Guide to the Human Genome
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Search of human proteins with 169234617

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169234617 RAD9 homolog B [Homo sapiens]
         (429 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169234617 RAD9 homolog B [Homo sapiens]                            860   0.0  
gi|4759022 RAD9 homolog [Homo sapiens]                                224   9e-59
gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo sapi...    33   0.65 
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         30   3.2  
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           30   5.5  
gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo sa...    30   5.5  
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       29   7.2  
gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]       29   7.2  
gi|226371708 exocyst complex component 3-like 2 [Homo sapiens]         29   9.4  

>gi|169234617 RAD9 homolog B [Homo sapiens]
          Length = 429

 Score =  860 bits (2222), Expect = 0.0
 Identities = 429/429 (100%), Positives = 429/429 (100%)

Query: 1   MAAMLKCVMSGSQVKVFGKAVQALSRISDEFWLDPSKKGLALRCVNSSRSAYGCVLFSPV 60
           MAAMLKCVMSGSQVKVFGKAVQALSRISDEFWLDPSKKGLALRCVNSSRSAYGCVLFSPV
Sbjct: 1   MAAMLKCVMSGSQVKVFGKAVQALSRISDEFWLDPSKKGLALRCVNSSRSAYGCVLFSPV 60

Query: 61  FFQHYQWSALVKMSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIFTRSDKCK 120
           FFQHYQWSALVKMSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIFTRSDKCK
Sbjct: 61  FFQHYQWSALVKMSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIFTRSDKCK 120

Query: 121 VVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFTSSQEEVT 180
           VVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFTSSQEEVT
Sbjct: 121 VVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFTSSQEEVT 180

Query: 181 LAVTPLNFCLKSSNEESMDLSNAVHSEMFVGSDEFDFFQIGMDTEITFCFKELKGILTFS 240
           LAVTPLNFCLKSSNEESMDLSNAVHSEMFVGSDEFDFFQIGMDTEITFCFKELKGILTFS
Sbjct: 181 LAVTPLNFCLKSSNEESMDLSNAVHSEMFVGSDEFDFFQIGMDTEITFCFKELKGILTFS 240

Query: 241 EATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCLSQKRKRSDL 300
           EATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCLSQKRKRSDL
Sbjct: 241 EATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCLSQKRKRSDL 300

Query: 301 IEKKAGKNVTGQALECISKKAAPRRLYPKETLTNISALENCGSPAMKRVDGDVSEVSESS 360
           IEKKAGKNVTGQALECISKKAAPRRLYPKETLTNISALENCGSPAMKRVDGDVSEVSESS
Sbjct: 301 IEKKAGKNVTGQALECISKKAAPRRLYPKETLTNISALENCGSPAMKRVDGDVSEVSESS 360

Query: 361 VSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMNNVCCRKEFNG 420
           VSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMNNVCCRKEFNG
Sbjct: 361 VSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMNNVCCRKEFNG 420

Query: 421 SDAKYFCII 429
           SDAKYFCII
Sbjct: 421 SDAKYFCII 429


>gi|4759022 RAD9 homolog [Homo sapiens]
          Length = 391

 Score =  224 bits (572), Expect = 9e-59
 Identities = 136/383 (35%), Positives = 216/383 (56%), Gaps = 17/383 (4%)

Query: 5   LKCVMSGSQVKVFGKAVQALSRISDEFWLDPSKKGLALRCVNSSRSAYGCVLFSPVFFQH 64
           +KC+++G  VKV GKAV +LSRI DE +L+P + GL+LR VNSSRSAY C LF+P+FFQ 
Sbjct: 1   MKCLVTGGNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQ 60

Query: 65  YQWSALVKMSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIFTRSDKCKVVIQ 124
           YQ          +L     L+CK+ MKS L +FR L  LE+ +EKC I       ++V+Q
Sbjct: 61  YQ----AATPGQDL-----LRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQ 111

Query: 125 FFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFTSSQEEVTLAV- 183
              + G+++THN+ FQ+ + LQ +FD   C + L    R+L +A++ F+ +  EVTL + 
Sbjct: 112 LHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIG 171

Query: 184 TPLNFCLKSSNEESMD-LSNAVHSEMFVGSDEFDFFQIGMDTEITFCFKELKGILTFSEA 242
                 L+S +EE  D  + A+ +EM +G ++F   Q      ITFC KE +G+L+F+E+
Sbjct: 172 RGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAES 231

Query: 243 THAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCLSQKRKRSDLIE 302
            +  +SI+FD PG+P   +I D L++ +F+LATL+D  S +   Q L   ++ +    ++
Sbjct: 232 ANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHS---QDLGSPERHQPVPQLQ 288

Query: 303 KKAGKNVTGQALECI-SKKAAPRRLYPKETLTNISALENCGSPAMKRVDGDVSEVSESSV 361
             +  +    A + I S   A       E    + ++     P   +  G  SE  + + 
Sbjct: 289 AHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDEAE 348

Query: 362 SNTEEVPGSLCLRKFSCMFFGAV 384
            +T  VPG+   +KF  +FFG++
Sbjct: 349 PST--VPGTPPPKKFRSLFFGSI 369


>gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo
          sapiens]
          Length = 1522

 Score = 32.7 bits (73), Expect = 0.65
 Identities = 19/60 (31%), Positives = 29/60 (48%)

Query: 5  LKCVMSGSQVKVFGKAVQALSRISDEFWLDPSKKGLALRCVNSSRSAYGCVLFSPVFFQH 64
          +K + S    K F KA++++     E +L    +  AL+   + RS Y C  FS V F H
Sbjct: 11 VKFLKSSDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKENDRSLYICDPFSGVVFDH 70


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 296  KRSDLIEKKAGKNVTGQALECISKKAAPRRLYPKETLTNISALENCGSPAMKRVDGDVSE 355
            K S  ++    K+  G+ L+ +S+  +P+   P E+ ++ S+L +C     K +D D+S 
Sbjct: 2809 KESLALQGTHEKDTEGEELD-VSRAESPQADCPSESFSSSSSLPHCLVSEGKELDEDIS- 2866

Query: 356  VSESSVSNTE 365
             + SS+  TE
Sbjct: 2867 -ATSSIQKTE 2875


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 29.6 bits (65), Expect = 5.5
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 5/42 (11%)

Query: 25   SRISDEFWLDPSKKGLALRCVNSSRSAYGCVLFSPVFFQHYQ 66
            +RI D F ++PSK      C+ S   A+  V F+P   Q+YQ
Sbjct: 3407 ARIVDIFEVEPSKM-----CIASHSHAFATVSFTPQIMQNYQ 3443


>gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo
           sapiens]
          Length = 601

 Score = 29.6 bits (65), Expect = 5.5
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)

Query: 338 LENCGSPAMKRVDGDVSEVSESSVSNTEEVPGSL-CLRKFSCMFFGAVSSDQQEHF-NHP 395
           +E   +PAM +   ++    + ++SN E +PG    LR+        + S  +E F N+P
Sbjct: 249 MELARNPAMMQ---EMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNP 305

Query: 396 FDSLARASDS 405
           F SLA  SDS
Sbjct: 306 FSSLAGNSDS 315


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 279 EQSRASSPQSLCLSQK--RKRSDLIEKKAGKNVTGQALECISKKAAPRRLYPKE-TLTNI 335
           E++ A SP  L  S K  R+  +     A    T      + K+ APR L PK+ +  N+
Sbjct: 517 EKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANV 576

Query: 336 SALENCGSPAMKR 348
           +A     +PA+K+
Sbjct: 577 AA----ATPAIKK 585


>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
          Length = 1189

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 279 EQSRASSPQSLCLSQK--RKRSDLIEKKAGKNVTGQALECISKKAAPRRLYPKE-TLTNI 335
           E++ A SP  L  S K  R+  +     A    T      + K+ APR L PK+ +  N+
Sbjct: 517 EKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANV 576

Query: 336 SALENCGSPAMKR 348
           +A     +PA+K+
Sbjct: 577 AA----ATPAIKK 585


>gi|226371708 exocyst complex component 3-like 2 [Homo sapiens]
          Length = 409

 Score = 28.9 bits (63), Expect = 9.4
 Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 10/88 (11%)

Query: 312 QALECISKKAAPRRLYPKETLTNISALENCGSP------AMKRVDGDVSEVSESSVSNTE 365
           Q +E   +  A R + P   ++   AL NCG P       + RV    SE +  + ++  
Sbjct: 101 QRVERFHENPAVREMLPDTYISKTIALVNCGPPLRALAERLARVGPPESEPAREASASAL 160

Query: 366 EVPGSLCLRKFSCMFFGAVSSDQQEHFN 393
           +    LC R  + + F     + Q HFN
Sbjct: 161 DHVTRLCHRVVANLLF----QELQPHFN 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.133    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,147,529
Number of Sequences: 37866
Number of extensions: 622065
Number of successful extensions: 1433
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1425
Number of HSP's gapped (non-prelim): 11
length of query: 429
length of database: 18,247,518
effective HSP length: 105
effective length of query: 324
effective length of database: 14,271,588
effective search space: 4623994512
effective search space used: 4623994512
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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