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Search of human proteins with 167830433
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform
1 [Homo sapiens]
(1008 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 2041 0.0
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 2003 0.0
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 614 e-175
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 579 e-165
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 508 e-143
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 496 e-140
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 496 e-140
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 348 1e-95
gi|38505213 YTH domain containing 2 [Homo sapiens] 334 2e-91
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 315 2e-85
gi|166851804 tudor domain containing 9 [Homo sapiens] 299 8e-81
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 295 1e-79
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 287 3e-77
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 281 2e-75
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 235 1e-61
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 214 4e-55
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 208 2e-53
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 194 4e-49
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 167 6e-41
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 141 3e-33
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 119 1e-26
gi|12056465 fibrillarin [Homo sapiens] 63 2e-09
gi|109452587 family with sequence similarity 98, member B isofor... 59 2e-08
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 58 5e-08
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 58 5e-08
gi|55956899 keratin 9 [Homo sapiens] 56 1e-07
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 55 3e-07
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 55 3e-07
gi|195972866 keratin 10 [Homo sapiens] 55 4e-07
gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo ... 54 1e-06
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 2041 bits (5288), Expect = 0.0
Identities = 1008/1008 (100%), Positives = 1008/1008 (100%)
Query: 1 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR 60
MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR
Sbjct: 1 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR 60
Query: 61 EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE 120
EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE
Sbjct: 61 EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE 120
Query: 121 DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL 180
DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL
Sbjct: 121 DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL 180
Query: 181 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV 240
DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV
Sbjct: 181 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV 240
Query: 241 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL 300
TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL
Sbjct: 241 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL 300
Query: 301 PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL 360
PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL
Sbjct: 301 PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL 360
Query: 361 KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKR 420
KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKR
Sbjct: 361 KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKR 420
Query: 421 GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR 480
GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR
Sbjct: 421 GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR 480
Query: 481 YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRT 540
YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRT
Sbjct: 481 YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRT 540
Query: 541 PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRK 600
PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRK
Sbjct: 541 PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRK 600
Query: 601 GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD 660
GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD
Sbjct: 601 GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD 660
Query: 661 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT 720
PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT
Sbjct: 661 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT 720
Query: 721 IAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDY 780
IAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDY
Sbjct: 721 IAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDY 780
Query: 781 CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY 840
CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY
Sbjct: 781 CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY 840
Query: 841 PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 900
PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY
Sbjct: 841 PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 900
Query: 901 DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK 960
DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK
Sbjct: 901 DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK 960
Query: 961 IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS 1008
IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS
Sbjct: 961 IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS 1008
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 2003 bits (5190), Expect = 0.0
Identities = 994/1008 (98%), Positives = 994/1008 (98%), Gaps = 14/1008 (1%)
Query: 1 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR 60
MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR
Sbjct: 1 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR 60
Query: 61 EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE 120
EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE
Sbjct: 61 EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE 120
Query: 121 DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL 180
DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL
Sbjct: 121 DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL 180
Query: 181 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV 240
DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV
Sbjct: 181 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV 240
Query: 241 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL 300
TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL
Sbjct: 241 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL 300
Query: 301 PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL 360
PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL
Sbjct: 301 PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL 360
Query: 361 KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKR 420
KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKR
Sbjct: 361 KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKR 420
Query: 421 GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR 480
GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR
Sbjct: 421 GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR 480
Query: 481 YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRT 540
YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKS VNQTQVFKRT
Sbjct: 481 YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKS--------------VNQTQVFKRT 526
Query: 541 PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRK 600
PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRK
Sbjct: 527 PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRK 586
Query: 601 GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD 660
GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD
Sbjct: 587 GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD 646
Query: 661 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT 720
PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT
Sbjct: 647 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT 706
Query: 721 IAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDY 780
IAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDY
Sbjct: 707 IAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDY 766
Query: 781 CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY 840
CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY
Sbjct: 767 CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY 826
Query: 841 PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 900
PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY
Sbjct: 827 PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 886
Query: 901 DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK 960
DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK
Sbjct: 887 DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK 946
Query: 961 IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS 1008
IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS
Sbjct: 947 IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS 994
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 614 bits (1583), Expect = e-175
Identities = 372/873 (42%), Positives = 528/873 (60%), Gaps = 71/873 (8%)
Query: 183 KLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQ 242
K+ + + K+ ++ + R+ LP++ ++ ++NL+ HQV VISG TGCGKTTQ+ Q
Sbjct: 520 KICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQ 579
Query: 243 FILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPR 302
FILD+ + I+CTQPRRISAISVAERVA ERAE G + GYQIRL+S +
Sbjct: 580 FILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGL--TVGYQIRLES-VKS 636
Query: 303 KQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKV 362
+LYCTTG++L+ L+ D L VSHI++DE+HER +SD L+ V+KD+++ R L+V
Sbjct: 637 SATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQV 696
Query: 363 ILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQ----KEHRSQF 418
ILMSATLNAE FS+YF +CP+I IPG TFPV ++ LED I RYV + Q
Sbjct: 697 ILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQI 756
Query: 419 KRGFMQGHVNRQEKEEKEA------------IYKERWPDY---VRELRRRY---SASTVD 460
+ ++ NR EE E K+ PD ++L RY S S +
Sbjct: 757 SKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIK 816
Query: 461 VIEMMEDDKVDLNLIVALIRYIVLEEED---GAILVFLPGWDNISTLHDLLMSQVMF--- 514
+ +M+ +KV+L LI AL+ +IV + GAILVFLPG I L++ L S +F
Sbjct: 817 TMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNR 876
Query: 515 KSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKE 574
+S++ +I PLHS + + Q VF + P GV KI+I+TNIAETSITIDDVVYVID GK+KE
Sbjct: 877 RSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKE 936
Query: 575 THFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRAS-LLDDYQLPEILR 633
+D + ++ +VS+ANA QRKGRAGRV G C+HL+ + L QLPEI R
Sbjct: 937 KRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQR 996
Query: 634 TPLEELCLQIKILRL---GGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLG 690
PLE+LCL+IKIL + + SRL++PP +++ S L +L AL E LTPLG
Sbjct: 997 VPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLG 1056
Query: 691 VHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAK 750
HLA LPV+ IGK++LFG++F CLDP LTIAASL+FK PFV P K++ A+ ++ E A
Sbjct: 1057 YHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFA- 1115
Query: 751 DTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGF 810
SD+L ++ A++GW+ + + G R +YC + FLS LQ + ++K QF E L GF
Sbjct: 1116 FANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGF 1175
Query: 811 VSS-----------------RNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKK 853
+ E+N N++N K+I A++CA LYP V +++ GK
Sbjct: 1176 AREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKF 1235
Query: 854 RKM-------------VKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 900
+K +K TK DG V +HP SVN + F +L+YH K++TS +++
Sbjct: 1236 QKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIR 1295
Query: 901 DCTEVSPYCL-LFFGGDISIQKDNDQETIAVDE-WIVFQSPA-RIAHLVKELRKELDILL 957
DC+ VS Y L LF GG +++Q + +++D+ WI F + + ++A LVKELR ELD LL
Sbjct: 1296 DCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVKELRCELDQLL 1355
Query: 958 QEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ 990
Q+KI++P +D T R ++S I+ L+ TQ
Sbjct: 1356 QDKIKNP-SIDL-CTCPRGSRIISTIVKLVTTQ 1386
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/130 (26%), Positives = 50/130 (38%), Gaps = 21/130 (16%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG-----------------GRGR 52
G+ GG SS GG GG G GGGGGGGGGG R
Sbjct: 12 GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGDDFCIFSESR 71
Query: 53 HPGHLKGREIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKN-DKESE 111
P I ++ + + + Q +HM +E++ LL +Q ++ D SE
Sbjct: 72 RPSRPSNSNISKGESRPKWKPKAKVPLQ---TLHMTSENQEKVKALLRDLQEQDADAGSE 128
Query: 112 AQISWFAPED 121
+S +D
Sbjct: 129 RGLSGEEEDD 138
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 579 bits (1493), Expect = e-165
Identities = 349/886 (39%), Positives = 530/886 (59%), Gaps = 48/886 (5%)
Query: 138 NKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDG-TLDQKLLEDLQKKKNDLR 196
NKL Q+++ Q+ + N + E L+ + + +L+ +EDL+ +N R
Sbjct: 497 NKLKQQQQQ--QQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNLFR 554
Query: 197 -------YIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYI 249
Y ++ R++LP + + +V + H+V V++GETG GK+TQV F+L++ +
Sbjct: 555 KLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLL 614
Query: 250 -ERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNST---GYQIRLQSRLPRKQG 305
+ S C IVCTQPRRISA+S+A RV E G G GYQIR++SR
Sbjct: 615 LNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACEST- 673
Query: 306 SILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILM 365
+LYCTTG++L+ LQ D LS+VSH+++DE+HER++QSD L+ ++K++L RSDL +ILM
Sbjct: 674 RLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILM 733
Query: 366 SATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQ-KEHRSQFKRGFMQ 424
SAT+++EKFS YF +CP++ I G ++PV + LED+IE+ +V E+ E+ +F +
Sbjct: 734 SATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEE 793
Query: 425 GHVNRQEKEEKEAIYKERWPDY------VRELRRRYSASTVDVIEMMEDDKVDLNLIVAL 478
+N K Y+E P + ++YS+ T I M K++L+LI+ L
Sbjct: 794 VTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILEL 853
Query: 479 IRYIVLEEE----DGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQT 534
+ Y+ + +GA+L+FLPG +I L+DLL + F S+++ +I LHS++ T +Q
Sbjct: 854 LAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQA 913
Query: 535 QVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKA 594
F PPGVRKIV+ATNIAET ITI DVV+VID G+ KE + + +S++ +VSKA
Sbjct: 914 AAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKA 973
Query: 595 NAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYF 654
+A QR+GRAGRV+ G C+ +Y R DY +PEILR PLEELCL I LG F
Sbjct: 974 SALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDF 1033
Query: 655 LSRLMDPPSNEAVLLSIRHLMELNALDKQE-ELTPLGVHLARLPVEPHIGKMILFGALFC 713
LS+ +DPP + + ++ L ++ A + E +LTPLG HLA LPV IGKM++FGA+F
Sbjct: 1034 LSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFG 1093
Query: 714 CLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRR- 772
CLDPV T+AA ++ K PF P+G++ AD + LA SDHLT+ NA+ GW++AR+
Sbjct: 1094 CLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAM-ADSDHLTIYNAYLGWKKARQEG 1152
Query: 773 GFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESN-----INSDN 827
G+R E YC FL+ +L L ++K + + + AGF SS E N ++
Sbjct: 1153 GYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQE 1212
Query: 828 EKIIKAVICAGLYPKVAKI--RLNLGKKRKMVKVYTKTDGLVAVHPKSVNVE-QTDFHYN 884
++KAV+ AGLY V KI ++ K+ + G VHP SVN + QT +
Sbjct: 1213 IALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQT---HG 1269
Query: 885 WLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAH 944
WL+Y K+R + +YL + T ++P+ +L FGGDI +Q + + +++D WI FQ+P +IA
Sbjct: 1270 WLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQ--HRERLLSIDGWIYFQAPVKIAV 1327
Query: 945 LVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ 990
+ K+LR +D +L++K+E+P ND +L I +LIKT+
Sbjct: 1328 IFKQLRVLIDSVLRKKLENPKMSLEND------KILQIITELIKTE 1367
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 508 bits (1308), Expect = e-143
Identities = 303/787 (38%), Positives = 449/787 (57%), Gaps = 47/787 (5%)
Query: 192 KNDLRY-IEMQHF-------REKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQF 243
KN+L Y +E H RE LP + E++ I + V +I G TGCGKTTQV QF
Sbjct: 365 KNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQF 424
Query: 244 ILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRK 303
ILD++I+ + + C IV TQPRRISA+SVAERVA ER E G S GY +R +S LPR
Sbjct: 425 ILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEE--PGKSCGYSVRFESILPRP 482
Query: 304 QGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVI 363
SI++CT G++L+ L++ + +SH+++DEIHER++ +D L+ V++D++ +++++
Sbjct: 483 HASIMFCTVGVLLRKLEAG--IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIV 540
Query: 364 LMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFM 423
LMSAT++ F EYF NCP+I + G T+PV EY LED I+ +VP K+ + + K
Sbjct: 541 LMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDK---- 596
Query: 424 QGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIV 483
+ E+ +A D Y T + + + + LI AL++YI
Sbjct: 597 ----DDDGGEDDDANCNLICGD-------EYGPETRLSMSQLNEKETPFELIEALLKYIE 645
Query: 484 LEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPG 543
GA+LVFLPGW+ I T+ L F S ++ I+PLHS +P Q +VF P G
Sbjct: 646 TLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGSHRYQILPLHSQIPREEQRKVFDPVPVG 705
Query: 544 VRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRA 603
V K++++TNIAETSITI+DVVYVID K K F NN++ + W SK N +QRKGRA
Sbjct: 706 VTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRA 765
Query: 604 GRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPS 663
GRV+PG C+HL + R L+ + PE+ RTPL E+ L IK+LRLGGI FL++ ++PP
Sbjct: 766 GRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPP 825
Query: 664 NEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAA 723
+AV+ + L EL+ALD +ELTPLG LA+LP+EP GKM++ G +F D + TIAA
Sbjct: 826 LDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAA 885
Query: 724 SLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWE 783
+ F +PF+ + K + A + SDH+ +++ F+ W++AR G E +C
Sbjct: 886 ATCFPEPFI---NEGKRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEH 942
Query: 784 YFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNE-KIIKAVICAGLYPK 842
L+ TL+M K Q E L+ +GF +N DN ++ +++ G+YP
Sbjct: 943 KRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPN 1002
Query: 843 VAKIRLNLGKKRKMVKVYTKTDGLVA-VHPKSVN--VEQTDFHY--NWLIYHLKMRTSSI 897
V + +KRK++ T+G A +H SVN D Y + ++ K+RT +I
Sbjct: 1003 VCYHK----EKRKIL----TTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAI 1054
Query: 898 YLYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILL 957
T V+P LL F S + +D + + VD+WI Q A + LR ++ L+
Sbjct: 1055 SAKGMTLVTPLQLLLFA---SKKVQSDGQIVLVDDWIKLQISHEAAACITGLRAAMEALV 1111
Query: 958 QEKIESP 964
E + P
Sbjct: 1112 VEVTKQP 1118
Score = 44.7 bits (104), Expect = 4e-04
Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 11 RDGGPRSSGGGYGGG------PAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIGM 64
R GG SGGGYGGG +GG+GG+ S G G G G G RG G +G G
Sbjct: 1174 RRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGD 1233
Query: 65 WYAKKQGQK 73
+ G +
Sbjct: 1234 YRGPSGGYR 1242
Score = 37.7 bits (86), Expect = 0.055
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 13 GGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG--GRGRHPG 55
GG R + GG GP+GG+ G+ G GGG G G G G+GR G
Sbjct: 1224 GGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGG 1268
Score = 35.8 bits (81), Expect = 0.21
Identities = 24/51 (47%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG-GRGRHPGHLKG 59
G GG SS GGYG G GG + +G G G GGG RG RG G+ G
Sbjct: 1183 GGYGGGYSS-GGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGG 1232
Score = 35.0 bits (79), Expect = 0.36
Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 7/57 (12%)
Query: 10 GRDGGPRSSGGGYGGGPAGGH-----GGNRGSGGGG--GGGGGGRGGRGRHPGHLKG 59
G G S GYG G GG+ GG RG+ GG G GG RG G G +G
Sbjct: 1198 GYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRG 1254
Score = 34.3 bits (77), Expect = 0.61
Identities = 26/59 (44%), Positives = 26/59 (44%), Gaps = 10/59 (16%)
Query: 3 YDYHQNWGRDGGPRSSGGGYGGGPAGGHGGN-----RGSGGG--GGGG---GGGRGGRG 51
Y N R G GGGY G GG GN RG GG G GG GGGRG G
Sbjct: 1199 YGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYG 1257
Score = 33.1 bits (74), Expect = 1.4
Identities = 18/34 (52%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHG-GNRGSGGGGGG 42
G GG R SGG GG G +G G G G GGGG
Sbjct: 1236 GPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo
sapiens]
Length = 1155
Score = 496 bits (1277), Expect = e-140
Identities = 283/776 (36%), Positives = 443/776 (57%), Gaps = 71/776 (9%)
Query: 206 KLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPR 265
+LP + ++N I+ H V VISG+TGCGKTT++ Q +L+ Y+ G+G+ C ++ TQPR
Sbjct: 394 QLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPR 453
Query: 266 RISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYL 325
RISA+SVA+RV+ E S + G+Q+RL+S+ P + G++L+CT GI+L+ LQS+P L
Sbjct: 454 RISAVSVAQRVSHELGPSLR--RNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSL 511
Query: 326 SSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIH 385
VSH+++DE+HER++ +D L+ ++K L L+++LMSAT + E+FS YFG CP+I
Sbjct: 512 EGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIK 571
Query: 386 IPGFTFPVVEYLLEDVIEKI---RYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442
+PGF +PV E+ LED++ K+ +Y+ + H S+
Sbjct: 572 VPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESE------------------------- 606
Query: 443 WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502
++ +DL+L+ L+ +I E G IL FLPGW I
Sbjct: 607 -----------------------DECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIK 643
Query: 503 TLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDD 562
+ L + K+LI+P+HS +P ++Q +F++ P GVRKIV+ATNIAETSITI+D
Sbjct: 644 GVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITIND 703
Query: 563 VVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASL 622
+V+V+D G KE +D + +S + WVS+AN QR+GRAGR Q G YHL+ R
Sbjct: 704 IVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEK 763
Query: 623 LDDYQLPEILRTPLEELCLQIKILRLGGIAY-FLSRLMDPPSNEAVLLSIRHLMELNALD 681
+ +Q+PEILRTPLE L LQ KI A FLS+ +D P+ +AV ++ L E+ LD
Sbjct: 764 MVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLD 823
Query: 682 KQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIA 741
++E LT LG LA + +P + K I+ A+F CL P+L + + L+ +DPF L
Sbjct: 824 QREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEV 882
Query: 742 DARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKD-YCWEYFLSSNTLQMLHNMKGQ 800
D + L+ D+ SDHL V A GWEE R R ++ Y E L + +L+ +H + Q
Sbjct: 883 DKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQ 942
Query: 801 FAEHLLGAGFVSSRNPKD-----PESNINSDNEKIIKAVICAGLYPKVAKIR----LNLG 851
F+E++ A V P D + N S+ E+++K V+ AGLYP + ++R G
Sbjct: 943 FSENIYEAFLVG--KPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQG 1000
Query: 852 KKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTS-SIYLYDCTEVSPYC- 909
K + Y G + +H ++N E T WL Y + ++++ S+++ D ++V P
Sbjct: 1001 KFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAV 1060
Query: 910 LLFFGGDISIQKDNDQETIAV--DEWIVFQSPARIAHLVKELRKELDILLQEKIES 963
LL GD+ I+ D + TI++ + + + +R L+KELR+ L +++ + S
Sbjct: 1061 LLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRS 1116
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo
sapiens]
Length = 1194
Score = 496 bits (1277), Expect = e-140
Identities = 283/776 (36%), Positives = 443/776 (57%), Gaps = 71/776 (9%)
Query: 206 KLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPR 265
+LP + ++N I+ H V VISG+TGCGKTT++ Q +L+ Y+ G+G+ C ++ TQPR
Sbjct: 433 QLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPR 492
Query: 266 RISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYL 325
RISA+SVA+RV+ E S + G+Q+RL+S+ P + G++L+CT GI+L+ LQS+P L
Sbjct: 493 RISAVSVAQRVSHELGPSLR--RNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSL 550
Query: 326 SSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIH 385
VSH+++DE+HER++ +D L+ ++K L L+++LMSAT + E+FS YFG CP+I
Sbjct: 551 EGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIK 610
Query: 386 IPGFTFPVVEYLLEDVIEKI---RYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442
+PGF +PV E+ LED++ K+ +Y+ + H S+
Sbjct: 611 VPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESE------------------------- 645
Query: 443 WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502
++ +DL+L+ L+ +I E G IL FLPGW I
Sbjct: 646 -----------------------DECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIK 682
Query: 503 TLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDD 562
+ L + K+LI+P+HS +P ++Q +F++ P GVRKIV+ATNIAETSITI+D
Sbjct: 683 GVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITIND 742
Query: 563 VVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASL 622
+V+V+D G KE +D + +S + WVS+AN QR+GRAGR Q G YHL+ R
Sbjct: 743 IVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEK 802
Query: 623 LDDYQLPEILRTPLEELCLQIKILRLGGIAY-FLSRLMDPPSNEAVLLSIRHLMELNALD 681
+ +Q+PEILRTPLE L LQ KI A FLS+ +D P+ +AV ++ L E+ LD
Sbjct: 803 MVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLD 862
Query: 682 KQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIA 741
++E LT LG LA + +P + K I+ A+F CL P+L + + L+ +DPF L
Sbjct: 863 QREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEV 921
Query: 742 DARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKD-YCWEYFLSSNTLQMLHNMKGQ 800
D + L+ D+ SDHL V A GWEE R R ++ Y E L + +L+ +H + Q
Sbjct: 922 DKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQ 981
Query: 801 FAEHLLGAGFVSSRNPKD-----PESNINSDNEKIIKAVICAGLYPKVAKIR----LNLG 851
F+E++ A V P D + N S+ E+++K V+ AGLYP + ++R G
Sbjct: 982 FSENIYEAFLVG--KPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQG 1039
Query: 852 KKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTS-SIYLYDCTEVSPYC- 909
K + Y G + +H ++N E T WL Y + ++++ S+++ D ++V P
Sbjct: 1040 KFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAV 1099
Query: 910 LLFFGGDISIQKDNDQETIAV--DEWIVFQSPARIAHLVKELRKELDILLQEKIES 963
LL GD+ I+ D + TI++ + + + +R L+KELR+ L +++ + S
Sbjct: 1100 LLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRS 1155
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
sapiens]
Length = 1143
Score = 348 bits (894), Expect = 1e-95
Identities = 220/682 (32%), Positives = 347/682 (50%), Gaps = 79/682 (11%)
Query: 187 DLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILD 246
D +K+ R ++Q R LP ++ + HQV V++G+TGCGK+TQV Q++L
Sbjct: 142 DFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL- 200
Query: 247 NYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGS 306
+ CTQPRRI+ IS+A+RV E GS GYQIR +S
Sbjct: 201 ------AAGFSHVACTQPRRIACISLAKRVGFESLSQYGS--QVGYQIRFESTRSAAT-K 251
Query: 307 ILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMS 366
I++ T G++L+ +Q +P L +++DE+HER+L +D L+ V++ LL R DLKVILMS
Sbjct: 252 IVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMS 311
Query: 367 ATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGH 426
AT+N FS YF N P++ +PG FP+ + Y P++ E +
Sbjct: 312 ATINISLFSSYFSNAPVVQVPGRLFPIT----------VVYQPQEAEPTT---------- 351
Query: 427 VNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEE 486
++ EK + + ++ I + E
Sbjct: 352 -SKSEKLDPRPFLR----------------------------------VLESIDHKYPPE 376
Query: 487 EDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRK 546
E G +LVFL G IS + + + + +++++PLHS + +Q +VF PPGVRK
Sbjct: 377 ERGDLLVFLSGMAEISAVLEAAQTYASH-TQRWVVLPLHSALSVADQDKVFDVAPPGVRK 435
Query: 547 IVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRV 606
+++TNIAETS+TID + +V+D GK+KE +D Q + + W+S+A+A+QRKGRAGR
Sbjct: 436 CILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT 495
Query: 607 QPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEA 666
PG C+ LY Y +PEI R L+ L LQ+K + +G F ++PP +
Sbjct: 496 GPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTF--PFIEPPPPAS 553
Query: 667 VLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLS 726
+ +I +L + ALD E LTP+G LA+LPV+ IGKM++ G++F ++PVLTIAA+LS
Sbjct: 554 LETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALS 613
Query: 727 FKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFL 786
+ PF A R+ L D + D T+ N F W + + R + +C +
Sbjct: 614 VQSPFTRSAQSSPECAAARRPLESD-QGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGI 672
Query: 787 SSNTLQMLHNMKGQFAEHLLGAGFVSSRNPK---DPESNINSDNEKIIKAVICAGLYPKV 843
+ L + N++ QF E L G ++ D S + E+ L+
Sbjct: 673 EEHRLYEMANLRRQFKELLEDHGLLAGAQAAQVGDSYSRLQQRRER-------RALHQLK 725
Query: 844 AKIRLNLGKKRKMVKVYTKTDG 865
+ G++RK++++ + DG
Sbjct: 726 RQHEEGAGRRRKVLRLQEEQDG 747
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 334 bits (857), Expect = 2e-91
Identities = 212/594 (35%), Positives = 329/594 (55%), Gaps = 64/594 (10%)
Query: 448 RELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDL 507
REL + Y S +D+KVDL+LI+ L+ I + GA+L+FLPG+D I L D
Sbjct: 589 RELLKAYHHS-------FDDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDR 641
Query: 508 LM---SQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVV 564
++ + + ++ + LHS M T +Q +V K P GVRKI+++TNIAETSIT++DVV
Sbjct: 642 ILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVV 701
Query: 565 YVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLD 624
+VID GK+KE FD N ++ + W+SKA+A QRKGRAGR +PG C+ L++ LR +
Sbjct: 702 FVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNML 761
Query: 625 DYQLPEILRTPLEELCLQIKILRLGG--IAYFLSRLMDPPSNEAVLLSIRHLMELNALDK 682
++Q PE+LR PL+ELCL K+L IA FL + +PP V +++ L ++A+D
Sbjct: 762 EFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDT 821
Query: 683 QEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIP--LGKEKI 740
E+LT LG HLA LPVEPH+GKM+L + CLDP+LTIA +L+++DPFV+P +++
Sbjct: 822 WEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRA 881
Query: 741 ADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQ 800
A RK SDH+ ++ AF+ W++AR G +E+ +C + FLS T++++ M+ Q
Sbjct: 882 AMLCRKRFTAGAFSDHMALLRAFQAWQKARSDG--WERAFCEKNFLSQATMEIIIGMRTQ 939
Query: 801 FAEHLLGAGFVSSRNPKD-PESNINSDNEKIIKAVICAGLYPKVAKI-RLNL---GKKRK 855
L +GFV +R D + N NS+N ++KA + AG+YP + + R NL G K K
Sbjct: 940 LLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEK 999
Query: 856 MVKVYTKTDGLVAVHPKSVNVEQTD--------FHYNWLIYHLKMRTSSI-YLYDCTEVS 906
V+ + + V P+ + + +WLIY R I + C+ V+
Sbjct: 1000 KVRFHPAS---VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVT 1056
Query: 907 PYCLLFFGGDISIQKDNDQE---------------------------TIAVDEWIVFQSP 939
P +L F G + + QE + +DEW+ F
Sbjct: 1057 PVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLE 1116
Query: 940 ARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKA 993
A L+ +LR++ L ++ +P W+ D A + AII ++ T+E++
Sbjct: 1117 PEAASLLLQLRQKWHSLFLRRMRAPSK-PWSQV---DEATIRAIIAVLSTEEQS 1166
Score = 194 bits (493), Expect = 4e-49
Identities = 144/428 (33%), Positives = 219/428 (51%), Gaps = 47/428 (10%)
Query: 35 GSGGGGGGGGGGRGGRGRHPGHLKGR-----EIGMWYAKKQGQKNKEAERQ--------E 81
G GGGGG G GG GR G R +I + A ++ + + E + E
Sbjct: 15 GGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTE 74
Query: 82 RAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPED----HGYGTEVSTKNTPCSE 137
RA +H ++ Q L V K + ++ + H T T NT +
Sbjct: 75 RAFIH-------RLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAV 127
Query: 138 NKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQ-ENEPDGTLDQKLLEDLQKKKNDLR 196
L IQ + N+E+ + +R + + ++ EN +L + +
Sbjct: 128 RSL-IQRFPVTNKERTELLPKT----ERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRG 182
Query: 197 YIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSA 256
E FR+ LP + Q+E+V +I ++V +I GETG GKTTQ+ QF+LD+ + G
Sbjct: 183 ESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNG--IP 240
Query: 257 CRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIIL 316
CRI CTQPRR++AI+VAERVAAER E G + GYQIRL+SR+ K + +CT G++L
Sbjct: 241 CRIFCTQPRRLAAIAVAERVAAERRERIGQ--TIGYQIRLESRVSPKT-LLTFCTNGVLL 297
Query: 317 QWLQS-DPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFS 375
+ L + D LS+V+H+++DE+HER+ SD L+T ++DLL LK+IL SA L+ F
Sbjct: 298 RTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFI 357
Query: 376 EYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEK 435
YFG+CP+I+I G F V E LED++ Y ++ M + +++EEK
Sbjct: 358 RYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKE-----------MLKYKKEKQQEEK 406
Query: 436 EAIYKERW 443
+ W
Sbjct: 407 QQTTLTEW 414
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
sapiens]
Length = 795
Score = 315 bits (806), Expect = 2e-85
Identities = 228/726 (31%), Positives = 360/726 (49%), Gaps = 102/726 (14%)
Query: 196 RYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGS 255
RY ++ R +LP + + +++ HQ V+ GETG GKTTQ+ Q+ ++ Y+ G
Sbjct: 126 RYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVE-YMRSLPGP 184
Query: 256 ACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGII 315
+ CTQPRR++A+SVA+RVA E G GY IR + K + Y T G++
Sbjct: 185 KRGVACTQPRRVAAMSVAQRVADEMDVMLGQ--EVGYSIRFEDCSSAKT-ILKYMTDGML 241
Query: 316 LQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFS 375
L+ +DP L I+LDE HER L +D+LM V+K+++ RSDLKVI+MSATL+A KF
Sbjct: 242 LREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQ 301
Query: 376 EYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEK 435
YF NCP++ IPG T PV +I Y PE +
Sbjct: 302 IYFDNCPLLTIPGRTHPV----------EIFYTPEPER---------------------- 329
Query: 436 EAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFL 495
DY+ R TV I M E EE+G +L+FL
Sbjct: 330 ---------DYLEAAIR-----TVIQIHMCE-------------------EEEGDLLLFL 356
Query: 496 PGWDNISTLHDLLMSQVMFKSDK---FLIIPLHSLMPTVNQTQVFKRTPPGV------RK 546
G + I + +V + IIPL+S +P Q ++F+ PP RK
Sbjct: 357 TGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRK 416
Query: 547 IVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRV 606
+V++TNIAETS+TID VV+VID G K+ ++ + + ++ +SKA+A+QR GRAGR
Sbjct: 417 VVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRT 476
Query: 607 QPGHCYHLY-NGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNE 665
+PG C+ LY + + D PEILR+ L + LQ+K L + + +F MDPP+ E
Sbjct: 477 RPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHF--DFMDPPAPE 534
Query: 666 AVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASL 725
++ ++ L L AL+ +LT LG +A P++P + KM++ + C + VL+I A L
Sbjct: 535 TLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAML 594
Query: 726 SFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYF 785
S FV P +K AD + A DHLT++N + +++ +C++ F
Sbjct: 595 SVPQCFVRPTEAKKAADEAKMRFA-HIDGDHLTLLNVYHAFKQNHE-----SVQWCYDNF 648
Query: 786 LSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAK 845
++ +L N++ Q + + P+ + D I+ + G + +VA
Sbjct: 649 INYRSLMSADNVRQQLSRIMDRFNL-----PRRSTDFTSRDYYINIRKALVTGYFMQVAH 703
Query: 846 IRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEV 905
+ +R + K + +V +HP +V D W++Y+ + T+ Y+ CT++
Sbjct: 704 L------ERTGHYLTVKDNQVVQLHPSTV----LDHKPEWVLYNEFVLTTKNYIRTCTDI 753
Query: 906 SPYCLL 911
P L+
Sbjct: 754 KPEWLV 759
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 299 bits (766), Expect = 8e-81
Identities = 203/596 (34%), Positives = 318/596 (53%), Gaps = 65/596 (10%)
Query: 207 LPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRR 266
LP ++E+V+LI+++ V +I G TG GK+TQ+ Q+ILD+Y++R + C IV TQPR+
Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRS--AYCSIVVTQPRK 189
Query: 267 ISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLS 326
I A S+A ++ ERA + G GYQ+ L+ ++ + ++Y TTG++LQ + S L
Sbjct: 190 IGASSIARWISKERAWTLGG--VVGYQVGLE-KIATEDTRLIYMTTGVLLQKIVSAKSLM 246
Query: 327 SVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD-LKVILMSATLNAEKFSEYFG------ 379
+HI++DE+HER + D L+ VV+ LL S +KV+LMSAT++ ++F++YF
Sbjct: 247 EFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNK 306
Query: 380 --NCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEA 437
+ + G V EY L D+ + H S+ ++ V ++
Sbjct: 307 MNPAYIFEVEGKPHSVEEYYLNDL---------EHIHHSKLSPHLLEEPVITKD------ 351
Query: 438 IYKERWPDYVRELRRRYSASTVDVIEMMED--DKVDLNLIVALIRYIVLEEEDGAILVFL 495
IY+ V +I+M +D K N + ++++ E ++LVFL
Sbjct: 352 IYEV----------------AVSLIQMFDDLDMKESGNKAWSGAQFVL---ERSSVLVFL 392
Query: 496 PGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAE 555
PG I+ +H+LL S V + + PLHS + Q VF PG RKI+++TNIAE
Sbjct: 393 PGLGEINYMHELLTSLV---HKRLQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAE 449
Query: 556 TSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHL- 614
+S+T+ DV YVID + D N ++ W SK + QRKGRAGRV G+CY L
Sbjct: 450 SSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLV 509
Query: 615 YNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHL 674
+ + + D+ +PE+LR PL L++K+L +G L+ + PP + +I L
Sbjct: 510 HKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPPGLSDIERTILLL 569
Query: 675 MELNAL----------DKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAAS 724
E+ AL ELT LG LA+LPV +GK+I+ G +F CLD L IAA+
Sbjct: 570 KEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAA 629
Query: 725 LSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRG-FRYEKD 779
LS K+ F +P + + + ++SD + +V AF+ W+ R+ G RY KD
Sbjct: 630 LSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALVEAFKTWKACRQTGELRYPKD 685
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
sapiens]
Length = 703
Score = 295 bits (756), Expect = 1e-79
Identities = 214/738 (28%), Positives = 359/738 (48%), Gaps = 118/738 (15%)
Query: 193 NDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERG 252
N + ++ R+KLP + ++ ++ LI+N+Q VI GETGCGK+TQ+ Q++ E G
Sbjct: 40 NPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLA----EAG 95
Query: 253 KGSACRIV-CTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCT 311
+ R+V TQPRR++A++VA RVA ER G + GY IR + I + T
Sbjct: 96 WTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLG--HEVGYCIRFDDCTDQLATRIKFLT 153
Query: 312 TGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNA 371
G++++ + DP L+ S I+LDE HER L +D+ + ++K + R DL++I+ SATL+A
Sbjct: 154 DGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDA 213
Query: 372 EKFSEYFGN----------CPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRG 421
+KF ++F C ++ + G TFPV + L+ +
Sbjct: 214 DKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPV------------------- 254
Query: 422 FMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRY 481
PDY++ STV+ + +
Sbjct: 255 ----------------------PDYIK--------STVETVVKIHQT------------- 271
Query: 482 IVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFL-----IIPLHSLMPTVNQTQV 536
E DG +L FL G + + T+ +L+ Q + + ++P+++ +P+ Q +V
Sbjct: 272 ----EGDGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKV 327
Query: 537 FKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANA 596
F+R VRK+++ATN+AETSITI +VYVID G +K ++ + I + VS+A+A
Sbjct: 328 FERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASA 387
Query: 597 KQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLS 656
QR GR GR + G CY LY L +PE+ R+ L + LQ+K L + + F
Sbjct: 388 NQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRF-- 445
Query: 657 RLMDPPSNEAVLLSIRHLMELNALDKQEELT-PLGVHLARLPVEPHIGKMILFGALFCCL 715
M PP ++++ ++ L L LDK LT PLG+ +A P+ P KM+L F C
Sbjct: 446 HFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCS 505
Query: 716 DPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFR 775
+L+IAA + ++ FV+P ++ A ++ A + DHLT++N +E + +
Sbjct: 506 QEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVE-EGDHLTMLNIYEAF-------IK 557
Query: 776 YEKD--YCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKA 833
+ KD +C E+FL+ L ++ Q + L+ + DP+ ++
Sbjct: 558 HNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDPD---------LVLR 608
Query: 834 VICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMR 893
I +G + A+ + G R + + D + +HP SV + W+IY+ ++
Sbjct: 609 CIVSGFFANAARFH-STGAYRTI-----RDDHELHIHPASVLYAEKP--PRWVIYNEVIQ 660
Query: 894 TSSIYLYDCTEVSPYCLL 911
TS Y+ D T + LL
Sbjct: 661 TSKYYMRDVTAIESAWLL 678
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 287 bits (735), Expect = 3e-77
Identities = 218/744 (29%), Positives = 368/744 (49%), Gaps = 110/744 (14%)
Query: 172 QENEPDGTLDQKLLEDLQKKKND----LRYIEMQHFREKLPSYGMQKELVNLIDNHQVTV 227
++ + D +QK + +++K + + R+ LP + +Q+EL+ +I ++ + +
Sbjct: 493 EDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVI 552
Query: 228 ISGETGCGKTTQVTQFIL-DNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGS 286
+ GETG GKTTQ+TQ++ D Y + G I CTQPRR++A+SVA+RV+ E + G
Sbjct: 553 VVGETGSGKTTQLTQYLHEDGYTDYGM-----IGCTQPRRVAAMSVAKRVSEEMGGNLGE 607
Query: 287 GNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVL 346
GY IR + + I Y T GI+L+ + L S I++DE HER+L +DVL
Sbjct: 608 --EVGYAIRFED-CTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVL 664
Query: 347 MTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIR 406
++++++ RSDLK+I+ SAT++AEKF+ +FGN P+ HIPG TFPV D++
Sbjct: 665 FGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPV------DIL---- 714
Query: 407 YVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMM- 465
F + + +V K+ L+ S + D++ M
Sbjct: 715 -----------FSKTPQEDYVEAAVKQ---------------SLQVHLSGAPGDILIFMP 748
Query: 466 --EDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIP 523
ED +V + IV + E E+ L LP
Sbjct: 749 GQEDIEVTSDQIVEHLE----ELENAPALAVLP--------------------------- 777
Query: 524 LHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNI 583
++S +P+ Q ++F++ P GVRK ++ATNIAETS+T+D +++VID G K F+ + +
Sbjct: 778 IYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGM 837
Query: 584 STMSAEWVSKANAKQRKGRAGRVQPGHCYHLY--NGLRASLLDDYQLPEILRTPLEELCL 641
+ +S+ANA QR GRAGR PG C+ LY + + LL +PEI RT L + L
Sbjct: 838 DALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTT-TVPEIQRTNLANVVL 896
Query: 642 QIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPH 701
+K L + + F MDPP + +L S+ L L ALD LT G + P++P
Sbjct: 897 LLKSLGVQDLLQF--HFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPA 954
Query: 702 IGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVN 761
+ KM++ C +L I + LS F P G+E+ +D R++ A SDHLT +N
Sbjct: 955 LSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAV-PESDHLTYLN 1013
Query: 762 AFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES 821
+ W + Y +C ++F+ + ++ + ++ Q + ++ + D +
Sbjct: 1014 VYLQW-----KNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWD- 1067
Query: 822 NINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDF 881
I++ ICA + + AK++ +G+ V +T +HP S ++ +
Sbjct: 1068 --------IVRKCICAAYFHQAAKLK-GIGE-----YVNIRTGMPCHLHPTS-SLFGMGY 1112
Query: 882 HYNWLIYHLKMRTSSIYLYDCTEV 905
++++YH + T+ Y+ T V
Sbjct: 1113 TPDYIVYHELVMTTKEYMQCVTAV 1136
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
sapiens]
Length = 779
Score = 281 bits (719), Expect = 2e-75
Identities = 205/714 (28%), Positives = 338/714 (47%), Gaps = 110/714 (15%)
Query: 208 PSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRI 267
P +K+++ + ++ +++G TG GKTTQ+ +++ E G I TQPR++
Sbjct: 54 PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLY----EAGFSQHGMIGVTQPRKV 109
Query: 268 SAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSS 327
+AISVA+RVA E C G+ GYQ+R K+ +I Y T G +L+ + DP L+
Sbjct: 110 AAISVAQRVAEEM--KCTLGSKVGYQVRFDD-CSSKETAIKYMTDGCLLKHILGDPNLTK 166
Query: 328 VSHIVLDEIHERNLQSDVLMTVVKDLL-----NFRSDLKVILMSATLNAEKFSEYFGNCP 382
S I+LDE HER L +D+L ++K L N + LKV++MSAT+ K S +FGNCP
Sbjct: 167 FSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCP 226
Query: 383 MIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442
+ IPG +PV +E+
Sbjct: 227 IFDIPGRLYPV----------------------------------------------REK 240
Query: 443 WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502
+ + + R +A ++E+ D + LN E G ILVFL G I
Sbjct: 241 FCNLIGPRDRENTAYIQAIVEVTMD--IHLN------------EMAGDILVFLTGQFEIE 286
Query: 503 TLHDLLMSQVMFKS----------DKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATN 552
+LL D LI+P + M T Q ++F PPG+RK VI+TN
Sbjct: 287 KSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTN 346
Query: 553 IAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCY 612
I+ TS+TID + YV+DGG +K+ + + + + + +SK+ A QR GRAGR G C+
Sbjct: 347 ISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCF 406
Query: 613 HLYN-GLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSI 671
+Y+ + D+ +PEI RT L + L +K L + + F +DPP+ +L ++
Sbjct: 407 RIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRF--PYLDPPNERLILEAL 464
Query: 672 RHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPF 731
+ L + +A+D+ +T LG+ + P+ PH+ ++ A C D +L IAA LS ++ F
Sbjct: 465 KQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVF 524
Query: 732 VIPLGKE--KIADARRKELAKDTR--SDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLS 787
+ P+ E K A+ R +ELA +D T+ F E+ + G +C ++++
Sbjct: 525 IRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIF---EQCKSSG--APASWCQKHWIH 579
Query: 788 SNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIR 847
L ++ Q E + + P+ ++++ +CAG + VA
Sbjct: 580 WRCLFSAFRVEAQLRELIRKL----KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVA--- 632
Query: 848 LNLGKKRKMVKVYTKTDGL---VAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIY 898
+R + + + DG V +HP S EQ + W+I+H + T+ +Y
Sbjct: 633 -----RRSVGRTFCTVDGRGSPVHIHPSSALHEQ-ETKLEWIIFHEVLVTTKVY 680
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
sapiens]
Length = 1157
Score = 235 bits (600), Expect = 1e-61
Identities = 180/591 (30%), Positives = 293/591 (49%), Gaps = 79/591 (13%)
Query: 199 EMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACR 258
EMQ R KLP ++ ++ + H + ++ GETG GKTTQV QF+ E G S
Sbjct: 244 EMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLY----EAGFSSEDS 299
Query: 259 IV-CTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQ 317
I+ T+PRR++A+++++RVA E S YQIR + + ++ I + T G++L+
Sbjct: 300 IIGVTEPRRVAAVAMSQRVAKEMNLS---QRVVSYQIRYEGNVT-EETRIKFMTDGVLLK 355
Query: 318 WLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD----LKVILMSATLNAEK 373
+Q D L +++DE HER++ +D+L+ ++ ++ R+ LK+++MSATL E
Sbjct: 356 EIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVED 415
Query: 374 FSE----YFGNCPMIHIPGFTFPVVEYL-----LED--------VIEKIRYVPE------ 410
F++ + P+I + FPV + LED V + R +P
Sbjct: 416 FTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVF 475
Query: 411 ---QKEHRS---QFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEM 464
Q E + + ++ F QEK++ + E + ++ R R + +V+
Sbjct: 476 LTGQAEVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKF-KKSRARAKKARAEVLPQ 534
Query: 465 MEDDKVDLNLIVA----LIRYIVLEEEDGAI-----LVFLPGWDNISTLHDLLMSQVMFK 515
+ D +++ A R ++EE+GA+ L G + D +
Sbjct: 535 INLDHY--SVLPAGEGDEDREAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLP----- 587
Query: 516 SDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKET 575
++PL+SL+ Q QVFK P G R V+ATN+AETS+TI + YV+D GK+K+
Sbjct: 588 ---LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKR 644
Query: 576 HFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTP 635
++D +S+ WVS+A+A QR GRAGR +PGHCY LY+ + + PEI R P
Sbjct: 645 YYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRP 704
Query: 636 LEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEE---------- 685
+E+L LQ+K L + + F PPS EA+L + L+ L AL ++
Sbjct: 705 VEDLILQMKALNVEKVINF--PFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQEN 762
Query: 686 -----LTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPF 731
+T LG +A PV P KM+ CL +TI AS++ ++ F
Sbjct: 763 RLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF 813
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 214 bits (544), Expect = 4e-55
Identities = 145/453 (32%), Positives = 235/453 (51%), Gaps = 34/453 (7%)
Query: 466 EDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSD---KFLII 522
E D +D +LI + I L E G ILVFL G + I T ++L ++ + +I+
Sbjct: 753 ETDYLDASLITVM--QIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIIL 810
Query: 523 PLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNN 582
P++S +P+ QT++F PPG RK+VIATNIAETS+TID + YV+D G +K+ ++++
Sbjct: 811 PVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTG 870
Query: 583 ISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLY--NGLRASLLDDYQLPEILRTPLEELC 640
I + +S+A AKQR GRAGR PG CY LY R +L +PEI RT L
Sbjct: 871 IDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTT-NVPEIQRTNLASTV 929
Query: 641 LQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEP 700
L +K + + + F MD P E ++ ++ L L ALD + LT LG +A P+EP
Sbjct: 930 LSLKAMGINDLLSF--DFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEP 987
Query: 701 HIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVV 760
+ KM++ C + +LTI + LS ++ F P K+ +AD ++K T DHLT++
Sbjct: 988 MLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALAD-QKKAKFHQTEGDHLTLL 1046
Query: 761 NAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPE 820
+ W + ++ +C+E F+ + +L+ +++ Q +LG + R+ D
Sbjct: 1047 AVYNSW-----KNNKFSNPWCYENFIQARSLRRAQDIRKQ----MLG---IMDRHKLDVV 1094
Query: 821 SNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTD 880
S ++ KA IC+G + AK G + + +V +HP S +
Sbjct: 1095 S-CGKSTVRVQKA-ICSGFFRNAAKKDPQEGYRTLI------DQQVVYIHPSSALFNRQP 1146
Query: 881 FHYNWLIYHLKMRTSSIYLYDCTEVSPYCLLFF 913
W++YH + T+ Y+ + T + P L+ F
Sbjct: 1147 ---EWVVYHELVLTTKEYMREVTTIDPRWLVEF 1176
Score = 151 bits (381), Expect = 3e-36
Identities = 86/204 (42%), Positives = 127/204 (62%), Gaps = 12/204 (5%)
Query: 191 KKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILD-NYI 249
KK + +E RE LP Y ++++LV + ++Q+ ++ GETG GKTTQ+TQ++ + Y
Sbjct: 552 KKTQMSILEQ---RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYT 608
Query: 250 ERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILY 309
RGK I CTQPRR++A+SVA+RV+ E C G GY IR + + I Y
Sbjct: 609 SRGK-----IGCTQPRRVAAMSVAKRVSEEFG--CCLGQEVGYTIRFED-CTSPETVIKY 660
Query: 310 CTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATL 369
T G++L+ DP L+ + I+LDE HER + +DVL ++K + R D+K+I+ SATL
Sbjct: 661 MTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATL 720
Query: 370 NAEKFSEYFGNCPMIHIPGFTFPV 393
+A KFS+YF P+ IPG T+PV
Sbjct: 721 DAVKFSQYFYEAPIFTIPGRTYPV 744
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 208 bits (530), Expect = 2e-53
Identities = 138/454 (30%), Positives = 223/454 (49%), Gaps = 63/454 (13%)
Query: 208 PSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRI 267
P +K+++ + ++ +++G TG GKTTQ+ +++ E G I TQPR++
Sbjct: 54 PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLY----EAGFSQHGMIGVTQPRKV 109
Query: 268 SAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSS 327
+AISVA+RVA E C G+ GYQ+R K+ +I Y T G +L+ + DP L+
Sbjct: 110 AAISVAQRVAEEM--KCTLGSKVGYQVRFDD-CSSKETAIKYMTDGCLLKHILGDPNLTK 166
Query: 328 VSHIVLDEIHERNLQSDVLMTVVKDLL-----NFRSDLKVILMSATLNAEKFSEYFGNCP 382
S I+LDE HER L +D+L ++K L N + LKV++MSAT+ K S +FGNCP
Sbjct: 167 FSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCP 226
Query: 383 MIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442
+ IPG +PV E + G +R+ +AI K
Sbjct: 227 IFDIPGRLYPVREKFCN-----------------------LIGPRDRENTAYIQAIVKVT 263
Query: 443 WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502
++ E+ +++V L +E+ + D
Sbjct: 264 MDIHLNEMAG--------------------DILVFLTGQFEIEKSCELLFQMAESVDYDY 303
Query: 503 TLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDD 562
+ D ++ D LI+P + M T Q ++F PPG+RK VI+TNI+ TS+TID
Sbjct: 304 DVQDTIL-------DGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDG 356
Query: 563 VVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYN-GLRAS 621
+ YV+DGG +K+ + + + + + +SK+ A QR GRAGR G C+ +Y+
Sbjct: 357 IRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQ 416
Query: 622 LLDDYQLPEILRTPLEELCLQIKILRLGGIAYFL 655
+ D+ +PEI RT L + L +K L + + ++
Sbjct: 417 CMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRYV 450
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 194 bits (493), Expect = 4e-49
Identities = 146/458 (31%), Positives = 228/458 (49%), Gaps = 32/458 (6%)
Query: 459 VDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMS---QVMFK 515
VD+ + L V + I + + G ILVFL G + I ++L ++ K
Sbjct: 579 VDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDPCRRLGSK 638
Query: 516 SDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKET 575
+ L++P+++ +P+ Q ++F+ TPPG RK+V+ATNIAETS TI+ ++YV+D G K+
Sbjct: 639 IRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQK 698
Query: 576 HFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNG-LRASLLDDYQLPEILRT 634
++ + + +++ SKA+A QR GRAGRV G C+ LY L++ +PEI RT
Sbjct: 699 SYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRT 758
Query: 635 PLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLA 694
L + L +K L + + +F +DPP E +LL++ L L AL+ ELT G +A
Sbjct: 759 SLGNVVLLLKSLGIHDLMHF--DFLDPPPYETLLLTLEQLYALGALNHLGELTTSGRKMA 816
Query: 695 RLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP-FVIPLGKEKIADARRKELAKDTR 753
LPV+P + KMIL + C + +LT+AA LS + F P K AD R
Sbjct: 817 ELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFL-PG 875
Query: 754 SDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSS 813
DHL ++N + W E+ Y +C E F+ +++ +++ Q E LL V
Sbjct: 876 GDHLVLLNVYTQWAES-----GYSSQWCCENFVQFRSMRRARDVREQL-EGLLERVEVGL 929
Query: 814 RNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKS 873
S+ D ++ KA I AG + A RL R + K V +HP S
Sbjct: 930 -------SSCQGDYIRVRKA-ITAGYFYHTA--RLTRSGYRTV-----KQQQTVFIHPNS 974
Query: 874 VNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEVSPYCLL 911
EQ WL+YH + T+ ++ E+ LL
Sbjct: 975 SLFEQQP---RWLLYHELVLTTKEFMRQVLEIESSWLL 1009
Score = 154 bits (390), Expect = 3e-37
Identities = 105/335 (31%), Positives = 168/335 (50%), Gaps = 33/335 (9%)
Query: 60 REIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAP 119
R++ Y Q+ EA + HM + Q + ++ V+ ++ E Q W
Sbjct: 277 RDLAREYRAAGEQEKLEATNR----YHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEA 332
Query: 120 EDHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGT 179
+ ++ E K +L+ +E++ + + D E P T
Sbjct: 333 RLGAASLKFGARDAASQEPKY-----QLVLEEEETIEFVRATQLQGDEE---PSAPPTST 384
Query: 180 LDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQ 239
Q QK+ +Q R LP + ++EL+ I NHQV +I GETG GKTTQ
Sbjct: 385 QAQ------QKES-------IQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQ 431
Query: 240 VTQFILDN-YIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQS 298
+ Q++ + Y +G +I CTQPRR++A+SVA RVA E G N GY IR +
Sbjct: 432 IPQYLFEEGYTNKGM----KIACTQPRRVAAMSVAARVAREMGVKLG--NEVGYSIRFED 485
Query: 299 RLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRS 358
++ + Y T G++L+ S+P L+S S +++DE HER L +D+L ++KD+ FR
Sbjct: 486 -CTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRP 544
Query: 359 DLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPV 393
+LKV++ SAT++ +FS +F + P+ IPG FPV
Sbjct: 545 ELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPV 579
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo
sapiens]
Length = 707
Score = 167 bits (422), Expect = 6e-41
Identities = 117/391 (29%), Positives = 188/391 (48%), Gaps = 31/391 (7%)
Query: 491 ILVFLPGWDNISTLHDLLMSQVMFKSD---KFLIIPLHSLMPTVNQTQVFKRTPPGVRKI 547
ILVFL G + I + D L++PL++ +P Q +VF+ P G RK+
Sbjct: 291 ILVFLTGQEEIEAMSKTCRDIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKV 350
Query: 548 VIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQ 607
+I+TNIAETSITI + YV+D G +K ++ + + ++ + VSK A QR GRAGR
Sbjct: 351 IISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGRED 410
Query: 608 PGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAV 667
G CY LY D +PEI R L + LQ+ +++ + F M PS + +
Sbjct: 411 SGICYRLYTEDEFEKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTF--DFMSKPSPDHI 468
Query: 668 LLSIRHLMELNAL---DKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAAS 724
+I L L AL D Q LTP+G +A P+EP K IL F C + +LTI +
Sbjct: 469 QAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSL 528
Query: 725 LSFKDPFVIPLG-KEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWE 783
LS P +E++ R+K ++ + DH+T++N + + + KD+C E
Sbjct: 529 LSVDSVLHNPPSRREEVQGVRKKFISSE--GDHMTLLNIYRTF-----KNLGGNKDWCKE 581
Query: 784 YFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPKV 843
F++S + ++ ++ Q + L + + D ES ++ + L+
Sbjct: 582 NFVNSKNMTLVAEVRAQLRDICLKMSMPIASSRGDVES---------VRRCLAHSLFMST 632
Query: 844 AKIRLNLGKKRKMVKVYTKTDGLVAVHPKSV 874
A+++ + T T VA+HP SV
Sbjct: 633 AELQPD------GTYATTDTHQPVAIHPSSV 657
Score = 115 bits (288), Expect = 2e-25
Identities = 74/201 (36%), Positives = 114/201 (56%), Gaps = 14/201 (6%)
Query: 198 IEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSAC 257
+E+Q R LP + + +L+ + N V+ GETG GKTTQ+ Q++ + I R +G
Sbjct: 67 VELQ--RRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISR-QGI-- 121
Query: 258 RIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQ 317
I TQPRR++AIS+A RV+ E+ G GY +R + + I + T G++L+
Sbjct: 122 -IAVTQPRRVAAISLATRVSDEKRTELGK--LVGYTVRFDD-VTSEDTRIKFLTDGMLLR 177
Query: 318 WLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD-----LKVILMSATLNAE 372
SD L S ++LDE HER + +DVL VVK R + LKVI+MSAT++ +
Sbjct: 178 EAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVD 237
Query: 373 KFSEYFGNCPMIHIPGFTFPV 393
FS+YF P++++ G P+
Sbjct: 238 LFSQYFNGAPVLYLEGRQHPI 258
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 141 bits (356), Expect = 3e-33
Identities = 160/663 (24%), Positives = 280/663 (42%), Gaps = 104/663 (15%)
Query: 196 RYIEMQHFREKLPSYGMQKELVNLIDNHQ--VTVISGETGCGKTTQVTQFILDNYIERG- 252
RY E+ R+ LP + + + ++++ V ++SGE G GK+TQ+ Q+ + + RG
Sbjct: 34 RYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGF 93
Query: 253 -KGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCT 311
KG ++ TQP ++A S+A RVA E + G + GY I Q + +C
Sbjct: 94 QKG---QVTVTQPYPLAARSLALRVADEMDLTLG--HEVGYSIP-QEDCTGPNTLLRFCW 147
Query: 312 TGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKD--LLNFRSDLKVILMSATL 369
++LQ + S + +VLDE ER++ SD L +++D L DL+V++++
Sbjct: 148 DRLLLQEVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPA 207
Query: 370 NAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNR 429
K ++GN P++H + R
Sbjct: 208 LEPKLRAFWGNPPIVH-----------------------------------------IPR 226
Query: 430 QEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDG 489
+ E IY + P R A+ V+E+ +E G
Sbjct: 227 EPGERPSPIYWDTIPP------DRVEAACQAVLELCR------------------KELPG 262
Query: 490 AILVFLPGWDNISTLHDLLMSQV---MFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRK 546
+LVFLP + IS + L +V + + ++PLH P + RK
Sbjct: 263 DVLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLH---PDCGRAVQAVYEDMDARK 319
Query: 547 IVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRV 606
+V+ +A+ S ++ + +VID G + ++ + +SK A+ R+ RA
Sbjct: 320 VVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGF 379
Query: 607 QPGHCYHLYNGLRASL-LDDYQLPEILRTPLEELCLQIKILRLG--GIAYFLSRLMDPPS 663
PG C LY L P + L L L +K ++ G +FL D P+
Sbjct: 380 PPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFL----DQPA 435
Query: 664 NEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAA 723
EA++ ++ L L ALD +L+ LGV L+ P+ P + K +L F C+D +LT+AA
Sbjct: 436 PEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAA 495
Query: 724 SLSFKDPFV-IPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCW 782
L+ F PL E+ A R E T DH +++ +E + ++ ++ +C
Sbjct: 496 MLTAAPGFTRPPLSAEEAALRRALE---HTDGDHSSLIQVYEAFIQSGA-----DEAWCQ 547
Query: 783 EYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPK 842
L+ L H ++G+ E + P + + N + ++ + +G + K
Sbjct: 548 ARGLNWAALCQAHKLRGELLELMQRIEL-----PLSLPAFGSEQNRRDLQKALVSGYFLK 602
Query: 843 VAK 845
VA+
Sbjct: 603 VAR 605
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 119 bits (298), Expect = 1e-26
Identities = 159/731 (21%), Positives = 305/731 (41%), Gaps = 114/731 (15%)
Query: 196 RYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQ----FILDNYIER 251
RY ++ RE LP + + + + +Q+ ++SG+ CGK+ QV Q + L + +
Sbjct: 51 RYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQH 110
Query: 252 GKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCT 311
G ++CTQ + + + +A RVA E G+ GY I ++ CT
Sbjct: 111 GG-----VICTQVHKQTVVQLALRVADEM--DVNIGHEVGYVIPFEN----------CCT 153
Query: 312 TGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNA 371
IL++ D++ +R + S+ F VI++
Sbjct: 154 NETILRYCT-------------DDMLQREMMSNP----------FLGSYGVIILDD---- 186
Query: 372 EKFSEYFGNCPMIHIPGFTFPVVEYLLEDVI---EKIRYVPEQKEHRSQFKRGFMQGHVN 428
IH V+ LL+DV+ +++ + H K G+V
Sbjct: 187 ------------IHERSIATDVLLGLLKDVLLARPELKLIINSSPHLIS-KLNSYYGNVP 233
Query: 429 RQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEED 488
E + K V+V+ + E K I+ LI I E
Sbjct: 234 VIEVKNKHP---------------------VEVVYLSEAQKDSFESILRLIFEIHHSGEK 272
Query: 489 GAILVFLPGWDNISTLHDLLMSQVMFKSD--KFLIIPLH-----SLMPTVNQTQVFKRTP 541
G I+VFL +I + + + D + +++PL+ SL +++T+ KR
Sbjct: 273 GDIVVFLACEQDIEKVCETVYQGSNLNPDLGELVVVPLYPKEKCSLFKPLDETE--KRCQ 330
Query: 542 PGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKG 601
R++V+ T+ E I + V +VID G + ++ + +++ + +S++ A+ RK
Sbjct: 331 VYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQ 390
Query: 602 RAGRVQPGHCYHLYNGLRASL-LDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD 660
G G + LY AS + + E+ L + L +K + + G+ + M+
Sbjct: 391 ILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGH--CDFMN 448
Query: 661 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT 720
P+ E+++ ++ L L ALD L+ G+ ++ P++P + K IL F C+D VLT
Sbjct: 449 RPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLT 508
Query: 721 IAASLSFKDPFV-IPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRG---FRY 776
IAA ++ + F +P G E+ A K DH T+++ ++ +++ +
Sbjct: 509 IAAMVTAPNCFSHVPHGAEEAALTCWKTFL-HPEGDHFTLISIYKAYQDTTLNSSSEYCV 567
Query: 777 EKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVIC 836
EK +C +YFL+ + L+M ++ + E + P + + +N IK +
Sbjct: 568 EK-WCRDYFLNCSALRMADVIRAELLEIIKRIEL-----PYAEPAFGSKENTLNIKKALL 621
Query: 837 AGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSS 896
+G + ++A+ G + + +HP S T W+++H + +
Sbjct: 622 SGYFMQIARDVDGSGNYLMLTH-----KQVAQLHPLS-GYSITKKMPEWVLFHKFSISEN 675
Query: 897 IYLYDCTEVSP 907
Y+ +E+SP
Sbjct: 676 NYIRITSEISP 686
>gi|12056465 fibrillarin [Homo sapiens]
Length = 321
Score = 62.8 bits (151), Expect = 2e-09
Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Query: 12 DGGPRSSGGGYGGGPAGGHG----GNRGSGGGGGGGGGGRGGRGRHPGHLKGREIGMWYA 67
D G R GG+GGG G G G G GGGGGGGGGGRGG G H G +GR G
Sbjct: 20 DRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
Query: 68 KKQGQKNKEAERQERAVVHMDERREEQIV 96
+ G KN E V + +E+ +V
Sbjct: 80 NQSG-KNVMVEPHRHEGVFICRGKEDALV 107
Score = 53.1 bits (126), Expect = 1e-06
Identities = 28/56 (50%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGG--GRGGRGRHPGHLKGREIG 63
G GG R GGG+ G GG GG G GGGG GGGG G RGR G +G + G
Sbjct: 28 GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
Score = 51.6 bits (122), Expect = 4e-06
Identities = 27/53 (50%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREI 62
GR GG R G G GGG GG GG RG GG GG GR GRG G+ G+ +
Sbjct: 35 GRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGR-GRGGKRGNQSGKNV 86
Score = 32.7 bits (73), Expect = 1.8
Identities = 17/30 (56%), Positives = 17/30 (56%)
Query: 34 RGSGGGGGGGGGGRGGRGRHPGHLKGREIG 63
RG G GG GG G RGGRG G GR G
Sbjct: 8 RGGGFGGRGGFGDRGGRGGRGGFGGGRGRG 37
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 59.3 bits (142), Expect = 2e-08
Identities = 27/43 (62%), Positives = 27/43 (62%)
Query: 9 WGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRG 51
WG GG GGG GGG GG GG G GGGGGGGGG GG G
Sbjct: 338 WGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG 380
Score = 54.7 bits (130), Expect = 4e-07
Identities = 27/46 (58%), Positives = 28/46 (60%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPG 55
G GG R GG GGG GG GG G GGGGGGG GG GRG + G
Sbjct: 350 GGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGG 395
Score = 52.8 bits (125), Expect = 2e-06
Identities = 29/57 (50%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 9 WGRDGGPRSSGGGYGGGPAGGHGGNRG--SGGGGGGGGGGRGGRGRHPGHLKGREIG 63
WG GG GGG GGG GG GG RG G G GG GG GGRG + G G G
Sbjct: 359 WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYG 415
Score = 50.4 bits (119), Expect = 8e-06
Identities = 25/45 (55%), Positives = 25/45 (55%)
Query: 7 QNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRG 51
Q G G GGG GG GG GG RG GGGGGG GG GG G
Sbjct: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373
Score = 48.9 bits (115), Expect = 2e-05
Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 26/66 (39%)
Query: 9 WGRDGGPRSSGGGYGGGPAGGHGGNRGSG-----------------------GGGGGGGG 45
WG GG GGG+GGG GG GG +G G GGGGGGGG
Sbjct: 366 WGGGGG---GGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGG 422
Query: 46 GRGGRG 51
G GG G
Sbjct: 423 GGGGGG 428
Score = 46.6 bits (109), Expect = 1e-04
Identities = 27/49 (55%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGR---GGRGRHPG 55
G GG GGG+GGG GG GG G GGGG GG GR GGRG + G
Sbjct: 354 GGRGGWGGGGGGWGGGGGGG-GGWGGGGGGGRGGFQGRGDYGGRGGYGG 401
Score = 40.4 bits (93), Expect = 0.008
Identities = 20/30 (66%), Positives = 20/30 (66%), Gaps = 4/30 (13%)
Query: 23 GGGPAGGHGGNRGSGGGGGGGGGGRGGRGR 52
GGG GG GG GGGGGG GGG GG GR
Sbjct: 331 GGGGRGGWGG----GGGGGGRGGGGGGGGR 356
Score = 35.8 bits (81), Expect = 0.21
Identities = 18/38 (47%), Positives = 18/38 (47%)
Query: 4 DYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGG 41
DY G G G GYG GG GG G GGGGG
Sbjct: 392 DYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
Score = 30.8 bits (68), Expect = 6.7
Identities = 16/32 (50%), Positives = 16/32 (50%)
Query: 34 RGSGGGGGGGGGGRGGRGRHPGHLKGREIGMW 65
R GGGG GG GG GG G G G G W
Sbjct: 328 RQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGW 359
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 57.8 bits (138), Expect = 5e-08
Identities = 29/59 (49%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
Query: 3 YDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGG-RGRHPGHLKGR 60
Y ++ G GG R G GYGG +GG+GG+R GG GG GGG GG RG + G + GR
Sbjct: 519 YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 577
Score = 54.7 bits (130), Expect = 4e-07
Identities = 29/57 (50%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 3 YDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKG 59
Y ++ G GG RS GGGYGG GG+GG+RG G GG GGG G RG + G G
Sbjct: 434 YSGDRSGGGYGGDRS-GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGG 489
Score = 52.0 bits (123), Expect = 3e-06
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
Query: 3 YDYHQNWGRDGGPRSSGGGYGGG-PAGGHGGNRGSGGGGGGGGGGRGG-RGRHPGHLKGR 60
Y ++ G GG RSSGGGY G GG+GG+R GG GG GGG GG RG G +G
Sbjct: 415 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 474
Query: 61 EIG 63
G
Sbjct: 475 GYG 477
Score = 51.2 bits (121), Expect = 5e-06
Identities = 29/52 (55%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGG--GGGGGGGRGGRGRHPGHLKG 59
G GG R GGGYGG GG+GG+RG GG GGG GG RGG G G G
Sbjct: 458 GGYGGDR--GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 507
Score = 48.9 bits (115), Expect = 2e-05
Identities = 26/50 (52%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 11 RDGGPRSSGGGYGGGPAGGHGGNRGS-GGGGGGGGGGRGGRGRHPGHLKG 59
R GG GGYGG GG+GG+RG GG GG GG RGG G G G
Sbjct: 472 RGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGG 521
Score = 47.4 bits (111), Expect = 7e-05
Identities = 31/64 (48%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGG--GGGGGGRGGRGRHPGHLKGREIGMWYA 67
G GG R GGGYGG GG+GG+RG G GG GG GG RGG G G G G
Sbjct: 466 GGYGGDR--GGGYGGD-RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGD 522
Query: 68 KKQG 71
+ +G
Sbjct: 523 RSRG 526
Score = 47.0 bits (110), Expect = 9e-05
Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
Query: 10 GRDGGPRSSGGGYGG------GPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIG 63
G GG GGYGG G GG+GG+R GG GG GGG G G G G G
Sbjct: 493 GDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG 552
Query: 64 MWYAKKQG 71
Y +G
Sbjct: 553 GGYGGDRG 560
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/61 (45%), Positives = 32/61 (52%), Gaps = 8/61 (13%)
Query: 5 YHQNWGRDGGPRSSGGGYGG------GPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLK 58
Y + G GG R GGGYGG G GG+GG+RG GG GG GG RG + G
Sbjct: 476 YGGDRGGYGGDR--GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRG 533
Query: 59 G 59
G
Sbjct: 534 G 534
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/68 (44%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
Query: 13 GGPRSSGGGYGGGPAGG-HGGNRGSGGG------GGGGGGGR--GGRGRHPGHLKGREIG 63
GG GGYGG +GG +GG+R SGGG GGG GG R GG G G G + G
Sbjct: 406 GGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG 465
Query: 64 MWYAKKQG 71
Y +G
Sbjct: 466 GGYGGDRG 473
Score = 43.5 bits (101), Expect = 0.001
Identities = 26/58 (44%), Positives = 29/58 (50%), Gaps = 9/58 (15%)
Query: 11 RDGGPRSSGGGYGG------GPAGGHGGNRGSGGGG---GGGGGGRGGRGRHPGHLKG 59
R GG GGYGG G GG+GG+RG GG GG GG RGG + G G
Sbjct: 487 RGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSG 544
Score = 40.8 bits (94), Expect = 0.006
Identities = 30/59 (50%), Positives = 33/59 (55%), Gaps = 7/59 (11%)
Query: 10 GRDGGPRSSGGGYGG--GPAGGHGGNRGSGGGGGG---GGGGRGGRGRHPGHLKGREIG 63
G GG RS GGGYGG GG+ G+R SGGG GG GGG G RG G +G G
Sbjct: 413 GGYGGDRS-GGGYGGDRSSGGGYSGDR-SGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 469
Score = 38.5 bits (88), Expect = 0.032
Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 7/60 (11%)
Query: 11 RDGGPRSSGGGYGGGPA----GGHGGNRGSGGG---GGGGGGGRGGRGRHPGHLKGREIG 63
R G G GYGG GG GG+RG GG GGG GG R G + G G G
Sbjct: 385 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 444
Score = 38.1 bits (87), Expect = 0.042
Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 5/67 (7%)
Query: 7 QNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGG--GGGGGRGGRGRHPGHLKGREIGM 64
+ +G + G R GG GG GG+GG+R GG GG GGG G R G G G
Sbjct: 394 RGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYGGDRSSGGGYSG-DRSGGGYGGDRSGG 450
Query: 65 WYAKKQG 71
Y +G
Sbjct: 451 GYGGDRG 457
Score = 36.2 bits (82), Expect = 0.16
Identities = 22/47 (46%), Positives = 23/47 (48%), Gaps = 3/47 (6%)
Query: 8 NWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGG---GGGGGGRGGRG 51
N R R SGG + G GG G RG GG G GG GG R G G
Sbjct: 377 NEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGG 423
Score = 32.7 bits (73), Expect = 1.8
Identities = 17/31 (54%), Positives = 18/31 (58%), Gaps = 1/31 (3%)
Query: 19 GGGYGGGPAGGHGGNRGSGGGGGGGGGGRGG 49
GGG GGG G GG RG GG G GG + G
Sbjct: 324 GGGSGGGRRG-RGGYRGRGGFQGRGGDPKSG 353
Score = 32.0 bits (71), Expect = 3.0
Identities = 19/48 (39%), Positives = 20/48 (41%), Gaps = 2/48 (4%)
Query: 9 WGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGH 56
+G D R GG GGG G G G G GG RGG GH
Sbjct: 167 YGEDN--RGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGH 212
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 57.8 bits (138), Expect = 5e-08
Identities = 29/59 (49%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
Query: 3 YDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGG-RGRHPGHLKGR 60
Y ++ G GG R G GYGG +GG+GG+R GG GG GGG GG RG + G + GR
Sbjct: 522 YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 580
Score = 54.7 bits (130), Expect = 4e-07
Identities = 29/57 (50%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 3 YDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKG 59
Y ++ G GG RS GGGYGG GG+GG+RG G GG GGG G RG + G G
Sbjct: 437 YSGDRSGGGYGGDRS-GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGG 492
Score = 52.0 bits (123), Expect = 3e-06
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
Query: 3 YDYHQNWGRDGGPRSSGGGYGGG-PAGGHGGNRGSGGGGGGGGGGRGG-RGRHPGHLKGR 60
Y ++ G GG RSSGGGY G GG+GG+R GG GG GGG GG RG G +G
Sbjct: 418 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 477
Query: 61 EIG 63
G
Sbjct: 478 GYG 480
Score = 51.2 bits (121), Expect = 5e-06
Identities = 29/52 (55%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGG--GGGGGGGRGGRGRHPGHLKG 59
G GG R GGGYGG GG+GG+RG GG GGG GG RGG G G G
Sbjct: 461 GGYGGDR--GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 510
Score = 48.9 bits (115), Expect = 2e-05
Identities = 26/50 (52%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 11 RDGGPRSSGGGYGGGPAGGHGGNRGS-GGGGGGGGGGRGGRGRHPGHLKG 59
R GG GGYGG GG+GG+RG GG GG GG RGG G G G
Sbjct: 475 RGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGG 524
Score = 47.4 bits (111), Expect = 7e-05
Identities = 31/64 (48%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGG--GGGGGGRGGRGRHPGHLKGREIGMWYA 67
G GG R GGGYGG GG+GG+RG G GG GG GG RGG G G G G
Sbjct: 469 GGYGGDR--GGGYGGD-RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGD 525
Query: 68 KKQG 71
+ +G
Sbjct: 526 RSRG 529
Score = 47.0 bits (110), Expect = 9e-05
Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
Query: 10 GRDGGPRSSGGGYGG------GPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIG 63
G GG GGYGG G GG+GG+R GG GG GGG G G G G G
Sbjct: 496 GDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG 555
Query: 64 MWYAKKQG 71
Y +G
Sbjct: 556 GGYGGDRG 563
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/61 (45%), Positives = 32/61 (52%), Gaps = 8/61 (13%)
Query: 5 YHQNWGRDGGPRSSGGGYGG------GPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLK 58
Y + G GG R GGGYGG G GG+GG+RG GG GG GG RG + G
Sbjct: 479 YGGDRGGYGGDR--GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRG 536
Query: 59 G 59
G
Sbjct: 537 G 537
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/68 (44%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
Query: 13 GGPRSSGGGYGGGPAGG-HGGNRGSGGG------GGGGGGGR--GGRGRHPGHLKGREIG 63
GG GGYGG +GG +GG+R SGGG GGG GG R GG G G G + G
Sbjct: 409 GGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG 468
Query: 64 MWYAKKQG 71
Y +G
Sbjct: 469 GGYGGDRG 476
Score = 43.5 bits (101), Expect = 0.001
Identities = 26/58 (44%), Positives = 29/58 (50%), Gaps = 9/58 (15%)
Query: 11 RDGGPRSSGGGYGG------GPAGGHGGNRGSGGGG---GGGGGGRGGRGRHPGHLKG 59
R GG GGYGG G GG+GG+RG GG GG GG RGG + G G
Sbjct: 490 RGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSG 547
Score = 40.8 bits (94), Expect = 0.006
Identities = 30/59 (50%), Positives = 33/59 (55%), Gaps = 7/59 (11%)
Query: 10 GRDGGPRSSGGGYGG--GPAGGHGGNRGSGGGGGG---GGGGRGGRGRHPGHLKGREIG 63
G GG RS GGGYGG GG+ G+R SGGG GG GGG G RG G +G G
Sbjct: 416 GGYGGDRS-GGGYGGDRSSGGGYSGDR-SGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 472
Score = 38.5 bits (88), Expect = 0.032
Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 7/60 (11%)
Query: 11 RDGGPRSSGGGYGGGPA----GGHGGNRGSGGG---GGGGGGGRGGRGRHPGHLKGREIG 63
R G G GYGG GG GG+RG GG GGG GG R G + G G G
Sbjct: 388 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 447
Score = 38.1 bits (87), Expect = 0.042
Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 5/67 (7%)
Query: 7 QNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGG--GGGGGRGGRGRHPGHLKGREIGM 64
+ +G + G R GG GG GG+GG+R GG GG GGG G R G G G
Sbjct: 397 RGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYGGDRSSGGGYSG-DRSGGGYGGDRSGG 453
Query: 65 WYAKKQG 71
Y +G
Sbjct: 454 GYGGDRG 460
Score = 36.2 bits (82), Expect = 0.16
Identities = 22/47 (46%), Positives = 23/47 (48%), Gaps = 3/47 (6%)
Query: 8 NWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGG---GGGGGGRGGRG 51
N R R SGG + G GG G RG GG G GG GG R G G
Sbjct: 380 NEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGG 426
Score = 32.7 bits (73), Expect = 1.8
Identities = 17/31 (54%), Positives = 18/31 (58%), Gaps = 1/31 (3%)
Query: 19 GGGYGGGPAGGHGGNRGSGGGGGGGGGGRGG 49
GGG GGG G GG RG GG G GG + G
Sbjct: 327 GGGSGGGRRG-RGGYRGRGGFQGRGGDPKSG 356
Score = 32.0 bits (71), Expect = 3.0
Identities = 19/48 (39%), Positives = 20/48 (41%), Gaps = 2/48 (4%)
Query: 9 WGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGH 56
+G D R GG GGG G G G G GG RGG GH
Sbjct: 170 YGEDN--RGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGH 215
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 56.2 bits (134), Expect = 1e-07
Identities = 62/224 (27%), Positives = 98/224 (43%), Gaps = 38/224 (16%)
Query: 10 GRDGGPRSS----GGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIGMW 65
G GG SS GGG+GGG GG GG GSG GG GG GG G G G L E
Sbjct: 99 GASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGG-GAGGGDGGILTANE---- 153
Query: 66 YAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPEDHGYG 125
K+ E R ++D+ VQ L +A ND E++ Q W+ + G
Sbjct: 154 -------KSTMQELNSRLASYLDK------VQALE--EANNDLENKIQ-DWYDKK----G 193
Query: 126 TEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQEN-----EPDGTL 180
KN N +D + ++++ + N++ +D D+ + ++ E + L
Sbjct: 194 PAAIQKNYSPYYNTIDDLKDQIVD----LTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNL 249
Query: 181 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQ 224
Q + D+ + L + M+ ++ +Q+EL+ L NH+
Sbjct: 250 RQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHK 293
Score = 55.1 bits (131), Expect = 3e-07
Identities = 26/47 (55%), Positives = 27/47 (57%)
Query: 13 GGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKG 59
GG SGG YG G GG GG+ G GG GGG GGG G RG G G
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGG 522
Score = 52.8 bits (125), Expect = 2e-06
Identities = 30/63 (47%), Positives = 30/63 (47%), Gaps = 17/63 (26%)
Query: 10 GRDGGPRSSGGGYGGGPAGGH----------------GGNRGSGGGGGGG-GGGRGGRGR 52
G G SGGGYGGG GGH GG GSGGG GGG GGG G RG
Sbjct: 522 GGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGG 581
Query: 53 HPG 55
G
Sbjct: 582 SGG 584
Score = 51.2 bits (121), Expect = 5e-06
Identities = 23/46 (50%), Positives = 25/46 (54%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPG 55
G GG G G GGG GG+GG G G GG GGG GG G + G
Sbjct: 514 GGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYG 559
Score = 50.4 bits (119), Expect = 8e-06
Identities = 27/52 (51%), Positives = 29/52 (55%), Gaps = 6/52 (11%)
Query: 10 GRDGGPRS--SGGGYGGGPAGGHGGNRGSGGGG----GGGGGGRGGRGRHPG 55
G GG S SGGG+ GG G +GG GSGGG GGG G RGG G G
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHG 587
Score = 50.1 bits (118), Expect = 1e-05
Identities = 28/60 (46%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 10 GRDGGPRSSGGGYGGGPA------GGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIG 63
G G SGGGYGGG G +GG GSGGG GGG GG G G G G G
Sbjct: 494 GGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGG 553
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/56 (50%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNR--GSGGGGGGGGGGRGGRGRHPGHLKGREIG 63
G GG SGGG GGG GG GG GSGGG GG GG G G G G G
Sbjct: 518 GSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573
Score = 49.3 bits (116), Expect = 2e-05
Identities = 23/46 (50%), Positives = 24/46 (52%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPG 55
G GG G G GGG GG+GG GS GG GG GG G G G
Sbjct: 552 GGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESG 597
Score = 48.5 bits (114), Expect = 3e-05
Identities = 27/58 (46%), Positives = 28/58 (48%)
Query: 2 SYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKG 59
SY + G GG S GG GG GG G GSGGG GGG GG G GH G
Sbjct: 496 SYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGG 553
Score = 46.6 bits (109), Expect = 1e-04
Identities = 23/40 (57%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGG 49
G G SGGGYGGG +G GG+ GS GGG G GG GG
Sbjct: 560 GGSGSGGGSGGGYGGG-SGSRGGSGGSHGGGSGFGGESGG 598
Score = 46.2 bits (108), Expect = 2e-04
Identities = 25/49 (51%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 8 NWGRDGGPRSSGGGYGGGPAG-GHGGNRGSGGGGGGGGGGRGGRGRHPG 55
++GR G SGG YGGG +G G+GG GS GG GG GG G G G
Sbjct: 484 SYGR-GSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSG 531
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGG-GGGGGGGRGGRGRHPGHLKGREIGMWYAK 68
G GG SGGG GGG GG G GSGG GGG G G G + G + G Y
Sbjct: 556 GNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGG 615
Query: 69 KQGQKN 74
G+ +
Sbjct: 616 GSGKSS 621
Score = 44.7 bits (104), Expect = 4e-04
Identities = 24/53 (45%), Positives = 25/53 (47%), Gaps = 3/53 (5%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGG---GGGRGGRGRHPGHLKG 59
G G SGG YGGG G G G GGG GGG G G G G G+ G
Sbjct: 508 GGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGG 560
Score = 44.3 bits (103), Expect = 6e-04
Identities = 28/58 (48%), Positives = 28/58 (48%), Gaps = 4/58 (6%)
Query: 10 GRDGGPRSS--GGGYGGGPAGGHGGNRGSGG--GGGGGGGGRGGRGRHPGHLKGREIG 63
G GG S GGG GGG GG G GSGG GGG G GG G G G G G
Sbjct: 488 GSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGG 545
Score = 38.9 bits (89), Expect = 0.025
Identities = 28/62 (45%), Positives = 30/62 (48%), Gaps = 12/62 (19%)
Query: 10 GRDGGPRSSGGGYGGGPAG----GHGGNRGS--GGGGGGG------GGGRGGRGRHPGHL 57
G GG SS GYGGG + G GG+ G GGG GGG GGG GG R G
Sbjct: 41 GGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGA 100
Query: 58 KG 59
G
Sbjct: 101 SG 102
Score = 37.7 bits (86), Expect = 0.055
Identities = 23/53 (43%), Positives = 23/53 (43%), Gaps = 6/53 (11%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGG------GGGRGGRGRHPGH 56
G GG S GG GG GG G SGG GGG GGG GG H
Sbjct: 570 GGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSH 622
Score = 37.4 bits (85), Expect = 0.072
Identities = 22/44 (50%), Positives = 25/44 (56%), Gaps = 4/44 (9%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGN--RGSGGGGGG--GGGGRGG 49
G++ S G G G GG GG+ RGS GG GG GGGG GG
Sbjct: 461 GQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGG 504
Score = 37.0 bits (84), Expect = 0.094
Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 14 GPRSSGGGYGGGPAGGHG-GNRGSGGGGGGGGGGRGGRGRHPGHLKG 59
G G G GG G +G G+RG GG GGGG GG G G G
Sbjct: 469 GAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG 515
Score = 35.8 bits (81), Expect = 0.21
Identities = 26/67 (38%), Positives = 26/67 (38%), Gaps = 12/67 (17%)
Query: 17 SSGGGYGGGPAGGHGGNRGS----GGGGGGGGGGR--------GGRGRHPGHLKGREIGM 64
S GG GGG G G R S GGGGGGGR GG R G G G
Sbjct: 12 SRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71
Query: 65 WYAKKQG 71
Y G
Sbjct: 72 SYGGGSG 78
Score = 34.7 bits (78), Expect = 0.46
Identities = 22/43 (51%), Positives = 24/43 (55%), Gaps = 10/43 (23%)
Query: 17 SSGGGYGGG---PAGGHGGNR----GSGGGGGGG---GGGRGG 49
SSGGG GGG + G+GG G GGGG G GGG GG
Sbjct: 37 SSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79
Score = 31.2 bits (69), Expect = 5.1
Identities = 17/42 (40%), Positives = 18/42 (42%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRG 51
G G RSS + GG GG S G GGG GRG
Sbjct: 23 GSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRG 64
Score = 30.4 bits (67), Expect = 8.8
Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 3/44 (6%)
Query: 17 SSGGGYGGGPAGGHGGNRGS-GGGGGGGGGGRGGRGRHPGHLKG 59
SSG G G GG GG+ GS G G GG GG G G G G
Sbjct: 467 SSGAGKIG--LGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGG 508
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 55.5 bits (132), Expect = 3e-07
Identities = 29/49 (59%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
Query: 6 HQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHP 54
H G GGP GGG GGGP GG GG G GGGGGG GGG G HP
Sbjct: 144 HDGPGGGGGP-GGGGGPGGGPGGGGGG--GPGGGGGGPGGGLLGGSAHP 189
Score = 50.4 bits (119), Expect = 8e-06
Identities = 23/37 (62%), Positives = 23/37 (62%)
Query: 13 GGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGG 49
GG G G GGGP GG G G GGGGGGG GG GG
Sbjct: 140 GGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGG 176
Score = 47.8 bits (112), Expect = 5e-05
Identities = 25/41 (60%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
Query: 10 GRDGGPRSSGG-GYGGGPAGGHGGNRGSGGGGGGGGGGRGG 49
G GP GG G GGGP GG GG G GG GGGGGG GG
Sbjct: 142 GAHDGPGGGGGPGGGGGPGGGPGGG-GGGGPGGGGGGPGGG 181
Score = 46.6 bits (109), Expect = 1e-04
Identities = 24/50 (48%), Positives = 26/50 (52%)
Query: 14 GPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIG 63
G + GGG GP GG G G G GGG GGGG GG G G G +G
Sbjct: 135 GAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLG 184
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 5/48 (10%)
Query: 13 GGPRSSGGGYGGGPAGGHGGNRGSGGGG-----GGGGGGRGGRGRHPG 55
GG ++ GG G G GG G GGG GGGGGG GG G PG
Sbjct: 132 GGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPG 179
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/70 (45%), Positives = 37/70 (52%), Gaps = 14/70 (20%)
Query: 8 NWGRDGGPRSSGGGYGGG----------PAGGHG----GNRGSGGGGGGGGGGRGGRGRH 53
N+G+D SSGGG GGG +GG+G G RG GG GGGGGGG GG R
Sbjct: 176 NYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRS 235
Query: 54 PGHLKGREIG 63
G + R G
Sbjct: 236 SGGYEPRGRG 245
Score = 49.7 bits (117), Expect = 1e-05
Identities = 26/45 (57%), Positives = 27/45 (60%), Gaps = 4/45 (8%)
Query: 11 RDGGPRSSGGGYGGGPAGGHGGNRGSGG----GGGGGGGGRGGRG 51
+D G R GG GGG GG G NR SGG G GGG GGRGG G
Sbjct: 211 QDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMG 255
Score = 46.6 bits (109), Expect = 1e-04
Identities = 29/71 (40%), Positives = 36/71 (50%), Gaps = 12/71 (16%)
Query: 2 SYDYHQNWGRDGGPRSSGGGYGGGPAGGHGG----NRGSGGGGGG--------GGGGRGG 49
SY+ Q +G+ SS GG GGG GG+ G + SGGG GG GGGG GG
Sbjct: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGG 207
Query: 50 RGRHPGHLKGR 60
G+ +GR
Sbjct: 208 YGQQDRGGRGR 218
Score = 45.1 bits (105), Expect = 3e-04
Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 5/56 (8%)
Query: 4 DYHQNWGRDGGPRSSGG-----GYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHP 54
D+++ G G R GG GYGGG +GG G GGGGGGG R G + P
Sbjct: 374 DFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCP 429
Score = 41.6 bits (96), Expect = 0.004
Identities = 28/61 (45%), Positives = 29/61 (47%), Gaps = 10/61 (16%)
Query: 10 GRDGGPRSS--GGGYGGGPAGG-----HGGNRGSGGGGGGGGGGRGGRGR---HPGHLKG 59
G GGP S GG YG GG GG RG GG GG GGRGG R PG +
Sbjct: 454 GPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDS 513
Query: 60 R 60
R
Sbjct: 514 R 514
Score = 38.5 bits (88), Expect = 0.032
Identities = 20/45 (44%), Positives = 23/45 (51%)
Query: 15 PRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKG 59
P GGG GG GG+ G+ GG GG GG GRG G +G
Sbjct: 452 PDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
Score = 36.2 bits (82), Expect = 0.16
Identities = 23/54 (42%), Positives = 25/54 (46%), Gaps = 5/54 (9%)
Query: 2 SYDYHQNWGRDGGPRSSGGGYGG--GPAGGHGGNRGSGGGGGGGGGGRGGRGRH 53
+Y + GR G R GGY G G GG G RG G GG G G RG H
Sbjct: 467 NYGDDRRGGRGGYDR---GGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517
Score = 35.4 bits (80), Expect = 0.27
Identities = 22/48 (45%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGG----GGGRGGRGRH 53
G G RSSGG G GG GG G GG GG GG R RH
Sbjct: 228 GGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRH 275
Score = 35.0 bits (79), Expect = 0.36
Identities = 21/54 (38%), Positives = 21/54 (38%), Gaps = 10/54 (18%)
Query: 3 YDYHQNWGRDGGPRSSGGGYGGG----------PAGGHGGNRGSGGGGGGGGGG 46
Y GR G GGG GGG P G GG G GG GG GG
Sbjct: 208 YGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261
Score = 33.5 bits (75), Expect = 1.0
Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 1 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGH-GGN--------RGSGGGGG--GGGGGRGG 49
M++ + + P+ G G GGP G H GGN RG GG G GG RGG
Sbjct: 436 MNFSWRNECNQCKAPKPDGPG--GGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGG 493
Query: 50 -RGRHPGHLKGREIGMWYAKKQGQKNKEAERQER 82
RG G +G G K + +R+ER
Sbjct: 494 FRGGRGGGDRG---GFGPGKMDSRGEHRQDRRER 524
Score = 32.7 bits (73), Expect = 1.8
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 4/53 (7%)
Query: 2 SYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNR--GSGGGGGGGGGGRGGRGR 52
SY ++G G +S G P G+G S GGGGGGGG G G+
Sbjct: 129 SYSQQPSYG--GQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQ 179
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 54.7 bits (130), Expect = 4e-07
Identities = 26/43 (60%), Positives = 28/43 (65%), Gaps = 1/43 (2%)
Query: 10 GRDGGPRSSGGGYGGGPA-GGHGGNRGSGGGGGGGGGGRGGRG 51
G G SSGGGYGGG + GGHGG+ G GGG GGG GG G
Sbjct: 501 GGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYG 543
Score = 54.3 bits (129), Expect = 6e-07
Identities = 26/50 (52%), Positives = 27/50 (54%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKG 59
G GG S GG GGG GGHGG+ G G GGG GGG G G G G
Sbjct: 471 GGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSG 520
Score = 52.0 bits (123), Expect = 3e-06
Identities = 29/60 (48%), Positives = 31/60 (51%), Gaps = 8/60 (13%)
Query: 10 GRDGGPRSSGGGYGGGPA------GGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIG 63
GR GG S GGGYGGG + GGHGG G GGG GGG GG G+ G G
Sbjct: 463 GRGGG--SFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSG 520
Score = 50.4 bits (119), Expect = 8e-06
Identities = 26/57 (45%), Positives = 27/57 (47%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIGMWY 66
G GG GG +GGG GG G SGGG GGG GG G G G G G Y
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513
Score = 50.4 bits (119), Expect = 8e-06
Identities = 25/48 (52%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSG-GGGGGGGGGRGGRGRHPGH 56
G G SSGGG+GGG G GG G G GGG GGG GG GH
Sbjct: 475 GGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGH 522
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/53 (45%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 10 GRDGGPRSSGG---GYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKG 59
G GG S GG G+GG GG+GG GG GGG GG G H G G
Sbjct: 476 GSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSG 528
Score = 44.7 bits (104), Expect = 4e-04
Identities = 24/54 (44%), Positives = 27/54 (50%)
Query: 8 NWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGRE 61
++G G GG +GGG GG G GGGG GGG GG G G L G E
Sbjct: 93 SFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNE 146
Score = 44.7 bits (104), Expect = 4e-04
Identities = 24/52 (46%), Positives = 25/52 (48%)
Query: 12 DGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIG 63
+G S GGG GGG GG G SGGG GGG G G G G G G
Sbjct: 454 EGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG 505
Score = 41.2 bits (95), Expect = 0.005
Identities = 24/49 (48%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLK 58
G GG GG +GGG GG GG G G GGG GGG G G G+ K
Sbjct: 100 GSFGGGSFGGGSFGGGSFGG-GGFGGGGFGGGFGGGFGGDGGLLSGNEK 147
Score = 40.0 bits (92), Expect = 0.011
Identities = 21/44 (47%), Positives = 22/44 (50%)
Query: 2 SYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGG 45
SY G GG GG +GGG GG G G GGG GG GG
Sbjct: 97 SYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGG 140
Score = 39.7 bits (91), Expect = 0.014
Identities = 55/235 (23%), Positives = 92/235 (39%), Gaps = 34/235 (14%)
Query: 17 SSGGGYGGGPAGGHGGNRGSGGG-------------------GGG--GGGGRGGRGRHPG 55
SSGGG GG +GG+GG G GGG GGG GGG GG G
Sbjct: 61 SSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGG 120
Query: 56 HLKGREIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQA--KNDKESEAQ 113
G G + G E+ + + +++ L+ V+A +++ E E +
Sbjct: 121 GFGGGGFGGGFGGGFGGDGGLLSGNEKVTM---QNLNDRLASYLDKVRALEESNYELEGK 177
Query: 114 I-SWFAPEDHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIR---NRSYIDRDSEY 169
I W+ E HG + ++ +D + +++N I + + + D
Sbjct: 178 IKEWY--EKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFR 235
Query: 170 LLQENEPDGTLDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQ 224
L ENE L Q + D+ + L + + ++ + +EL L NH+
Sbjct: 236 LKYENEV--ALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHE 288
Score = 37.7 bits (86), Expect = 0.055
Identities = 20/41 (48%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Query: 17 SSGGGYGGGPAGGHGGNRGSGGGG--GGGGGGRGGRGRHPG 55
S GGG+ G G +RGS GGG GG GG GG G G
Sbjct: 42 SLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGG 82
Score = 36.6 bits (83), Expect = 0.12
Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 11/57 (19%)
Query: 18 SGGGYGGGPAGGHGG--------NRGSGGGG---GGGGGGRGGRGRHPGHLKGREIG 63
SGGG GGG GG GG ++GS GGG GG GG RG G G G
Sbjct: 16 SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSG 72
Score = 35.8 bits (81), Expect = 0.21
Identities = 20/42 (47%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Query: 16 RSSGGGYGGGPAGGHGGNRGSGGGGGG-GGGGRGGRGRHPGH 56
RS G G GG GG GG GGG GGG G G GH
Sbjct: 450 RSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGH 491
Score = 35.0 bits (79), Expect = 0.36
Identities = 16/33 (48%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 13 GGPRSSGGGYGGGPAGGHGGNRGS-GGGGGGGG 44
G GGGYGGG +GG + G GGG GG
Sbjct: 533 GSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGG 565
Score = 34.3 bits (77), Expect = 0.61
Identities = 21/42 (50%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRG 51
G GG SSGG GG + G G G GG GG GG GG G
Sbjct: 41 GSLGGGFSSGGFSGGSFSRGSSGG-GCFGGSSGGYGGLGGFG 81
Score = 32.0 bits (71), Expect = 3.0
Identities = 21/42 (50%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 10 GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRG 51
G GG S G GGG GG G G G GG GGG RG G
Sbjct: 51 GFSGGSFSRGSS-GGGCFGGSSGGYG-GLGGFGGGSFRGSYG 90
Score = 31.2 bits (69), Expect = 5.1
Identities = 12/20 (60%), Positives = 14/20 (70%)
Query: 30 HGGNRGSGGGGGGGGGGRGG 49
+ +R GGGGGGG GG GG
Sbjct: 11 YSSSRSGGGGGGGGCGGGGG 30
Score = 30.8 bits (68), Expect = 6.7
Identities = 13/20 (65%), Positives = 14/20 (70%)
Query: 30 HGGNRGSGGGGGGGGGGRGG 49
H + SGGGGGGGG G GG
Sbjct: 10 HYSSSRSGGGGGGGGCGGGG 29
Score = 30.4 bits (67), Expect = 8.8
Identities = 18/46 (39%), Positives = 19/46 (41%), Gaps = 13/46 (28%)
Query: 17 SSGGGYGGGPAGGHGGNRGSGGGGG-------------GGGGGRGG 49
SS Y +GG GG G GGGGG GGG GG
Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGG 51
>gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo
sapiens]
Length = 3258
Score = 53.5 bits (127), Expect = 1e-06
Identities = 24/37 (64%), Positives = 24/37 (64%)
Query: 13 GGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGG 49
GGP SG G GGG GG G G GG GGGGGGG GG
Sbjct: 730 GGPAVSGAGDGGGEEGGGGDGGGGGGDGGGGGGGGGG 766
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/35 (62%), Positives = 22/35 (62%), Gaps = 7/35 (20%)
Query: 12 DGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGG 46
DGG GGG GGG GG G GGGGGGGGGG
Sbjct: 739 DGGGEEGGGGDGGG--GG-----GDGGGGGGGGGG 766
Score = 39.3 bits (90), Expect = 0.019
Identities = 40/151 (26%), Positives = 59/151 (39%), Gaps = 20/151 (13%)
Query: 17 SSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGREIGMWYAKKQGQKNKE 76
SS G+GG G G G GGGG GGGG G G G G Y K +K
Sbjct: 724 SSTCGFGGPAVSGAGDGGGEEGGGGDGGGGGGDGGGGGGGGGGP-----YEK----NDKN 774
Query: 77 AERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPEDHGYGTEVSTKNTPCS 136
E+ E V +++++ S+ ++ E H + ++
Sbjct: 775 QEKDESTPVSNHRLALTMLIKIVKSLGC----------AYGCGEGHRGLSGDRLRHQVFR 824
Query: 137 ENKLDIQEKKLINQEKKMFRIRNRSYIDRDS 167
EN + KL +K FR R Y+++DS
Sbjct: 825 ENAQNCL-TKLYKLDKMQFRQTMRDYVNKDS 854
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,810,073
Number of Sequences: 37866
Number of extensions: 1958430
Number of successful extensions: 33076
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 443
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 15524
Number of HSP's gapped (non-prelim): 8060
length of query: 1008
length of database: 18,247,518
effective HSP length: 112
effective length of query: 896
effective length of database: 14,006,526
effective search space: 12549847296
effective search space used: 12549847296
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.