Sbjct: 1986 LEEVERLKAKVEEARR-----LRERAEQESARQLQLAQEAA-QKRLQAEEKAHAFAVQQK 2039
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
L Q LQ E S L+ R + R A EAE R++AE A Q +R
Sbjct: 2040 EQELQQT--LQQEQSVLDQLRGEAEAARRAAE-------EAEEARVQAEREAAQSRR 2087
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/197 (23%), Positives = 82/197 (41%), Gaps = 14/197 (7%)
Query: 86 RSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-RALQLRGEELSRRLQVVACT 144
R +A + + +E+ + ARR + E Q+ R +L +EL ++ Q+
Sbjct: 1631 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLA--- 1687
Query: 145 RGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL-YSPVQ 203
G + EQE+ L+AE + ++L + LQ E R+E E + V+
Sbjct: 1688 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1747
Query: 204 KANPGTLAAEIRALREAYI---RDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260
LA++ RA E+ + R G+ +L EA+ L + +R R
Sbjct: 1748 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---- 1803
Query: 261 SGELPVVEAENRRLEAE 277
+L +A +R EAE
Sbjct: 1804 --QLAEEDAARQRAEAE 1818
Score = 32.0 bits (71), Expect = 1.6
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 42/210 (20%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRR-LQVVACTRGG 147
AR +S + E + S ++ L + +AR +EA++RAL LR ++ ++R LQ A
Sbjct: 2206 ARQRSQVEEELFSVRVQMEELSKLKAR----IEAENRALILRDKDNTQRFLQEEA----- 2256
Query: 148 MSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANP 207
++++++ EA R A + AR+++L E + E L +Q
Sbjct: 2257 --------EKMKQVAEEAARLSVAAQE-AARLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2307
Query: 208 GT-LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPV 266
T L AE L++ Q Q +A L+ + Q + A T G
Sbjct: 2308 ATRLKAEAELLQQ--------------QKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2353
Query: 267 VEAENRR-----LEAEILAL---QMQRGRA 288
+EAE +R EAE L L +M R +A
Sbjct: 2354 LEAERQRQLEMSAEAERLKLRVAEMSRAQA 2383
Score = 30.8 bits (68), Expect = 3.6
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Query: 103 SERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQ------VVACTRGGMSRLFGLEQ 156
+ERLR R +++ +++ LQL+ EE+ Q A + +S L Q
Sbjct: 2431 AERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ 2490
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRA 216
R ++ E + + A+ Q+L+ E R++ ++ Q+ + +
Sbjct: 2491 RERFIEQEKAKLEQLFQDEVAKAQQLREE-----QQRQQQQMEQERQRL--------VAS 2537
Query: 217 LREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEA 276
+ EA R + GV + Q E LE QR Q ++ EN+RL
Sbjct: 2538 MEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEE-----------LLAEENQRLRE 2582
Query: 277 EILALQMQRGRA 288
++ L+ Q A
Sbjct: 2583 QLQLLEEQHRAA 2594
Score = 29.6 bits (65), Expect = 8.1
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGA- 171
R++ AE+EA +R QL EE RR R R+ Q+ + EA R R A
Sbjct: 1946 RSKEQAELEA-ARQRQLAAEEERRR-------REAEERV----QKSLAAEEEAARQRKAA 1993
Query: 172 ---LEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
+E L A+++E + L R E E +Q A ++A +A+ +
Sbjct: 1994 LEEVERLKAKVEEARR-----LRERAEQESARQLQLAQEAA-QKRLQAEEKAHAFAVQQK 2047
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
L Q LQ E S L+ R + R A EAE R++AE A Q +R
Sbjct: 2048 EQELQQT--LQQEQSVLDQLRGEAEAARRAAE-------EAEEARVQAEREAAQSRR 2095
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/197 (23%), Positives = 82/197 (41%), Gaps = 14/197 (7%)
Query: 86 RSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQS-RALQLRGEELSRRLQVVACT 144
R +A + + +E+ + ARR + E Q+ R +L +EL ++ Q+
Sbjct: 1672 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLA--- 1728
Query: 145 RGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAEL-YSPVQ 203
G + EQE+ L+AE + ++L + LQ E R+E E + V+
Sbjct: 1729 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1788
Query: 204 KANPGTLAAEIRALREAYI---RDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260
LA++ RA E+ + R G+ +L EA+ L + +R R
Sbjct: 1789 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---- 1844
Query: 261 SGELPVVEAENRRLEAE 277
+L +A +R EAE
Sbjct: 1845 --QLAEEDAARQRAEAE 1859
Score = 32.0 bits (71), Expect = 1.6
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 42/210 (20%)
Query: 89 ARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRR-LQVVACTRGG 147
AR +S + E + S ++ L + +AR +EA++RAL LR ++ ++R LQ A
Sbjct: 2247 ARQRSQVEEELFSVRVQMEELSKLKAR----IEAENRALILRDKDNTQRFLQEEA----- 2297
Query: 148 MSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANP 207
++++++ EA R A + AR+++L E + E L +Q
Sbjct: 2298 --------EKMKQVAEEAARLSVAAQE-AARLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2348
Query: 208 GT-LAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPV 266
T L AE L++ Q Q +A L+ + Q + A T G
Sbjct: 2349 ATRLKAEAELLQQ--------------QKELAQEQARRLQEDKEQMAQQLAEETQGFQRT 2394
Query: 267 VEAENRR-----LEAEILAL---QMQRGRA 288
+EAE +R EAE L L +M R +A
Sbjct: 2395 LEAERQRQLEMSAEAERLKLRVAEMSRAQA 2424
Score = 30.8 bits (68), Expect = 3.6
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Query: 103 SERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQ------VVACTRGGMSRLFGLEQ 156
+ERLR R +++ +++ LQL+ EE+ Q A + +S L Q
Sbjct: 2472 AERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ 2531
Query: 157 EIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRA 216
R ++ E + + A+ Q+L+ E R++ ++ Q+ + +
Sbjct: 2532 RERFIEQEKAKLEQLFQDEVAKAQQLREE-----QQRQQQQMEQERQRL--------VAS 2578
Query: 217 LREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEA 276
+ EA R + GV + Q E LE QR Q ++ EN+RL
Sbjct: 2579 MEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEE-----------LLAEENQRLRE 2623
Query: 277 EILALQMQRGRA 288
++ L+ Q A
Sbjct: 2624 QLQLLEEQHRAA 2635
Score = 29.6 bits (65), Expect = 8.1
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%)
Query: 113 RARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGA- 171
R++ AE+EA +R QL EE RR R R+ Q+ + EA R R A
Sbjct: 1987 RSKEQAELEA-ARQRQLAAEEERRR-------REAEERV----QKSLAAEEEAARQRKAA 2034
Query: 172 ---LEVLGARIQELQAEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRD 228
+E L A+++E + L R E E +Q A ++A +A+ +
Sbjct: 2035 LEEVERLKAKVEEARR-----LRERAEQESARQLQLAQEAA-QKRLQAEEKAHAFAVQQK 2088
Query: 229 PGVLGQIWQLQVEASALELQRSQTRRGRAGATSGELPVVEAENRRLEAEILALQMQR 285
L Q LQ E S L+ R + R A EAE R++AE A Q +R
Sbjct: 2089 EQELQQT--LQQEQSVLDQLRGEAEAARRAAE-------EAEEARVQAEREAAQSRR 2136
>gi|123173757 RAVER1 [Homo sapiens]
Length = 756
Score = 38.1 bits (87), Expect = 0.023
Identities = 95/349 (27%), Positives = 122/349 (34%), Gaps = 70/349 (20%)
Query: 141 VACTRGGMSRLFG-LEQEIRELQAEAGRTRGALEVLGARIQELQAEPGNPLSSRREAELY 199
+AC + G + F LE E E+ EA + L + G+ ++ PG P S
Sbjct: 270 LACGQDGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSM------ 323
Query: 200 SPVQKANPGTLAAEIRALREAYIRDGGR--DPGVLGQIWQLQVEASALELQRSQTRRGRA 257
LAA I A A R G +P +L + L AS L+L + G A
Sbjct: 324 ----------LAALIAAQATALNRGKGLLPEPNILQLLNNLGPSAS-LQLLLNPLLHGSA 372
Query: 258 GATSGEL------PVVEAENRRLEAEILALQMQRGRAP--LGPQDLRLLGDASLQ----- 304
G G L P++ LALQ Q + P LG L L +
Sbjct: 373 GGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLL 432
Query: 305 ---PKGRRDPPLLPPPVAPPLPPLPGFSEPQ------------------------LPGTM 337
P G PP LPP P P LP P L G+
Sbjct: 433 GELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGSG 492
Query: 338 TRNLGLDSHFL--LPTSDMLGPAPYDPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRD 395
R L DS L P +LG P D L + + L AS + + G GR
Sbjct: 493 LRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGR- 551
Query: 396 TGRTTALPPALCLPPPPAPGPMGNCAI-LASRQPVP----RLPPSSSVS 439
+ R PP PP P G + A L SR P RLPP +S
Sbjct: 552 SRRPAEGPPT--NPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLS 598
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,444,791
Number of Sequences: 37866
Number of extensions: 1562033
Number of successful extensions: 14994
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 320
Number of HSP's that attempted gapping in prelim test: 12050
Number of HSP's gapped (non-prelim): 2515
length of query: 590
length of database: 18,247,518
effective HSP length: 108
effective length of query: 482
effective length of database: 14,157,990
effective search space: 6824151180
effective search space used: 6824151180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.