Guide to the Human Genome
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Search of human proteins with 166795299

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166795299 solute carrier family 2 (facilitated glucose transp...   968   0.0  
gi|4507011 glucose transporter 4 [Homo sapiens]                       641   0.0  
gi|5902090 solute carrier family 2 (facilitated glucose transpor...   635   0.0  
gi|23592238 glucose transporter 14 [Homo sapiens]                     618   e-177
gi|4557851 solute carrier family 2 (facilitated glucose transpor...   540   e-153
gi|4507013 solute carrier family 2 (facilitated glucose/fructose...   393   e-109
gi|134053883 intestinal facilitative glucose transporter 7 [Homo...   380   e-105
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ...   365   e-101
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ...   365   e-101
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi...   320   2e-87
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]   320   2e-87
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]   318   7e-87
gi|21361449 solute carrier family 2 (facilitated glucose transpo...   185   9e-47
gi|207447703 solute carrier family 2 (facilitated glucose/fructo...   167   2e-41
gi|223029432 solute carrier family 2 (facilitated glucose transp...   160   2e-39
gi|203098995 solute carrier family 2 (facilitated glucose transp...   150   2e-36
gi|223029430 solute carrier family 2 (facilitated glucose transp...   150   3e-36
gi|21553331 solute carrier family 2 (facilitated glucose transpo...   125   9e-29
gi|13540547 solute carrier family 2 member 10 [Homo sapiens]           99   1e-20
gi|24497490 solute carrier family 22 member 4 [Homo sapiens]           69   7e-12
gi|11415038 solute carrier family 22 member 3 [Homo sapiens]           65   1e-10
gi|4507005 solute carrier family 22 member 5 [Homo sapiens]            65   1e-10
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa...    64   4e-10
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    61   3e-09
gi|238814326 solute carrier family 22, member 20 [Homo sapiens]        60   5e-09
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa...    60   5e-09
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa...    60   6e-09
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            58   2e-08
gi|166197673 solute carrier family 22, member 15 [Homo sapiens]        54   3e-07
gi|24497499 solute carrier family 22 member 8 [Homo sapiens]           54   4e-07

>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score =  968 bits (2503), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT 60
           MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
Sbjct: 1   MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT 60

Query: 61  LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120
           LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
Sbjct: 61  LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120

Query: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180
           MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
Sbjct: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180

Query: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240
           GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
Sbjct: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240

Query: 241 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK 300
           LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
Sbjct: 241 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK 300

Query: 301 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360
           AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
Sbjct: 301 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360

Query: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420
           LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
Sbjct: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420

Query: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE 480
           CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
Sbjct: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE 480

Query: 481 ELFHPLGADSQV 492
           ELFHPLGADSQV
Sbjct: 481 ELFHPLGADSQV 492


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score =  641 bits (1653), Expect = 0.0
 Identities = 323/493 (65%), Positives = 395/493 (80%), Gaps = 5/493 (1%)

Query: 2   EPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYG----ESIL 57
           EP  +++TG L+LAV  AVLGSLQFGYN GVINAPQKVIE+ YN+TW+ R G     SI 
Sbjct: 14  EPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIP 73

Query: 58  PTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGK 117
           P TLTTLW+LSVAIFSVGGMI SF +G+     GR+ +ML+ N+LA +   LMG +    
Sbjct: 74  PGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAA 133

Query: 118 SFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLD 177
           S+EMLILGRF+IG Y GLT+G VPMYVGE++PT LRGALGTL+QL IV+GILIAQV GL+
Sbjct: 134 SYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLE 193

Query: 178 SIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADV 237
           S++G   LWPLLL +  +PALLQ ++LPFCPESPR+L I +N E  A+  LK+L G ADV
Sbjct: 194 SLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADV 253

Query: 238 THDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSI 297
           +  L E+K+E R++ RE+ +++L+L  S  +RQP++IAVVLQLSQQLSGINAVFYYSTSI
Sbjct: 254 SGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSI 313

Query: 298 FEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALAL 357
           FE AGV QP YATIG+G+VNT FT+VS+ +VERAGRRTLHL+GLAGM GCAILMT+AL L
Sbjct: 314 FETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLL 373

Query: 358 LEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFI 417
           LE++P MSY+SIVAIFGFVAFFE+GPGPIPWFIVAELFSQGPRPAA+AVAGFSNWTSNFI
Sbjct: 374 LERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFI 433

Query: 418 VGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGF-RQGGASQSD 476
           +GM FQYV +  GPYVF++F VLL+ FFIFT+ +VPET+GRTFD+I++ F R     + +
Sbjct: 434 IGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQE 493

Query: 477 KTPEELFHPLGAD 489
             P      LG D
Sbjct: 494 VKPSTELEYLGPD 506


>gi|5902090 solute carrier family 2 (facilitated glucose
           transporter), member 3 [Homo sapiens]
          Length = 496

 Score =  635 bits (1639), Expect = 0.0
 Identities = 314/477 (65%), Positives = 386/477 (80%), Gaps = 1/477 (0%)

Query: 5   SKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTL 64
           ++K+T  L+ A+  A +GS QFGYNTGVINAP+K+I+EF N+T   +         LT+L
Sbjct: 3   TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSL 62

Query: 65  WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLIL 124
           WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML++NLLA      MG  K+ KS EMLIL
Sbjct: 63  WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLIL 122

Query: 125 GRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKD 184
           GR +IG++CGL TGFVPMY+GE+SPTALRGA GTL+QLGIVVGIL+AQ+FGL+ I+G+++
Sbjct: 123 GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEE 182

Query: 185 LWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEM 244
           LWPLLL    +PA+LQ   LPFCPESPRFLLINR EE  AK +L++L GT DV+ D+QEM
Sbjct: 183 LWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEM 242

Query: 245 KEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ 304
           K+ES +M +EK+VT+LELFR  +YRQPI+I++VLQLSQQLSGINAVFYYST IF+ AGVQ
Sbjct: 243 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 302

Query: 305 QPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWM 364
           +P+YATIG+G+VNT FTVVSLF+VERAGRRTLH+IGL GMA C+ LMT++L L +    M
Sbjct: 303 EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGM 362

Query: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424
           S++ I AI  FVAFFE+GPGPIPWFIVAELFSQGPRPAA+AVAG SNWTSNF+VG+ F  
Sbjct: 363 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 422

Query: 425 VEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEE 481
                G YVFIIFT  L+ F  FT+FKVPET+GRTF++I   F +G A  +D++ ++
Sbjct: 423 AAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF-EGQAHGADRSGKD 478


>gi|23592238 glucose transporter 14 [Homo sapiens]
          Length = 520

 Score =  618 bits (1593), Expect = e-177
 Identities = 306/481 (63%), Positives = 381/481 (79%), Gaps = 1/481 (0%)

Query: 1   MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT 60
           M+P +  +T  L+ A+  A +GS QFGYNTGVINAP+ +I+EF N+T   +         
Sbjct: 23  MKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVL 82

Query: 61  LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120
           LT LWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML++NLLA     LMG  K+ +S E
Sbjct: 83  LTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVE 142

Query: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180
           MLILGR +IG++CGL TGFVPMY+GE+SPTALRGA GTL+QLGIV+GIL+AQ+FGL+ I+
Sbjct: 143 MLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELIL 202

Query: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240
           G+++LWP+LL    +PA+LQ   LP CPESPRFLLINR +E  A  +L++L GT DV+ D
Sbjct: 203 GSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQD 262

Query: 241 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK 300
           +QEMK+ES +M +EK+VT+LELFR  +YRQPI+I++VLQLSQQLSGINAVFYYST IF+ 
Sbjct: 263 IQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKD 322

Query: 301 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360
           AGVQQP+YATI +G+VNT FT++SLF+VERAGRRTLH+IGL GMA C+ LMT++L L   
Sbjct: 323 AGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNH 382

Query: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420
              MS++ I AI  FVA FE+GPGPIPWFIVAELFSQGPRPAA+AVAG SNWTSNF+VG+
Sbjct: 383 YNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGL 442

Query: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE 480
            F       G YVFIIFT  L+ F  FT+FKVPET+GRTF++I   F +G A  +D++ +
Sbjct: 443 LFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF-EGQAHGADRSGK 501

Query: 481 E 481
           +
Sbjct: 502 D 502


>gi|4557851 solute carrier family 2 (facilitated glucose
           transporter), member 2 [Homo sapiens]
          Length = 524

 Score =  540 bits (1391), Expect = e-153
 Identities = 274/511 (53%), Positives = 364/511 (71%), Gaps = 35/511 (6%)

Query: 7   KLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFY---------NQTWVHRY---GE 54
           K+TG L+  V  AVLGS QFGY+ GVINAPQ+VI   Y         ++  ++ Y     
Sbjct: 5   KVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINST 64

Query: 55  SILPT----------------------TLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGR 92
             LPT                       +T LWSLSV+ F+VGGM  SF  G   +  GR
Sbjct: 65  DELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGR 124

Query: 93  RNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTAL 152
             +ML+ N+L+ V A+LMGFSKLG S  ++I GR I G+YCGL +G VPMY+GE++PTAL
Sbjct: 125 IKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTAL 184

Query: 153 RGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPR 212
           RGALGT HQL IV GILI+Q+ GL+ I+GN DLW +LL +  + A+LQ ++L FCPESPR
Sbjct: 185 RGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPR 244

Query: 213 FLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPI 272
           +L I  +EE +AK  LK+LRG  DVT D+ EM++E  +   E+KV+I++LF + +YRQPI
Sbjct: 245 YLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPI 304

Query: 273 LIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAG 332
           L+A++L ++QQ SGIN +FYYSTSIF+ AG+ +PVYATIG G VN  FT VS+F+VE+AG
Sbjct: 305 LVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAG 364

Query: 333 RRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVA 392
           RR+L LIG++GM  CAI M++ L LL +  WMSY+S++AIF FV+FFE+GPGPIPWF+VA
Sbjct: 365 RRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVA 424

Query: 393 ELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKV 452
           E FSQGPRPAA+A+A FSNWT NFIV +CFQY+   CGPYVF +F  +L+ F +FT+FKV
Sbjct: 425 EFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKV 484

Query: 453 PETKGRTFDEIASGF-RQGGASQSDKTPEEL 482
           PETKG++F+EIA+ F ++ G++   K   E+
Sbjct: 485 PETKGKSFEEIAAEFQKKSGSAHRPKAAVEM 515


>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 501

 Score =  393 bits (1009), Expect = e-109
 Identities = 198/461 (42%), Positives = 296/461 (64%), Gaps = 7/461 (1%)

Query: 10  GRLMLAVGGAVL-----GSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTL 64
           GRL L +  A L      S Q+GYN   +N+P  ++++FYN+T+  R GE +    LT L
Sbjct: 11  GRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLL 70

Query: 65  WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLIL 124
           WS++V++F  GG IGS  VG  VN+FGR+ ++L  N+ + V A+LMG S++  SFE++I+
Sbjct: 71  WSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIII 130

Query: 125 GRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKD 184
            R ++G+  G+++  VPMY+GE++P  LRGALG + QL I VGIL+AQ+FGL +++ N D
Sbjct: 131 SRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVD 190

Query: 185 LWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEM 244
            WP+LL +  +PA LQ ++LPF PESPR+LLI + +E  AK  L+ LRG   V  ++ E+
Sbjct: 191 GWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEI 250

Query: 245 KEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV- 303
           ++E         +++L+LFR  + R  +L  +VL   QQLSG+NA++YY+  I+  AGV 
Sbjct: 251 RQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVP 310

Query: 304 -QQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLP 362
            +   Y T G+G VN   T  ++FVVE  GRR L L+G +       ++T ALAL + + 
Sbjct: 311 EEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVS 370

Query: 363 WMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCF 422
           WM Y+SIV +  +V    +GP PIP  ++ E+F Q  RP+A  V G  +W SNF VG+ F
Sbjct: 371 WMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIF 430

Query: 423 QYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEI 463
            ++++  GPY FI+F V+ +L  I+ +  VPETK +TF EI
Sbjct: 431 PFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEI 471


>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
           sapiens]
          Length = 512

 Score =  380 bits (977), Expect = e-105
 Identities = 191/478 (39%), Positives = 298/478 (62%), Gaps = 6/478 (1%)

Query: 7   KLTGRLMLAVGGAVLGS-LQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLW 65
           +L   L+LA   A  GS  Q+GYN  V+N P KV + FYN+T+  R+   +    +  LW
Sbjct: 18  RLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLW 77

Query: 66  SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILG 125
           S +V++F +GG++GS  VGL V+  GR+ ++L+ N+ A + A+LMG SK+ K+FE+++  
Sbjct: 78  SCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFS 137

Query: 126 RFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDL 185
           R ++GV  G++   +PMY+GE++P  LRG +GT+ ++ ++VG+ +AQ+F L +I+GN   
Sbjct: 138 RVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAG 197

Query: 186 WPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMK 245
           WP+LL++  +PALLQ + LPF PESPR+ LI + +E  A+  L++LRG  D+  +L++M+
Sbjct: 198 WPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMR 257

Query: 246 EESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ- 304
            E+R    E  +++L L    + R  +L  +VL   QQLSGINA+ YY+ +I+  AGV+ 
Sbjct: 258 AEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEA 317

Query: 305 -QPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPW 363
               Y T+GSG+VN   T+ S  +VER GRR L L G        +++T+ L    ++P 
Sbjct: 318 AHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPE 377

Query: 364 MSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQ 423
           +SYL I+ +F ++A   +GP P+P  +  E+F Q  R AA  V G  +W +NFI+G  F 
Sbjct: 378 LSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFP 437

Query: 424 YVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEE 481
            +++  G Y FIIF  + +L  I+ Y  +PETKG+TF EI   F +       K PEE
Sbjct: 438 SIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAK---RNRVKLPEE 492


>gi|47933389 solute carrier family 2, member 9 protein isoform 2
           [Homo sapiens]
          Length = 511

 Score =  365 bits (936), Expect = e-101
 Identities = 188/484 (38%), Positives = 289/484 (59%), Gaps = 7/484 (1%)

Query: 12  LMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAI 71
           L+ ++ GA   S  +GYN  V+NAP   I+ FYN++W  R+G  I P TLT LWS++V+I
Sbjct: 28  LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 87

Query: 72  FSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGV 131
           F++GG++G+  V +     GR++++L  N  A  +A+LM  S    +FEMLI+GRFI+G+
Sbjct: 88  FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 147

Query: 132 YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLS 191
             G+    +PMY+ E+SP  +RG+LG +  + I +G+   Q+ GL  ++G +  WP L  
Sbjct: 148 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 207

Query: 192 IIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQM 251
           +I +PA++Q + LPF P+SPR+LL+ ++ E RA    +   G ADV+ +++E+  ESR  
Sbjct: 208 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 267

Query: 252 MREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV--QQPVYA 309
              + V++LEL R+P  R  ++  +V     QL G+NA+++Y+ SIF KAG+   +  Y 
Sbjct: 268 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 327

Query: 310 TIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAI-LMTIALALLEQLPWMSYLS 368
           T+ +G + T   V S  V+E  GRR L LIG  G+ G     +TI L L +  PW+ YLS
Sbjct: 328 TLSTGGIETLAAVFSGLVIEHLGRRPL-LIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 386

Query: 369 IVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQL 428
           IV I   +A F  GPG IP+ +  E F Q  RPAA  +AG  NW SNF VG+ F ++++ 
Sbjct: 387 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 446

Query: 429 CGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGA 488
              Y F++F  + +   I+ YF +PETK RT+ EI+  F +   +     PEE       
Sbjct: 447 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAY---PPEEKIDSAVT 503

Query: 489 DSQV 492
           D ++
Sbjct: 504 DGKI 507


>gi|47933387 solute carrier family 2, member 9 protein isoform 1
           [Homo sapiens]
          Length = 540

 Score =  365 bits (936), Expect = e-101
 Identities = 188/484 (38%), Positives = 289/484 (59%), Gaps = 7/484 (1%)

Query: 12  LMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAI 71
           L+ ++ GA   S  +GYN  V+NAP   I+ FYN++W  R+G  I P TLT LWS++V+I
Sbjct: 57  LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 116

Query: 72  FSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGV 131
           F++GG++G+  V +     GR++++L  N  A  +A+LM  S    +FEMLI+GRFI+G+
Sbjct: 117 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 176

Query: 132 YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLS 191
             G+    +PMY+ E+SP  +RG+LG +  + I +G+   Q+ GL  ++G +  WP L  
Sbjct: 177 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 236

Query: 192 IIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQM 251
           +I +PA++Q + LPF P+SPR+LL+ ++ E RA    +   G ADV+ +++E+  ESR  
Sbjct: 237 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 296

Query: 252 MREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV--QQPVYA 309
              + V++LEL R+P  R  ++  +V     QL G+NA+++Y+ SIF KAG+   +  Y 
Sbjct: 297 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 356

Query: 310 TIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAI-LMTIALALLEQLPWMSYLS 368
           T+ +G + T   V S  V+E  GRR L LIG  G+ G     +TI L L +  PW+ YLS
Sbjct: 357 TLSTGGIETLAAVFSGLVIEHLGRRPL-LIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415

Query: 369 IVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQL 428
           IV I   +A F  GPG IP+ +  E F Q  RPAA  +AG  NW SNF VG+ F ++++ 
Sbjct: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475

Query: 429 CGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGA 488
              Y F++F  + +   I+ YF +PETK RT+ EI+  F +   +     PEE       
Sbjct: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAY---PPEEKIDSAVT 532

Query: 489 DSQV 492
           D ++
Sbjct: 533 DGKI 536


>gi|190684655 glucose transporter protein 10 isoform a [Homo
           sapiens]
          Length = 503

 Score =  320 bits (819), Expect = 2e-87
 Identities = 174/471 (36%), Positives = 267/471 (56%), Gaps = 7/471 (1%)

Query: 1   MEPSSKKLT---GRLMLAV--GGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGES 55
           +EPS +  T   GR++L       + G+ QFGYN  +INAP   I+EF N+TW  R GE 
Sbjct: 5   LEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 64

Query: 56  ILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKL 115
           +    +  +WSL V+++ +GG+ G+   G      GR+ S+L+ N+    +A+L GFS+ 
Sbjct: 65  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 124

Query: 116 GKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFG 175
             SFEM++LGR ++GV  G++    PMY+GE +P  LRGA+     +   +GI++ QV G
Sbjct: 125 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 184

Query: 176 LDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTA 235
           L  ++G    WPLLL+   +P  LQ   LP  PESPR+LLI+  +     + L++LRG+ 
Sbjct: 185 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 244

Query: 236 DVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYST 295
           D+  +L+E++EE       +     ELF+  A R+ +   VVL  + +L G ++V+ Y++
Sbjct: 245 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 304

Query: 296 SIFEKAGVQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI 353
           S+F KAGV +    YA IG+G       VVS  V+ER GRR L + G + M     + T+
Sbjct: 305 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 364

Query: 354 ALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWT 413
           AL L    PW  YL++  IF F+  F +GP  +   +  ELF Q  RPAA  V G   W 
Sbjct: 365 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 424

Query: 414 SNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464
              +VG+ F ++ +    ++++ F  + V   I+T   +PETKG+TF EI+
Sbjct: 425 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEIS 475


>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
          Length = 499

 Score =  320 bits (819), Expect = 2e-87
 Identities = 171/464 (36%), Positives = 264/464 (56%), Gaps = 4/464 (0%)

Query: 5   SKKLTGRLMLAV--GGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLT 62
           S+ + GR++L       + G+ QFGYN  +INAP   I+EF N+TW  R GE +    + 
Sbjct: 8   SRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVL 67

Query: 63  TLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEML 122
            +WSL V+++ +GG+ G+   G      GR+ S+L+ N+    +A+L GFS+   SFEM+
Sbjct: 68  LMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI 127

Query: 123 ILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGN 182
           +LGR ++GV  G++    PMY+GE +P  LRGA+     +   +GI++ QV GL  ++G 
Sbjct: 128 MLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGG 187

Query: 183 KDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQ 242
              WPLLL+   +P  LQ   LP  PESPR+LLI+  +     + L++LRG+ D+  +L+
Sbjct: 188 PQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELE 247

Query: 243 EMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAG 302
           E++EE       +     ELF+  A R+ +   VVL  + +L G ++V+ Y++S+F KAG
Sbjct: 248 ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG 307

Query: 303 VQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360
           V +    YA IG+G       VVS  V+ER GRR L + G + M     + T+AL L   
Sbjct: 308 VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSS 367

Query: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420
            PW  YL++  IF F+  F +GP  +   +  ELF Q  RPAA  V G   W    +VG+
Sbjct: 368 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 427

Query: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464
            F ++ +    ++++ F  + V   I+T   +PETKG+TF EI+
Sbjct: 428 GFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEIS 471


>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
          Length = 496

 Score =  318 bits (815), Expect = 7e-87
 Identities = 171/468 (36%), Positives = 264/468 (56%), Gaps = 4/468 (0%)

Query: 1   MEPSSKKLTGRLMLAV--GGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILP 58
           M    + + GR++L       + G+ QFGYN  +INAP   I+EF N+TW  R GE +  
Sbjct: 1   MRALRRLIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD 60

Query: 59  TTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKS 118
             +  +WSL V+++ +GG+ G+   G      GR+ S+L+ N+    +A+L GFS+   S
Sbjct: 61  HLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGS 120

Query: 119 FEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDS 178
           FEM++LGR ++GV  G++    PMY+GE +P  LRGA+     +   +GI++ QV GL  
Sbjct: 121 FEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRE 180

Query: 179 IMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVT 238
           ++G    WPLLL+   +P  LQ   LP  PESPR+LLI+  +     + L++LRG+ D+ 
Sbjct: 181 LLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLA 240

Query: 239 HDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIF 298
            +L+E++EE       +     ELF+  A R+ +   VVL  + +L G ++V+ Y++S+F
Sbjct: 241 GELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVF 300

Query: 299 EKAGVQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALA 356
            KAGV +    YA IG+G       VVS  V+ER GRR L + G + M     + T+AL 
Sbjct: 301 RKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALC 360

Query: 357 LLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNF 416
           L    PW  YL++  IF F+  F +GP  +   +  ELF Q  RPAA  V G   W    
Sbjct: 361 LQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLI 420

Query: 417 IVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464
           +VG+ F ++ +    ++++ F  + V   I+T   +PETKG+TF EI+
Sbjct: 421 LVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEIS 468


>gi|21361449 solute carrier family 2 (facilitated glucose
           transporter), member 8 [Homo sapiens]
          Length = 477

 Score =  185 bits (469), Expect = 9e-47
 Identities = 139/483 (28%), Positives = 235/483 (48%), Gaps = 59/483 (12%)

Query: 11  RLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVA 70
           R+ LA   A LG L FG+  G  +     ++                P       S   A
Sbjct: 25  RVFLAAFAAALGPLSFGFALGYSSPAIPSLQR----------AAPPAPRLDDAAASWFGA 74

Query: 71  IFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE--MLILGRFI 128
           + ++G   G    G  V+R GR+ S+L+ ++  FV+    GF+ +  + +  ML+ GR +
Sbjct: 75  VVTLGAAAGGVLGGWLVDRAGRKLSLLLCSV-PFVA----GFAVITAAQDVWMLLGGRLL 129

Query: 129 IGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFG--LDSIMGNKDLW 186
            G+ CG+ +   P+Y+ E++  A+RG LG+  QL +VVGIL+A + G  L+        W
Sbjct: 130 TGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE--------W 181

Query: 187 PLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKE 246
             L  +  +P  L  +++ F PE+PRFLL  ++    A + L+ L G+     D     E
Sbjct: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLL-TQHRRQEAMAALRFLWGSEQGWEDPPIGAE 240

Query: 247 ESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQP 306
           +S           L L R P   +P +I V L   QQLSG+NAV +Y+ +IFE+A  +  
Sbjct: 241 QSFH---------LALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDS 291

Query: 307 VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLI---------------------GLAGMA 345
             A++  G++   FT V+  +++RAGRR L ++                     G    +
Sbjct: 292 SLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSS 351

Query: 346 GCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIA 405
             AI   ++   ++    +++L++ ++  F+A F VG GPIPW +++E+F    +  A  
Sbjct: 352 HVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATG 411

Query: 406 VAGFSNWTSNFIVGMCFQYVEQLCGPY-VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464
           +   +NW   F+V   F  + ++  PY  F + +   +   +FT F VPETKG+T ++I 
Sbjct: 412 ICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQIT 471

Query: 465 SGF 467
           + F
Sbjct: 472 AHF 474


>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 244

 Score =  167 bits (424), Expect = 2e-41
 Identities = 81/180 (45%), Positives = 123/180 (68%), Gaps = 5/180 (2%)

Query: 10  GRLMLAVGGAVL-----GSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTL 64
           GRL L +  A L      S Q+GYN   +N+P  ++++FYN+T+  R GE +    LT L
Sbjct: 11  GRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLL 70

Query: 65  WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLIL 124
           WS++V++F  GG IGS  VG  VN+FGR+ ++L  N+ + V A+LMG S++  SFE++I+
Sbjct: 71  WSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIII 130

Query: 125 GRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKD 184
            R ++G+  G+++  VPMY+GE++P  LRGALG + QL I VGIL+AQ+FGL +++ N D
Sbjct: 131 SRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVD 190


>gi|223029432 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 1 [Homo sapiens]
          Length = 507

 Score =  160 bits (406), Expect = 2e-39
 Identities = 142/495 (28%), Positives = 225/495 (45%), Gaps = 59/495 (11%)

Query: 11  RLMLAVGGAVLGSLQFGY----NTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWS 66
           R+ LA   AVLG+  FGY     + VI A ++ ++              +  T     W 
Sbjct: 37  RVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDP------------DLHLTKSQASWF 84

Query: 67  LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGR 126
            SV  F++G   G  S  +  +  GR+ S++   + +     LM  +       ML+LGR
Sbjct: 85  GSV--FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAH---GLWMLLLGR 139

Query: 127 FIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLW 186
            + G   GLT   +P+YV E++P  +RGALG   QL  V G L     GL         W
Sbjct: 140 TLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL------LLPW 193

Query: 187 PLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGT-ADVTHDLQEMK 245
             L      P L+  ++L F P SPRFLL +R  +  A   L  LRGT  DV  + ++++
Sbjct: 194 RWLAVAGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQ 252

Query: 246 EESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQ 305
           +  R+  +  +V+  E  R+P   +PI +A++++L QQL+GI  +  Y  SIF+   V  
Sbjct: 253 DNVRR--QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLL 309

Query: 306 PVYATIG-SGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI----------- 353
           P        G V     +++   ++ AGR+ L  +  A M    + + +           
Sbjct: 310 PPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSP 369

Query: 354 -ALALLEQLPW----------MSYLSIVAIFG---FVAFFEVGPGPIPWFIVAELFSQGP 399
            + A LE   W            YL++V +     F+  + VG GPI W +++E+     
Sbjct: 370 NSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRA 429

Query: 400 RPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYV-FIIFTVLLVLFFIFTYFKVPETKGR 458
           R  A  +   ++W + F++   F  V    G  V F  F  + ++  +FT   VPETKGR
Sbjct: 430 RGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGR 489

Query: 459 TFDEIASGFRQGGAS 473
           + ++I S FR G  S
Sbjct: 490 SLEQIESFFRTGRRS 504


>gi|203098995 solute carrier family 2 (facilitated glucose
           transporter), member 13 [Homo sapiens]
          Length = 648

 Score =  150 bits (380), Expect = 2e-36
 Identities = 101/350 (28%), Positives = 172/350 (49%), Gaps = 26/350 (7%)

Query: 19  AVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMI 78
           + LG   FGY+TGV++    +++                  +L  LW   +   +VG   
Sbjct: 88  SALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDALWQELLVSSTVGAAA 132

Query: 79  GSFSVGLFVNR-FGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTT 137
            S   G  +N  FGRR ++L+ + L    + ++  +    + E L+ GR ++G+  G+ +
Sbjct: 133 VSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN---NKETLLAGRLVVGLGIGIAS 189

Query: 138 GFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPA 197
             VP+Y+ EVSP  LRG L T++ L I  G   A V         KD W  +L +  +PA
Sbjct: 190 MTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPA 249

Query: 198 LLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMK---EESRQMMRE 254
           ++Q     F PESPR+ LI + +  +A+ +L ++RG   +  +   +K   EE  + +  
Sbjct: 250 VIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGS 308

Query: 255 KKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQ---PVYATI 311
               I  +   P  R+ +++   LQ+ QQLSGIN + YYS +I + +GV+     ++   
Sbjct: 309 AGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLAS 368

Query: 312 GSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQL 361
            +   N  FT+V +++VE+ GRR L    LAG     I++ +   L  Q+
Sbjct: 369 VTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQV 418



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 5/118 (4%)

Query: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424
           S+ +++ +  ++ FF  G GP+PW + +E++    R    A +   NW  N +V + F +
Sbjct: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565

Query: 425 VEQLCGPY-VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQG----GASQSDK 477
             +    Y  F ++     +  +F Y  +PETKG+  +EI S F       G S SD+
Sbjct: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDE 623


>gi|223029430 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 2 [Homo sapiens]
          Length = 445

 Score =  150 bits (379), Expect = 3e-36
 Identities = 134/470 (28%), Positives = 209/470 (44%), Gaps = 71/470 (15%)

Query: 11  RLMLAVGGAVLGSLQFGY----NTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWS 66
           R+ LA   AVLG+  FGY     + VI A ++ ++              +  T     W 
Sbjct: 37  RVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDP------------DLHLTKSQASWF 84

Query: 67  LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGR 126
            SV  F++G   G  S  +  +  GR+ S++   + +     LM  +       ML+LGR
Sbjct: 85  GSV--FTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAH---GLWMLLLGR 139

Query: 127 FIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLW 186
            + G   GLT   +P+YV E++P  +RGALG   QL  V G L     GL         W
Sbjct: 140 TLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL------LLPW 193

Query: 187 PLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGT-ADVTHDLQEMK 245
             L      P L+  ++L F P SPRFLL +R  +  A   L  LRGT  DV  + ++++
Sbjct: 194 RWLAVAGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQ 252

Query: 246 EESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQ 305
           +  R+  +  +V+  E  R+P   +PI +A++++L QQL+GI  +  Y  SIF+   V  
Sbjct: 253 DNVRR--QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLL 309

Query: 306 PVYATIG-SGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWM 364
           P        G V     +++   ++ AGR+ L                            
Sbjct: 310 PPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLL--------------------------- 342

Query: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424
                     FV+ + VG GPI W +++E+     R  A  +   ++W + F++   F  
Sbjct: 343 ----------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLP 392

Query: 425 VEQLCGPYV-FIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGAS 473
           V    G  V F  F  + ++  +FT   VPETKGR+ ++I S FR G  S
Sbjct: 393 VVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRS 442


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score =  125 bits (314), Expect = 9e-29
 Identities = 86/292 (29%), Positives = 156/292 (53%), Gaps = 18/292 (6%)

Query: 69  VAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMN-LLAFVSAVLMGFSKLGKSFEMLILGRF 127
           V+   +G ++ S + G+ ++R+GRR ++++ + LL   S VL+    L  S+ +LI+GR 
Sbjct: 83  VSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLI----LSLSYTVLIVGRI 138

Query: 128 IIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQV--FGLDSIMGNKDL 185
            IGV   L++    +Y+ E++P   RG L +L++L IV+GIL A +  +   ++      
Sbjct: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHG--- 195

Query: 186 WPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMK 245
           W  +  ++    +LQ I + F P SPRFL++ + +E  A  VL +LR  +D T +L  +K
Sbjct: 196 WKYMFGLVIPLGVLQAIAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDTTEELTVIK 254

Query: 246 EESRQMMREKKVTILELFRS-PAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ 304
              +    E + +  +LFRS    R  I+I + L    Q++G   + +Y++++ +  G Q
Sbjct: 255 SSLKD---EYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQ 311

Query: 305 QPVYATI---GSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI 353
               A++   G G+V    T+ +  +V+  G +T   IG + MA   + M I
Sbjct: 312 SNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 34/103 (33%), Positives = 63/103 (61%), Gaps = 1/103 (0%)

Query: 363 WMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCF 422
           ++ +LS+ ++  +VA F +G GP+PW +++E+F  G R  A+A+    NW  N ++ + F
Sbjct: 459 FLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTF 518

Query: 423 QYVEQLCG-PYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464
             V  L G P+V  I+T++ +   +F    +PETKG + ++I+
Sbjct: 519 LTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561


>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
          Length = 541

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 90/338 (26%), Positives = 149/338 (44%), Gaps = 41/338 (12%)

Query: 12  LMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAI 71
           L L    ++LG L FGY   VI+     ++  +  + + +                 V  
Sbjct: 8   LPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQ--------------EFLVGS 53

Query: 72  FSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGV 131
             +G ++ S   G  ++ +GR+ ++L  NL+    ++ +G   L  S   L+LGR ++G 
Sbjct: 54  LLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAVVGF 110

Query: 132 YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLS 191
              L++    +YV E+     RG L +L++ GI VGIL++      ++ G    W  +  
Sbjct: 111 AISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY-ALAGTPWGWRHMFG 169

Query: 192 IIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQM 251
               PA+LQ + L F P           +E      L  L+G            E  +  
Sbjct: 170 WATAPAVLQSLSLLFLPAG--------TDETATHKDLIPLQGG-----------EAPKLG 210

Query: 252 MREKKVTILELFRS-PAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV---QQPV 307
               + + L+LFR+    R    + + L L QQL+G   V  Y+++IF   G       V
Sbjct: 211 PGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAV 270

Query: 308 YATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMA 345
            A++G G V  A T+ ++ +V+RAGRR L L G A MA
Sbjct: 271 LASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMA 308



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 1/107 (0%)

Query: 364 MSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQ 423
           + + +++ +  FV+ F  G GP+ W +++E++    R  A A     NW +N  + + F 
Sbjct: 408 LRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFL 467

Query: 424 YVEQLCG-PYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQ 469
            +    G  + F+++ +  VL   F Y  VPETKG++  EI   F++
Sbjct: 468 DLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQK 514


>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
          Length = 551

 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 105/453 (23%), Positives = 189/453 (41%), Gaps = 52/453 (11%)

Query: 52  YGESILPTTLTTLWSL----------SVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNL 101
           + + +  +T+ T W+L          + ++F VG ++GSF  G   +RFGR+      N+
Sbjct: 119 FSQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRK------NV 172

Query: 102 LAFVSAVLMGFSKL---GKSFEMLILGRFIIGVYCGLTTGFVPMYV--GEVSPTALRGAL 156
           L    AV  GFS L     S+EM  +   I+G+  G  + +V  ++   E+   ++R   
Sbjct: 173 LFATMAVQTGFSFLQIFSISWEMFTVLFVIVGM--GQISNYVVAFILGTEILGKSVRIIF 230

Query: 157 GTLHQLG-IVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLL 215
            TL       VG ++  +F        +D W +LL  + +P +L   +  F PESPR+L+
Sbjct: 231 STLGVCTFFAVGYMLLPLFAYFI----RD-WRMLLLALTVPGVLCVPLWWFIPESPRWLI 285

Query: 216 INRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIA 275
             R        + K  +        +     E    ++++K  IL+LFR+        IA
Sbjct: 286 SQRRFREAEDIIQKAAKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRN------IA 339

Query: 276 VVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYAT-IGSGIVNTAFTVVSLFVVERAGRR 334
           ++  +S  L  + +V Y++ S+ +   +    Y     S ++     + +  ++    RR
Sbjct: 340 IMTIMSLLLWMLTSVGYFALSL-DAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRR 398

Query: 335 TLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAEL 394
             ++I      G  +L+ I L  ++       L ++  FG  + F      + +   AEL
Sbjct: 399 --YIIAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFS-----MLYVFTAEL 451

Query: 395 FSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPE 454
           +    R  A+ V   ++   + I+   F Y+        +I+   L VL  I T F  PE
Sbjct: 452 YPTLVRNMAVGVTSTASRVGS-IIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLF-FPE 509

Query: 455 TKGRTFDEI------ASGFRQGGASQSDKTPEE 481
           + G T  E          FR G  ++     EE
Sbjct: 510 SLGMTLPETLEQMQKVKWFRSGKKTRDSMETEE 542


>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
          Length = 556

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 104/436 (23%), Positives = 184/436 (42%), Gaps = 74/436 (16%)

Query: 67  LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGR 126
           L+ AI ++G + G+F++G   +R+GR    L+  L   V+ V++ F+    +F + ++ R
Sbjct: 156 LTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFA---PNFPVFVIFR 212

Query: 127 FIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLW 186
           F+ GV+   T     + V E+  +  R  +G + Q+   +GI+I    G+   + N   W
Sbjct: 213 FLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILP--GIAYFIPN---W 267

Query: 187 PLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLR--GTADVTHDLQEM 244
             +   I +P+ L  +     PESPR+ LI R + ++A  +L+++       ++ +  E+
Sbjct: 268 QGIQLAITLPSFLFLLYYWVVPESPRW-LITRKKGDKALQILRRIAKCNGKYLSSNYSEI 326

Query: 245 KEESRQMMREKKVTILELFRSPAYRQPILI--------AVVLQ-LSQQLSGINAVFYYST 295
                ++      + L+L R+P  R+  LI        AVV Q L  +L  I    Y   
Sbjct: 327 TVTDEEV---SNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDF 383

Query: 296 SIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIAL 355
            I               SG+V     ++ L  +ER GRR L       +AG A L+T  L
Sbjct: 384 FI---------------SGVVELPGALLILLTIERLGRR-LPFAASNIVAGVACLVTAFL 427

Query: 356 ALLEQLPWM-SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTS 414
              E + W+ + ++ +   G    FE     I + + +EL+    R              
Sbjct: 428 P--EGIAWLRTTVATLGRLGITMAFE-----IVYLVNSELYPTTLR-------------- 466

Query: 415 NFIVGMCFQYVE--QLCGPYVFIIFTVL-----LVLFFIFT------YFKVPETKGRTFD 461
           NF V +C    +   +  P++      +     L++F I           +PETKG    
Sbjct: 467 NFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALP 526

Query: 462 EIASGFRQGGASQSDK 477
           E      + G+  S K
Sbjct: 527 ETVDDVEKLGSPHSCK 542


>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
          Length = 557

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 100/452 (22%), Positives = 198/452 (43%), Gaps = 58/452 (12%)

Query: 52  YGESILPTTLTTLWSL----------SVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNL 101
           + + +  +T+ T W+L          ++++F VG ++GSF  G   +RFGR+      N+
Sbjct: 119 FSQDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRK------NV 172

Query: 102 LAFVSAVLMGFSKL---GKSFEMLILGRFIIGVYCGLTTGFVPMYV--GEVSPTALRGAL 156
           L     +  GFS L    K+FEM ++   ++G+  G  + +V  +V   E+   ++R   
Sbjct: 173 LFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGM--GQISNYVAAFVLGTEILGKSVRIIF 230

Query: 157 GTLHQLGIVVGILIAQVFG---LDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRF 213
            TL       G+ I   FG   L         W +LL  + +P +L   +  F PESPR+
Sbjct: 231 STL-------GVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRW 283

Query: 214 LLINRNEENRAKSVLKKLRGTADVT-----HDLQEMKEESRQMMREKKVTILELFRSPAY 268
            LI++     A+ +++K      +       D  E+++ S +  +++   IL+L R+   
Sbjct: 284 -LISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSK--KQQSHNILDLLRTWNI 340

Query: 269 RQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYAT-IGSGIVNTAFTVVSLFV 327
           R   +++++L ++       +V Y+  S+ +   +   ++     S +V     V++  +
Sbjct: 341 RMVTIMSIMLWMT------ISVGYFGLSL-DTPNLHGDIFVNCFLSAMVEVPAYVLAWLL 393

Query: 328 VERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIP 387
           ++   RR  + +  A   G ++L+ + L   +     + L +V  FG  A F      + 
Sbjct: 394 LQYLPRR--YSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFS-----MV 446

Query: 388 WFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIF 447
           +   AEL+    R   + V+  ++   + I+   F Y+        +I+   L +L  I 
Sbjct: 447 YVYTAELYPTVVRNMGVGVSSTASRLGS-ILSPYFVYLGAYDRFLPYILMGSLTILTAIL 505

Query: 448 TYFKVPETKGRTFDEIASGFRQGGASQSDKTP 479
           T F +PE+ G    +      +    +  KTP
Sbjct: 506 TLF-LPESFGTPLPDTIDQMLRVKGMKHRKTP 536


>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
           sapiens]
          Length = 546

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 95/383 (24%), Positives = 153/383 (39%), Gaps = 52/383 (13%)

Query: 45  NQTWVHRYGESILPTTLTTLWSL----------SVAIFSVGGMIGSFSVGLFVNRFGRRN 94
           +Q W   Y  S   +T+ T W L          +   F  G ++G+ + G   +RFGRR 
Sbjct: 114 SQGW--EYDHSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRR 171

Query: 95  SMLMMNLLAFVSAVLMGF-SKLGKSFEMLILGRFIIG-VYCGLTTGFVPMYVG--EVSPT 150
            +    L+A+VS +++G  S    S+ M  + R + G    G T   +P+ +   +V   
Sbjct: 172 LL----LVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHR 227

Query: 151 ALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPES 210
            + G L +    G V+ + +      D        W  LL  + +P     + L + PES
Sbjct: 228 TVAGVLSSTFWTGGVMLLALVGYLIRD--------WRWLLLAVTLPCAPGILSLWWVPES 279

Query: 211 PRFLLINRNEENRAKSVLKKLR-GTADVTHDLQEMKEESRQMMREKKV---TILELFRSP 266
            R+LL   + +   + +L   R     V  D    +  S+    E+ V   + L+LFR+P
Sbjct: 280 ARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTP 339

Query: 267 AYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYAT-IGSGIVNTAFTVVSL 325
             R   L  VV+      S      YY  S+ + +G+   VY T +  G V     ++  
Sbjct: 340 RLRHISLCCVVVWFGVNFS------YYGLSL-DVSGLGLNVYQTQLLFGAVELPSKLLVY 392

Query: 326 FVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGP 385
             V  AGRR      L G A     +     LL      S+ +++A+ G  AF E     
Sbjct: 393 LSVRYAGRRLTQAGTLLGTA-----LAFGTRLLVSSDMKSWSTVLAVMG-KAFSEAA--- 443

Query: 386 IPWFIVAELFSQGPRPAAIAVAG 408
              F  A LF+    P  +   G
Sbjct: 444 ---FTTAYLFTSELYPTVLRQTG 463


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 89/408 (21%), Positives = 159/408 (38%), Gaps = 40/408 (9%)

Query: 65  WSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEML 122
           W L +  +  + G + GS  VG F +RFGR+  +L   L+  VS VLM FS    ++  +
Sbjct: 146 WKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSM 202

Query: 123 ILGRFIIGV------YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGL 176
           +L R + G+        G T   +  +VG  S    R  +  ++Q+   VG++      L
Sbjct: 203 LLFRLLQGLVSKGNWMAGYT--LITEFVGSGS----RRTVAIMYQMAFTVGLV-----AL 251

Query: 177 DSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTAD 236
             +      W  L   + +P  L  +     PESPR+LL  +      K +    +    
Sbjct: 252 TGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGK 311

Query: 237 VTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTS 296
           +     +M      +  +   +  +LFR+P  R+   I + L  +      ++V Y    
Sbjct: 312 LPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT------DSVLYQGLI 365

Query: 297 IFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGR-RTLHLIGLAGMAGCAILMTIAL 355
           +   A         + S +V      ++L  ++R GR   + +  L   A C +++ I+ 
Sbjct: 366 LHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFIS- 424

Query: 356 ALLEQLPWMSYLSI-VAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTS 414
                L W++ + + V   G     +     +   + AEL+    R   + V        
Sbjct: 425 ---PDLHWLNIIIMCVGRMGITIAIQ-----MICLVNAELYPTFVRNLGVMVCSSLCDIG 476

Query: 415 NFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDE 462
             I       + ++      I+F VL +L    T   +PETKG    E
Sbjct: 477 GIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLL-LPETKGVALPE 523


>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
          Length = 555

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 87/344 (25%), Positives = 147/344 (42%), Gaps = 57/344 (16%)

Query: 48  WVHRYGESILPTTLTTLWSL----------SVAIFSVGGMIGSFSVGLFVNRFGRRNSML 97
           WV  Y  S+ P+T+   W L          + +++  G ++G+   G   +R G +  ++
Sbjct: 111 WV--YNRSVFPSTIVMEWDLVCEARTLRDLAQSVYMAGVLVGAAVFGSLADRLGCKGPLV 168

Query: 98  MMNL-LAFVSAVLMGFSKLGKSFEMLILGRFIIGV-YCGLTTGFVPMYVGEVSPTALRGA 155
              L LA   A    FS    SF    + RF++G+ + G+    V + V E  PT  R  
Sbjct: 169 WSYLQLAASGAATAYFS----SFSAYCVFRFLMGMTFSGIILNSVSLVV-EWMPTRGRTV 223

Query: 156 LGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLL 215
            G L      +G LI     L  +      W  L   I  P L+  +   + PES R+LL
Sbjct: 224 AGILLGYSFTLGQLI-----LAGVAYLIRPWRCLQFAISAPFLIFFLYSWWLPESSRWLL 278

Query: 216 INRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMRE----------KKVTILELFRS 265
           ++     +++  ++ L+  A +    +E +  ++++M               +IL+LFR+
Sbjct: 279 LH----GKSQLAVQNLQKVAAMNGRKEEGERLTKEVMSSYIQSEFASVCTSNSILDLFRT 334

Query: 266 PAYRQPILIAVVLQLSQQLSGINAVFYYSTSI-FEKAGVQQPVYATIGSGIVNTAFTVVS 324
           PA R+     +V+  S      N+V YY  ++  +K G+   +   +  GI+NT   +V+
Sbjct: 335 PAIRKVTCCLMVIWFS------NSVAYYGLAMDLQKFGLSLYLVQAL-FGIINTPAMLVA 387

Query: 325 LFVVERAGRRT-----LHLIGLAGMA------GCAILMTIALAL 357
              +   GRR      L L GL  +A      G  IL T   AL
Sbjct: 388 TATMIYVGRRATVASFLILAGLMVIANMFVPEGTQILCTAQAAL 431


>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
           sapiens]
          Length = 548

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 92/383 (24%), Positives = 151/383 (39%), Gaps = 50/383 (13%)

Query: 45  NQTWVHRYGESILPTTLTTLWSL----------SVAIFSVGGMIGSFSVGLFVNRFGRRN 94
           +Q W + + E        + W L          +   F  G ++G+ + G   +RFGRR 
Sbjct: 114 SQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRR 173

Query: 95  SMLMMNLLAFVSAVLMGF-SKLGKSFEMLILGRFIIG-VYCGLTTGFVPMYVG--EVSPT 150
            +    L+A+VS +++G  S    S+ M  + R + G    G T   +P+ +   +V   
Sbjct: 174 LL----LVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHR 229

Query: 151 ALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPES 210
            + G L +    G V+ + +      D        W  LL  + +P     + L + PES
Sbjct: 230 TVAGVLSSTFWTGGVMLLALVGYLIRD--------WRWLLLAVTLPCAPGILSLWWVPES 281

Query: 211 PRFLLINRNEENRAKSVLKKLR-GTADVTHDLQEMKEESRQMMREKKV---TILELFRSP 266
            R+LL   + +   + +L   R     V  D    +  S+    E+ V   + L+LFR+P
Sbjct: 282 ARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTP 341

Query: 267 AYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYAT-IGSGIVNTAFTVVSL 325
             R   L  VV+      S      YY  S+ + +G+   VY T +  G V     ++  
Sbjct: 342 RLRHISLCCVVVWFGVNFS------YYGLSL-DVSGLGLNVYQTQLLFGAVELPSKLLVY 394

Query: 326 FVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGP 385
             V  AGRR      L G A     +     LL      S+ +++A+ G  AF E     
Sbjct: 395 LSVRYAGRRLTQAGTLLGTA-----LAFGTRLLVSSDMKSWSTVLAVMG-KAFSEAA--- 445

Query: 386 IPWFIVAELFSQGPRPAAIAVAG 408
              F  A LF+    P  +   G
Sbjct: 446 ---FTTAYLFTSELYPTVLRQTG 465


>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
           sapiens]
          Length = 506

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 69/312 (22%), Positives = 127/312 (40%), Gaps = 33/312 (10%)

Query: 65  WSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEML 122
           W L +  +  + G + GS  VG F +RFGR+  +L   L+  VS VLM FS    ++  +
Sbjct: 146 WKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSM 202

Query: 123 ILGRFIIGV------YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGL 176
           +L R + G+        G T   +  +VG  S    R  +  ++Q+   VG++      L
Sbjct: 203 LLFRLLQGLVSKGNWMAGYT--LITEFVGSGS----RRTVAIMYQMAFTVGLV-----AL 251

Query: 177 DSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTAD 236
             +      W  L   + +P  L  +     PESPR+LL  +      K +    +    
Sbjct: 252 TGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGK 311

Query: 237 VTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTS 296
           +     +M      +  +   +  +LFR+P  R+   I + L  +      ++V Y    
Sbjct: 312 LPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT------DSVLYQGLI 365

Query: 297 IFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGR-RTLHLIGLAGMAGCAILMTIAL 355
           +   A         + S +V      ++L  ++R GR   + +  L   A C +++ I+ 
Sbjct: 366 LHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFIS- 424

Query: 356 ALLEQLPWMSYL 367
                L W++ +
Sbjct: 425 ---PDLHWLNII 433


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 58/237 (24%), Positives = 107/237 (45%), Gaps = 22/237 (9%)

Query: 48  WVHRYGESILPTTLTTL----WSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNL 101
           WV+    S + T    +    W L +  +  +VG  IGS S+G   +RFGR+  +L   L
Sbjct: 126 WVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVL 185

Query: 102 LAFVSAVLMGFSKLGKSFEMLILGRFIIGVY--CGLTTGFVPMYVGEVSPTALRGALGTL 159
           +   + VLM  S    ++  +++ R I G+    G   G++   + E      R  +G  
Sbjct: 186 INAAAGVLMAIS---PTYTWMLIFRLIQGLVSKAGWLIGYI--LITEFVGRRYRRTVGIF 240

Query: 160 HQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRN 219
           +Q+   VG+L+     L  +      W  L   + +P     +     PESPR+ LI++N
Sbjct: 241 YQVAYTVGLLV-----LAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPRW-LISQN 294

Query: 220 EENRAKSVLKKL--RGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILI 274
           +   A  ++K +  +    +   LQ ++ E  +  ++   + L+L R+P  R+  +I
Sbjct: 295 KNAEAMRIIKHIAKKNGKSLPASLQRLRLE-EETGKKLNPSFLDLVRTPQIRKHTMI 350


>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
          Length = 547

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 77/334 (23%), Positives = 139/334 (41%), Gaps = 44/334 (13%)

Query: 66  SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILG 125
           S + + F  G  +G  S G   +RFGR+   L    L  + A+  GFS    S+E   + 
Sbjct: 112 SAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFS---PSYEFFAVT 168

Query: 126 RFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDL 185
           RF++G+  G  +    + + E   TA     G++  L   VG  IAQ   L   + +   
Sbjct: 169 RFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVG--IAQYALLGYFIRS--- 223

Query: 186 WPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVL-------KKLRGTADVT 238
           W  L  ++ +   +  ++  F PESPR+ L ++   + A+  L       +KL+ T  +T
Sbjct: 224 WRTLAILVNLQGTVVFLLSLFIPESPRW-LYSQGRLSEAEEALYLIAKRNRKLKCTFSLT 282

Query: 239 HDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIF 298
           H       E+         + L+LFR   YR  +   ++L     +  + ++ YY  ++ 
Sbjct: 283 HPANRSCRETG--------SFLDLFR---YRVLLGHTLILMF---IWFVCSLVYYGLTL- 327

Query: 299 EKAGVQQPVYATIG-SGIVNTAFTVVSLFVVER---AGRRTLHLIGLAGMAGCAILM--- 351
               +   +YA +  SG++      + ++++ +     +RTL      G   C I+M   
Sbjct: 328 SAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLP 387

Query: 352 ------TIALALLEQLPWMSYLSIVAIFGFVAFF 379
                   A+     L  +  L+I A F  V  +
Sbjct: 388 EKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIY 421


>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
          Length = 542

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 86/384 (22%), Positives = 154/384 (40%), Gaps = 28/384 (7%)

Query: 3   PSSKKLTGRLMLAVG--GAVLGSLQFGY--NTGVINAPQKVIEE-----FYNQTWVHRYG 53
           P     TG  +L +G  G     L+F +  N  + N  Q+ +E       YN T      
Sbjct: 51  PPHNASTGPWVLPMGPNGKPERCLRFVHPPNASLPNDTQRAMEPCLDGWVYNSTKDSIVT 110

Query: 54  ESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFS 113
           E  L      L  ++ +IF  G +IG   +G   +RFGRR  +    LL   S     FS
Sbjct: 111 EWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFS 170

Query: 114 KLGKSFEMLILGRFIIGV-YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQ 172
               +F + ++ RF+ G    G+T   V + V E  PT +R  + T        G  I  
Sbjct: 171 ---PTFPIYMVFRFLCGFGISGITLSTVILNV-EWVPTRMRAIMSTALGYCYTFGQFI-- 224

Query: 173 VFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLR 232
              L  +      W  L   + IP  +  +   + PES R+L+++  + ++A  +L+++ 
Sbjct: 225 ---LPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLS-GKSSKALKILRRVA 280

Query: 233 GTADVTHDLQEMKEESRQMMREKKVTI--LELFRSPAYRQPILIAVVLQLSQQLSGINAV 290
                  + + +  E  ++  +K++++   +   S  +R P+L  +   LS         
Sbjct: 281 VFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFA 340

Query: 291 FYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAIL 350
           +Y      E+ GV   +   I  G V+     +++  +   GR T     L    G  + 
Sbjct: 341 YYSLAMGVEEFGVNLYILQIIFGG-VDVPAKFITILSLSYLGRHTTQAAALLLAGGAILA 399

Query: 351 MTIALALLEQLPWMSYLSIVAIFG 374
           +T        L   +  +++A+FG
Sbjct: 400 LTFV-----PLDLQTVRTVLAVFG 418


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.142    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,175,595
Number of Sequences: 37866
Number of extensions: 721266
Number of successful extensions: 2330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 2217
Number of HSP's gapped (non-prelim): 103
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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