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Search of human proteins with 169218106
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
(436 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 855 0.0
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 437 e-123
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 411 e-115
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 394 e-110
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 390 e-108
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 384 e-107
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 344 1e-94
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 319 3e-87
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 319 3e-87
gi|148746195 trichohyalin [Homo sapiens] 214 2e-55
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 202 6e-52
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 189 4e-48
gi|44890059 involucrin [Homo sapiens] 177 2e-44
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 176 3e-44
gi|221219020 NYD-SP11 protein [Homo sapiens] 154 1e-37
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 152 8e-37
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 150 2e-36
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 150 3e-36
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 148 8e-36
gi|221139761 zinc finger protein 853 [Homo sapiens] 146 3e-35
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 137 1e-32
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 136 4e-32
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 135 1e-31
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 131 1e-30
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 131 1e-30
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 131 1e-30
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 131 1e-30
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 129 7e-30
gi|21735548 centrosomal protein 2 [Homo sapiens] 128 9e-30
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 122 6e-28
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 855 bits (2208), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ
Sbjct: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ
Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
Query: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
Query: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ 420
MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ
Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ 420
Query: 421 KEQMRKQEEHMGEQKE 436
KEQMRKQEEHMGEQKE
Sbjct: 421 KEQMRKQEEHMGEQKE 436
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 437 bits (1124), Expect = e-123
Identities = 253/524 (48%), Positives = 369/524 (70%), Gaps = 92/524 (17%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLP-------------Q 50
ITNEELK+KNAELQE+L+L E+EKSEIQL++KELKRKLE K LP Q
Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239
Query: 51 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 110
E ++REQE ++R+QE ++ QE ++REQEG++REQE ++R QE ++REQE ++REQE ++
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 111 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 170
REQ+ ++REQE Q++EQE ++ EQE ++REQE ++ QE ++ EQE Q+REQE ++R+QE
Sbjct: 300 REQK-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Query: 171 GQVREQEGQVREQEGQVREQ------------EGQMGEQEGQMGEQEEQMGEQEEQMQKQ 218
++ EQ+ ++RE+E ++REQ E ++ E+E +M E+EE M EQEE+MQKQ
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 219 EEQMGEQE---------------------------------------------------- 226
EE M EQE
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Query: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE------QEEQMLK 280
E+MR+QE+QM EQEE+++ QE+++ QEE+M +Q+E++RE+EE+MRE QEE+M +
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Query: 281 QKEQTEQEEQTGEQEEQMREQ------EEQMREQEEQMREQEEQMREQEEQMGKQEEQMW 334
+K+ EQE++T +QEE+MRE+ E++MRE+EE MREQEE+M+EQEE+M +QEE+MW
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW 598
Query: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQ--MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
EQ+E+M EQ+E+MW+QEE+M EQEE+ MQ+QEE + +QEE+M++QEE+M +QEE+MR+Q
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658
Query: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
EE+M EQ+E+M Q+E+MREQEE+M Q+E+MR+QEE M Q+E
Sbjct: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
Score = 298 bits (762), Expect = 8e-81
Identities = 192/468 (41%), Positives = 307/468 (65%), Gaps = 87/468 (18%)
Query: 3 RITNEELKEKNAELQEELQLVETEKS----EIQLHIKELKRKLETDKIPLPQEGQVREQE 58
R +EL+E+ EL+E+ +L E E+ E ++ +E K + + +K+ QE ++ EQE
Sbjct: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM-WRQEERLWEQE 344
Query: 59 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG------------QVREQEGQVREQ 106
Q+REQE ++R+QE ++ EQ+ ++RE+E ++REQE ++RE+E ++RE+
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Query: 107 EGQVREQEGQVREQEGQVREQEGQ-------------------VREQEGQVREQEGQVRE 147
E +REQE ++++QE + EQE + ++EQE ++ EQE ++R+
Sbjct: 405 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 464
Query: 148 QE---GQ---------VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMG 195
QE GQ +REQE Q+ EQE ++R+QE ++ +QE ++ EQ+ ++RE+E +M
Sbjct: 465 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR 524
Query: 196 EQ--------------------------------EGQMGEQEEQMGEQEEQMQKQEEQMG 223
EQ E +M E+E++M E+EE M++QEE+M
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584
Query: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ--MREQEEQMREQEEQMLKQ 281
EQEE+MR+QEE+M EQEE++Q+QEE++ +QEE+M +QEE+ M+EQEE M EQEE+M +Q
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 282 KEQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
+E+ EQEE+ EQEE+MREQEE+M+ QEE+MREQEE+M+ QEE+M +QEE+M Q+E+M
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Query: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
W Q+E+MW QEE+M QEE M+++EE++R Q+E+M +E++ + EE+
Sbjct: 705 WGQEEKMWGQEEKMWGQEE-MREKEERIRDQKEKM---QERLPEHEER 748
Score = 238 bits (608), Expect = 6e-63
Identities = 140/325 (43%), Positives = 236/325 (72%), Gaps = 11/325 (3%)
Query: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
+P + +++ + QEE + EK Q + ++K+ + QE Q+ EQE +
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+R+QE ++ +QE ++ EQ+ ++RE+E ++REQ+ ++ +QE ++RE E + +EQE + +Q
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQK-KMWQQEEKMRE-EKKTQEQEKKTWDQ 552
Query: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
E ++RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++
Sbjct: 553 EEKMREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611
Query: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
EQE ++ EQ E+E +M EQEE M EQEE+MQ+QEE+M EQEE+MR+QEE+M EQE
Sbjct: 612 WEQEEKMWEQ-----EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
E++Q QEE++++QEE+M+ QEE+MREQEE+MR QEE+M Q+E+ +E+ +E+MRE
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE 726
Query: 301 QEEQMREQEEQMREQEEQMREQEEQ 325
+EE++R+Q+E+M +E++ E EE+
Sbjct: 727 KEERIRDQKEKM---QERLPEHEER 748
Score = 169 bits (428), Expect = 5e-42
Identities = 107/325 (32%), Positives = 202/325 (62%), Gaps = 19/325 (5%)
Query: 126 EQEGQVREQEGQVREQEGQ---VREQEGQVREQEGQVREQEGQVREQE----GQVREQEG 178
E++ + QE RE E Q +R Q E E + + R+ E G+ ++ G
Sbjct: 72 EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG 131
Query: 179 QVREQ---EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
++ G+++ + + E++ ++ + + + + E+++K+ +
Sbjct: 132 RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAE 191
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE---QEEQMLKQKEQTEQEEQTG 292
+ E+ + ++ ++Q ++++++ E+ + Q++ QEE +++E EQE++
Sbjct: 192 LQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 251
Query: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQ 350
+QEE+M QEE++REQE +MREQEE+MR QE+++ +QE+++ EQ++ E +EQ + +Q
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK---ELREQKKLREQ 308
Query: 351 EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQM 410
EEQM EQEE+M +QEE++R+QEE+M +QEE++ +QE+QMR+QE++M +Q+E+M EQ E++
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 411 REQEEQMGEQKEQMRKQEEHMGEQK 435
RE+EE+M EQ E+M +QEE M E++
Sbjct: 369 REKEERMREQ-EKMWEQEEKMQEEE 392
Score = 120 bits (302), Expect = 2e-27
Identities = 65/179 (36%), Positives = 122/179 (68%), Gaps = 12/179 (6%)
Query: 268 EEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
EE +E++ L+ T E +++ E +E++R E + E + ++E + ++ +
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
Query: 324 EQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMR 383
+ + + + E+MW Q+E++ +QE+++ +QEE+M +QEE++R+QE +MR+QEE+MR
Sbjct: 222 FLLPQVQTNTLQ--EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279
Query: 384 KQEEQMRKQEEQMGEQKEQMGEQK------EQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+QE+++R+QE+++ EQ++++ EQK EQM+EQEE+M EQ+E+MR+QEE M Q+E
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 411 bits (1056), Expect = e-115
Identities = 245/546 (44%), Positives = 363/546 (66%), Gaps = 114/546 (20%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ------------- 50
ITNEELK+KNAELQE+L L E+EKSEIQL++KELKRKLE K LPQ
Sbjct: 218 ITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 277
Query: 51 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 110
E ++REQE ++R+QE ++ QE ++REQEG++REQE ++ QE ++REQE ++REQE ++
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 111 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 170
REQ+ ++REQE Q++EQE ++ EQE ++REQE ++ QE ++ EQE Q+REQE ++R+QE
Sbjct: 338 REQK-ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 171 GQVREQEGQVREQEGQVREQEG--------------------------------QMGEQE 198
++ EQ+ ++RE+E ++REQE ++ E+E
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 199 GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE------------EQMGEQEEQVQKQ 246
+M E+EE M EQEE+MQKQEE M EQEE+ +Q+ E+M EQEE++ +Q
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 516
Query: 247 EEQVQKQEE------------QMRKQEEQMREQEEQMREQEEQMLKQKEQTE-------- 286
EE+++ QEE +MR+QE+QM EQEE+MR+QE++M Q+E+ E
Sbjct: 517 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK 576
Query: 287 ----------QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
+EE+ E+E++MRE+EE MREQEE+M+EQEE+M+EQEE+M +QEE+M EQ
Sbjct: 577 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636
Query: 337 KEQMWEQKEQMWKQEEQMGEQ------------------EEQMQKQEEQVRKQEEQMRKQ 378
+E+MWEQ+E+MW+QEE+M EQ +E+MQ+QEE++ +QE+ +K
Sbjct: 637 EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Query: 379 EEQMRK--------QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
+EQ +K +EE MR++E++M E++E M EQ+E+M+EQEE+M EQ+E+M +QEE
Sbjct: 697 QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Query: 431 MGEQKE 436
M EQ+E
Sbjct: 757 MWEQEE 762
Score = 348 bits (892), Expect = 7e-96
Identities = 228/562 (40%), Positives = 353/562 (62%), Gaps = 131/562 (23%)
Query: 3 RITNEELKEKNAELQEELQLVETEKS----EIQLHIKELKRKLETDKIPLPQEGQVREQE 58
R +EL+E+ EL+E+ +L E E+ E ++ +E K + + +K+ QE ++ EQE
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM-WRQEERLWEQE 382
Query: 59 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG------------QVREQEGQVREQ 106
Q+REQE ++R+QE ++ EQ+ ++RE+E ++REQE +++EQE + R+Q
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 107 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ------VREQEGQVR 160
E +++E+E ++RE+E ++RE+E +REQE ++++QE + EQE + + EQ+ ++
Sbjct: 443 EEKMQEEE-RIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 161 EQEGQVREQEGQVREQEGQVREQE---GQ---------VREQEGQMGEQEGQMGEQEEQM 208
EQE +++EQE ++ EQE ++R+QE GQ +REQE QM EQE +M +QE++M
Sbjct: 502 EQE-KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 209 GEQEEQMQK-----------------QEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQ 251
+QEE+M+K +EE+M E+E++MR++EE M EQEE++Q+QEE++Q
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ--------------------------T 285
+QEE+M +QEE+M+EQEE+M EQEE+M +Q+E+
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 286 EQEEQTGEQ----------------------EEQMREQEEQMREQEEQMREQEEQMREQE 323
EQEE+ EQ EE MRE+E++MRE+EE MREQEE+M+EQE
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 324 EQMGKQEEQMWEQKEQMWEQKEQM-------------------------WKQEEQMGEQE 358
E+M +QEE+MWEQ+E+MWEQ+E+M W+QEE+M +QE
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE 800
Query: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE----QE 414
E+M+ QEE++R QEE+MR QEE+M QEE+M QEE+M Q+E+M Q+E+M E QE
Sbjct: 801 EKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQE 860
Query: 415 EQMGEQKEQMRKQEEHMGEQKE 436
E+M EQ+E+MR QEE M EQ+E
Sbjct: 861 EKMREQEEKMRGQEEKMREQEE 882
Score = 347 bits (889), Expect = 2e-95
Identities = 214/489 (43%), Positives = 338/489 (69%), Gaps = 60/489 (12%)
Query: 6 NEELKEKNAELQEELQLVE-TEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ 64
+E L+EK ++E+ ++ E EK + ++E ++K + + +E ++RE+E ++RE+
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 65 EGQVREQEGQVREQEGQVREQEGQ------VREQEGQVREQEGQVREQEGQVREQEGQVR 118
E +REQE ++++QE + EQE + + EQ+ ++ EQE +++EQE ++ EQE ++R
Sbjct: 463 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIWEQEEKIR 521
Query: 119 EQE---GQ---------VREQEGQVREQEGQVREQEGQVREQEGQV----REQEGQVREQ 162
+QE GQ +REQE Q+ EQE ++R+QE ++ +QE ++ +EQE + +Q
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581
Query: 163 EGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM 222
E ++RE+E ++RE+E ++RE+E +REQE +M EQE +M EQEE+M EQEE+MQ+QEE+M
Sbjct: 582 EEKMREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 223 GEQEEQMRKQEEQMGEQE---EQVQKQEEQVQKQE-EQMRKQEEQMREQEEQMREQEEQM 278
EQEE+M +QEE+M EQ+ EQ +K E + QE E+M++QEE++ EQE+ ++ +EQ
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 279 LK--QKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
K +E+ +EE E+E++MRE+EE MREQEE+M+EQEE+M+EQEE+M +QEE+MWEQ
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ 760
Query: 337 KEQMWEQK------------------EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378
+E+MWEQ+ E++W+QEE+M +QEE+M+ QEE++R QEE+MR Q
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ 820
Query: 379 EEQMRKQEEQMRKQEEQMGEQKEQM-GE----------QKEQMREQEEQMGEQKEQMRKQ 427
EE+M QEE+M QEE+M Q+E+M G+ Q+E+MREQEE+M Q+E+MR+Q
Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQ 880
Query: 428 EEHMGEQKE 436
EE M Q+E
Sbjct: 881 EEKMRGQEE 889
Score = 240 bits (612), Expect = 2e-63
Identities = 156/362 (43%), Positives = 259/362 (71%), Gaps = 26/362 (7%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKL-ETDKIPLPQEGQVREQEGQVREQE 65
E+++E+ ++ E+ + + ++ ++ + +++K E +K QE ++RE+E ++RE+E
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE-RMRERE 595
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
++RE+E +REQE +++EQE +++EQE ++ EQE +++EQE ++ EQE ++ EQE ++
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG---QVREQEGQVREQEGQVRE 182
EQ+ ++ EQ+ ++ E E +++EQE +++EQE ++ EQE + +EQE + +QE ++RE
Sbjct: 656 EQQ-RLPEQKEKLWEHE-KMQEQE-KMQEQEEKIWEQEKMEKKTQEQEKKTWDQE-KMRE 711
Query: 183 QEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE-- 240
+E +RE+E +M E+E M EQEE+M EQEE+MQ+QEE+M EQEE+M +QEE+M EQ+
Sbjct: 712 EES-MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRL 770
Query: 241 -EQVQK--------QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-EQEEQ 290
EQ +K ++E++ +QEE+MR QEE+MR QEE+MR QEE+M Q+E+ QEE+
Sbjct: 771 PEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Query: 291 TGEQEEQMREQEEQMREQEEQMRE----QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ 346
QEE+M QEE+M QEE+M E QEE+MREQEE+M QEE+M EQ+E+M Q+E+
Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Query: 347 MW 348
++
Sbjct: 891 IY 892
Score = 163 bits (413), Expect = 2e-40
Identities = 88/261 (33%), Positives = 179/261 (68%), Gaps = 13/261 (4%)
Query: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE---EQMGEQEEQMRKQEEQMGEQEE 241
G+ ++ G++ GE + + + +K + E++ ++ + + + + E
Sbjct: 162 GESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNE 221
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQ---MLKQKEQTEQEEQTGEQEEQM 298
+++K+ ++Q++ ++ +++ ++++ + E+ +L Q + +E+ QEE++
Sbjct: 222 ELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 281
Query: 299 REQEEQMREQEEQMREQEEQMREQEEQMGK---QEEQMWEQKEQMWEQKEQMWKQEEQMG 355
REQE+++R+QEE+M QEE++REQE GK QEE+MW Q++++ EQ++++ +QE+++
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQE---GKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 356 EQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415
EQ+E +++QEEQ+++QEE+M +QEE+MR+QEE+M +QEE++ EQ++QM EQ+++MR+QEE
Sbjct: 339 EQKE-LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 416 QMGEQKEQMRKQEEHMGEQKE 436
+M EQ E++R++EE M EQ++
Sbjct: 398 RMWEQDERLREKEERMREQEK 418
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 394 bits (1013), Expect = e-110
Identities = 219/450 (48%), Positives = 343/450 (76%), Gaps = 26/450 (5%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQE----- 58
IT+EELKEKNA+LQE+LQLVE+EKSEIQL++KELKRKLE K+ LPQ+ E +
Sbjct: 275 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 334
Query: 59 ---------GQVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 106
QV E E R +QE ++ QE +++E E +++EQE ++REQE ++REQ
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 394
Query: 107 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 166
E ++R QE + E+E ++R QE + E+E ++R QE + E+E ++RE E ++ EQE ++
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KI 453
Query: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE 226
REQE + R++E ++REQE + +EQE +M QE ++ EQEE++ EQEE+M +QEE++ EQE
Sbjct: 454 REQE-EKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE 511
Query: 227 ----EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
E+ R+++E+M QEE++++QEE + +Q+E++ +QEE++R+QEE+M QEE+M Q+
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEE-IWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 283 EQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
E+ EQEE+ QEE++REQEE++REQEE++REQEE +EQEE+MG+QEE+M EQ+E+M
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 630
Query: 342 EQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
EQ+E+M +QEE++ EQE+++++QEE++R+QEE M++QEE+M +QEE+M +QEE+M EQ+E
Sbjct: 631 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 690
Query: 402 QMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
+M Q+E+M EQE ++ +Q+E+M++ +EH+
Sbjct: 691 KMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 197 bits (500), Expect = 2e-50
Identities = 106/240 (44%), Positives = 176/240 (73%), Gaps = 4/240 (1%)
Query: 7 EELKEKNAEL--QEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ 64
E+++E+ ++ QEE + EK Q I+E +++ E +++ QE ++REQE ++ Q
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM-WRQEEKIREQE-EIWRQ 541
Query: 65 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
+ ++ EQE ++R+QE ++ QE ++ +QE ++REQE +V QE ++REQE ++REQE ++
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI 601
Query: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
REQE +EQE ++ EQE ++ EQE +++EQE ++R QE ++REQE ++REQE ++REQE
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Query: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
++EQE +M EQE +M EQEE+M EQEE+M++QEE+M EQE ++R+QEE+M E +E ++
Sbjct: 662 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 150 bits (378), Expect = 3e-36
Identities = 95/334 (28%), Positives = 201/334 (60%), Gaps = 29/334 (8%)
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
EQ+ + QE RE E QV +R Q E + + + V++ EG+ R+
Sbjct: 171 EQKASHQHQEALRRELEAQVHT----IRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 226
Query: 186 QVREQEGQMGEQE---GQMGEQEEQMGEQEEQMQKQEEQMGEQ-------EEQMRKQEEQ 235
++ + GE E + Q+++ E++ K+ + + + +E+++++ +
Sbjct: 227 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 286
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE--QEEQMREQEEQMLKQKEQTEQEEQTGE 293
+ E+ + V+ ++ ++Q ++++++ E+ + ++Q++ + + + K+ + + Q
Sbjct: 287 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 346
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
+E ++ + Q +QEE+M QEE+++E EE++ +QEE++ EQ+E++ EQ+E+M +QEE
Sbjct: 347 EENELWNRLNQ--QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 404
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ-----KEQMGEQKE 408
M E+EE+M++QEE + ++EE+MR+QEE M ++EE++R+ EE+M EQ +E+ +++E
Sbjct: 405 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 464
Query: 409 QMREQEE------QMGEQKEQMRKQEEHMGEQKE 436
++REQE+ +M Q+E++R+QEE + EQ+E
Sbjct: 465 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 498
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 390 bits (1003), Expect = e-108
Identities = 232/535 (43%), Positives = 357/535 (66%), Gaps = 105/535 (19%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ------------- 50
IT+EELKEKNA+LQE+LQLVE+EKSEIQL++KELKRKLE K+ LPQ
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
Query: 51 ---------------------------------------EGQVREQEGQVREQEGQVREQ 71
E +++EQE ++REQE ++REQ
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
Query: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 131
E ++R QE + E+E ++R QE + E+E ++R QE + E+E ++R QE + E+E ++
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
Query: 132 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 191
RE E ++ EQE ++REQE + R++E ++REQE + +EQE ++ QE ++REQE ++REQE
Sbjct: 394 RELEEKMHEQE-KIREQE-EKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQE 450
Query: 192 GQMGEQEGQMGEQE-----------EQMGEQEEQMQKQEE------QMGEQEEQMRKQEE 234
+M QE ++ EQE E+M QEE++ +QEE +M EQEE++RKQEE
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEE------------------------- 269
++ QEE++++QEE++++QEE+M +QEE++REQEE
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 270 -------QMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
++REQEE++ +Q+E+ EQEE+ EQEE+M +QEE++REQEE+++EQEE++RE
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
Query: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ 381
QEE++ +QEE EQ+E+M EQ+E+M +QEE+M EQEE M +QEE++R+QE+++R+QEE+
Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690
Query: 382 MRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+R+QEE M++QEE+M EQ+E+M EQ+E+M+EQEE+M Q+E+M +QE + +Q+E
Sbjct: 691 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Score = 340 bits (872), Expect = 1e-93
Identities = 192/448 (42%), Positives = 330/448 (73%), Gaps = 26/448 (5%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRK----LETDKIPLPQEGQVREQEGQVR 62
E+++E ++QE+ + + ++ +I+ ++++R+ E ++ QE + E+E ++R
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122
QE + E+E ++R QE + E+E ++RE E ++ EQE ++REQE + R++E ++REQE
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQE-EKRQEEEKIREQEK 424
Query: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE------------QE 170
+ +EQE ++ QE ++REQE ++REQE ++ QE ++ EQE ++RE QE
Sbjct: 425 R-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQE 482
Query: 171 GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR 230
++ EQE ++ Q+ ++ EQE ++ +QE ++ QEE++ EQEE++++QEE+M QEE++R
Sbjct: 483 EKIHEQE-EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 231 KQEEQMGEQEEQVQK----QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE-QT 285
+QEE E+E+ ++ +EE+ Q+QE++M +QEE++REQEE++ QEE++ +Q+E +
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
Query: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345
EQEE+ +QEE++REQEE+++EQEE++REQEE++REQEE +QEE+M EQ+E+M EQ+E
Sbjct: 602 EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
Query: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE 405
+M +QEE M QEE++++QE+++R+QEE++R+QEE M++QEE+M +QEE+M EQ+E+M E
Sbjct: 662 KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
Query: 406 QKEQMREQEEQMGEQKEQMRKQEEHMGE 433
Q+E+MR QEE+M EQ+ ++R+QEE M E
Sbjct: 722 QEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 337 bits (863), Expect = 2e-92
Identities = 195/435 (44%), Positives = 329/435 (75%), Gaps = 20/435 (4%)
Query: 3 RITNEELKEKNAEL--QEELQLVETEKSEIQLHI---KELKRKLETDKIPLPQEGQVREQ 57
R E+++E+ ++ QEE+ + EK Q + KE K + + +++ +E ++R Q
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKMRRQ 382
Query: 58 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 117
E + E+E ++RE E ++ EQE ++REQE + R++E ++REQE + +EQE ++ QE ++
Sbjct: 383 EEMMWEKEEKIRELEEKMHEQE-KIREQE-EKRQEEEKIREQEKR-QEQEAKMWRQEEKI 439
Query: 118 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 177
REQE ++REQE ++ QE ++ EQE ++RE+E + +EQE R++E ++ EQE ++ Q+
Sbjct: 440 REQEEKIREQEKKMWRQEEKIHEQE-KIREEEKR-QEQEEMWRQEE-KIHEQE-EIWRQK 495
Query: 178 GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG 237
++ EQE ++R+QE ++ QE ++ EQEE++ EQEE+M +QEE++ EQEE M ++EE+M
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWREEEKMH 554
Query: 238 EQ-----EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-EQEEQT 291
EQ EE+ Q+QE+++ +QEE++R+QEE++ QEE++REQEE+ +Q+E+ +QEE+
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 292 GEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
EQEE+++EQEE++REQEE++REQEE +EQEE+MG+QEE+M EQ+E+M EQ+E MW+QE
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
E++ EQE+++++QEE++R+QEE M++QEE+M +QEE+M +QEE+M EQ+E+M Q+E+M
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
Query: 412 EQEEQMGEQKEQMRK 426
EQE ++ +Q+E+M++
Sbjct: 735 EQEVRLRQQEEKMQE 749
Score = 193 bits (490), Expect = 3e-49
Identities = 142/458 (31%), Positives = 256/458 (55%), Gaps = 39/458 (8%)
Query: 2 PRITNEELKEKNAELQEEL--QLVETEKSEIQLHIKELKRKLETDKIP-LPQEGQVREQE 58
P ++ E + K AE +E+L +T S K+K+ P G E
Sbjct: 49 PMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPE 108
Query: 59 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 118
EQ+ + QE RE E QV +R Q E + + + V++ EG+ R
Sbjct: 109 D---EQKASHQHQEALRRELEAQVHT----IRILTCQKTELQMALYYSQHAVKQLEGEAR 161
Query: 119 EQEGQVREQ---EGQVREQEGQVREQEGQV-REQEGQVREQEGQVRE-QEGQVREQEGQV 173
+ ++ + G++ + V Q+ + R E +E++ E + ++E +
Sbjct: 162 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
Query: 174 REQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE 233
+ + Q + Q + + E Q+ +E + + ++ ++Q+Q + + +G++ + + +
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
Query: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293
+ E+ E + +Q QEE+M +QEE+++E EE+++EQEE++ EQEE+ E
Sbjct: 282 QAQVEENELWNRLNQQ---QEEKMWRQEEKIQEWEEKIQEQEEKI------REQEEKIRE 332
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
QEE+MR QEE M E+EE+MR QEE M E+EE+M +QEE MWE++E+M Q+E MW++EE+
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Query: 354 MGEQEEQMQKQE-----EQVRKQEEQMRKQEE------QMRKQEEQMRKQEEQMGEQKEQ 402
+ E EE+M +QE E+ R++EE++R+QE+ +M +QEE++R+QEE++ EQ+++
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
Query: 403 MGEQKEQMREQ----EEQMGEQKEQMRKQEEHMGEQKE 436
M Q+E++ EQ EE+ +++E+M +QEE + EQ+E
Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 384 bits (987), Expect = e-107
Identities = 221/455 (48%), Positives = 344/455 (75%), Gaps = 28/455 (6%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQE----- 58
IT+EELKEKNA+LQE+LQLVE+EKSEIQL++KELKRKLE K+ LPQ+ E +
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
Query: 59 ---------GQVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 106
QV E E R +QE ++ QE +++E E +++EQE ++REQE ++REQ
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
Query: 107 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 166
E ++R QE + E+E ++R QE + E+E ++R E + E+E ++RE E ++ EQE ++
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE-KI 392
Query: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE 226
REQE + R++E ++REQE + +EQE +M QE ++ EQEE++ EQE++M +QEE++ EQE
Sbjct: 393 REQE-EKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 450
Query: 227 ----EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
E+ R+++E+M QEE++++QEE + +Q+E+M +QE+ +R+QEE++ QEE+M Q+
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIREQEE-IWRQKEKMHEQEK-IRKQEEKVWRQEEKMHDQE 508
Query: 283 EQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
E+ EQEE+ QEE++REQEE++REQEE++REQEE M+EQEE+MG+QEE+M EQ E+M
Sbjct: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMR 567
Query: 342 EQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
Q+E++ +QEE++ EQ+E++++QEE++ +QEE++R+QEE M++QEE+M +QEE+M EQ+E
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 402 QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+M EQ+E+MR QEE+M EQ+ ++R+QEE M E +E
Sbjct: 628 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 332 bits (852), Expect = 3e-91
Identities = 207/495 (41%), Positives = 322/495 (65%), Gaps = 98/495 (19%)
Query: 15 ELQEEL-------------------------------------------------QLVET 25
EL++ L QLVE+
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 26 EKSEIQLHIKELKRKLETDKIPLPQ---------------------EGQVRE-------- 56
EKSEIQL++KELKRKLE K+ LPQ + QV E
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 57 ---------QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 107
QE +++E E +++EQE ++REQE ++REQE ++R QE + E+E ++R QE
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
Query: 108 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
+ E+E ++R E + E+E ++RE E ++ EQE ++REQE + R++E ++REQE + +
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE-KIREQE-EKRQEEEKIREQEKR-Q 412
Query: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ----EEQMGEQEEQMQKQEEQMG 223
EQE ++ QE ++REQE ++REQE +M QE ++ EQ EE+ +++E+M +QEE++
Sbjct: 413 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 472
Query: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283
EQEE R Q+E+M EQ E+++KQEE+V +QEE+M QEE++REQEE+M QEE++ +Q+E
Sbjct: 473 EQEEIWR-QKEKMHEQ-EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE 530
Query: 284 Q-TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
+ EQEE+ EQEE M+EQEE+M EQEE+M+EQ E+MR QEE++ +QEE++ EQKE++ E
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEKIREQKEKIRE 589
Query: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402
Q+E++W+QEE++ EQEE MQ+QEE++ +QEE+M +QEE+M++QEE+MR+QEE+M EQ+ +
Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 649
Query: 403 MGEQKEQMREQEEQM 417
+ +Q+E+M+E +E +
Sbjct: 650 LRQQEEKMQEHQEHL 664
Score = 214 bits (544), Expect = 2e-55
Identities = 124/285 (43%), Positives = 208/285 (72%), Gaps = 14/285 (4%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E+++E+ + QEE ++ E EK + Q E K + +KI QE ++REQE ++ QE
Sbjct: 390 EKIREQEEKRQEEEKIREQEKRQEQ----EAKMWRQEEKIR-EQEEKIREQEKKMWRQEE 444
Query: 67 QVREQEGQVREQEGQVRE-----QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
++ EQE ++RE+E + + QE ++REQE ++ Q+ ++ EQE ++R+QE +V QE
Sbjct: 445 KIHEQE-KIREEEKRQEQEEMWRQEEKIREQE-EIWRQKEKMHEQE-KIRKQEEKVWRQE 501
Query: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
++ +QE ++REQE ++ QE ++REQE ++REQE ++REQE ++EQE ++ EQE +++
Sbjct: 502 EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ 561
Query: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
EQE ++R QE ++ EQE ++ EQ+E++ EQEE++ +QEE++ EQEE M++QEE+M EQEE
Sbjct: 562 EQE-KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286
++ +QEE++Q+QEE+MR+QEE+M EQE ++R+QEE+M + +E E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 146 bits (369), Expect = 3e-35
Identities = 93/328 (28%), Positives = 198/328 (60%), Gaps = 24/328 (7%)
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
EQ+ + QE RE E QV +R Q E + + + V++ EG+ R+
Sbjct: 110 EQKASHQHQEALRRELEAQVHT----IRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
Query: 186 QVREQEGQMGEQE---GQMGEQEEQMGEQEEQMQKQEEQMGEQ-------EEQMRKQEEQ 235
++ + GE E + Q+++ E++ K+ + + + +E+++++ +
Sbjct: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE--QEEQMREQEEQMLKQKEQTEQEEQTGE 293
+ E+ + V+ ++ ++Q ++++++ E+ + ++Q++ + + + K+ + + Q
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
+E ++ + Q +QEE+M QEE+++E EE++ +QEE++ EQ+E++ EQ+E+M +QEE
Sbjct: 286 EENELWNRLNQ--QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ-----KEQMGEQKE 408
M E+EE+M++QEE + ++EE+MR+ EE M ++EE++R+ EE+M EQ +E+ +++E
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 403
Query: 409 QMREQEEQMGEQKEQMRKQEEHMGEQKE 436
++REQE++ EQ+ +M +QEE + EQ+E
Sbjct: 404 KIREQEKRQ-EQEAKMWRQEEKIREQEE 430
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 344 bits (882), Expect = 1e-94
Identities = 189/377 (50%), Positives = 288/377 (76%), Gaps = 19/377 (5%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63
IT+EELKEKNA+LQE+LQLVE+EKSEIQL++KELKRKLE K+ LPQ+ E + +E
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 261
Query: 64 QEGQVREQEGQVRE----------QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 113
+ + + QV E QE ++ QE +++E+E +++EQE ++REQE ++R Q
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 173
E + E+E ++R QE + E+E ++RE E ++ EQE ++REQE + R++E ++REQE +
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQE-EKRQEEEKIREQEKR- 378
Query: 174 REQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE 233
+EQE ++ QE ++REQE ++ EQE M EQEE+MGEQEE+M +QEE+M EQEE+MR+QE
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293
E++ EQE+++++QEE++++QEE M++QEE+M EQE +M EQE +M EQEE+
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM------QEQEEKMRR 492
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
QEE++REQE+++REQEE++REQEE M+EQEE+M +QEE+M EQ+E+M EQ+E+M +QEE+
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 354 MGEQEEQMQKQEEQVRK 370
M EQE ++++QEE++++
Sbjct: 553 MREQEVRLRQQEEKMQE 569
Score = 300 bits (767), Expect = 2e-81
Identities = 172/423 (40%), Positives = 297/423 (70%), Gaps = 22/423 (5%)
Query: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQ 74
EL++ L V T+K + +I+EL ++ + + L + E+ ++E+ +
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE----------LKEKNAK 213
Query: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134
++E+ V ++ +++ V+E + ++ + + +Q+ Q E + +E + +
Sbjct: 214 LQEKLQLVESEKSEIQLN---VKELKRKLERAKLLLPQQQLQA-EADHLGKELQSVSAKL 269
Query: 135 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQM 194
+ QV E E R + +QE ++ QE +++E+E +++EQE ++REQE ++R QE M
Sbjct: 270 QAQVEENELWNRLNQ----QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325
Query: 195 GEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE 254
E+E +M QEE M E+EE++++ EE+M EQE+ +R+QEE+ QEE+ +++E+ Q+QE
Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-IREQEEK--RQEEEKIREQEKRQEQE 382
Query: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMR 313
+M +QEE++REQEE++REQEE M +Q+E+ EQEE+ EQEE+M+EQEE+MR QEE++R
Sbjct: 383 AKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIR 442
Query: 314 EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373
EQE+++REQEE++ +QEE M EQ+E+M EQ+ +M +QE +M EQEE+M++QEE++R+QE+
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502
Query: 374 QMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
++R+QEE++R+QEE M++QEE+M EQ+E+M EQ+E+M+EQEE+M Q+E+MR+QE + +
Sbjct: 503 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQ 562
Query: 434 QKE 436
Q+E
Sbjct: 563 QEE 565
Score = 164 bits (414), Expect = 2e-40
Identities = 102/355 (28%), Positives = 204/355 (57%), Gaps = 50/355 (14%)
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
EQ+ + QE RE E QV+ +R Q E + + + V++ EG+ R+
Sbjct: 98 EQKASHQHQEALRRELEAQVQT----IRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 153
Query: 186 QVREQEGQMGEQE---GQMGEQEEQMGEQEEQMQKQEEQMGEQ-------EEQMRKQEEQ 235
++ + GE E + Q+++ E++ K+ + + + +E+++++ +
Sbjct: 154 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 213
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE--QEEQMREQEEQMLKQKEQTEQEEQTGE 293
+ E+ + V+ ++ ++Q ++++++ E+ + ++Q++ + + + K+ + + Q
Sbjct: 214 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
+E ++ + Q +QEE+M QEE+++E+EE++ +QEE++ EQ+E+M Q+E MW++EE+
Sbjct: 274 EENELWNRLNQ--QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331
Query: 354 MGEQEEQMQKQEEQVRKQEEQMR--------------------------------KQEEQ 381
M QEE M ++EE++R+ EE+M +QEE+
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 382 MRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+R+QEE++R+QEE M EQ+E+MGEQ+E+M EQEE+M EQ+E+MR+QEE + EQ++
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 319 bits (818), Expect = 3e-87
Identities = 178/420 (42%), Positives = 292/420 (69%), Gaps = 50/420 (11%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63
IT+EELKEKNAELQE+L+LVE+EKSEIQL++K+LKRKLE ++ LPQ+ E + +E
Sbjct: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
Query: 64 QEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
+ + + QV E E + +Q QE
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQ----------------------------------QE 296
Query: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
++ QE +++EQE ++ EQE ++REQE ++ QE ++ EQE ++REQE ++ QE ++R
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR 356
Query: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
EQE ++REQE +M QE ++ EQ+E++ EQEE+M +QEE++ EQEE K++E+M QE+
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEK 413
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
++++Q+E++++QEE+M +QEE++RE EE M++QEE++ E EE+ E+EE+M+EQ
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL------REVEEKMQEEEEKMQEQ 467
Query: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
EE+++ QEE+++EQEE+ QE+ + KQEE++WEQ+E+MW Q+E+MW+QEE+M EQEE+M
Sbjct: 468 EEKIQRQEEKIQEQEEKTWRQEKLL-KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Q+QEE++R+QE ++ +QEE+M++QE ++++ EE++G ++G++ E + + G Q+
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG----KLGQKAELLGGAGRESGSQR 582
Score = 266 bits (681), Expect = 2e-71
Identities = 152/398 (38%), Positives = 279/398 (70%), Gaps = 38/398 (9%)
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
+++E+ +++E+ +R E + E + V++ + ++ + + +Q+ QV E + +E
Sbjct: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
Query: 127 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
+ + + QV E E ++QE ++ QE +++EQE ++ EQE ++REQE ++ Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
E ++ EQE ++ EQE +M QEE++ EQEE++++QEE+M QEE++R+Q+E++ EQEE++
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 244 QKQEEQVQKQE----EQMRKQEEQMREQEEQMREQEEQMLKQKEQ-TEQEEQTGEQEEQM 298
+QEE++++QE E+M +QE++MREQ+E++REQEE+M +Q+E+ E EE +QEE++
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW------EQKEQMWEQKEQMWKQEE 352
RE EE+M+E+EE+M+EQEE+++ QEE++ +QEE+ W +Q+E++WEQ+E+MW+QEE
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Query: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE--QKEQM 410
+M EQEE+MQ+QEE++++QEE+MR+QE ++ +QEE+M++QE ++ E +E++G+ QK ++
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 411 -----RE-------------QEEQMGEQKEQMRKQEEH 430
RE Q E ++ + +++Q++H
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608
Score = 260 bits (665), Expect = 1e-69
Identities = 146/359 (40%), Positives = 259/359 (72%), Gaps = 17/359 (4%)
Query: 81 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 140
+++E+ +++E+ +R E + E + V++ + ++ + + +Q+ QV E + +E
Sbjct: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
Query: 141 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ 197
+ + + QV E E ++QE ++ QE +++EQE ++ EQE ++REQE +M Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257
E +M EQEE++ EQE++M +QEE++ EQEE++R+QEE+M QEE++++Q+E++Q+QEE+M
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317
+QEE++REQEE+ +Q++ QE++ EQ+E++REQEE+M QEE++RE EE
Sbjct: 391 WRQEEKIREQEEK---------RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 318 QMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
M++QEE++ + EE+M E++E+M EQ+E++ +QEE++ EQEE+ +QE+ + KQEE++ +
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL-KQEEKIWE 500
Query: 378 QEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
QEE+M +QEE+M +QEE+M EQ+E+M Q+E+MREQE ++ +Q+E+M++QE + E +E
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 198 bits (504), Expect = 7e-51
Identities = 116/329 (35%), Positives = 217/329 (65%), Gaps = 11/329 (3%)
Query: 7 EELKEKNAEL-QEELQLVETE----KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61
E+++E+ ++ ++EL++ E E + E ++H +E K + + DK+ QE ++REQE ++
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM-WRQEEKIREQEEKI 362
Query: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE----QEGQVREQEGQV 117
REQE ++ QE ++REQ+ +++EQE ++ QE ++REQE + +E QE ++REQ+ ++
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI 422
Query: 118 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 177
REQE ++ QE ++RE E +++QE ++RE E +++E+E +++EQE +++ QE +++EQE
Sbjct: 423 REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQE 482
Query: 178 GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG 237
+ QE ++ +QE ++ EQE +M QEE+M EQEE+MQ+QEE+M QEE+MR+QE ++
Sbjct: 483 EKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 238 EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
+QEE++Q+QE ++Q+ EE++ K ++ RE Q L Q E ++ +
Sbjct: 542 QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
Query: 298 MREQEEQMREQEEQMREQEEQMREQEEQM 326
+++Q++ R +Q +Q+ +E +
Sbjct: 602 LQQQQDHYRGHLQQYVAAYQQLASGKEAL 630
Score = 172 bits (437), Expect = 4e-43
Identities = 92/236 (38%), Positives = 163/236 (69%), Gaps = 4/236 (1%)
Query: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
+E++ E+ ++Q++ + ++ +++ + + + E+ Q Q Q Q E R +E
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272
Query: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324
+ + EE L +QEE+ QEE+++EQEE+M EQE ++REQEE+M QEE
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332
Query: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384
+M +QEE++ EQ+++MW Q+E++ +QEE++ EQEE+M +QEE++R+Q+E++++QEE+M +
Sbjct: 333 KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392
Query: 385 QEEQMRKQE----EQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
QEE++R+QE E+M Q+++M EQ E++REQEE+M Q+E++R+ EE M +Q+E
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Score = 160 bits (405), Expect = 2e-39
Identities = 108/421 (25%), Positives = 242/421 (57%), Gaps = 23/421 (5%)
Query: 22 LVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 81
++ E S++ HI +L+++ K+ G+ RE+ E+ Q+ E E +
Sbjct: 24 VLSDEDSDLDFHINKLEQQ---SKVRNKGHGKPREKS-IADEKFFQLSEMEAYLEN---- 75
Query: 82 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 141
R++ G R E E+ ++ + ++ + + E V++ +V+
Sbjct: 76 -RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSS 134
Query: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201
++++ ++ E+ R++ +++ ++ E Q R + + +E + +M
Sbjct: 135 ---FKKRQEKMNEKNYTFRKRV-VIKKPWLRLGEVTAQKRPENSLL--EETLHFDHAVRM 188
Query: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
G E++ ++ + + + +E+++++ ++ E+ V+ ++ ++Q + ++++
Sbjct: 189 GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
Query: 262 E--QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
E Q+ ++Q++ + +++ K+ + + Q +E ++ Q +QEE+M QEE++
Sbjct: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQEEKI 306
Query: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
+EQEE+M +QE ++ EQ+E+MW Q+E+M +QEE++ EQE++M +QEE++R+QEE++R+QE
Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE 366
Query: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE----EQMGEQKEQMRKQEEHMGEQK 435
E+M +QEE++R+Q+E++ EQ+E+M Q+E++REQE E+M Q+++MR+Q+E + EQ+
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 436 E 436
E
Sbjct: 427 E 427
Score = 114 bits (286), Expect = 1e-25
Identities = 73/276 (26%), Positives = 167/276 (60%), Gaps = 21/276 (7%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKL-ETDKIPLPQEGQVREQEGQVREQE 65
E+++E++ ++QE+ + + ++ +I+ ++ + K+ +K Q+ ++REQE ++ QE
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ------VRE 119
++RE E +++QE ++RE E +++E+E +++EQE +++ QE +++EQE + + +
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 179
QE ++ EQE ++ QE ++ EQE +++EQE +++ QE ++REQE ++ +QE +++EQE +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ---------EEQMQKQEEQ-MGEQEEQM 229
++E E E+ G++G++ +G + G Q + +++ QE Q + +Q++
Sbjct: 554 LQELE----ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHY 609
Query: 230 RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
R +Q +Q+ +E + + + + +R
Sbjct: 610 RGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLR 645
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 319 bits (818), Expect = 3e-87
Identities = 178/420 (42%), Positives = 292/420 (69%), Gaps = 50/420 (11%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63
IT+EELKEKNAELQE+L+LVE+EKSEIQL++K+LKRKLE ++ LPQ+ E + +E
Sbjct: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
Query: 64 QEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
+ + + QV E E + +Q QE
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQ----------------------------------QE 296
Query: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
++ QE +++EQE ++ EQE ++REQE ++ QE ++ EQE ++REQE ++ QE ++R
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR 356
Query: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
EQE ++REQE +M QE ++ EQ+E++ EQEE+M +QEE++ EQEE K++E+M QE+
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEK 413
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
++++Q+E++++QEE+M +QEE++RE EE M++QEE++ E EE+ E+EE+M+EQ
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL------REVEEKMQEEEEKMQEQ 467
Query: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
EE+++ QEE+++EQEE+ QE+ + KQEE++WEQ+E+MW Q+E+MW+QEE+M EQEE+M
Sbjct: 468 EEKIQRQEEKIQEQEEKTWRQEKLL-KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Q+QEE++R+QE ++ +QEE+M++QE ++++ EE++G ++G++ E + + G Q+
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG----KLGQKAELLGGAGRESGSQR 582
Score = 266 bits (681), Expect = 2e-71
Identities = 152/398 (38%), Positives = 279/398 (70%), Gaps = 38/398 (9%)
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
+++E+ +++E+ +R E + E + V++ + ++ + + +Q+ QV E + +E
Sbjct: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
Query: 127 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
+ + + QV E E ++QE ++ QE +++EQE ++ EQE ++REQE ++ Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
E ++ EQE ++ EQE +M QEE++ EQEE++++QEE+M QEE++R+Q+E++ EQEE++
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 244 QKQEEQVQKQE----EQMRKQEEQMREQEEQMREQEEQMLKQKEQ-TEQEEQTGEQEEQM 298
+QEE++++QE E+M +QE++MREQ+E++REQEE+M +Q+E+ E EE +QEE++
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW------EQKEQMWEQKEQMWKQEE 352
RE EE+M+E+EE+M+EQEE+++ QEE++ +QEE+ W +Q+E++WEQ+E+MW+QEE
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Query: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE--QKEQM 410
+M EQEE+MQ+QEE++++QEE+MR+QE ++ +QEE+M++QE ++ E +E++G+ QK ++
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 411 -----RE-------------QEEQMGEQKEQMRKQEEH 430
RE Q E ++ + +++Q++H
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608
Score = 260 bits (665), Expect = 1e-69
Identities = 146/359 (40%), Positives = 259/359 (72%), Gaps = 17/359 (4%)
Query: 81 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 140
+++E+ +++E+ +R E + E + V++ + ++ + + +Q+ QV E + +E
Sbjct: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
Query: 141 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ 197
+ + + QV E E ++QE ++ QE +++EQE ++ EQE ++REQE +M Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257
E +M EQEE++ EQE++M +QEE++ EQEE++R+QEE+M QEE++++Q+E++Q+QEE+M
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317
+QEE++REQEE+ +Q++ QE++ EQ+E++REQEE+M QEE++RE EE
Sbjct: 391 WRQEEKIREQEEK---------RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 318 QMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
M++QEE++ + EE+M E++E+M EQ+E++ +QEE++ EQEE+ +QE+ + KQEE++ +
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL-KQEEKIWE 500
Query: 378 QEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
QEE+M +QEE+M +QEE+M EQ+E+M Q+E+MREQE ++ +Q+E+M++QE + E +E
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 198 bits (504), Expect = 7e-51
Identities = 116/329 (35%), Positives = 217/329 (65%), Gaps = 11/329 (3%)
Query: 7 EELKEKNAEL-QEELQLVETE----KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61
E+++E+ ++ ++EL++ E E + E ++H +E K + + DK+ QE ++REQE ++
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM-WRQEEKIREQEEKI 362
Query: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE----QEGQVREQEGQV 117
REQE ++ QE ++REQ+ +++EQE ++ QE ++REQE + +E QE ++REQ+ ++
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI 422
Query: 118 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 177
REQE ++ QE ++RE E +++QE ++RE E +++E+E +++EQE +++ QE +++EQE
Sbjct: 423 REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQE 482
Query: 178 GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG 237
+ QE ++ +QE ++ EQE +M QEE+M EQEE+MQ+QEE+M QEE+MR+QE ++
Sbjct: 483 EKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 238 EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
+QEE++Q+QE ++Q+ EE++ K ++ RE Q L Q E ++ +
Sbjct: 542 QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
Query: 298 MREQEEQMREQEEQMREQEEQMREQEEQM 326
+++Q++ R +Q +Q+ +E +
Sbjct: 602 LQQQQDHYRGHLQQYVAAYQQLASGKEAL 630
Score = 172 bits (437), Expect = 4e-43
Identities = 92/236 (38%), Positives = 163/236 (69%), Gaps = 4/236 (1%)
Query: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
+E++ E+ ++Q++ + ++ +++ + + + E+ Q Q Q Q E R +E
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272
Query: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324
+ + EE L +QEE+ QEE+++EQEE+M EQE ++REQEE+M QEE
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332
Query: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384
+M +QEE++ EQ+++MW Q+E++ +QEE++ EQEE+M +QEE++R+Q+E++++QEE+M +
Sbjct: 333 KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392
Query: 385 QEEQMRKQE----EQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
QEE++R+QE E+M Q+++M EQ E++REQEE+M Q+E++R+ EE M +Q+E
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Score = 162 bits (409), Expect = 7e-40
Identities = 108/421 (25%), Positives = 243/421 (57%), Gaps = 23/421 (5%)
Query: 22 LVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 81
++ E S++ HI +L+++ K+ G+ RE+ E+ Q+ E E +
Sbjct: 24 VLSDEDSDLDFHINKLEQQ---SKVRNKGHGKPREKS-IADEKFFQLSEMEAYLEN---- 75
Query: 82 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 141
R++ G R E E+ ++ + ++ + + E V++ +V+
Sbjct: 76 -RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSS 134
Query: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201
++++ ++ E+ R++ +++ ++ E Q R + + +E + +M
Sbjct: 135 ---FKKRQEKMNEKNYTFRKRV-VIKKPWLRLGEVTAQKRPENSLL--EETLHFDHAVRM 188
Query: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
G E++ ++ + + + + +E+++++ ++ E+ V+ ++ ++Q + ++++
Sbjct: 189 GTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
Query: 262 E--QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
E Q+ ++Q++ + +++ K+ + + Q +E ++ Q +QEE+M QEE++
Sbjct: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQEEKI 306
Query: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
+EQEE+M +QE ++ EQ+E+MW Q+E+M +QEE++ EQE++M +QEE++R+QEE++R+QE
Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE 366
Query: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE----EQMGEQKEQMRKQEEHMGEQK 435
E+M +QEE++R+Q+E++ EQ+E+M Q+E++REQE E+M Q+++MR+Q+E + EQ+
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 436 E 436
E
Sbjct: 427 E 427
Score = 114 bits (286), Expect = 1e-25
Identities = 73/276 (26%), Positives = 167/276 (60%), Gaps = 21/276 (7%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKL-ETDKIPLPQEGQVREQEGQVREQE 65
E+++E++ ++QE+ + + ++ +I+ ++ + K+ +K Q+ ++REQE ++ QE
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ------VRE 119
++RE E +++QE ++RE E +++E+E +++EQE +++ QE +++EQE + + +
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 179
QE ++ EQE ++ QE ++ EQE +++EQE +++ QE ++REQE ++ +QE +++EQE +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ---------EEQMQKQEEQ-MGEQEEQM 229
++E E E+ G++G++ +G + G Q + +++ QE Q + +Q++
Sbjct: 554 LQELE----ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHY 609
Query: 230 RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
R +Q +Q+ +E + + + + +R
Sbjct: 610 RGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLR 645
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 214 bits (544), Expect = 2e-55
Identities = 141/479 (29%), Positives = 294/479 (61%), Gaps = 52/479 (10%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKR----------KLETDKIPLPQEGQVRE 56
+E +EK + ELQ E E++ Q +E +R K E + L +RE
Sbjct: 733 QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE 792
Query: 57 Q-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV--REQEGQVREQ 113
Q E Q+R +E Q REQ E+E + R ++ + RE+E Q E+E Q+ RE+ Q++E+
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE 852
Query: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ---------EGQVREQEGQVREQEG 164
E ++E + + R QE Q R+Q+ + + +E + R + + Q+R+++ ++E+E
Sbjct: 853 EDGLQEDQERRRSQE-QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 165 QVREQEGQVR---EQEGQVREQEGQVREQEGQMGEQEGQMG---EQEEQMGEQEEQMQKQ 218
+++ +E + R EQE Q RE+E Q++++E Q+ +E + E+E Q + ++ QK+
Sbjct: 912 ELQREEREKRRRQEQERQYREEE-QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 219 EEQMGEQEEQMRKQE-EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE--QEEQMREQE 275
E+ +GE+ E+ R+QE E+ +EE++Q++EEQ+ ++E + R+++E R+ ++++++++E
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1030
Query: 276 EQMLKQKEQ----TEQEEQTGEQEEQMREQEEQMREQEEQMREQE-EQMREQEEQMGKQE 330
EQ+L+++ + E+E Q E+EE +E+E+ + E+ E R QE E+ +EE++ ++E
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090
Query: 331 EQMW--EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVR---------KQEEQMRKQE 379
EQ+ E +++ +++E+ ++EE++ ++EEQ+ ++E + R ++EE+++++E
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Query: 380 EQMRKQEEQMRKQEE---QMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
EQ+ ++E + R+++E Q E++E E+++ +RE++E+ +++E+ ++EE + QK
Sbjct: 1151 EQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 206 bits (525), Expect = 3e-53
Identities = 145/458 (31%), Positives = 285/458 (62%), Gaps = 44/458 (9%)
Query: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
R E+L+E+ + Q ELQ E E+ +L +EL+R+ + ++ Q+ ++R ++ R
Sbjct: 254 RKEEEKLQEEEPQRQRELQ--EEEEQLRKLERQELRRERQEEE---QQQQRLRREQQLRR 308
Query: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122
+QE + REQ+ + REQ+ + REQ+ + REQ Q+R ++ + REQ+ + REQE + REQ+
Sbjct: 309 KQEEERREQQEERREQQER-REQQEERREQ--QLRREQEERREQQLR-REQEEERREQQL 364
Query: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ----EG 178
+ REQE + REQ Q+R ++ REQ Q+R ++ REQ Q+R ++ REQ E
Sbjct: 365 R-REQEEERREQ--QLRREQQLRREQ--QLRREQQLRREQ--QLRREQQLRREQQLRREQ 417
Query: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ---KQEEQMGEQEEQMRKQEEQ 235
Q+R ++ REQE + EQ+ + +E+++ ++E+ + K+EE+ E++ RKQ+ +
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477
Query: 236 MGEQEE--------QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
++EE + +++ EQ +++E+Q+R+++E+ REQ + R++EE+ L+Q+ ++EQ
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK-RQEEEERLQQRLRSEQ 536
Query: 288 E---EQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ--KEQMWE 342
+ EQ +E+ ++ +EE+ EQE + + + + E+ +Q+ K+EE+ +Q K + E
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 343 QKEQMWKQEE----QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
+ EQ K+EE + E+ EQ K+EE ++ +Q+ K EEQ ++++Q+R+++++ E
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Query: 399 QKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Q+ + E++E++ E+++ + E+ R+++E E++E
Sbjct: 657 QRLKREEEEERL---EQRLKREHEEERREQELAEEEQE 691
Score = 204 bits (518), Expect = 2e-52
Identities = 138/472 (29%), Positives = 281/472 (59%), Gaps = 67/472 (14%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
+EK A + L++ + E E +R+ E P++ Q+ E+ GQ R Q+ Q
Sbjct: 97 EEKRARCDGKESLLQDRRQE------EDQRRFE------PRDRQLEEEPGQRRRQKRQ-- 142
Query: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
EQE ++ E E Q +QE ++ +++ Q R++E + QE Q RE+ EQ + E
Sbjct: 143 EQERELAEGEEQSEKQE-RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET 201
Query: 130 QVREQEGQVR-------------EQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVR 174
+ E Q+R E++ Q RE++ +V E+E + R++E +R++E +++
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 175 EQEGQ----VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ-KQEEQMGEQEEQM 229
E+E Q ++E+E Q+R+ E Q +E Q EQ++Q +E+Q++ KQEE+ EQ+E+
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 230 RKQEEQMGEQEE---------QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE----- 275
R+Q+E+ +QEE Q +++E+Q+++++E+ R++++ REQEE+ REQ+
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 276 ----EQMLKQKEQTEQEEQTGEQEEQMREQ----EEQMREQEEQMREQEEQMREQEEQMG 327
EQ L++++Q +E+Q +++ REQ E+Q+R +++ REQEE+ EQ+ +
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Query: 328 KQEEQMWEQKEQM--WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQ 385
++E+++ ++E+ W ++E+ ++ EQ E+ +Q K++++ ++E ++ +EE+ R+Q
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQ--ERRKQQLKRDQEEERRERWLKLEEEERREQ 499
Query: 386 EEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ---KEQMRKQEEHMGEQ 434
+E ++E+Q+ ++E+ EQ+ + +E+EE++ ++ ++Q+R+++E EQ
Sbjct: 500 QE---RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Score = 202 bits (514), Expect = 5e-52
Identities = 135/467 (28%), Positives = 284/467 (60%), Gaps = 42/467 (8%)
Query: 1 MPRITNEELKEKNAELQEELQLVETEKSEI-----QLHIKELKRKLETDKIPLPQEGQVR 55
+ R EE +E+ +E+ Q E KS I QL + R+ + P QEGQ R
Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR 731
Query: 56 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 115
QE +E++ + RE E Q +E+E R+Q+ + + ++ + Q + E+ Q
Sbjct: 732 RQE---QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 116 QVREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV--REQEGQ 172
+REQ E Q+R +E Q REQ E+E + R ++ + RE+E Q E+E Q+ RE+ Q
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 173 VREQEGQVREQEGQVREQEGQMGEQEGQMGEQE---------------EQMGEQEEQMQK 217
++E+E ++E + + R QE + ++ E+E EQ+ ++++ +Q+
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 218 QEEQMGEQEEQMRKQEEQMGE--QEEQVQKQEEQVQKQEEQMRKQEEQMRE--QEEQMRE 273
+EE++ +E + R+++EQ + +EEQ+Q++EEQ+ ++E + R+++E+ R+ +++++++
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 274 QEEQML---KQKEQTEQEEQTGEQEEQMREQEEQ-MREQEEQMREQE-EQMREQEEQMGK 328
+EEQ+L +K + ++ E+ +EE+++++EEQ +RE+ E+ R QE E+ +++++ +
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
Query: 329 QEEQMW--EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE---QMRKQEEQMR 383
+EEQ+ E++++ +++E+ +++EE++ ++EEQ+ +E + R+++E Q RK+EE +
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088
Query: 384 KQEEQMRKQEE--QMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
++E+ +R++ E + E++ Q E++E +E+E+ + E++E+ R+QE
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Score = 201 bits (511), Expect = 1e-51
Identities = 149/486 (30%), Positives = 291/486 (59%), Gaps = 65/486 (13%)
Query: 7 EELKEKNAELQEELQLV---ETEK--SEIQLH---IKELKRKLETDKIPLPQEGQVR--- 55
+E +E+ AE +E+LQ ETE+ E QL + EL+RK +K +E Q R
Sbjct: 181 QEREERRAE-EEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQ 239
Query: 56 -EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 114
E+E + R++E +R++E +++E+E Q ++ +++E+E Q+R+ E Q +E Q EQ+
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQ---RQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 174
Q +E Q+R ++ + R ++ + R ++ + REQ+ + REQ Q+R ++ + REQ+ + R
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ--QLRREQEERREQQLR-R 353
Query: 175 EQEGQVREQEGQVREQEGQMGEQEGQMGEQ--EEQMGEQEEQMQKQE----------EQM 222
EQE + REQ+ + REQE + EQ+ + +Q EQ +E+Q+++++ EQ
Sbjct: 354 EQEEERREQQLR-REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 223 GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE---QEEQMREQEEQML 279
+E+Q+R++++ EQEE+ +Q+ + +++E+++++++E+ R+ +EE+ E++
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 280 KQKEQTEQEEQTGE-----QEEQMREQ----EEQMREQEEQMREQEEQMREQEEQMGKQE 330
KQ+ + +QEE+ E +EE+ REQ E+Q+R ++E+ REQ + +E+EE++ ++
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Query: 331 EQMWEQKEQMWEQKEQMWKQEEQM---GEQEEQMQKQEEQVR-----KQEEQMRKQE--- 379
+ + + E++EQ+ K+EE+ E+ EQ K+E++ R K+EE+ R+Q
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Query: 380 ------EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ----EEQMGEQKEQMRKQEE 429
EQ K+EE R ++E+ EQ+ + E +E+ R+Q EEQ +++Q+R++++
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 430 HMGEQK 435
EQ+
Sbjct: 653 ERREQR 658
Score = 201 bits (511), Expect = 1e-51
Identities = 128/434 (29%), Positives = 265/434 (61%), Gaps = 37/434 (8%)
Query: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQ 74
+L++E QL++ E+ E+Q +E +R+ E QE Q RE+E +E+E +RE+ +
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQE-------QERQYREEEQLQQEEEQLLREEREK 950
Query: 75 VREQEGQVR-EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 133
R QE + + ++ +++++E Q+ +E + R ++ E+E + RE+E +E+E +RE
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ----EREKKYREEEELQQEEEQLLRE 1006
Query: 134 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQE 191
+ + R QE E Q R+++ +E+E +RE+ + +++E+E Q RE+E +E+E
Sbjct: 1007 EREKRRRQEW-----ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Query: 192 GQMGEQEGQMGEQE-EQMGEQEEQMQKQEEQM--GEQEEQMRKQEEQMGEQEEQVQKQEE 248
+GE+ QE E+ +EE++Q++EEQ+ E E++ R++ E+ +EE++Q++EE
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEE 1121
Query: 249 QVQKQEEQMRKQEEQMRE--QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Q+ ++E + R+++E R+ +EE+++++EEQ+L+++ + + + E E Q RE+EE +
Sbjct: 1122 QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ---ELERQYREEEELQQ 1178
Query: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
E+E+ +RE++E+ R++ E+ ++EE++ QK ++Q ++ E+Q + + Q + ++E
Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQK------RKQRYRDEDQRSDLKWQWEPEKE 1232
Query: 367 QVRKQEEQMRK--QEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQM 424
+ + K + EQ R+ E+ + + + + +GEQ+E+ REQE + +Q+++
Sbjct: 1233 NAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRH 1292
Query: 425 RKQEEHM--GEQKE 436
+EE + EQKE
Sbjct: 1293 FPEEEQLEREEQKE 1306
Score = 199 bits (506), Expect = 4e-51
Identities = 136/485 (28%), Positives = 284/485 (58%), Gaps = 67/485 (13%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E+ + + E ++ELQ +E E+ QL +E ++L+ ++ L ++ + R + Q R+Q+
Sbjct: 818 EQRRRQRREREKELQFLEEEE---QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
Query: 67 QVREQEGQVREQ---------EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 117
+ + +E + R + + Q+R+++ ++E+E +++ +E + R ++ EQE Q
Sbjct: 875 RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ----EQERQY 930
Query: 118 REQEGQVREQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQVREQEGQVR---EQEGQV 173
RE+E +E+E +RE+ + R QE + + ++ +++++E Q+ +E + R E+E +
Sbjct: 931 REEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 174 REQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE 233
RE+E +E+E +RE+ + QE E Q +++E Q++E+ + E+ E+ R QE
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEW-----ERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Query: 234 -EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE--QEEQMREQEEQMLKQ----KEQTE 286
E+ +EE++Q++EEQ+ +E + R+++E R+ +EE+++++EEQ+L++ + + E
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE 1105
Query: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQE--EQMREQEEQMGKQEEQMWEQKEQMWEQK 344
+E Q E+EE +E+E+ +RE+ E+ R QE Q RE+EE ++E+ + E+ E+ Q+
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 345 -EQMWKQEEQMGEQEEQMQKQEEQVRKQEE--QMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
E+ +++EE++ ++EEQ+ ++E++ R+QE Q R++EE R++ +Q + E+Q + K
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 402 QMGEQKE------------------------QMREQEEQ------MGEQKEQMRKQEEHM 431
Q +KE Q+R+++ Q +GEQ+E+ R+QE
Sbjct: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
Query: 432 GEQKE 436
+Q++
Sbjct: 1286 WQQRD 1290
Score = 199 bits (505), Expect = 5e-51
Identities = 140/456 (30%), Positives = 285/456 (62%), Gaps = 40/456 (8%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEG--QVREQEGQ 67
+E++ + +EE QL++ E+ E QLH +E RK L +E Q+R QE + REQE +
Sbjct: 1457 QERHRKFREEEQLLQ-EREEQQLHRQERDRKF------LEEEQQLRRQERDRKFREQELR 1509
Query: 68 VREQEGQVREQEGQVREQEGQVR--EQEGQVREQE-GQVREQEGQVREQEGQVREQEGQV 124
+E E + E+E Q+ Q+ Q + ++E Q+R QE GQ R Q+ + +E + QE +
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQVREQEGQVR 181
++ Q R+++ ++ EQ+ + +EQE + E E Q+R QEGQ + E++ + RE E ++
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 182 EQEGQV---REQEGQMGEQEGQMG--EQEEQMGEQEEQMQKQEEQMGEQ--EEQMRKQEE 234
E+E Q +E++ + E+E Q+ E+E+Q+ ++ ++EEQ+ ++ E+Q+R+QE
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 235 --QMGEQEEQVQKQEEQVQ--KQEEQMRKQE--EQMREQEEQMREQEEQMLKQKEQ---- 284
+ E+E+Q+++QE + + ++E+Q+R+QE + RE+E+ +E E++ L+++E+
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 285 TEQEEQTGEQEEQMREQEEQMRE--QEEQMREQ--EEQMREQE-EQMGKQEEQMWEQKEQ 339
E+E+ E+EEQ ++E+ R+ +EEQ+R++ E+Q+R QE ++ ++EEQ+ +++E+
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Query: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ 399
+ + Q + + E++ Q+++QE+++R++ ++ + EEQ QE+ R+++E E+
Sbjct: 1810 Q-QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868
Query: 400 KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
+++ +++E+ +E +QKE+ R ++ +GE K
Sbjct: 1869 EQKRRQERERKLREEHIRRQQKEEQRHRQ--VGEIK 1902
Score = 197 bits (501), Expect = 2e-50
Identities = 141/454 (31%), Positives = 273/454 (60%), Gaps = 34/454 (7%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
+E+ Q++L+ + E+ E +L +E + +LE ++ E + REQE EQE Q R
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLE-QRLKREHEEERREQELAEEEQE-QAR 694
Query: 70 EQ-EGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQV----REQEGQVREQEG 122
E+ + ++ + + Q+ E E R+ + + R+QEGQ R QE + RE E Q +E+E
Sbjct: 695 ERIKSRIPKWQWQL-ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753
Query: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVR 181
R+Q+ + + ++ + Q + E+ Q +REQ E Q+R +E Q REQ
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
Query: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ-EEQMGEQE 240
E+E + R ++ + E+E Q E+EEQ+ +E Q QEE+ G QE+Q R++ +EQ +Q+
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Query: 241 EQVQKQEEQVQKQEEQMRKQ--EEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
+ Q +EE+ +++ K +EQ+R++++ ++E+EE++ Q+E+ E+ + EQE Q
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL--QREEREKRRRQ-EQERQY 930
Query: 299 REQEEQMREQEEQ-MREQEEQMREQEEQMGKQEEQMWEQKEQMW----------EQKEQM 347
RE EEQ++++EEQ +RE+ E+ R QE + ++++ +QKE+ +++E+
Sbjct: 931 RE-EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Query: 348 WKQEEQMGEQEEQMQKQEEQVRKQEE---QMRKQEEQMRKQEEQMRKQEE--QMGEQKEQ 402
+++EE++ ++EEQ+ ++E + R+++E Q RK++E +++E+ +R++ E ++ E++ Q
Sbjct: 990 YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
Query: 403 MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
E++E +E+E+ +GE++E R+QE +KE
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Score = 196 bits (499), Expect = 3e-50
Identities = 140/461 (30%), Positives = 273/461 (59%), Gaps = 44/461 (9%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKI-PLPQEGQVREQEGQVREQEGQV 68
++K E + EL E E+SE Q +++ R+ +++ QE Q RE+ EQ
Sbjct: 138 RQKRQEQERELAEGE-EQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSC 196
Query: 69 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV--REQEGQVREQEGQVRE 126
+ E + E Q+R +E ++G+ +Q+ Q RE++ +V E+E + R++E +R+
Sbjct: 197 KGHETEEFPDEEQLRRRELLELRRKGREEKQQ-QRRERQDRVFQEEEEKEWRKRETVLRK 255
Query: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-EQEG 185
+E +++E+E Q ++ +++E+E Q+R+ E Q +E Q EQ+ Q +E Q+R +QE
Sbjct: 256 EEEKLQEEEPQ---RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQ--EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
+ REQ+ + EQ+ + +QEE+ +Q EQ +++E+Q+ ++E+ R++++ EQEE+
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE- 371
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQE---EQMLKQKEQTEQEEQTGEQEEQMRE 300
+ EQ ++E+Q+R+ E+Q+R +++ REQ+ EQ L++++Q +E+Q +++ RE
Sbjct: 372 --RREQQLRREQQLRR-EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 301 QEEQMREQEEQM--------REQEEQ----MREQEEQMGKQEEQMWEQKEQMWEQKEQMW 348
QEE+ EQ+ + REQEE+ RE+E + +QE + + K E++ + W
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 349 --KQEEQMGEQEEQMQKQ--EEQVRKQEEQMRKQEEQMRKQ-----EEQMRKQEEQMGEQ 399
+EE+ EQ+E+ ++Q EQ ++E+++++QEE+ R Q E+Q+R+++E+ EQ
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 400 KEQMGEQKEQMREQEEQ-----MGEQKEQMRKQEEHMGEQK 435
+ E+K +E+ EQ E+++Q+ K+EE +Q+
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Score = 196 bits (497), Expect = 5e-50
Identities = 156/497 (31%), Positives = 295/497 (59%), Gaps = 71/497 (14%)
Query: 4 ITNEELKEKNAELQEELQLVETE----KSEIQLHIKELKRKLETDKIPLPQEGQVREQEG 59
+ ++E K E ++ L+ E E K E QL +E +++L D+ + + RE+E
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR-----DRKFREEEQ 1421
Query: 60 QVREQEG--QVREQEGQVREQEGQVR--EQEGQVR-EQEGQVREQEGQVREQEGQV---R 111
Q+ QE + RE+E QVR QE + + E+E Q+R E+ + RE+E ++E+E Q +
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Query: 112 EQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVR--EQEGQVR 167
E++ + E+E Q+R QE + REQE + +E E + E+E Q+ Q+ Q + ++E Q+R
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLR 1541
Query: 168 EQE-GQVREQ--------EGQVREQEG------QVREQEGQMGEQEGQMGEQEEQMGEQE 212
QE GQ R Q E Q+R++ Q R+++ ++ EQ+ + EQE + E E
Sbjct: 1542 RQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE 1601
Query: 213 EQMQKQEEQMG---EQEEQMRKQEEQMGEQEEQVQKQEEQVQK---QEEQMRKQE--EQM 264
+Q+++QE Q E++ + R+ E+ + E+EEQ ++E+ +K +E Q+R+QE +Q+
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Query: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR--EQEEQMREQ 322
R ++ +EEQ+L++ E EQ+ + E++ + RE+E+Q+R QE + + ++E+Q+R Q
Sbjct: 1662 RHDRDRKFREEEQLLQEGE--EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Query: 323 E-EQMGKQEEQMWEQKEQMWEQKEQMWK---QEEQMG-EQEEQMQKQEEQVRK--QEEQM 375
E E+ ++EEQ+ ++ EQ ++++ ++ +EEQ+ E+EEQ +++E+ RK +EEQ+
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL 1779
Query: 376 R--KQEEQMRKQE--------EQMRKQEE------QMGEQKEQMGEQKEQMREQEEQMGE 419
R ++E+Q+R QE EQ+R++ E Q + K + E++ Q+ EQE+++ +
Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839
Query: 420 QKEQMRKQEEHMGEQKE 436
++++ + EE Q++
Sbjct: 1840 ERDRQYRAEEQFATQEK 1856
Score = 191 bits (484), Expect = 1e-48
Identities = 155/525 (29%), Positives = 297/525 (56%), Gaps = 91/525 (17%)
Query: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKL--------ETDKIPL---P 49
+ R +E K ++ + QEE QL+ E+ E + +E RK E ++ PL
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRR-QETDRKFREEEQLLQEREEQPLRRQE 1357
Query: 50 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVR----EQEGQVREQEGQVRE-QEGQVR 104
++ + RE+E + +EQ + E+E ++R QE + + EQ+ + +E+E Q+R+ ++ + R
Sbjct: 1358 RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 105 EQEGQVREQEG--QVREQEGQVREQEGQVR--EQEGQVR-EQEGQVREQEGQVREQEGQV 159
E+E Q+ QE + RE+E QVR QE + + E+E Q+R E+ + RE+E ++E+E Q
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Query: 160 ---REQEGQVREQEGQVREQE--GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ 214
+E++ + E+E Q+R QE + REQE + +E E + E+E Q+ Q+ Q +E+
Sbjct: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE 1537
Query: 215 MQKQEEQMGEQ-----------EEQMRKQEEQ-------------MGEQEEQVQKQEEQV 250
Q + ++ G+Q EEQ+R++ E+ + EQ+ + Q+QE +
Sbjct: 1538 QQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKF 1597
Query: 251 QKQEEQMRKQEEQ----------MREQEEQMREQEEQMLKQKEQ----TEQEEQTGEQEE 296
+ E+Q+R+QE Q RE E+ ++E+EEQ L ++E+ E+E Q QE
Sbjct: 1598 MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER 1657
Query: 297 Q----------MREQEEQMREQEEQM---REQEEQMREQEEQMGKQEEQ---MWEQKEQM 340
+ RE+E+ ++E EEQ +E++ + RE+E+Q+ +QE + + E+++
Sbjct: 1658 EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717
Query: 341 WEQKEQMWKQEEQMGEQEEQMQ-KQEEQVRK--QEEQMR--KQEEQMRKQEEQMR-KQEE 394
++ E+ +++EEQ+ ++ EQ Q +++E+ RK +EEQ+R ++E+Q+R+QE + ++EE
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE 1777
Query: 395 QMGEQKEQM----GEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
Q+ +++E+ E + RE+E+ E++EQ + ++ G+ +
Sbjct: 1778 QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822
Score = 189 bits (481), Expect = 3e-48
Identities = 136/428 (31%), Positives = 258/428 (60%), Gaps = 43/428 (10%)
Query: 17 QEELQLVETEKS----EIQLHIKELKRKLETDKIPLPQEGQVREQE-GQVREQEGQVREQ 71
++EL+ E E+ E QLH ++ +RK L +E Q+R QE GQ R Q+ + +
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKF------LQEEQQLRRQERGQQRRQDRDRKFR 1558
Query: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV---REQE 128
E + QE + ++ Q R+++ ++ EQ+ + +EQE + E E Q+R QEGQ +E++
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 129 GQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
+ RE E ++E+E Q +E++ + E+E Q+R QE REQ+ + +++ + RE+E
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE---REQQLR-HDRDRKFREEEQ 1674
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG--EQEEQMRKQE-EQMGEQEEQ 242
++E E EQ+ + E++ + E+E+Q+++QE + ++E+Q+R+QE E+ +EEQ
Sbjct: 1675 LLQEGE----EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 243 VQKQEEQVQ-KQEEQMRK--QEEQMR-EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
++++ EQ Q +++E+ RK +EEQ+R E+EEQ ++E+ K +E+ + ++ EQ+ +
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
Query: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358
+E + + RE+E+ +E+EEQ +++ GK WE+++ E++EQ +QE +
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYR---WEEEQLQLEEQEQRLRQERDRQYRA 1847
Query: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418
E+ +E+ R++E+++ ++EEQ R+QE + + +EE + Q QKE+ R + Q+G
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ------QKEEQRHR--QVG 1899
Query: 419 EQKEQMRK 426
E K Q K
Sbjct: 1900 EIKSQEGK 1907
Score = 189 bits (480), Expect = 4e-48
Identities = 135/450 (30%), Positives = 273/450 (60%), Gaps = 44/450 (9%)
Query: 7 EELKEKNAELQEEL-QLVETEKSEIQLHIKE-------------LKRKLETDKIPLPQEG 52
EE ++ ELQEE QL + E+ E++ +E L+RK E ++ +E
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE- 320
Query: 53 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 112
R ++ + REQ+ + REQ Q+R ++ + REQ+ + REQE + REQ+ + REQE + RE
Sbjct: 321 --RREQQERREQQEERREQ--QLRREQEERREQQLR-REQEEERREQQLR-REQEEERRE 374
Query: 113 QEGQVREQEGQVREQEGQVREQ---EGQVREQEGQVREQ----EGQVREQEGQVREQEGQ 165
Q Q+R ++ REQ+ + +Q E Q+R ++ REQ E Q+R ++ REQE +
Sbjct: 375 Q--QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
EQ+ + +E +++ ++ + R+ + E E E+ +Q +++++ +++E + +
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE 492
Query: 226 EEQMRKQEEQMGEQ--EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE---EQMLK 280
EE+ R+Q+E+ +Q EQ +++E+++++QEE+ R Q +++R +++ REQE EQ+LK
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQ-QRLRSEQQLRREQEERREQLLK 551
Query: 281 QKEQTEQEEQTGEQEEQMREQEEQMREQ---EEQMREQEEQMREQEEQMGKQEEQMWEQK 337
++E+ E++ +E++++ ++E+ R+Q E+ R Q+ REQEE++ ++ ++ ++
Sbjct: 552 REEEKRLEQE--RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 338 EQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG 397
+ E++EQ K+EE E+ +Q+ K EEQ ++++Q+R+++++ R EQ K+EE+
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR---EQRLKREEEEE 666
Query: 398 EQKEQMGEQKEQMREQEEQMGEQKEQMRKQ 427
++++ + E+ R ++E E++EQ R++
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARER 696
Score = 189 bits (479), Expect = 6e-48
Identities = 127/407 (31%), Positives = 247/407 (60%), Gaps = 32/407 (7%)
Query: 34 IKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 93
+ E KR K L Q+ + E + + ++ Q+ E+ GQ R Q+ Q EQE ++ E E
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ--EQERELAEGE 152
Query: 94 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 153
Q +QE ++ +++ Q R++E + QE Q RE+ EQ + E + E Q+R
Sbjct: 153 EQSEKQE-RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
+E ++G+ +Q+ Q RE++ +V ++E +E + ++E + ++EE++ E+E
Sbjct: 212 RRELLELRRKGREEKQQ-QRRERQDRVFQEE-----EEKEWRKRETVLRKEEEKLQEEEP 265
Query: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR-KQEEQMREQEEQMR 272
Q Q++ + E+EEQ+RK E Q +E Q ++Q++Q ++E+Q+R KQEE+ REQ+E+ R
Sbjct: 266 QRQRE---LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE---EQMGKQ 329
EQ+E+ +Q+E+ EQ+ + REQEE R +++ REQEE+ REQ+ EQ ++
Sbjct: 323 EQQERREQQEERREQQLR--------REQEE--RREQQLRREQEEERREQQLRREQEEER 372
Query: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQM 389
EQ +++Q+ ++EQ ++E+Q+ + EQ ++E+Q+R+ EQ ++E+Q+R++++
Sbjct: 373 REQQLRREQQL--RREQQLRREQQL--RREQQLRREQQLRR--EQQLRREQQLRREQQLR 426
Query: 390 RKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
R+QEE+ EQK + ++++++ ++E+ + ++ + E H E+++
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Score = 188 bits (478), Expect = 7e-48
Identities = 146/486 (30%), Positives = 280/486 (57%), Gaps = 68/486 (13%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEG------------QVREQ 57
+E + + +EE QL++ E+ E L +E RK +++ ++G Q RE+
Sbjct: 1332 QETDRKFREEEQLLQ-EREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERER 1390
Query: 58 EGQVREQEGQVREQEGQVRE-QEGQVREQEGQVREQEG--QVREQEGQVREQEGQVR--E 112
+ EQ+ + +E+E Q+R+ ++ + RE+E Q+ QE + RE+E QVR QE + + E
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450
Query: 113 QEGQVR-EQEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEG--QVREQEGQV 166
+E Q+R E+ + RE+E ++E+E Q +E++ + E+E Q+R QE + REQE +
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 167 REQEGQVREQEGQVREQEGQVR--EQEGQMGEQE-GQMGEQEEQMGEQEEQMQKQEEQMG 223
+E E + E+E Q+ Q+ Q + ++E Q+ QE GQ Q+ +EE+ +QE +
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Query: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM----------REQEEQMRE 273
+ Q R ++ ++ EQ+ + Q+QE + + E+Q+R+QE Q RE E+ ++E
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630
Query: 274 QEEQMLKQKEQT----EQEEQTGEQEEQM----------REQEEQMREQEEQM---REQE 316
+EEQ L ++E+ E+E Q QE + RE+E+ ++E EEQ +E++
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Query: 317 EQMREQEEQMGKQEEQ---MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373
+ RE+E+Q+ +QE + + E+++ ++ E+ +++EEQ+ ++ EQ EQ+R+QE
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ-----EQLRRQER 1745
Query: 374 QMR-KQEEQMR--KQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
+ +EEQ+R ++E+Q+R+QE ++K + EQ Q RE+++ ++ ++ ++EE
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQER---DRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
Query: 431 MGEQKE 436
+ +++E
Sbjct: 1803 LRQERE 1808
Score = 187 bits (474), Expect = 2e-47
Identities = 130/460 (28%), Positives = 273/460 (59%), Gaps = 44/460 (9%)
Query: 9 LKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQV 68
L+E+ + +EE +L + E+ ++ +E +R+ E ++ +E +E+E +RE+ +
Sbjct: 1043 LQERERQYREEEEL-QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 69 R--EQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQV 124
R E+E Q RE+E +E+E +RE+ + R QE Q RE+E +E+E +RE+ +
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 125 REQE--GQVREQEGQVREQEGQVRE-QEGQVREQEGQVREQEG---QVREQEGQVREQEG 178
R QE Q RE+E +E+E +RE QE + +E+E Q RE+E Q R+Q + +Q
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Query: 179 QVR-----EQEGQVREQEGQM-GEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ 232
++ E+E VR+ + G + Q + E+ + Q + +GEQ+E+ R+Q
Sbjct: 1222 DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ 1281
Query: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-----EQ 287
E + +Q ++ +EEQ++++E++ K+ ++ ++E+Q+ +E + +++++T E+
Sbjct: 1282 ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE 1341
Query: 288 EEQTGEQEEQ-MREQEEQMREQEEQMREQEE-----------QMREQEEQMGKQEEQM-- 333
E+ E+EEQ +R QE + +EE++R QE+ + +E+E + K+E+Q+
Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
Query: 334 WEQKEQMWEQKEQMWKQEEQM---GEQEEQMQKQEEQVRKQEEQMR--KQEEQMRKQEEQ 388
E+++Q+ + +++ +++EEQ E++ + +++E+QVR+QE + + ++E+Q+R++ +
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 389 MRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
++EEQ+ +++E EQ+ +E++ + E+++Q+R+QE
Sbjct: 1462 KFREEEQLLQERE---EQQLHRQERDRKFLEEEQQLRRQE 1498
Score = 185 bits (470), Expect = 6e-47
Identities = 122/397 (30%), Positives = 241/397 (60%), Gaps = 37/397 (9%)
Query: 71 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 130
Q+ + E + + ++ Q+ E+ GQ R Q+ Q EQE ++ E E Q +QE ++ +++ Q
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ--EQERELAEGEEQSEKQE-RLEQRDRQ 167
Query: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190
R++E + QE Q RE+ EQ + E + E Q+R +E ++G+ +Q
Sbjct: 168 RRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ 227
Query: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK----- 245
+ + Q+ E+EE+ + E + ++EE+ ++EE R++E Q E+EEQ++K
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ--EEEEQLRKLERQE 285
Query: 246 -----QEEQVQKQ----EEQM-RKQEEQMREQEEQMREQEEQMLKQKEQTEQE---EQTG 292
QEE+ Q+Q E+Q+ RKQEE+ REQ+E+ REQ+E+ +Q+E+ EQ+ EQ
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQE---EQMGKQEEQMWEQKEQMWEQ---KEQ 346
+E+Q+R ++E+ R +++ REQEE+ REQ+ EQ ++E+Q+ +++ EQ +EQ
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 347 MWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE--QKEQMG 404
++E+Q+ +E+Q++++++ R+QEE+ +Q+ + ++E+++++++E+ + ++E+
Sbjct: 406 QLRREQQL-RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 405 EQKEQMREQEEQMGEQKEQMRK-----QEEHMGEQKE 436
E+ EQ R +++ +Q+E+ R+ +EE EQ+E
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Score = 185 bits (469), Expect = 8e-47
Identities = 135/471 (28%), Positives = 269/471 (57%), Gaps = 50/471 (10%)
Query: 5 TNEELKEKNAELQEELQLVETEKS-EIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63
+ ++L+ + E +E+L E EK E + + LKR+ E + L + + R Q+ RE
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 64 QEGQVREQ---EGQVREQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVREQEGQ 116
QE ++ ++ E R ++ + REQ + E E + R+Q E Q ++ Q+R ++ +
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 117 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVRE 175
REQ +++ +E + R ++ RE E + REQE EQE Q RE+ + ++ + + Q+ E
Sbjct: 654 RREQ--RLKREEEEERLEQRLKREHEEERREQELAEEEQE-QARERIKSRIPKWQWQL-E 709
Query: 176 QEGQVREQE--GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG---EQEEQMR 230
E R+ + + R+QEGQ Q EQEE+ +E ++Q QEE+ +QEE+ R
Sbjct: 710 SEADARQSKVYSRPRKQEGQRRRQ-----EQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Query: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQ--------EEQMLKQK 282
+ + EE+ ++ +++ + ++E Q+R +E Q REQ +EQ +Q+
Sbjct: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
Query: 283 EQTEQEEQTGEQEEQM--REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
+ E+E Q E+EEQ+ RE+ +Q++E+E+ ++E +E+ R QE++ + ++ W+ +E+
Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR--RDQKWRWQLEEER 882
Query: 341 WEQK----------EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR--KQEEQMRKQEEQ 388
++ EQ+ K+++ + E+EE++Q++E + R+++EQ R ++EEQ++++EEQ
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 389 MRKQEEQ---MGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+ ++E + E++ Q + K+ +++E+ +GE+ E+ R+QE ++E
Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Score = 184 bits (466), Expect = 2e-46
Identities = 139/503 (27%), Positives = 290/503 (57%), Gaps = 76/503 (15%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
+E+ ++EL+ ++ E+Q ++L R+ + +E Q RE+E +E+E +R
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 70 EQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVR 125
E+ + R QE Q RE+E +E+E +RE+ + R QE Q RE+E +E+E +R
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 126 E-QEGQVREQEGQVREQEGQVR----------------------EQEGQVREQE----GQ 158
E QE + +E+E Q RE+E R E+E VR+ + G+
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245
Query: 159 VREQ-----EGQVREQEGQ------VREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ 207
EQ + Q+R+++ Q + EQ+ + REQE + +Q + +E Q+ +E++
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 208 MGEQEEQMQKQEEQM--GEQEEQMRKQE--EQMGEQEEQVQKQEEQVQKQEEQMRK-QEE 262
++ ++ ++E+Q+ E+EE+ R+QE + E+E+ +Q++EEQ +++E+ RK +EE
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 263 QMREQEEQMR-EQEEQMLKQKE------QTEQEEQTGEQEEQMR-EQEEQMREQEEQM-- 312
++R QE+ + +EEQ L+++E + EQ+ + E+E+Q+R +++ + RE+E+Q+
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 313 REQEEQMREQEEQMGKQEEQ--MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ-------- 362
+E++ + RE+E+Q+ +QE + E+++Q+ +++ + +++EEQ+ ++ E+ Q
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 363 ---KQEEQVRKQEEQMRKQEEQMRKQEEQMR--KQEEQMGEQKEQMGEQKEQMREQEEQM 417
++E+Q+R+QE + +E+++R QE + + ++E+Q+ Q+ Q +E+ + + ++
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 418 GEQKEQMR----KQEEHMGEQKE 436
G+Q+ Q R ++EE + +++E
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQERE 1568
Score = 182 bits (463), Expect = 4e-46
Identities = 138/496 (27%), Positives = 284/496 (57%), Gaps = 73/496 (14%)
Query: 9 LKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIP--LPQEGQVREQEGQVREQEG 66
LK + Q+ L+ + E+ E +L +E++R + ++ L +E E+ Q+ + E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQV-----REQEGQVREQEGQVREQEGQVREQ- 120
Q ++ Q+R ++ + REQ + E+E ++ RE E + REQE EQE Q RE+
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE-QARERI 697
Query: 121 EGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178
+ ++ + + Q+ E E R+ + + R+QEGQ R QE +E++ + RE E Q +E+E
Sbjct: 698 KSRIPKWQWQL-ESEADARQSKVYSRPRKQEGQRRRQE---QEEKRRRRESELQWQEEER 753
Query: 179 QVREQEGQVR----------EQEGQMGEQE----GQMGEQEEQMGEQEEQMQKQEEQMGE 224
R+Q+ + + E++ + G Q + EQ E+ EE+ Q+++ + E
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
Query: 225 QEE-QMRKQEEQMGEQEEQVQKQEEQVQKQE--EQMRKQEEQMREQEEQMREQEEQM-LK 280
+EE + R+++ + E+E Q ++EEQ+Q++E +Q++++E+ ++E +E+ R QE++ K
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Query: 281 QKEQTEQE---------------EQTGEQEEQMREQEEQMREQEEQMREQEEQMRE--QE 323
+ Q E+E EQ ++++ ++E+EE+++ +E + R ++EQ R+ +E
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
Query: 324 EQMGKQEEQM----------WEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ--------E 365
EQ+ ++EEQ+ E++ Q + K+ K+E+ +GE+ E+ ++Q E
Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Query: 366 EQVRKQEEQMRKQEEQMRKQEE---QMRKQEEQMGEQKEQMGEQKEQMR--EQEEQMGEQ 420
E+++++EEQ+ ++E + R+++E Q RK++E E+++ + E++E+ R E+E Q E+
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 421 KEQMRKQEEHMGEQKE 436
+E +++E+ +GE++E
Sbjct: 1054 EELQQEEEQLLGEERE 1069
Score = 181 bits (459), Expect = 1e-45
Identities = 134/461 (29%), Positives = 274/461 (59%), Gaps = 41/461 (8%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKE---LKRKLETDKIPLPQEGQVREQEGQVRE 63
+ LK + E +++L E E+ + +L ++ L+++L+ +++ ++ + REQ + E
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 64 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 123
E + R+Q + EQE ++ Q+R ++ + REQ +++ +E + R ++ RE E +
Sbjct: 625 PEEERRQQLLKSEEQE---ERRQQQLRREQQERREQ--RLKREEEEERLEQRLKREHEEE 679
Query: 124 VREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQV 180
REQE EQE Q RE+ + ++ + + Q+ E E R+ + + R+QEGQ R QE
Sbjct: 680 RREQELAEEEQE-QARERIKSRIPKWQWQL-ESEADARQSKVYSRPRKQEGQRRRQE--- 734
Query: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQ-------MRKQE 233
+E++ + RE E Q E+E +Q+E+ ++ Q Q E+ E+ Q +R+Q
Sbjct: 735 QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
Query: 234 EQMGEQEEQVQKQEEQVQKQEE-QMRKQEEQMREQEEQMREQEEQMLK-QKEQTEQEEQT 291
E+ EE+ Q+++ + ++EE + R+++ + RE+E Q E+EEQ+ + ++ Q QEE+
Sbjct: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
Query: 292 GEQEEQMREQ-EEQMREQEEQMREQEEQMREQ---------EEQMGKQEEQMWEQKEQMW 341
G QE+Q R + +EQ R+Q+ + + +EE+ R + +EQ+ K+++ + E++E++
Sbjct: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
Query: 342 -EQKEQMWKQE-EQMGEQEEQMQKQEEQVRKQEEQMRKQEE---QMRKQEEQMRKQEEQM 396
E++E+ +QE E+ +EEQ+Q++EEQ+ ++E + R+++E Q RK ++ +K+E+ +
Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
Query: 397 GEQKEQMGEQ-KEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
GE+ E+ Q +E+ +EE++ +++EQ+ ++E ++E
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Score = 181 bits (459), Expect = 1e-45
Identities = 133/464 (28%), Positives = 282/464 (60%), Gaps = 55/464 (11%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQV-REQEGQVREQE 65
E+ + ++ + Q++LQ + E+ E +E +R + D+ P+E Q+ RE++ + + ++
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDRE-QERRRWQQRDR-HFPEEEQLEREEQKEAKRRD 1311
Query: 66 GQVREQEGQVREQEGQVR---EQEGQVREQEGQVREQEGQV---REQEGQVREQEGQVRE 119
+ +E++ +RE+ + R E + + RE+E ++E+E Q +E++ + RE+E + +E
Sbjct: 1312 RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE 1371
Query: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-QEGQVREQEGQVREQEG 178
Q + E+E ++R QE RE++ EQ+ + +E+E Q+R+ ++ + RE+E Q+ QE
Sbjct: 1372 QGRKFLEEEQRLRRQE---RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
Query: 179 --QVREQEGQVREQEGQMG--EQEGQM--------GEQEEQMGEQEEQM---QKQEEQMG 223
+ RE+E QVR QE + E+E Q+ E+E+ + E+EEQ Q+++ +
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL 1488
Query: 224 EQEEQMRKQEEQMGEQEEQVQKQ---------EEQVQKQEEQMR--KQEEQMREQE--EQ 270
E+E+Q+R+QE +E++++ Q E+Q+ +Q+ Q + ++E+Q+R QE +Q
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Query: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330
R+ ++ +++EQ QE + + Q R+++ ++ EQ+ + +EQE + E E+Q+ +QE
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Query: 331 EQMWEQKEQMWEQKEQMWKQEEQ-MGEQEEQMQKQEEQVRK---QEEQMRKQ--EEQMRK 384
Q +Q+ +++++ ++++EQ + E+EEQ ++E+ RK +E Q+R+Q E+Q+R
Sbjct: 1609 GQ-----QQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
Query: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
++ ++EEQ+ ++ E EQ+ + +E++ + E+++Q+R+QE
Sbjct: 1664 DRDRKFREEEQLLQEGE---EQQLRRQERDRKFREEEQQLRRQE 1704
Score = 177 bits (448), Expect = 2e-44
Identities = 132/496 (26%), Positives = 280/496 (56%), Gaps = 75/496 (15%)
Query: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
R E K+ +LQ++ + + E+ E + + K+ E +++ +E +RE+ + R
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 63 EQEG--QVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVR 118
QE Q R+++ +E+E +RE+ + +++E+E Q RE+E +++++E Q+ +E + R
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE-ELQQEEEQLLGEERETR 1071
Query: 119 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR--EQEGQVREQEGQVREQEGQVREQ 176
++ E E Q R++E +E+E +RE+ + R E+E Q RE+E +E+E +RE+
Sbjct: 1072 RRQ----ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Query: 177 EGQVREQE--GQVREQEGQMGEQEGQMGEQEEQMGEQE-EQMQKQEEQMGEQEEQMRKQE 233
+ R QE Q RE+E E+E + E+ E+ QE E+ ++EE++ ++EEQ+ ++E
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 234 EQMGEQEEQVQ-KQEEQVQKQEEQMRKQEEQMRE------------------------QE 268
++ QE + Q ++EE++Q+Q+ + R ++E R +
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN 1247
Query: 269 EQMREQEEQMLKQKE-QTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM-REQEEQM 326
EQ R+ E+ L+ ++ Q + + GEQ+E+ REQE + +Q ++ +EEQ+ RE++++
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307
Query: 327 GKQEEQMWEQKEQMWEQKEQMWKQEE---QMGEQEEQMQKQEEQ-VRKQEEQMRKQEEQM 382
+++ + E+K+ + E++E+ +++E + E+E+ +Q++EEQ +R+QE + +EE++
Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL 1367
Query: 383 R-------------------------KQEEQMR--KQEEQMGEQKEQMGEQKEQM---RE 412
R K+E+Q+R ++E+Q+ + +++ ++EQ +E
Sbjct: 1368 RHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE 1427
Query: 413 QEEQMGEQKEQMRKQE 428
++ + E+++Q+R+QE
Sbjct: 1428 RDRKFREEEQQVRRQE 1443
Score = 175 bits (443), Expect = 8e-44
Identities = 121/461 (26%), Positives = 268/461 (58%), Gaps = 42/461 (9%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
+E+ ++EL+ E+ E+Q ++L R+ + E Q RE+E +E+E +R
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 70 E-QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-EQEGQVREQE----GQ 123
E QE + +E+E Q RE+E R++ Q E Q + + Q E+E VR+ + G+
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245
Query: 124 VREQ-----EGQVREQEGQ------VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 172
EQ + Q+R+++ Q + EQ+ + REQE + +Q + +E Q+ +E +
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 173 VREQEGQVREQEGQV----REQEGQMGEQEGQMGEQEEQMGEQEEQ-MQKQEEQMGEQEE 227
++ + ++E Q+ RE++ + E + + E+E+ + E+EEQ +++QE +EE
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 228 QMRKQEE--QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR--EQEEQMREQEEQMLKQKE 283
++R QE+ + E+E+++++QE +E + K+E+Q+R E+E+Q+R+ ++ +++E
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQE-----RERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 284 QTEQEEQTGEQEEQMREQEEQMREQEEQMR--EQEEQMREQEEQMGKQEEQMWEQKEQM- 340
Q + E++ + RE+E+Q+R QE + + E+E+Q+R++ + ++EEQ+ +++E+
Sbjct: 1421 QQLSRQ---ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Query: 341 ---WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR--KQEEQMRKQEEQMRKQEEQ 395
E+ + ++E+Q+ QE + +E+++R QE + + ++E+Q+ +Q+ Q + +E+
Sbjct: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE 1537
Query: 396 MGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
++++ G+Q+ Q R+++ + EQ Q R++++ ++++
Sbjct: 1538 QQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
Score = 173 bits (438), Expect = 3e-43
Identities = 135/512 (26%), Positives = 278/512 (54%), Gaps = 84/512 (16%)
Query: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
R EE +E+ +++L+ + + E QL ++ R+ + L +E Q+R ++ R
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ----LRREQQLRREQQLRR 421
Query: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQ----VREQEGQVREQEGQV----REQE 114
EQ+ + ++E + ++ Q R ++ REQE + RE+E + EQE + R+QE
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 115 GQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQ---EGQVREQ 169
+ RE+ ++ E+E + +++ E Q+R ++ + REQ + +E+E +++++ E Q+R +
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 170 EGQVREQ-----EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ----------EEQ 214
+ + REQ E + EQE + + + + E+ Q+ ++EE+ +Q E++
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 215 MQKQEEQMGEQEE---QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271
++++E + EQEE Q K+EE E+ +Q+ K EEQ +++++Q+R+++++ REQ +
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 272 REQEE---QMLKQKEQTEQEEQTGEQEEQ------------------------------- 297
E+EE Q LK++ + E+ EQ +EEQ
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 298 -MREQEEQMR--EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ---MWEQKEQMWKQE 351
R+QE Q R EQEE+ R +E +++ QEE+ +++Q EQ+ W+ +E+ +
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQ-------EEQMRKQEEQMRKQEEQMGEQKEQM- 403
+++ + +++E Q+R +E Q R+Q E++ R+++ + R++E Q E++EQ+
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 404 -GEQKEQMREQEEQMGEQKEQMRKQEEHMGEQ 434
E+ +Q++E+E+ + E +E+ R QE+ ++
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Score = 173 bits (438), Expect = 3e-43
Identities = 131/464 (28%), Positives = 273/464 (58%), Gaps = 56/464 (12%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEG---QVREQEG 66
+E ++EL+ E+ E+Q ++L R+ E +K +E Q RE+E Q R+Q
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLRE-EQEKRRQERERQYREEEELQRQKRKQRY 1214
Query: 67 QVREQEGQVR-----EQEGQVREQE----GQVREQ-----EGQVREQEGQ------VREQ 106
+ +Q ++ E+E VR+ + G+ EQ + Q+R+++ Q + EQ
Sbjct: 1215 RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ 1274
Query: 107 EGQVREQEGQVREQEGQVREQEGQV-REQEGQVREQEGQVREQEGQVREQEGQVR---EQ 162
+ + REQE + +Q + +E Q+ RE++ + + ++ + +E++ +RE+ + R E
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 163 EGQVREQEGQVREQEGQV---REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ--K 217
+ + RE+E ++E+E Q +E++ + RE+E + EQ + E+E+++ QE + + K
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK 1394
Query: 218 QEEQMG--EQEEQMRKQEEQMGEQEEQV---QKQEEQVQKQEEQMRKQEEQMR--EQEEQ 270
+E+Q+ E+E+Q+R+ ++ +EEQ Q+++ + +++E+Q+R+QE + + E+E+Q
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE--EQMREQEEQMGK 328
+R++ + +++EQ QE + EQ+ +E++ + E+E+Q+R QE + REQE + +
Sbjct: 1455 LRQERHRKFREEEQLLQERE--EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Query: 329 QEEQMWEQKEQMWEQKEQ--MWKQEEQMGEQEEQMQKQEEQVRK--QEEQMRKQEEQMRK 384
E + E+++Q+ Q+ Q ++E+Q+ QE Q+++++ RK +EEQ+R++ E
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE---- 1568
Query: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
E+Q+ +QE ++K ++ EQK + +EQE + E ++Q+R+QE
Sbjct: 1569 -EQQLSRQER---DRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Score = 172 bits (436), Expect = 5e-43
Identities = 150/479 (31%), Positives = 263/479 (54%), Gaps = 49/479 (10%)
Query: 3 RITNEELKEKNAELQEE-LQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQ---- 57
R +E +E+ E +E+ L+ + E+ E QL +E + + ++ QE + REQ
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLR-REQEEERREQQLRREQEEERREQQLRR 379
Query: 58 EGQVREQEGQVREQ----EGQVREQEGQVREQ----EGQVREQEGQVREQEGQVREQE-G 108
E Q+R ++ REQ E Q+R ++ REQ E Q+R ++ REQE + EQ+
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439
Query: 109 QVREQEGQVREQEGQ----VREQEGQVREQEGQ----VREQEGQVRE-----QEGQVREQ 155
Q R ++ REQE + RE+E + EQE + R+QE + RE +E + REQ
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499
Query: 156 ----EGQVREQEGQVREQEGQVREQEGQVREQ---EGQVREQEGQMGEQEGQMGEQEEQM 208
E Q+R ++ + REQ + +E+E +++++ E Q+R ++ + EQ + +EE+
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ--LLKREEEKR 557
Query: 209 GEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE--EQVQKQEEQMRKQEEQMRE 266
EQE + Q+ + + E+ +Q+ K+EE+ +Q + +++E EQ K+EE R ++E+ RE
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
Query: 267 Q----EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ 322
Q EE E+ +Q+LK +EQ E+ +Q +E+Q R ++ RE+EE+ EQ + RE
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK-REH 676
Query: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQM-GEQEEQMQKQEEQVRKQEEQMRK--QE 379
EE+ +QE EQ++ K ++ K + Q+ E + + K + RKQE Q R+ QE
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736
Query: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQM--REQEEQMGEQKEQMRKQEEHMGEQKE 436
E+ R++E +++ QEE+ +++Q EQ+ + Q E+ E+ Q + EQ+E
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Score = 170 bits (431), Expect = 2e-42
Identities = 123/404 (30%), Positives = 249/404 (61%), Gaps = 54/404 (13%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
++++ + +EE QL + E+ E QL +E RK ++ EQ+ + +EQE +
Sbjct: 1551 QDRDRKFREEEQLRQ-EREEQQLSRQERDRKF-----------RLEEQKVRRQEQERKFM 1598
Query: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
E E Q+R QEGQ + ++ E++ + RE E ++E+E EQ+ +E++ + E+E
Sbjct: 1599 EDEQQLRRQEGQQQLRQ----ERDRKFREDEQLLQERE----EQQLHRQERDRKFLEEEP 1650
Query: 130 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Q+R QE REQ+ + +++ + RE+E ++E E EQ+ + +E++ + RE+E Q+R
Sbjct: 1651 QLRRQE---REQQLR-HDRDRKFREEEQLLQEGE----EQQLRRQERDRKFREEEQQLRR 1702
Query: 190 QEGQMGEQEGQMGEQEEQMGEQEEQMQKQE-EQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
Q E+E + ++E+Q+++QE E+ +EEQ+R++ EQ EQ+++QE
Sbjct: 1703 Q------------ERERKFLQEEQQLRRQELERKFREEEQLRQETEQ-----EQLRRQER 1745
Query: 249 QVQ-KQEEQMR--KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305
+ +EEQ+R ++E+Q+R QE + +EE+ L+Q E+ EQ+ ++ E + + RE+E+
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ-EREEQQLRSQESDRKFREEEQLR 1804
Query: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE 365
+E+EEQ + Q R+ + + +++ Q+ EQ++++ +++++ ++ EEQ QE+ +++E
Sbjct: 1805 QEREEQ--QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS-RREE 1861
Query: 366 EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQ 409
+++ ++EEQ R+QE + + +EE +R+Q+++ ++ Q+GE K Q
Sbjct: 1862 QELWQEEEQKRRQERERKLREEHIRRQQKE-EQRHRQVGEIKSQ 1904
Score = 167 bits (424), Expect = 1e-41
Identities = 125/429 (29%), Positives = 263/429 (61%), Gaps = 38/429 (8%)
Query: 24 ETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 83
E EK K + E ++ ++ Q+R+++ Q ++ + + EQ+ + REQE +
Sbjct: 1228 EPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ-QDLQHLLGEQQERDREQERRRW 1286
Query: 84 EQEGQVREQEGQV-REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 142
+Q + +E Q+ RE++ + + ++ + +E++ +RE+ RE++ + +E + + RE+E
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE----REEKRRRQETDRKFREEE 1342
Query: 143 GQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEG 199
++E+E Q +E++ + RE+E + +EQ + E+E ++R QE RE++ EQ+
Sbjct: 1343 QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQE---RERKFLKEEQQL 1399
Query: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE-EQVQKQEEQMR 258
+ E+E+Q+ + ++ ++EEQ ++E+ RK E+E+QV++QE E+ +EEQ
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRK----FREEEQQVRRQERERKFLEEEQQL 1455
Query: 259 KQE--EQMREQEEQMREQEEQMLKQKE------QTEQEEQTGEQEEQMREQEEQMREQEE 310
+QE + RE+E+ ++E+EEQ L ++E + EQ+ + E++ + REQE + +E E
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
Query: 311 QMREQEEQM-REQEEQMGKQEEQMWEQKE---QMWEQKEQMWKQEEQM-GEQEEQMQKQE 365
+ E+E+Q+ R+Q ++ QEEQ ++E Q + +++ +++EEQ+ E+EEQ ++
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575
Query: 366 EQVRK---QEEQMRKQEEQMR--KQEEQMRKQE--EQMGEQKEQMGEQKEQ-MREQEEQM 417
E+ RK +E+++R+QE++ + + E+Q+R+QE +Q+ +++++ + EQ ++E+EEQ
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 418 GEQKEQMRK 426
++E+ RK
Sbjct: 1636 LHRQERDRK 1644
Score = 163 bits (413), Expect = 2e-40
Identities = 128/481 (26%), Positives = 257/481 (53%), Gaps = 52/481 (10%)
Query: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKE-------LKRKLETDKIP--LPQE 51
+ R EE +E+ +L+EE + + E+ E QL ++ LKR+ E +++ L E
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111
Q+R ++ + REQ + E++ +E+ Q ++E + R + RE+E R Q+ R
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE---RRQQRLKR 592
Query: 112 EQEGQVREQ---EGQVREQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVREQEG 164
EQE ++ ++ E R ++ + REQ + E E + R+Q E Q ++ Q+R ++
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 165 QVREQEGQVREQEGQV-----REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE 219
+ REQ + E+E ++ RE E + REQE + E+E + + + + Q Q +
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQE--LAEEEQEQARERIKSRIPKWQWQLES 710
Query: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
E Q + + +Q G++ Q +QEE+ +++E +++ QEE+ +++Q EQ
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQ--EQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFT 768
Query: 280 KQKEQTEQEEQ-----------TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328
Q + E+ E+ ++E Q+R +E Q REQ E+E++ R ++ + +
Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Query: 329 QEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ-MQKQEEQVRKQEEQMRKQEEQMRKQ-- 385
+E Q E++EQ+ ++ QEE+ G QE+Q ++ +EQ R Q+ + + +EE+ R++
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 386 -------EEQMRKQEEQMGEQKEQMGEQKEQMR---EQEEQMGEQKEQMRKQEEHMGEQK 435
+EQ+RK+++ + E++E++ ++ + R EQE Q E+++ +++E+ + E++
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER 948
Query: 436 E 436
E
Sbjct: 949 E 949
Score = 126 bits (317), Expect = 3e-29
Identities = 74/267 (27%), Positives = 161/267 (60%), Gaps = 30/267 (11%)
Query: 194 MGEQEGQMGEQEEQMGEQEEQMQ--KQEEQMGEQEEQMRKQEEQMGEQEEQV-QKQEEQV 250
+G+ G E+ + +E +Q +QEE E + R+ EE+ G++ Q Q+QE ++
Sbjct: 89 LGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL 148
Query: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE---------- 300
+ EEQ KQE R ++ + ++E++ +Q+++ ++ E+ +EEQ++
Sbjct: 149 AEGEEQSEKQE---RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP 205
Query: 301 QEEQMREQE------EQMREQEEQMREQEEQMGKQEEQM-WEQKEQMWEQKEQMWKQEE- 352
EEQ+R +E + E+++Q RE+++++ ++EE+ W ++E + ++E+ ++EE
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 353 ----QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKE 408
++ E+EEQ++K E Q ++E Q +Q++Q ++E+Q+R+++E+ E++EQ E++E
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE--ERREQQEERRE 323
Query: 409 QMREQEEQMGEQKEQMRKQEEHMGEQK 435
Q +E+Q +++Q+R+++E EQ+
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQ 350
Score = 114 bits (285), Expect = 2e-25
Identities = 85/269 (31%), Positives = 157/269 (58%), Gaps = 18/269 (6%)
Query: 16 LQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEG--QVREQEGQVREQEG 73
L+EE QL E+ + H ++ K + E + +E Q+R QE + RE+E Q+R QE
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 74 QVR--EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ---VREQEGQVREQE 128
+ + ++E Q+R QE E++ + EQ Q EQE Q+R QE + E++ + +E
Sbjct: 1706 ERKFLQEEQQLRRQE---LERKFREEEQLRQETEQE-QLRRQERYRKILEEEQLRPEREE 1761
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
Q+R QE R+++ + EQ Q RE++ Q+R QE + +E + QE + ++ Q R
Sbjct: 1762 QQLRRQE---RDRKFREEEQLRQEREEQ-QLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
+ + + E++ Q+ EQE+++ ++ ++ + EEQ QE+ R++E+++ ++EEQ ++QE
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS-RREEQELWQEEEQKRRQER 1876
Query: 249 QVQKQEEQMRKQ--EEQMREQEEQMREQE 275
+ + +EE +R+Q EEQ Q +++ QE
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 88.2 bits (217), Expect = 1e-17
Identities = 78/259 (30%), Positives = 147/259 (56%), Gaps = 32/259 (12%)
Query: 11 EKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVR---EQEGQVREQEGQ 67
+++ + +EE QL++ E E QL +E RK ++ L ++ + R ++E Q+R QE +
Sbjct: 1664 DRDRKFREEEQLLQ-EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722
Query: 68 VR----EQEGQVREQEGQVREQEGQ---VREQEGQVREQEGQVREQEGQVR-EQEGQVRE 119
+ EQ Q EQE Q+R QE + E++ + +E Q+R QE + +E Q+R+
Sbjct: 1723 RKFREEEQLRQETEQE-QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781
Query: 120 Q--EGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 175
+ E Q+R QE + RE+E +E+E EQ+ + ++++G+ R +E Q+ Q+ E
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQERE----EQQLRPQQRDGKYRWEEEQL-----QLEE 1832
Query: 176 QEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
QE ++R++ + E Q QE + +E+++ ++EEQ ++QE + +EE +R+Q
Sbjct: 1833 QEQRLRQERDRQYRAEEQFATQE-KSRREEQELWQEEEQKRRQERERKLREEHIRRQ--- 1888
Query: 236 MGEQEEQVQKQEEQVQKQE 254
++EEQ +Q +++ QE
Sbjct: 1889 --QKEEQRHRQVGEIKSQE 1905
Score = 69.3 bits (168), Expect = 6e-12
Identities = 50/171 (29%), Positives = 98/171 (57%), Gaps = 7/171 (4%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
+E+ ++ EE QL E+ E QL +E RK ++ Q Q RE++ Q+R QE +
Sbjct: 1743 QERYRKILEEEQL-RPEREEQQLRRQERDRKFREEE----QLRQEREEQ-QLRSQESDRK 1796
Query: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQVREQE 128
+E + QE + ++ Q R+ + + E++ Q+ EQE ++R E++ Q R +E +++
Sbjct: 1797 FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 179
+ EQE E++ + +E+E ++RE+ + +++E Q Q G+++ QEG+
Sbjct: 1857 SRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/103 (24%), Positives = 57/103 (55%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
+E +E+ Q+ E+ ++QL +E + + E D+ +E +++ + EQE
Sbjct: 1805 QEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL 1864
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 109
E++ + +E+E ++RE+ + +++E Q Q G+++ QEG+
Sbjct: 1865 WQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 202 bits (513), Expect = 6e-52
Identities = 107/204 (52%), Positives = 163/204 (79%), Gaps = 7/204 (3%)
Query: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
+EE+M+++E++M E+EE MR+QEE+M EQEE++++QEE++ +QEE+M++QEE+M EQEE+
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330
M EQEE+M +Q+ EQ+E+ EQ+E++RE+EE+MREQ +M +Q E+MRE+++ QE
Sbjct: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK---TQE 117
Query: 331 EQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMR 390
E+M EQ+E+M EQ+E MW+QEE+M EQEE+M +QEE++R+QEE+MR+QEE+M+ QEE+MR
Sbjct: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
Query: 391 KQEEQMGEQKEQMGEQKEQMREQE 414
E GE E G ++ QE
Sbjct: 178 DVEPAGGEAGE--GSPQDNPTAQE 199
Score = 197 bits (502), Expect = 1e-50
Identities = 103/187 (55%), Positives = 151/187 (80%), Gaps = 16/187 (8%)
Query: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311
++EE+MR++E++MRE+EE MREQEE+M EQEE+MREQEE+M EQEE+
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKM-------------QEQEEKMREQEEKMWEQEEK 48
Query: 312 MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE--EQVR 369
M+EQEE+M EQEE+M +QEE+MWEQ +++ EQKE+MW+Q+E++ E+EE+M++Q+ +QV
Sbjct: 49 MQEQEEKMWEQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVE 107
Query: 370 KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
K E+ + QEE+M++QEE+M++QEE M EQ+E+M EQ+E+M EQEE+M EQ+E+MR+QEE
Sbjct: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
Query: 430 HMGEQKE 436
M Q+E
Sbjct: 168 KMQGQEE 174
Score = 194 bits (493), Expect = 1e-49
Identities = 105/198 (53%), Positives = 161/198 (81%), Gaps = 12/198 (6%)
Query: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ 284
+EE+MR++E++M E+EE +++QEE++Q+QEE+MR+QEE+M EQEE+M+EQEE+M
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW----- 57
Query: 285 TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQK 344
EQEE+ EQEE+M EQ+ ++ EQ+E+M EQ+E++RE+EE+M +E++MW+Q E+M E+K
Sbjct: 58 -EQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMREKK 113
Query: 345 EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMG 404
+ QEE+M EQEE+MQ+QEE + +QEE+M++QEE+M +QEE+MR+QEE+M EQ+E+M
Sbjct: 114 K---TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170
Query: 405 EQKEQMREQEEQMGEQKE 422
Q+E+MR+ E GE E
Sbjct: 171 GQEEKMRDVEPAGGEAGE 188
Score = 190 bits (482), Expect = 2e-48
Identities = 98/185 (52%), Positives = 151/185 (81%), Gaps = 9/185 (4%)
Query: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
+E +M E+E++M E+EE M++QEE+M EQEE+MR+QEE+M EQEE++Q+QEE++ +QEE+
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE--EQMREQEEQMRE 314
M +QEE+M EQ +++ EQ+E+M EQ+E+ E+EE+MREQ+ +Q+ + E+ +
Sbjct: 63 MWEQEEKMWEQ-QRLPEQKEKM------WEQDERLREKEERMREQKMWQQVEKMREKKKT 115
Query: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
QEE+M+EQEE+M +QEE MWEQ+E+M EQ+E+MW+QEE+M EQEE+M++QEE+++ QEE+
Sbjct: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
Query: 375 MRKQE 379
MR E
Sbjct: 176 MRDVE 180
Score = 185 bits (469), Expect = 8e-47
Identities = 100/186 (53%), Positives = 153/186 (82%), Gaps = 6/186 (3%)
Query: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
+RE+E +M E+E +M E+EE M EQEE+MQ+QEE+M EQEE+M +QEE+M EQEE++ +Q
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
EE++ +QEE+M +Q +++ EQ+E+M EQ+E+ L++KE+ +E++ +Q E+MRE++ +
Sbjct: 60 EEKMWEQEEKMWEQ-QRLPEQKEKMWEQDER-LREKEERMREQKMWQQVEKMREKK---K 114
Query: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
QEE+M+EQEE+M+EQEE M +QEE+M EQ+E+MWEQ+E+M +QEE+M EQEE+MQ QEE
Sbjct: 115 TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174
Query: 367 QVRKQE 372
++R E
Sbjct: 175 KMRDVE 180
Score = 182 bits (463), Expect = 4e-46
Identities = 102/193 (52%), Positives = 154/193 (79%), Gaps = 13/193 (6%)
Query: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
+RE+E ++RE+E ++RE+E +REQE +M EQE +M EQEE+M EQEE+MQ+QEE+M EQ
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
EE+M +QEE+M EQ +++ +Q+E+M +Q+E++RE+EE+MREQ +M +Q E+
Sbjct: 60 EEKMWEQEEKMWEQ--------QRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKM 109
Query: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345
++++T QEE+M+EQEE+M+EQEE M EQEE+M+EQEE+M +QEE+M EQ+E+M EQ+E
Sbjct: 110 REKKKT--QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
Query: 346 QMWKQEEQMGEQE 358
+M QEE+M + E
Sbjct: 168 KMQGQEEKMRDVE 180
Score = 182 bits (461), Expect = 7e-46
Identities = 101/196 (51%), Positives = 154/196 (78%), Gaps = 10/196 (5%)
Query: 138 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ 197
+RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE +M EQ
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE--EQVQKQEEQVQKQEE 255
E +M EQEE+M EQ +++ +Q+E+M EQ+E++R++EE+M EQ+ +QV+K E+ + QEE
Sbjct: 60 EEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
Query: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
+M++QEE+M+EQEE M EQEE+M EQEE+ EQEE+MREQEE+MREQEE+M+ Q
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKM------QEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
Query: 316 EEQMREQEEQMGKQEE 331
EE+MR+ E G+ E
Sbjct: 173 EEKMRDVEPAGGEAGE 188
Score = 162 bits (410), Expect = 6e-40
Identities = 90/205 (43%), Positives = 152/205 (74%), Gaps = 4/205 (1%)
Query: 110 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 169
+RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE--EQMQKQEEQMGEQEE 227
E ++ EQE ++ EQ+ ++ EQ+ +M EQ+ ++ E+EE+M EQ+ +Q++K E+ QEE
Sbjct: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
Query: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
+M++QEE+M EQEE + +QEE++Q+QEE+M +QEE+MREQEE+MREQEE+M Q+E+
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Query: 288 EEQTGEQEEQMREQEEQMREQEEQM 312
E G + + Q+ ++ Q+
Sbjct: 179 VEPAGGEAGEGSPQDNPTAQEIMQL 203
Score = 159 bits (403), Expect = 4e-39
Identities = 93/207 (44%), Positives = 156/207 (75%), Gaps = 8/207 (3%)
Query: 96 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 155
+RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE----Q 211
E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E +M EQ+ M +Q E+M E Q
Sbjct: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKTQ 116
Query: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271
EE+MQ+QEE+M EQEE M +QEE+M EQEE++ +QEE++++QEE+MR+QEE+M+ QEE+M
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 272 REQEEQMLKQKEQTEQEEQTGEQEEQM 298
R+ E + E + Q+ T ++ Q+
Sbjct: 177 RDVEPAGGEAGEGSPQDNPTAQEIMQL 203
Score = 156 bits (395), Expect = 3e-38
Identities = 94/204 (46%), Positives = 153/204 (75%), Gaps = 9/204 (4%)
Query: 89 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 148
+RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 149 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE----Q 204
E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ M +Q +M E Q
Sbjct: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKTQ 116
Query: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
EE+M EQEE+MQ+QEE M EQEE+M++QEE+M EQEE++++QEE++++QEE+M+ QEE+M
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 265 REQEEQMREQEEQMLKQKEQTEQE 288
R+ E E E Q T QE
Sbjct: 177 RDVEPAGGEAGEGS-PQDNPTAQE 199
Score = 154 bits (389), Expect = 2e-37
Identities = 87/182 (47%), Positives = 141/182 (77%), Gaps = 4/182 (2%)
Query: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134
+RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 135 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEG 192
E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ QV + + + QE
Sbjct: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
Query: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK 252
+M EQE +M EQEE M EQEE+MQ+QEE+M EQEE+MR+QEE+M EQEE++Q QEE+++
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Query: 253 QE 254
E
Sbjct: 179 VE 180
Score = 147 bits (370), Expect = 2e-35
Identities = 83/182 (45%), Positives = 140/182 (76%), Gaps = 4/182 (2%)
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEG 178
E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ QV + + + QE
Sbjct: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
Query: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
+++EQE +++EQE M EQE +M EQEE+M EQEE+M++QEE+M EQEE+M+ QEE+M +
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Query: 239 QE 240
E
Sbjct: 179 VE 180
Score = 145 bits (367), Expect = 5e-35
Identities = 85/190 (44%), Positives = 141/190 (74%), Gaps = 4/190 (2%)
Query: 54 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 113
+RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEG 171
E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ QV + + + QE
Sbjct: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
Query: 172 QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK 231
+++EQE +++EQE + EQE +M EQE +M EQEE+M EQEE+M++QEE+M QEE+MR
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Query: 232 QEEQMGEQEE 241
E GE E
Sbjct: 179 VEPAGGEAGE 188
Score = 128 bits (321), Expect = 1e-29
Identities = 78/193 (40%), Positives = 136/193 (70%), Gaps = 13/193 (6%)
Query: 34 IKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 93
++E +R E +K +E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQE
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 94 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 153
++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ ++ +Q ++RE++
Sbjct: 61 EKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKK---- 113
Query: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
+ QE +++EQE +++EQE + EQE +++EQE +M EQE +M EQEE+M EQEE
Sbjct: 114 ------KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
Query: 214 QMQKQEEQMGEQE 226
+MQ QEE+M + E
Sbjct: 168 KMQGQEEKMRDVE 180
Score = 117 bits (293), Expect = 2e-26
Identities = 70/178 (39%), Positives = 125/178 (70%), Gaps = 3/178 (1%)
Query: 38 KRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 97
K+ E +++ QE +++EQE ++REQE ++ EQE +++EQE ++ EQE ++ EQE ++
Sbjct: 12 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71
Query: 98 EQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQ 155
EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ QV + + + QE +++EQE +++EQ
Sbjct: 72 EQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130
Query: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
E + EQE +++EQE ++ EQE ++REQE ++REQE +M QE +M + E GE E
Sbjct: 131 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGE 188
Score = 108 bits (270), Expect = 1e-23
Identities = 67/211 (31%), Positives = 138/211 (65%), Gaps = 14/211 (6%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E ++E+ +++EE +++ ++ ++Q ++++ QE ++ EQE +++EQE
Sbjct: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQEEKMQEQEE 54
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQV 124
++ EQE ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ QV + +
Sbjct: 55 KMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113
Query: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
+ QE +++EQE +++EQE + EQE +++EQE ++ EQE ++REQE ++REQE +++ QE
Sbjct: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173
Query: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQM 215
++R+ E GE G+ Q+ ++ Q+
Sbjct: 174 EKMRDVEPAGGE-AGEGSPQDNPTAQEIMQL 203
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 189 bits (480), Expect = 4e-48
Identities = 108/302 (35%), Positives = 206/302 (68%), Gaps = 12/302 (3%)
Query: 116 QVREQEGQVREQEGQVREQEGQVREQEGQV-----REQEGQVREQEGQVREQEGQVREQE 170
Q++++ +R++ V Q Q + Q+ R QE ++REQE ++REQE ++REQE
Sbjct: 161 QLQDETNHLRKELESVGRQL-QAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219
Query: 171 GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR 230
++ EQE ++REQE ++REQE ++ EQE ++ E EE++ EQEE++ +QEE++ EQEE++
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 279
Query: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
+QEE++ EQEE++++QEE++ +QEE++R+QEE++ EQEE++REQEE++ +Q E+ +E+
Sbjct: 280 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EKLPGQER 338
Query: 291 TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ 350
E+ E++ EQE + +E++E++ E+E + E EE + ++E++ +Q E++W+Q + ++
Sbjct: 339 LLEEVEKLLEQERR-QEEQERLLERERLLEEVEELL--EQERLRQQDERLWQQ--ETLQE 393
Query: 351 EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQM 410
E++ E E ++ E + +Q + R E++ + + + E+Q+ E K+ G ++ +
Sbjct: 394 LERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRG 453
Query: 411 RE 412
E
Sbjct: 454 SE 455
Score = 187 bits (476), Expect = 1e-47
Identities = 110/303 (36%), Positives = 206/303 (67%), Gaps = 29/303 (9%)
Query: 144 QVREQEGQVREQEGQVREQEGQVREQEGQV-----REQEGQVREQEGQVREQEGQMGEQE 198
Q++++ +R++ V Q Q + Q+ R QE ++REQE ++REQE ++ EQE
Sbjct: 161 QLQDETNHLRKELESVGRQL-QAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219
Query: 199 GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258
++ EQEE++ EQEE++++QEE++ EQEE++R+ EE++ EQEE++ +QEE++++QEE++
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 279
Query: 259 KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318
+QEE++ EQEE++REQEE++ EQEE++REQEE++ EQEE++REQEE+
Sbjct: 280 EQEERLCEQEERLREQEERLC-------------EQEERLREQEERLCEQEERLREQEER 326
Query: 319 MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378
+ EQE+ G +E++ E+ E++ EQ E+ +++E++ E+E +++ EE + ++E++R+Q
Sbjct: 327 LCEQEKLPG--QERLLEEVEKLLEQ-ERRQEEQERLLERERLLEEVEELL--EQERLRQQ 381
Query: 379 EEQMRKQE-----EQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
+E++ +QE E++R+ E + E + EQ+ + R E++ + + + E+ + E
Sbjct: 382 DERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 441
Query: 434 QKE 436
K+
Sbjct: 442 LKK 444
Score = 181 bits (459), Expect = 1e-45
Identities = 119/357 (33%), Positives = 218/357 (61%), Gaps = 20/357 (5%)
Query: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
N ++ E + E+ LV+ ++ + +LK + P P G + + Q++++
Sbjct: 113 NSLVRTSKEEKKHEIHLVQ----KLGRSLFKLKNQTAEPLAPEPPAGPSKVE--QLQDET 166
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEG 122
+R +E E R+ + +V + R QE ++REQE ++REQE ++REQE
Sbjct: 167 NHLR------KELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEE 220
Query: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
++ EQE ++REQE ++REQE ++ EQE ++RE E ++ EQE ++ EQE ++REQE ++ E
Sbjct: 221 RLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHE 280
Query: 183 QEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE-- 240
QE ++ EQE ++ EQE ++ EQEE++ EQEE++ +QEE++ EQEE++ +QE+ G++
Sbjct: 281 QEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLL 340
Query: 241 EQVQKQEEQVQKQEEQMRKQE-EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
E+V+K EQ ++QEEQ R E E++ E+ E++ EQE L+Q+++ +++T ++ E++R
Sbjct: 341 EEVEKLLEQERRQEEQERLLERERLLEEVEELLEQER--LRQQDERLWQQETLQELERLR 398
Query: 300 EQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE 356
E E + E + EQ + R E++ + + + ++Q+ E K+ +E + E
Sbjct: 399 ELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSE 455
Score = 179 bits (453), Expect = 6e-45
Identities = 95/233 (40%), Positives = 171/233 (73%), Gaps = 20/233 (8%)
Query: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
EQ+ ++ +RK+ E +G Q +Q + E Q R+QEE++REQEE++REQEE++
Sbjct: 160 EQLQDETNHLRKELESVGRQ---LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLR 216
Query: 280 KQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKE 338
+Q+E+ EQEE+ EQEE++REQEE++ EQEE++RE EE++ EQEE++ +QEE++ EQ+E
Sbjct: 217 EQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEE 276
Query: 339 QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
++ EQ+E++ +QEE++ EQEE++ +QEE++R+QEE++ +QEE++R+QEE++ +QE+ G+
Sbjct: 277 RLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQ 336
Query: 399 QK-----------EQMGEQKEQMREQEEQMGE-----QKEQMRKQEEHMGEQK 435
++ E+ E++E++ E+E + E ++E++R+Q+E + +Q+
Sbjct: 337 ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQE 389
Score = 172 bits (435), Expect = 7e-43
Identities = 106/305 (34%), Positives = 196/305 (64%), Gaps = 42/305 (13%)
Query: 102 QVREQEGQVREQEGQVREQEGQVREQEGQV-----REQEGQVREQEGQVREQEGQVREQE 156
Q++++ +R++ V Q Q + Q+ R QE ++REQE ++REQE ++REQE
Sbjct: 161 QLQDETNHLRKELESVGRQL-QAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219
Query: 157 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ 216
++ EQE ++REQE ++REQE ++ EQE ++RE E ++ EQE ++ EQEE++ EQEE++
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 279
Query: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE-----EQM 271
+QEE++ EQEE++R+QEE++ EQEE++++QEE++ +QEE++R+QEE++ EQE E++
Sbjct: 280 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERL 339
Query: 272 REQEEQMLKQKEQTEQEEQTGEQE------------EQMREQEEQMREQE-----EQMRE 314
E+ E++L+Q+ + E++E+ E+E E++R+Q+E++ +QE E++RE
Sbjct: 340 LEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRE 399
Query: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
E + E W E ++EQ+ + E++ + + + E+QV++ ++
Sbjct: 400 LERML-----------ELGW---EALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKS 445
Query: 375 MRKQE 379
+E
Sbjct: 446 GGAEE 450
Score = 165 bits (418), Expect = 7e-41
Identities = 97/278 (34%), Positives = 179/278 (64%), Gaps = 15/278 (5%)
Query: 171 GQVREQEGQVREQEGQVREQEGQMGEQEG---QMGEQEEQMGEQEEQMQKQE----EQMG 223
G+ R + + E Q +E + Q+ E + ++ +K E +++G
Sbjct: 75 GEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLG 134
Query: 224 EQEEQMRKQE-EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
+++ Q E + + + EQ+Q + +RK+ E + Q Q + QML
Sbjct: 135 RSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQL-QAEVENNQMLSLL 193
Query: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
+ QEE+ EQEE++REQEE++REQEE++ EQEE++REQEE++ +QEE++ EQ+E++ E
Sbjct: 194 NR-RQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252
Query: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402
+E++ +QEE++ EQEE++++QEE++ +QEE++ +QEE++R+QEE++ +QEE++ EQ+E+
Sbjct: 253 HEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEER 312
Query: 403 MGEQKEQMREQEEQMGEQ-----KEQMRKQEEHMGEQK 435
+ EQ+E++REQEE++ EQ +E++ ++ E + EQ+
Sbjct: 313 LCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQE 350
Score = 162 bits (410), Expect = 6e-40
Identities = 84/217 (38%), Positives = 154/217 (70%), Gaps = 9/217 (4%)
Query: 229 MRKQEEQMGEQEEQVQKQEEQVQKQEEQ----MRKQEEQMREQEEQMREQEEQMLKQKEQ 284
+R +E+ + VQK + K + Q + + + EQ++++ + K+ E
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELES 175
Query: 285 TEQEEQTGEQEEQM-----REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339
++ Q + QM R QEE++REQEE++REQEE++REQEE++ +QEE++ EQ+E+
Sbjct: 176 VGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEER 235
Query: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ 399
+ EQ+E++ +QEE++ E EE++ +QEE++ +QEE++R+QEE++ +QEE++ +QEE++ EQ
Sbjct: 236 LREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQ 295
Query: 400 KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+E++ EQ+E++REQEE++ EQ+E++R+QEE + EQ++
Sbjct: 296 EERLCEQEERLREQEERLCEQEERLREQEERLCEQEK 332
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 177 bits (448), Expect = 2e-44
Identities = 157/487 (32%), Positives = 268/487 (55%), Gaps = 86/487 (17%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHI----KELKRKLETDKIPLPQEGQVREQEGQVR 62
+EL++++ E EE Q E + +++ ++L ++LE +K L Q Q+ ++ +
Sbjct: 85 QELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ--QLDQELVKRD 142
Query: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR---E 119
EQ G +EQ ++ EQ QEG ++ E +QEGQ++ E +QEGQ+ +
Sbjct: 143 EQLGMKKEQLLELPEQ------QEGHLKHLE----QQEGQLKHPE----QQEGQLELPEQ 188
Query: 120 QEGQVR---EQEGQVR---EQEGQVR---EQEGQVR---EQEGQV---REQEGQVREQEG 164
QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+ ++QEGQ+ E
Sbjct: 189 QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSE- 247
Query: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE--EQMQKQEEQM 222
+QEGQ+ E +QEGQ++ E QEGQ+ EEQMG+ + EQ + Q + +
Sbjct: 248 ---QQEGQLELSE----QQEGQLKHLE----HQEGQLEVPEEQMGQLKYLEQQEGQLKHL 296
Query: 223 GEQEEQMRKQEEQMG-----EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ------M 271
+QE+Q E+QMG EQ+E K EQ + Q EQ+ +QE Q++ E+Q +
Sbjct: 297 DQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHL 356
Query: 272 REQEEQMLKQKEQTEQEEQTGEQEEQ---MREQEEQMR---EQEEQMR---EQEEQMREQ 322
QE Q+ ++Q Q +Q +Q+ Q + E+E Q++ +QE Q++ +QE Q+ +Q
Sbjct: 357 EHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQ 416
Query: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE--EQMQKQEEQVRKQEEQMRKQEE 380
E Q+ E+Q+ + K + EQ+ Q+ E+Q G+ E EQ Q + + ++E+Q+ E+
Sbjct: 417 ERQVEHLEQQVGQLK-HLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQ 475
Query: 381 Q------MRKQEEQMRKQEEQMG-----EQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Q + KQE Q+ E+Q+G EQ+E+ E EQ Q + + +Q+ Q++ E+
Sbjct: 476 QEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQ 535
Query: 430 HMGEQKE 436
G+ ++
Sbjct: 536 QKGQLEQ 542
Score = 176 bits (445), Expect = 5e-44
Identities = 159/467 (34%), Positives = 266/467 (56%), Gaps = 84/467 (17%)
Query: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVR---EQEGQVR 62
N++L+E+ L ++L E K + QL +K K + ++P QEG ++ +QEGQ++
Sbjct: 120 NKQLEEEKKLLDQQLDQ-ELVKRDEQLGMK----KEQLLELPEQQEGHLKHLEQQEGQLK 174
Query: 63 ---EQEGQVR---EQEGQVR---EQEGQVR---EQEGQVR---EQEGQVR---EQEGQV- 103
+QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+
Sbjct: 175 HPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLE 234
Query: 104 --REQEGQVR---EQEGQVR---EQEGQVRE---QEGQVR---EQEGQVR---EQEGQVR 146
++QEGQ+ +QEGQ+ +QEGQ++ QEGQ+ EQ GQ++ +QEGQ++
Sbjct: 235 LPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLK 294
Query: 147 EQEGQVREQEGQVREQEGQVR---EQEGQ---VREQEGQVR---EQEGQVR---EQEGQ- 193
+ Q ++ E +Q GQ++ +QEGQ + +QEGQ+ EQEGQ++ +QEGQ
Sbjct: 295 HLDQQEKQPE-LPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQL 353
Query: 194 --MGEQEGQMGEQEEQMGE--QEEQMQKQEEQMGEQEEQMRKQEEQMG------EQEEQV 243
+ QEGQ+G E+Q+ + Q E+ Q Q + + E+E Q++ +Q G +QE Q+
Sbjct: 354 EHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQL 413
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMR--EQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
++QE QV+ E+Q+ Q + + EQE Q++ EQ++ L+ EQ + + EQEE+ E
Sbjct: 414 EQQERQVEHLEQQV-GQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLEL 472
Query: 302 EEQMREQEEQMREQEEQMREQEEQMG-----KQEEQMWEQKEQMWEQKEQMWKQEEQMGE 356
EQ Q + + +QE Q+ E+Q+G +Q+E+ E EQ Q + + +QE Q+ +
Sbjct: 473 PEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKD 532
Query: 357 QEEQMQKQEE--------QVRKQEEQMRKQEEQMRKQEEQMRKQEEQ 395
E+Q + E+ QV+ + + + E + E Q +KQE Q
Sbjct: 533 LEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQ 579
Score = 154 bits (388), Expect = 2e-37
Identities = 139/482 (28%), Positives = 248/482 (51%), Gaps = 79/482 (16%)
Query: 21 QLVETEKSEIQLHIKELKRKLET----DKIP--LPQEGQVREQEGQVREQEGQVREQEGQ 74
+L++T + H +++K+ K+P LP E +++E + +G + EQE +
Sbjct: 18 ELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKG-LPEQECE 76
Query: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134
+++E Q +E + Q EQ + ++ E ++ + + +++ Q+ +Q + ++ Q +Q
Sbjct: 77 QQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQ 136
Query: 135 EGQVR-EQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVR---E 189
E R EQ G +EQ ++ EQ EG ++ E +QEGQ++ E +QEGQ+ +
Sbjct: 137 ELVKRDEQLGMKKEQLLELPEQQEGHLKHLE----QQEGQLKHPE----QQEGQLELPEQ 188
Query: 190 QEGQM---GEQEGQMGEQEEQMG------EQEEQMQKQEEQMG------EQEEQMRKQEE 234
QEGQ+ +QEGQ+ E+Q G +QE Q++ E+Q G +QE Q+ E+
Sbjct: 189 QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQ 248
Query: 235 QMGEQE--EQVQKQEEQVQKQEEQMRKQEEQM---------------REQEEQMREQEEQ 277
Q G+ E EQ + Q + ++ QE Q+ EEQM +Q+E+ E EQ
Sbjct: 249 QEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQ 308
Query: 278 MLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ------MREQEEQMGKQEE 331
+ Q + EQ+E + EQ Q EQ+ EQE Q++ E+Q + QE Q+G E+
Sbjct: 309 QMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQ 368
Query: 332 QMWEQKEQMWEQKEQMWKQEEQ---------------MGEQEEQMQKQEEQVRKQEEQMR 376
Q+ + K+ +Q + +EE+ + +QE Q+++QE QV E+Q+
Sbjct: 369 QVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQV- 427
Query: 377 KQEEQMRKQEEQMRKQEEQMGE---QKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
Q + + +QE Q++ E+Q G+ ++Q+G+ K EQEE+ E EQ Q +H+ +
Sbjct: 428 GQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKN--LEQEEKQLELPEQQEGQVKHLEK 485
Query: 434 QK 435
Q+
Sbjct: 486 QE 487
Score = 81.6 bits (200), Expect = 1e-15
Identities = 68/214 (31%), Positives = 114/214 (53%), Gaps = 24/214 (11%)
Query: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQE--EQMREQEEQMLKQKEQTEQEE-QTGEQE 295
Q+ V+ E KQEE+ + + EQE +Q +E +EQ L+Q+ + EE Q E
Sbjct: 45 QKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENP 104
Query: 296 EQMREQEEQMREQE--EQMREQEEQMREQ-EEQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
EQ +QE+ R+Q+ +Q+ E+++ + +Q ++++ K++EQ+ +KEQ+ E EQ +
Sbjct: 105 EQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLK 164
Query: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG-----EQKE---QMG 404
+ +QE Q+ K EQ Q E +QE Q+ E+Q G EQ+E ++
Sbjct: 165 HLEQQEGQL--------KHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELP 216
Query: 405 EQKEQMREQEEQMGEQKEQMRKQEE--HMGEQKE 436
EQ+E E EQ Q E ++QE + EQ+E
Sbjct: 217 EQQEGQLELPEQQEGQLELPQQQEGQLELSEQQE 250
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 176 bits (447), Expect = 3e-44
Identities = 141/432 (32%), Positives = 236/432 (54%), Gaps = 55/432 (12%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
EE K+++ E QE+ K Q H KE +++E EG E+ G+ E+EG
Sbjct: 700 EEWKKRDGEEQEQ-------KEREQGHQKERNQEME--------EGG-EEEHGEGEEEEG 743
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
E+E E+EG+ +E EG+ E EG+ ++EG+ +++E +E++G E+EG E
Sbjct: 744 DREEEE----EKEGEGKE-EGEGEEVEGEREKEEGERKKEERAGKEEKG---EEEGDQGE 795
Query: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
E + E G+ +E+ G+V + G+V E +G+ RE+E E+EG+ E+EG+ E+EG+
Sbjct: 796 GEEEETEGRGEEKEEGGEV--EGGEVEEGKGE-REEE----EEEGEGEEEEGEGEEEEGE 848
Query: 187 VREQEGQ-MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR---KQEEQMGEQEEQ 242
E+EG+ GE+EG+ GE EE+ GE+ E ++EE GE EE+ ++EE GE EE+
Sbjct: 849 GEEEEGEGKGEEEGEEGEGEEE-GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
+ + E +EE K EE+ E E + E+E + + + E EE+ GE E + E E
Sbjct: 908 GEGEGE----EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963
Query: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ 362
+ E+ E E+ E E+EE G+ EE+ E++ +EE GE+E + +
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE-----------GEEEGEGEEEGEGE 1012
Query: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKE 422
+EE+ + E ++ +E + +EE + E+ GE++E+ GE +E R +EE+ E+ +
Sbjct: 1013 GEEEEEGEVEGEVEGEEGEGEGEEE----EGEEEGEEREKEGEGEENRRNREEEEEEEGK 1068
Query: 423 QMRKQEEHMGEQ 434
EE Q
Sbjct: 1069 YQETGEEENERQ 1080
Score = 169 bits (428), Expect = 5e-42
Identities = 126/425 (29%), Positives = 234/425 (55%), Gaps = 22/425 (5%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
KE+N E++E + E E + +E + K K +EG+ E EG+ ++EG+ +
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK----EEGEGEEVEGEREKEEGERK 776
Query: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
++E +E++G E+EG E E + E G+ +E+ G+V E + + E + E+EG
Sbjct: 777 KEERAGKEEKG---EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833
Query: 130 QVREQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQVREQEGQVREQEGQ---VREQEG 185
+ E+EG+ E+EG+ E+EG+ + E+EG+ E E + E EG+ E+EG+ E EG
Sbjct: 834 EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG 893
Query: 186 QVREQEGQ-MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
+ E+EG+ GE+EG+ GE EE+ GE + + ++ EE GE EE+ + E + GE E + +
Sbjct: 894 EGEEEEGEGEGEEEGE-GEGEEEEGEGKGE-EEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951
Query: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
+ E + +++E + +EE E EE E EE+ + + + E+ E+ GE+E + E+ E
Sbjct: 952 EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011
Query: 305 MREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ 364
E+EE+ + E E+ E G++EE E+ E++E+ + EE +EE+ +++
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEE-----GEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 365 EEQVRKQEEQMRKQEEQMRKQEEQMR---KQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
+ EE+ +Q+ + K+ +++ K + QK+ + + +EQ +M Q
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQS 1126
Query: 422 EQMRK 426
+++ K
Sbjct: 1127 KRLLK 1131
Score = 145 bits (366), Expect = 7e-35
Identities = 131/438 (29%), Positives = 231/438 (52%), Gaps = 37/438 (8%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ-EGQVREQEGQVREQEGQV 68
KEK L ++L T+K+E+ E K K + P+ G +EG + Q
Sbjct: 620 KEKTEILSDDL----TDKAEVS----EGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQD 671
Query: 69 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-- 126
E+E +++ E+ G+ ++ + E + + E++ Q ++G +E+ ++ E
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731
Query: 127 --QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
+ G+ E+EG E+E E+EG+ +E EG+ E EG+ ++EG+ +++E +E++
Sbjct: 732 EEEHGEGEEEEGDREEEE----EKEGEGKE-EGEGEEVEGEREKEEGERKKEERAGKEEK 786
Query: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM--RKQEEQMGEQEEQ 242
G E+EG GE GE+EE G EE+ + E + GE EE R++EE+ GE EE+
Sbjct: 787 G---EEEGDQGE-----GEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
+ EE+ + EE+ + E E+E + E EE+ + + + E+EE GE EE+ E E
Sbjct: 839 EGEGEEEEGEGEEE---EGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEE-GEGE 894
Query: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ 362
+ E E + E+ E E+EE GK EE+ E+ E E++E + E+ GE EE+
Sbjct: 895 GEEEEGEGEGEEEGEGEGEEEEGEGKGEEE-GEEGEGEGEEEEGEGEGEDGEGEGEEEEG 953
Query: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQK-EQMREQEEQ---MG 418
+ E + + E + ++ E ++ E ++EE GE +E+ GE++ E+ E EE+ G
Sbjct: 954 EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEG 1013
Query: 419 EQKEQMRKQEEHMGEQKE 436
E++E+ + E GE+ E
Sbjct: 1014 EEEEEGEVEGEVEGEEGE 1031
Score = 140 bits (353), Expect = 2e-33
Identities = 105/321 (32%), Positives = 179/321 (55%), Gaps = 18/321 (5%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQ 67
E++E E +EE + E E+ E + +E + + E + +EG+ E E + E EG+
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 68 VREQEGQVR-EQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVR-EQEGQVREQEGQV 124
E+EG+ E+EG E EG+ E EG+ E+ EG+ E+EG+ + E+EG+ E EG+
Sbjct: 878 GEEEEGEGEGEEEG---EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ---EGQVREQEGQVREQEGQVR 181
E EG+ + EG+ E+EG E EG+ E EG+ E+ EG+ E EG+ E EG+
Sbjct: 935 EEGEGEGEDGEGEGEEEEG---EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGE 991
Query: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE-EQMGEQE--EQMRKQEEQMGE 238
E+EG+ +E GE+EG+ +EE+ GE E +++ +E E GE+E E+ ++ E+ GE
Sbjct: 992 EEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGE 1051
Query: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
EE + +EE+ +EE+ + QE E E Q E+ +++ K K + + Q++ +
Sbjct: 1052 GEENRRNREEE---EEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSV 1108
Query: 299 REQEEQMREQEEQMREQEEQM 319
+ +EQ +M Q +++
Sbjct: 1109 TNTQGNGKEQRSKMPVQSKRL 1129
Score = 139 bits (349), Expect = 7e-33
Identities = 129/458 (28%), Positives = 233/458 (50%), Gaps = 37/458 (8%)
Query: 2 PRITNEELKEKNAELQEELQLVET------EKSEIQLHIKELK----RKLETDKIPLPQE 51
P T E ++ E+ EE + E E+ E++ + + +K RK +T+ +
Sbjct: 572 PATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLT 631
Query: 52 GQVREQEGQVRE----QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 107
+ EG+ + ++G +G E + + RE+ + + + R E
Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691
Query: 108 GQ---VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 164
G+ ++E + R+ E Q +++ Q ++E +EG E+ G+ E+EG E+E
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG-EEEHGEGEEEEGDREEEE- 749
Query: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQE--EQMGEQEEQMQKQEEQM 222
E+EG+ +E EG+ E EG+ ++EG+ ++E + G++E E+ G+Q E +++ E
Sbjct: 750 ---EKEGEGKE-EGEGEEVEGEREKEEGERKKEE-RAGKEEKGEEEGDQGEGEEEETEGR 804
Query: 223 GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
GE++E+ E + GE EE ++EE EE+ + EE+ E EE+ E EE+ + K
Sbjct: 805 GEEKEE--GGEVEGGEVEEGKGEREE-----EEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857
Query: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK-QEEQMWEQKEQMW 341
+ E EE GE+E + E E + E E + E+ E E+EE G+ +EE E +E+
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917
Query: 342 EQK-EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
E K E+ ++ E GE+EE + E+ + EE+ + E + + E + ++ E GE+
Sbjct: 918 EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEG 977
Query: 401 EQMGEQKEQMREQEEQMGEQ--KEQMRKQEEHMGEQKE 436
E GE++E E EE+ GE+ +E+ +EE GE +E
Sbjct: 978 EGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015
Score = 125 bits (314), Expect = 8e-29
Identities = 101/305 (33%), Positives = 163/305 (53%), Gaps = 32/305 (10%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQ 67
E +E+ E +EE E E+ E + E K + E ++ +EG+ E EG+ E EG+
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGE 886
Query: 68 VREQ---EGQVREQEGQVREQ-EGQVREQEGQVR-EQEGQVREQEGQVREQEGQVREQEG 122
E+ EG+ E EG+ E+ EG+ E+EG+ + E+EG+ E EG+ E EG+ + EG
Sbjct: 887 GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEG 946
Query: 123 QVREQEGQ----VREQEGQVREQ---EGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 175
+ E+EG+ E EG+ E+ EG+ E EG+ E EG+ E+EG+ +E E
Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 176 QEGQ---VREQEGQVR-EQEGQMGEQEGQM------GEQEEQMGEQEEQMQKQEEQMGE- 224
+EG+ E+EG+V E EG+ GE EG+ GE+ E+ GE EE + +EE+ E
Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 225 ---QEEQMRKQEEQMGEQEEQVQKQEEQVQ------KQEEQMRKQEEQMREQEEQMREQE 275
QE + E Q GE+ ++V K + V+ Q++ + + +EQ +M Q
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQS 1126
Query: 276 EQMLK 280
+++LK
Sbjct: 1127 KRLLK 1131
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/265 (21%), Positives = 125/265 (47%), Gaps = 30/265 (11%)
Query: 201 MGEQEEQMGEQEEQMQKQEEQMGE-QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259
+ E+ + Q QK+++ +GE ++ + + E EE + +E + KQ
Sbjct: 508 LNSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGI 567
Query: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ----------E 309
Q E ++E ++ ++KE E + G +E+++ EE ++
Sbjct: 568 FMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILS 627
Query: 310 EQMREQEEQMREQEEQMGKQEE-----------------QMWEQKEQMWEQKEQMWKQEE 352
+ + ++ E + + +G+ E+ + W+ +E+ +K++ + E
Sbjct: 628 DDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEME 687
Query: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE 412
+ GE E+++ ++EE ++ E+ ++E + Q+E+ ++ EE GE++ GE++E RE
Sbjct: 688 RPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEG-GEEEHGEGEEEEGDRE 746
Query: 413 QEEQM-GEQKEQMRKQEEHMGEQKE 436
+EE+ GE KE+ +E +KE
Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKE 771
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 154 bits (390), Expect = 1e-37
Identities = 81/444 (18%), Positives = 265/444 (59%), Gaps = 18/444 (4%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE- 65
E+L + +L E ++++ +K +L +E K+ E +E Q +++E E+E
Sbjct: 1494 EKLHQAGEKLSPEEEMLQEDK---KLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEV 1550
Query: 66 -GQVREQEGQVREQEGQVREQEGQVREQEGQVR------EQEGQVREQEGQVREQEGQVR 118
+ E+E QV E++ ++E+ R + R ++E ++ ++E ++ ++E Q+
Sbjct: 1551 SREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLA 1610
Query: 119 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178
++E ++ + ++ + + ++ + EG+ ++E + ++ ++ ++ ++ ++ ++ ++
Sbjct: 1611 QEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWE 1670
Query: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
+V +E ++ ++ G++ E + + ++ E++ ++E+ + QE+++ ++ E++ E++
Sbjct: 1671 KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSW 1730
Query: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE-EQTGEQEEQ 297
+EE++ ++E ++ ++++++ ++EE + Q E++ E+E ++ +++E QE E+ + +E+
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790
Query: 298 MREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE------QKEQMWEQKEQMWKQE 351
M E+EE++ + EQ+ E++ ++ ++ E+ E++ + QK+ + ++K+ + +++
Sbjct: 1791 MPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEK 1850
Query: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
E++ +++E + +E++ ++Q+ + + ++ + + + EE++ ++KE + ++KE++
Sbjct: 1851 EKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLA 1910
Query: 412 EQEEQMGEQKEQMRKQEEHMGEQK 435
E E+++ + ++ + K++E + ++K
Sbjct: 1911 ETEKKLVQVEDSLAKKQEKLAQEK 1934
Score = 148 bits (374), Expect = 8e-36
Identities = 68/435 (15%), Positives = 261/435 (60%), Gaps = 16/435 (3%)
Query: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
+ E +EK ++ EE + ++ E ++H +++ +K +E ++ ++E ++ ++E
Sbjct: 1551 SREGEEKEQQVTEEQRHIQEEHKWARIH----RKRARAEKKRAQEERKLAQEEEKLAQEE 1606
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
Q+ ++E ++ + ++ + + ++ + EG+ ++E + ++ ++ ++ ++ ++ ++
Sbjct: 1607 RQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLA 1666
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
++ +V +E ++ ++ G++ E + + ++ ++ ++E + QE ++ ++ ++
Sbjct: 1667 KKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDME 1726
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
++ +E ++ ++EG++ E+++++ E+EE + Q E++ E+E ++ ++EE + +++E++ +
Sbjct: 1727 ELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQ 1786
Query: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305
+E++ ++EE++ ++ EQ+ E++ ++ ++ E+ + E+ + + + Q++ +
Sbjct: 1787 HKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEEL-------TKNKMILYQKKNL 1839
Query: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE 365
++++ + +++E++ +++E + +E++ K+Q+ + K ++ + + + EE++ +++
Sbjct: 1840 AQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEK 1899
Query: 366 EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGE-----Q 420
E V K++E++ + E+++ + E+ + K++E++ ++K ++ +K ++ ++ GE +
Sbjct: 1900 ETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKE 1959
Query: 421 KEQMRKQEEHMGEQK 435
++ + + + + E+K
Sbjct: 1960 EKALNLEMKRLAEEK 1974
Score = 129 bits (324), Expect = 5e-30
Identities = 110/522 (21%), Positives = 254/522 (48%), Gaps = 123/522 (23%)
Query: 35 KELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 94
K L L+ D +P P++ + QEG +RE Q QE +R +E RE+E ++
Sbjct: 1299 KVLLEDLDWDVVP-PEKKPIFIQEGAIREDMIQGVTQE-VIRHKEVMPREEEQAQKKARD 1356
Query: 95 QVREQEGQVREQEGQV-----------------REQEGQVREQEGQVR---EQEGQVREQ 134
+ +E QV ++G+ +E++ ++ Q R ++E +V +
Sbjct: 1357 MLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKI 1416
Query: 135 EGQVREQEGQVREQEGQVREQEGQVREQEGQV-------------------REQEGQVRE 175
+ ++ ++E + E+ ++ E +V +QEG++ ++ G+ R+
Sbjct: 1417 KREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRK 1476
Query: 176 QEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ--------------KQEEQ 221
+E+ + QE + Q G+ EE+M +++++++ K +EQ
Sbjct: 1477 SWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQ 1536
Query: 222 MGEQEEQMRKQEE--QMGEQEEQVQKQE--------------------EQVQKQEEQMRK 259
+ EE++ +EE + GE++EQ +E E+ + QEE+
Sbjct: 1537 QYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLA 1596
Query: 260 QEEQMREQEEQMREQEEQMLKQ---------KEQTEQEEQTGEQEEQMREQEEQMREQEE 310
QEE+ QEE+ QEE+ L Q +E + E + ++EE + ++ E++ ++ E
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656
Query: 311 QMREQEEQMREQEEQMGKQEEQM-----------------------------WEQKEQM- 340
++ ++ +++ ++ E++ ++EE++ W++KE
Sbjct: 1657 KLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQ 1716
Query: 341 ------WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEE 394
W+ +E WK EE++ ++E ++ ++++++ ++EE + Q E++ ++E ++ ++EE
Sbjct: 1717 ELEELEWDMEELSWK-EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEE 1775
Query: 395 QMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+ ++KE++ + KE+M E+EE++G ++EQ+ +++ + +++E
Sbjct: 1776 LLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRE 1817
Score = 124 bits (312), Expect = 1e-28
Identities = 75/428 (17%), Positives = 245/428 (57%), Gaps = 17/428 (3%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELK--RKLETDKIPLPQEGQVREQEGQVREQEGQ 67
+E+ QEE QL + E+ Q ++K + R++ + Q+ + Q G+ QE +
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656
Query: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
++ ++ ++ ++ +V +E ++ ++ G++ E + + ++ ++ ++E + Q
Sbjct: 1657 ------KLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQ 1710
Query: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
E ++ ++ ++ ++ +E ++ ++EG++ E++ ++ E+E + Q ++ E+E ++
Sbjct: 1711 EKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKL 1770
Query: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
++E + +++ ++ + +E+M E+EE++ ++ EQ+ E++ ++ ++ E+ E++ K
Sbjct: 1771 AQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTK-N 1829
Query: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE 307
+ + Q++ + ++++ + +++E++ +++E +L KE+ ++Q+ + + ++
Sbjct: 1830 KMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLT------HSKKQLVQVKNKLGM 1883
Query: 308 QEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ 367
+ + + EE++ +++E + K++E++ E ++++ + ++ + K++E++ +E+M+ E+
Sbjct: 1884 FNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLA--QEKMKLALEK 1941
Query: 368 VRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ 427
Q ++ + E + K+E+ + + +++ E+K ++ E KE + + E ++ +M +
Sbjct: 1942 AMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQV 2001
Query: 428 EEHMGEQK 435
E+ + E+K
Sbjct: 2002 EQELFERK 2009
Score = 121 bits (303), Expect = 1e-27
Identities = 92/449 (20%), Positives = 240/449 (53%), Gaps = 23/449 (5%)
Query: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLH--IKELKRKLETDKIPLPQEGQVREQE 58
+ ++ + +EK ++++ +L ETEK +Q+ + + + KL +K+ L E + + +
Sbjct: 1888 LAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGK 1947
Query: 59 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 118
++R + +E++ E + R E ++R EG+ +G+ E Q + + +
Sbjct: 1948 KRLRGELDIAKEEKALNLEMK---RLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQE 2004
Query: 119 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ---VREQEGQVREQEGQVRE 175
E ++ +E + ++ + +E ++ + G++ GQ V+ Q + +++
Sbjct: 2005 LFERKLSLEEKILLHEDRILAMEESEIAK--GKLEFTRGQRIFVQGQRKLAKASRKLIKK 2062
Query: 176 QEGQVREQE--GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE 233
+E +E ++ + ++ E ++ ++E +M + + + +E ++ ++ ++ +E
Sbjct: 2063 RESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKE 2122
Query: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT--EQEEQT 291
E+ ++ K E+++ +++ ++ + +M +EE+M E+E ++ ++ + + EE+
Sbjct: 2123 WDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEG 2182
Query: 292 G-EQEEQMREQEEQMREQEEQMR--EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMW 348
G E+EE + + + R+++E R + +E+ Q +++ +E E + + E ++Q
Sbjct: 2183 GIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQES 2242
Query: 349 KQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEE----QMRKQEEQMRKQEEQMGEQKEQMG 404
E+ E+EE+ +++EE+VR++EE+ +++EE Q+ K+EE+ +K++++ ++KE++
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE--KKKEEVQ 2300
Query: 405 EQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
E++E E+EE M E++ + EE E
Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEEE 2329
Score = 118 bits (295), Expect = 1e-26
Identities = 91/448 (20%), Positives = 237/448 (52%), Gaps = 32/448 (7%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG--- 66
KEK AE +++L VE ++ Q + + K KL +K + + ++R + +E++
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL 1965
Query: 67 -QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
R E ++R EG+ +G+ E Q + + + E ++ +E + ++ +
Sbjct: 1966 EMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILA 2025
Query: 126 EQEGQVREQEGQVREQEGQ---VREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQV 180
+E ++ + G++ GQ V+ Q + ++++E +E ++ + ++
Sbjct: 2026 MEESEIAK--GKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKL 2083
Query: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
E ++ ++E +M + + + +E ++ ++ ++ +E E+ ++ K E+++ ++
Sbjct: 2084 TRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQ 2143
Query: 241 EQ--------VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQKEQTEQEE 289
+ + K+E+ +++ + RK E + + EE+ +EE++ LK++ + +E
Sbjct: 2144 RKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEA 2203
Query: 290 QTGEQ-EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMW 348
+ G++ +E+ Q +++ +E E E + E E+Q E+ E++E+ ++E++
Sbjct: 2204 KRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVR 2263
Query: 349 KQEEQMGEQEE----QMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM- 403
++EE+ E+EE Q++K+EE+ +K++++ K++E+++++EE ++EE M E++ +
Sbjct: 2264 EEEEERKEEEEGEEKQVEKEEEEKKKKKKE--KKKEEVQEKEEVFEEKEEIMSEEETESL 2321
Query: 404 --GEQKEQMREQEEQMGEQKEQMRKQEE 429
E++E+ EE++ +KE ++K+++
Sbjct: 2322 SDEEEEEESCSLEEEVDREKEILKKEKQ 2349
Score = 103 bits (257), Expect = 3e-22
Identities = 94/465 (20%), Positives = 240/465 (51%), Gaps = 42/465 (9%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ--EGQVREQEGQVREQEGQ 67
KEK A+ +E L + + + + ++K KL L Q E +E+E ++++E
Sbjct: 1850 KEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKL 1909
Query: 68 VREQEGQVREQEGQVREQEGQVREQ-----EGQVREQEGQVREQEGQVREQEG----QVR 118
++ V+ ++ ++QE +E+ E + + + ++R + +E++ R
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKR 1969
Query: 119 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178
E ++R EG+ +G+ E Q + + + E ++ +E + ++ + +E
Sbjct: 1970 LAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEES 2029
Query: 179 QVREQEGQVREQEGQMGEQEGQ--MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK---QE 233
++ + G++ GQ +GQ + + ++ ++ E + K+ ++ + + ++K E
Sbjct: 2030 EIAK--GKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDE 2087
Query: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK-QKEQTEQEEQTG 292
++ ++E ++ K + + +E ++ ++ ++ +E E+ ++ K +K+ ++ +
Sbjct: 2088 RKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLA 2147
Query: 293 EQEEQMREQEEQMREQEEQM-REQEEQMREQEEQMGKQEEQMWEQKEQMWEQ-------- 343
+ +M +EE+M E+E ++ R+ E + + EE+ G +EE++ ++ W +
Sbjct: 2148 NKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGD 2207
Query: 344 --KEQMWKQEEQMGEQE---EQMQKQEEQVRKQE----EQMRKQEEQMRKQEEQMRKQEE 394
KE+ Q +++ +E E+M+ +++ KQE E+ ++EE+ ++EE++R++EE
Sbjct: 2208 KPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267
Query: 395 QMGEQKEQMGEQKEQMREQEEQMGEQKEQMR---KQEEHMGEQKE 436
+ E++E GE+K+ +E+EE+ ++KE+ + +++E + E+KE
Sbjct: 2268 ERKEEEE--GEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKE 2310
Score = 82.8 bits (203), Expect = 6e-16
Identities = 80/383 (20%), Positives = 190/383 (49%), Gaps = 43/383 (11%)
Query: 1 MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
+ ++T +E K QEE+++ + +++ L +KE + +E K+ + +E E+ +
Sbjct: 2080 LQKLTRDERKLT----QEEIKMTKMKRA---LFVKERRLSIEQSKLDI-KEWDFSEKRSE 2131
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV---REQEGQVREQE--- 114
+ + E ++ ++ ++ + ++ +E ++ E+E ++ + +V E+EG + E+E
Sbjct: 2132 LTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIP 2191
Query: 115 ---GQVREQEGQVR---------EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 162
+ R+++ R Q +V +E E E + E E Q + E+
Sbjct: 2192 FLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEER 2251
Query: 163 EGQVREQEGQVREQEGQVREQE-GQVREQEGQMGEQEGQMGEQE-EQMGEQEEQMQKQEE 220
E + +E +VRE+E + +E+E G+ ++ E + E++ + E++ E++ E+EE +++EE
Sbjct: 2252 EEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEE 2311
Query: 221 QMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280
M E+E + E E+EE+ EE+V +++E ++K E++ +++EQ + L+
Sbjct: 2312 IMSEEETESLSDE----EEEEESCSLEEEVDREKEILKK------EKQFKLQEQRRKSLR 2361
Query: 281 QKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
+E+ + + + ++ +++ +M+E+ +++ WE K+
Sbjct: 2362 GRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKKAT 2421
Query: 341 WEQKEQ-----MWKQEEQMGEQE 358
+ + M K+ E MG+ E
Sbjct: 2422 VVEIPRKFLGTMDKEREVMGKYE 2444
Score = 33.1 bits (74), Expect = 0.51
Identities = 29/215 (13%), Positives = 88/215 (40%), Gaps = 22/215 (10%)
Query: 214 QMQKQEEQMGEQEEQMRKQE---EQMGEQEEQVQKQEEQVQKQEEQ----MRKQEEQMRE 266
Q+ +++E E ++QM +E +G + +Q QV+++ + + E+
Sbjct: 991 QLTQKQETFREMQQQMIGEEPLDHLLGMRATDLQILSTQVEQRLNENLTLSHRDEKPAFS 1050
Query: 267 QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326
+ M + + LK +E+ E + + R + +++ ++ ++ +E++ +
Sbjct: 1051 LDVSMPSELKSSLKPPTVSEESEVAIKPSKGQRRGQAGVKKHSQKWLRGLKKTKERDSKQ 1110
Query: 327 GKQEEQMWEQKE---------------QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ 371
E + E + W + K + + QE+ + K + +
Sbjct: 1111 MSTEPGLLEDESGTEAAPIEMEEASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLK 1170
Query: 372 EEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ 406
Q + + + ++++K+ ++ G++ + + E+
Sbjct: 1171 RLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINEE 1205
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 152 bits (383), Expect = 8e-37
Identities = 98/413 (23%), Positives = 230/413 (55%), Gaps = 14/413 (3%)
Query: 6 NEELKE-KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ 64
NE ++ K + Q E QL E +K+ ++H ++++ LET I ++ ++ +
Sbjct: 89 NENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQ-LETINILTLEKADLKTT---LYHT 144
Query: 65 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
+ R E + ++ G+++ +++E E + Q +E++ +E ++ + Q
Sbjct: 145 KRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQQT 204
Query: 125 REQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
++ + QV E QV+ E++ + +G+ + ++ + + R + + +
Sbjct: 205 IKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRD 264
Query: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
+++E E + E + QM E + EQ+ ++ + +R++ E + E ++
Sbjct: 265 IHRIQELERSLSELKNQMAEPPSLA---PPAVTSVVEQLQDEAKHLRQEVEGL---EGKL 318
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQE 302
Q Q E Q ++Q+++++EQEE +REQE Q ++++E+ EQ E+ EQ++ ++EQ
Sbjct: 319 QSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQG 378
Query: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG-EQEEQM 361
E++R+QE+++R+QEE++R++EE++ KQE+++W+Q+E++W+++E++ KQEE++ Q ++
Sbjct: 379 ERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKL 438
Query: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE 414
KQ + + E + +++ + E+Q+++ +E++ E+ + Q+ Q E +
Sbjct: 439 DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491
Score = 132 bits (331), Expect = 8e-31
Identities = 96/437 (21%), Positives = 228/437 (52%), Gaps = 17/437 (3%)
Query: 2 PRITNEELKEKNAELQEELQLVETEKSE-IQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
P + E + K A +++L+ + KS I K K+K TD P G
Sbjct: 11 PMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKK--TDSSPETTTSGGGHSPGD 68
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+ QE V + V Q+ E +++Q+ QV Q + ++ ++ + + + E
Sbjct: 69 SQYQELAVALESSSVTIN--QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLET 126
Query: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 176
+ ++ ++ + R E + ++ G+++ +++E E + Q +E+
Sbjct: 127 INILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEE 186
Query: 177 EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ-EEQ 235
+ +E ++ + Q ++ + Q+ E +Q+Q + ++ + + R + +E+
Sbjct: 187 DRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQER 246
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE 295
M + + + +E+ ++ ++++ E + E + QM E L T EQ ++
Sbjct: 247 MWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS--LAPPAVTSVVEQLQDEA 304
Query: 296 EQMREQEEQMREQEEQMREQEEQM----REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
+ +R++ E + + + E + + +EQ++++ +QEE + EQ+ Q ++E++ +Q
Sbjct: 305 KHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQN 364
Query: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
E++ EQ++ +Q+Q E++RKQE+++RKQEE++RK+EE+++KQE+++ +Q+E++ +++E+++
Sbjct: 365 ERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQ 424
Query: 412 EQEEQMG-EQKEQMRKQ 427
+QEE++ Q ++ KQ
Sbjct: 425 KQEERLALSQNHKLDKQ 441
Score = 120 bits (302), Expect = 2e-27
Identities = 78/344 (22%), Positives = 186/344 (54%), Gaps = 21/344 (6%)
Query: 109 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR----EQEG 164
Q+ E +++Q+ QV Q + ++ ++ + + + E + ++ ++ +
Sbjct: 87 QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKR 146
Query: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE 224
R E + ++ G+++ +++E E + Q E++ +E +Q++ +Q +
Sbjct: 147 AARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQQTIK 206
Query: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQK--QEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
+ + Q+ E +QVQ + ++ K + E+ R QE + E +EE+
Sbjct: 207 ERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIH 266
Query: 283 EQTEQEEQTGEQEEQMREQEE----QMREQEEQMREQEEQMREQEEQM-GKQEEQMW--- 334
E E E + QM E + EQ++++ + +R++ E + GK + Q+
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326
Query: 335 -------EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
EQK+++ EQ+E + +QE Q ++E++ +Q E++R+Q++ +++Q E++RKQE+
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQ 386
Query: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
++RKQEE++ +++E++ +Q++++ +QEE++ +++E+++KQEE +
Sbjct: 387 RLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430
Score = 117 bits (294), Expect = 2e-26
Identities = 94/419 (22%), Positives = 209/419 (49%), Gaps = 30/419 (7%)
Query: 12 KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQ 71
+ A LQ LQ E++ + H+ ++ L+ ++ L ++ + +G+ + ++ +
Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLK--QVQLERDEYAKHIKGERARWQERMWKM 250
Query: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQ 130
+ R + + + +++E E + E + Q+ E V EQ + + + +
Sbjct: 251 SVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQE 310
Query: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190
V EG+++ Q + +EQ+ +++EQE +REQE Q +VREQE ++ EQ
Sbjct: 311 VEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQ------RVREQE-RLCEQ 363
Query: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
++ EQ+ + EQ E++ +QE++++KQEE++ ++EE+++KQE+++ +QEE++ K+EE++
Sbjct: 364 NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERL 423
Query: 251 QKQEEQMRKQEEQMREQE--EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ 308
QKQEE++ + +++ E E+ ++K + E+Q E +E++ E+ + Q
Sbjct: 424 QKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQ 483
Query: 309 EEQMREQE-------------EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
Q E + + + +EE+ + + E E E ++
Sbjct: 484 RNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESR-EATSSFMDLPKEKA 542
Query: 356 EQEEQMQKQE---EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
+ EQ++++E Q + MR+ Q + ++M E ++ +++E+M+
Sbjct: 543 DGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMK 600
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 150 bits (380), Expect = 2e-36
Identities = 98/413 (23%), Positives = 229/413 (55%), Gaps = 14/413 (3%)
Query: 6 NEELKE-KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ 64
NE ++ K + Q E QL E +K+ ++H ++++ LET I ++ ++ +
Sbjct: 89 NENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQ-LETINILTLEKADLKTT---LYHT 144
Query: 65 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
+ R E + ++ G+++ ++E E + Q +E++ +E ++ + Q
Sbjct: 145 KRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRLQQT 204
Query: 125 REQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
++ + QV E QV+ E++ + +G+ + ++ + + R + + +
Sbjct: 205 IKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRD 264
Query: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
+++E E + E + QM E + EQ+ ++ + +R++ E + E ++
Sbjct: 265 IHRIQELERSLSELKNQMAEPPSLA---PPAVTSVVEQLQDEAKHLRQEVEGL---EGKL 318
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQE 302
Q Q E Q ++Q+++++EQEE +REQE Q ++++E+ EQ E+ EQ++ ++EQ
Sbjct: 319 QSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQG 378
Query: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG-EQEEQM 361
E++R+QE+++R+QEE++R++EE++ KQE+++W+Q+E++W+++E++ KQEE++ Q ++
Sbjct: 379 ERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKL 438
Query: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE 414
KQ + + E + +++ + E+Q+++ +E++ E+ + Q+ Q E +
Sbjct: 439 DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491
Score = 130 bits (328), Expect = 2e-30
Identities = 96/437 (21%), Positives = 227/437 (51%), Gaps = 17/437 (3%)
Query: 2 PRITNEELKEKNAELQEELQLVETEKSE-IQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
P + E + K A +++L+ + KS I K K+K TD P G
Sbjct: 11 PMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKK--TDSSPETTTSGGGHSPGD 68
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+ QE V + V Q+ E +++Q+ QV Q + ++ ++ + + + E
Sbjct: 69 SQYQELAVALESSSVTIN--QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLET 126
Query: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 176
+ ++ ++ + R E + ++ G+++ ++E E + Q +E+
Sbjct: 127 INILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEE 186
Query: 177 EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ-EEQ 235
+ +E ++ + Q ++ + Q+ E +Q+Q + ++ + + R + +E+
Sbjct: 187 DRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQER 246
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE 295
M + + + +E+ ++ ++++ E + E + QM E L T EQ ++
Sbjct: 247 MWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS--LAPPAVTSVVEQLQDEA 304
Query: 296 EQMREQEEQMREQEEQMREQEEQM----REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
+ +R++ E + + + E + + +EQ++++ +QEE + EQ+ Q ++E++ +Q
Sbjct: 305 KHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQN 364
Query: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
E++ EQ++ +Q+Q E++RKQE+++RKQEE++RK+EE+++KQE+++ +Q+E++ +++E+++
Sbjct: 365 ERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQ 424
Query: 412 EQEEQMG-EQKEQMRKQ 427
+QEE++ Q ++ KQ
Sbjct: 425 KQEERLALSQNHKLDKQ 441
Score = 119 bits (298), Expect = 5e-27
Identities = 78/344 (22%), Positives = 185/344 (53%), Gaps = 21/344 (6%)
Query: 109 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR----EQEG 164
Q+ E +++Q+ QV Q + ++ ++ + + + E + ++ ++ +
Sbjct: 87 QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKR 146
Query: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE 224
R E + ++ G+++ ++E E + Q E++ +E +Q++ +Q +
Sbjct: 147 AARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRLQQTIK 206
Query: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQK--QEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
+ + Q+ E +QVQ + ++ K + E+ R QE + E +EE+
Sbjct: 207 ERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIH 266
Query: 283 EQTEQEEQTGEQEEQMREQEE----QMREQEEQMREQEEQMREQEEQM-GKQEEQMW--- 334
E E E + QM E + EQ++++ + +R++ E + GK + Q+
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326
Query: 335 -------EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
EQK+++ EQ+E + +QE Q ++E++ +Q E++R+Q++ +++Q E++RKQE+
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQ 386
Query: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
++RKQEE++ +++E++ +Q++++ +QEE++ +++E+++KQEE +
Sbjct: 387 RLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430
Score = 117 bits (294), Expect = 2e-26
Identities = 94/419 (22%), Positives = 209/419 (49%), Gaps = 30/419 (7%)
Query: 12 KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQ 71
+ A LQ LQ E++ + H+ ++ L+ ++ L ++ + +G+ + ++ +
Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLK--QVQLERDEYAKHIKGERARWQERMWKM 250
Query: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQ 130
+ R + + + +++E E + E + Q+ E V EQ + + + +
Sbjct: 251 SVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQE 310
Query: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190
V EG+++ Q + +EQ+ +++EQE +REQE Q +VREQE ++ EQ
Sbjct: 311 VEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQ------RVREQE-RLCEQ 363
Query: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
++ EQ+ + EQ E++ +QE++++KQEE++ ++EE+++KQE+++ +QEE++ K+EE++
Sbjct: 364 NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERL 423
Query: 251 QKQEEQMRKQEEQMREQE--EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ 308
QKQEE++ + +++ E E+ ++K + E+Q E +E++ E+ + Q
Sbjct: 424 QKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQ 483
Query: 309 EEQMREQE-------------EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
Q E + + + +EE+ + + E E E ++
Sbjct: 484 RNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESR-EATSSFMDLPKEKA 542
Query: 356 EQEEQMQKQE---EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
+ EQ++++E Q + MR+ Q + ++M E ++ +++E+M+
Sbjct: 543 DGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMK 600
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 150 bits (378), Expect = 3e-36
Identities = 98/413 (23%), Positives = 229/413 (55%), Gaps = 14/413 (3%)
Query: 6 NEELKE-KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ 64
NE ++ K + Q E QL E +K+ ++H +++R LET I ++ ++ +
Sbjct: 89 NENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMER-LETINILTLEKADLKTT---LYHT 144
Query: 65 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
+ R E + ++ G+++ +++E E + Q +E++ +E + + Q
Sbjct: 145 KRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRLQQT 204
Query: 125 REQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
++ + QV E QV+ E++ + +G+ + ++ + + R + + +
Sbjct: 205 IKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRD 264
Query: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
+++E E + E + QM + + EQ+ ++ + +R++ E + E ++
Sbjct: 265 IHRIQELERSLSELKNQMAKPPSLA---PPAVTSVVEQLQDEAKHLRQEVEGL---EGKL 318
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQE 302
Q Q E Q ++Q+++++EQEE +REQE Q ++++E+ EQ E+ EQ++ ++EQ
Sbjct: 319 QSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQG 378
Query: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG-EQEEQM 361
E++R+QE+++R+QEE++R++EE++ KQE+++W+Q+E++W+++E++ KQEE++ Q ++
Sbjct: 379 ERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKL 438
Query: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE 414
KQ + + E + +++ + E+Q+++ +E++ E+ + Q+ Q E +
Sbjct: 439 DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQ 491
Score = 131 bits (330), Expect = 1e-30
Identities = 108/473 (22%), Positives = 238/473 (50%), Gaps = 48/473 (10%)
Query: 2 PRITNEELKEKNAELQEELQLVETEKSE-IQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
P + E + K A +++L+ + KS I K K+K TD P G
Sbjct: 11 PMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKK--TDSSPETTTSGGGHSPGD 68
Query: 61 VREQEGQVREQEG-----QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 115
+ QE V + Q+ E +++Q+ QV Q + ++ ++ + + + E
Sbjct: 69 SQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETIN 128
Query: 116 QVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 171
+ ++ ++ + R E + ++ G+++ +++E E + Q +E++
Sbjct: 129 ILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDR 188
Query: 172 QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ--------EEQMG 223
+E + + Q ++ + Q+ E +Q+ + ++ K +E+M
Sbjct: 189 SSSCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMW 248
Query: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE-----------EQMREQEEQMR 272
+ + R +E+ ++Q+ E + + + QM K EQ++++ + +R
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLR 308
Query: 273 EQEEQMLKQKEQTEQEEQTG------EQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326
QE + L+ K Q++ E EQ+++++EQEE +REQE Q ++E++ EQ E++
Sbjct: 309 -QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERL 367
Query: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE 386
+Q++ + EQ E++ +Q++++ KQEE++ ++EE++QKQE+++ QEE++ K+EE+++KQE
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE 427
Query: 387 EQM-----RKQEEQMGEQK---EQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
E++ K ++Q+ E + E + +K+ + E+Q+ E +E++ EEH+
Sbjct: 428 ERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHL 478
Score = 114 bits (284), Expect = 2e-25
Identities = 92/419 (21%), Positives = 209/419 (49%), Gaps = 30/419 (7%)
Query: 12 KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQ 71
+ A L LQ E++ + H+ ++ L+ ++ L ++ + +G+ + ++ +
Sbjct: 193 REAVLHRRLQQTIKERALLNAHVTQVTESLK--QVQLERDEYAKHIKGERARWQERMWKM 250
Query: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQ 130
+ R + + + +++E E + E + Q+ + V EQ + + + +
Sbjct: 251 SVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQE 310
Query: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190
V EG+++ Q + +EQ+ +++EQE +REQE Q +VREQE ++ EQ
Sbjct: 311 VEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQ------RVREQE-RLCEQ 363
Query: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
++ EQ+ + EQ E++ +QE++++KQEE++ ++EE+++KQE+++ +QEE++ K+EE++
Sbjct: 364 NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERL 423
Query: 251 QKQEEQMRKQEEQMREQE--EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ 308
QKQEE++ + +++ E E+ ++K + E+Q E +E++ E+ + Q
Sbjct: 424 QKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQ 483
Query: 309 EEQMREQE-------------EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
+ Q E + + + +EE+ + + E E E ++
Sbjct: 484 QNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESR-EATSSFMDLPKEKA 542
Query: 356 EQEEQMQKQE---EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
+ EQ++++E Q + MR+ Q + ++M E ++ +++E+M+
Sbjct: 543 DGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMK 600
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 148 bits (374), Expect = 8e-36
Identities = 101/430 (23%), Positives = 224/430 (52%), Gaps = 25/430 (5%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E ++K E + E + E E + +E R + D+ Q + +E+E Q +
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
+ RE+E +++ + E+EG+ G+ R+ +GQ RE+E Q R+ E + Q + R+
Sbjct: 115 RQREKERNRQKERERETEREGE----RGRDRQTDGQ-RERERQ-RDAEKERERQTDRERQ 168
Query: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
++ + Q+ + RE+ Q R + + RE+E + ++ + G+ RE+E + + +
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE----RGRERERERETETETER 224
Query: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
R+ + + Q E+E+Q E+E +++ E+ E+E + + ++ Q+E+ ++
Sbjct: 225 KRQTDRERDRQRKTEREREKQ-AERERASERETERDKERERERDRDRDRDRRQKERERQT 283
Query: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
+ + Q++ E+ R+ E + Q E+ RE+E +K + E+E + E+E Q + ++ +
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERN---RKRERERERER-ERERQRETERDREK 339
Query: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
E+E + + Q E RE+ Q G++ + E++ + ++++ +E + E++ +Q+E
Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKE 399
Query: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRK 426
+ R Q E+ R + + KQ E+ + +E + G +E+ RE+E+Q G ++++ R+
Sbjct: 400 RER-QTEKDRDGQRETEKQREREKDRESERG---------RERGREREKQKGRERDRERQ 449
Query: 427 QEEHMGEQKE 436
+ G Q++
Sbjct: 450 TDRQAGRQRK 459
Score = 139 bits (349), Expect = 7e-33
Identities = 91/404 (22%), Positives = 219/404 (54%), Gaps = 16/404 (3%)
Query: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
R T E K +E+ + + ++ + +E +R+ +TD+ Q + R ++ + R
Sbjct: 69 RQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE-R 127
Query: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122
E+E + + G+ R+ +GQ RE+E Q R+ E + Q + R+++ + Q+ + RE+
Sbjct: 128 ERETEREGERGRDRQTDGQ-RERERQ-RDAEKERERQTDRERQRQTERNRQKEREREKNR 185
Query: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Q R + + RE+E + ++ + G+ RE+E + + + R+ + + Q RE
Sbjct: 186 QERRERERQREKENKTEDR----HSERGRERERERETETETERKRQTDRERDRQRKTERE 241
Query: 183 QEGQV-REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
+E Q RE+ + + + E+E ++ QK+ E+ +++ Q R + ++ E E
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR--ETER 299
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
+ ++Q E+ +++E +++ E+ RE+E + + + E+ +++ + +++ QT E+ R+
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359
Query: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
+ R Q E+ RE+E RE++ Q ++ E+ +++ +++ + ++++ G++E +
Sbjct: 360 GREGRRQAERERERE---RERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK 416
Query: 362 QKQEEQVRKQE---EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402
Q++ E+ R+ E E+ R++E+Q ++ ++ R+ + Q G Q+++
Sbjct: 417 QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 88.6 bits (218), Expect = 1e-17
Identities = 47/220 (21%), Positives = 122/220 (55%), Gaps = 4/220 (1%)
Query: 210 EQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEE 269
++E QK+ E+ E+ + R+ + + + E+ + ++ ++ ++ R++E + + E
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
+ R++E++ +QKE+ + E+ GE+ Q + RE+E Q ++E+ R+ + + +Q
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRD--RQTDGQRERERQRDAEKERERQTDRERQRQ 170
Query: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ-KQEEQVRKQEEQMRKQEEQMRKQEEQ 388
E+ QKE+ E+ Q ++ E+ E+E + + + E+ R++E + + E RK++
Sbjct: 171 TERN-RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229
Query: 389 MRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
+ ++ E++ + ++E+ E+E + +++E+ R ++
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Score = 82.8 bits (203), Expect = 6e-16
Identities = 60/290 (20%), Positives = 143/290 (49%), Gaps = 17/290 (5%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E +EKN + + E + ++++ + E R+ E ++ + + R+ + + Q
Sbjct: 178 EREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRK 237
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
RE+E Q + RE E + + R+++ R++E RE++ + Q R+
Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKE---RERQTDRKRQRRTERD 294
Query: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
+E + + + + RE+E + + + RE+E RE+E Q + + +E+E + + Q
Sbjct: 295 RETERKRERQRERERERERNRKRERERERE---RERERQRETERDREKERERKRKRQTEM 351
Query: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE----- 241
RE+ Q G + + E+E + + ++ +E + E++ +Q+E+ + E+
Sbjct: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ 411
Query: 242 -QVQKQEEQVQKQE-----EQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
+ +KQ E+ + +E E+ R++E+Q + ++ R+ + Q +Q++++
Sbjct: 412 RETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRS 461
Score = 77.8 bits (190), Expect = 2e-14
Identities = 47/218 (21%), Positives = 113/218 (51%), Gaps = 20/218 (9%)
Query: 237 GEQEEQVQKQEEQVQKQ----EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
G QE ++ Q K + + +Q+E+ R +E++ E+E +++E+ ++++
Sbjct: 32 GSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD--RKRERRREKDRHR 89
Query: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE---QMWK 349
+++ Q ++ +E+E Q + ++ RE+E K+ E+ E++ + ++ Q +
Sbjct: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149
Query: 350 QEEQMGEQEEQMQKQEEQVR-----KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMG 404
+ ++ E+E + Q E+ R +Q+E+ R++ Q R++ E+ R++E + ++ + G
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
Query: 405 EQKEQMREQE------EQMGEQKEQMRKQEEHMGEQKE 436
++E+ RE E Q ++++ RK E +Q E
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAE 247
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 146 bits (369), Expect = 3e-35
Identities = 97/359 (27%), Positives = 216/359 (60%), Gaps = 14/359 (3%)
Query: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
E+E Q R Q V E + GQ RE + Q EQ+ + ++Q + Q+
Sbjct: 54 EEEPQERNSSPQRPAVSAPVGASEIAEETRPGQ-RELQLQQLEQQPEPQQQPQHEQLQQP 112
Query: 130 QVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQEGQVREQEGQVR 188
Q + Q +Q+GQ +Q Q+++++ Q V QE + E Q+ Q+ Q++ Q+ Q +
Sbjct: 113 QPHLELQQQPQQDGQ--QQLSQLQQEKHQSVHHQE---LKPELQLMHQQQQLQPQQVQEQ 167
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ-EEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
++ Q EQ QE+Q+ +Q+EQ+Q+Q +EQ Q++Q + Q++Q+ +Q+EQ+Q+Q
Sbjct: 168 QRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQ- 226
Query: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE 307
Q Q+Q+EQ+++Q++ + Q++ Q +Q L Q++Q + ++Q EQ++ +Q+ +++
Sbjct: 227 -QFQQQQEQLQQQQQLLLLQQQ---GQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQ 282
Query: 308 QEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ 367
QE+ ++Q++Q+ +Q+++ +Q++ E E++ ++ +G ++E Q+++E
Sbjct: 283 QEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQEL 342
Query: 368 VRKQEEQMRKQEEQMR-KQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMR 425
R+QE + ++++ Q++ K +E++++ E+Q+ +Q++Q+ +Q+ Q+ ++G Q+++++
Sbjct: 343 ERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQ 401
Score = 143 bits (361), Expect = 3e-34
Identities = 102/361 (28%), Positives = 222/361 (61%), Gaps = 27/361 (7%)
Query: 56 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 115
E+E Q R Q V E + GQ RE + Q EQ+ + ++Q + Q+
Sbjct: 54 EEEPQERNSSPQRPAVSAPVGASEIAEETRPGQ-RELQLQQLEQQPEPQQQPQHEQLQQP 112
Query: 116 QVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQEGQVREQEGQVR 174
Q + Q +Q+GQ +Q Q+++++ Q V QE + E Q+ Q+ Q++ Q QV+
Sbjct: 113 QPHLELQQQPQQDGQ--QQLSQLQQEKHQSVHHQE---LKPELQLMHQQQQLQPQ--QVQ 165
Query: 175 EQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE 234
EQ+ ++++Q+ Q++ Q+ Q +Q Q EQ +Q ++++ +Q+Q+EQ+ Q++Q+ +Q+E
Sbjct: 166 EQQ-RLQQQQEQLQTQQAQE-QQVLQQQEQLQQQVQEQQLLQQQQEQL--QQQQLLQQQE 221
Query: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEE-QMREQ--EEQMREQEEQMLKQKEQTEQEEQT 291
Q+ Q++Q Q+Q+EQ+Q+Q++ + Q++ Q+++Q ++Q + ++Q+L+Q++ Q++
Sbjct: 222 QL--QQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLL 279
Query: 292 GEQEEQMREQEEQMREQEEQMREQEEQMR------EQEEQMGKQEEQMWEQKEQMWEQKE 345
+Q+EQ+++Q++Q Q++Q + Q++Q++ E+EE++ + + EQ EQ+
Sbjct: 280 LQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQR 339
Query: 346 QMWKQEEQMGEQEEQMQ---KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402
Q ++++++ Q+EQ Q K +E++++ E+Q+ +Q++Q+ +QE Q+ ++G Q+++
Sbjct: 340 QELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQE 399
Query: 403 M 403
+
Sbjct: 400 V 400
Score = 139 bits (351), Expect = 4e-33
Identities = 100/359 (27%), Positives = 215/359 (59%), Gaps = 34/359 (9%)
Query: 98 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 157
E+E Q R Q V E + GQ RE + Q EQ+ + ++Q + Q+
Sbjct: 54 EEEPQERNSSPQRPAVSAPVGASEIAEETRPGQ-RELQLQQLEQQPEPQQQPQHEQLQQP 112
Query: 158 QVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQMGEQEGQMGEQEEQMGEQEEQMQ 216
Q + Q +Q+GQ +Q Q+++++ Q V QE + E Q+ Q++Q+ Q +Q+Q
Sbjct: 113 QPHLELQQQPQQDGQ--QQLSQLQQEKHQSVHHQELK---PELQLMHQQQQL--QPQQVQ 165
Query: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ-EEQMRKQEEQMREQEEQMREQE 275
+Q+ ++ +Q+EQ++ Q+ QE+QV +Q+EQ+Q+Q +EQ Q++Q + Q++Q+ +Q+
Sbjct: 166 EQQ-RLQQQQEQLQTQQ----AQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220
Query: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ--EEQMREQEEQMREQEEQMGKQEEQM 333
EQ+ +Q+ Q +QE+ +Q+ + +Q+ Q+++Q ++Q + ++Q+ EQ +Q Q++ +
Sbjct: 221 EQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQ-QQAQLQQQLL 279
Query: 334 WEQKEQMWEQKEQMWKQEEQMGEQEEQMQ------KQEEQVRKQ--------EEQMRKQE 379
+Q+EQ+ +Q++Q Q++Q Q++Q+Q ++EE+V + E+++ +Q
Sbjct: 280 LQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQR 339
Query: 380 EQMRKQEEQMRKQEEQMGEQK--EQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+++ +Q+E R+QE++ + K E++ + ++Q+ +Q++Q+ +Q+ Q+ +G Q++
Sbjct: 340 QELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQ 398
Score = 135 bits (340), Expect = 7e-32
Identities = 104/387 (26%), Positives = 226/387 (58%), Gaps = 43/387 (11%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
EE +E+N+ Q SEI + +R+L+ ++ E Q + Q Q+++ +
Sbjct: 55 EEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQP 114
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
+ Q Q +Q+GQ +Q Q+++++ Q V QE + E Q+ Q+ Q++
Sbjct: 115 HLELQ--QQPQQDGQ--QQLSQLQQEKHQ------SVHHQE---LKPELQLMHQQQQLQP 161
Query: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Q QV+EQ+ ++++Q+ Q++ Q+ Q E QV +Q+ Q+++Q V+EQ+ +++Q+ Q
Sbjct: 162 Q--QVQEQQ-RLQQQQEQLQTQQAQ----EQQVLQQQEQLQQQ---VQEQQ-LLQQQQEQ 210
Query: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
+++Q Q+ +Q+EQ+ Q++Q Q+Q+EQ+ +Q++Q+ ++Q Q++ +Q+Q
Sbjct: 211 LQQQ---------QLLQQQEQL--QQQQFQQQQEQL-QQQQQLLLLQQQGQLQQQLLQQQ 258
Query: 247 EEQVQKQ---EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEE 303
+ Q+Q+Q ++Q + Q++ + +Q+EQ+++Q++Q L Q +Q+EQ +Q+ Q E
Sbjct: 259 QAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQ----QQQEQLQQQQLQPPPLEP 314
Query: 304 QMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363
+ E+ E + EQE + +QE + ++ E+ EQ++ K +E++ + E+Q+++
Sbjct: 315 EEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQ 374
Query: 364 QEEQVRKQEEQMRKQEEQMRKQEEQMR 390
Q++Q+ +QE Q+ ++ Q+++++
Sbjct: 375 QQQQLEQQEVQLELTPVELGAQQQEVQ 401
Score = 116 bits (290), Expect = 5e-26
Identities = 92/335 (27%), Positives = 194/335 (57%), Gaps = 32/335 (9%)
Query: 8 ELKEKNAELQEELQLVETEKS-EIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E+ E+ Q ELQL + E+ E Q + + + + L Q+ Q Q+ + Q+
Sbjct: 77 EIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQE 136
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
+ + Q + E Q+ Q+ Q++ Q+ Q +++ Q +EQ + QE QV +Q+ Q+++
Sbjct: 137 KHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ 196
Query: 127 Q--EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ- 183
Q E Q+ +Q+ Q + Q+ Q+ +Q+ Q+++Q+ Q ++QE ++Q+ + +Q+GQ+++Q
Sbjct: 197 QVQEQQLLQQQ-QEQLQQQQLLQQQEQLQQQQFQ-QQQEQLQQQQQLLLLQQQGQLQQQL 254
Query: 184 --EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG---- 237
+ Q + Q+ + +Q+ Q+ Q++ + +Q+EQ+Q+Q++Q Q++Q + Q++Q+
Sbjct: 255 LQQQQAQLQQQLLEQQQAQL--QQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPL 312
Query: 238 --EQEEQVQKQ--------EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
E+EE+V+ + E+++++Q +++ +Q+E R+Q EQ + LK +E+ +Q
Sbjct: 313 EPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQ-----EQRQLQLKLQEELQQ 367
Query: 288 EEQTGEQEEQMREQEE---QMREQEEQMREQEEQM 319
EQ EQ++Q EQ+E ++ E ++QE Q+
Sbjct: 368 LEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL 402
Score = 111 bits (278), Expect = 1e-24
Identities = 70/268 (26%), Positives = 162/268 (60%), Gaps = 32/268 (11%)
Query: 195 GEQEGQMGEQEEQMGEQEEQMQK-------------QEEQMGEQEEQMRKQEEQMGEQEE 241
G G ++EE+ E+ Q+ +E + G++E Q+++ E+Q E
Sbjct: 44 GGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQ---PEP 100
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE--QEEQMLKQKEQTEQEEQTGEQEEQMR 299
Q Q Q EQ+Q+ + + Q++ ++ ++Q+ + QE+ ++ + E Q Q++Q++
Sbjct: 101 QQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQ 160
Query: 300 EQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ-KEQMWEQKEQMWKQEEQMGEQE 358
Q+ Q +++ +Q +EQ + + QE+Q+ +Q+EQ+ +Q +EQ Q++Q Q++Q+ +Q+
Sbjct: 161 PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220
Query: 359 EQMQKQEEQVRKQEEQMRKQ------EEQMRKQEEQMRKQEEQMGEQ---KEQMGEQKEQ 409
EQ+Q+Q Q ++Q+EQ+++Q ++Q + Q++ +++Q+ Q+ +Q ++Q Q++
Sbjct: 221 EQLQQQ--QFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQL 278
Query: 410 MREQEEQMGEQKEQ--MRKQEEHMGEQK 435
+ +Q+EQ+ +Q++Q +++Q+E + +Q+
Sbjct: 279 LLQQQEQLQQQQQQQLLQQQQEQLQQQQ 306
Score = 100 bits (249), Expect = 3e-21
Identities = 69/288 (23%), Positives = 183/288 (63%), Gaps = 17/288 (5%)
Query: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63
+ ++ELK + +L + Q ++ ++ + Q +++ + +L+T + QE QV +Q+ Q+++
Sbjct: 141 VHHQELKPE-LQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQA---QEQQVLQQQEQLQQ 196
Query: 64 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 123
Q V+EQ+ +++Q+ Q+++Q Q+ +Q+ Q+++Q+ Q ++QE ++Q+ + +Q+GQ
Sbjct: 197 Q---VQEQQ-LLQQQQEQLQQQ--QLLQQQEQLQQQQFQ-QQQEQLQQQQQLLLLQQQGQ 249
Query: 124 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
+++Q +++Q+ Q+++Q + +Q+ Q+++Q ++++ Q ++Q+ +++Q+ Q+++Q
Sbjct: 250 LQQQ--LLQQQQAQLQQQ--LLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQ 305
Query: 184 EGQVREQEGQMGEQEGQMGEQEEQMG-EQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242
+ Q E + E+E ++ +G EQE + Q+QE + ++ E+ ++Q + + +E+
Sbjct: 306 QLQPPPLEPE-EEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEE 364
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
+Q+ E+Q+++Q++Q+ +QE Q+ ++ Q++++ + + E Q
Sbjct: 365 LQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQ 412
Score = 65.9 bits (159), Expect = 7e-11
Identities = 49/216 (22%), Positives = 128/216 (59%), Gaps = 13/216 (6%)
Query: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDK--IPLPQEGQVREQEGQ 60
++ ++L ++ E ++ QL++ ++ Q ++ + +L+ + + L Q+GQ+++Q
Sbjct: 197 QVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQ--L 254
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+++Q+ Q+++Q + +Q+ Q+++Q ++++ Q ++Q+ +++Q+ Q+++Q+ Q
Sbjct: 255 LQQQQAQLQQQ--LLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPL 312
Query: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
E E+E +V + V Q EQ+ Q E++ +E E Q +++ Q++ QE ++
Sbjct: 313 E---PEEEEEVELELMPVDLGSEQELEQQRQELERQ---QELERQQEQRQLQLKLQE-EL 365
Query: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ 216
++ E Q+ +Q+ Q+ +QE Q+ ++G Q++++Q
Sbjct: 366 QQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQ 401
Score = 65.5 bits (158), Expect = 9e-11
Identities = 49/191 (25%), Positives = 99/191 (51%), Gaps = 30/191 (15%)
Query: 274 QEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE------------ 321
QEE+ +++ + Q EE Q E +Q EQ E
Sbjct: 52 QEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQ 111
Query: 322 ---------QEEQMGKQE-EQMWEQKEQMWEQKE-----QMWKQEEQMGEQEEQMQKQEE 366
Q +Q G+Q+ Q+ ++K Q +E Q+ Q++Q+ Q+ Q Q++ +
Sbjct: 112 PQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQ 171
Query: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQ-EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMR 425
Q ++Q + + QE+Q+ +Q+EQ+++Q +EQ Q++Q Q++Q+ +Q+EQ+ Q++Q +
Sbjct: 172 QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQL--QQQQFQ 229
Query: 426 KQEEHMGEQKE 436
+Q+E + +Q++
Sbjct: 230 QQQEQLQQQQQ 240
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 137 bits (346), Expect = 1e-32
Identities = 101/420 (24%), Positives = 227/420 (54%), Gaps = 23/420 (5%)
Query: 9 LKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQV 68
++EK E QEE ++ + +I + + + E + ++ E++ + E E
Sbjct: 212 VEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERAR 271
Query: 69 REQEGQVR---EQEGQVREQEGQVR-EQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
E E + R EQ+ ++ ++ ++ E++ +E+E + E+ ++RE+E + E+ ++
Sbjct: 272 LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331
Query: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
+E+E + E+ +++E+E + E+ +++E+E + E+ + R +E E++ +V EQ+
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE----EEKAKVEEQK 387
Query: 185 GQVREQEGQMGEQEGQM-GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
+ +E + QE ++ GE+ EQ E + +K+ ++ Q ++KQ E+ G + V
Sbjct: 388 RNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK---V 444
Query: 244 QKQEEQVQKQEEQMRKQE---EQMREQEEQMREQEEQMLKQKEQTEQEEQTGE-QEEQMR 299
Q + E++Q+ + +K+E E++++ +E E + M ++K TE + Q GE +++
Sbjct: 445 QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 504
Query: 300 EQEEQM-REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358
E R + +E + + GK+ E++ ++ + ++ + KQ++Q E
Sbjct: 505 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALE 564
Query: 359 -EQMQKQEEQVRK---QEEQMRKQEEQMRK--QEEQMRKQEEQMGEQKEQMGEQKEQMRE 412
E+++K+ E+ RK +EEQ RKQEE RK +EE+ R+ +E++ ++ + E++++M E
Sbjct: 565 LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Score = 134 bits (338), Expect = 1e-31
Identities = 99/431 (22%), Positives = 222/431 (51%), Gaps = 36/431 (8%)
Query: 35 KELKRKLETDKIPLPQEGQVREQEGQVREQEG-QVREQEGQVREQEGQVREQ-----EGQ 88
K + +LE ++I + E+ + R + Q R ++ Q E GQV +Q +
Sbjct: 14 KREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNS 73
Query: 89 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV---------- 138
V ++E + QV + + RE+ Q R QE R++E
Sbjct: 74 VPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLP 133
Query: 139 -REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE------QEGQVREQEGQVREQE 191
R + E E +E++ + R++ ++ E E + ++ + ++E + +E+E
Sbjct: 134 SRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEE 193
Query: 192 GQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE--- 248
+ + G +GE + ++ +E+ + QEE + + + E+ ++EE+ Q +E
Sbjct: 194 EEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISH 253
Query: 249 -QVQKQEEQMRKQEEQMR-EQEEQMR---EQEEQMLKQKEQTEQEEQTGEQEEQMREQE- 302
+ ++E++ R + E+ R E EE+ R EQ++++ ++ + E EE+ QE + RE E
Sbjct: 254 HEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEE 313
Query: 303 -EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
E+MRE+E++ E+ ++++E+E++ ++ +++ E++++ E+++++ ++E++ E+ ++
Sbjct: 314 RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRA 373
Query: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
+ +EE+ K EEQ R ++ + +K Q K + + EQK + G+ + + QE+++ Q
Sbjct: 374 RAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE-GKWVNEKKAQEDKL--QT 430
Query: 422 EQMRKQEEHMG 432
++KQ E G
Sbjct: 431 AVLKKQGEEKG 441
Score = 127 bits (318), Expect = 3e-29
Identities = 105/477 (22%), Positives = 246/477 (51%), Gaps = 52/477 (10%)
Query: 8 ELKEKNAELQEELQLVETEK----------SEIQLHIKELKRKLETDKIPLPQEGQVREQ 57
E +EK+ QE ++ ETE + + + KE K K E ++ P+ G + E
Sbjct: 148 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEE-EKPKRGSIGEN 206
Query: 58 EGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQ 113
+ +V +E QE V + GQ+ +E + E+ Q ++ + E+E + R +
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266
Query: 114 EGQVR----EQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQVREQEGQVREQEGQVRE 168
+ R E+E EQ+ ++ ++ ++ E++ +E+E + E+ ++RE+E + E
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE 326
Query: 169 QEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQ 228
+ +++E+E + E+ +++E+E + E+ ++ E+E++ E+ ++ + +EE+ + EEQ
Sbjct: 327 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Query: 229 MRKQ--EEQMGEQEEQVQKQEEQVQKQE----EQMRKQEEQMREQ--EEQMREQEEQMLK 280
R + EE+ +E K E+ QK E + + QE++++ ++Q E+ ++
Sbjct: 387 KRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQA 446
Query: 281 QKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR---EQEEQMREQEEQMGKQEEQMWEQK 337
++E+ ++++ T ++EE E+ ++ +E +E+++ ++++ E + Q G+ +
Sbjct: 447 KREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHT 506
Query: 338 EQMWEQ---------KEQMWKQEEQMGEQEEQMQKQ---------EEQVRKQEEQMRKQE 379
E + + KE + + G++ E+++++ E+ +KQ+E + E
Sbjct: 507 ENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELE 566
Query: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
E +K+EE+ + EE+ EQ+ + E ++RE+EE+ KE++ ++ E+++
Sbjct: 567 ELKKKREERRKVLEEE--EQRRKQEEADRKLREEEEKR-RLKEEIERRRAEAAEKRQ 620
Score = 124 bits (312), Expect = 1e-28
Identities = 92/469 (19%), Positives = 233/469 (49%), Gaps = 42/469 (8%)
Query: 2 PRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61
P IT+ L + +Q + ET + E + ++ + ++E + + ++ +
Sbjct: 123 PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEE 182
Query: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV--REQEGQVREQEGQVRE 119
++E + +E+E + + + G + E + +V +E QE V + GQ+ +E + E
Sbjct: 183 NKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEE 242
Query: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-EQEG 178
+ Q ++ + E + +E+ + + E+E EQ+ ++ ++ ++ E++
Sbjct: 243 EREQGSDEISHHEKMEEEDKER-AEAERARLEAEERERIKAEQDKKIADERARIEAEEKA 301
Query: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
+E+E + E+ +M E+E + E+ +++ E+E++ ++ +++ E+E++ ++ +++ E
Sbjct: 302 AAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKE 361
Query: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQ--EEQMREQEEQMLK--------------QK 282
+E++ ++ ++ + +EE+ K EEQ R + EE+ +E +K +K
Sbjct: 362 EEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEK 421
Query: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE--EQMGKQEEQMWEQKEQM 340
+ E + QT ++Q E+ +++ + E+++E + +++E ++ K++++ E+ +
Sbjct: 422 KAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSF 481
Query: 341 WEQKEQMWKQEEQMGEQEEQMQKQEE----------QVRKQEEQMRKQEEQMRKQEEQMR 390
++K+ + + Q GE K E V +E + Q E ++ EE R
Sbjct: 482 MDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR 541
Query: 391 KQEEQMGEQKEQMGEQKEQ----------MREQEEQMGEQKEQMRKQEE 429
++ E E+ E++ +++++ RE+ ++ E++EQ RKQEE
Sbjct: 542 RRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE 590
Score = 120 bits (301), Expect = 2e-27
Identities = 111/469 (23%), Positives = 233/469 (49%), Gaps = 45/469 (9%)
Query: 3 RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61
R E L++K E E L Q+ + + Q + + + K T + + + E
Sbjct: 44 RARQERLRQKQEE--ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLA 101
Query: 62 REQEG-QVREQEGQVREQEGQVREQEGQV----REQEGQVREQEGQVREQEGQVREQEGQ 116
R +E Q R QE R++E + + R + E E +E++ + R++ +
Sbjct: 102 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 161
Query: 117 VREQEGQVRE------QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 170
+ E E + ++ + ++E + +E+E + + + G + E + +V +E QE
Sbjct: 162 IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQE 221
Query: 171 GQV--REQEGQVREQEGQVREQEGQMGEQE----GQMGEQEEQMGEQEEQMQKQEEQMGE 224
V + GQ+ +E + +E+E + G E +M E++++ E E + EE+
Sbjct: 222 ETVVMSLKNGQISSEEPK-QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERI 280
Query: 225 QEEQMRKQEEQMG--EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
+ EQ +K ++ E EE+ QE + ++ EE+ R +EE+ R EE+ R +EE+ +
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAE 340
Query: 283 EQT---EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ---MREQE--EQMGKQEEQMW 334
E+ E+E++ E+ ++++E+E++ E+ ++ R +EE+ + EQ+ +Q+ +++ M
Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQ 400
Query: 335 EQK---EQMWEQKEQMWKQEEQMGEQEEQ---MQKQEEQ----VRKQEEQMRKQEEQMRK 384
E K E++ ++ E W E++ E + Q ++KQ E+ V+ + E++++ + +K
Sbjct: 401 ETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKK 460
Query: 385 QE---EQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
+E E+++K +E E K M ++K+ E + Q GE K E+
Sbjct: 461 EEIKDEKIKKDKEPKEEVKSFM-DRKKGFTEVKSQNGEFMTHKLKHTEN 508
Score = 119 bits (297), Expect = 7e-27
Identities = 92/419 (21%), Positives = 209/419 (49%), Gaps = 44/419 (10%)
Query: 55 REQEGQVREQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQ-----E 107
R++ ++R + ++ Q E+E + R + Q R ++ Q E GQV +Q +
Sbjct: 12 RQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQ 71
Query: 108 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV- 166
V ++E + QV + + RE+ Q R QE R++E + +
Sbjct: 72 NSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLS 131
Query: 167 ---REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG 223
R + E E +E++ + R++ ++ E E ++ E+ +K++++
Sbjct: 132 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 191
Query: 224 EQEEQMRKQ------EEQMGEQEEQVQKQEEQV-------------QKQEEQMRKQEEQM 264
E+EE+ K+ + ++ +E+ + QEE V KQEE+ + +++
Sbjct: 192 EEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEI 251
Query: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR---------EQEEQMREQEEQMREQ 315
E+ E +E+ ++ + E EE+ + EQ + E EE+ QE + RE
Sbjct: 252 SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREA 311
Query: 316 E--EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373
E E+MRE+E++ ++ +++ E++++ E+++++ ++E++ E+ ++++++E++ ++ +
Sbjct: 312 EERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 371
Query: 374 QMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQM-GEQKEQMRKQEEHM 431
+ R +EE+ K EEQ K+ +Q+ E+K M E K + + E+++ G+ + + QE+ +
Sbjct: 372 RARAEEEEKAKVEEQ--KRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKL 428
Score = 112 bits (281), Expect = 5e-25
Identities = 80/377 (21%), Positives = 192/377 (50%), Gaps = 20/377 (5%)
Query: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
E+ ++R Q+ + E + + ++E RE+ + R++ + +++E E G
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEE----ESLG 60
Query: 130 QVREQ-----EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
QV +Q + V ++E + QV + + RE+ Q R QE R++E
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Query: 185 GQ--VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG-EQEEQMRKQEEQMGEQEE 241
+ + + + Q E + E+EE+ + ++E+ E+ E + K ++ ++
Sbjct: 121 FDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDA 180
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
+ K+E++ +++EE+ + + + E + ++ +E+ Q+E + G+ + +Q
Sbjct: 181 EENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQ 240
Query: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE--QKEQMWEQKEQMWKQEEQMGEQEE 359
EE+ REQ E+M E++++ + E E ++E++ ++++ E E EE
Sbjct: 241 EEE-REQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEE 299
Query: 360 QMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGE 419
+ QE + R+ EE+ R +EE+ R EE+ R +EE+ ++ E++++++E+E++ E
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEE-----KRAAEERQRIKEEEKRAAE 354
Query: 420 QKEQMRKQEEHMGEQKE 436
++++++++E+ E+++
Sbjct: 355 ERQRIKEEEKRAAEERQ 371
Score = 102 bits (255), Expect = 5e-22
Identities = 80/363 (22%), Positives = 191/363 (52%), Gaps = 38/363 (10%)
Query: 7 EELKEKNAELQEELQLVETE--KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ--VR 62
EE KE+ + L+ E E K+E I + + ++E ++ QE + RE E + +R
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR 318
Query: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122
E+E + E+ +++E+E + E+ +++E+E + E+ +++E+E + E+ + R +E
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378
Query: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQ-VREQEGQVREQEGQVREQEGQ 179
+ + E Q R ++ + ++ Q + +G+ EQ EG+ V E++ Q + + V +++G+
Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGE 438
Query: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE- 238
+ + Q + ++ Q + + E +++ +++++ +++ + ++++ + + Q GE
Sbjct: 439 EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEF 498
Query: 239 -----------------------QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE 275
+E + Q E ++ EE R++ E E+ E++++++
Sbjct: 499 MTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ 558
Query: 276 EQMLKQ----KEQTEQEEQTGEQEEQMREQEE---QMREQEEQMREQEEQMREQEEQMGK 328
++ + K++ E+ + E+EEQ R+QEE ++RE+EE+ R +EE R + E K
Sbjct: 559 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEK 618
Query: 329 QEE 331
+++
Sbjct: 619 RQK 621
Score = 61.2 bits (147), Expect = 2e-09
Identities = 51/266 (19%), Positives = 114/266 (42%), Gaps = 43/266 (16%)
Query: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQ-----EEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
+ +++ E ++ E+MR + E++ Q EE+ ++ + +QE +KQEE+ Q
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 268 ---------EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE- 317
+ + ++E + Q E +++ E R +E + + +E + Q+E
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 318 ---------------QMREQEEQMGKQEEQMWEQKEQMWEQKE----------QMWKQEE 352
+ E ++E+ E +++ +E +E W+ E
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181
Query: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ--MGEQKEQMGEQKEQM 410
+ +++++ +++EE+ K+ Q E M +E+ QEE M + Q+ ++ +
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQVEVM-VEEKTTESQEETVVMSLKNGQISSEEPKQ 240
Query: 411 REQEEQMGEQKEQMRKQEEHMGEQKE 436
E+ EQ ++ K EE E+ E
Sbjct: 241 EEEREQGSDEISHHEKMEEEDKERAE 266
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 136 bits (342), Expect = 4e-32
Identities = 90/420 (21%), Positives = 223/420 (53%), Gaps = 41/420 (9%)
Query: 35 KELKRKLETDKIPLPQEGQ----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 90
+EL LE+ + + Q + +++Q+ QV Q + ++ ++ + + + E +
Sbjct: 72 QELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILT 131
Query: 91 EQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 146
++ ++ + R E + ++ G+++ +++E E + Q +E++
Sbjct: 132 LEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSS 191
Query: 147 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQMGEQEGQMGEQE 205
+E ++ Q ++ + QV E QV+ E++ + +G+ + +M +
Sbjct: 192 CREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMS 251
Query: 206 EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE-----------EQVQKQEEQVQKQE 254
+ +E+ ++ ++ E E + + + QM E EQ+Q + + ++++
Sbjct: 252 VEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEV 311
Query: 255 EQM------------------RKQEEQMREQEEQMREQEEQMLKQKEQ-TEQEEQTGEQE 295
E + ++Q+++++EQEE +REQE Q ++++E+ EQ E+ EQ+
Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371
Query: 296 EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
+ ++EQ E++R+QE+++R+QEE++R++EE++ KQE+++W+Q+E++W+++E++ KQEE++
Sbjct: 372 KTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLA 431
Query: 356 -EQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK-EQMGEQKEQMREQ 413
Q ++ KQ + + E + +++ + E+Q+++ +E++ E+ E Q +Q+ Q
Sbjct: 432 LSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQ 491
Score = 129 bits (324), Expect = 5e-30
Identities = 96/437 (21%), Positives = 227/437 (51%), Gaps = 17/437 (3%)
Query: 2 PRITNEELKEKNAELQEELQLVETEKSE-IQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
P + E + K A +++L+ + KS I K K+K TD P G
Sbjct: 11 PMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKK--TDSSPETTTSGGCHSPGD 68
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+ QE V + V Q+ E +++Q+ QV Q + ++ ++ + + + E
Sbjct: 69 SQYQELAVALESSSVTIS--QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLET 126
Query: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 176
+ ++ ++ + R E + ++ G+++ +++E E + Q +E+
Sbjct: 127 INILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEE 186
Query: 177 EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ-EEQ 235
+ +E ++ Q ++ + Q+ E +Q+Q + ++ + + R + +E+
Sbjct: 187 DRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQER 246
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE 295
M + + + +E+ ++ ++++ E + E + QM E L T EQ ++
Sbjct: 247 MWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS--LAPPAVTSVVEQLQDEA 304
Query: 296 EQMREQEEQMREQEEQMREQEEQM----REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
+ +R++ E + + + E + + +EQ++++ +QEE + EQ+ Q ++E++ +Q
Sbjct: 305 KHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQN 364
Query: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
E++ EQ++ +Q+Q E++RKQE+++RKQEE++RK+EE+++KQE+++ +Q+E++ +++E+++
Sbjct: 365 ERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQ 424
Query: 412 EQEEQMG-EQKEQMRKQ 427
+QEE++ Q ++ KQ
Sbjct: 425 KQEERLALSQNHKLDKQ 441
Score = 118 bits (295), Expect = 1e-26
Identities = 78/344 (22%), Positives = 185/344 (53%), Gaps = 21/344 (6%)
Query: 109 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR----EQEG 164
Q+ E +++Q+ QV Q + ++ ++ + + + E + ++ ++ +
Sbjct: 87 QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKR 146
Query: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE 224
R E + ++ G+++ +++E E + Q E++ +E +Q+ +Q +
Sbjct: 147 AARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIK 206
Query: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQK--QEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
+ + Q+ E +QVQ + ++ K + E+ R QE + E +EE+
Sbjct: 207 ERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIH 266
Query: 283 EQTEQEEQTGEQEEQMREQEE----QMREQEEQMREQEEQMREQEEQM-GKQEEQMW--- 334
E E E + QM E + EQ++++ + +R++ E + GK + Q+
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326
Query: 335 -------EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
EQK+++ EQ+E + +QE Q ++E++ +Q E++R+Q++ +++Q E++RKQE+
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQ 386
Query: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
++RKQEE++ +++E++ +Q++++ +QEE++ +++E+++KQEE +
Sbjct: 387 RLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430
Score = 116 bits (290), Expect = 5e-26
Identities = 98/419 (23%), Positives = 209/419 (49%), Gaps = 30/419 (7%)
Query: 12 KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQ 71
+ A LQ LQ E++ + H+ ++ L+ ++ L ++ + +G+ + ++ +
Sbjct: 193 REAVLQRWLQQTIKERALLNAHVTQVTESLK--QVQLERDEYAKHIKGERARWQERMWKM 250
Query: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQ 130
+ R + + + +++E E + E + Q+ E V EQ + + + +
Sbjct: 251 SVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQE 310
Query: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190
V EG+++ Q + +EQ+ +++EQE +REQE Q +VREQE ++ EQ
Sbjct: 311 VEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQ------RVREQE-RLCEQ 363
Query: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
++ EQ+ + EQ E++ +QE++++KQEE++ ++EE+++KQE+++ +QEE++ K+EE++
Sbjct: 364 NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERL 423
Query: 251 QKQEE-----QMRKQEEQMREQEEQMRE--QEEQMLKQKEQTEQEEQTGEQEEQMREQEE 303
QKQEE Q K ++Q+ E + + E++ Q EQ +E Q EE +
Sbjct: 424 QKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASH 483
Query: 304 QMREQEEQMR--------EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
Q ++ E Q+ + + + +EE+ + + E E E ++
Sbjct: 484 QNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESR-EATSSFMDLPKEKA 542
Query: 356 EQEEQMQKQE---EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
+ EQ++++E Q + MR+ Q + ++M E ++ +++E+M+
Sbjct: 543 DGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMK 600
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 135 bits (339), Expect = 1e-31
Identities = 77/251 (30%), Positives = 165/251 (65%), Gaps = 13/251 (5%)
Query: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMG----EQEEQMQKQEEQMGEQEEQMRKQEE 234
Q++++ +R++ +G Q E + + QEE++++QEE++ EQEE++ +QEE
Sbjct: 161 QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEE 220
Query: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ-TEQEEQTGE 293
++ EQEE++ +QEE++++QEE++R+QEE++ EQEE++ EQEE++ +Q+E+ EQE+ G
Sbjct: 221 RLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPG- 279
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE-- 351
+E++ E+ E++ EQE + +E++E++ E+E + + EE + ++E++ +Q E++W+QE
Sbjct: 280 -QERLLEEVEKLLEQERR-QEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETL 335
Query: 352 -EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQM 410
E +E + ++ E++R+ E + E + +Q + R E++ + + + ++Q+
Sbjct: 336 RELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQV 395
Query: 411 REQEEQMGEQK 421
+E E+ G ++
Sbjct: 396 KELEKSGGAEE 406
Score = 131 bits (330), Expect = 1e-30
Identities = 78/230 (33%), Positives = 151/230 (65%), Gaps = 16/230 (6%)
Query: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV----QKQEEQMRKQEEQMREQEEQMREQE 275
EQ+ ++ +RK+ E +G Q + + + + ++QEE++R+QEE++ EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE 219
Query: 276 EQMLKQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE---- 330
E++ +Q+E+ EQEE+ EQEE++REQEE++ EQEE++ EQEE++ EQEE++ +QE
Sbjct: 220 ERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPG 279
Query: 331 -EQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE--- 386
E++ E+ E++ EQ E+ +++E++ E+E + + EE + ++E++R+Q+E++ +QE
Sbjct: 280 QERLLEEVEKLLEQ-ERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLR 336
Query: 387 EQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
E R +E + + E++ E + + E + EQ+ + R E + + +
Sbjct: 337 ELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENK 386
Score = 127 bits (320), Expect = 2e-29
Identities = 82/262 (31%), Positives = 166/262 (63%), Gaps = 28/262 (10%)
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQM----QKQEEQMGEQEEQMRKQEEQMGEQEE 241
Q++++ + ++ +G Q + E + + ++QEE++ EQEE++ +QEE++ EQEE
Sbjct: 161 QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEE 220
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
++ +QEE++ +QEE++R+QEE++REQEE++ EQEE++ EQEE+ EQEE++ EQ
Sbjct: 221 RLCEQEERLCEQEERLREQEERLREQEERLHEQEERLC------EQEERLCEQEERLCEQ 274
Query: 302 E-----EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE 356
E E++ E+ E++ EQE R QEEQ E++ E +E++ ++ E++ +Q E++ +
Sbjct: 275 EKLPGQERLLEEVEKLLEQE---RRQEEQ-----ERLLE-RERLLDEVEELLEQ-ERLRQ 324
Query: 357 QEEQMQKQE---EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ 413
Q+E++ +QE E R +E + ++ E++R+ E + E + EQ+ + E++ +
Sbjct: 325 QDERLWQQETLRELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNE 384
Query: 414 EEQMGEQKEQMRKQEEHMGEQK 435
+ + ++Q+++ E+ G ++
Sbjct: 385 NKSTLQLEQQVKELEKSGGAEE 406
Score = 120 bits (300), Expect = 3e-27
Identities = 84/256 (32%), Positives = 150/256 (58%), Gaps = 12/256 (4%)
Query: 109 QVREQEGQVREQEGQVREQEGQVREQEGQV-----REQEGQVREQEGQVREQEGQVREQE 163
Q++++ +R++ V Q Q + Q+ R QE ++REQE ++ EQE ++ EQE
Sbjct: 161 QLQDETNHLRKELESVGRQL-QAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE 219
Query: 164 GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG 223
++ EQE ++ EQE ++REQE ++REQE ++ EQE ++ EQEE++ EQEE++ +QE+ G
Sbjct: 220 ERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPG 279
Query: 224 EQE--EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQ 281
++ E++ K EQ QEEQ + E + E + ++E++R+Q+E++ +QE L++
Sbjct: 280 QERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQE--TLRE 337
Query: 282 KEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
E+ + E+ E E++RE E + E + EQ + R E++ E + Q EQ
Sbjct: 338 LERLRELERLREL-ERLRELERMLELGWEALYEQRAEPRSGFEEL-NNENKSTLQLEQQV 395
Query: 342 EQKEQMWKQEEQMGEQ 357
++ E+ EE G +
Sbjct: 396 KELEKSGGAEEPRGSE 411
Score = 113 bits (282), Expect = 4e-25
Identities = 88/304 (28%), Positives = 174/304 (57%), Gaps = 23/304 (7%)
Query: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
N ++ E + E+ LV+ ++ + +LK + P P G + + Q++++
Sbjct: 113 NSLVRTSKEEKKHEIHLVQ----KLGRSLFKLKNQTAEPLAPEPPAGPSKVE--QLQDET 166
Query: 66 GQVREQEGQVREQEGQVREQEGQV-----REQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+R++ V Q Q + Q+ R QE ++REQE ++ EQE ++ EQE ++ EQ
Sbjct: 167 NHLRKELESVGRQL-QAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQ 225
Query: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
E ++ EQE ++REQE ++REQE ++ EQE ++ EQE ++ EQE ++ EQE ++ QE +
Sbjct: 226 EERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQE-KLPGQERLL 284
Query: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGE-----QEEQMQKQEEQMGEQE---EQMRKQ 232
E E ++ EQE + EQE ++ E+E + E ++E++++Q+E++ +QE E R +
Sbjct: 285 EEVE-KLLEQERRQEEQE-RLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLR 342
Query: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
E + + E++++ E ++ E + +Q + R E++ + + L+ ++Q ++ E++G
Sbjct: 343 ELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSG 402
Query: 293 EQEE 296
EE
Sbjct: 403 GAEE 406
Score = 100 bits (248), Expect = 3e-21
Identities = 53/179 (29%), Positives = 113/179 (63%), Gaps = 12/179 (6%)
Query: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316
+R +E+ + + +++ + K K QT E + + + EQ++++
Sbjct: 116 VRTSKEEKKHEIHLVQKLGRSLFKLKNQTA---------EPLAPEPPAGPSKVEQLQDET 166
Query: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376
+R++ E +G+Q + E + + +QEE++ EQEE++ +QEE++ +QEE++
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNR---RQEERLREQEERLHEQEERLHEQEERLC 223
Query: 377 KQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
+QEE++ +QEE++R+QEE++ EQ+E++ EQ+E++ EQEE++ EQ+E++ +QE+ G+++
Sbjct: 224 EQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQER 282
Score = 92.0 bits (227), Expect = 9e-19
Identities = 84/274 (30%), Positives = 158/274 (57%), Gaps = 24/274 (8%)
Query: 7 EELKEKNAELQEELQLV------ETEKSEIQ--LHIKELKRKLETDKIPLPQEGQVREQE 58
E+L+++ L++EL+ V E E +++ L+ ++ +R E ++ QE ++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE 219
Query: 59 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 118
++ EQE ++ EQE ++REQE ++REQE ++ EQE ++ EQE ++ EQE ++ EQE ++
Sbjct: 220 ERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQE-KLP 278
Query: 119 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178
QE + E E ++ EQE + EQE ++ E+E + E E ++ EQE ++R+Q+ ++ +QE
Sbjct: 279 GQERLLEEVE-KLLEQERRQEEQE-RLLERERLLDEVE-ELLEQE-RLRQQDERLWQQE- 333
Query: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
+RE E ++RE E + E++ E E ++ E + EQ + R E++
Sbjct: 334 TLRELE-RLRELERL---------RELERLRELERMLELGWEALYEQRAEPRSGFEELNN 383
Query: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272
+ + + E+QV++ E+ +E + E R
Sbjct: 384 ENKSTLQLEQQVKELEKSGGAEEPRGSESAAAAR 417
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 131 bits (329), Expect = 1e-30
Identities = 102/346 (29%), Positives = 178/346 (51%), Gaps = 51/346 (14%)
Query: 94 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 153
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 714 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 771
Query: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
++ E+E R+QE +R Q REQE +R
Sbjct: 772 KRR---EEEELARRKQEEALRRQ----REQEIALRR------------------------ 800
Query: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE 273
Q++EE+ +QEE +R+ EE+ E+EE+ +KQEE ++KQEE+ K RE+EE R
Sbjct: 801 --QREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAK---WAREEEEAQRR 854
Query: 274 QEEQMLKQKEQT----EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
EE L+ +E+ +EE+ +E +++ Q+E MR++++Q QE R Q++Q +Q
Sbjct: 855 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQ 911
Query: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ--EEQMRKQEEQMRKQEE 387
QM W Q+ + Q ++QK EE+ +Q EEQ R+Q E M+ ++
Sbjct: 912 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 971
Query: 388 QMRKQEEQM---GEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Q ++Q++++ G + G K + Q+E+ + ++Q ++Q++H
Sbjct: 972 QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQH 1017
Score = 128 bits (322), Expect = 9e-30
Identities = 102/410 (24%), Positives = 210/410 (51%), Gaps = 45/410 (10%)
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
G + + G+V G +QE R+QE Q ++ Q+ +++Q QV
Sbjct: 575 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVL 634
Query: 126 EQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Q+ + +Q+ Q+ Q + + ++ +Q G + E + +
Sbjct: 635 AQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQ 694
Query: 183 ----QEGQVRE---QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
+ G V + G Q+ + E+ + EQ +++ E ++EE+ RK++E+
Sbjct: 695 PTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE 754
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQM--REQEEQMREQEEQMLKQKEQTEQEEQTGE 293
+ Q+E++ ++ Q++EE+ R++EE++ R+QEE +R Q EQ + + Q E+EE+ +
Sbjct: 755 LRRQQEEILRR----QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-Q 809
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
QEE +R EE+ RE+EE+ R+QEE +R+QEE+ K + E + ++ E + +M ++ +
Sbjct: 810 QEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 868
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQM----RKQEEQMRKQEEQM--------GEQKE 401
+ +EE+ +++E +V++Q+E MR++++Q R Q++Q ++Q QM G+Q
Sbjct: 869 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 928
Query: 402 ---------------QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Q E++ + + +EEQ +Q+E M+ ++ +Q++
Sbjct: 929 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 978
Score = 119 bits (299), Expect = 4e-27
Identities = 93/315 (29%), Positives = 162/315 (51%), Gaps = 51/315 (16%)
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 714 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 771
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
++ E+E +QEE + Q EQ Q++EE+ +QEE +R+ EE+ E+EE+
Sbjct: 772 KRRE---EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER- 827
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMR 299
+KQEE ++KQEE+ K RE+EE R EE L+ +E+ +EE+ +E +++
Sbjct: 828 RKQEELLRKQEEEAAKWA---REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
Query: 300 EQEEQMREQEEQM----REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQEEQ 353
Q+E MR++++Q R Q++Q ++Q QM W Q+ + Q + E Q
Sbjct: 885 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 944
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE-------------------------- 387
E+E + Q +EEQ R+Q E M+ ++Q ++Q++
Sbjct: 945 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1004
Query: 388 -QMRKQEEQMGEQKE 401
QM+KQ++Q + ++
Sbjct: 1005 RQMQKQQQQQQQHQQ 1019
Score = 108 bits (269), Expect = 1e-23
Identities = 88/317 (27%), Positives = 166/317 (52%), Gaps = 20/317 (6%)
Query: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 714 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 771
Query: 112 ----EQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQ 165
E+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E +
Sbjct: 772 KRREEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER 827
Query: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
R+QE +R+QE + + + E + ++ E +M E+ ++ +EE+ +++E ++ Q
Sbjct: 828 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886
Query: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQK 282
+E MR++++Q QE + Q++Q Q+Q QM+ Q+ + Q L +
Sbjct: 887 KELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 943
Query: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
++ E+E + +EEQ R+Q E M+ ++Q ++Q++++ + K E E
Sbjct: 944 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-SGWGNVSKPSGTTKSLLEIQQE 1002
Query: 343 QKEQMWKQEEQMGEQEE 359
+ QM KQ++Q + ++
Sbjct: 1003 EARQMQKQQQQQQQHQQ 1019
Score = 103 bits (258), Expect = 2e-22
Identities = 82/314 (26%), Positives = 166/314 (52%), Gaps = 17/314 (5%)
Query: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR----E 70
E ++L+ + K E + E++ K E ++ +E + R+QE +R Q+ + R E
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREE 776
Query: 71 QEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQE 128
+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E + R+QE
Sbjct: 777 EELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQE 831
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
+R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+ Q+ +R
Sbjct: 832 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
+++ Q QE Q++Q +Q QM+ Q+ + Q ++QK EE
Sbjct: 892 QRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 948
Query: 249 QVQKQ--EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
+ ++Q EEQ R+Q E M+ ++Q ++Q++++ ++ T E +E+ QM+
Sbjct: 949 ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1008
Query: 307 EQEEQMREQEEQMR 320
+Q++Q ++ ++ R
Sbjct: 1009 KQQQQQQQHQQPNR 1022
Score = 92.4 bits (228), Expect = 7e-19
Identities = 75/284 (26%), Positives = 147/284 (51%), Gaps = 12/284 (4%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
+E+ + QEEL+ + E Q +E KR+ E + QE +R Q REQE +R
Sbjct: 745 EEEERKRQEELRRQQEEILRRQQE-EERKRREEEELARRKQEEALRRQ----REQEIALR 799
Query: 70 EQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
Q E + ++QE +R E + RE+E + R+QE +R+QE + + + E + ++ E
Sbjct: 800 RQREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEEN 858
Query: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
++ E+ ++R +E + + +E +V+ Q+ +R+++ ++QE R Q+ Q ++Q Q+
Sbjct: 859 RLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ---QQQEALRRLQQQQQQQQLAQM 915
Query: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ-EEQMRKQEEQMGEQEEQVQKQ 246
+ Q+ + Q ++QK EE+ Q E+ R+Q+ ++ + +Q Q+Q
Sbjct: 916 KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQ 975
Query: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
++Q + K + E +E+ QM KQ++Q +Q +Q
Sbjct: 976 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019
Score = 77.4 bits (189), Expect = 2e-14
Identities = 83/454 (18%), Positives = 202/454 (44%), Gaps = 39/454 (8%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKE----LKRKLETDKIPLPQEGQVREQEGQVREQE 65
+E+ + +EE +L ++ E +E L+R+ E ++ QE +R E + RE+E
Sbjct: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-QQEEALRRLEERRREEE 825
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
+ R+QE +R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+
Sbjct: 826 ER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Q+ +R+++ ++QE R Q+ Q ++Q Q++ Q+ + Q
Sbjct: 885 RQKELMRQRQ---QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR---KQEEQMGEQEEQ 242
++++ E E+E Q+ +EEQ +Q E M+ ++Q +Q++++ + G +
Sbjct: 942 EIQKLE---EERERQL--REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 996
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK--EQTEQEEQTGEQEEQMRE 300
++ Q+E+ ++ ++Q +Q++Q +Q + R L TG + +
Sbjct: 997 LEIQQEEARQMQKQ--QQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASD 1054
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
+ + + +++G + + + + ++ + E+EE+
Sbjct: 1055 LVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEK 1114
Query: 361 MQKQEEQVRKQEEQMRKQEEQM------------------RKQEEQMRKQEEQMGEQKEQ 402
+ K + V K ++ + EQM K+ E + + +
Sbjct: 1115 LLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1174
Query: 403 MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
E KE ++ E+ +QK ++Q++ + +Q++
Sbjct: 1175 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQ 1208
Score = 60.8 bits (146), Expect = 2e-09
Identities = 78/478 (16%), Positives = 196/478 (41%), Gaps = 89/478 (18%)
Query: 3 RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQ 60
R+ +E+ QEEL + E E ++ +E +R+LE +++ + +E ++R +E +
Sbjct: 816 RLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 875
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+ +E +V+ Q+ +R+++ Q QE R Q+ Q ++Q Q++ Q+
Sbjct: 876 RKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
Query: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQE----GQVREQEG- 171
+ Q +++ E+E Q+RE++ + + + + +Q+ Q ++Q+ G V + G
Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 992
Query: 172 -----QVREQEGQVREQEGQVREQEGQMGE------------------------------ 196
+++++E + +++ Q ++Q Q
Sbjct: 993 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1052
Query: 197 -------------QEGQMG---EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
+ MG + +++G + + + + + ++ + E+E
Sbjct: 1053 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1112
Query: 241 EQVQKQEEQVQKQEEQMRKQEEQMR------------------EQEEQMREQEEQMLKQK 282
E++ K + V K ++ + EQM ++ E E + +
Sbjct: 1113 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1172
Query: 283 EQTEQEEQTGEQ--EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
T + ++ +Q E + +++ Q R+Q++ ++Q++Q +Q Q +Q++ +W
Sbjct: 1173 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1232
Query: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Q Q Q+ + + +K++++M + + + + MGE
Sbjct: 1233 LHSV----FQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGE 1286
Score = 30.4 bits (67), Expect = 3.3
Identities = 59/296 (19%), Positives = 111/296 (37%), Gaps = 23/296 (7%)
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV----REQEGQVREQEGQVREQE 121
G RE +E R E R+ G+ +EG R+ E E E +E
Sbjct: 150 GGGREMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFRE 209
Query: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
Q E E G R+ E + R RE + R E R+++ ++ G R
Sbjct: 210 EQNGEDEDGGWRLAGSRRDGE-RWRPHSPGWREHMERRRRFEFDFRDRD----DERGYRR 264
Query: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ------MQKQEEQMGEQEEQ-MRKQEE 234
+ G + + E + + EE+MG + + Q+E + E++E R +E
Sbjct: 265 VRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDE 324
Query: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294
GE+ + + K+ ++ K +E E+ R E + + + + G
Sbjct: 325 --GEECSDSEGSHNEEAKEPDKTNK-----KEGEKTDRVGVEASEETPQTSSSSARPGTP 377
Query: 295 EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ 350
+ ++ Q ++E EQ E+ E+ ++ + ++M +Q Q
Sbjct: 378 SDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQ 433
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 131 bits (329), Expect = 1e-30
Identities = 102/346 (29%), Positives = 178/346 (51%), Gaps = 51/346 (14%)
Query: 94 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 153
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 741 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 798
Query: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
++ E+E R+QE +R Q REQE +R
Sbjct: 799 KRR---EEEELARRKQEEALRRQ----REQEIALRR------------------------ 827
Query: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE 273
Q++EE+ +QEE +R+ EE+ E+EE+ +KQEE ++KQEE+ K RE+EE R
Sbjct: 828 --QREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAK---WAREEEEAQRR 881
Query: 274 QEEQMLKQKEQT----EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
EE L+ +E+ +EE+ +E +++ Q+E MR++++Q QE R Q++Q +Q
Sbjct: 882 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQ 938
Query: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ--EEQMRKQEEQMRKQEE 387
QM W Q+ + Q ++QK EE+ +Q EEQ R+Q E M+ ++
Sbjct: 939 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 998
Query: 388 QMRKQEEQM---GEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Q ++Q++++ G + G K + Q+E+ + ++Q ++Q++H
Sbjct: 999 QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQH 1044
Score = 128 bits (322), Expect = 9e-30
Identities = 102/410 (24%), Positives = 210/410 (51%), Gaps = 45/410 (10%)
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
G + + G+V G +QE R+QE Q ++ Q+ +++Q QV
Sbjct: 602 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVL 661
Query: 126 EQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Q+ + +Q+ Q+ Q + + ++ +Q G + E + +
Sbjct: 662 AQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQ 721
Query: 183 ----QEGQVRE---QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
+ G V + G Q+ + E+ + EQ +++ E ++EE+ RK++E+
Sbjct: 722 PTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE 781
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQM--REQEEQMREQEEQMLKQKEQTEQEEQTGE 293
+ Q+E++ ++ Q++EE+ R++EE++ R+QEE +R Q EQ + + Q E+EE+ +
Sbjct: 782 LRRQQEEILRR----QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-Q 836
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
QEE +R EE+ RE+EE+ R+QEE +R+QEE+ K + E + ++ E + +M ++ +
Sbjct: 837 QEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 895
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQM----RKQEEQMRKQEEQM--------GEQKE 401
+ +EE+ +++E +V++Q+E MR++++Q R Q++Q ++Q QM G+Q
Sbjct: 896 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 955
Query: 402 ---------------QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Q E++ + + +EEQ +Q+E M+ ++ +Q++
Sbjct: 956 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 1005
Score = 119 bits (299), Expect = 4e-27
Identities = 93/315 (29%), Positives = 162/315 (51%), Gaps = 51/315 (16%)
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 741 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 798
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
++ E+E +QEE + Q EQ Q++EE+ +QEE +R+ EE+ E+EE+
Sbjct: 799 KRRE---EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER- 854
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMR 299
+KQEE ++KQEE+ K RE+EE R EE L+ +E+ +EE+ +E +++
Sbjct: 855 RKQEELLRKQEEEAAKWA---REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
Query: 300 EQEEQMREQEEQM----REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQEEQ 353
Q+E MR++++Q R Q++Q ++Q QM W Q+ + Q + E Q
Sbjct: 912 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 971
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE-------------------------- 387
E+E + Q +EEQ R+Q E M+ ++Q ++Q++
Sbjct: 972 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1031
Query: 388 -QMRKQEEQMGEQKE 401
QM+KQ++Q + ++
Sbjct: 1032 RQMQKQQQQQQQHQQ 1046
Score = 108 bits (269), Expect = 1e-23
Identities = 88/317 (27%), Positives = 166/317 (52%), Gaps = 20/317 (6%)
Query: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 741 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 798
Query: 112 ----EQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQ 165
E+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E +
Sbjct: 799 KRREEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER 854
Query: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
R+QE +R+QE + + + E + ++ E +M E+ ++ +EE+ +++E ++ Q
Sbjct: 855 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913
Query: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQK 282
+E MR++++Q QE + Q++Q Q+Q QM+ Q+ + Q L +
Sbjct: 914 KELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 970
Query: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
++ E+E + +EEQ R+Q E M+ ++Q ++Q++++ + K E E
Sbjct: 971 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-SGWGNVSKPSGTTKSLLEIQQE 1029
Query: 343 QKEQMWKQEEQMGEQEE 359
+ QM KQ++Q + ++
Sbjct: 1030 EARQMQKQQQQQQQHQQ 1046
Score = 103 bits (258), Expect = 2e-22
Identities = 82/314 (26%), Positives = 166/314 (52%), Gaps = 17/314 (5%)
Query: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR----E 70
E ++L+ + K E + E++ K E ++ +E + R+QE +R Q+ + R E
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREE 803
Query: 71 QEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQE 128
+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E + R+QE
Sbjct: 804 EELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQE 858
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
+R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+ Q+ +R
Sbjct: 859 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
+++ Q QE Q++Q +Q QM+ Q+ + Q ++QK EE
Sbjct: 919 QRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 975
Query: 249 QVQKQ--EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
+ ++Q EEQ R+Q E M+ ++Q ++Q++++ ++ T E +E+ QM+
Sbjct: 976 ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1035
Query: 307 EQEEQMREQEEQMR 320
+Q++Q ++ ++ R
Sbjct: 1036 KQQQQQQQHQQPNR 1049
Score = 92.4 bits (228), Expect = 7e-19
Identities = 75/284 (26%), Positives = 147/284 (51%), Gaps = 12/284 (4%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
+E+ + QEEL+ + E Q +E KR+ E + QE +R Q REQE +R
Sbjct: 772 EEEERKRQEELRRQQEEILRRQQE-EERKRREEEELARRKQEEALRRQ----REQEIALR 826
Query: 70 EQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
Q E + ++QE +R E + RE+E + R+QE +R+QE + + + E + ++ E
Sbjct: 827 RQREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEEN 885
Query: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
++ E+ ++R +E + + +E +V+ Q+ +R+++ ++QE R Q+ Q ++Q Q+
Sbjct: 886 RLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ---QQQEALRRLQQQQQQQQLAQM 942
Query: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ-EEQMRKQEEQMGEQEEQVQKQ 246
+ Q+ + Q ++QK EE+ Q E+ R+Q+ ++ + +Q Q+Q
Sbjct: 943 KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQ 1002
Query: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
++Q + K + E +E+ QM KQ++Q +Q +Q
Sbjct: 1003 QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1046
Score = 77.4 bits (189), Expect = 2e-14
Identities = 83/454 (18%), Positives = 202/454 (44%), Gaps = 39/454 (8%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKE----LKRKLETDKIPLPQEGQVREQEGQVREQE 65
+E+ + +EE +L ++ E +E L+R+ E ++ QE +R E + RE+E
Sbjct: 794 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-QQEEALRRLEERRREEE 852
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
+ R+QE +R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+
Sbjct: 853 ER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Q+ +R+++ ++QE R Q+ Q ++Q Q++ Q+ + Q
Sbjct: 912 RQKELMRQRQ---QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR---KQEEQMGEQEEQ 242
++++ E E+E Q+ +EEQ +Q E M+ ++Q +Q++++ + G +
Sbjct: 969 EIQKLE---EERERQL--REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1023
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK--EQTEQEEQTGEQEEQMRE 300
++ Q+E+ ++ ++Q +Q++Q +Q + R L TG + +
Sbjct: 1024 LEIQQEEARQMQKQ--QQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASD 1081
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
+ + + +++G + + + + ++ + E+EE+
Sbjct: 1082 LVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEK 1141
Query: 361 MQKQEEQVRKQEEQMRKQEEQM------------------RKQEEQMRKQEEQMGEQKEQ 402
+ K + V K ++ + EQM K+ E + + +
Sbjct: 1142 LLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1201
Query: 403 MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
E KE ++ E+ +QK ++Q++ + +Q++
Sbjct: 1202 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQ 1235
Score = 60.8 bits (146), Expect = 2e-09
Identities = 78/478 (16%), Positives = 196/478 (41%), Gaps = 89/478 (18%)
Query: 3 RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQ 60
R+ +E+ QEEL + E E ++ +E +R+LE +++ + +E ++R +E +
Sbjct: 843 RLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 902
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+ +E +V+ Q+ +R+++ Q QE R Q+ Q ++Q Q++ Q+
Sbjct: 903 RKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
Query: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQE----GQVREQEG- 171
+ Q +++ E+E Q+RE++ + + + + +Q+ Q ++Q+ G V + G
Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
Query: 172 -----QVREQEGQVREQEGQVREQEGQMGE------------------------------ 196
+++++E + +++ Q ++Q Q
Sbjct: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1079
Query: 197 -------------QEGQMG---EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
+ MG + +++G + + + + + ++ + E+E
Sbjct: 1080 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139
Query: 241 EQVQKQEEQVQKQEEQMRKQEEQMR------------------EQEEQMREQEEQMLKQK 282
E++ K + V K ++ + EQM ++ E E + +
Sbjct: 1140 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1199
Query: 283 EQTEQEEQTGEQ--EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
T + ++ +Q E + +++ Q R+Q++ ++Q++Q +Q Q +Q++ +W
Sbjct: 1200 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1259
Query: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Q Q Q+ + + +K++++M + + + + MGE
Sbjct: 1260 LHSV----FQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGE 1313
Score = 35.8 bits (81), Expect = 0.078
Identities = 33/193 (17%), Positives = 79/193 (40%), Gaps = 8/193 (4%)
Query: 97 REQEGQVREQEGQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 151
RE + R E R+++ + VR G + + + E + E+E + G
Sbjct: 268 REHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGA 327
Query: 152 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ 211
+ +E + +E + + ++ + + EG E+ + + + GE+ +++G
Sbjct: 328 FLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVA 387
Query: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE---QMREQE 268
E+ + Q ++ + E + + + EQ +K EE+ R + ++ +
Sbjct: 388 SEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRG 447
Query: 269 EQMREQEEQMLKQ 281
++M +Q L Q
Sbjct: 448 DEMVADVQQPLSQ 460
Score = 33.5 bits (75), Expect = 0.39
Identities = 29/172 (16%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Query: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
RE + R E R+++ ++ G R + G + + E + + EE+MG +
Sbjct: 268 REHMERRRRFEFDFRDRD----DERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFD 323
Query: 213 EQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
++K +++ +E++M + GE+ + + K+ ++ K+E + ++
Sbjct: 324 SSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDR 383
Query: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
E+ Q + QE E++++ + ++ + E+E +M
Sbjct: 384 VGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRM 435
Score = 32.3 bits (72), Expect = 0.87
Identities = 35/222 (15%), Positives = 82/222 (36%), Gaps = 31/222 (13%)
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
V ++ E ++ + E R E+ ++E + + E+ G + RE
Sbjct: 212 VGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHM 271
Query: 303 EQMREQEEQMREQEEQ------------------------MREQEEQMGKQEEQ------ 332
E+ R E R+++++ + + EE+MG +
Sbjct: 272 ERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSL 331
Query: 333 MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
QKE + E++E ++ ++ GE+ + + K+ ++ K+E + + ++
Sbjct: 332 KKVQKEPIPEEQEMDFRPVDE-GEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEE 390
Query: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQ 434
Q + G + ++ Q + E +Q E E+
Sbjct: 391 TPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEE 432
Score = 31.6 bits (70), Expect = 1.5
Identities = 31/194 (15%), Positives = 76/194 (39%), Gaps = 5/194 (2%)
Query: 90 REQEGQVREQEGQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 144
RE + R E R+++ + VR G + + + E + E+E + G
Sbjct: 268 REHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGA 327
Query: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204
+ +E + +E + + ++ + + EG E+ + + + GE+ ++G
Sbjct: 328 FLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVA 387
Query: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
E+ + + Q ++ + E + + EQ +K EE+ + + K +
Sbjct: 388 SEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRG 447
Query: 265 REQEEQMREQEEQM 278
E +++ Q+
Sbjct: 448 DEMVADVQQPLSQI 461
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 131 bits (329), Expect = 1e-30
Identities = 102/346 (29%), Positives = 178/346 (51%), Gaps = 51/346 (14%)
Query: 94 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 153
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 720 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
Query: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
++ E+E R+QE +R Q REQE +R
Sbjct: 778 KRR---EEEELARRKQEEALRRQ----REQEIALRR------------------------ 806
Query: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE 273
Q++EE+ +QEE +R+ EE+ E+EE+ +KQEE ++KQEE+ K RE+EE R
Sbjct: 807 --QREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAK---WAREEEEAQRR 860
Query: 274 QEEQMLKQKEQT----EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
EE L+ +E+ +EE+ +E +++ Q+E MR++++Q QE R Q++Q +Q
Sbjct: 861 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQ 917
Query: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ--EEQMRKQEEQMRKQEE 387
QM W Q+ + Q ++QK EE+ +Q EEQ R+Q E M+ ++
Sbjct: 918 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 977
Query: 388 QMRKQEEQM---GEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Q ++Q++++ G + G K + Q+E+ + ++Q ++Q++H
Sbjct: 978 QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQH 1023
Score = 128 bits (322), Expect = 9e-30
Identities = 102/410 (24%), Positives = 210/410 (51%), Gaps = 45/410 (10%)
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
G + + G+V G +QE R+QE Q ++ Q+ +++Q QV
Sbjct: 581 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVL 640
Query: 126 EQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Q+ + +Q+ Q+ Q + + ++ +Q G + E + +
Sbjct: 641 AQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQ 700
Query: 183 ----QEGQVRE---QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
+ G V + G Q+ + E+ + EQ +++ E ++EE+ RK++E+
Sbjct: 701 PTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE 760
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQM--REQEEQMREQEEQMLKQKEQTEQEEQTGE 293
+ Q+E++ ++ Q++EE+ R++EE++ R+QEE +R Q EQ + + Q E+EE+ +
Sbjct: 761 LRRQQEEILRR----QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-Q 815
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
QEE +R EE+ RE+EE+ R+QEE +R+QEE+ K + E + ++ E + +M ++ +
Sbjct: 816 QEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQM----RKQEEQMRKQEEQM--------GEQKE 401
+ +EE+ +++E +V++Q+E MR++++Q R Q++Q ++Q QM G+Q
Sbjct: 875 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 934
Query: 402 ---------------QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Q E++ + + +EEQ +Q+E M+ ++ +Q++
Sbjct: 935 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
Score = 119 bits (299), Expect = 4e-27
Identities = 93/315 (29%), Positives = 162/315 (51%), Gaps = 51/315 (16%)
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 720 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
++ E+E +QEE + Q EQ Q++EE+ +QEE +R+ EE+ E+EE+
Sbjct: 778 KRRE---EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER- 833
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMR 299
+KQEE ++KQEE+ K RE+EE R EE L+ +E+ +EE+ +E +++
Sbjct: 834 RKQEELLRKQEEEAAKWA---REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Query: 300 EQEEQMREQEEQM----REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQEEQ 353
Q+E MR++++Q R Q++Q ++Q QM W Q+ + Q + E Q
Sbjct: 891 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 950
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE-------------------------- 387
E+E + Q +EEQ R+Q E M+ ++Q ++Q++
Sbjct: 951 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1010
Query: 388 -QMRKQEEQMGEQKE 401
QM+KQ++Q + ++
Sbjct: 1011 RQMQKQQQQQQQHQQ 1025
Score = 108 bits (269), Expect = 1e-23
Identities = 88/317 (27%), Positives = 166/317 (52%), Gaps = 20/317 (6%)
Query: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 720 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
Query: 112 ----EQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQ 165
E+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E +
Sbjct: 778 KRREEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER 833
Query: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
R+QE +R+QE + + + E + ++ E +M E+ ++ +EE+ +++E ++ Q
Sbjct: 834 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
Query: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQK 282
+E MR++++Q QE + Q++Q Q+Q QM+ Q+ + Q L +
Sbjct: 893 KELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 949
Query: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
++ E+E + +EEQ R+Q E M+ ++Q ++Q++++ + K E E
Sbjct: 950 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-SGWGNVSKPSGTTKSLLEIQQE 1008
Query: 343 QKEQMWKQEEQMGEQEE 359
+ QM KQ++Q + ++
Sbjct: 1009 EARQMQKQQQQQQQHQQ 1025
Score = 103 bits (258), Expect = 2e-22
Identities = 82/314 (26%), Positives = 166/314 (52%), Gaps = 17/314 (5%)
Query: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR----E 70
E ++L+ + K E + E++ K E ++ +E + R+QE +R Q+ + R E
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREE 782
Query: 71 QEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQE 128
+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E + R+QE
Sbjct: 783 EELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQE 837
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
+R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+ Q+ +R
Sbjct: 838 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
+++ Q QE Q++Q +Q QM+ Q+ + Q ++QK EE
Sbjct: 898 QRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 954
Query: 249 QVQKQ--EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
+ ++Q EEQ R+Q E M+ ++Q ++Q++++ ++ T E +E+ QM+
Sbjct: 955 ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1014
Query: 307 EQEEQMREQEEQMR 320
+Q++Q ++ ++ R
Sbjct: 1015 KQQQQQQQHQQPNR 1028
Score = 77.4 bits (189), Expect = 2e-14
Identities = 83/454 (18%), Positives = 202/454 (44%), Gaps = 39/454 (8%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKE----LKRKLETDKIPLPQEGQVREQEGQVREQE 65
+E+ + +EE +L ++ E +E L+R+ E ++ QE +R E + RE+E
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-QQEEALRRLEERRREEE 831
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
+ R+QE +R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+
Sbjct: 832 ER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Q+ +R+++ ++QE R Q+ Q ++Q Q++ Q+ + Q
Sbjct: 891 RQKELMRQRQ---QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR---KQEEQMGEQEEQ 242
++++ E E+E Q+ +EEQ +Q E M+ ++Q +Q++++ + G +
Sbjct: 948 EIQKLE---EERERQL--REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK--EQTEQEEQTGEQEEQMRE 300
++ Q+E+ ++ ++Q +Q++Q +Q + R L TG + +
Sbjct: 1003 LEIQQEEARQMQKQ--QQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASD 1060
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
+ + + +++G + + + + ++ + E+EE+
Sbjct: 1061 LVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEK 1120
Query: 361 MQKQEEQVRKQEEQMRKQEEQM------------------RKQEEQMRKQEEQMGEQKEQ 402
+ K + V K ++ + EQM K+ E + + +
Sbjct: 1121 LLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1180
Query: 403 MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
E KE ++ E+ +QK ++Q++ + +Q++
Sbjct: 1181 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQ 1214
Score = 60.8 bits (146), Expect = 2e-09
Identities = 78/478 (16%), Positives = 196/478 (41%), Gaps = 89/478 (18%)
Query: 3 RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQ 60
R+ +E+ QEEL + E E ++ +E +R+LE +++ + +E ++R +E +
Sbjct: 822 RLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 881
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+ +E +V+ Q+ +R+++ Q QE R Q+ Q ++Q Q++ Q+
Sbjct: 882 RKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQE----GQVREQEG- 171
+ Q +++ E+E Q+RE++ + + + + +Q+ Q ++Q+ G V + G
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
Query: 172 -----QVREQEGQVREQEGQVREQEGQMGE------------------------------ 196
+++++E + +++ Q ++Q Q
Sbjct: 999 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1058
Query: 197 -------------QEGQMG---EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
+ MG + +++G + + + + + ++ + E+E
Sbjct: 1059 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1118
Query: 241 EQVQKQEEQVQKQEEQMRKQEEQMR------------------EQEEQMREQEEQMLKQK 282
E++ K + V K ++ + EQM ++ E E + +
Sbjct: 1119 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1178
Query: 283 EQTEQEEQTGEQ--EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
T + ++ +Q E + +++ Q R+Q++ ++Q++Q +Q Q +Q++ +W
Sbjct: 1179 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1238
Query: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Q Q Q+ + + +K++++M + + + + MGE
Sbjct: 1239 LHSV----FQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGE 1292
Score = 31.6 bits (70), Expect = 1.5
Identities = 31/197 (15%), Positives = 78/197 (39%), Gaps = 8/197 (4%)
Query: 90 REQEGQVREQEGQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 144
RE + R E R+++ + VR G + + + E + E+E + G
Sbjct: 246 REHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGA 305
Query: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204
+ +E + +E + + ++ + + EG E+ + + + GE+ ++G
Sbjct: 306 FLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVG-- 363
Query: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
+ E+ Q + G + ++ Q ++E +Q E+ +++ ++
Sbjct: 364 -VEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKV 422
Query: 265 REQEEQMREQEEQMLKQ 281
+ ++M +Q L Q
Sbjct: 423 PSRGDEMVADVQQPLSQ 439
Score = 29.6 bits (65), Expect = 5.6
Identities = 37/205 (18%), Positives = 81/205 (39%), Gaps = 18/205 (8%)
Query: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
RE + R E R+++ ++ G R + G + + E + + EE+MG +
Sbjct: 246 REHMERRRRFEFDFRDRD----DERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFD 301
Query: 213 EQ------MQKQEEQMGEQEEQ-MRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
+ Q+E + E++E R +E GE+ + + K+ ++ K +
Sbjct: 302 SSGAFLSLKKVQKEPIPEEQEMDFRPVDE--GEECSDSEGSHNEEAKEPDKTNK-----K 354
Query: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ 325
E E+ R E + + + + G + ++ Q ++E EQ E+ E+
Sbjct: 355 EGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRM 414
Query: 326 MGKQEEQMWEQKEQMWEQKEQMWKQ 350
++ + ++M +Q Q
Sbjct: 415 ENSLPAKVPSRGDEMVADVQQPLSQ 439
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 131 bits (329), Expect = 1e-30
Identities = 102/346 (29%), Positives = 178/346 (51%), Gaps = 51/346 (14%)
Query: 94 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 153
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 720 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
Query: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
++ E+E R+QE +R Q REQE +R
Sbjct: 778 KRR---EEEELARRKQEEALRRQ----REQEIALRR------------------------ 806
Query: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE 273
Q++EE+ +QEE +R+ EE+ E+EE+ +KQEE ++KQEE+ K RE+EE R
Sbjct: 807 --QREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAK---WAREEEEAQRR 860
Query: 274 QEEQMLKQKEQT----EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
EE L+ +E+ +EE+ +E +++ Q+E MR++++Q QE R Q++Q +Q
Sbjct: 861 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQ 917
Query: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ--EEQMRKQEEQMRKQEE 387
QM W Q+ + Q ++QK EE+ +Q EEQ R+Q E M+ ++
Sbjct: 918 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 977
Query: 388 QMRKQEEQM---GEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Q ++Q++++ G + G K + Q+E+ + ++Q ++Q++H
Sbjct: 978 QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQH 1023
Score = 128 bits (322), Expect = 9e-30
Identities = 102/410 (24%), Positives = 210/410 (51%), Gaps = 45/410 (10%)
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
G + + G+V G +QE R+QE Q ++ Q+ +++Q QV
Sbjct: 581 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVL 640
Query: 126 EQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Q+ + +Q+ Q+ Q + + ++ +Q G + E + +
Sbjct: 641 AQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQ 700
Query: 183 ----QEGQVRE---QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
+ G V + G Q+ + E+ + EQ +++ E ++EE+ RK++E+
Sbjct: 701 PTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE 760
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQM--REQEEQMREQEEQMLKQKEQTEQEEQTGE 293
+ Q+E++ ++ Q++EE+ R++EE++ R+QEE +R Q EQ + + Q E+EE+ +
Sbjct: 761 LRRQQEEILRR----QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-Q 815
Query: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
QEE +R EE+ RE+EE+ R+QEE +R+QEE+ K + E + ++ E + +M ++ +
Sbjct: 816 QEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQM----RKQEEQMRKQEEQM--------GEQKE 401
+ +EE+ +++E +V++Q+E MR++++Q R Q++Q ++Q QM G+Q
Sbjct: 875 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 934
Query: 402 ---------------QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Q E++ + + +EEQ +Q+E M+ ++ +Q++
Sbjct: 935 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
Score = 119 bits (299), Expect = 4e-27
Identities = 93/315 (29%), Positives = 162/315 (51%), Gaps = 51/315 (16%)
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 720 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
++ E+E +QEE + Q EQ Q++EE+ +QEE +R+ EE+ E+EE+
Sbjct: 778 KRRE---EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER- 833
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMR 299
+KQEE ++KQEE+ K RE+EE R EE L+ +E+ +EE+ +E +++
Sbjct: 834 RKQEELLRKQEEEAAKWA---REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Query: 300 EQEEQMREQEEQM----REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQEEQ 353
Q+E MR++++Q R Q++Q ++Q QM W Q+ + Q + E Q
Sbjct: 891 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 950
Query: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE-------------------------- 387
E+E + Q +EEQ R+Q E M+ ++Q ++Q++
Sbjct: 951 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1010
Query: 388 -QMRKQEEQMGEQKE 401
QM+KQ++Q + ++
Sbjct: 1011 RQMQKQQQQQQQHQQ 1025
Score = 108 bits (269), Expect = 1e-23
Identities = 88/317 (27%), Positives = 166/317 (52%), Gaps = 20/317 (6%)
Query: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111
G EQ Q+ + + EQE RE E + + +E + + QE R+QE +R Q+ + R
Sbjct: 720 GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
Query: 112 ----EQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQ 165
E+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E +
Sbjct: 778 KRREEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER 833
Query: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
R+QE +R+QE + + + E + ++ E +M E+ ++ +EE+ +++E ++ Q
Sbjct: 834 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
Query: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQK 282
+E MR++++Q QE + Q++Q Q+Q QM+ Q+ + Q L +
Sbjct: 893 KELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 949
Query: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
++ E+E + +EEQ R+Q E M+ ++Q ++Q++++ + K E E
Sbjct: 950 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-SGWGNVSKPSGTTKSLLEIQQE 1008
Query: 343 QKEQMWKQEEQMGEQEE 359
+ QM KQ++Q + ++
Sbjct: 1009 EARQMQKQQQQQQQHQQ 1025
Score = 103 bits (258), Expect = 2e-22
Identities = 82/314 (26%), Positives = 166/314 (52%), Gaps = 17/314 (5%)
Query: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR----E 70
E ++L+ + K E + E++ K E ++ +E + R+QE +R Q+ + R E
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREE 782
Query: 71 QEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQE 128
+E R+QE +R Q REQE +R Q E + ++QE +R E + RE+E + R+QE
Sbjct: 783 EELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQE 837
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
+R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+ Q+ +R
Sbjct: 838 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897
Query: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
+++ Q QE Q++Q +Q QM+ Q+ + Q ++QK EE
Sbjct: 898 QRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 954
Query: 249 QVQKQ--EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
+ ++Q EEQ R+Q E M+ ++Q ++Q++++ ++ T E +E+ QM+
Sbjct: 955 ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1014
Query: 307 EQEEQMREQEEQMR 320
+Q++Q ++ ++ R
Sbjct: 1015 KQQQQQQQHQQPNR 1028
Score = 77.4 bits (189), Expect = 2e-14
Identities = 83/454 (18%), Positives = 202/454 (44%), Gaps = 39/454 (8%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKE----LKRKLETDKIPLPQEGQVREQEGQVREQE 65
+E+ + +EE +L ++ E +E L+R+ E ++ QE +R E + RE+E
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-QQEEALRRLEERRREEE 831
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
+ R+QE +R+QE + + + E + ++ E ++ E+ ++R +E + + +E +V+
Sbjct: 832 ER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Q+ +R+++ ++QE R Q+ Q ++Q Q++ Q+ + Q
Sbjct: 891 RQKELMRQRQ---QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR---KQEEQMGEQEEQ 242
++++ E E+E Q+ +EEQ +Q E M+ ++Q +Q++++ + G +
Sbjct: 948 EIQKLE---EERERQL--REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK--EQTEQEEQTGEQEEQMRE 300
++ Q+E+ ++ ++Q +Q++Q +Q + R L TG + +
Sbjct: 1003 LEIQQEEARQMQKQ--QQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASD 1060
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
+ + + +++G + + + + ++ + E+EE+
Sbjct: 1061 LVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEK 1120
Query: 361 MQKQEEQVRKQEEQMRKQEEQM------------------RKQEEQMRKQEEQMGEQKEQ 402
+ K + V K ++ + EQM K+ E + + +
Sbjct: 1121 LLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1180
Query: 403 MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
E KE ++ E+ +QK ++Q++ + +Q++
Sbjct: 1181 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQ 1214
Score = 60.8 bits (146), Expect = 2e-09
Identities = 78/478 (16%), Positives = 196/478 (41%), Gaps = 89/478 (18%)
Query: 3 RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQ 60
R+ +E+ QEEL + E E ++ +E +R+LE +++ + +E ++R +E +
Sbjct: 822 RLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 881
Query: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
+ +E +V+ Q+ +R+++ Q QE R Q+ Q ++Q Q++ Q+
Sbjct: 882 RKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 121 EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQE----GQVREQEG- 171
+ Q +++ E+E Q+RE++ + + + + +Q+ Q ++Q+ G V + G
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
Query: 172 -----QVREQEGQVREQEGQVREQEGQMGE------------------------------ 196
+++++E + +++ Q ++Q Q
Sbjct: 999 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1058
Query: 197 -------------QEGQMG---EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
+ MG + +++G + + + + + ++ + E+E
Sbjct: 1059 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1118
Query: 241 EQVQKQEEQVQKQEEQMRKQEEQMR------------------EQEEQMREQEEQMLKQK 282
E++ K + V K ++ + EQM ++ E E + +
Sbjct: 1119 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1178
Query: 283 EQTEQEEQTGEQ--EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
T + ++ +Q E + +++ Q R+Q++ ++Q++Q +Q Q +Q++ +W
Sbjct: 1179 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1238
Query: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Q Q Q+ + + +K++++M + + + + MGE
Sbjct: 1239 LHSV----FQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGE 1292
Score = 31.6 bits (70), Expect = 1.5
Identities = 31/197 (15%), Positives = 78/197 (39%), Gaps = 8/197 (4%)
Query: 90 REQEGQVREQEGQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 144
RE + R E R+++ + VR G + + + E + E+E + G
Sbjct: 246 REHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGA 305
Query: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204
+ +E + +E + + ++ + + EG E+ + + + GE+ ++G
Sbjct: 306 FLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVG-- 363
Query: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
+ E+ Q + G + ++ Q ++E +Q E+ +++ ++
Sbjct: 364 -VEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKV 422
Query: 265 REQEEQMREQEEQMLKQ 281
+ ++M +Q L Q
Sbjct: 423 PSRGDEMVADVQQPLSQ 439
Score = 29.6 bits (65), Expect = 5.6
Identities = 37/205 (18%), Positives = 81/205 (39%), Gaps = 18/205 (8%)
Query: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
RE + R E R+++ ++ G R + G + + E + + EE+MG +
Sbjct: 246 REHMERRRRFEFDFRDRD----DERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFD 301
Query: 213 EQ------MQKQEEQMGEQEEQ-MRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
+ Q+E + E++E R +E GE+ + + K+ ++ K +
Sbjct: 302 SSGAFLSLKKVQKEPIPEEQEMDFRPVDE--GEECSDSEGSHNEEAKEPDKTNK-----K 354
Query: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ 325
E E+ R E + + + + G + ++ Q ++E EQ E+ E+
Sbjct: 355 EGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRM 414
Query: 326 MGKQEEQMWEQKEQMWEQKEQMWKQ 350
++ + ++M +Q Q
Sbjct: 415 ENSLPAKVPSRGDEMVADVQQPLSQ 439
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 129 bits (323), Expect = 7e-30
Identities = 109/423 (25%), Positives = 211/423 (49%), Gaps = 21/423 (4%)
Query: 5 TNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ 64
+NE+LK++ +EL+E+L+++ TEK+ +QL+++EL++KLE ++ L Q+ R + +Q
Sbjct: 306 SNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLL-QQFSSRCEAPDANQQ 364
Query: 65 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
Q E+ Q+ GQV E Q++ + + E ++ + R++ Q+ EQ +
Sbjct: 365 LQQAMEERAQLEAHLGQVMESVRQLQMERDKYAEN---LKGESAMWRQRMQQMSEQVHTL 421
Query: 125 REQE----GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
RE++ +V+E E + E Q+ E EQ+ Q E E +E EG
Sbjct: 422 REEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQA-EAEHLRKELEGLA 480
Query: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
+ + QV++ EG EQEE++ E +++ E GEQ E R+ E M
Sbjct: 481 GQLQAQVQDNEGLSRLNR----EQEERLLE----LERAAELWGEQAEARRQILETMQNDR 532
Query: 241 EQVQKQEEQVQKQEEQMRK-QEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
+ + Q ++ +EQ+ + Q ++ E M +Q + E ++ GE +E++
Sbjct: 533 TTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLS 592
Query: 300 EQEE--QMREQEEQ-MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE 356
E +E +++ QE Q +++Q +Q +Q +Q+ +KE + Q + +Q+ +
Sbjct: 593 ELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQ 652
Query: 357 QEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQ 416
QE Q + E R++ ++ +++ E +Q +Q+R Q M E G +E+ ++EE+
Sbjct: 653 QEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEEEE 712
Query: 417 MGE 419
E
Sbjct: 713 EEE 715
Score = 95.9 bits (237), Expect = 6e-20
Identities = 110/490 (22%), Positives = 225/490 (45%), Gaps = 69/490 (14%)
Query: 4 ITNEELKEKNAELQEELQLVETE--------KSEIQLHIKEL----KRKLETDKIPLPQE 51
IT E+LK++N E+ ++L+ + E + ++Q+HI+ + K E +
Sbjct: 182 ITIEKLKQQNQEITDQLEEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQ 241
Query: 52 GQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR---- 104
R++EG+ + ++ R + G++ V Q+ + ++ ++ +R
Sbjct: 242 HAARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELY 301
Query: 105 ---EQEGQVREQEGQVREQ-EGQVREQEG-QVREQEGQVREQEGQVREQEGQVREQEGQV 159
+ +++++ ++ E+ V E+ G Q+ +E Q + + ++ Q+ R +
Sbjct: 302 KNTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDA 361
Query: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ---EGQMGEQE-EQMGEQEEQM 215
+Q Q E+ Q+ GQV E Q++ + + E E M Q +QM EQ +
Sbjct: 362 NQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTL 421
Query: 216 QKQEE----QMGEQEEQMRKQEEQMGEQ------------EEQVQKQEEQVQKQEEQMRK 259
++++E ++ E E + + QM E E+Q+Q + E ++K+ E +
Sbjct: 422 REEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAG 481
Query: 260 QEEQMREQEEQM----REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
Q + + E + REQEE++L E E GEQ E R+ E M+ +
Sbjct: 482 QLQAQVQDNEGLSRLNREQEERLL---ELERAAELWGEQAEARRQILETMQNDRTTISRA 538
Query: 316 EEQMREQEEQMGKQEEQMWEQKEQMWE-----QKEQMWKQE--EQMGEQEEQMQKQEE-- 366
Q RE +EQ+ + + + + E Q EQ K+E +++GE +E++ + +E
Sbjct: 539 LSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSELKETV 598
Query: 367 QVRKQEEQ-MRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ-------KEQMREQEEQMG 418
+++ QE Q +++Q +Q +Q +Q+ +KE + Q +Q+++QE Q G
Sbjct: 599 ELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQEAQ-G 657
Query: 419 EQKEQMRKQE 428
+ +M +QE
Sbjct: 658 KAVAEMARQE 667
Score = 93.2 bits (230), Expect = 4e-19
Identities = 104/471 (22%), Positives = 216/471 (45%), Gaps = 62/471 (13%)
Query: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
+ + EL+ L V T++ + + KEL ++ + ++ L + Q E +++++ ++
Sbjct: 262 RRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNED---LKQEKSELE 318
Query: 70 EQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 128
E+ V E+ G Q+ +E Q + + ++ Q+ R + +Q Q E+
Sbjct: 319 EKLRVLVTEKAGM------QLNLEELQKKLEMTELLLQQFSSRCEAPDANQQLQQAMEER 372
Query: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE---- 184
Q+ GQV E Q++ + + E ++ + R++ Q+ EQ +RE++
Sbjct: 373 AQLEAHLGQVMESVRQLQMERDKYAEN---LKGESAMWRQRMQQMSEQVHTLREEKECSM 429
Query: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQM-GEQEEQV 243
+V+E E + E QM E E + E+Q+ + E +RK+ E + G+ + QV
Sbjct: 430 SRVQELETSLAELRNQMAEPPPP--EPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQV 487
Query: 244 QKQEEQVQKQEEQMRKQEEQMREQEE--QMREQEEQMLKQKEQTEQEEQT--GEQEEQMR 299
Q E + R+QEE++ E E ++ ++ + +Q +T Q ++T Q R
Sbjct: 488 QDNEGLSRLN----REQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQNR 543
Query: 300 EQEEQMREQE--------------EQMREQEEQMREQEEQMGKQEEQMWEQKE------- 338
E +EQ+ E + ++ ++ RE +++G+ +E++ E KE
Sbjct: 544 ELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSELKETVELKSQ 603
Query: 339 ---QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ-------EEQMRKQEEQMRKQEEQ 388
+ +Q++Q +Q +Q+ ++E + Q +Q+++QE Q + E
Sbjct: 604 EAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQEAQGKAVAEM 663
Query: 389 MRKQEEQMGEQKEQMGEQKEQMREQEEQM---GEQKEQMRKQEEHMGEQKE 436
R++ ++ E+ E +Q +Q+R Q M GE R++EE E++E
Sbjct: 664 ARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEEE 714
Score = 69.3 bits (168), Expect = 6e-12
Identities = 80/469 (17%), Positives = 196/469 (41%), Gaps = 86/469 (18%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
+++ E+ L+EE + + E++ + EL+ ++ P P G ++ E E
Sbjct: 412 QQMSEQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEH 471
Query: 67 QVREQEGQVREQEGQVREQEGQVR---EQEGQVREQE------GQVREQEGQVREQEGQV 117
+E EG + + QV++ EG R EQE ++ E E G+ E Q+ E
Sbjct: 472 LRKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQND 531
Query: 118 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 177
R + Q +++EQ +++ ++ + ++ + + ++ ++ G+++E+
Sbjct: 532 RTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKL 591
Query: 178 GQVREQEGQVREQEGQMGEQEGQ--MGEQEEQMGEQEEQMQKQE-------------EQM 222
+++E +++ QE Q +Q+ +G ++ + ++ ++E +Q+
Sbjct: 592 SELKETV-ELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQL 650
Query: 223 GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM----------REQEEQMR 272
+QE Q + E ++ ++ Q++ E +Q +Q+R Q M RE+EE
Sbjct: 651 QQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEE 710
Query: 273 EQEEQM-------------LKQKEQ---------TEQEEQTGEQEEQMREQEEQMR---- 306
E+EE+ L+ +E EE+ Q++EQ + R
Sbjct: 711 EEEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAH 770
Query: 307 -------------------------EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
E ++ E+++ + ++ +++ + E+ E++
Sbjct: 771 LLASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELE 830
Query: 342 EQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMR 390
+ Q+ + + +GE Q Q ++++ + + ++ + +E+M+
Sbjct: 831 HRCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMK 879
Score = 64.7 bits (156), Expect = 2e-10
Identities = 53/297 (17%), Positives = 143/297 (48%), Gaps = 22/297 (7%)
Query: 159 VREQEGQVREQEGQVREQEGQVREQEGQVREQ----EGQMGEQEGQMGEQEEQMGEQEEQ 214
+ + + Q +E Q+ E++ + +++G +REQ +G + E + + +
Sbjct: 184 IEKLKQQNQEITDQLEEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQHA 243
Query: 215 MQKQEEQMGEQEEQMRKQEEQMGEQE---EQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271
+++E + + +++ ++GE E V Q+++ + +++ K+ + +R + +
Sbjct: 244 ARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKN 303
Query: 272 REQEEQMLKQKEQTEQEEQ---TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328
+ E + ++K + E++ + T + Q+ +E Q + + ++ Q+ R + +
Sbjct: 304 TQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQ 363
Query: 329 QEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Q +Q E++ Q+ Q+ + Q+ + + K E ++ + R++ +QM +Q
Sbjct: 364 QLQQAMEERAQLEAHLGQVMESVRQL---QMERDKYAENLKGESAMWRQRMQQMSEQVHT 420
Query: 389 MRKQEE----QMGEQKEQMGEQKEQMRE---QEEQMG--EQKEQMRKQEEHMGEQKE 436
+R+++E ++ E + + E + QM E E G E ++Q++ + EH+ ++ E
Sbjct: 421 LREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELE 477
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/302 (18%), Positives = 126/302 (41%), Gaps = 43/302 (14%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQL-------HIKELK---RKLETDKIPLPQEGQVREQ 57
EL+EK +EL+E ++L E +Q H+++ ++L ++K L + ++ Q
Sbjct: 586 ELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQ 645
Query: 58 -EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQVREQ 113
Q+++QE Q + R++ + +E+ +Q Q+R Q + E +G RE+
Sbjct: 646 LVDQLQQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREE 705
Query: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 173
E E+E + + + +E V V E + GQ++EQ +
Sbjct: 706 EEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRC 765
Query: 174 R-----------EQEGQV---------------REQEGQVREQEGQMGEQEGQMGEQEEQ 207
R E E R +G + + + + E + + +E+
Sbjct: 766 RRLAHLLASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKER 825
Query: 208 MGEQEE---QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
+ E E Q+ + + +GE + Q + E+ + ++ ++ + +E+M+ + ++
Sbjct: 826 VEELEHRCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLLEL 885
Query: 265 RE 266
+E
Sbjct: 886 QE 887
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 128 bits (322), Expect = 9e-30
Identities = 104/457 (22%), Positives = 224/457 (49%), Gaps = 34/457 (7%)
Query: 9 LKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ---EGQVREQEGQVREQE 65
L+E A L + L E E ++ I+EL+++ E K L + + R QE +++++
Sbjct: 1419 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQ 1478
Query: 66 GQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
Q E+ V E V+E+E ++ Q Q+RE E Q + Q ++ +++ +
Sbjct: 1479 IQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMI 1538
Query: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQ---VREQEGQVREQEGQVREQEGQVR 181
Q GQV++ + Q+ E E E + E Q ++E EGQ Q + +
Sbjct: 1539 ESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLE 1598
Query: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
E+ +++ Q Q+ + E ++ E++++++ Q EQ+ E + Q + + +++
Sbjct: 1599 ERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQ 1658
Query: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQ----MREQEEQMLKQKE--QTEQEEQTGEQE 295
++ Q+E++Q E+Q +Q + + E EQ +RE+ ++ Q++ Q EE G +
Sbjct: 1659 ELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSK 1718
Query: 296 EQMREQEEQ---MREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Q E +R++E+++ Q+E + E +E + E+Q+ ++ E + ++E+
Sbjct: 1719 AQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQ 1778
Query: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQ------MRKQEEQMRKQEEQMGEQKEQMGEQ 406
++ ++Q+Q+ EQ +E+ ++ Q ++ R QE + +QE+Q + +E+ ++
Sbjct: 1779 EIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE 1838
Query: 407 KEQ------------MREQEEQMGEQKEQMRKQEEHM 431
K ++E+ ++ + KEQ R+ EE +
Sbjct: 1839 KADALQGALEQAHMTLKERHGELQDHKEQARRLEEEL 1875
Score = 125 bits (313), Expect = 1e-28
Identities = 108/470 (22%), Positives = 235/470 (50%), Gaps = 46/470 (9%)
Query: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
R LK KN E++ E + + + + +L + + K L+ + L Q + E+E +V
Sbjct: 1382 RTARSALKLKNEEVESERERAQALQEQGELKVAQGKA-LQENLALLTQT--LAEREEEVE 1438
Query: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG----------QVRE 112
GQ++E E Q Q+ + ++++ +V Q+ Q++E E V+E
Sbjct: 1439 TLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQE 1498
Query: 113 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 172
+E ++ Q Q+RE E Q + Q ++ +++ + Q GQV++ + Q+ E
Sbjct: 1499 REQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECL 1558
Query: 173 VREQEGQVREQEGQ---VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229
E E + E Q ++E EGQ Q + + E+ +++Q Q Q+ + E
Sbjct: 1559 ALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHS 1618
Query: 230 RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEE 289
++ E++++V+ Q EQ+ E++++Q+E + + E+ R+QE + K++ Q +++
Sbjct: 1619 TVLARELQERDQEVKSQREQI----EELQRQKEHLTQDLER-RDQELMLQKERIQVLEDQ 1673
Query: 290 QTGEQ---EEQMREQEEQMREQEEQMREQEEQMREQEEQMGK-----QEEQMWEQKEQMW 341
+T + EE + + + +RE+ ++ Q + M+E+ E+ GK Q + K +
Sbjct: 1674 RTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEE-GKGPSKAQRGSLEHMKLILR 1732
Query: 342 EQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
++++++ Q+E + E +E + E+Q++ ++ + + ++E+++ ++Q+ E +E
Sbjct: 1733 DKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEARE 1792
Query: 402 QMGEQKEQ--------------MREQE-EQMGEQKEQMRKQEEHMGEQKE 436
Q GE KEQ R+QE E + ++++Q + QEE + E+ +
Sbjct: 1793 Q-GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841
Score = 123 bits (308), Expect = 4e-28
Identities = 102/470 (21%), Positives = 238/470 (50%), Gaps = 49/470 (10%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRK-----LETDKIPLPQEGQVREQ---EG 59
EL+E++ E++ + + +E + + + ++L+R+ L+ ++I + ++ + R+ E
Sbjct: 1624 ELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEE 1683
Query: 60 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 119
+ + + +RE+ ++ Q ++E+ E +G + Q G + + +R++E +V
Sbjct: 1684 DLEQIKLSLRERGRELTTQRQLMQER---AEEGKGPSKAQRGSLEHMKLILRDKEKEVEC 1740
Query: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQV------REQEGQVREQEGQVREQEGQV 173
Q+ + E ++E + Q+ +Q + + G+ REQE V +Q+ Q ++G++
Sbjct: 1741 QQEHIHE----LQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGEL 1796
Query: 174 REQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE 233
+EQ Q + E Q R + E E EQ++ G++E +K + G E+ +
Sbjct: 1797 KEQSLQSQLDEAQ-RALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLK 1855
Query: 234 EQMGE---QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
E+ GE +EQ ++ EE++ + +++ EE + + + REQE+ +L ++Q ++ Q
Sbjct: 1856 ERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQ 1915
Query: 291 TGEQEEQM--------------REQE-EQMREQEEQMREQEEQMREQ----EEQMGKQEE 331
E E + R+QE E +R + + R QEE R + +E +GK
Sbjct: 1916 EHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHA 1975
Query: 332 QMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQ----EE 387
+ +++ + EQ E E + + + R+ EE +R QE +++ Q +E
Sbjct: 1976 ALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQE 2035
Query: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ-KEQMRKQEEHMGEQKE 436
+++ ++ + ++ E++ Q+E+ + E+ + ++ +E M ++++++G+++E
Sbjct: 2036 DVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQERE 2085
Score = 118 bits (295), Expect = 1e-26
Identities = 93/464 (20%), Positives = 225/464 (48%), Gaps = 36/464 (7%)
Query: 5 TNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ-EGQVREQEGQVRE 63
T + L+++ +L+E L E EKS++ +++L+R+L ++ + EG+ E ++ E
Sbjct: 1258 TRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME 1317
Query: 64 QEGQVREQEGQVREQEGQVREQEG--------------QVREQEGQVREQEGQ-----VR 104
+ + ++R E Q E +G QV + V E Q +
Sbjct: 1318 LHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGIL 1377
Query: 105 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-----GQVREQEGQV 159
E++ + +++ +E + + Q +++G+++ +G+ ++ + E+E +V
Sbjct: 1378 EEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEV 1437
Query: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE---QMQ 216
GQ++E E Q Q+ + ++++ ++ Q+ Q+ E E+ E +Q
Sbjct: 1438 ETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQ 1497
Query: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEE 276
++E+++ Q EQ+R+ E+ Q ++ Q +++K+++ + Q Q+++ ++Q+ E
Sbjct: 1498 EREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLEC 1557
Query: 277 QMLKQKEQTE----QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQ 332
L+ +E Q++ E E Q Q + + E+ ++++ Q Q+ E
Sbjct: 1558 LALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESH 1617
Query: 333 MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
++ E+ +++ Q EQ+ E + Q + + + ++++++ Q+E+++ E+Q +Q
Sbjct: 1618 STVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQ 1677
Query: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ-EEHMGEQK 435
+ + E EQ+ K +RE+ ++ Q++ M+++ EE G K
Sbjct: 1678 TKILEEDLEQI---KLSLRERGRELTTQRQLMQERAEEGKGPSK 1718
Score = 115 bits (287), Expect = 1e-25
Identities = 99/423 (23%), Positives = 218/423 (51%), Gaps = 32/423 (7%)
Query: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQ 74
+L+E Q ++ + S+I LE+ L +E Q R+QE V+ Q Q+ E + Q
Sbjct: 1596 DLEERSQELQAQSSQIH--------DLESHSTVLARELQERDQE--VKSQREQIEELQRQ 1645
Query: 75 VRE--QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 132
Q+ + R+QE ++++ QV E + R ++ ++ E++ + + + R +E +
Sbjct: 1646 KEHLTQDLERRDQELMLQKERIQVLEDQ---RTRQTKILEEDLEQIKLSLRERGRELTTQ 1702
Query: 133 EQEGQVREQEGQ--VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190
Q Q R +EG+ + Q G + + +R++E +V Q+ + E + + E Q++
Sbjct: 1703 RQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGL 1762
Query: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
++GE + ++E+++ ++Q+Q+ EQ +E+ ++ Q ++ Q ++ E +
Sbjct: 1763 HRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEAL 1822
Query: 251 QKQEEQMRKQEEQMREQEEQMR---EQEEQMLKQK--EQTEQEEQTGEQEEQMREQEEQM 305
Q++++Q + QEE+++E+ + ++ EQ LK++ E + +EQ EE++ + ++
Sbjct: 1823 QQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRV 1882
Query: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE 365
+ EE + + + REQE+ + ++Q EQ ++ + E Q+ + Q + + K+
Sbjct: 1883 QALEEVLGDLRAESREQEKALLALQQQCAEQAQE--HEVETRALQDSWL--QAQAVLKER 1938
Query: 366 EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMR 425
+Q + E +R + + R QEE R + E + +E +G+ ++ +E+ + EQ E R
Sbjct: 1939 DQ---ELEALRAESQSSRHQEEAARARAEAL---QEALGKAHAALQGKEQHLLEQAELSR 1992
Query: 426 KQE 428
E
Sbjct: 1993 SLE 1995
Score = 111 bits (278), Expect = 1e-24
Identities = 105/485 (21%), Positives = 221/485 (45%), Gaps = 69/485 (14%)
Query: 10 KEKNAELQEE-LQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQV 68
KEK E Q+E + ++ K +++ ++ L RK+ + L Q REQE V +Q+ Q
Sbjct: 1734 KEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQ----REQEIVVLQQQLQE 1789
Query: 69 REQEGQVREQEGQVREQEGQ----VREQEGQVREQEGQVRE-QEGQVREQ----EGQVRE 119
++G+++EQ Q + E Q R+QE + +QE Q + QE +V+E+ +G + +
Sbjct: 1790 AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQ 1849
Query: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 179
++E+ G++++ + Q R E ++ + +V+ E + + + REQE + + Q
Sbjct: 1850 AHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQ 1909
Query: 180 VREQ--EGQV------------------REQEGQMGEQEGQMGEQEEQ------------ 207
EQ E +V R+QE + E Q +E+
Sbjct: 1910 CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEA 1969
Query: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
+G+ +Q +E+ + EQ E R E + + + ++ EE +R QE ++++Q
Sbjct: 1970 LGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQ 2029
Query: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ-- 325
+ + +E +Q+ + Q ++E + ++ EQ+ E+ R QE ++E++ +E+EE+
Sbjct: 2030 DLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEI 2089
Query: 326 -------------MGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ---MQKQEEQVR 369
+ ++E+++ E +E + + EEQ + E +++
Sbjct: 2090 RGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQ 2149
Query: 370 KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE-----QEEQMGEQKEQM 424
++ E+++ Q +E + R++ + + Q ++E Q + EQ
Sbjct: 2150 RELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQ 2209
Query: 425 RKQEE 429
R Q+E
Sbjct: 2210 RLQDE 2214
Score = 101 bits (252), Expect = 1e-21
Identities = 105/471 (22%), Positives = 222/471 (47%), Gaps = 44/471 (9%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
++ +E AELQ +L+ ++ EK EIQ + E + + E L Q Q +++ +V +
Sbjct: 669 QKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARA- 727
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEG-------------QVREQEGQVREQ 113
V+E+E VRE+ + R+++ + +G + ++Q +
Sbjct: 728 -VQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVT 786
Query: 114 EGQVREQEGQVREQ----EGQVR------EQEGQVREQEGQVREQEGQVREQEGQVR-EQ 162
+GQ+ Q V + +G+VR + E EQE ++ EQEG+ EQ
Sbjct: 787 KGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQ 846
Query: 163 EGQVREQE-GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ--EEQMGEQEEQMQKQE 219
+ E+E Q+RE+ + R Q + + E+E E +EQ E E ++E
Sbjct: 847 QKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQRE 906
Query: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE--QEEQMREQEEQ 277
E+ + E + + + + ++ + + Q QK+ +Q E++R+ + ++++EQE
Sbjct: 907 EERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETT 966
Query: 278 MLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ------EE 331
+ Q + E + + E Q R+ ++E+ + + + +++Q E + Q +
Sbjct: 967 GILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ 1026
Query: 332 QMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRK 391
++ EQ+ Q ++ Q + + ++ E+E+ ++Q + ++ + +R+QE +
Sbjct: 1027 RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALR 1086
Query: 392 Q--EEQMGEQKE---QMGEQKEQMREQEEQMGEQKEQMRKQEE--HMGEQK 435
Q +E GEQKE QM +++++E+E Q+ Q+ ++ E H+ EQ+
Sbjct: 1087 QDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQ 1137
Score = 98.2 bits (243), Expect = 1e-20
Identities = 106/467 (22%), Positives = 219/467 (46%), Gaps = 46/467 (9%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E L EKN L+ +LQ E +E+Q +++++ + E + L + +E EQ
Sbjct: 655 EALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLH 714
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Q +++ +V + V+E+E VRE+ + R+++ + +G +E +
Sbjct: 715 QEAKRQEEVLARA--VQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKE-LLES 771
Query: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
+ ++Q + +GQ+ Q V + + + +G+VR + ++ + Q EQE
Sbjct: 772 SLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVI---QGEVRCLKLELDTERSQA-EQERD 827
Query: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE----EQMGEQEEQMRKQEEQMGEQEEQ 242
++ EQEG+ ++++ ++E Q +E E+ Q+E + E E+ E
Sbjct: 828 AAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMEL 887
Query: 243 VQKQEEQVQKQEEQMRKQEEQMREQEE---QMREQEEQ----MLKQKEQTEQE-EQTGEQ 294
+ +EQ + E ++EE+ + E QM+ + E+ +L+ QT++E +Q
Sbjct: 888 EMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQ 947
Query: 295 EEQMRE--QEEQMREQE------EQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ 346
E++R+ + ++++EQE Q++E + +++E Q + E+ + + K
Sbjct: 948 LERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMD 1007
Query: 347 MWKQEEQMGEQ---EEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEE-----QMGE 398
+ KQ E + Q ++ Q+ EQ + +E++R+ +E R Q+E R++ E
Sbjct: 1008 LQKQVEDLKSQLVAQDDSQRLVEQ--EVQEKLRETQEYNRIQKELEREKASLTLSLMEKE 1065
Query: 399 QKEQMGEQKEQMREQE---------EQMGEQKEQMRKQEEHMGEQKE 436
Q+ + ++ + +R+QE E GEQKE + E E KE
Sbjct: 1066 QRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKE 1112
Score = 95.1 bits (235), Expect = 1e-19
Identities = 93/432 (21%), Positives = 202/432 (46%), Gaps = 36/432 (8%)
Query: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
N ++ +L+ ++Q V K IQ ++ LK +L+T++ QE ++ EQE
Sbjct: 780 NSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQE 839
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
G+ + +Q+ ++ Q+RE+ +E+ +E + E + E E +++
Sbjct: 840 GKTA-----LEQQKAAHEKEVNQLREK--WEKERSWHQQELAKALESLEREKMELEMRLK 892
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
EQ+ ++ + Q E+ Q E + + + + ++ + E Q +++ +Q
Sbjct: 893 EQQTEMEAIQAQREEERTQA---ESALCQMQLETEKERVSLLETLLQTQKELADASQQLE 949
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
++R+ + + Q +++E G + Q+Q+ + ++ E Q R + E+ + +
Sbjct: 950 RLRQ------DMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Query: 246 QEEQVQKQEEQMRKQ------EEQMREQE--EQMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
+ +QKQ E ++ Q +++ EQE E++RE +E QKE E+E+ +
Sbjct: 1004 DKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKE-LEREKASLTLSLM 1062
Query: 298 MREQEEQMREQEEQMREQEEQMREQE--EQMGKQEE---QMWEQKEQMWEQKEQMWKQEE 352
+EQ + ++ + +R+QE Q+ E G+Q+E QM ++++ E++ QE
Sbjct: 1063 EKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEA 1122
Query: 353 QMGEQEEQMQKQEEQVR----KQEEQMRKQEEQMRKQEEQMR--KQEEQMGEQKEQMGEQ 406
Q+ E+ E E+Q+R QE + + + ++R E Q+ E+Q G Q + +
Sbjct: 1123 QLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQL 1182
Query: 407 KEQMREQEEQMG 418
++ +G
Sbjct: 1183 ASLYSALQQALG 1194
Score = 88.6 bits (218), Expect = 1e-17
Identities = 84/451 (18%), Positives = 209/451 (46%), Gaps = 39/451 (8%)
Query: 14 AELQEELQLVETEKSEIQ---LHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVRE 70
AEL ++TE ++++ + + L L DK+ L Q+ E+E Q + E
Sbjct: 578 AELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAE 637
Query: 71 QEG---QVREQEGQVREQ---------EGQVREQEGQVREQEGQVREQEGQVREQEGQVR 118
Q QV E + R + E Q+++ E E + +R+ ++E++ +++
Sbjct: 638 QARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRD----IQEEKEEIQ 693
Query: 119 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQEGQVREQE 177
++ + R Q+ Q Q+ ++ + E + V+E+E VRE+ + R+++
Sbjct: 694 KKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQ 753
Query: 178 GQVREQEGQVREQE---GQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE 234
+ +G +E + E + Q E G+ E Q+Q + + ++R +
Sbjct: 754 DLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKL 813
Query: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294
++ + Q +++ + +Q Q ++ + EQ++ E+E L++K + E+ E
Sbjct: 814 ELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQEL 873
Query: 295 EEQMREQEEQMREQEEQMREQEEQMR----EQEEQMGKQEEQMWEQKEQMWEQK----EQ 346
+ + E + E E +++EQ+ +M ++EE+ + E + + + + +++ E
Sbjct: 874 AKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLET 933
Query: 347 MWKQEEQMGEQEEQMQK--QEEQVRKQEEQ------MRKQEEQMRKQEEQMRKQEEQMGE 398
+ + ++++ + +Q+++ Q+ +V+K +EQ + +E R+ +E R+ + +
Sbjct: 934 LLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAA 993
Query: 399 QKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
+E+ + + ++Q+ + K Q+ Q++
Sbjct: 994 LQEESSSLLQDKMDLQKQVEDLKSQLVAQDD 1024
Score = 83.6 bits (205), Expect = 3e-16
Identities = 94/491 (19%), Positives = 214/491 (43%), Gaps = 76/491 (15%)
Query: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQ 74
EL + L+ +E EK E+++ +KE + ++E I +E + + E + + + + ++
Sbjct: 872 ELAKALESLEREKMELEMRLKEQQTEMEA--IQAQREEERTQAESALCQMQLETEKERVS 929
Query: 75 VREQEGQVREQEGQVREQEGQVRE--QEGQVREQEG------QVREQEGQVREQEGQVRE 126
+ E Q +++ +Q ++R+ + +++EQE Q++E + +++E Q R+
Sbjct: 930 LLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRD 989
Query: 127 QEGQVREQEGQVREQ----EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
++E+ + + + QV + + Q+ Q+ R E +V+E+ + +E +E
Sbjct: 990 DLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKE 1049
Query: 183 QEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQM----QKQEEQMGEQEE---QMRKQEEQ 235
E + + E+E ++ +E +++++ Q +E GEQ+E QM ++
Sbjct: 1050 LEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQE 1109
Query: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE----QEEQMREQEEQMLKQKEQTEQ---E 288
+ E+E QE Q+ ++ E E+Q+R QE + + + ++ + Q E E
Sbjct: 1110 VKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAE 1169
Query: 289 EQTGEQEEQMREQEEQMREQEEQMREQEEQMRE--------------QEEQMG------- 327
+Q G Q + + ++ + E E + +Q G
Sbjct: 1170 QQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKR 1229
Query: 328 -----------------KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRK 370
K + +W+ ++ ++Q+ K EE++ + E + + +++
Sbjct: 1230 GPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQD 1289
Query: 371 QEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE----EQMGEQ------ 420
+ Q+ + +E+ K E + E ++ E E M + ++R E E GE+
Sbjct: 1290 LQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAA 1349
Query: 421 KEQMRKQEEHM 431
KE + Q EH+
Sbjct: 1350 KENLTAQVEHL 1360
Score = 79.3 bits (194), Expect = 6e-15
Identities = 82/416 (19%), Positives = 191/416 (45%), Gaps = 40/416 (9%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQV-REQEGQVREQE 65
++ E+ E + E + ++ + Q +KE ++LE L E Q R QE R +
Sbjct: 1908 QQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEA----LRAESQSSRHQEEAARARA 1963
Query: 66 GQVREQEGQ----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
++E G+ ++ +E + EQ R E + + + R+ E +R QE
Sbjct: 1964 EALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQE 2023
Query: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQ 179
G++++Q+ + +E Q+++ Q R++E + +++ Q+ E+ R QE ++E++ GQ
Sbjct: 2024 GEIQDQDLRYQEDVQQLQQALAQ-RDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQ 2082
Query: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQ 239
RE+E ++R + E + + ++E+++ E E Q+ + + EEQ
Sbjct: 2083 EREEE-EIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQ---- 2137
Query: 240 EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
++ E ++Q++ E+++ Q +E + RE+ + + QT+ + ++
Sbjct: 2138 SLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFL 2197
Query: 300 EQEEQMREQEEQMREQEEQMR----EQEE----------QMGKQEEQMWEQKEQMWEQKE 345
+ R+ E+Q + E ++ E+E ++G + EQ + E + E
Sbjct: 2198 QASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAE 2257
Query: 346 --------QMWKQE-EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
Q W+Q E + + +++ ++++ Q+R EQ+ ++ +++++
Sbjct: 2258 PSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKRE 2313
Score = 77.8 bits (190), Expect = 2e-14
Identities = 92/471 (19%), Positives = 194/471 (41%), Gaps = 53/471 (11%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEG------------QV 54
+++K + + QE +++T+ E Q +KE R+ D L +E QV
Sbjct: 953 QDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQV 1012
Query: 55 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV---------REQEGQVRE 105
+ + Q+ Q+ R E +V+E+ + +E +E E + +EQ V +
Sbjct: 1013 EDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQ 1072
Query: 106 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 165
+ +R+QE Q+ Q E +G+ +E Q+ +V+E+E QE Q+ E+
Sbjct: 1073 EADSIRQQELSALRQDMQ--EAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEA 1130
Query: 166 VREQEGQVRE----QEGQVREQEGQVREQEGQMGE--QEGQMGEQEEQMGEQEEQMQKQE 219
E Q+R QE + + + ++R E Q+ E Q G Q + + +
Sbjct: 1131 SHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQ 1190
Query: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
+ +G E R + G+ V E ++ E + ++
Sbjct: 1191 QALGSVCES-RPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLH 1249
Query: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339
+ +T+Q +R+Q +++ E+ ++ Q+ + + + +Q Q E+K +
Sbjct: 1250 QDLWKTQQTRDV------LRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSK 1303
Query: 340 MWEQKEQMWKQE-----EQMGEQEEQMQKQE----------EQVRKQEEQMRKQEEQMRK 384
WE K+ + E E M + ++++ E E ++ +E + Q E ++
Sbjct: 1304 -WEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQA 1362
Query: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
+ R Q G +E + + ++ + E++ ++E+ + +E GE K
Sbjct: 1363 AVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQE-QGELK 1412
Score = 76.3 bits (186), Expect = 5e-14
Identities = 92/462 (19%), Positives = 206/462 (44%), Gaps = 41/462 (8%)
Query: 1 MPRITNEE--LKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQ 57
+ ++T E L + +LQ E+ + E+ +Q +EL+++LE L QE ++R
Sbjct: 437 LQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV----LEQEAWRLRRV 492
Query: 58 EGQVREQ----EGQVREQEGQ----VREQEGQVREQEGQVREQEGQVRE-----QEGQVR 104
+++ Q +GQ EQ+ + VRE+E G +Q + E + +
Sbjct: 493 NVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESS 552
Query: 105 EQEGQV-REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 163
EG++ R+++ +V + + ++ E ++ + +R ++ + +
Sbjct: 553 HLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDK 612
Query: 164 GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ----EEQMQKQE 219
+ +Q Q+ E+ V + + + + ++ E + E+ E Q+QK E
Sbjct: 613 VGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAE 672
Query: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
E E + +R + E++E++QK+ + + Q+E Q EQ+ ++ ++ E + +
Sbjct: 673 EAGAELQADLR----DIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAV 728
Query: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339
++KE +E+ E Q E++ Q + EQ + + +E + + +Q
Sbjct: 729 QEKEALVREKAALEVRLQAVERDRQ------DLAEQLQGLSSAKELLESSLFEAQQQNSV 782
Query: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG-- 397
+ K Q+ Q + + + +E +Q + ++ + + R Q EQ R + Q EQ G
Sbjct: 783 IEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKT 842
Query: 398 ---EQKEQMGEQKEQMREQ-EEQMGEQKEQMRKQEEHMGEQK 435
+QK ++ Q+RE+ E++ ++++ K E + +K
Sbjct: 843 ALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREK 884
Score = 73.6 bits (179), Expect = 3e-13
Identities = 93/498 (18%), Positives = 218/498 (43%), Gaps = 73/498 (14%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E L++ EL+++L+++E E ++ EL+ L+ D +E Q E VRE+E
Sbjct: 466 ELLQKAREELRQQLEVLEQEAWRLRRVNVELQ--LQGDSAQGQKEEQQEELHLAVRERER 523
Query: 67 QVREQEGQVREQEGQVRE-----QEGQVREQEGQV-REQEGQVREQEGQVREQEGQVREQ 120
G +Q + E + + EG++ R+++ +V + + ++
Sbjct: 524 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSS 583
Query: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
E ++ + +R ++ + + + +Q Q+ E+ V + + +
Sbjct: 584 ENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNAL 643
Query: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
+ + ++ + E+ + Q ++ E ++Q + E++E+++K+ + Q+
Sbjct: 644 QVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQ 703
Query: 241 E----QVQKQEEQVQKQEE----QMRKQEEQMREQ-------------EEQMREQEEQML 279
E Q+++ ++ ++QEE ++++E +RE+ + + EQ + +
Sbjct: 704 EAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLS 763
Query: 280 KQKE---------------------QTEQEEQTGEQEEQMREQE--------EQMREQEE 310
KE Q E + QT Q +++ + E + R Q E
Sbjct: 764 SAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAE 823
Query: 311 QMREQEEQMREQEEQMGK---QEEQMWEQKE-----QMWEQKEQMWKQEEQMGEQEE-QM 361
Q R+ + Q EQ GK ++++ +KE + WE KE+ W Q+E E +
Sbjct: 824 QERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWE-KERSWHQQELAKALESLER 882
Query: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ----EEQMGEQKEQMGEQKEQMREQEEQM 417
+K E ++R +E+Q + Q +++EE+ + + + Q+ +KE++ E + + ++++
Sbjct: 883 EKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERV-SLLETLLQTQKEL 941
Query: 418 GEQKEQMRKQEEHMGEQK 435
+ +Q+ + + M QK
Sbjct: 942 ADASQQLERLRQDMKVQK 959
Score = 73.2 bits (178), Expect = 4e-13
Identities = 89/480 (18%), Positives = 197/480 (41%), Gaps = 61/480 (12%)
Query: 5 TNEELKEKNAELQEELQLV---ETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61
T E KE + QE +QL + EK+E+Q + EL L Q ++Q
Sbjct: 253 TQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLT----------QSQKQNEDY 302
Query: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQ 120
+ +RE + ++ E E + + + QV + QV +EG + +
Sbjct: 303 EKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQG 362
Query: 121 EGQVREQE------GQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEGQVREQ 169
G E Q Q+ VR + R+ +R+Q +E +++Q
Sbjct: 363 SGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQ 422
Query: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229
Q E+ +R++ ++ + + Q + + + + ++ E +QK E++ +Q E +
Sbjct: 423 HDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVL 482
Query: 230 RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE--------QEEQM--- 278
++ ++ ++Q Q + Q Q+E+ +++ + E+++E Q E +
Sbjct: 483 EQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSEL 542
Query: 279 ---------------LKQKEQTEQEEQTGEQEEQMRE---QEEQMREQEEQMREQEEQMR 320
L ++EQTE E+ + E E ++ + +R ++
Sbjct: 543 ITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLS 602
Query: 321 EQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ-- 378
E + + + +Q Q+ E+ + + + E + +Q + K+ E + ++
Sbjct: 603 ALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNT 662
Query: 379 --EEQMRKQEE---QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
E Q++K EE +++ + E+KE++ ++ + R Q+E Q EQ+ ++ + E
Sbjct: 663 HLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEE 722
Score = 70.5 bits (171), Expect = 3e-12
Identities = 97/510 (19%), Positives = 221/510 (43%), Gaps = 85/510 (16%)
Query: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
NE+ ++ L+E ++++ET +E+ H L R + +K+ L Q V + QV +E
Sbjct: 299 NEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQ---VIKDITQVMVEE 355
Query: 66 GQ-VREQEGQVREQE------GQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQ 113
G + + G E Q Q+ VR + R+ +R+Q +E
Sbjct: 356 GDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEA 415
Query: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE--QEGQVREQEG 171
+++Q Q E+EG+ Q ++++ G+ GQ + +G+V +E ++ ++
Sbjct: 416 VNLLQQQHDQW-EEEGKALRQ--RLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAR 472
Query: 172 QVREQEGQVREQEG-QVR----EQEGQMGEQEGQMGEQEEQMG---EQEEQMQ------- 216
+ Q+ +V EQE ++R E + Q +GQ EQ+E++ + E++Q
Sbjct: 473 EELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLE 532
Query: 217 -KQEEQMGE-------------QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE 262
KQ E + E + E +R+++ ++ + ++ ++ E ++ +
Sbjct: 533 AKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVA 592
Query: 263 QMR---------------------EQEEQMREQEEQMLKQKEQTEQEEQTGE----QEEQ 297
+R +Q Q+ E+ + + + E EQ + + E+
Sbjct: 593 DLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEK 652
Query: 298 MREQ--------EEQMREQEEQMREQEEQMR---EQEEQMGKQEEQMWEQKEQMWEQKEQ 346
RE E Q+++ EE E + +R E++E++ K+ + Q+E Q EQ
Sbjct: 653 RREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQ 712
Query: 347 MWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ 406
+ ++ ++ E + +++E + +++ + + + + + + + +Q + + KE +
Sbjct: 713 LHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESS 772
Query: 407 KEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+ ++Q + K Q+ Q + + + KE
Sbjct: 773 LFEAQQQNSVIEVTKGQLEVQIQTVTQAKE 802
Score = 62.8 bits (151), Expect = 6e-10
Identities = 53/314 (16%), Positives = 141/314 (44%), Gaps = 28/314 (8%)
Query: 144 QVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQ 200
Q RE G R + Q+ + +E E + E+ ++ + + Q ++ ++ ++ +
Sbjct: 228 QSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTE 287
Query: 201 MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQ 260
+ Q +Q E +K + + E E + ++ E E + + ++ + +Q+ K
Sbjct: 288 LSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKD 347
Query: 261 EEQMREQE----------EQMREQEEQMLKQKEQTEQEE----------QTGEQEEQMRE 300
Q+ +E E E + + Q + + ++ + + + +R+
Sbjct: 348 ITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQ 407
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Q +E +++Q +Q E+ + + ++ +++ +++ + Q + + + + ++ E
Sbjct: 408 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKEREL 467
Query: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ-----KEQMREQEE 415
+QK E++R+Q E + ++ ++R+ +++ Q + QKE+ E+ +E+ R QE
Sbjct: 468 LQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEM 527
Query: 416 QMGEQKEQMRKQEE 429
MG + +Q E
Sbjct: 528 LMGLEAKQSESLSE 541
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/303 (16%), Positives = 134/303 (44%), Gaps = 21/303 (6%)
Query: 151 QVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ 207
Q RE G R + Q+ + +E E + E+ ++ + + Q ++ ++ ++ +
Sbjct: 228 QSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTE 287
Query: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
+ Q QKQ E + + +R+ E + ++ + E + + ++ + +Q+ +
Sbjct: 288 LSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKD 347
Query: 268 EEQMREQEEQMLKQKEQTEQE-------------EQTGEQEEQMREQEEQMREQEEQMRE 314
Q+ +E + Q E + + +R + R+ + +R+
Sbjct: 348 ITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQ 407
Query: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
Q +E + +Q +Q E+ + + ++ +++ + + + Q +Q + + + K+ E
Sbjct: 408 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKEREL 467
Query: 375 MRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ-----KEQMRKQEE 429
++K E++R+Q E + ++ ++ ++ Q + + Q+E+ E+ +E+ R QE
Sbjct: 468 LQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEM 527
Query: 430 HMG 432
MG
Sbjct: 528 LMG 530
Score = 48.9 bits (115), Expect = 9e-06
Identities = 67/342 (19%), Positives = 146/342 (42%), Gaps = 63/342 (18%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQ 67
E E + L+ ++ Q H ++L+ L QEG++++Q+ + +E Q
Sbjct: 1986 EQAELSRSLEASTATLQASLDACQAHSRQLEEALRI------QEGEIQDQDLRYQEDVQQ 2039
Query: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVR 125
+++ Q R++E + +++ Q+ E+ R QE ++E++ GQ RE+E ++R VR
Sbjct: 2040 LQQALAQ-RDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEE-EIRGLHQSVR 2097
Query: 126 EQEGQVREQEGQVRE-QEGQVRE---------QEGQVREQEGQVREQEGQVREQEGQVRE 175
E + + ++E ++ E +E Q R + + EQ ++ E +++ + +++
Sbjct: 2098 ELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQA 2157
Query: 176 QEGQVREQEGQVREQEGQMGE------------QEGQMGEQEEQMGEQEEQMQKQEE--- 220
Q +E + RE+ + QE M Q + EQ + Q+E
Sbjct: 2158 ALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELEL 2217
Query: 221 -------------------QMGEQEEQMRKQEEQMGEQEEQ----VQKQE-----EQVQK 252
++G + EQ + E G + E ++KQ E +Q+
Sbjct: 2218 TRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQ 2277
Query: 253 QEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294
++ +++ Q+R EQ+ +++ + ++E Q
Sbjct: 2278 AVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQ 2319
Score = 37.0 bits (84), Expect = 0.035
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 25/191 (13%)
Query: 229 MRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ---MREQEEQMLKQK--- 282
M+ Q Q+ +E+ + Q++ + Q RK + Q+ Q +R+ + ++L+ +
Sbjct: 11 MKPQSLQLVLEEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQYRSWC 70
Query: 283 -EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
E ++ E TG Q E E+ E +R +EEQ R E +
Sbjct: 71 QELEKRLEATGGPIPQRWENVEEPNLDELLVRLEEEQQR----------------CESLA 114
Query: 342 EQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
E Q+ E+ + +++ E++ + R ++E MRK+ + +QE G K
Sbjct: 115 EVNTQLRLHMEKADVVNKALREDVEKLTV--DWSRARDELMRKESQWQMEQEFFKGYLKG 172
Query: 402 QMGEQKEQMRE 412
+ G RE
Sbjct: 173 EHGRLLSLWRE 183
Score = 36.6 bits (83), Expect = 0.046
Identities = 31/144 (21%), Positives = 69/144 (47%), Gaps = 18/144 (12%)
Query: 212 EEQMQKQEEQMGEQE----EQMRKQEEQMGEQEEQVQKQEEQV-------QKQEEQMRKQ 260
EEQ+ ++QM E + +++ +E Q V+K + +V Q+ E+++
Sbjct: 21 EEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEAT 80
Query: 261 EEQMREQEEQMREQ--EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318
+ ++ E + E +E +++ +E+ ++ E E Q+R E+ + +RE E+
Sbjct: 81 GGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEK 140
Query: 319 M-----REQEEQMGKQEEQMWEQK 337
+ R ++E M K+ + EQ+
Sbjct: 141 LTVDWSRARDELMRKESQWQMEQE 164
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQM 389
EEQ+ ++QM E + W+ ++ +E Q+Q VRK + ++ Q R +++
Sbjct: 21 EEQVLALQQQMAENQAASWR---KLKNSQEAQQRQATLVRKLQAKVL----QYRSWCQEL 73
Query: 390 RKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMR 425
K+ E G Q E E+ E + ++EQ R
Sbjct: 74 EKRLEATGGPIPQRWENVEEPNLDELLVRLEEEQQR 109
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 122 bits (306), Expect = 6e-28
Identities = 88/437 (20%), Positives = 208/437 (47%), Gaps = 21/437 (4%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLH--IKELK-RKLETDKIPLPQEGQVREQEGQVRE 63
+++++ EL+E+L+ E+ + ++QL E K +KLE ++I L + +E ++ E
Sbjct: 939 KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
Query: 64 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 123
++ E + E+E + + + E + + E ++R +E Q +E E R+ EG
Sbjct: 999 D--RIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1056
Query: 124 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
+ Q+ E + Q+ E + Q+ ++E +++ +V E+ Q ++RE E Q+ E
Sbjct: 1057 STDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISEL 1116
Query: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG----EQ 239
+ + + + E Q + E++ + +++ + Q+E K+E+++
Sbjct: 1117 QEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTL 1176
Query: 240 EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE----------- 288
EE+ + E Q+Q+ ++ + E++ EQ EQ + + + K K+ E E
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 289 -EQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM 347
+ G+ E + ++ E Q++E + + E E E +++ K + ++ + + +
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKS 1296
Query: 348 WKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQK 407
K + E Q+Q +E ++++ Q ++++ E++ EQ+ E++E +
Sbjct: 1297 SKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE 1356
Query: 408 EQMREQEEQMGEQKEQM 424
+Q+ Q+ + K++M
Sbjct: 1357 KQIATLHAQVADMKKKM 1373
Score = 119 bits (298), Expect = 5e-27
Identities = 84/453 (18%), Positives = 216/453 (47%), Gaps = 24/453 (5%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQLHIKEL----------KRKLETDKIPLPQEGQVREQ 57
+L+ + E +E Q ++ EK ++Q +I+EL ++KL+ +K+ + + E+
Sbjct: 919 DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978
Query: 58 EGQVREQEG-----QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 112
E + E + + + E ++ E + E+E + + + E + + E ++R
Sbjct: 979 EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR 1038
Query: 113 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 172
+E Q +E E R+ EG + Q+ E + Q+ E + Q+ ++E +++ +V E+ Q
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ 1098
Query: 173 VREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ 232
++RE E Q+ E + + + + E+Q + E+++ + ++ + + Q
Sbjct: 1099 KNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQ 1158
Query: 233 EEQMGEQEEQV----QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE 288
+E ++E++V + EE+ + E Q+++ ++ + E++ EQ EQ + K E+
Sbjct: 1159 QELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKA 1218
Query: 289 EQT-----GEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
+QT GE +++ + + E + ++ E Q++E + + + E E +++ +
Sbjct: 1219 KQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKL 1278
Query: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM 403
+ ++ + + + + K + E Q++ +E ++++ Q ++ + +++
Sbjct: 1279 QVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEK 1338
Query: 404 GEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
+EQ+ E+EE ++Q+ + + K+
Sbjct: 1339 NSFREQLEEEEEAKHNLEKQIATLHAQVADMKK 1371
Score = 112 bits (281), Expect = 5e-25
Identities = 83/445 (18%), Positives = 210/445 (47%), Gaps = 19/445 (4%)
Query: 8 ELKEKNAELQEELQLVETE--KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
+L + +LQE+LQ ETE +L + +K E ++I E +V E+E + + +
Sbjct: 877 QLMAEKLQLQEQLQ-AETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQ 935
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
+ ++ + ++E E Q+ E+E ++ + + E ++++ E + E Q + + +
Sbjct: 936 AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKK 995
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
E ++ E + E+E + + + E + + E ++R +E Q +E E R+ EG
Sbjct: 996 LLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEG 1055
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
+ Q+ E + Q+ E + Q+ ++EE++Q ++ E+ Q +++ E E Q+ +
Sbjct: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISE 1115
Query: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ-----MRE 300
+E ++ + K E+Q R+ E++ + ++ + T +++ + EQ +
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKT 1175
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQM------ 354
EE+ + E Q++E ++ + E++ +Q EQ K + + K+ + + ++
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Query: 355 -----GEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQ 409
G+ E + +K E Q+++ + + + E + +++ K + ++ + + +
Sbjct: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
Query: 410 MREQEEQMGEQKEQMRKQEEHMGEQ 434
+ + + Q++ +E + E+
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEE 1320
Score = 107 bits (266), Expect = 3e-23
Identities = 80/407 (19%), Positives = 197/407 (48%), Gaps = 15/407 (3%)
Query: 40 KLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 99
+L T PL Q + E+ E+ +VRE++ + ++ + Q+ ++ Q++EQ
Sbjct: 829 RLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQ 888
Query: 100 EGQVREQEGQVREQEGQVREQEGQVRE----QEGQVREQEGQVREQEGQVREQEGQVREQ 155
E + E ++ ++ ++ E E +V E+E + + + + ++ + ++E
Sbjct: 889 LQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQEL 948
Query: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQM 215
E Q+ E+E ++ + + E ++++ E + E Q + + E+++ E +
Sbjct: 949 EEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNL 1008
Query: 216 QKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE-------EQMREQE 268
++EE+ + K E + + EE+++++E+Q Q+ E+ RK E +Q+ E +
Sbjct: 1009 TEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQ 1068
Query: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE-EQMREQEEQMREQEEQMREQEEQMG 327
Q+ E + Q+ K++E+ + E+E + +++RE E Q+ E +E + +
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRN 1128
Query: 328 KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
K E+Q + E++ K ++ + Q+E K+E++V ++ + EE+ + E
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTL---EEEAKTHEA 1185
Query: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQ 434
Q+++ ++ + E++ EQ EQ + + + + K+ + + + +
Sbjct: 1186 QIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Score = 105 bits (261), Expect = 1e-22
Identities = 86/439 (19%), Positives = 203/439 (46%), Gaps = 19/439 (4%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQ-VREQEGQVREQEG 66
E + K L L+ +K+E++ K+ + ++E G+ V E E R E
Sbjct: 1473 EKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV-REQEGQVREQEGQVREQEGQVR 125
QV E + Q+ E E +++ E E ++ + Q R+ +G+ + E + ++ QVR
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1592
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
E E ++ ++ Q ++ E +++ E + E Q+R+ + Q+++
Sbjct: 1593 EMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1652
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
++ + E Q E E+++ E +M + +E++ E R+ +++ E +++
Sbjct: 1653 ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIAN 1712
Query: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQE-------EQMLKQKEQTEQEEQTGEQEEQM 298
+ E+ R+ E ++ + EE++ E++ +++ K Q +Q E
Sbjct: 1713 SSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSH 1772
Query: 299 REQEEQMREQ-EEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357
++ E R+Q E Q +E + +++E E + + K + + ++ + EEQ+ +
Sbjct: 1773 AQKNENARQQLERQNKELKVKLQEMEGTVKSK------YKASITALEAKIAQLEEQLDNE 1826
Query: 358 EEQMQKQEEQVRKQEEQMRK---QEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE 414
++ Q +QVR+ E++++ Q + R+ EQ + Q ++ + +Q+ Q E+ E+
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
Query: 415 EQMGEQKEQMRKQEEHMGE 433
++ + +++++ E E
Sbjct: 1887 QRANASRRKLQRELEDATE 1905
Score = 103 bits (258), Expect = 2e-22
Identities = 87/472 (18%), Positives = 214/472 (45%), Gaps = 45/472 (9%)
Query: 9 LKEKNAELQEELQLVETEKSEIQLHIKELKRKLET-DKIPLPQEGQVREQEGQVREQEGQ 67
L+++N +L +E +L+E +E ++ E + K ++ K+ E + + E ++R +E Q
Sbjct: 983 LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQ 1042
Query: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
+E E R+ EG + Q+ E + Q+ E + Q+ ++E +++ +V E+ Q
Sbjct: 1043 RQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMA 1102
Query: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV--------------------- 166
++RE E Q+ E + + + + E Q R+ ++
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 167 --REQEGQVREQ--EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ---- 218
REQE + ++ E + + E Q++E + + ++ EQ EQ + ++K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
E + GE +++ + G+ E + +K E Q+Q+ + + + E E +++ + + ++
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 279 ------LKQ---------KEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
L Q K+ + E Q + +E ++E+ Q ++++ E++
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 324 EQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMR 383
EQ+ ++EE ++Q+ Q+ +++M + ++ EE RK ++ + ++
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHE 1402
Query: 384 KQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
++ K E+ ++++ + + Q + +++ +K ++ + E+K
Sbjct: 1403 EKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454
Score = 101 bits (251), Expect = 2e-21
Identities = 67/397 (16%), Positives = 186/397 (46%), Gaps = 10/397 (2%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
EE+K + EL++ELQ E K ++++++ +K + E D +G+ + E + ++
Sbjct: 1535 EEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL-----QGRDEQSEEKKKQLVR 1589
Query: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
QVRE E ++ ++ Q ++ E +++ E + E Q+R+ + Q+++
Sbjct: 1590 QVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKD 1649
Query: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
++ + E Q +E E +++ E ++ + + ++ E R+ + + E +
Sbjct: 1650 CMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE 1709
Query: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
+ G+ + E ++ + EE++++++ ++++K Q+ + + +
Sbjct: 1710 IANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE 1769
Query: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
QK E ++ E Q +E + +++E E + +++ + E ++ + EEQ+
Sbjct: 1770 RSHAQKNENARQQLERQNKELKVKLQEMEGTV-----KSKYKASITALEAKIAQLEEQLD 1824
Query: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
+ ++ + +Q+R E+++ Q+ +++ + K+Q K ++ + + Q+++ EE
Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884
Query: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM 403
+ ++ RK + ++ E ++ K ++
Sbjct: 1885 EAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 100 bits (248), Expect = 3e-21
Identities = 72/338 (21%), Positives = 170/338 (50%), Gaps = 11/338 (3%)
Query: 104 REQEGQVREQE-GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 162
+E+E +E+E +VRE++ + ++ + Q+ ++ Q++EQ E + E
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 163 EGQVREQEGQVRE----QEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ 218
++ ++ ++ E E +V E+E + + + + + + + E EEQ+ E+E QK
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
+ + E +++K EE+ E+Q K ++ + E+++ + + E+EE+ + +
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK-- 1020
Query: 279 LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKE 338
LK K E + EE++R +E+Q +E E+ R+ E + +Q+ + + Q+ E K
Sbjct: 1021 LKNKH----EAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM 1076
Query: 339 QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Q+ +++E++ ++ E+ Q +++R+ E Q+ + +E + + K E+Q +
Sbjct: 1077 QLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRD 1136
Query: 399 QKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
E++ K ++ + + Q+E K+E+ + K+
Sbjct: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKK 1174
Score = 93.6 bits (231), Expect = 3e-19
Identities = 78/454 (17%), Positives = 211/454 (46%), Gaps = 41/454 (9%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQ 67
EL+ + +ELQE+L+ +++ + ++L +LE K L + ++R +
Sbjct: 1108 ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK--- 1164
Query: 68 VREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
REQE + ++ E + + E Q++E +R++ Q E+ + EQ Q + + +
Sbjct: 1165 -REQEVNILKKTLEEEAKTHEAQIQE----MRQKHSQAVEE---LAEQLEQTKRVKANLE 1216
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
+ + + + G++ + + + +G + E + ++ E Q++E + + E E E
Sbjct: 1217 KAKQTLENERGELANEVKVLLQGKG---DSEHKRKKVEAQLQELQVKFNEGERVRTELAD 1273
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
+V + + ++ G + + + + + + E Q+ + +E ++++ Q ++++
Sbjct: 1274 KVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333
Query: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305
E++ EQ+ ++EE E+Q+ Q+ K++ E E E+++ + ++
Sbjct: 1334 VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKD 1393
Query: 306 REQEEQMREQEEQMREQEEQMGKQEEQ--------MWEQKEQMWEQKEQMWKQEEQMGEQ 357
E Q E++ ++ E+ + +Q + Q++ +++ K ++ + E+
Sbjct: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453
Query: 358 E-------EQMQKQEEQVRKQE----------EQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
+ E+ + E + R++E E+ +Q+ ++ + +Q R + E + K
Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513
Query: 401 EQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQ 434
+ +G+ ++ + + + +Q E+M+ Q E + ++
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDE 1547
Score = 93.2 bits (230), Expect = 4e-19
Identities = 90/444 (20%), Positives = 199/444 (44%), Gaps = 23/444 (5%)
Query: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQ 67
E K +A+ EE E E E + L R LE + Q+ ++ Q R +
Sbjct: 1452 EEKTISAKYAEERDRAEAEAREKETKALSLARALEE---AMEQKAELERLNKQFRTEMED 1508
Query: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
+ + V + V E E R E QV E + Q+ E E +++ E E ++
Sbjct: 1509 LMSSKDDVGKS---VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAM 1565
Query: 128 EGQV-REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
+ Q R+ +G+ + E + ++ QVRE E ++ ++ Q ++ E +++ E
Sbjct: 1566 KAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAH 1625
Query: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE-EQVQK 245
+ E Q+ + + QM + ++ E Q ++ E+++ E E +Q
Sbjct: 1626 IDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQL 1685
Query: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE--- 302
QEE + + + Q+E+ +E + L +E+ E + + EE++ E++
Sbjct: 1686 QEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNT 1745
Query: 303 EQMREQEEQMREQEEQMREQ---EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEE 359
E + ++ ++ Q +Q+ E ++ E +Q E+ + KE K +E G +
Sbjct: 1746 ELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER--QNKELKVKLQEMEGTVKS 1803
Query: 360 QMQKQ----EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQK---EQMRE 412
+ + E ++ + EEQ+ + ++ + +Q+R+ E+++ + Q+ +++ EQ ++
Sbjct: 1804 KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKD 1863
Query: 413 QEEQMGEQKEQMRKQEEHMGEQKE 436
Q ++ + +Q+++Q E E+ +
Sbjct: 1864 QADKASTRLKQLKRQLEEAEEEAQ 1887
Score = 91.7 bits (226), Expect = 1e-18
Identities = 68/435 (15%), Positives = 195/435 (44%), Gaps = 11/435 (2%)
Query: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLE--------TDKIPLPQEGQV 54
R E+L ++ + + +E K ++ ++E+K +LE T+ L E +
Sbjct: 1503 RTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL 1562
Query: 55 REQEGQV-REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 113
+ + Q R+ +G+ + E + ++ QVRE E ++ ++ Q ++ E +++
Sbjct: 1563 QAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDL 1622
Query: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 173
E + E Q+R+ + Q+++ ++ + E Q +E E +++ E ++
Sbjct: 1623 EAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
Query: 174 REQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE 233
+ + ++ E R+ + + E ++ + E+ ++ E ++ + EE++ +++
Sbjct: 1683 IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1742
Query: 234 EQMGEQEEQVQKQEEQVQK--QEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQT 291
++++K Q+ + + + + Q E Q E++ + LK K Q +
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
Query: 292 GEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
+ + + E ++ + EEQ+ + ++ + +Q+ + E+++ + Q+ +++ + +
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862
Query: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
+Q + ++++ + Q+ + EE+ ++ RK + ++ E ++ K ++R
Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Query: 412 EQEEQMGEQKEQMRK 426
+ + RK
Sbjct: 1923 RGDLPFVVPRRMARK 1937
Score = 87.8 bits (216), Expect = 2e-17
Identities = 91/487 (18%), Positives = 206/487 (42%), Gaps = 65/487 (13%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKR-KLETDKIPLPQEGQVREQEGQVREQE 65
E+ K A L++ Q +E E+ E+ +K L + K +++ E Q++E + + E E
Sbjct: 1206 EQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGE 1265
Query: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
E +V + + ++ G + + + + + E Q+++ + ++E+ Q
Sbjct: 1266 RVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKL 1325
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
++++ E + Q+ E+E E Q+ QV + + ++ + G + E
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEE-----------------QMQKQEEQMGEQEEQ 228
R+ + + EG EE++ ++ + Q + E++
Sbjct: 1386 VKRKLQKDL---EGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 229 MRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM----REQEEQMREQEE-QMLKQKE 283
+K ++ + E++ K E+ + E + R++E + R EE M ++ E + L ++
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQF 1502
Query: 284 QTEQEEQTGEQEE---QMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
+TE E+ +++ + E E+ R E+Q+ E + Q+ E E+++ E+ + +
Sbjct: 1503 RTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL 1562
Query: 341 WEQKEQMWKQEEQMGEQEEQMQKQ-EEQVRKQEEQM---RKQE----------------- 379
K Q + + EQ E+ +KQ QVR+ E ++ RKQ
Sbjct: 1563 QAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDL 1622
Query: 380 ---------------EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQM 424
+Q+RK + QM+ ++ + + E Q +E E+++ + +M
Sbjct: 1623 EAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
Query: 425 RKQEEHM 431
+ +E +
Sbjct: 1683 IQLQEEL 1689
Score = 82.4 bits (202), Expect = 7e-16
Identities = 75/428 (17%), Positives = 203/428 (47%), Gaps = 27/428 (6%)
Query: 12 KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQE-GQVREQEGQVREQEGQVRE 70
K+++L ++ +E++ + Q ++E R+ K+ L + QV +++ REQ + E
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQ----KLSLSTKLKQVEDEKNSFREQ---LEE 1347
Query: 71 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 130
+E E Q+ QV + + ++ + G + E R+ + ++ EG + E +
Sbjct: 1348 EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQ---KDLEGLSQRHEEK 1404
Query: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVR 188
V + + + +E + + + + Q + ++Q+ Q+ +E + + + R
Sbjct: 1405 VAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEER 1464
Query: 189 EQ-EGQMGEQEGQ---MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
++ E + E+E + + E+ EQ+ ++++ +Q + E + ++ +G+ +++
Sbjct: 1465 DRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524
Query: 245 KQEEQVQKQEEQMRKQEEQMREQ----EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
K + +++Q E+M+ Q E++ ++ E+ E + K Q E++ Q ++EQ E
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG--RDEQSEE 1582
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
+++Q+ Q +M + E R+Q +++ + + + K ++ +Q +
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 361 MQKQEEQVRKQEEQMRKQEE----QMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQ 416
+Q Q + ++ + R E Q ++ E++++ E +M + +E++ + R+ +++
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQE 1702
Query: 417 MGEQKEQM 424
E +++
Sbjct: 1703 RDELADEI 1710
Score = 81.6 bits (200), Expect = 1e-15
Identities = 76/414 (18%), Positives = 181/414 (43%), Gaps = 16/414 (3%)
Query: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
E L +++ E +E K+ +Q + +L L+ + + +++ Q+ +E
Sbjct: 1395 EGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454
Query: 67 QVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
+ + + R++ E + RE+E + + E EQ+ ++ Q R + +
Sbjct: 1455 TISAKYAEERDRAEAEAREKETKALSLARALEE----AMEQKAELERLNKQFRTEMEDLM 1510
Query: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
+ V + V E E R E QV E + Q+ E E +++ E E ++ +
Sbjct: 1511 SSKDDVGKS---VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKA 1567
Query: 186 QV-REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Q R+ +G+ + E + + Q+ E E +++ + +Q +K E + + E +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 245 KQEEQVQKQEEQMRKQEEQM----REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
+ + +Q+RK + QM RE ++ +EE + + K E E++ E +M +
Sbjct: 1628 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK---ENEKKLKSMEAEMIQ 1684
Query: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
+E++ E R+ +++ E +++ + E+ + ++ + EE++ E++
Sbjct: 1685 LQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGN 1744
Query: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE 414
+ ++++K Q+ + + + +K E + + Q E K +++E E
Sbjct: 1745 TELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEME 1798
Score = 55.5 bits (132), Expect = 1e-07
Identities = 34/178 (19%), Positives = 86/178 (48%)
Query: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311
K+++Q+ + R ++ + Q + + + Q QEE+M +EE++ + E+
Sbjct: 801 KRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREK 860
Query: 312 MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ 371
E ++ E E + + + +EQ+ + E + EE + Q+ EE
Sbjct: 861 QLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDL 920
Query: 372 EEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
E ++ ++EE+ + + + +K ++ + E +EQ+ E++ ++ + + + +++K EE
Sbjct: 921 EARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/112 (20%), Positives = 60/112 (53%)
Query: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384
Q+ +QEE+M ++E++ + +E+ E ++ E E + + + +EQ++ + E +
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
EE + + E +E + + ++ E+EE+ + + +K ++++ E +E
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEE 950
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.296 0.116 0.285
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,799,219
Number of Sequences: 37866
Number of extensions: 1330739
Number of successful extensions: 202280
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2347
Number of HSP's successfully gapped in prelim test: 911
Number of HSP's that attempted gapping in prelim test: 10267
Number of HSP's gapped (non-prelim): 48195
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.