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Search of human proteins with 166197668
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|166197668 CD5 molecule [Homo sapiens]
(495 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|166197668 CD5 molecule [Homo sapiens] 1036 0.0
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 86 8e-17
gi|18152779 scavenger receptor cysteine rich domain containing, ... 86 1e-16
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 85 1e-16
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 85 2e-16
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 81 2e-15
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H... 81 2e-15
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 80 3e-15
gi|44889963 CD163 antigen isoform b [Homo sapiens] 71 3e-12
gi|44662834 CD163 antigen isoform a [Homo sapiens] 71 3e-12
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 62 2e-09
gi|194018748 CD6 molecule [Homo sapiens] 62 2e-09
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] 60 6e-09
gi|5174411 CD5 molecule-like [Homo sapiens] 55 2e-07
gi|4506143 neurotrypsin precursor [Homo sapiens] 49 1e-05
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] 44 3e-04
gi|69354859 ADAM metallopeptidase domain 8 precursor [Homo sapiens] 38 0.024
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo... 37 0.041
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] 35 0.16
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 34 0.27
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] 34 0.35
gi|154426272 hypothetical protein LOC54540 [Homo sapiens] 34 0.35
gi|110431370 espin [Homo sapiens] 33 0.46
gi|22538450 phosphatidylinositol glycan anchor biosynthesis, cla... 33 0.46
gi|22538453 phosphatidylinositol glycan anchor biosynthesis, cla... 33 0.46
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] 33 0.46
gi|5031863 galectin 3 binding protein [Homo sapiens] 33 0.60
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 33 0.60
gi|22212927 nuclear transcription factor, X-box binding 1 isofor... 33 0.78
gi|22212925 nuclear transcription factor, X-box binding 1 isofor... 33 0.78
>gi|166197668 CD5 molecule [Homo sapiens]
Length = 495
Score = 1036 bits (2678), Expect = 0.0
Identities = 495/495 (100%), Positives = 495/495 (100%)
Query: 1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC 60
MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC
Sbjct: 1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC 60
Query: 61 SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS 120
SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS
Sbjct: 61 SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS 120
Query: 121 RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS 180
RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS
Sbjct: 121 RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS 180
Query: 181 LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ 240
LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ
Sbjct: 181 LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ 240
Query: 241 NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL 300
NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL
Sbjct: 241 NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL 300
Query: 301 CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC 360
CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC
Sbjct: 301 CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC 360
Query: 361 KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP 420
KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP
Sbjct: 361 KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP 420
Query: 421 TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPD 480
TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPD
Sbjct: 421 TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPD 480
Query: 481 NSSDSDYDLHGAQRL 495
NSSDSDYDLHGAQRL
Sbjct: 481 NSSDSDYDLHGAQRL 495
>gi|148539844 deleted in malignant brain tumors 1 isoform c
precursor [Homo sapiens]
Length = 2403
Score = 85.9 bits (211), Expect = 8e-17
Identities = 84/309 (27%), Positives = 122/309 (39%), Gaps = 50/309 (16%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D S A+ VC++L CG S
Sbjct: 364 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTSDANVVCRQLGCGWATSAPGN 415
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQKTTP 140
GP ++ + C G +C H+ ++ HS G+ C + T P
Sbjct: 416 ARFGQGSGPIVL-----DDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSD---TLP 467
Query: 141 PTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFL 200
T P T E + RL +GG C G VE GT+ ++ D T D N +
Sbjct: 468 TITLPASTVGSESSLALRL----VNGGDRCQGRVEVLYRGSWGTVCDDSWD-TND-ANVV 521
Query: 201 CNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQ 257
C L CG + G+ P + R W ++ S +C +
Sbjct: 522 CRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS-HNCGHS---E 577
Query: 258 KSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCR 317
+G ++CSG + + RLV G C+G VEV W +CD S + VCR
Sbjct: 578 DAG----VICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA--NVVCR 631
Query: 318 EQQCGSVNS 326
+ CG S
Sbjct: 632 QLGCGWATS 640
Score = 80.5 bits (197), Expect = 3e-15
Identities = 82/333 (24%), Positives = 122/333 (36%), Gaps = 54/333 (16%)
Query: 30 DPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVP 89
D RL + +CQG++E+ + W VC SW D + A+ VC++L CG
Sbjct: 97 DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWA 148
Query: 90 LSL----------GPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLG--------LT 131
+S GP + + C G +C H+ + H+ G +
Sbjct: 149 MSAPGNAWFGQGSGPIAL-----DDVRCSGHESYLWSCPHN-GWLSHNCGHGEDAGVICS 202
Query: 132 CLEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEA 189
+PQ T P + P + P PT + L L +GG C G VE GT+ +
Sbjct: 203 AAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDY 262
Query: 190 QDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNS---- 242
D T D N +C L CG + + G+ P + R W ++
Sbjct: 263 WD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 243 -SCTSLEHC--------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQ 293
+C E R + +G + + RLV G C+G VEV
Sbjct: 321 HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380
Query: 294 GAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326
W +CD S S VCR+ CG S
Sbjct: 381 RGSWGTVCDDSWDTSDA--NVVCRQLGCGWATS 411
Score = 76.6 bits (187), Expect = 5e-14
Identities = 79/321 (24%), Positives = 113/321 (35%), Gaps = 51/321 (15%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL + +CQG++EV + W VC SW D + A+ VC++L CG S
Sbjct: 724 RLVNGSDRCQGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWATSAPGN 775
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q
Sbjct: 776 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 830
Query: 141 PTTRPPPTTTPEPTAP-PRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
P+ PT+ P L L +GG C G VE GT+ ++ D + N
Sbjct: 831 PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSD--ANV 888
Query: 200 LCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSS------------- 243
+C L CG G+ P + R W ++
Sbjct: 889 VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 948
Query: 244 -CTSLEHCFRKIKPQKSGRV-LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALC 301
S H + P + L G + + RLV G C+G VEV W +C
Sbjct: 949 VICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC 1008
Query: 302 DSSSARSSLRWEEVCREQQCG 322
D S + VCR+ CG
Sbjct: 1009 DDSWDTNDA--NVVCRQLGCG 1027
Score = 72.8 bits (177), Expect = 7e-13
Identities = 83/323 (25%), Positives = 119/323 (36%), Gaps = 55/323 (17%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D S A+ VC++L CG S
Sbjct: 853 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTSDANVVCRQLGCGWATSAPGN 904
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQK-TT 139
GP ++ + C G +C H+ ++ HS G+ C +T
Sbjct: 905 ARFGQGSGPIVL-----DDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST 959
Query: 140 PPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDL 196
P P T P T + L L +GG C G VE Y GS GT+ ++ D T D
Sbjct: 960 PSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGS-WGTVCDDSWD-TND- 1016
Query: 197 ENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC--- 250
N +C L CG + G+ P + R W ++ S +C
Sbjct: 1017 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHS 1075
Query: 251 -----------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAA 299
R + +G + + RLV G C+G VEV W
Sbjct: 1076 EDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 1135
Query: 300 LCDSSSARSSLRWEEVCREQQCG 322
+CD + VCR+ CG
Sbjct: 1136 VCDDYWDTNDA--NVVCRQLGCG 1156
Score = 72.4 bits (176), Expect = 9e-13
Identities = 84/323 (26%), Positives = 118/323 (36%), Gaps = 55/323 (17%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC W D + A+ VC++L CG S
Sbjct: 1371 RLVNGGDRCQGRVEVLYRGSWGTVCDDYW--------DTNDANVVCRQLGCGWATSAPGN 1422
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q
Sbjct: 1423 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1477
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLEN 198
P+ PT+ + L L +GG C G VE Y GS GT+ + D T D N
Sbjct: 1478 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGS-WGTVCDDYWD-TND-AN 1534
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC----- 250
+C L CG + + G+ P + R W ++ S +C
Sbjct: 1535 VVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHHED 1593
Query: 251 ----FRKIKPQKSGRV-------LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAA 299
+ Q + R L L G + + RLV G C G VEV W
Sbjct: 1594 AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 1653
Query: 300 LCDSSSARSSLRWEEVCREQQCG 322
+CD S + VCR+ CG
Sbjct: 1654 VCDDSWDTNDA--NVVCRQLGCG 1674
Score = 70.5 bits (171), Expect = 3e-12
Identities = 79/324 (24%), Positives = 118/324 (36%), Gaps = 51/324 (15%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 984 RLVNGGDRCQGRVEVLYQGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 1035
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQKTTP 140
GP ++ + C G +C H+ ++ HS G+ C Q
Sbjct: 1036 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1090
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
P+ PT+ + L L +GG C G VE GT+ + D T D N
Sbjct: 1091 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWD-TND-ANV 1148
Query: 200 LCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC------ 250
+C L CG + G+ P + R W ++ S +C
Sbjct: 1149 VCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHHEDA 1207
Query: 251 -----FRKIKPQKSGRVLA---LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCD 302
+ +P S +G + + RLV G C+G VEV W +CD
Sbjct: 1208 GVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 1267
Query: 303 SSSARSSLRWEEVCREQQCGSVNS 326
+ VCR+ CG S
Sbjct: 1268 DYWDTNDA--NVVCRQLGCGWATS 1289
Score = 69.3 bits (168), Expect = 8e-12
Identities = 82/330 (24%), Positives = 115/330 (34%), Gaps = 61/330 (18%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D + A+ VC++L CG S
Sbjct: 593 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWATSAPGN 644
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQKTTP 140
GP ++ + C G +C + S N H G+ C Q +
Sbjct: 645 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRST 699
Query: 141 P-------TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKT 193
P T PP T E + RL +G C G VE GT+ ++ D T
Sbjct: 700 PRPDTLSTITLPPSTVGSESSLTLRL----VNGSDRCQGRVEVLYRGSWGTVCDDSWD-T 754
Query: 194 QDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC 250
D N +C L CG G+ P + R W ++ S +C
Sbjct: 755 ND-ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNC 812
Query: 251 --------------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQ 296
R + +G + + RLV G C+G VEV
Sbjct: 813 GHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGS 872
Query: 297 WAALCDSSSARSSLRWEEVCREQQCGSVNS 326
W +CD S S VCR+ CG S
Sbjct: 873 WGTVCDDSWDTSDA--NVVCRQLGCGWATS 900
Score = 67.8 bits (164), Expect = 2e-11
Identities = 81/346 (23%), Positives = 114/346 (32%), Gaps = 95/346 (27%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC W D + A+ VC++L CG +S
Sbjct: 1113 RLVNGGDRCQGRVEVLYRGSWGTVCDDYW--------DTNDANVVCRQLGCGWAMSAPGN 1164
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCHS-LGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q
Sbjct: 1165 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1219
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
P+ PT+ + L L +GG C G VE GT+ + D T D N
Sbjct: 1220 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWD-TNDA-NV 1277
Query: 200 LCNNLQCG-----------------------------SFLKHLPET-----EAGRAQDPG 225
+C L CG S+L P G +D G
Sbjct: 1278 VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAG 1337
Query: 226 -----EPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVG 280
+ P P W ++S +G + + RLV
Sbjct: 1338 VICSASQSQPTPSPDTWPTSHAST-----------------------AGSESSLALRLVN 1374
Query: 281 GSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326
G C+G VEV W +CD + VCR+ CG S
Sbjct: 1375 GGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWATS 1418
Score = 58.2 bits (139), Expect = 2e-08
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 39/210 (18%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC W D + A+ VC++L CG +S
Sbjct: 1500 RLVNGGDRCRGRVEVLYQGSWGTVCDDYW--------DTNDANVVCRQLGCGWAMSAPGN 1551
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCHS-LGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q +
Sbjct: 1552 AQFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 1606
Query: 141 P------TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQ 194
P TT P T ++ L L +GG C G VE GT+ ++ D T
Sbjct: 1607 PRPDTWLTTNLPALTVGSESS---LALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWD-TN 1662
Query: 195 DLENFLCNNLQCGSFLKHLPETEAGRAQDP 224
D N +C L CG + G+ P
Sbjct: 1663 D-ANVVCRQLGCGWAMSAPGNARFGQGSGP 1691
Score = 53.1 bits (126), Expect = 6e-07
Identities = 79/334 (23%), Positives = 117/334 (35%), Gaps = 91/334 (27%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 1631 RLVNGGDRCRGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 1682
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQ--KT 138
GP ++ + C G +C H + N H G+ C Q T
Sbjct: 1683 ARFGQGSGPIVL-----DDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1737
Query: 139 TPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLEN 198
T P TTT P++ +C G + FY+ + SY A
Sbjct: 1738 TTDWWHPTTTTTARPSS-------------NCGGFL-FYASGTFSSPSYPA--------- 1774
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDPG----EPREHQPLPIQW----------------- 237
+ NN +C + E +G + G + H +
Sbjct: 1775 YYPNNAKCVWEI----EVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI 1830
Query: 238 -----KIQNSSCTSLEHCFRK-IKPQKSGRVLALLCSGFQPKVQSRLVGGSS---ICEGT 288
+I SS + FR I Q +G + F RLV +S +C G
Sbjct: 1831 CNDTRQIFTSSYNRMTIHFRSDISFQNTG--FLAWYNSFPSDATLRLVNLNSSYGLCAGR 1888
Query: 289 VEVRQGAQWAALCDSSSARSSLRWEEVCREQQCG 322
VE+ G W +CD S E VCR+ CG
Sbjct: 1889 VEIYHGGTWGTVCDDSWTIQEA--EVVCRQLGCG 1920
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 14/74 (18%)
Query: 24 GRLSWYDP---DFQARLTRSNSK---CQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQA 77
G L+WY+ D RL NS C G++E+Y W VC SW +A
Sbjct: 1859 GFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW--------TIQEA 1910
Query: 78 SKVCQRLNCGVPLS 91
VC++L CG +S
Sbjct: 1911 EVVCRQLGCGRAVS 1924
>gi|18152779 scavenger receptor cysteine rich domain containing,
group B (4 domains) [Homo sapiens]
Length = 575
Score = 85.5 bits (210), Expect = 1e-16
Identities = 100/378 (26%), Positives = 140/378 (37%), Gaps = 85/378 (22%)
Query: 8 PLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRS 67
P A +LL + +AS L P + RL S+C+G+LEV W VC W
Sbjct: 33 PQALSFLLLLPLASALQPTPL--PFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDW--- 87
Query: 68 SKQWEDPSQASKVCQRLNCGVPLSL----------GPFLVTYTPQSSIICYGQLGSFSNC 117
D A+ VC++L CG+ L + GP L+ ++ C GQ + S C
Sbjct: 88 -----DVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILL-----DNVECRGQEAALSEC 137
Query: 118 SHSRNDMCHS------LGLTCLEPQKTTPP-----TTRPPPTTTPEPTAPPRLQLVAQSG 166
SR H+ + + C E T PP T+R PPTT P + ++LV G
Sbjct: 138 G-SRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLV--GG 194
Query: 167 GQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQ---- 222
C G VE L GT+ + D +C L CG+ + G
Sbjct: 195 ANLCQGRVEILHSGLWGTVCDD--DWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHIL 252
Query: 223 ------DPGEPREHQPLPIQWKIQN-----------------------SSCTSLEHCFRK 253
+ GEPR + W + N SS T + ++
Sbjct: 253 LDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQT 312
Query: 254 ------IKPQKSGRVLALLCSGFQPKVQS---RLVGGSSICEGTVEVRQGAQWAALCDSS 304
+ PQ S L + + +S RLVGG C G VEV W +CD
Sbjct: 313 DPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDD 372
Query: 305 SARSSLRWEEVCREQQCG 322
+ R CRE CG
Sbjct: 373 WDFADAR--VACREAGCG 388
Score = 64.3 bits (155), Expect = 2e-10
Identities = 59/202 (29%), Positives = 78/202 (38%), Gaps = 25/202 (12%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPL---SL 92
RL C+G++EV GW VC W D + A C+ CG L L
Sbjct: 345 RLVGGPGPCRGRVEVLHAGGWGTVCDDDW--------DFADARVACREAGCGPALGATGL 396
Query: 93 GPFLVTYTP--QSSIICYGQLGSFSNCSH---SRNDMCH--SLGLTCLEPQKTTPPTTRP 145
G F P ++ C G S+C H +++ H G C P++ +
Sbjct: 397 GHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQD 456
Query: 146 PPTTTPEPTAPPR---LQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCN 202
TT PT PR L+LV +G C G VE Y G GT+ +A D LC
Sbjct: 457 GSETTRVPTPRPRDGHLRLV--NGAHRCEGRVELYLGQRWGTVCDDAWDLR--AAGVLCR 512
Query: 203 NLQCGSFLKHLPETEAGRAQDP 224
L CG L E G + P
Sbjct: 513 QLGCGQALAAPGEAHFGPGRGP 534
Score = 45.8 bits (107), Expect = 9e-05
Identities = 79/349 (22%), Positives = 116/349 (33%), Gaps = 83/349 (23%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGP- 94
RL + CQG++E+ W VC WG A+ VC++L CG ++
Sbjct: 190 RLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD--------AAVVCRQLGCGAAMAATTN 241
Query: 95 ----FLVTYTPQSSIICYG---------QLG-SFSNCSHSRND--MCHSLG---LTCLEP 135
+ + ++ C G LG NC H + +C LG LT L
Sbjct: 242 AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPS 301
Query: 136 QKTTPPTT-RPPPTTT---PEPTAPP---------------RLQLVAQSGGQHCAGVVEF 176
T + P+ T P+P+ RL+LV G C G VE
Sbjct: 302 SATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGP--CRGRVEV 359
Query: 177 YSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP----------GE 226
GT+ + D C CG L G + P E
Sbjct: 360 LHAGGWGTVCDDDWDFAD--ARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
Query: 227 PREHQPLPIQWKIQNSS--------CTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRL 278
R + W N C E ++ Q+ G + + RL
Sbjct: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQV--QQDGSETTRVPTPRPRDGHLRL 475
Query: 279 VGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWE-----EVCREQQCG 322
V G+ CEG VE+ G +W +CD + W+ +CR+ CG
Sbjct: 476 VNGAHRCEGRVELYLGQRWGTVCDDA-------WDLRAAGVLCRQLGCG 517
Score = 45.8 bits (107), Expect = 9e-05
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 23/102 (22%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
D RL +C+G++E+YL W VC +W D A +C++L CG L+
Sbjct: 470 DGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAW--------DLRAAGVLCRQLGCGQALA 521
Query: 92 L----------GPFLVTYTPQSSIICYGQLGSFSNCSHSRND 123
GP L+ ++ C G+ + CSH R D
Sbjct: 522 APGEAHFGPGRGPILL-----DNVKCRGEESALLLCSHIRWD 558
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/208 (22%), Positives = 70/208 (33%), Gaps = 46/208 (22%)
Query: 146 PPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQ 205
P + +PT P +L G C G +E G G++ + D N +C L
Sbjct: 43 PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVD--ANVVCRQLG 100
Query: 206 CGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSG----- 260
CG L G+ + P + N C E + + G
Sbjct: 101 CGLALPVPRPLAFGQGRGP------------ILLDNVECRGQEAALSECGSRGWGVHNCF 148
Query: 261 --RVLALLCSGFQP-----------------------KVQSRLVGGSSICEGTVEVRQGA 295
+A+LC F P + RLVGG+++C+G VE+
Sbjct: 149 HYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSG 208
Query: 296 QWAALCDSSSARSSLRWEEVCREQQCGS 323
W +CD VCR+ CG+
Sbjct: 209 LWGTVCDDDWGLPDA--AVVCRQLGCGA 234
>gi|148539842 deleted in malignant brain tumors 1 isoform b
precursor [Homo sapiens]
Length = 2413
Score = 85.1 bits (209), Expect = 1e-16
Identities = 84/312 (26%), Positives = 122/312 (39%), Gaps = 46/312 (14%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D S A+ VC++L CG S
Sbjct: 364 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTSDANVVCRQLGCGWATSAPGN 415
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQK-TT 139
GP ++ + C G +C H+ ++ HS G+ C +T
Sbjct: 416 ARFGQGSGPIVL-----DDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST 470
Query: 140 PPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLE 197
P P T P T + L L +GG C G VE GT+ ++ D T D
Sbjct: 471 PSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWD-TND-A 528
Query: 198 NFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHCFRKI 254
N +C L CG + G+ P + R W ++ S +C
Sbjct: 529 NVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS-HNCGHS- 586
Query: 255 KPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEE 314
+ +G ++CSG + + RLV G C+G VEV W +CD S +
Sbjct: 587 --EDAG----VICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA--NV 638
Query: 315 VCREQQCGSVNS 326
VCR+ CG S
Sbjct: 639 VCRQLGCGWATS 650
Score = 80.5 bits (197), Expect = 3e-15
Identities = 82/333 (24%), Positives = 122/333 (36%), Gaps = 54/333 (16%)
Query: 30 DPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVP 89
D RL + +CQG++E+ + W VC SW D + A+ VC++L CG
Sbjct: 97 DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWA 148
Query: 90 LSL----------GPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLG--------LT 131
+S GP + + C G +C H+ + H+ G +
Sbjct: 149 MSAPGNAWFGQGSGPIAL-----DDVRCSGHESYLWSCPHN-GWLSHNCGHGEDAGVICS 202
Query: 132 CLEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEA 189
+PQ T P + P + P PT + L L +GG C G VE GT+ +
Sbjct: 203 AAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDY 262
Query: 190 QDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNS---- 242
D T D N +C L CG + + G+ P + R W ++
Sbjct: 263 WD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 243 -SCTSLEHC--------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQ 293
+C E R + +G + + RLV G C+G VEV
Sbjct: 321 HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380
Query: 294 GAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326
W +CD S S VCR+ CG S
Sbjct: 381 RGSWGTVCDDSWDTSDA--NVVCRQLGCGWATS 411
Score = 76.6 bits (187), Expect = 5e-14
Identities = 79/321 (24%), Positives = 113/321 (35%), Gaps = 51/321 (15%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL + +CQG++EV + W VC SW D + A+ VC++L CG S
Sbjct: 734 RLVNGSDRCQGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWATSAPGN 785
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q
Sbjct: 786 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840
Query: 141 PTTRPPPTTTPEPTAP-PRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
P+ PT+ P L L +GG C G VE GT+ ++ D + N
Sbjct: 841 PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSD--ANV 898
Query: 200 LCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSS------------- 243
+C L CG G+ P + R W ++
Sbjct: 899 VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 958
Query: 244 -CTSLEHCFRKIKPQKSGRV-LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALC 301
S H + P + L G + + RLV G C+G VEV W +C
Sbjct: 959 VICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC 1018
Query: 302 DSSSARSSLRWEEVCREQQCG 322
D S + VCR+ CG
Sbjct: 1019 DDSWDTNDA--NVVCRQLGCG 1037
Score = 72.8 bits (177), Expect = 7e-13
Identities = 83/323 (25%), Positives = 119/323 (36%), Gaps = 55/323 (17%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D S A+ VC++L CG S
Sbjct: 863 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTSDANVVCRQLGCGWATSAPGN 914
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQK-TT 139
GP ++ + C G +C H+ ++ HS G+ C +T
Sbjct: 915 ARFGQGSGPIVL-----DDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST 969
Query: 140 PPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDL 196
P P T P T + L L +GG C G VE Y GS GT+ ++ D T D
Sbjct: 970 PSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGS-WGTVCDDSWD-TND- 1026
Query: 197 ENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC--- 250
N +C L CG + G+ P + R W ++ S +C
Sbjct: 1027 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHS 1085
Query: 251 -----------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAA 299
R + +G + + RLV G C+G VEV W
Sbjct: 1086 EDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 1145
Query: 300 LCDSSSARSSLRWEEVCREQQCG 322
+CD + VCR+ CG
Sbjct: 1146 VCDDYWDTNDA--NVVCRQLGCG 1166
Score = 72.4 bits (176), Expect = 9e-13
Identities = 84/323 (26%), Positives = 118/323 (36%), Gaps = 55/323 (17%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC W D + A+ VC++L CG S
Sbjct: 1381 RLVNGGDRCQGRVEVLYRGSWGTVCDDYW--------DTNDANVVCRQLGCGWATSAPGN 1432
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q
Sbjct: 1433 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1487
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLEN 198
P+ PT+ + L L +GG C G VE Y GS GT+ + D T D N
Sbjct: 1488 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGS-WGTVCDDYWD-TND-AN 1544
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC----- 250
+C L CG + + G+ P + R W ++ S +C
Sbjct: 1545 VVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHHED 1603
Query: 251 ----FRKIKPQKSGRV-------LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAA 299
+ Q + R L L G + + RLV G C G VEV W
Sbjct: 1604 AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 1663
Query: 300 LCDSSSARSSLRWEEVCREQQCG 322
+CD S + VCR+ CG
Sbjct: 1664 VCDDSWDTNDA--NVVCRQLGCG 1684
Score = 70.5 bits (171), Expect = 3e-12
Identities = 79/324 (24%), Positives = 118/324 (36%), Gaps = 51/324 (15%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 994 RLVNGGDRCQGRVEVLYQGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 1045
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQKTTP 140
GP ++ + C G +C H+ ++ HS G+ C Q
Sbjct: 1046 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
P+ PT+ + L L +GG C G VE GT+ + D T D N
Sbjct: 1101 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWD-TND-ANV 1158
Query: 200 LCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC------ 250
+C L CG + G+ P + R W ++ S +C
Sbjct: 1159 VCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHHEDA 1217
Query: 251 -----FRKIKPQKSGRVLA---LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCD 302
+ +P S +G + + RLV G C+G VEV W +CD
Sbjct: 1218 GVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 1277
Query: 303 SSSARSSLRWEEVCREQQCGSVNS 326
+ VCR+ CG S
Sbjct: 1278 DYWDTNDA--NVVCRQLGCGWATS 1299
Score = 69.3 bits (168), Expect = 8e-12
Identities = 82/330 (24%), Positives = 115/330 (34%), Gaps = 61/330 (18%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D + A+ VC++L CG S
Sbjct: 603 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWATSAPGN 654
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQKTTP 140
GP ++ + C G +C + S N H G+ C Q +
Sbjct: 655 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRST 709
Query: 141 P-------TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKT 193
P T PP T E + RL +G C G VE GT+ ++ D T
Sbjct: 710 PRPDTLSTITLPPSTVGSESSLTLRL----VNGSDRCQGRVEVLYRGSWGTVCDDSWD-T 764
Query: 194 QDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC 250
D N +C L CG G+ P + R W ++ S +C
Sbjct: 765 ND-ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNC 822
Query: 251 --------------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQ 296
R + +G + + RLV G C+G VEV
Sbjct: 823 GHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGS 882
Query: 297 WAALCDSSSARSSLRWEEVCREQQCGSVNS 326
W +CD S S VCR+ CG S
Sbjct: 883 WGTVCDDSWDTSDA--NVVCRQLGCGWATS 910
Score = 67.8 bits (164), Expect = 2e-11
Identities = 81/346 (23%), Positives = 114/346 (32%), Gaps = 95/346 (27%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC W D + A+ VC++L CG +S
Sbjct: 1123 RLVNGGDRCQGRVEVLYRGSWGTVCDDYW--------DTNDANVVCRQLGCGWAMSAPGN 1174
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCHS-LGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q
Sbjct: 1175 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1229
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
P+ PT+ + L L +GG C G VE GT+ + D T D N
Sbjct: 1230 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWD-TNDA-NV 1287
Query: 200 LCNNLQCG-----------------------------SFLKHLPET-----EAGRAQDPG 225
+C L CG S+L P G +D G
Sbjct: 1288 VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAG 1347
Query: 226 -----EPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVG 280
+ P P W ++S +G + + RLV
Sbjct: 1348 VICSASQSQPTPSPDTWPTSHAST-----------------------AGSESSLALRLVN 1384
Query: 281 GSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326
G C+G VEV W +CD + VCR+ CG S
Sbjct: 1385 GGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWATS 1428
Score = 58.2 bits (139), Expect = 2e-08
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 39/210 (18%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC W D + A+ VC++L CG +S
Sbjct: 1510 RLVNGGDRCRGRVEVLYQGSWGTVCDDYW--------DTNDANVVCRQLGCGWAMSAPGN 1561
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCHS-LGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q +
Sbjct: 1562 AQFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 1616
Query: 141 P------TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQ 194
P TT P T ++ L L +GG C G VE GT+ ++ D T
Sbjct: 1617 PRPDTWLTTNLPALTVGSESS---LALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWD-TN 1672
Query: 195 DLENFLCNNLQCGSFLKHLPETEAGRAQDP 224
D N +C L CG + G+ P
Sbjct: 1673 D-ANVVCRQLGCGWAMSAPGNARFGQGSGP 1701
Score = 53.1 bits (126), Expect = 6e-07
Identities = 79/334 (23%), Positives = 117/334 (35%), Gaps = 91/334 (27%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 1641 RLVNGGDRCRGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 1692
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQ--KT 138
GP ++ + C G +C H + N H G+ C Q T
Sbjct: 1693 ARFGQGSGPIVL-----DDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1747
Query: 139 TPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLEN 198
T P TTT P++ +C G + FY+ + SY A
Sbjct: 1748 TTDWWHPTTTTTARPSS-------------NCGGFL-FYASGTFSSPSYPA--------- 1784
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDPG----EPREHQPLPIQW----------------- 237
+ NN +C + E +G + G + H +
Sbjct: 1785 YYPNNAKCVWEI----EVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI 1840
Query: 238 -----KIQNSSCTSLEHCFRK-IKPQKSGRVLALLCSGFQPKVQSRLVGGSS---ICEGT 288
+I SS + FR I Q +G + F RLV +S +C G
Sbjct: 1841 CNDTRQIFTSSYNRMTIHFRSDISFQNTG--FLAWYNSFPSDATLRLVNLNSSYGLCAGR 1898
Query: 289 VEVRQGAQWAALCDSSSARSSLRWEEVCREQQCG 322
VE+ G W +CD S E VCR+ CG
Sbjct: 1899 VEIYHGGTWGTVCDDSWTIQEA--EVVCRQLGCG 1930
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 14/74 (18%)
Query: 24 GRLSWYDP---DFQARLTRSNSK---CQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQA 77
G L+WY+ D RL NS C G++E+Y W VC SW +A
Sbjct: 1869 GFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW--------TIQEA 1920
Query: 78 SKVCQRLNCGVPLS 91
VC++L CG +S
Sbjct: 1921 EVVCRQLGCGRAVS 1934
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 84.7 bits (208), Expect = 2e-16
Identities = 88/328 (26%), Positives = 123/328 (37%), Gaps = 54/328 (16%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D S A+ VC++L CG S
Sbjct: 364 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTSDANVVCRQLGCGWATSAPGN 415
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQK-TT 139
GP ++ + C G +C H+ ++ HS G+ C +T
Sbjct: 416 ARFGQGSGPIVL-----DDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST 470
Query: 140 PPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLE 197
P P T P T + L L +GG C G VE GT+ ++ D T D
Sbjct: 471 PSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWD-TND-A 528
Query: 198 NFLCNNLQCGSFLKHLPETEAGRAQDP---------GEPREHQPLPIQ-WKIQNSS---- 243
N +C L CG + G+ P G P W N
Sbjct: 529 NVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED 588
Query: 244 ----CTSLEHCFRKIKPQKSGRVLAL-LCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWA 298
C++L+ I+P+ AL C G + + RLV G C+G VEV W
Sbjct: 589 AGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWG 648
Query: 299 ALCDSSSARSSLRWEEVCREQQCGSVNS 326
+CD S + VCR+ CG S
Sbjct: 649 TVCDDSWDTNDA--NVVCRQLGCGWATS 674
Score = 81.3 bits (199), Expect = 2e-15
Identities = 82/333 (24%), Positives = 122/333 (36%), Gaps = 54/333 (16%)
Query: 30 DPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVP 89
D RL + +CQG++E+ + W VC SW D + A+ VC++L CG
Sbjct: 97 DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWA 148
Query: 90 LSL----------GPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLG--------LT 131
+S GP + + C G +C H+ + H+ G +
Sbjct: 149 MSAPGNAWFGQGSGPIAL-----DDVRCSGHESYLWSCPHN-GWLSHNCGHGEDAGVICS 202
Query: 132 CLEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEA 189
+PQ T P + P + P PT + L L +GG C G VE GT+ +
Sbjct: 203 AAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDY 262
Query: 190 QDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNS---- 242
D T D N +C L CG + + G+ P + R W ++
Sbjct: 263 WD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 243 -SCTSLEHC--------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQ 293
+C E R + +G + + RLV G C+G VEV
Sbjct: 321 HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY 380
Query: 294 GAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326
W +CD S S VCR+ CG S
Sbjct: 381 RGSWGTVCDDSWDTSDA--NVVCRQLGCGWATS 411
Score = 75.9 bits (185), Expect = 8e-14
Identities = 84/323 (26%), Positives = 122/323 (37%), Gaps = 55/323 (17%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 756 RLVNGGDRCQGRVEVLYQGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 807
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQKTTP 140
GP ++ + C G +C H+ ++ HS G+ C Q
Sbjct: 808 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 862
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLEN 198
P+ PT+ + L L +GG C G VE Y GS GT+ + D T D N
Sbjct: 863 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGS-WGTVCDDYWD-TND-AN 919
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC----- 250
+C L CG + + G+ P + R W ++ S +C
Sbjct: 920 VVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHHED 978
Query: 251 ----FRKIKPQKSGRV-------LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAA 299
+ Q + R L L G + + RLV G C G VEV W
Sbjct: 979 AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 1038
Query: 300 LCDSSSARSSLRWEEVCREQQCG 322
+CD S + VCR+ CG
Sbjct: 1039 VCDDSWDTNDA--NVVCRQLGCG 1059
Score = 67.8 bits (164), Expect = 2e-11
Identities = 80/321 (24%), Positives = 116/321 (36%), Gaps = 53/321 (16%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D + A+ VC++L CG S
Sbjct: 627 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWATSAPGN 678
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQ-KTT 139
GP ++ + C G +C + S N H G+ C Q ++T
Sbjct: 679 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRST 733
Query: 140 PPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLEN 198
P P + + L L +GG C G VE Y GS GT+ ++ D T D N
Sbjct: 734 PRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGS-WGTVCDDSWD-TND-AN 790
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC----- 250
+C L CG + G+ P + R W ++ S +C
Sbjct: 791 VVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHSED 849
Query: 251 ---------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALC 301
R + +G + + RLV G C G VEV W +C
Sbjct: 850 AGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVC 909
Query: 302 DSSSARSSLRWEEVCREQQCG 322
D + VCR+ CG
Sbjct: 910 DDYWDTNDA--NVVCRQLGCG 928
Score = 58.2 bits (139), Expect = 2e-08
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 39/210 (18%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC W D + A+ VC++L CG +S
Sbjct: 885 RLVNGGDRCRGRVEVLYQGSWGTVCDDYW--------DTNDANVVCRQLGCGWAMSAPGN 936
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q +
Sbjct: 937 AQFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 991
Query: 141 P------TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQ 194
P TT P T ++ L L +GG C G VE GT+ ++ D T
Sbjct: 992 PRPDTWLTTNLPALTVGSESS---LALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWD-TN 1047
Query: 195 DLENFLCNNLQCGSFLKHLPETEAGRAQDP 224
D N +C L CG + G+ P
Sbjct: 1048 D-ANVVCRQLGCGWAMSAPGNARFGQGSGP 1076
Score = 53.1 bits (126), Expect = 6e-07
Identities = 79/334 (23%), Positives = 117/334 (35%), Gaps = 91/334 (27%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 1016 RLVNGGDRCRGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 1067
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQ--KT 138
GP ++ + C G +C H + N H G+ C Q T
Sbjct: 1068 ARFGQGSGPIVL-----DDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1122
Query: 139 TPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLEN 198
T P TTT P++ +C G + FY+ + SY A
Sbjct: 1123 TTDWWHPTTTTTARPSS-------------NCGGFL-FYASGTFSSPSYPA--------- 1159
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDPG----EPREHQPLPIQW----------------- 237
+ NN +C + E +G + G + H +
Sbjct: 1160 YYPNNAKCVWEI----EVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI 1215
Query: 238 -----KIQNSSCTSLEHCFRK-IKPQKSGRVLALLCSGFQPKVQSRLVGGSS---ICEGT 288
+I SS + FR I Q +G + F RLV +S +C G
Sbjct: 1216 CNDTRQIFTSSYNRMTIHFRSDISFQNTG--FLAWYNSFPSDATLRLVNLNSSYGLCAGR 1273
Query: 289 VEVRQGAQWAALCDSSSARSSLRWEEVCREQQCG 322
VE+ G W +CD S E VCR+ CG
Sbjct: 1274 VEIYHGGTWGTVCDDSWTIQEA--EVVCRQLGCG 1305
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 14/74 (18%)
Query: 24 GRLSWYDP---DFQARLTRSNSK---CQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQA 77
G L+WY+ D RL NS C G++E+Y W VC SW +A
Sbjct: 1244 GFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW--------TIQEA 1295
Query: 78 SKVCQRLNCGVPLS 91
VC++L CG +S
Sbjct: 1296 EVVCRQLGCGRAVS 1309
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 81.3 bits (199), Expect = 2e-15
Identities = 82/333 (24%), Positives = 122/333 (36%), Gaps = 54/333 (16%)
Query: 30 DPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVP 89
D RL + +CQG++E+ + W VC SW D + A+ VC++L CG
Sbjct: 97 DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWA 148
Query: 90 LSL----------GPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLG--------LT 131
+S GP + + C G +C H+ + H+ G +
Sbjct: 149 MSAPGNAWFGQGSGPIAL-----DDVRCSGHESYLWSCPHN-GWLSHNCGHGEDAGVICS 202
Query: 132 CLEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEA 189
+PQ T P + P + P PT + L L +GG C G VE GT+ +
Sbjct: 203 AAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDY 262
Query: 190 QDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNS---- 242
D T D N +C L CG + + G+ P + R W ++
Sbjct: 263 WD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 243 -SCTSLEHC--------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQ 293
+C E R + +G + + RLV G C+G VEV
Sbjct: 321 HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY 380
Query: 294 GAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326
W +CD S S VCR+ CG S
Sbjct: 381 RGSWGTVCDDSWDTSDA--NVVCRQLGCGWATS 411
Score = 75.9 bits (185), Expect = 8e-14
Identities = 84/323 (26%), Positives = 122/323 (37%), Gaps = 55/323 (17%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 630 RLVNGGDRCQGRVEVLYQGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 681
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQKTTP 140
GP ++ + C G +C H+ ++ HS G+ C Q
Sbjct: 682 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 736
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLEN 198
P+ PT+ + L L +GG C G VE Y GS GT+ + D T D N
Sbjct: 737 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGS-WGTVCDDYWD-TND-AN 793
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC----- 250
+C L CG + + G+ P + R W ++ S +C
Sbjct: 794 VVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHHED 852
Query: 251 ----FRKIKPQKSGRV-------LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAA 299
+ Q + R L L G + + RLV G C G VEV W
Sbjct: 853 AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 912
Query: 300 LCDSSSARSSLRWEEVCREQQCG 322
+CD S + VCR+ CG
Sbjct: 913 VCDDSWDTNDA--NVVCRQLGCG 933
Score = 72.0 bits (175), Expect = 1e-12
Identities = 83/329 (25%), Positives = 116/329 (35%), Gaps = 61/329 (18%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D S A+ VC++L CG S
Sbjct: 364 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTSDANVVCRQLGCGWATSAPGN 415
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTC--LEPQKT 138
GP ++ + C G +C H+ ++ HS G+ C T
Sbjct: 416 ARFGQGSGPIVL-----DDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST 470
Query: 139 TPPTTRPPPTTTPEPTAP-------PRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQD 191
P R T P T P L L +GG C G VE GT+ ++ D
Sbjct: 471 PSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWD 530
Query: 192 KTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---------GEPREHQPLPIQ-WKIQN 241
T D N +C L CG + G+ P G P W N
Sbjct: 531 -TND-ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN 588
Query: 242 SS--------CTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQ 293
C++ + R + +G + + RLV G C+G VEV
Sbjct: 589 CGHSEDAGVICSAAQS--RSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY 646
Query: 294 GAQWAALCDSSSARSSLRWEEVCREQQCG 322
W +CD S + VCR+ CG
Sbjct: 647 QGSWGTVCDDSWDTNDA--NVVCRQLGCG 673
Score = 70.9 bits (172), Expect = 3e-12
Identities = 81/317 (25%), Positives = 117/317 (36%), Gaps = 45/317 (14%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPF 95
RL +CQG++EV + W VC SW D + A+ VC++L CG + L P
Sbjct: 501 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWAM-LAPG 551
Query: 96 LVTYTPQSSII------CYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQKTTPPTTR 144
+ S I C G +C H+ ++ HS G+ C Q + P
Sbjct: 552 NARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPD 611
Query: 145 PPPTTTPEPT-APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCN 202
PT+ + L L +GG C G VE Y GS GT+ ++ D T D N +C
Sbjct: 612 TWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGS-WGTVCDDSWD-TND-ANVVCR 668
Query: 203 NLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC--------- 250
L CG + G+ P + R W ++ S +C
Sbjct: 669 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHSEDAGVI 727
Query: 251 -----FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSS 305
R + +G + + RLV G C G VEV W +CD
Sbjct: 728 CSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYW 787
Query: 306 ARSSLRWEEVCREQQCG 322
+ VCR+ CG
Sbjct: 788 DTNDA--NVVCRQLGCG 802
Score = 58.2 bits (139), Expect = 2e-08
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 39/210 (18%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC W D + A+ VC++L CG +S
Sbjct: 759 RLVNGGDRCRGRVEVLYQGSWGTVCDDYW--------DTNDANVVCRQLGCGWAMSAPGN 810
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCHS-LGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q +
Sbjct: 811 AQFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 865
Query: 141 P------TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQ 194
P TT P T ++ L L +GG C G VE GT+ ++ D T
Sbjct: 866 PRPDTWLTTNLPALTVGSESS---LALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWD-TN 921
Query: 195 DLENFLCNNLQCGSFLKHLPETEAGRAQDP 224
D N +C L CG + G+ P
Sbjct: 922 D-ANVVCRQLGCGWAMSAPGNARFGQGSGP 950
Score = 53.1 bits (126), Expect = 6e-07
Identities = 79/334 (23%), Positives = 117/334 (35%), Gaps = 91/334 (27%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 890 RLVNGGDRCRGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 941
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQ--KT 138
GP ++ + C G +C H + N H G+ C Q T
Sbjct: 942 ARFGQGSGPIVL-----DDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 996
Query: 139 TPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLEN 198
T P TTT P++ +C G + FY+ + SY A
Sbjct: 997 TTDWWHPTTTTTARPSS-------------NCGGFL-FYASGTFSSPSYPA--------- 1033
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDPG----EPREHQPLPIQW----------------- 237
+ NN +C + E +G + G + H +
Sbjct: 1034 YYPNNAKCVWEI----EVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI 1089
Query: 238 -----KIQNSSCTSLEHCFRK-IKPQKSGRVLALLCSGFQPKVQSRLVGGSS---ICEGT 288
+I SS + FR I Q +G + F RLV +S +C G
Sbjct: 1090 CNDTRQIFTSSYNRMTIHFRSDISFQNTG--FLAWYNSFPSDATLRLVNLNSSYGLCAGR 1147
Query: 289 VEVRQGAQWAALCDSSSARSSLRWEEVCREQQCG 322
VE+ G W +CD S E VCR+ CG
Sbjct: 1148 VEIYHGGTWGTVCDDSWTIQEA--EVVCRQLGCG 1179
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 14/74 (18%)
Query: 24 GRLSWYDP---DFQARLTRSNSK---CQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQA 77
G L+WY+ D RL NS C G++E+Y W VC SW +A
Sbjct: 1118 GFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW--------TIQEA 1169
Query: 78 SKVCQRLNCGVPLS 91
VC++L CG +S
Sbjct: 1170 EVVCRQLGCGRAVS 1183
>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
sapiens]
Length = 1453
Score = 81.3 bits (199), Expect = 2e-15
Identities = 84/339 (24%), Positives = 128/339 (37%), Gaps = 73/339 (21%)
Query: 18 LVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQA 77
++ +C G +W RL +++C G+LEVY + W VC W + A
Sbjct: 571 VIVTCSGDATW-----GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKA--------A 617
Query: 78 SKVCQRLNCG---VPLSLGPFLVTYTP--QSSIICYGQLGSFSNCSHS---RNDMCHS-- 127
+ VC +L+C + + LG Y + C G +C +S ND HS
Sbjct: 618 AVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSED 677
Query: 128 LGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISY 187
+G+ C + ++L G CAG VE G +
Sbjct: 678 VGVICSDASD---------------------MELRLVGGSSRCAGKVEVNVQGAVGILC- 715
Query: 188 EAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCT-- 245
A ++ +C L+CGS ++ E + + NS CT
Sbjct: 716 -ANGWGMNIAEVVCRQLECGSAIRVSREP------------HFTERTLHILMSNSGCTGG 762
Query: 246 --SLEHCFRKIKPQKSGRV---LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL 300
SL C R Q + + +L+CS + Q RLVG C G VEV+ W ++
Sbjct: 763 EASLWDCIRWEWKQTACHLNMEASLICSAHR---QPRLVGADMPCSGRVEVKHADTWRSV 819
Query: 301 CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRG 339
CDS + + +CRE CG S L GD +G
Sbjct: 820 CDSDFSLHAA--NVLCRELNCGDAIS---LSVGDHFGKG 853
Score = 65.9 bits (159), Expect = 8e-11
Identities = 90/381 (23%), Positives = 142/381 (37%), Gaps = 85/381 (22%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPF 95
RL N+ C G++EV ++ W +C W ++ A+ VC++L C P S
Sbjct: 156 RLVDGNNSCSGRVEVKFQERWGTICDDGWNLNT--------AAVVCRQLGC--PSSFISS 205
Query: 96 LVTYTPQ-------SSIICYGQLGSFSNCSH---SRNDMCHS--LGLTCLEPQKTTPPTT 143
V +P I+C G + NC H +D H+ + LTC +
Sbjct: 206 GVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSD------ 259
Query: 144 RPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNN 203
L+L G C G VE GT+ + + + +C
Sbjct: 260 ---------------LELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAA--ADVVCKQ 302
Query: 204 LQCGSFLKH--LPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGR 261
L CG+ L LP ++G + W + SC+ E + SG
Sbjct: 303 LGCGTALHFAGLPHLQSGS-------------DVVW-LDGVSCSGNESFLWDCR--HSGT 346
Query: 262 V---------LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRW 312
V ++++CS ++ RL GS+ C G VEVR QW +CD +
Sbjct: 347 VNFDCLHQNDVSVICSD-GADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQAL- 404
Query: 313 EEVCREQQC-----GSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTC 367
VC++ C GS + +A D + C + + LW+ +Y K TC
Sbjct: 405 -VVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESA----LWD-CTYDGKAKRTC 458
Query: 368 QDPNPAGLAAGTVASIILALV 388
+ AG+ A + L LV
Sbjct: 459 FRRSDAGVICSDKADLDLRLV 479
Score = 65.9 bits (159), Expect = 8e-11
Identities = 78/308 (25%), Positives = 120/308 (38%), Gaps = 61/308 (19%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
D RL ++S C G+LEV + W VC W + A+ VC++L CG P+
Sbjct: 473 DLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRN--------AAVVCKQLGCGKPMH 524
Query: 92 LGPFLVTYTPQSS-------IICYGQLGSFSNCSHS---RNDMCHSLGLTCLEPQKTTPP 141
+ F +TY ++S + C G + +C HS +++ H
Sbjct: 525 V--FGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVH--------------- 567
Query: 142 TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLC 201
R T A L+LV G C+G +E Y GT+ + + +C
Sbjct: 568 --REDVIVTCSGDATWGLRLV--GGSNRCSGRLEVYFQGRWGTVCDDGWN--SKAAAVVC 621
Query: 202 NNLQCGSFLKHL----PETEAGR--AQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIK 255
+ L C S + + T G+ D + L W +NS + C
Sbjct: 622 SQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDL---WSCRNSGWGN-NDC----- 672
Query: 256 PQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEV 315
+ ++CS ++ RLVGGSS C G VEV LC + + E V
Sbjct: 673 --SHSEDVGVICSD-ASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIA--EVV 727
Query: 316 CREQQCGS 323
CR+ +CGS
Sbjct: 728 CRQLECGS 735
Score = 63.2 bits (152), Expect = 5e-10
Identities = 78/314 (24%), Positives = 120/314 (38%), Gaps = 77/314 (24%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
D + RL +S+C G++E+Y W +C W D S A VCQ+L CGV +
Sbjct: 1033 DKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGW--------DLSDAHVVCQKLGCGVAFN 1084
Query: 92 L----------GPFLVTYTPQSSIICYGQLGSFSNC---SHSRNDMCH--SLGLTCLEPQ 136
GP + + C G C ++D H G+ C
Sbjct: 1085 ATVSAHFGEGSGPIWL-----DDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC---- 1135
Query: 137 KTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQD 195
E TA L+L +++ + CAG +E FY+G+ G S ++ T
Sbjct: 1136 --------------SEFTA---LRLYSETETESCAGRLEVFYNGTWG---SVGRRNITTA 1175
Query: 196 LENFLCNNLQCGS----FLKHLPETEAG--RAQDPGEPREHQPLPIQWKIQNSSCTSLEH 249
+ +C L CG L L +T +G D P+ H + W+ C S
Sbjct: 1176 IAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISI---WQ-----CLSAPW 1227
Query: 250 CFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSS 309
R P + + + + R+ GG + C G VE+ W +CD S +
Sbjct: 1228 ERRISSPAEETWITC--------EDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAE 1279
Query: 310 LRWEEVCREQQCGS 323
E VC++ CGS
Sbjct: 1280 A--EVVCQQLGCGS 1291
Score = 62.4 bits (150), Expect = 9e-10
Identities = 89/375 (23%), Positives = 141/375 (37%), Gaps = 72/375 (19%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--G 93
RL S+C GQ+E+ + W +C W DP A +C++L+CG LS G
Sbjct: 901 RLVNGKSQCDGQVEINVLGHWGSLCDTHW--------DPEDARVLCRQLSCGTALSTTGG 952
Query: 94 PFLVTYTPQ---SSIICYGQLGSFSNCSHS---RNDMCHSLGLTCLEPQKTTPP------ 141
++ + + C G NC + H ++ + T P
Sbjct: 953 KYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLA 1012
Query: 142 -TTRPPPTTTPEPTA-----PPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQD 195
+ P + PE +A RL+LV G CAG VE Y GTI + D +
Sbjct: 1013 NVSDPYLSAVPEGSALICLEDKRLRLV--DGDSRCAGRVEIYHDGFWGTICDDGWDLSD- 1069
Query: 196 LENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIK 255
+ +C L CG G P W + + +CT +E +
Sbjct: 1070 -AHVVCQKLGCGVAFNATVSAHFGEGSGP-----------IW-LDDLNCTGMESHLWQCP 1116
Query: 256 PQKSGR-------VLALLCSGFQP-KVQSRLVGGSSICEGTVEVRQGAQWAAL--CDSSS 305
+ G+ ++CS F ++ S S C G +EV W ++ + ++
Sbjct: 1117 SRGWGQHDCRHKEDAGVICSEFTALRLYSETETES--CAGRLEVFYNGTWGSVGRRNITT 1174
Query: 306 ARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLF------CP--HQKLSQCHEL-WER 356
A + + VCR+ CG N L T G CP H + QC WER
Sbjct: 1175 AIAGI----VCRQLGCGE-NGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWER 1229
Query: 357 --NSYCKKVFVTCQD 369
+S ++ ++TC+D
Sbjct: 1230 RISSPAEETWITCED 1244
Score = 59.3 bits (142), Expect = 8e-09
Identities = 78/320 (24%), Positives = 121/320 (37%), Gaps = 74/320 (23%)
Query: 26 LSWYDP-DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRL 84
L+ YD D + RL ++C G++E+ ++ W VC W ++ A VC++L
Sbjct: 252 LTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAA--------ADVVCKQL 303
Query: 85 NCGVPLSLG--PFLVTYTP---QSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTT 139
CG L P L + + + C G +C HS ++ CL +
Sbjct: 304 GCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHS-----GTVNFDCLHQNDVS 358
Query: 140 PPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
+ L+L G +C+G VE TI + Q L
Sbjct: 359 VICSDGAD-----------LELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQAL--V 405
Query: 200 LCNNLQCGSFLKHLPETEAG--RAQDPGEPREHQPLPIQWKIQNSSCTSLEH-------- 249
+C L C P + G RA+ E R+ W I + SCT E
Sbjct: 406 VCKQLGC-------PFSVFGSRRAKPSNEARD------IW-INSISCTGNESALWDCTYD 451
Query: 250 ------CFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALC-D 302
CFR+ ++CS + + RLVG S C G +EV+ +W +C D
Sbjct: 452 GKAKRTCFRRSD-------AGVICSD-KADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHD 503
Query: 303 SSSARSSLRWEEVCREQQCG 322
S R++ VC++ CG
Sbjct: 504 RWSTRNA---AVVCKQLGCG 520
Score = 56.2 bits (134), Expect = 7e-08
Identities = 74/311 (23%), Positives = 114/311 (36%), Gaps = 65/311 (20%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCG--VP 89
D + RL +S+C G++EV ++ ++C+ WG + A VC++L CG +
Sbjct: 687 DMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNI--------AEVVCRQLECGSAIR 738
Query: 90 LSLGPFLVTYTPQ---SSIICYGQLGSFSNCSHS--RNDMCH---SLGLTCLEPQKTTPP 141
+S P T S+ C G S +C + CH L C ++
Sbjct: 739 VSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQ---- 794
Query: 142 TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLC 201
PRL C+G VE ++ D + N LC
Sbjct: 795 ---------------PRLV----GADMPCSGRVEVKHADTWRSVC--DSDFSLHAANVLC 833
Query: 202 NNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQW--KIQ-NSSCTSLEHCFRKIKPQK 258
L CG + G+ + W K Q S T L C P+
Sbjct: 834 RELNCGDAISLSVGDHFGKGNG-----------LTWAEKFQCEGSETHLALCPIVQHPED 882
Query: 259 S---GRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEV 315
+ R + ++CS + RLV G S C+G VE+ W +LCD+ R +
Sbjct: 883 TCIHSREVGVVCSRY---TDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDAR--VL 937
Query: 316 CREQQCGSVNS 326
CR+ CG+ S
Sbjct: 938 CRQLSCGTALS 948
Score = 54.3 bits (129), Expect = 2e-07
Identities = 67/320 (20%), Positives = 115/320 (35%), Gaps = 55/320 (17%)
Query: 17 MLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQ 76
+L+ SC S+ D + RL + C G +EV + W VC W ++
Sbjct: 30 LLLNSCFLISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTA-------- 81
Query: 77 ASKVCQRLNCGVPLSLGPFLVTYTPQSSI-----ICYGQLGSFSNCSHSR--NDMCH--- 126
++ VC++L C ++ F T I CYG + C H + C+
Sbjct: 82 STVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGE 141
Query: 127 SLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTIS 186
+G+ C L L G C+G VE GTI
Sbjct: 142 DVGVNCY---------------------GEANLGLRLVDGNNSCSGRVEVKFQERWGTIC 180
Query: 187 YEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTS 246
+ + + +C L C S +G P R P+ + + + +
Sbjct: 181 DDGWN--LNTAAVVCRQLGCPSSF-----ISSGVVNSPAVLR---PIWLDDILCQGNELA 230
Query: 247 LEHCFRK---IKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDS 303
L +C + + L C ++ RLVGG++ C G VE++ +W +C
Sbjct: 231 LWNCRHRGWGNHDCSHNEDVTLTCYD-SSDLELRLVGGTNRCMGRVELKIQGRWGTVCHH 289
Query: 304 SSARSSLRWEEVCREQQCGS 323
++ + VC++ CG+
Sbjct: 290 KWNNAAA--DVVCKQLGCGT 307
Score = 42.7 bits (99), Expect = 8e-04
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 8/65 (12%)
Query: 27 SWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNC 86
+W + + R+ +++C G++E++ W VC SW D ++A VCQ+L C
Sbjct: 1238 TWITCEDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSW--------DLAEAEVVCQQLGC 1289
Query: 87 GVPLS 91
G L+
Sbjct: 1290 GSALA 1294
Score = 32.7 bits (73), Expect = 0.78
Identities = 40/179 (22%), Positives = 65/179 (36%), Gaps = 29/179 (16%)
Query: 44 CQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVP--LSLGPFLVTYTP 101
C G+LEV+ +WG ++ + A VC++L CG +SL P T +
Sbjct: 1152 CAGRLEVFYNG--------TWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGS- 1202
Query: 102 QSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQL 161
F + H CL + P R + E ++
Sbjct: 1203 -----------GFMWVDDIQCPKTHISIWQCL-----SAPWERRISSPAEETWITCEDRI 1246
Query: 162 VAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGR 220
+ G C+G VE + GT+ ++ D + +C L CGS L L + G+
Sbjct: 1247 RVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAE--AEVVCQQLGCGSALAALRDASFGQ 1303
>gi|148539840 deleted in malignant brain tumors 1 isoform a
precursor [Homo sapiens]
Length = 1785
Score = 80.5 bits (197), Expect = 3e-15
Identities = 82/333 (24%), Positives = 122/333 (36%), Gaps = 54/333 (16%)
Query: 30 DPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVP 89
D RL + +CQG++E+ + W VC SW D + A+ VC++L CG
Sbjct: 97 DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWA 148
Query: 90 LSL----------GPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLG--------LT 131
+S GP + + C G +C H+ + H+ G +
Sbjct: 149 MSAPGNAWFGQGSGPIAL-----DDVRCSGHESYLWSCPHN-GWLSHNCGHGEDAGVICS 202
Query: 132 CLEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEA 189
+PQ T P + P + P PT + L L +GG C G VE GT+ +
Sbjct: 203 AAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDY 262
Query: 190 QDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNS---- 242
D T D N +C L CG + + G+ P + R W ++
Sbjct: 263 WD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 243 -SCTSLEHC--------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQ 293
+C E R + +G + + RLV G C+G VEV
Sbjct: 321 HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380
Query: 294 GAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326
W +CD S S VCR+ CG S
Sbjct: 381 RGSWGTVCDDSWDTSDA--NVVCRQLGCGWATS 411
Score = 72.8 bits (177), Expect = 7e-13
Identities = 83/323 (25%), Positives = 119/323 (36%), Gaps = 55/323 (17%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D S A+ VC++L CG S
Sbjct: 364 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTSDANVVCRQLGCGWATSAPGN 415
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQK-TT 139
GP ++ + C G +C H+ ++ HS G+ C +T
Sbjct: 416 ARFGQGSGPIVL-----DDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST 470
Query: 140 PPTTRPPPTTTPEPT--APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDL 196
P P T P T + L L +GG C G VE Y GS GT+ ++ D T D
Sbjct: 471 PSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGS-WGTVCDDSWD-TND- 527
Query: 197 ENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC--- 250
N +C L CG + G+ P + R W ++ S +C
Sbjct: 528 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHS 586
Query: 251 -----------FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAA 299
R + +G + + RLV G C+G VEV W
Sbjct: 587 EDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 646
Query: 300 LCDSSSARSSLRWEEVCREQQCG 322
+CD + VCR+ CG
Sbjct: 647 VCDDYWDTNDA--NVVCRQLGCG 667
Score = 72.4 bits (176), Expect = 9e-13
Identities = 84/323 (26%), Positives = 118/323 (36%), Gaps = 55/323 (17%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC W D + A+ VC++L CG S
Sbjct: 753 RLVNGGDRCQGRVEVLYRGSWGTVCDDYW--------DTNDANVVCRQLGCGWATSAPGN 804
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCHS-LGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q
Sbjct: 805 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 859
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLEN 198
P+ PT+ + L L +GG C G VE Y GS GT+ + D T D N
Sbjct: 860 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGS-WGTVCDDYWD-TND-AN 916
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC----- 250
+C L CG + + G+ P + R W ++ S +C
Sbjct: 917 VVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHHED 975
Query: 251 ----FRKIKPQKSGRV-------LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAA 299
+ Q + R L L G + + RLV G C G VEV W
Sbjct: 976 AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 1035
Query: 300 LCDSSSARSSLRWEEVCREQQCG 322
+CD S + VCR+ CG
Sbjct: 1036 VCDDSWDTNDA--NVVCRQLGCG 1056
Score = 70.5 bits (171), Expect = 3e-12
Identities = 79/324 (24%), Positives = 118/324 (36%), Gaps = 51/324 (15%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +CQG++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 495 RLVNGGDRCQGRVEVLYQGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 546
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQKTTP 140
GP ++ + C G +C H+ ++ HS G+ C Q
Sbjct: 547 ARFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 601
Query: 141 PTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
P+ PT+ + L L +GG C G VE GT+ + D T D N
Sbjct: 602 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWD-TND-ANV 659
Query: 200 LCNNLQCGSFLKHLPETEAGRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHC------ 250
+C L CG + G+ P + R W ++ S +C
Sbjct: 660 VCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS-HNCGHHEDA 718
Query: 251 -----FRKIKPQKSGRVLA---LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCD 302
+ +P S +G + + RLV G C+G VEV W +CD
Sbjct: 719 GVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 778
Query: 303 SSSARSSLRWEEVCREQQCGSVNS 326
+ VCR+ CG S
Sbjct: 779 DYWDTNDA--NVVCRQLGCGWATS 800
Score = 58.2 bits (139), Expect = 2e-08
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 39/210 (18%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC W D + A+ VC++L CG +S
Sbjct: 882 RLVNGGDRCRGRVEVLYQGSWGTVCDDYW--------DTNDANVVCRQLGCGWAMSAPGN 933
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQKTTP 140
GP ++ + C G +C H S N H G+ C Q +
Sbjct: 934 AQFGQGSGPIVL-----DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 988
Query: 141 P------TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQ 194
P TT P T ++ L L +GG C G VE GT+ ++ D T
Sbjct: 989 PRPDTWLTTNLPALTVGSESS---LALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWD-TN 1044
Query: 195 DLENFLCNNLQCGSFLKHLPETEAGRAQDP 224
D N +C L CG + G+ P
Sbjct: 1045 D-ANVVCRQLGCGWAMSAPGNARFGQGSGP 1073
Score = 53.1 bits (126), Expect = 6e-07
Identities = 79/334 (23%), Positives = 117/334 (35%), Gaps = 91/334 (27%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL +C+G++EV + W VC SW D + A+ VC++L CG +S
Sbjct: 1013 RLVNGGDRCRGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMSAPGN 1064
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSH----SRNDMCH-SLGLTCLEPQ--KT 138
GP ++ + C G +C H + N H G+ C Q T
Sbjct: 1065 ARFGQGSGPIVL-----DDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1119
Query: 139 TPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLEN 198
T P TTT P++ +C G + FY+ + SY A
Sbjct: 1120 TTDWWHPTTTTTARPSS-------------NCGGFL-FYASGTFSSPSYPA--------- 1156
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDPG----EPREHQPLPIQW----------------- 237
+ NN +C + E +G + G + H +
Sbjct: 1157 YYPNNAKCVWEI----EVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI 1212
Query: 238 -----KIQNSSCTSLEHCFRK-IKPQKSGRVLALLCSGFQPKVQSRLVGGSS---ICEGT 288
+I SS + FR I Q +G + F RLV +S +C G
Sbjct: 1213 CNDTRQIFTSSYNRMTIHFRSDISFQNTG--FLAWYNSFPSDATLRLVNLNSSYGLCAGR 1270
Query: 289 VEVRQGAQWAALCDSSSARSSLRWEEVCREQQCG 322
VE+ G W +CD S E VCR+ CG
Sbjct: 1271 VEIYHGGTWGTVCDDSWTIQEA--EVVCRQLGCG 1302
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 14/74 (18%)
Query: 24 GRLSWYDP---DFQARLTRSNSK---CQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQA 77
G L+WY+ D RL NS C G++E+Y W VC SW +A
Sbjct: 1241 GFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW--------TIQEA 1292
Query: 78 SKVCQRLNCGVPLS 91
VC++L CG +S
Sbjct: 1293 EVVCRQLGCGRAVS 1306
>gi|44889963 CD163 antigen isoform b [Homo sapiens]
Length = 1121
Score = 70.9 bits (172), Expect = 3e-12
Identities = 80/321 (24%), Positives = 118/321 (36%), Gaps = 83/321 (25%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
D RL ++C G+LEV + W +C W D A+ C++L C ++
Sbjct: 263 DLSLRLVDGVTECSGRLEVRFQGEWGTICDDGW--------DSYDAAVACKQLGCPTAVT 314
Query: 92 -LGPFLVT----YTPQSSIICYGQLGSFSNCSHSR--NDMCH---SLGLTCLEPQKTTPP 141
+G + + S+ C G + C H C+ G+TC +
Sbjct: 315 AIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSD---- 370
Query: 142 TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLE--NF 199
L+L + GG CAG VE L G + D+ L+ +
Sbjct: 371 -----------------LELRLRGGGSRCAGTVEVEIQRLLGKVC----DRGWGLKEADV 409
Query: 200 LCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQN-------SSCTSLEHCFR 252
+C L CGS LK + KIQ SSC E
Sbjct: 410 VCRQLGCGSALK-------------------TSYQVYSKIQATNTWLFLSSCNGNETSLW 450
Query: 253 KIKPQKSGRVLA-------LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSS 305
K + G + + CS + + RLVGG C G VEV+ G W ++CDS
Sbjct: 451 DCKNWQWGGLTCDHYEEAKITCSAHR---EPRLVGGDIPCSGRVEVKHGDTWGSICDSDF 507
Query: 306 ARSSLRWEEVCREQQCGSVNS 326
+ + +CRE QCG+V S
Sbjct: 508 SLEAA--SVLCRELQCGTVVS 526
Score = 67.4 bits (163), Expect = 3e-11
Identities = 78/306 (25%), Positives = 120/306 (39%), Gaps = 63/306 (20%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
D + RL S+C G +EV ++ VC + WG +A VC++L CG L
Sbjct: 370 DLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLK--------EADVVCRQLGCGSALK 421
Query: 92 LGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDM--CHSL---GLTC--LEPQKTTPPTTR 144
+Y S I S+C+ + + C + GLTC E K T R
Sbjct: 422 -----TSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHR 476
Query: 145 PPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNL 204
P +LV G C+G VE G G+I D + + + LC L
Sbjct: 477 EP-------------RLVG--GDIPCSGRVEVKHGDTWGSIC--DSDFSLEAASVLCREL 519
Query: 205 QCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKS---GR 261
QCG+ + L G E Q + L C +P+ + R
Sbjct: 520 QCGTVVSILGGAHFGEGNGQIWAEEFQC--------EGHESHLSLCPVAPRPEGTCSHSR 571
Query: 262 VLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWE-----EVC 316
+ ++CS + + RLV G + CEG VE++ W +LC+S W+ +C
Sbjct: 572 DVGVVCSRY---TEIRLVNGKTPCEGRVELKTLGAWGSLCNS-------HWDIEDAHVLC 621
Query: 317 REQQCG 322
++ +CG
Sbjct: 622 QQLKCG 627
Score = 63.5 bits (153), Expect = 4e-10
Identities = 66/305 (21%), Positives = 109/305 (35%), Gaps = 64/305 (20%)
Query: 17 MLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQ 76
+L+++C S D + RL +KC G++EV +++ W VC+ W +
Sbjct: 33 LLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEA-------- 84
Query: 77 ASKVCQRLNCGVPLSLGPFLVTYTPQSS------IICYGQLGSFSNCSH---SRNDMC-- 125
S +C +L C + P + S + C G + +C H ++ C
Sbjct: 85 VSVICNQLGCPTAIK-APGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143
Query: 126 -HSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGT 184
G+TC + TR GG C+G +E GT
Sbjct: 144 QQDAGVTCSDGSNLEMRLTR---------------------GGNMCSGRIEIKFQGRWGT 182
Query: 185 ISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSC 244
+ + + D + +C L+CGS + + G P W + C
Sbjct: 183 VCDD--NFNIDHASVICRQLECGSAVSFSGSSNFGEGSGP-----------IW-FDDLIC 228
Query: 245 TSLEHCFRKIKPQKSGR-------VLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQW 297
E K Q G+ ++CS + RLV G + C G +EVR +W
Sbjct: 229 NGNESALWNCKHQGWGKHNCDHAEDAGVICSK-GADLSLRLVDGVTECSGRLEVRFQGEW 287
Query: 298 AALCD 302
+CD
Sbjct: 288 GTICD 292
Score = 60.8 bits (146), Expect = 3e-09
Identities = 92/430 (21%), Positives = 155/430 (36%), Gaps = 97/430 (22%)
Query: 34 QARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL- 92
Q RL +C G++E+Y + W +C SW D S A VC++L CG ++
Sbjct: 718 QLRLVNGGGRCAGRVEIYHEGSWGTICDDSW--------DLSDAHVVCRQLGCGEAINAT 769
Query: 93 ---------GPFLVTYTP----QSSII-CYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKT 138
GP + +S I C+ NC H + G+ C E
Sbjct: 770 GSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKED-----AGVICSEFMS- 823
Query: 139 TPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLEN 198
L+L +++ + CAG +E + GT+ + +T
Sbjct: 824 --------------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETT--VG 861
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQK 258
+C L C + G+ +P + +P+ W + N C +
Sbjct: 862 VVCRQLGCA---------DKGKI-NPASLDKAMSIPM-W-VDNVQCPKGPDTLWQCPSSP 909
Query: 259 SGRVLA-------LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLR 311
+ LA + C + RL G + C G VE+ G W +CD S
Sbjct: 910 WEKRLASPSEETWITCDN-----KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDA- 963
Query: 312 WEEVCREQQCG-SVNSYRVLDAGDPT--------------SRGLFCPHQKL--SQCHELW 354
+ VC++ CG ++ +++ + G T S CP ++ S+C
Sbjct: 964 -QVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKE 1022
Query: 355 ERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQ 414
+ C + V + +S I +L VVLL + L + L KK R+++Q
Sbjct: 1023 DAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFF--LTKK-RRQRQ 1079
Query: 415 RQWIGPTGMN 424
R + G N
Sbjct: 1080 RLAVSSRGEN 1089
Score = 60.5 bits (145), Expect = 3e-09
Identities = 108/465 (23%), Positives = 161/465 (34%), Gaps = 124/465 (26%)
Query: 34 QARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS-- 91
+ RL + C+G++E+ W +C+ W D A +CQ+L CGV LS
Sbjct: 582 EIRLVNGKTPCEGRVELKTLGAWGSLCNSHW--------DIEDAHVLCQQLKCGVALSTP 633
Query: 92 ---------------------------------LGPFLVTYTPQSSIICYG-QLGSFSNC 117
LG L +S+IC G Q + S+C
Sbjct: 634 GGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSC 693
Query: 118 SHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRL---QLVAQSGGQHCAGVV 174
+ S SLG TRP T PE +A + QL +GG CAG V
Sbjct: 694 NSS------SLG------------PTRP---TIPEESAVACIESGQLRLVNGGGRCAGRV 732
Query: 175 EFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---------- 224
E Y GTI ++ D + + +C L CG + G P
Sbjct: 733 EIYHEGSWGTICDDSWDLSD--AHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790
Query: 225 GEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS- 283
E R Q W QN C E ++CS F + RL +S
Sbjct: 791 KESRIWQCHSHGWGQQN--CRHKEDA-------------GVICSEF---MSLRLTSEASR 832
Query: 284 -ICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLF- 341
C G +EV W + SS + +++ VCR+ C S ++
Sbjct: 833 EACAGRLEVFYNGAWGTVGKSSMSETTV--GVVCRQLGCADKGKINPASLDKAMSIPMWV 890
Query: 342 ----CPH--QKLSQC-HELWERN--SYCKKVFVTCQD-----PNPAGLA-------AGTV 380
CP L QC WE+ S ++ ++TC + P + G+
Sbjct: 891 DNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSW 950
Query: 381 ASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQ 425
++ L VVC L +K F++ + Q GP +N+
Sbjct: 951 GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNE 995
Score = 42.7 bits (99), Expect = 8e-04
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 8/64 (12%)
Query: 27 SWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNC 86
+W D + RL + C G++E++ W VC SW D A VCQ+L C
Sbjct: 921 TWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSW--------DLDDAQVVCQQLGC 972
Query: 87 GVPL 90
G L
Sbjct: 973 GPAL 976
Score = 37.7 bits (86), Expect = 0.024
Identities = 15/54 (27%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 274 VQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSY 327
++ RL G ++C G +E++ +W +CD + +CR+ +CGS S+
Sbjct: 157 LEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHA--SVICRQLECGSAVSF 208
Score = 32.3 bits (72), Expect = 1.0
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 13/104 (12%)
Query: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPT 336
RLV G + C G VEV+ +W +C++ + ++ +C + C +
Sbjct: 52 RLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAV--SVICNQLGCPTAIKAPGWANSSAG 109
Query: 337 SRGLFCPH-------QKLSQC-HELWERNSYC---KKVFVTCQD 369
S ++ H L C H+ W ++S C + VTC D
Sbjct: 110 SGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD 153
>gi|44662834 CD163 antigen isoform a [Homo sapiens]
Length = 1156
Score = 70.9 bits (172), Expect = 3e-12
Identities = 80/321 (24%), Positives = 118/321 (36%), Gaps = 83/321 (25%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
D RL ++C G+LEV + W +C W D A+ C++L C ++
Sbjct: 263 DLSLRLVDGVTECSGRLEVRFQGEWGTICDDGW--------DSYDAAVACKQLGCPTAVT 314
Query: 92 -LGPFLVT----YTPQSSIICYGQLGSFSNCSHSR--NDMCH---SLGLTCLEPQKTTPP 141
+G + + S+ C G + C H C+ G+TC +
Sbjct: 315 AIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSD---- 370
Query: 142 TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLE--NF 199
L+L + GG CAG VE L G + D+ L+ +
Sbjct: 371 -----------------LELRLRGGGSRCAGTVEVEIQRLLGKVC----DRGWGLKEADV 409
Query: 200 LCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQN-------SSCTSLEHCFR 252
+C L CGS LK + KIQ SSC E
Sbjct: 410 VCRQLGCGSALK-------------------TSYQVYSKIQATNTWLFLSSCNGNETSLW 450
Query: 253 KIKPQKSGRVLA-------LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSS 305
K + G + + CS + + RLVGG C G VEV+ G W ++CDS
Sbjct: 451 DCKNWQWGGLTCDHYEEAKITCSAHR---EPRLVGGDIPCSGRVEVKHGDTWGSICDSDF 507
Query: 306 ARSSLRWEEVCREQQCGSVNS 326
+ + +CRE QCG+V S
Sbjct: 508 SLEAA--SVLCRELQCGTVVS 526
Score = 67.4 bits (163), Expect = 3e-11
Identities = 78/306 (25%), Positives = 120/306 (39%), Gaps = 63/306 (20%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
D + RL S+C G +EV ++ VC + WG +A VC++L CG L
Sbjct: 370 DLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLK--------EADVVCRQLGCGSALK 421
Query: 92 LGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDM--CHSL---GLTC--LEPQKTTPPTTR 144
+Y S I S+C+ + + C + GLTC E K T R
Sbjct: 422 -----TSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHR 476
Query: 145 PPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNL 204
P +LV G C+G VE G G+I D + + + LC L
Sbjct: 477 EP-------------RLVG--GDIPCSGRVEVKHGDTWGSIC--DSDFSLEAASVLCREL 519
Query: 205 QCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKS---GR 261
QCG+ + L G E Q + L C +P+ + R
Sbjct: 520 QCGTVVSILGGAHFGEGNGQIWAEEFQC--------EGHESHLSLCPVAPRPEGTCSHSR 571
Query: 262 VLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWE-----EVC 316
+ ++CS + + RLV G + CEG VE++ W +LC+S W+ +C
Sbjct: 572 DVGVVCSRY---TEIRLVNGKTPCEGRVELKTLGAWGSLCNS-------HWDIEDAHVLC 621
Query: 317 REQQCG 322
++ +CG
Sbjct: 622 QQLKCG 627
Score = 63.5 bits (153), Expect = 4e-10
Identities = 66/305 (21%), Positives = 109/305 (35%), Gaps = 64/305 (20%)
Query: 17 MLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQ 76
+L+++C S D + RL +KC G++EV +++ W VC+ W +
Sbjct: 33 LLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEA-------- 84
Query: 77 ASKVCQRLNCGVPLSLGPFLVTYTPQSS------IICYGQLGSFSNCSH---SRNDMC-- 125
S +C +L C + P + S + C G + +C H ++ C
Sbjct: 85 VSVICNQLGCPTAIK-APGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143
Query: 126 -HSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGT 184
G+TC + TR GG C+G +E GT
Sbjct: 144 QQDAGVTCSDGSNLEMRLTR---------------------GGNMCSGRIEIKFQGRWGT 182
Query: 185 ISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSC 244
+ + + D + +C L+CGS + + G P W + C
Sbjct: 183 VCDD--NFNIDHASVICRQLECGSAVSFSGSSNFGEGSGP-----------IW-FDDLIC 228
Query: 245 TSLEHCFRKIKPQKSGR-------VLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQW 297
E K Q G+ ++CS + RLV G + C G +EVR +W
Sbjct: 229 NGNESALWNCKHQGWGKHNCDHAEDAGVICSK-GADLSLRLVDGVTECSGRLEVRFQGEW 287
Query: 298 AALCD 302
+CD
Sbjct: 288 GTICD 292
Score = 61.2 bits (147), Expect = 2e-09
Identities = 98/470 (20%), Positives = 167/470 (35%), Gaps = 105/470 (22%)
Query: 34 QARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL- 92
Q RL +C G++E+Y + W +C SW D S A VC++L CG ++
Sbjct: 718 QLRLVNGGGRCAGRVEIYHEGSWGTICDDSW--------DLSDAHVVCRQLGCGEAINAT 769
Query: 93 ---------GPFLVTYTP----QSSII-CYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKT 138
GP + +S I C+ NC H + G+ C E
Sbjct: 770 GSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKED-----AGVICSEFMS- 823
Query: 139 TPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLEN 198
L+L +++ + CAG +E + GT+ + +T
Sbjct: 824 --------------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETT--VG 861
Query: 199 FLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQK 258
+C L C + G+ +P + +P+ W + N C +
Sbjct: 862 VVCRQLGCA---------DKGKI-NPASLDKAMSIPM-W-VDNVQCPKGPDTLWQCPSSP 909
Query: 259 SGRVLA-------LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLR 311
+ LA + C + RL G + C G VE+ G W +CD S
Sbjct: 910 WEKRLASPSEETWITCDN-----KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDA- 963
Query: 312 WEEVCREQQCG-SVNSYRVLDAGDPT--------------SRGLFCPHQKL--SQCHELW 354
+ VC++ CG ++ +++ + G T S CP ++ S+C
Sbjct: 964 -QVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKE 1022
Query: 355 ERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQ 414
+ C + V + +S I +L VVLL + L + L KK ++Q
Sbjct: 1023 DAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFF--LTKK---RRQ 1077
Query: 415 RQWIGPTGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSA 464
RQ + + +N+ ++ N + D + NSH SA
Sbjct: 1078 RQRLAVSSRGENL------VHQIQYREMNSCLNADDLDLMNSSENSHESA 1121
Score = 60.5 bits (145), Expect = 3e-09
Identities = 108/465 (23%), Positives = 161/465 (34%), Gaps = 124/465 (26%)
Query: 34 QARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS-- 91
+ RL + C+G++E+ W +C+ W D A +CQ+L CGV LS
Sbjct: 582 EIRLVNGKTPCEGRVELKTLGAWGSLCNSHW--------DIEDAHVLCQQLKCGVALSTP 633
Query: 92 ---------------------------------LGPFLVTYTPQSSIICYG-QLGSFSNC 117
LG L +S+IC G Q + S+C
Sbjct: 634 GGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSC 693
Query: 118 SHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRL---QLVAQSGGQHCAGVV 174
+ S SLG TRP T PE +A + QL +GG CAG V
Sbjct: 694 NSS------SLG------------PTRP---TIPEESAVACIESGQLRLVNGGGRCAGRV 732
Query: 175 EFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---------- 224
E Y GTI ++ D + + +C L CG + G P
Sbjct: 733 EIYHEGSWGTICDDSWDLSD--AHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790
Query: 225 GEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS- 283
E R Q W QN C E ++CS F + RL +S
Sbjct: 791 KESRIWQCHSHGWGQQN--CRHKEDA-------------GVICSEF---MSLRLTSEASR 832
Query: 284 -ICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLF- 341
C G +EV W + SS + +++ VCR+ C S ++
Sbjct: 833 EACAGRLEVFYNGAWGTVGKSSMSETTV--GVVCRQLGCADKGKINPASLDKAMSIPMWV 890
Query: 342 ----CPH--QKLSQC-HELWERN--SYCKKVFVTCQD-----PNPAGLA-------AGTV 380
CP L QC WE+ S ++ ++TC + P + G+
Sbjct: 891 DNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSW 950
Query: 381 ASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQ 425
++ L VVC L +K F++ + Q GP +N+
Sbjct: 951 GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNE 995
Score = 42.7 bits (99), Expect = 8e-04
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 8/64 (12%)
Query: 27 SWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNC 86
+W D + RL + C G++E++ W VC SW D A VCQ+L C
Sbjct: 921 TWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSW--------DLDDAQVVCQQLGC 972
Query: 87 GVPL 90
G L
Sbjct: 973 GPAL 976
Score = 37.7 bits (86), Expect = 0.024
Identities = 15/54 (27%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 274 VQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSY 327
++ RL G ++C G +E++ +W +CD + +CR+ +CGS S+
Sbjct: 157 LEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHA--SVICRQLECGSAVSF 208
Score = 32.3 bits (72), Expect = 1.0
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 13/104 (12%)
Query: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPT 336
RLV G + C G VEV+ +W +C++ + ++ +C + C +
Sbjct: 52 RLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAV--SVICNQLGCPTAIKAPGWANSSAG 109
Query: 337 SRGLFCPH-------QKLSQC-HELWERNSYC---KKVFVTCQD 369
S ++ H L C H+ W ++S C + VTC D
Sbjct: 110 SGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD 153
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 61.6 bits (148), Expect = 2e-09
Identities = 87/362 (24%), Positives = 117/362 (32%), Gaps = 109/362 (30%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--- 92
RL C G+LEV+ W VC W D A+ C++L CG L+
Sbjct: 21 RLADGPHGCAGRLEVWHGGRWGTVCDDGW--------DLRDAAVACRQLGCGGALAAPGG 72
Query: 93 -------GPFLVTYTPQSSIICYGQLGSFSNCSHS--RNDMC---HSLGLTCLEPQ---- 136
GP + S + C G G C H + +C G+ C +
Sbjct: 73 AFFGEGAGPVWL-----SELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANS 127
Query: 137 ------------------KTTPPTTRPPPTTTPEPTAPP--------------------- 157
+ +P T P T P P P
Sbjct: 128 RDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPL 187
Query: 158 ---------RLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGS 208
RL+LV SG CAG +E + G GT+ + D C L CG
Sbjct: 188 LTTGAPRQERLRLV--SGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAA--VACRELGCG- 242
Query: 209 FLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRV------ 262
G PG R W + + C E R GR
Sbjct: 243 ----------GALAAPGGARFGPGAGPVW-MDDVGCGGGEQALRDCPRSPWGRSNCDHSE 291
Query: 263 -LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEV-CREQQ 320
L+C+G P++ RL G C G +EV G +W ++CD + LR V CRE
Sbjct: 292 DAGLVCTGPAPRL--RLADGPHGCAGRLEVWHGGRWGSVCDDA---WDLRDAAVACRELG 346
Query: 321 CG 322
CG
Sbjct: 347 CG 348
Score = 48.1 bits (113), Expect = 2e-05
Identities = 60/242 (24%), Positives = 87/242 (35%), Gaps = 71/242 (29%)
Query: 31 PDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPL 90
P + RL C G+LEV+ W VC +W D A+ C+ L CG L
Sbjct: 300 PAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAW--------DLRDAAVACRELGCGGAL 351
Query: 91 SL----------GPFLVTYTPQSSIICYGQLGSFSNC---------SHSRND---MCHSL 128
+ GP ++ + C G + C H R D +C +
Sbjct: 352 AAPGGAFFGEGSGPIIL-----DDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGM 406
Query: 129 GLTCLEP------QKTTP--PTTRPPPTTT----------PEPTAP------------PR 158
L + P +TP +RPP T T P P +P P+
Sbjct: 407 PLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQ 466
Query: 159 LQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEA 218
L+LVA G C+G +E + GT+ ++ D +C L CG P+ A
Sbjct: 467 LRLVA--GPSKCSGRLEVWHDQRWGTVCDDSWDMRDSA--VVCRELGCGG--PQQPDPAA 520
Query: 219 GR 220
GR
Sbjct: 521 GR 522
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 19/113 (16%)
Query: 34 QARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLG 93
Q RL SKC G+LEV+ W VC SW D ++ VC+ L CG P
Sbjct: 466 QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSW--------DMRDSAVVCRELGCGGPQQPD 517
Query: 94 PFLVTYTPQSSII------CYGQLGSFSNCSHS---RNDMCHS--LGLTCLEP 135
P + + I C G S S+C + +++ H+ +G+TC P
Sbjct: 518 PAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGP 570
Score = 45.8 bits (107), Expect = 9e-05
Identities = 48/191 (25%), Positives = 65/191 (34%), Gaps = 54/191 (28%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPF 95
RL +C G+LEV+ W VC W D A+ C+ L CG L+ P
Sbjct: 199 RLVSGPHRCAGRLEVWHGGRWGTVCDDGW--------DLRDAAVACRELGCGGALA-APG 249
Query: 96 LVTYTPQSSIICYGQLG----------------SFSNCSHSRNDMCHSLGLTCLEPQKTT 139
+ P + + +G SNC HS + GL C P
Sbjct: 250 GARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSED-----AGLVCTGP---- 300
Query: 140 PPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
PRL+L G CAG +E + G G++ +A D
Sbjct: 301 ----------------APRLRLA--DGPHGCAGRLEVWHGGRWGSVCDDAWDLRD--AAV 340
Query: 200 LCNNLQCGSFL 210
C L CG L
Sbjct: 341 ACRELGCGGAL 351
Score = 39.3 bits (90), Expect = 0.008
Identities = 38/131 (29%), Positives = 54/131 (41%), Gaps = 29/131 (22%)
Query: 33 FQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCG-VPLS 91
F+ RL ++C G+LEV+ W VC +W D A+ C L CG V
Sbjct: 770 FRVRLADGPNRCAGRLEVWHAGRWGTVCDDNW--------DLRDATVACWELGCGKVRPR 821
Query: 92 LGPFLVTYTPQSSII------CYGQLGSFSNC---SHSRNDMCH--SLGLTCL------- 133
+G Y P + I C G S S+C + +++ H +GLTC
Sbjct: 822 VGK--THYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDD 879
Query: 134 EPQKTTPPTTR 144
P T PT+R
Sbjct: 880 YPPWTWDPTSR 890
Score = 37.7 bits (86), Expect = 0.024
Identities = 22/49 (44%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 275 QSRLVGGSSICEGTVEVRQGAQWAALCDSS-SARSSLRWEEVCREQQCG 322
Q RLV G S C G +EV +W +CD S R S VCRE CG
Sbjct: 466 QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDS---AVVCRELGCG 511
Score = 34.7 bits (78), Expect = 0.20
Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 7/66 (10%)
Query: 261 RVLALLCS---GFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEV-C 316
RVLA L + G Q + RL G C G +EV G +W +CD LR V C
Sbjct: 2 RVLACLLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDG---WDLRDAAVAC 58
Query: 317 REQQCG 322
R+ CG
Sbjct: 59 RQLGCG 64
Score = 34.7 bits (78), Expect = 0.20
Identities = 15/27 (55%), Positives = 16/27 (59%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T P T PTT P PTTTP+PT P
Sbjct: 1297 TTPHPTMTPDPTTTPYPTTTPDPTTTP 1323
Score = 34.7 bits (78), Expect = 0.20
Identities = 14/23 (60%), Positives = 15/23 (65%)
Query: 134 EPQKTTPPTTRPPPTTTPEPTAP 156
+P T PTT P PTTTP PT P
Sbjct: 1306 DPTTTPYPTTTPDPTTTPHPTTP 1328
Score = 34.3 bits (77), Expect = 0.27
Identities = 15/27 (55%), Positives = 16/27 (59%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T +P T PTT P PTTTP PT P
Sbjct: 1261 TTPQPFTTMQPTTMPHPTTTPHPTTTP 1287
Score = 34.3 bits (77), Expect = 0.27
Identities = 14/27 (51%), Positives = 16/27 (59%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T ++P PTT P PTTTP PT P
Sbjct: 1267 TTMQPTTMPHPTTTPHPTTTPHPTTTP 1293
Score = 33.9 bits (76), Expect = 0.35
Identities = 15/27 (55%), Positives = 15/27 (55%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T P T PTT P PTTTP PT P
Sbjct: 1273 TMPHPTTTPHPTTTPHPTTTPHPTTTP 1299
Score = 33.5 bits (75), Expect = 0.46
Identities = 15/27 (55%), Positives = 15/27 (55%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T P T PTT P PTTTP PT P
Sbjct: 1279 TTPHPTTTPHPTTTPHPTTTPHPTMTP 1305
Score = 32.3 bits (72), Expect = 1.0
Identities = 14/27 (51%), Positives = 15/27 (55%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T P T PTT P PT TP+PT P
Sbjct: 1285 TTPHPTTTPHPTTTPHPTMTPDPTTTP 1311
Score = 31.2 bits (69), Expect = 2.3
Identities = 14/27 (51%), Positives = 14/27 (51%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T P T PT P PTTTP PT P
Sbjct: 1291 TTPHPTTTPHPTMTPDPTTTPYPTTTP 1317
Score = 30.8 bits (68), Expect = 3.0
Identities = 14/24 (58%), Positives = 17/24 (70%), Gaps = 1/24 (4%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPT 154
T ++P TTP +T P PTTTP PT
Sbjct: 1226 TTMQPT-TTPHSTTPHPTTTPHPT 1248
Score = 29.3 bits (64), Expect = 8.6
Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 4/49 (8%)
Query: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEV-CREQQCGSV 324
RL G + C G +EV +W +CD + LR V C E CG V
Sbjct: 773 RLADGPNRCAGRLEVWHAGRWGTVCDDN---WDLRDATVACWELGCGKV 818
Score = 29.3 bits (64), Expect = 8.6
Identities = 12/27 (44%), Positives = 16/27 (59%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T E ++ P+ P PTTTP+PT P
Sbjct: 1135 TVSEYSRSPDPSPSPHPTTTPDPTMAP 1161
>gi|194018748 CD6 molecule [Homo sapiens]
Length = 668
Score = 61.6 bits (148), Expect = 2e-09
Identities = 85/313 (27%), Positives = 113/313 (36%), Gaps = 73/313 (23%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCG---VPLSL 92
RLT +S C G +EV L+ W C W D A VC+ L CG L
Sbjct: 46 RLTNGSSSCSGTVEVRLEASWEPACGALW--------DSRAAEAVCRALGCGGAEAASQL 97
Query: 93 GPFLVTYTP-----QSSIICYGQLGSFSN--CSHSRNDMCHSLGLTCLEPQKTTPPTTRP 145
P P +S+ L CS + +C + C R
Sbjct: 98 APPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRS-------DGRR 150
Query: 146 PPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLE--NFLCNN 203
T E A L+LV GG CAG VE G++ D T DLE + +C
Sbjct: 151 ARVTCAENRA---LRLV--DGGGACAGRVEMLEHGEWGSVC----DDTWDLEDAHVVCRQ 201
Query: 204 LQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLE-------------HC 250
L CG ++ LP G PG H+ +C+ E +C
Sbjct: 202 LGCGWAVQALP----GLHFTPGRGPIHR--------DQVNCSGAEAYLWDCPGLPGQHYC 249
Query: 251 FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSL 310
K + +G V CS Q RL GG+ CEG VEV W +CDS S
Sbjct: 250 GHK---EDAGAV----CSEHQ---SWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEA 299
Query: 311 RWEEVCREQQCGS 323
+ +C+ CG+
Sbjct: 300 K--VLCQSLGCGT 310
Score = 49.3 bits (116), Expect = 8e-06
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 16/105 (15%)
Query: 20 ASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASK 79
A C SW RLT +C+GQ+EV+ + W+ VC W PS+A
Sbjct: 257 AVCSEHQSW-------RLTGGADRCEGQVEVHFRGVWNTVCDSEW--------YPSEAKV 301
Query: 80 VCQRLNCGVPLSLGPFLV-TYTPQSSIICYGQLGSFSNCSHSRND 123
+CQ L CG + L + + + C G+ + SNCS N+
Sbjct: 302 LCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNN 346
Score = 39.7 bits (91), Expect = 0.006
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
Query: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326
RL GSS C GTVEVR A W C + S E VCR CG +
Sbjct: 46 RLTNGSSSCSGTVEVRLEASWEPAC--GALWDSRAAEAVCRALGCGGAEA 93
>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
Length = 343
Score = 59.7 bits (143), Expect = 6e-09
Identities = 55/185 (29%), Positives = 75/185 (40%), Gaps = 24/185 (12%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPF 95
RL +CQG++EV + W VC SW D + A+ VC++L CG + L P
Sbjct: 19 RLVNGGDRCQGRVEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWAM-LAPG 69
Query: 96 LVTYTPQSSII------CYGQLGSFSNCSHS---RNDMCHS--LGLTCLEPQKTTPPTTR 144
+ S I C G +C H+ ++ HS G+ C TP R
Sbjct: 70 NARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPR 129
Query: 145 P-PPTTTPEPTAP-PRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCN 202
P P P L L +GG C G VE GT+ ++ D T D N +C
Sbjct: 130 SWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWD-TND-ANVVCR 187
Query: 203 NLQCG 207
L CG
Sbjct: 188 QLGCG 192
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/188 (26%), Positives = 68/188 (36%), Gaps = 27/188 (14%)
Query: 159 LQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEA 218
L L +GG C G VE GT+ ++ D T D N +C L CG +
Sbjct: 16 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWD-TNDA-NVVCRQLGCGWAMLAPGNARF 73
Query: 219 GRAQDP---GEPREHQPLPIQWKIQNSSCTSLEHCFRK---------------IKPQKSG 260
G+ P + R W ++ S +C I+P+
Sbjct: 74 GQGSGPIVLDDVRCSGNESYLWSCPHNGWLS-HNCGHSEDAGVICSGGPPRTPIRPRSWP 132
Query: 261 RVLALLCSGFQPK--VQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCRE 318
LCS P+ + RLV G C+G VEV W +CD S + VCR+
Sbjct: 133 S--RFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA--NVVCRQ 188
Query: 319 QQCGSVNS 326
CG S
Sbjct: 189 LGCGWATS 196
Score = 37.0 bits (84), Expect = 0.041
Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 269 GFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCG 322
G + + RLV G C+G VEV W +CD S + VCR+ CG
Sbjct: 11 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA--NVVCRQLGCG 62
>gi|5174411 CD5 molecule-like [Homo sapiens]
Length = 347
Score = 54.7 bits (130), Expect = 2e-07
Identities = 72/328 (21%), Positives = 113/328 (34%), Gaps = 62/328 (18%)
Query: 14 LLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWED 73
L +++A C R + RL +C+G++EV K W VC W D
Sbjct: 4 LFSLILAICT-RPGFLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGW--------D 54
Query: 74 PSQASKVCQRLNCGVPLSLGPFLVTYTPQS---------SIICYGQLGSFSNCSHSRNDM 124
+ +C+ L CG S P + Y P + S+ C G + + C
Sbjct: 55 IKDVAVLCRELGCGA-ASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEEVYD 113
Query: 125 C---HSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSL 181
C G +C P+ + P P ++L G HC G VE +
Sbjct: 114 CSHDEDAGASCENPESSFSP-------------VPEGVRLA--DGPGHCKGRVEVKHQNQ 158
Query: 182 GGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQN 241
T+ + +C L CG A Q + PI W +
Sbjct: 159 WYTVCQTGW--SLRAAKVVCRQLGCG---------RAVLTQKRCNKHAYGRKPI-W-LSQ 205
Query: 242 SSCTSLEHCFRKIKPQKSGRVLA-------LLCSGFQPKVQSRLVGGSSICEGTVEVRQG 294
SC+ E + G+ + C + RLVGG ++C G +EV
Sbjct: 206 MSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC---EDPFDLRLVGGDNLCSGRLEVLHK 262
Query: 295 AQWAALCDSSSARSSLRWEEVCREQQCG 322
W ++CD + + VC++ CG
Sbjct: 263 GVWGSVCDDNWGEK--EDQVVCKQLGCG 288
Score = 44.3 bits (103), Expect = 3e-04
Identities = 32/98 (32%), Positives = 41/98 (41%), Gaps = 18/98 (18%)
Query: 30 DPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVP 89
DP F RL ++ C G+LEV K W VC +WG Q VC++L CG
Sbjct: 240 DP-FDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQ--------VVCKQLGCGKS 290
Query: 90 LS--------LGPFLVTYTPQSSIICYGQLGSFSNCSH 119
LS GP V ++ C G+ S C H
Sbjct: 291 LSPSFRDRKCYGPG-VGRIWLDNVRCSGEEQSLEQCQH 327
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVN 325
RLVGG CEG VEV Q QW +CD + +CRE CG+ +
Sbjct: 25 RLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDV--AVLCRELGCGAAS 71
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 48.9 bits (115), Expect = 1e-05
Identities = 77/306 (25%), Positives = 109/306 (35%), Gaps = 45/306 (14%)
Query: 24 GRLSWYDPDFQ---ARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKV 80
G++ W D + RL ++ +G +EVY W VCS W D S AS +
Sbjct: 156 GKVDWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHW--------DDSDASVI 207
Query: 81 CQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRND--MCHS---LGLTCLEP 135
C +L G G + TP S + S C + +C G C P
Sbjct: 208 CHQLQLG-----GKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVC--P 260
Query: 136 QKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHC-AGVVEFYSGSLGGTISYEAQDKTQ 194
QK T + + PT P ++ +GG G VE Y GT+ + D
Sbjct: 261 QKMAAAVTC---SFSHGPTFP----IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDAD 313
Query: 195 DLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSL-EH-CFR 252
+C L K + G P E + + I+ +S EH C
Sbjct: 314 --AEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGH 371
Query: 253 KIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRW 312
K + +G L G RL GG EG +EV QW +CD + L
Sbjct: 372 K---EDAGVSCTPLTDGV-----IRLAGGKGSHEGRLEVYYRGQWGTVCD--DGWTELNT 421
Query: 313 EEVCRE 318
VCR+
Sbjct: 422 YVVCRQ 427
Score = 43.1 bits (100), Expect = 6e-04
Identities = 44/169 (26%), Positives = 62/169 (36%), Gaps = 34/169 (20%)
Query: 164 QSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGS--FLKHLPETEAGRA 221
+ G G VE Y+ + GT+ D + + +C+ LQ G K P + G
Sbjct: 173 RGGKNEFEGTVEVYASGVWGTVCSSHWDDSD--ASVICHQLQLGGKGIAKQTPFSGLGL- 229
Query: 222 QDPGEPREHQPLPIQWKIQNSSCTSLEH----CFRKIK-----PQKSGRVLALLCSGFQP 272
+PI W N C E C + I PQK + S
Sbjct: 230 -----------IPIYWS--NVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT 276
Query: 273 KVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQC 321
RL GGSS+ EG VE+ QW +CD +W++ E C
Sbjct: 277 FPIIRLAGGSSVHEGRVELYHAGQWGTVCDD-------QWDDADAEVIC 318
Score = 30.8 bits (68), Expect = 3.0
Identities = 21/97 (21%), Positives = 37/97 (38%), Gaps = 7/97 (7%)
Query: 33 FQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQ-------WEDPSQASKVCQRLN 85
F RL +K +G++EV++ W +C W ++ P++A +
Sbjct: 498 FPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGE 557
Query: 86 CGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRN 122
P+ + T +S C Q NC HS +
Sbjct: 558 GKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSED 594
Score = 30.0 bits (66), Expect = 5.0
Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 12/51 (23%)
Query: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEE-----VCREQQCG 322
RL GG + EGTVEV W +C S W++ +C + Q G
Sbjct: 171 RLRGGKNEFEGTVEVYASGVWGTVCSS-------HWDDSDASVICHQLQLG 214
Score = 29.3 bits (64), Expect = 8.6
Identities = 26/98 (26%), Positives = 36/98 (36%), Gaps = 15/98 (15%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRL--NCGVPLSLG 93
RL +G+LEVY + W VC W + VC++L G S
Sbjct: 388 RLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELN--------TYVVCRQLGFKYGKQASAN 439
Query: 94 PFLVTYTP--QSSIICYGQLGSFSNCSH---SRNDMCH 126
F + P + C G+ F CS R+D H
Sbjct: 440 HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSH 477
>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
Length = 753
Score = 44.3 bits (103), Expect = 3e-04
Identities = 75/300 (25%), Positives = 111/300 (37%), Gaps = 36/300 (12%)
Query: 45 QGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSS 104
+G +EV L DGW VC + W + +R+N L
Sbjct: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
Query: 105 IICYGQLGSFSNCS---HSRNDMCHSLG-----LTCLEPQKTTPPTTRPPPTTTPEPTAP 156
+ C G S CS + ND G ++C+ P ++ +P
Sbjct: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCV-PGPVYAASSGQKKQQQSKPQGE 304
Query: 157 PRLQLVAQSGGQHCA-GVVEFYSGSLGGTISYEAQDKTQDLE--NFLCNNLQCGSFLKHL 213
R++L GG H G VE S GT+ D+ DL + +C L GS + L
Sbjct: 305 ARVRL---KGGAHPGEGRVEVLKASTWGTVC----DRKWDLHAASVVCRELGFGSAREAL 357
Query: 214 PETEAGRAQDP---GEPR-EHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSG 269
G+ E R Q L + WK + + T+ E C Q +G L +G
Sbjct: 358 SGARMGQGMGAIHLSEVRCSGQELSL-WKCPHKNITA-EDCSHS---QDAGVRCNLPYTG 412
Query: 270 FQPKVQSRLVGGSSICEGTVEVRQGA----QWAALCDSSSARSSLRWEEVCREQQCGSVN 325
+ ++ RL GG S EG VEV+ G +W +C +L CR+ G N
Sbjct: 413 AETRI--RLSGGRSQHEGRVEVQIGGPGPLRWGLICGDD--WGTLEAMVACRQLGLGYAN 468
Score = 32.7 bits (73), Expect = 0.78
Identities = 30/108 (27%), Positives = 45/108 (41%), Gaps = 23/108 (21%)
Query: 271 QPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWE-----EVCREQQCGSVN 325
Q + + RL GG+ EG VEV + + W +CD +W+ VCRE GS
Sbjct: 302 QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDR-------KWDLHAASVVCRELGFGSA- 353
Query: 326 SYRVLDAGDPTSRGLFCPHQKLSQCH----ELWERNSYCKKVFVTCQD 369
R +G +G+ H +C LW+ C +T +D
Sbjct: 354 --REALSGARMGQGMGAIHLSEVRCSGQELSLWK----CPHKNITAED 395
>gi|69354859 ADAM metallopeptidase domain 8 precursor [Homo sapiens]
Length = 856
Score = 37.7 bits (86), Expect = 0.024
Identities = 35/168 (20%), Positives = 64/168 (38%), Gaps = 10/168 (5%)
Query: 313 EEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNP 372
E+VC + +C ++ YR + C H++ CH W +C K+
Sbjct: 594 EKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGW-APPHCAKLLTEVH---- 648
Query: 373 AGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP-TGMNQNMSFHR 431
A + V +++ ++L VVL+ + G + Y+K + + + P T M ++
Sbjct: 649 AASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRN----VAPKTTMGRSNPLFH 704
Query: 432 NHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQP 479
+ V + P S E + +PA AL R P
Sbjct: 705 QAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAP 752
>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
sapiens]
Length = 451
Score = 37.0 bits (84), Expect = 0.041
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 7/53 (13%)
Query: 272 PKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSV 324
P + RLVGGS EG VE+ QW +CD RWE + C S+
Sbjct: 346 PFTKVRLVGGSGPHEGRVEILHSGQWGTICDD-------RWEVRVGQVVCRSL 391
>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
Length = 756
Score = 35.0 bits (79), Expect = 0.16
Identities = 31/88 (35%), Positives = 39/88 (44%), Gaps = 23/88 (26%)
Query: 243 SCTSLEHCFR--KIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL 300
SC + H FR K KPQ+ G +P+V RL G+ + EG VEV QW +
Sbjct: 285 SCVAGPH-FRPPKTKPQRKGSWAE------EPRV--RLRSGAQVGEGRVEVLMNRQWGTV 335
Query: 301 CDSSSARSSLRW-----EEVCREQQCGS 323
CD RW VCR+ GS
Sbjct: 336 CDH-------RWNLISASVVCRQLGFGS 356
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 34.3 bits (77), Expect = 0.27
Identities = 13/17 (76%), Positives = 14/17 (82%)
Query: 141 PTTRPPPTTTPEPTAPP 157
P RPP TTTP+PTAPP
Sbjct: 449 PEPRPPTTTTPQPTAPP 465
>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
Length = 774
Score = 33.9 bits (76), Expect = 0.35
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 271 QPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGS 323
QP V RL GG+ I EG VEV + +W +CD S VCRE GS
Sbjct: 323 QPLV--RLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSA--SVVCRELGFGS 371
Score = 32.0 bits (71), Expect = 1.3
Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 27/118 (22%)
Query: 36 RLTRSNSKCQGQLEVYLKDG----WHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
RL + +G++EV ++ W MVC Q+WG +A VC++L G +
Sbjct: 436 RLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWG--------IVEAMVVCRQLGLGFASN 487
Query: 92 L--------GPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMC-------HSLGLTCLE 134
G S + C G S ++C H D+ + G+ C E
Sbjct: 488 AFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSE 545
>gi|154426272 hypothetical protein LOC54540 [Homo sapiens]
Length = 789
Score = 33.9 bits (76), Expect = 0.35
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 5/80 (6%)
Query: 74 PSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCL 133
P+QAS+ C P + GP ++ P +S+ FS CSH + C G C
Sbjct: 174 PAQASE-CPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHC---GGHCS 229
Query: 134 EPQKTTPPTTRPPPTTTPEP 153
P PP+++P P+T +P
Sbjct: 230 GP-LLPPPSSQPLPSTHRDP 248
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 33.5 bits (75), Expect = 0.46
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 3/78 (3%)
Query: 140 PPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199
PP PPP + PP L +S G C S S G T S+ T D
Sbjct: 598 PPPPPPPPLPEAASSPPPAPPLPLESAGPGCG--QRRSSSSTGSTKSFNMMSPTGDNSEL 655
Query: 200 LCNNLQCGSFLKHLPETE 217
L ++ G LK P+++
Sbjct: 656 LA-EIKAGKSLKPTPQSK 672
>gi|22538450 phosphatidylinositol glycan anchor biosynthesis, class
Q isoform 2 [Homo sapiens]
Length = 581
Score = 33.5 bits (75), Expect = 0.46
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 346 KLSQCHELWERNSYCKKVFVTCQDPNPAGL--AAGTVASIILALVLLVVLL 394
KLS C +L R + +F T + NPA L A TVAS++L + L ++LL
Sbjct: 243 KLSTCEQLRHRLEHLTLIFSTRKAENPAQLMRKANTVASVLLDVALGLMLL 293
>gi|22538453 phosphatidylinositol glycan anchor biosynthesis, class
Q isoform 1 [Homo sapiens]
Length = 760
Score = 33.5 bits (75), Expect = 0.46
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 346 KLSQCHELWERNSYCKKVFVTCQDPNPAGL--AAGTVASIILALVLLVVLL 394
KLS C +L R + +F T + NPA L A TVAS++L + L ++LL
Sbjct: 243 KLSTCEQLRHRLEHLTLIFSTRKAENPAQLMRKANTVASVLLDVALGLMLL 293
>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
Length = 495
Score = 33.5 bits (75), Expect = 0.46
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 3/72 (4%)
Query: 268 SGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNS- 326
SG + + RLV GS EG VEV +W +CD + + VCR V
Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKD--GDVVCRMLGFRGVEEV 442
Query: 327 YRVLDAGDPTSR 338
YR G T R
Sbjct: 443 YRTARFGQGTGR 454
>gi|5031863 galectin 3 binding protein [Homo sapiens]
Length = 585
Score = 33.1 bits (74), Expect = 0.60
Identities = 30/123 (24%), Positives = 43/123 (34%), Gaps = 28/123 (22%)
Query: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNC----- 86
D RL + QG++E++ + W VC W D + AS VC+ L
Sbjct: 21 DGDMRLADGGATNQGRVEIFYRGQWGTVCDNLW--------DLTDASVVCRALGFENATQ 72
Query: 87 ----------GVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQ 136
P+ L T T S C SNC H R+ G+ C
Sbjct: 73 ALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERD-----AGVVCTNET 127
Query: 137 KTT 139
++T
Sbjct: 128 RST 130
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 33.1 bits (74), Expect = 0.60
Identities = 13/27 (48%), Positives = 16/27 (59%)
Query: 135 PQKTTPPTTRPPPTTTPEPTAPPRLQL 161
P PP PPP P P+APP++QL
Sbjct: 1998 PPPPPPPPPPPPPPPPPPPSAPPQVQL 2024
Score = 29.6 bits (65), Expect = 6.6
Identities = 12/27 (44%), Positives = 13/27 (48%)
Query: 131 TCLEPQKTTPPTTRPPPTTTPEPTAPP 157
T P + PPT PPP P P PP
Sbjct: 1985 TVSTPLQAPPPTPPPPPPPPPPPPPPP 2011
>gi|22212927 nuclear transcription factor, X-box binding 1 isoform 3
[Homo sapiens]
Length = 833
Score = 32.7 bits (73), Expect = 0.78
Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 22/103 (21%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASK--VCQRLNCGVPLSLG 93
R+T CQ V+ H+ C + W RS D + CQ ++ VP
Sbjct: 366 RVTAPVWSCQSCYHVF-----HLNCIKKWARSPASQADGQSGWRCPACQNVSAHVPN--- 417
Query: 94 PFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQ 136
TYT C+ G N SRN++ HS G C + Q
Sbjct: 418 ----TYT------CF--CGKVKNPEWSRNEIPHSCGEVCRKKQ 448
>gi|22212925 nuclear transcription factor, X-box binding 1 isoform 2
[Homo sapiens]
Length = 1024
Score = 32.7 bits (73), Expect = 0.78
Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 22/103 (21%)
Query: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASK--VCQRLNCGVPLSLG 93
R+T CQ V+ H+ C + W RS D + CQ ++ VP
Sbjct: 366 RVTAPVWSCQSCYHVF-----HLNCIKKWARSPASQADGQSGWRCPACQNVSAHVPN--- 417
Query: 94 PFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQ 136
TYT C+ G N SRN++ HS G C + Q
Sbjct: 418 ----TYT------CF--CGKVKNPEWSRNEIPHSCGEVCRKKQ 448
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,030,685
Number of Sequences: 37866
Number of extensions: 1186460
Number of successful extensions: 9381
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 8117
Number of HSP's gapped (non-prelim): 1061
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.