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Search of human proteins with 16554562
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16554562 caspase recruitment domain protein 9 isoform 2
[Homo sapiens]
(492 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo... 965 0.0
gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo... 942 0.0
gi|157743265 caspase recruitment domain family, member 11 [Homo ... 370 e-102
gi|51093861 caspase recruitment domain protein 10 [Homo sapiens] 283 3e-76
gi|13129124 caspase recruitment domain protein 14 isoform 1 [Hom... 180 3e-45
gi|16507955 caspase recruitment domain protein 14 isoform 2 [Hom... 79 1e-14
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 72 2e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 69 1e-11
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 68 2e-11
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 65 1e-10
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 65 1e-10
gi|31982906 cingulin-like 1 [Homo sapiens] 65 1e-10
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 65 1e-10
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 65 2e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 64 2e-10
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 64 2e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 2e-10
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 64 2e-10
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 64 3e-10
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 63 5e-10
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 63 7e-10
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 63 7e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 62 9e-10
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 62 2e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 62 2e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 62 2e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 62 2e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 62 2e-09
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 62 2e-09
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 61 3e-09
>gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo
sapiens]
Length = 492
Score = 965 bits (2495), Expect = 0.0
Identities = 492/492 (100%), Positives = 492/492 (100%)
Query: 1 MSDYENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRK 60
MSDYENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRK
Sbjct: 1 MSDYENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRK 60
Query: 61 VGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLM 120
VGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLM
Sbjct: 61 VGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLM 120
Query: 121 TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKE 180
TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKE
Sbjct: 121 TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKE 180
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ
Sbjct: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
Query: 241 RPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
RPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT
Sbjct: 241 RPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
Query: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA
Sbjct: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
Query: 361 IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET 420
IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET
Sbjct: 361 IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET 420
Query: 421 LVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQPFAALHQEQVLRNPHDA 480
LVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQPFAALHQEQVLRNPHDA
Sbjct: 421 LVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQPFAALHQEQVLRNPHDA 480
Query: 481 GPAGLPGIGAVC 492
GPAGLPGIGAVC
Sbjct: 481 GPAGLPGIGAVC 492
>gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo
sapiens]
Length = 536
Score = 942 bits (2434), Expect = 0.0
Identities = 481/481 (100%), Positives = 481/481 (100%)
Query: 1 MSDYENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRK 60
MSDYENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRK
Sbjct: 1 MSDYENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRK 60
Query: 61 VGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLM 120
VGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLM
Sbjct: 61 VGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLM 120
Query: 121 TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKE 180
TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKE
Sbjct: 121 TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKE 180
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ
Sbjct: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
Query: 241 RPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
RPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT
Sbjct: 241 RPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
Query: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA
Sbjct: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
Query: 361 IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET 420
IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET
Sbjct: 361 IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET 420
Query: 421 LVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQPFAALHQEQVLRNPHDA 480
LVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQPFAALHQEQVLRNPHDA
Sbjct: 421 LVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQPFAALHQEQVLRNPHDA 480
Query: 481 G 481
G
Sbjct: 481 G 481
>gi|157743265 caspase recruitment domain family, member 11 [Homo
sapiens]
Length = 1154
Score = 370 bits (949), Expect = e-102
Identities = 206/480 (42%), Positives = 304/480 (63%), Gaps = 33/480 (6%)
Query: 1 MSDY-----ENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLV 55
M DY + +D W +E R L+ I+P+++TPYLRQCKV++ DE++VL+ P L
Sbjct: 8 MDDYMETLKDEEDALWENVECNRHMLSRYINPAKLTPYLRQCKVIDEQDEDEVLNAPMLP 67
Query: 56 IRKRKVGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGL 115
+ + G LLDIL G +GYV FLESLE YYP+LYK VTGKEP R FS I+ G GL
Sbjct: 68 SKINRAGRLLDILHTKGQRGYVVFLESLEFYYPELYKLVTGKEPTRRFSTIVVEEGHEGL 127
Query: 116 TQLLMTEVMKLQKKVQ-------DLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEEC 168
T LM EV+KLQ++++ +L A L +D K++ + L QER ++KEE
Sbjct: 128 THFLMNEVIKLQQQMKAKDLQRCELLARLRQLEDEKKQMTLTRVELLTFQERYYKMKEER 187
Query: 169 EAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVER 228
++ + EL + K++NY+LAMR A SEEK A+MR+RDLQLEIDQLKH L K E++CK+ER
Sbjct: 188 DSYNDELVKVKDDNYNLAMRYAQLSEEKNMAVMRSRDLQLEIDQLKHRLNKMEEECKLER 247
Query: 229 KHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKL---DRSSPYIQVLEE 285
+LKL++ +E RP +E + EL++E +L+ + QEL++ +Q GK D + +LE
Sbjct: 248 NQSLKLKNDIENRPKKEQVLELERENEMLKTKNQELQSIIQAGKRSLPDSDKAILDILEH 307
Query: 286 DWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEA 345
D ++AL D QE N I++L+++ RQ E R + +EEKE EL+C L KD +MYK R+
Sbjct: 308 DRKEALEDRQELVNRIYNLQEEARQAEELRDKYLEEKEDLELKCSTLGKDCEMYKHRMNT 367
Query: 346 ILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQ 405
++LQ+EEV ERDQA +R+E Q+++ L EKD RKQ+REL EK DE+++++ + EA
Sbjct: 368 VMLQLEEVERERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELEEKNDEMRIEMVRREAC 427
Query: 406 LLAVEGRLRR-------------QQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDK 452
++ +E +LRR + L ++S D D SPR + Q+ +D+ S++
Sbjct: 428 IVNLESKLRRLSKDSNNLDQSLPRNLPVTIISQDFGDASPRTN-----GQEADDSSTSEE 482
>gi|51093861 caspase recruitment domain protein 10 [Homo sapiens]
Length = 1032
Score = 283 bits (723), Expect = 3e-76
Identities = 177/493 (35%), Positives = 274/493 (55%), Gaps = 29/493 (5%)
Query: 7 DDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRKVGVLLD 66
+D W +EG R L ++P+++TPYLRQC+V++ DEE+VLS R + G L+D
Sbjct: 24 EDALWERIEGVRHRLARALNPAKLTPYLRQCRVIDEQDEEEVLSTYRFPCRVNRTGRLMD 83
Query: 67 ILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKL 126
IL+ G +GY AFLE+LE YYP+ + +TG+EPA+ SMI+D G GLTQ LMTEV +L
Sbjct: 84 ILRCRGKRGYEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRL 143
Query: 127 Q-------KKVQDLTA--LLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKR 177
+ ++ Q L A + ++ E R++D ++ QER QRL+E+ EAGS EL R
Sbjct: 144 REARKSQLQREQQLQARGRVLEEERAGLEQRLRDQ--QQAQERCQRLREDWEAGSLELLR 201
Query: 178 CKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERK-------- 229
K+ENY +AMRLA SEEK +A++R+RDLQL +DQLK + + E++C + R+
Sbjct: 202 LKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPPPGA 261
Query: 230 -HTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSP-----YIQVL 283
K + ++ + +L+ EL+ E L A ++EL+ +Q+ +P + +L
Sbjct: 262 EEKEKEKEKEKEPDNVDLVSELRAENQRLTASLRELQEGLQQEASRPGAPGSERILLDIL 321
Query: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343
E DWR+A QE + +++ +L+ E R + ++E E L+ L+KD +YK R+
Sbjct: 322 EHDWREAQDSRQELCQKLHAVQGELQWAEELRDQYLQEMEDLRLKHRTLQKDCDLYKHRM 381
Query: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403
+L Q+EE+ ERDQAI +R+ + Q+++ L EKD RKQVR L + DEL + E
Sbjct: 382 ATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTLTSLE 441
Query: 404 AQLLAVEGRLRRQQ----LETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGG 459
+E +L+R Q L+ S L P L + + + + GG
Sbjct: 442 GTKALLEVQLQRAQGGTCLKACASSHSLCSNLSSTWSLSEFPSPLGGPEATGEAAVMGGP 501
Query: 460 SPKQPFAALHQEQ 472
P A E+
Sbjct: 502 EPHNSEEATDSEK 514
>gi|13129124 caspase recruitment domain protein 14 isoform 1 [Homo
sapiens]
Length = 1004
Score = 180 bits (456), Expect = 3e-45
Identities = 143/464 (30%), Positives = 222/464 (47%), Gaps = 38/464 (8%)
Query: 6 NDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRKVGVLL 65
+++ W ++E R + I PSR+TPYLRQ KVL DEE+VL P L + G LL
Sbjct: 15 DEETLWEMMESHRHRIVRCICPSRLTPYLRQAKVLCQLDEEEVLHSPRLTNSAMRAGHLL 74
Query: 66 DILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMK 125
D+L+ G G +AFLESL+ + P +Y VTG +P FS S LT+ L +
Sbjct: 75 DLLKTRGKNGAIAFLESLKFHNPDVYTLVTGLQPDVDFSNFSGLMETSKLTECLAGAIGS 134
Query: 126 LQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQ----------RLKEECEAGSREL 175
LQ ++L K+ ++ + L + R + R+K E A E+
Sbjct: 135 LQ---EELNQEKGQKEVLLRRCQQLQEHLGLAETRAEGLHQLEADHSRMKREVSAHFHEV 191
Query: 176 KRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAE--DDCKVERKHTLK 233
R K+E L++ ++ +EK A R R LQ E+ LK L +A C++E +
Sbjct: 192 LRLKDEMLSLSLHYSNALQEKELAASRCRSLQEELYLLKQELQRANMVSSCELELQEQ-S 250
Query: 234 LRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRD 293
LR A +Q E L L++E L++ L +LE+ +A
Sbjct: 251 LRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-------------DILEQSLDEARGS 297
Query: 294 HQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEV 353
QE I SLR+ E +R + EEKE LQ + ++Y++++ A+ Q+ E+
Sbjct: 298 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 357
Query: 354 AIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQ---LLAVE 410
ERDQA + R+ + ++ L EKD+LR+QV EL ++ EL+ Q+ Q +A+ +L E
Sbjct: 358 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 417
Query: 411 GRLRR---QQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSD 451
R R ++ + LV + PR + SL E LSD
Sbjct: 418 ARTREPCPREKQRLVRMHAI---CPRDDSDCSLVSSTESQLLSD 458
>gi|16507955 caspase recruitment domain protein 14 isoform 2 [Homo
sapiens]
Length = 434
Score = 78.6 bits (192), Expect = 1e-14
Identities = 68/234 (29%), Positives = 111/234 (47%), Gaps = 23/234 (9%)
Query: 224 CKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVL 283
C++E + LR A +Q E L L++E L++ L +L
Sbjct: 5 CELELQEQ-SLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-------------DIL 50
Query: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343
E+ +A QE I SLR+ E +R + EEKE LQ + ++Y++++
Sbjct: 51 EQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV 110
Query: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403
A+ Q+ E+ ERDQA + R+ + ++ L EKD+LR+QV EL ++ EL+ Q+ Q +
Sbjct: 111 NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170
Query: 404 AQ---LLAVEGRLRR---QQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSD 451
A+ +L E R R ++ + LV + PR + SL E LSD
Sbjct: 171 AEPPGVLKQEARTREPCPREKQRLVRMHAI---CPRDDSDCSLVSSTESQLLSD 221
Score = 38.9 bits (89), Expect = 0.011
Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 15/133 (11%)
Query: 158 QERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSL 217
QE+ R + E+G EL R KEEN L L EK L+ +D+ + S
Sbjct: 10 QEQSLRTASDQESGDEELNRLKEENEKL-RSLTFSLAEKDI-------LEQSLDEARGSR 61
Query: 218 MKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSS 277
+ VER H+L+ R +R +E WE ++E+ LLQ + ++ + K++
Sbjct: 62 QEL-----VERIHSLRERAVAAER-QREQYWE-EKEQTLLQFQKSKMACQLYREKVNALQ 114
Query: 278 PYIQVLEEDWRQA 290
+ L+++ QA
Sbjct: 115 AQVCELQKERDQA 127
Score = 29.6 bits (65), Expect = 6.5
Identities = 35/160 (21%), Positives = 72/160 (45%), Gaps = 14/160 (8%)
Query: 112 ESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAG 171
ESG +L + + +K++ LT L+ KD + L ++ ER+ L+E A
Sbjct: 21 ESGDEEL--NRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAA 78
Query: 172 SRELKRCKEENYDLAMRLAHQSEEKGAALMRNR--DLQLEIDQL---KHSLMKAEDDCKV 226
R+ ++ EE ++ Q + L R + LQ ++ +L + A D +
Sbjct: 79 ERQREQYWEEKEQTLLQF--QKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQR 136
Query: 227 ERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEA 266
E +L +E+ + ++EL + L+ ++++L+A
Sbjct: 137 EISQSL-----VEKDSLRRQVFELTDQVCELRTQLRQLQA 171
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 71.6 bits (174), Expect = 2e-12
Identities = 58/305 (19%), Positives = 153/305 (50%), Gaps = 16/305 (5%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKE----LRVKDSLLRKHQERVQRLKEECEAGSRELKR 177
++ + ++K+Q+ + +++ I+E +R ++ ++ + +E+++R +E +++R
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
Query: 178 CKEENYDLAMRLAHQSEE--KGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLR 235
+E ++ ++ E+ + + + + E ++++ + E + K+ R+ K+R
Sbjct: 368 LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE-KIR 426
Query: 236 HAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQ 295
E+ QE Q+EK Q +++E E ++ ++ R I+ EE WRQ + H+
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE 486
Query: 296 EQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAI 355
++ +RK + + + +++E Q + + + +++ E I Q E++
Sbjct: 487 QE-----KIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR- 540
Query: 356 ERDQAIATREELHAQHARGLQEKDALRKQ---VRELGEKADELQLQVFQCEAQLLAVEGR 412
E+++ + +EE + +QE++ +R+Q +RE EK E + ++ + E ++ E +
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
Query: 413 LRRQQ 417
+R Q+
Sbjct: 601 IREQE 605
Score = 67.4 bits (163), Expect = 3e-11
Identities = 83/332 (25%), Positives = 150/332 (45%), Gaps = 33/332 (9%)
Query: 123 VMKLQKKVQDLTALLSSKDDFIKELRVKDSLL----RKHQERVQRLKEECEAGSRELKRC 178
V +L+ + +DL + L F EL S + +K ++ L +E +A S EL R
Sbjct: 153 VKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRN 212
Query: 179 KEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAM 238
+ +L + A E+ ++QL + +LK L +A+ L L
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK----------LLLPQQQ 262
Query: 239 EQRPSQELLWELQQEKALLQARVQELEA-----SVQEGKLDRSSPYIQVLEEDWRQALRD 293
Q + L ELQ A LQA+V+E E QE K+ R IQ +W + +
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ----EWEEKI-- 316
Query: 294 HQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEV 353
QEQ I + +R+ E + R +E+ M+E + R++ M++ E + ++EE+
Sbjct: 317 -QEQEEKIREQEEKIREQEEKMRR--QEEMMWEKEEKMRRQEEMMWEK--EEKMRRLEEM 371
Query: 354 AIERDQAIATREE-LHAQH-ARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEG 411
E+++ I EE +H Q R +EK +++RE EK E + ++++ E ++ E
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEE 430
Query: 412 RLRRQQLETLVLSSDLEDGSPRRSQELSLPQD 443
++R Q+ + + + R +E Q+
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462
Score = 33.1 bits (74), Expect = 0.59
Identities = 33/180 (18%), Positives = 84/180 (46%), Gaps = 25/180 (13%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFI----KELRVKDSLLRKHQERVQRLKEECEAGSRELKR 177
+V + ++K+ D + +++ + +++R ++ +R+ +E++ R +EE E
Sbjct: 496 KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI-REQEEMMQEQEEKMG 554
Query: 178 CKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHA 237
+EE ++ Q E + R+ + +I + K + + E+ + + +
Sbjct: 555 EQEEKMQEQEKMRRQEE-------KIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEM 607
Query: 238 MEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQ 297
M+++ +E +WE +++ + ++QE QE K+ R E+ W Q +R Q++
Sbjct: 608 MQEQ--EEKMWEQEEKMCEQEEKMQE-----QEEKMRRQE------EKMWEQEVRLRQQE 654
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 68.9 bits (167), Expect = 1e-11
Identities = 67/347 (19%), Positives = 169/347 (48%), Gaps = 19/347 (5%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKE----LRVKDSLLRKHQERVQRLKEECEAGSRELKR 177
++ + ++K+Q+ + +++ I+E +R ++ ++ + +E+++R +E +++R
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 428
Query: 178 CKEENYDLAMRLAHQSEE--KGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLR 235
+E ++ ++ E+ + + + + E ++++ + E + K+ R+ K+R
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE-KIR 487
Query: 236 HAMEQ-RPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDH 294
E+ R +E +W Q+EK Q +++E E ++ ++ R I+ EE WRQ + H
Sbjct: 488 EQEEKIREQEEKMWR-QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Query: 295 QEQANTIFSLRKDLRQGEA---RRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQME 351
+++ K RQ E + + E++E Q +R+ + +++ E I + E
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI-REQE 605
Query: 352 EVAIERDQAIATREELHAQHARGLQE-KDALRKQ---VRELGEKADELQLQVFQCEAQLL 407
E+ E+++ + +EE + +QE ++ +R+Q +RE +K E + ++ + E +
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 408 AVEGRLRRQQLETLVLSSDLEDGSP--RRSQELSLPQDLEDTQLSDK 452
E ++ Q+ + +++ RR +E Q++ Q +K
Sbjct: 666 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712
Score = 66.2 bits (160), Expect = 6e-11
Identities = 80/306 (26%), Positives = 141/306 (46%), Gaps = 33/306 (10%)
Query: 123 VMKLQKKVQDLTALLSSKDDFIKELRVKDSLL----RKHQERVQRLKEECEAGSRELKRC 178
V +L+ + +DL + L F EL S + +K ++ L +E +A S EL R
Sbjct: 214 VKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRN 273
Query: 179 KEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAM 238
+ +L + A E+ ++QL + +LK L +A+ L L
Sbjct: 274 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK----------LLLPQQQ 323
Query: 239 EQRPSQELLWELQQEKALLQARVQELEA-----SVQEGKLDRSSPYIQVLEEDWRQALRD 293
Q + L ELQ A LQA+V+E E QE K+ R IQ +W + +
Sbjct: 324 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ----EWEEKI-- 377
Query: 294 HQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEV 353
QEQ I + +R+ E + R +E+ M+E + R++ M++ E + + EE+
Sbjct: 378 -QEQEEKIREQEEKIREQEEKMRR--QEEMMWEKEEKMRRQEEMMWEK--EEKMRRQEEM 432
Query: 354 AIERDQAIATREE-LHAQH-ARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEG 411
E+++ I EE +H Q R +EK +++RE EK E + ++++ E ++ E
Sbjct: 433 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEE 491
Query: 412 RLRRQQ 417
++R Q+
Sbjct: 492 KIREQE 497
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 67.8 bits (164), Expect = 2e-11
Identities = 90/363 (24%), Positives = 166/363 (45%), Gaps = 40/363 (11%)
Query: 114 GLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSR 173
G Q L +V+ LQ K++ A L +D +L + +++LR+H+ VQ+LKE+ EA +R
Sbjct: 783 GEVQRLQAQVVDLQAKMR---AALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNR 839
Query: 174 ----ELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERK 229
EL +C E L A +++++ L R LQ E+ Q K S ++ ++E
Sbjct: 840 AHVQELLQCSEREGALQEERADEAQQREEEL---RALQEELSQAKCS----SEEAQLEHA 892
Query: 230 HTLKLRHAMEQRPSQ------ELLWELQQEKALLQARVQELE-----ASVQEGKLDRSSP 278
+ H ++ L E ++ + L VQEL+ AS + L+R
Sbjct: 893 ELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVA 952
Query: 279 YIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKM 338
+Q +E ++ L+ + A ++ L+ L Q E +R + ++E EL L + +++
Sbjct: 953 GLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAE-QRAQSLQEAAHQELNTLKFQLSAEI 1011
Query: 339 --YKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQ 396
Y+ R++ EE R Q EE Q + + L+ ++GEK
Sbjct: 1012 MDYQSRLKN---AGEECKSLRGQL----EEQGRQLQAAEEAVEKLKATQADMGEKLSCTS 1064
Query: 397 LQVFQCEAQLLA--VEGRLRRQQLETLVLSSDLEDGSPRRSQELS-LPQDLEDTQLSDKG 453
+ +C+A +L EG R+ LE +LE + + + + L Q++ + + +D+
Sbjct: 1065 NHLAECQAAMLRKDKEGAALREDLER--TQKELEKATTKIQEYYNKLCQEVTNRERNDQK 1122
Query: 454 CLA 456
LA
Sbjct: 1123 MLA 1125
Score = 50.8 bits (120), Expect = 3e-06
Identities = 85/364 (23%), Positives = 156/364 (42%), Gaps = 54/364 (14%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
E +L +++Q+L A SS ++ + ELR + ++ QE + L++E + +R+L+ + +
Sbjct: 465 EADQLWRRLQELLAHTSSWEEELAELRREK---KQQQEEKELLEQEVRSLTRQLQFLETQ 521
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKV--ERKHTL-----KL 234
++ ++ E+K + L ++ L+ + V E+ L L
Sbjct: 522 LAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSSL 581
Query: 235 RHAM-----EQRPSQEL------LWELQQEKALLQARVQELEASVQE--GKLDRSSPYIQ 281
+ A EQR QE + E QE+ L QA +ELE +Q G+ +Q
Sbjct: 582 QEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQAN-RELEKELQNVVGRNQLLEGKLQ 640
Query: 282 VLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKD 341
L+ D+ QAL+ + +++ L EA + + E LA+RK + K
Sbjct: 641 ALQADY-QALQQRES------AIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKA 693
Query: 342 RI---EAILLQ--------MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGE 390
++ EAIL EEV + A A EL A ++ Q+ + E G+
Sbjct: 694 QMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAEKGQ 753
Query: 391 ---------KADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLE---DGSPRRSQEL 438
+A EL Q+ +AQL +G ++R Q + + L + + D + +L
Sbjct: 754 QGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQL 813
Query: 439 SLPQ 442
S+ +
Sbjct: 814 SMAE 817
Score = 32.0 bits (71), Expect = 1.3
Identities = 76/370 (20%), Positives = 142/370 (38%), Gaps = 72/370 (19%)
Query: 144 IKELRVKDSLLRKHQERVQRLKEECEAG----SRELKRCKEENYDLAMRLAHQSEEKGAA 199
+ +L V++ LR+ +++ R +E A +L+ +E R A + +
Sbjct: 239 LDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERG-----RTAAEDNVRLTC 293
Query: 200 LMRNRDLQLEIDQLKHSLMKAEDDC----------KVERKHTLKLRHAMEQRPSQELLWE 249
L+ Q E+ Q + +K C K E HT R +P L E
Sbjct: 294 LVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQP---LAQE 350
Query: 250 LQQEKALLQARVQELEA-----SVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSL 304
L+ + L + Q L + ++ + K D +S E A ++ QE + +L
Sbjct: 351 LEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQAL 410
Query: 305 RKDLRQGEA--RRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAI----ERD 358
++ + E R+ E+ + ELQ L++D++ +R+ + ++E E D
Sbjct: 411 ERERTKVEEVNRQQSAQLEQLVKELQ---LKEDARASLERLVKEMAPLQEELSGKGQEAD 467
Query: 359 QAIATREELHA--------------QHARGLQEKDALRKQVRELGEKADELQLQVFQCEA 404
Q +EL A + + +EK+ L ++VR L + L+ Q+ Q
Sbjct: 468 QLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQ 527
Query: 405 QLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQP 464
+ SDLE+ + ++L +D Q+ LAG P+ P
Sbjct: 528 HV------------------SDLEE----QKKQLIQDKDHLSQQVGMLERLAGPPGPELP 565
Query: 465 FAALHQEQVL 474
A E ++
Sbjct: 566 VAGEKNEALV 575
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 65.5 bits (158), Expect = 1e-10
Identities = 79/364 (21%), Positives = 161/364 (44%), Gaps = 34/364 (9%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEE---CEAG 171
++ E + QK++ ++ +S +DD I+ELR K ++L+ + ++ + +L+ + C A
Sbjct: 86 MIQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTAT 145
Query: 172 SRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHT 231
R EE D+ L H E+K + + + Q + L+ L + + K
Sbjct: 146 HRYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDM 205
Query: 232 LKLR---HAMEQRPSQELLWELQQEKALLQARVQELEASVQE-GKLD-RSSPYIQVLEED 286
+KL H + + S + ++ +LQ R+QEL+ E KL + ++Q +E
Sbjct: 206 MKLELDLHGLREETSAH-IERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEM 264
Query: 287 WRQALRDHQEQANTIFSLRKDLRQGEA------RRLRCMEEKEMFELQCLALRKDSKMYK 340
++ + + N++ K+L + + ++ ++ + E +C AL+ + + K
Sbjct: 265 LQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLK 324
Query: 341 DRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQ---- 396
+ +E Q E +A ++ L H Q K L+K + +KAD +Q
Sbjct: 325 NSLEE-AKQQERLAAQQAAQCKEEAALAGCHLEDTQRK--LQKGLLLDKQKADTIQELQR 381
Query: 397 -LQVFQCEAQLLAVEGRLRRQQLETLVL-------SSDLEDGSPRRSQELSLPQDLEDTQ 448
LQ+ Q E+ + E R+++E L L + D R+ Q+ QD++
Sbjct: 382 ELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMND 441
Query: 449 LSDK 452
+ D+
Sbjct: 442 MLDR 445
Score = 35.0 bits (79), Expect = 0.16
Identities = 62/300 (20%), Positives = 123/300 (41%), Gaps = 40/300 (13%)
Query: 127 QKKVQDLTALLSSKDDFIKELRVK-DSLLRKHQERVQRL--KEECEAGSRELKRCKEENY 183
Q+ +QDL ++ + + + L+ + D L+K + +Q KE +A SR+ C+++
Sbjct: 542 QQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLT 601
Query: 184 DLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLR-------- 235
+L H + E + Q + QL+ ++ E+ K KLR
Sbjct: 602 QALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESEL 661
Query: 236 --HA----MEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQ 289
HA +E+ Q L W+ Q + L + E ++E + + ++ +LE+D
Sbjct: 662 EVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAK--EEQLREFQEEMAALKENLLEDDKEP 719
Query: 290 ALRDHQEQANTIFSLRKD---LRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAI 346
+S+ KD L +G + + +E + + Q +A K +++++ I
Sbjct: 720 CCLPQ-------WSVPKDTCRLYRGNDQIMTNLE--QWAKQQKVANEKLGNQLREQVKYI 770
Query: 347 LLQMEEVAIERDQAIA---------TREELHAQHARGLQEKDALRKQVRELGEKADELQL 397
E E +A + + LH+ QE L+K++ E KA+ +L
Sbjct: 771 AKLSGEKDREPTRASSPNTTRPSSPSHSHLHSVMVHLQQENKKLKKEIEEKKMKAENTRL 830
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 65.5 bits (158), Expect = 1e-10
Identities = 79/364 (21%), Positives = 161/364 (44%), Gaps = 34/364 (9%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEE---CEAG 171
++ E + QK++ ++ +S +DD I+ELR K ++L+ + ++ + +L+ + C A
Sbjct: 231 MIQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTAT 290
Query: 172 SRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHT 231
R EE D+ L H E+K + + + Q + L+ L + + K
Sbjct: 291 HRYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDM 350
Query: 232 LKLR---HAMEQRPSQELLWELQQEKALLQARVQELEASVQE-GKLD-RSSPYIQVLEED 286
+KL H + + S + ++ +LQ R+QEL+ E KL + ++Q +E
Sbjct: 351 MKLELDLHGLREETSAH-IERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEM 409
Query: 287 WRQALRDHQEQANTIFSLRKDLRQGEA------RRLRCMEEKEMFELQCLALRKDSKMYK 340
++ + + N++ K+L + + ++ ++ + E +C AL+ + + K
Sbjct: 410 LQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLK 469
Query: 341 DRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQ---- 396
+ +E Q E +A ++ L H Q K L+K + +KAD +Q
Sbjct: 470 NSLEE-AKQQERLAAQQAAQCKEEAALAGCHLEDTQRK--LQKGLLLDKQKADTIQELQR 526
Query: 397 -LQVFQCEAQLLAVEGRLRRQQLETLVL-------SSDLEDGSPRRSQELSLPQDLEDTQ 448
LQ+ Q E+ + E R+++E L L + D R+ Q+ QD++
Sbjct: 527 ELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMND 586
Query: 449 LSDK 452
+ D+
Sbjct: 587 MLDR 590
Score = 37.0 bits (84), Expect = 0.041
Identities = 54/284 (19%), Positives = 120/284 (42%), Gaps = 28/284 (9%)
Query: 127 QKKVQDLTALLSSKDDFIKELRVK-DSLLRKHQERVQRL--KEECEAGSRELKRCKEENY 183
Q+ +QDL ++ + + + L+ + D L+K + +Q KE +A SR+ C+++
Sbjct: 687 QQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLT 746
Query: 184 DLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQRPS 243
+L H + E + LQ + Q + + E++ + KL E R
Sbjct: 747 QALEKLNHVTSE-------TKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLN--TELRKL 797
Query: 244 QELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFS 303
+ E + E +++E+ V + + + + ++ + LR+ QE+ + +
Sbjct: 798 RGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKE--EQLREFQEE---MAA 852
Query: 304 LRKDLRQGEARRLRCMEEKEMFELQCLALRKD----------SKMYKDRIEAILLQMEEV 353
L+++L + + + C+ + + + C R + +K K E + Q+ E
Sbjct: 853 LKENLLEDD-KEPCCLPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQ 911
Query: 354 AIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQL 397
+ ++ LH+ QE L+K++ E KA+ +L
Sbjct: 912 VKYIAKLSGEKDHLHSVMVHLQQENKKLKKEIEEKKMKAENTRL 955
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 65.5 bits (158), Expect = 1e-10
Identities = 81/373 (21%), Positives = 170/373 (45%), Gaps = 42/373 (11%)
Query: 114 GLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKEL-----RVKDSLLRKHQERVQR----- 163
G ++ L V +LQ++++DL + + +K+ +++++L+ +E +
Sbjct: 836 GRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARR 895
Query: 164 -LKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAE- 221
L+ E EA L + +E L+ +L +SE+K +++ E L ++ K +
Sbjct: 896 ALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQK 955
Query: 222 ---DDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLD--RS 276
D + R TL+L++ +++ + ++E A +Q +++E ++ +L +
Sbjct: 956 EMADIVEASRTSTLELQNQLDEYKEKN-----RRELAEMQRQLKEKTLEAEKSRLTAMKM 1010
Query: 277 SPYIQVLEEDWR-------QALRDHQEQANTIFSL------RKDLRQGEARRLRCMEEK- 322
++++EE+ R +AL Q T+ L + L+ +R ++ ME+K
Sbjct: 1011 QDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKV 1070
Query: 323 EMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQH-ARGLQEKDAL 381
E++ R +S + +RI QME++ E Q A R++L + Q KD
Sbjct: 1071 SQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLK 1130
Query: 382 RKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLE--TLVLSSDLEDGSPRRSQELS 439
+ + G + V Q EA++ +E RL ++ + L LS+ + R+ +EL
Sbjct: 1131 SRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLE---RKVKELV 1187
Query: 440 LPQDLEDTQLSDK 452
+ D E L+D+
Sbjct: 1188 MQVDDEHLSLTDQ 1200
Score = 48.9 bits (115), Expect = 1e-05
Identities = 70/340 (20%), Positives = 138/340 (40%), Gaps = 28/340 (8%)
Query: 129 KVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMR 188
+V+DL S + EL+ + L K+Q+ ++ +E A EL+ E +
Sbjct: 608 EVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENST 667
Query: 189 LAHQSEEKGAALMRNRD--LQLEIDQLKHSL-MKAEDDCKVERKHTLKLRHAMEQRPSQE 245
L + EE L +N + Q+++++ +H ++ D E L E R
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGA 727
Query: 246 LLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLR 305
L+ EL Q K LQ + + QE L + + L+ ++ + H ++ + +
Sbjct: 728 LIEELLQAKQDLQDLL--IAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKL---- 781
Query: 306 KDLRQGEARRLRCMEEKEMFELQCLALRKDS------------KMYKDRIEAILLQMEEV 353
K+ E + LR E+ ++ LA R ++ K+ ++ E + + EE+
Sbjct: 782 KEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEEL 841
Query: 354 AIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQC-------EAQL 406
Q E+L A+ + ++R+L E + + + E +L
Sbjct: 842 ERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENEL 901
Query: 407 LAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLED 446
A +G L + E LS L++ S ++ Q L ++E+
Sbjct: 902 EAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMEN 941
Score = 36.6 bits (83), Expect = 0.053
Identities = 47/213 (22%), Positives = 94/213 (44%), Gaps = 30/213 (14%)
Query: 113 SGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKH--QERVQRLKEECEA 170
S L + + +V +L+ ++++ + I R + LR QER R EC+
Sbjct: 1060 SRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDK 1119
Query: 171 GSRELKRCKEENYDLAMRLAH-----QSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCK 225
S E +N DL R+ H +S ++G + ++ I +L+ L E D
Sbjct: 1120 ISLE-----RQNKDLKSRIIHLEGSYRSSKEGLVVQ----MEARIAELEDRLESEERD-- 1168
Query: 226 VERKHTLKLRHAMEQRPSQELLWELQQE-------KALLQARVQELEASVQEGK--LDRS 276
+ L+L + +R +EL+ ++ E K L R++ ++ V+E + +DR
Sbjct: 1169 ---RANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRL 1225
Query: 277 SPYIQVLEEDWRQALRDHQEQANTIFSLRKDLR 309
+ L+ + + + ++ + S++KDLR
Sbjct: 1226 ESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLR 1258
Score = 32.3 bits (72), Expect = 1.0
Identities = 32/138 (23%), Positives = 64/138 (46%), Gaps = 23/138 (16%)
Query: 319 MEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEK 378
+E+K ++ L++ +++ + + + ER++ A EEL +QH ++E
Sbjct: 613 LEQKSKLTIEVAELQR-------QLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEEN 665
Query: 379 DALRKQVREL-GEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQE 437
L++++ E GE L+ ++FQ ++ R+Q +T + DL+D E
Sbjct: 666 STLQQRLEESEGELRKNLE-ELFQV---------KMEREQHQTEI--RDLQDQLSEMHDE 713
Query: 438 LSLPQDLEDTQLSDKGCL 455
L + ED +KG L
Sbjct: 714 LDSAKRSED---REKGAL 728
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 65.1 bits (157), Expect = 1e-10
Identities = 69/303 (22%), Positives = 135/303 (44%), Gaps = 54/303 (17%)
Query: 122 EVMKLQKKVQDLTALL----SSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKR 177
++ KLQ +++D L +S+++ + + + + L+ + + +L+EE A R ++
Sbjct: 1639 QLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQ 1698
Query: 178 CKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAED--------------- 222
++E +LA +A+ S + AL R L+ I QL+ L + +
Sbjct: 1699 AQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQ 1758
Query: 223 ------DCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRS 276
D +ER H K +A +Q L+++ L+ ++QE+E +V+ +
Sbjct: 1759 IDQINTDLNLERSHAQKNENARQQ---------LERQNKELKVKLQEMEGTVKS----KY 1805
Query: 277 SPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEK-EMFELQCLALRKD 335
I LE Q +EQ + RQ +++R E+K + LQ R++
Sbjct: 1806 KASITALEAKIAQL----EEQLDN----ETKERQAACKQVRRTEKKLKDVLLQVDDERRN 1857
Query: 336 SKMYKD-------RIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVREL 388
++ YKD R++ + Q+EE E +A A+R +L + + DA+ ++V L
Sbjct: 1858 AEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSL 1917
Query: 389 GEK 391
K
Sbjct: 1918 KNK 1920
Score = 61.2 bits (147), Expect = 2e-09
Identities = 74/332 (22%), Positives = 147/332 (44%), Gaps = 44/332 (13%)
Query: 115 LTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEECEA 170
L LM E ++LQ+++Q T L + ++ L K + + + RV+ +E C+
Sbjct: 874 LQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQH 933
Query: 171 GSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKH 230
E K+ ++ +L +L EE+ A + LQLE + L K E+
Sbjct: 934 LQAEKKKMQQNIQELEEQL---EEEESA----RQKLQLEKVTTEAKLKKLEE-------- 978
Query: 231 TLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGK-----LDRSSPYIQVLEE 285
EQ ++ +L +EK LL+ R+ E ++ E + L + + +
Sbjct: 979 --------EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030
Query: 286 DWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEA 345
D + LR ++Q + R+ L +G++ L ++ + Q L+ ++ ++A
Sbjct: 1031 DLEERLRREEKQRQELEKTRRKL-EGDSTDL--SDQIAELQAQIAELKMQLAKKEEELQA 1087
Query: 346 ILLQMEEVAIERDQAIATREELHAQHARGLQE--------KDALRKQVRELGEKADELQL 397
L ++EE A +++ A+ EL +Q + LQE ++ KQ R+LGE+ + L+
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELESQISE-LQEDLESERASRNKAEKQKRDLGEELEALKT 1146
Query: 398 QVFQCEAQLLAVEGRLRRQQLETLVLSSDLED 429
++ A + +++ E +L LE+
Sbjct: 1147 ELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Score = 60.8 bits (146), Expect = 3e-09
Identities = 69/305 (22%), Positives = 133/305 (43%), Gaps = 41/305 (13%)
Query: 160 RVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMK 219
+V R +EE A EL + +E+ RL + + LQ ++ +
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 220 AED---DCKVERKHTLKLRHAMEQR--PSQELLWELQQEKALLQARVQELEASVQEGKLD 274
AE+ +++ ++ H +E R +E LQ EK +Q +QELE ++E
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE---- 954
Query: 275 RSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRK 334
EE RQ L+ E+ T EA+ + EE+ + E Q L K
Sbjct: 955 ---------EESARQKLQ--LEKVTT-----------EAKLKKLEEEQIILEDQNCKLAK 992
Query: 335 DSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQE--------KDALRKQVR 386
+ K+ +DRI + E E+ +++A + H L+E + L K R
Sbjct: 993 EKKLLEDRIAEFTTNLTEEE-EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR 1051
Query: 387 ELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLED 446
+L + +L Q+ + +AQ+ ++ +L +++ E + +E+ + +++ L ++LE
Sbjct: 1052 KLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE- 1110
Query: 447 TQLSD 451
+Q+S+
Sbjct: 1111 SQISE 1115
Score = 57.0 bits (136), Expect = 4e-08
Identities = 77/322 (23%), Positives = 141/322 (43%), Gaps = 30/322 (9%)
Query: 145 KELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE---NYDLAMRLAHQSEEKGAALM 201
+E K L + E K E E +++ + E+ + D + H+ E+ AL
Sbjct: 1472 REKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALE 1531
Query: 202 RN-RDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQAR 260
+ +++ ++++L+ L +A +D K+ + L+ A +R Q + +++K L +
Sbjct: 1532 QQVEEMKTQLEELEDEL-QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 261 VQELEASVQEGKLDRSSPYI--QVLEEDWRQALRDHQEQAN-TIFSLRKDLRQGEARRLR 317
V+E+EA +++ + RS + LE D + L H + AN K LR+ +A+
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKD-LEAHIDSANKNRDEAIKQLRKLQAQMKD 1649
Query: 318 CMEEKE-----MFELQCLALRKDSKMYKDRIEAILLQMEEVAIERD--QAIATREEL--- 367
CM E + E+ A + K+ E I LQ E A ER QA R+EL
Sbjct: 1650 CMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE 1709
Query: 368 ----HAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVL 423
+ A L+EK L ++ +L E+ +E Q + RL++ L+ +
Sbjct: 1710 IANSSGKGALALEEKRRLEARIAQLEEELEEEQ-------GNTELINDRLKKANLQIDQI 1762
Query: 424 SSDLEDGSPRRSQELSLPQDLE 445
++DL + + Q LE
Sbjct: 1763 NTDLNLERSHAQKNENARQQLE 1784
Score = 56.6 bits (135), Expect = 5e-08
Identities = 73/334 (21%), Positives = 134/334 (40%), Gaps = 35/334 (10%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEECEAGSRELKRCKE 180
+LQ+++ DL L + L K D LL + + + EE + E + +
Sbjct: 1417 RLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKET 1476
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
+ LA L E+K N+ + E++ L M ++DD K + A+EQ
Sbjct: 1477 KALSLARALEEAMEQKAELERLNKQFRTEMEDL----MSSKDDVGKSVHELEKSKRALEQ 1532
Query: 241 RPSQ------ELLWELQ---QEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQAL 291
+ + EL ELQ K L+ +Q ++A + R + EE +Q +
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRD----EQSEEKKKQLV 1588
Query: 292 RDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQME 351
R +E + RK A R + + + E + K+ ++ + QM+
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 352 EVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEG 411
+ E D A+REE+ A Q +E +K ++ ++ Q + +L A E
Sbjct: 1649 DCMRELDDTRASREEILA--------------QAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 412 RLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
R+ Q E L+ ++ + S + + L + LE
Sbjct: 1695 AKRQAQQERDELADEIANSSGKGALALEEKRRLE 1728
Score = 52.0 bits (123), Expect = 1e-06
Identities = 71/355 (20%), Positives = 154/355 (43%), Gaps = 37/355 (10%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDD----FIKELRVKDSLLRKHQERVQRLKEECEAGSRE 174
L +V KLQ ++ ++T LLS D K+ +S L+ QE +Q + + S +
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 175 LKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKL 234
LK+ ++E +L + E K + L ++ +K + + + + KL
Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL 1390
Query: 235 RHAME---QRPSQELLW--ELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQ 289
+ +E QR +++ +L++ K LQ + +L + + +S+ ++ ++ + Q
Sbjct: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQR--QSACNLEKKQKKFDQ 1448
Query: 290 ALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQ 349
L + ++ + ++ +D + EAR EKE L +++ K +E + Q
Sbjct: 1449 LLAE-EKTISAKYAEERDRAEAEAR------EKETKALSLARALEEAMEQKAELERLNKQ 1501
Query: 350 ----MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQ 405
ME++ +D + EL Q+ + ++ Q+ EL ++ + + E
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 406 LLAVEGRLRR----------QQLETLV-----LSSDLEDGSPRRSQELSLPQDLE 445
L A++ + R ++ + LV + ++LED +RS ++ + LE
Sbjct: 1562 LQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLE 1616
Score = 48.5 bits (114), Expect = 1e-05
Identities = 74/360 (20%), Positives = 153/360 (42%), Gaps = 48/360 (13%)
Query: 121 TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELK---- 176
T + + ++K + L L + + I +L + K ++ +++ + + E S +L
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 177 RCKEENYDLAMRLAHQSEE--------------KGAALMRNRDLQLEIDQLKHSLMKAED 222
+ + +L M+LA + EE K AL + R+L+ +I +L+ L
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 223 DCKVERKHTLKLRHAME------------QRPSQELLWELQQEKALLQARVQELEASVQE 270
K L +E QEL + +QE +L+ ++E EA E
Sbjct: 1126 SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE-EAKTHE 1184
Query: 271 GKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMF-ELQC 329
+ IQ + + QA+ + EQ ++ +L +A++ E E+ E++
Sbjct: 1185 AQ-------IQEMRQKHSQAVEELAEQLEQTKRVKANLE--KAKQTLENERGELANEVKV 1235
Query: 330 LALRK-DSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVREL 388
L K DS+ + ++EA Q++E+ ++ ++ R EL + + E D + + +
Sbjct: 1236 LLQGKGDSEHKRKKVEA---QLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQS 1292
Query: 389 GEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQ 448
K+ +L E+QL + L+ + + L LS+ L+ ++ S + LE+ +
Sbjct: 1293 DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN---SFREQLEEEE 1349
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 64.7 bits (156), Expect = 2e-10
Identities = 85/363 (23%), Positives = 160/363 (44%), Gaps = 53/363 (14%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRC 178
L + + + K +L + + +D + E R K+ +++ + K + + EL R
Sbjct: 1232 LSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQ 1291
Query: 179 KEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQ-------LKHSLMKAEDDCKV----- 226
EE + +L S K A + +L+ ++++ L H+L + DC +
Sbjct: 1292 LEEKESIVSQL---SRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQY 1348
Query: 227 --ERKHTLKLRHAMEQRPSQELLW-------------ELQQEKALLQARVQELEASVQE- 270
E++ +L+ A+ + S+ W EL++ K L R+Q+ E V+
Sbjct: 1349 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAV 1408
Query: 271 ----GKLDRSSPYIQVLEEDWRQALRDHQEQANTIFS-LRKDLRQGEAR----RLRCMEE 321
L+++ +Q ED L E+AN++ + L K R + + +C E
Sbjct: 1409 NAKCASLEKTKQRLQGEVED----LMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEES 1464
Query: 322 KEMFEL---QCLALRKDSKMYKDRIEAILLQMEEVAIER---DQAIATREELHAQHARGL 375
+ E + +L + K+ E L Q+E V E +Q IA E A++ + +
Sbjct: 1465 QAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTI 1524
Query: 376 QEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRS 435
E + RKQ+ EL EKAD +QL + + EA L E ++ R QLE + S+++ +
Sbjct: 1525 HELEKSRKQI-EL-EKAD-IQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKD 1581
Query: 436 QEL 438
+E+
Sbjct: 1582 EEI 1584
Score = 53.1 bits (126), Expect = 6e-07
Identities = 70/344 (20%), Positives = 147/344 (42%), Gaps = 67/344 (19%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRC 178
L+ +L+ K++++T +++ EL K RK ++ LK++ +
Sbjct: 909 LIKAKFQLEAKIKEVTERAEDEEEINAELTAKK---RKLEDECSELKKDID--------- 956
Query: 179 KEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCK-VERKHTLKLRHA 237
DL + LA +EK A + ++L E+ L ++ K + K ++ H L
Sbjct: 957 -----DLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD-- 1009
Query: 238 MEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQ 297
+ + ++ + L + K+ L+ +V++LE+S+++ K R LE + R+ D +
Sbjct: 1010 -DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVD-----LERNKRKLEGDLKLA 1063
Query: 298 ANTIFSLRKDLRQGEARRLR-----CMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEE 352
+I L D +Q + R + C + ++ + Q L L+ ++ +I+ + ++EE
Sbjct: 1064 QESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQ-----FQKKIKELQARIEE 1118
Query: 353 VAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGR 412
+ E + ATR + Q + +E + L +++ E G
Sbjct: 1119 LEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGG---------------------- 1156
Query: 413 LRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLA 456
V S+ +E R ++ L L +DLE+ L + +A
Sbjct: 1157 ---------VTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVA 1191
Score = 53.1 bits (126), Expect = 6e-07
Identities = 83/347 (23%), Positives = 146/347 (42%), Gaps = 52/347 (14%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
E +LQ KV+D L IKEL Q R++ L+EE EA + +++
Sbjct: 1087 EYCQLQSKVEDEQTLGLQFQKKIKEL----------QARIEELEEEIEAERATRAKTEKQ 1136
Query: 182 NYDLAMRLAHQSEEKGAA---------LMRNRDLQ-------LEIDQLKHSLMKAEDDCK 225
D A L SE A L + R+ + LE L+H M A
Sbjct: 1137 RSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVA----A 1192
Query: 226 VERKHTLKLRHAMEQRPS-QELLWELQQEKALLQARVQELEASVQEGKLDRSS--PYIQV 282
+ +KH + EQ + Q + +L++EK+ + + +L +S++ +++ +
Sbjct: 1193 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRT 1252
Query: 283 LEEDWRQALRDHQEQANTIFSL--RKDLRQGEARRL-RCMEEKEMFELQCLALRKDSKMY 339
LE+ +A ++E ++ L +K Q EA L R +EEKE Q L + + +
Sbjct: 1253 LEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQ---LSRSKQAF 1309
Query: 340 KDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQV 399
+ E + Q+EE E A L + + D LR+Q E E ELQ +
Sbjct: 1310 TQQTEELKRQLEE---ENKAKNALAHALQSSR----HDCDLLREQYEEEQEGKAELQRAL 1362
Query: 400 FQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLED 446
+ ++ V + + + + + +LE+ + +Q L QD E+
Sbjct: 1363 SKANSE---VAQWRTKYETDAIQRTEELEEAKKKLAQRL---QDSEE 1403
Score = 41.2 bits (95), Expect = 0.002
Identities = 64/322 (19%), Positives = 135/322 (41%), Gaps = 57/322 (17%)
Query: 124 MKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSREL-------K 176
++L + ++ ++ KD+ I++L+ R +Q V+ ++ +A R K
Sbjct: 1564 LELTQVKSEIDRKIAEKDEEIEQLK------RNYQRTVETMQSALDAEVRSRNEAIRLKK 1617
Query: 177 RCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRH 236
+ + + ++ ++L+H + + L R +Q QLK + + +D +
Sbjct: 1618 KMEGDLNEIEIQLSHANRQAAETLKHLRSVQ---GQLKDTQLHLDDALR----------- 1663
Query: 237 AMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQE 296
Q +E L +++ LLQA V+EL A++++ + R ++L+ + R L H +
Sbjct: 1664 --GQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLL-HTQ 1720
Query: 297 QANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIE 356
+ I + +K M+ + E R + K I + EE+ E
Sbjct: 1721 NTSLIHTKKK-------LETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKE 1773
Query: 357 RDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQ 416
+D + A + K L + V++L + DE + QL G+ + Q
Sbjct: 1774 QDTS-----------AHLERMKKNLEQTVKDLQHRLDEAE--------QLALKGGKKQIQ 1814
Query: 417 QLETLVLSSDLE-DGSPRRSQE 437
+LET + + E +G +++ E
Sbjct: 1815 KLETRIRELEFELEGEQKKNTE 1836
Score = 30.0 bits (66), Expect = 5.0
Identities = 33/150 (22%), Positives = 68/150 (45%), Gaps = 13/150 (8%)
Query: 305 RKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL---LQMEEVAIERDQAI 361
RK+L E + + ++EK +LQ A ++ ++R + ++ Q+E E +
Sbjct: 871 RKEL---EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERA 927
Query: 362 ATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETL 421
EE++A+ +K L + EL + D+L+L + + E + A E +++ E
Sbjct: 928 EDEEEINAELTA---KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEL- 983
Query: 422 VLSSDLEDGSPRRSQELSLPQDLEDTQLSD 451
S L++ + ++E Q+ L D
Sbjct: 984 ---SGLDETIAKLTREKKALQEAHQQALDD 1010
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 64.3 bits (155), Expect = 2e-10
Identities = 84/338 (24%), Positives = 149/338 (44%), Gaps = 31/338 (9%)
Query: 123 VMKLQKKVQDLTALLSSKDDFIKELRVKDSLL----RKHQERVQRLKEECEAGSRELKRC 178
V +L+ + +DL + L F EL S + +K ++ L +E +A S EL R
Sbjct: 153 VKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRN 212
Query: 179 KEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAM 238
+ +L + A E+ ++QL + +LK L +A+ L L
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK----------LLLPQQQ 262
Query: 239 EQRPSQELLWELQQEKALLQARVQELEA-----SVQEGKLDRSSPYIQVLEEDWRQALRD 293
Q + L ELQ A LQA+V+E E QE K+ R IQ EE ++
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 294 HQEQANTIFSLRKDLRQGE------ARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL 347
+EQ I + +R+ E ++R EE M+E + R++ M++ E +
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM-MWEKEEKMRRQEEMMWEK--EEKM 379
Query: 348 LQMEEVAIERDQAIATREE-LHAQH-ARGLQEKDALRKQVRELGEKADELQLQVFQCEAQ 405
+ EE+ E+++ I EE +H Q R +EK +++RE EK E + ++++ E +
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEK 438
Query: 406 LLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQD 443
+ E ++R Q+ + + + R +E Q+
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
Score = 62.0 bits (149), Expect = 1e-09
Identities = 67/367 (18%), Positives = 164/367 (44%), Gaps = 46/367 (12%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKE----LRVKDSLLRKHQERVQRLKEECEAGSRELKR 177
++ + ++K+Q+ + +++ I+E +R ++ ++ + +E+++R +E +++R
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
Query: 178 CKEENYDLAMRLAHQSEEKGAALMRNRDLQ----------------LEIDQLKHSLMKAE 221
+E ++ ++ Q E + R+L+ E ++++ + E
Sbjct: 368 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427
Query: 222 DDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQ 281
+ K+ R+ K+R E+ QE Q+EK Q +++E E ++ ++ R I
Sbjct: 428 QEAKMWRQEE-KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
Query: 282 VLEEDWRQALRDHQEQANTIFSLRKDLRQGE-----ARRLRCMEEK-----EMFELQCLA 331
EE WRQ + H+++ K RQ E ++R EEK E Q
Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546
Query: 332 LRKDSKMY-----------KDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDA 380
R++ KM+ +++ + + Q E++ + ++ E++ Q + ++++
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 381 LRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSL 440
+ KQ ++ E+ +++Q Q E ++ E ++R Q+ T + + + ++
Sbjct: 607 MWKQEEKIREQEEKIQEQ----EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662
Query: 441 PQDLEDT 447
Q+ E+T
Sbjct: 663 MQEQEET 669
Score = 30.4 bits (67), Expect = 3.8
Identities = 31/146 (21%), Positives = 69/146 (47%), Gaps = 18/146 (12%)
Query: 156 KHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEK-GAALMRNRDLQLEIDQLK 214
K +E+ ++++E+ E + ++ +E+ + + EEK G + + + ++ + +
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQE-----EMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 215 HSLMKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQAR---VQELEASVQEG 271
++ + E+ + + K K+R E+ QE + + Q+EK Q QE + QE
Sbjct: 668 ETMWRQEEKIREQEK---KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724
Query: 272 KLDRSSPYIQVLEEDWRQALRDHQEQ 297
K+ R E+ W Q +R Q++
Sbjct: 725 KMRRQE------EKMWEQEVRLRQQE 744
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 64.3 bits (155), Expect = 2e-10
Identities = 73/334 (21%), Positives = 145/334 (43%), Gaps = 55/334 (16%)
Query: 116 TQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSREL 175
+QL ++ +LQK++++ LL ++ D LR + + K +++ L E + +R L
Sbjct: 533 SQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRIL 592
Query: 176 KRCKEEN----YDLAMRL-------AHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDC 224
+ K + Y L L H SE G R LQ E+ LKH+L K E +
Sbjct: 593 ENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGER 652
Query: 225 K---------VERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDR 275
K + K+ L++ + + Q+ L + E + +AR+ + S++E K
Sbjct: 653 KEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAK--- 709
Query: 276 SSPYIQVLEEDWRQALRDHQEQANTIFSLRK-------DLRQGEARRLRCMEEKEMFELQ 328
S + +E+ ++ ++ N + + K DL+Q + + KE E
Sbjct: 710 -SVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERME-- 766
Query: 329 CLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATREEL-----HAQHARGLQEKDALRK 383
D ++ + LQ+E+ E ++ + + EL A + +GL+++ +++
Sbjct: 767 ------------DEVKNLTLQLEQ---ESNKRLLLQNELKTQAFEADNLKGLEKQ--MKQ 809
Query: 384 QVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQ 417
++ L E L+ ++ Q Q EG++R Q
Sbjct: 810 EINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQ 843
Score = 37.0 bits (84), Expect = 0.041
Identities = 64/321 (19%), Positives = 135/321 (42%), Gaps = 55/321 (17%)
Query: 83 LELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQD--------LT 134
LE QL K+ G E ++ + E + L T+V +L++++++ +
Sbjct: 821 LEFELAQLTKQYRGNE-GQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQ 879
Query: 135 ALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQ-S 193
L + K+ +L + ++ Q L+E+ ++E K+ N H S
Sbjct: 880 ELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVS 939
Query: 194 EEKGAALMRNRDLQL---EIDQLKHSLMKAEDDCKVERKHTL-KLRHAMEQRPSQELLWE 249
+ A M +D+++ E ++L + KAE++ K+E++ + L+ A E+ + E +
Sbjct: 940 RLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLK 999
Query: 250 LQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLR 309
Q L + + ++ K+DR ++ANT +DLR
Sbjct: 1000 TQAVNKLAEI------MNRKDFKIDR--------------------KKANT-----QDLR 1028
Query: 310 QGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHA 369
+ +EKE +LQ L L ++ + + + ++ ++ + + A R EL
Sbjct: 1029 K---------KEKENRKLQ-LELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQM 1078
Query: 370 QHARGLQEKDALRKQVRELGE 390
Q A + + LR ++ +L +
Sbjct: 1079 QLASKESDIEQLRAKLLDLSD 1099
Score = 32.7 bits (73), Expect = 0.77
Identities = 39/233 (16%), Positives = 101/233 (43%), Gaps = 51/233 (21%)
Query: 209 EIDQLKHSLMKAEDDCKVE-RKHTLKLRHAMEQ--------RPSQELLWELQQEKALLQA 259
++++ H+ M+ +D+ + + R +KL M++ R + + ++++EK LLQ
Sbjct: 434 KLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQH 493
Query: 260 RVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCM 319
R+ E + ++ R R+ + + +T+ +DL++
Sbjct: 494 RINEYQRKAEQENEKR----------------RNVENEVSTLKDQLEDLKK--------- 528
Query: 320 EEKEMFELQCLALRKDSKMYKDRIEAILLQMEE----VAIERDQAIATREELHAQHARGL 375
+ ++S++ +++ + Q+EE + E D A+ R+ H + ++ +
Sbjct: 529 ------------VSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKS-HTEMSKSI 575
Query: 376 QEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLE 428
+ ++L ++++E + + Q + QL A+ RR + + DL+
Sbjct: 576 SQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQ 628
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 64.3 bits (155), Expect = 2e-10
Identities = 67/301 (22%), Positives = 140/301 (46%), Gaps = 25/301 (8%)
Query: 155 RKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLK 214
+K ++ L +E +A S EL R N +L + A E+ A ++QL + +LK
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 215 HSLMKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASV--QEGK 272
L +A+ + +TL QE +W ++E + ++++ E + QE +
Sbjct: 215 RKLERAKFLLPQVQTNTL-----------QEEMWRQEEELREQEKKIRKQEEKMWRQEER 263
Query: 273 LDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCME------EKEMFE 326
L ++ EE R+ + +EQ + K+LR E ++LR E E++M+E
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR--EQKKLREQEEQMQEQEEKMWE 321
Query: 327 LQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVR 386
+ ++ KM+ R E L + E+ E++Q + +EE + L+EK+ ++
Sbjct: 322 QEEKMREQEEKMW--RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 387 ELGEKADELQLQ--VFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDL 444
++ E+ +++Q + + + E ++ E +R Q+ + ++ + + Q+ LP+
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 439
Query: 445 E 445
E
Sbjct: 440 E 440
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/361 (19%), Positives = 165/361 (45%), Gaps = 37/361 (10%)
Query: 82 SLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKD 141
SLELY + + K+ A + + A E QL V +L++K++ LL
Sbjct: 172 SLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQL---NVKELKRKLERAKFLLPQVQ 228
Query: 142 DFI---------KELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQ 192
+ELR ++ +RK +E++ R +E +++ +E+ RL Q
Sbjct: 229 TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQ 288
Query: 193 SEEKGAALMRNRDLQL-EIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR-PSQELLWEL 250
+E +R ++ +L E +L+ + ++ + + K+R E+ +E LWE
Sbjct: 289 EKE-----LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343
Query: 251 QQEKALLQARVQELEASV--QEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDL 308
+++ + ++++ E + Q+ +L ++ E+ W Q + ++ I K +
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ--EEKMQEEERIREREKKM 401
Query: 309 RQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI---------EAILLQMEEVAIERDQ 359
R+ E +R EEK + + + +++ + + R+ + + + EE E+++
Sbjct: 402 RE-EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 360 AIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQ---VFQCEAQLLAVEGRLRRQ 416
I +EE+ Q + + ++ +R+Q ++ E+ ++++ Q ++ E ++ + RLR +
Sbjct: 461 KIRDQEEMWGQEKK-MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 417 Q 417
+
Sbjct: 520 E 520
Score = 48.9 bits (115), Expect = 1e-05
Identities = 60/319 (18%), Positives = 152/319 (47%), Gaps = 33/319 (10%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERV----------QRLKEECEA- 170
E M+ ++++++ + +++ ++E K ++K +E + QRL E+ E
Sbjct: 386 EKMQEEERIREREKKMREEEETMREQEEK---MQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 171 -GSRELKRCKEENYDLAMRLAHQSEEKGAA--LMRNRDLQLEIDQL--KHSLMKAEDDCK 225
+++ +E+ ++ ++ Q E G + R ++ + DQ+ + M+ ++
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 226 VERKHTL-----KLRHAMEQRPSQELLWELQQEKALLQARVQELEASV--QEGKLDRSSP 278
+++ + +LR E+ Q+ +W+ Q+EK + + QE E QE K+ R
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQ-QEEKMREEKKTQEQEKKTWDQEEKM-REEE 560
Query: 279 YIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKM 338
++ E+ R+ +EQ + + +R+ E + +E++M E + ++ KM
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE--QEEKMQEQEEKMWEQEEKM 618
Query: 339 YKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQ 398
++ E + + EE+ E+++ + +EE + ++E++ +++RE EK + +
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE---EKMREQEEKMQGQEEK 675
Query: 399 VFQCEAQLLAVEGRLRRQQ 417
+ + E ++ E ++R Q+
Sbjct: 676 MREQEEKMQGQEEKMREQE 694
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 64.3 bits (155), Expect = 2e-10
Identities = 81/337 (24%), Positives = 152/337 (45%), Gaps = 63/337 (18%)
Query: 127 QKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERV-------QRLKEECEAGSRELKRCK 179
QK + L + K+ + ++ KD L+ QE V Q+++EE ++ + +
Sbjct: 1857 QKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1916
Query: 180 EENYDLAMRLAHQSEEKGAAL-----------MRNRDLQLEIDQLKHSLMKAEDD----- 223
EE DL RL +Q E ++ ++N L+ E+ LK + + E++
Sbjct: 1917 EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLV 1976
Query: 224 ---CKVE---RKHTLKLRHAMEQRPS--------QELLWELQQEKALLQA-------RVQ 262
KVE RK L+ ++ P QELL E QQE LQ ++
Sbjct: 1977 KEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKIS 2036
Query: 263 ELEASVQ--EGKLDRSSPYIQVLEEDWRQALRDHQEQANT---IFSLRKDLRQGEARRLR 317
LE +V+ E S +++ +E+ QA+ +H+++A F + D Q EA R+
Sbjct: 2037 ALERTVKALEFVQTESQKDLEITKENLAQAV-EHRKKAQAELASFKVLLDDTQSEAARVL 2095
Query: 318 CMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQE 377
L L+K+ + K+ +++ + Q +E + ++ + EE H + + +QE
Sbjct: 2096 ADN---------LKLKKELQSNKESVKSQMKQKDE---DLERRLEQAEEKHLKEKKNMQE 2143
Query: 378 K-DALRKQVRELGEKADELQLQVFQCEAQLLAVEGRL 413
K DALR++ L E E+Q+ + + + ++ ++ L
Sbjct: 2144 KLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2180
Score = 60.8 bits (146), Expect = 3e-09
Identities = 78/340 (22%), Positives = 152/340 (44%), Gaps = 39/340 (11%)
Query: 121 TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKE 180
TEV +LQ+KV D L + + +L L Q + +L+ E LK K+
Sbjct: 2270 TEV-QLQQKVCD--TLQGENKELLSQLEETRHLYHSSQNELAKLESE-------LKSLKD 2319
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
+ DL+ L E+KG R + +I K S + E D + R+ T +L +
Sbjct: 2320 QLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2379
Query: 241 RPSQELLWELQQEKALLQARVQEL------EASVQEGKLDRSSPYIQVLEEDWRQALRDH 294
+ Q+++ L ++ +Q + EL E E L + VLEE+ ++A+
Sbjct: 2380 K-EQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2438
Query: 295 QEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEE-- 352
+ T+ +++K+ Q +A + + F +L+ D +DRI Q+EE
Sbjct: 2439 NQLMETLKTIKKENIQQKA-------QLDSFVKSMSSLQND----RDRIVGDYQQLEERH 2487
Query: 353 --VAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEA---QLL 407
+ +E+DQ I +E A++ + +E LR + +L + +L ++ Q Q++
Sbjct: 2488 LSIILEKDQLI---QEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2544
Query: 408 AVEGRLRRQQLET-LVLSSDLEDGSPRRSQELSLPQDLED 446
++ ++Q LE L + +LE+ + ++L ++ +
Sbjct: 2545 TIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANE 2584
Score = 55.1 bits (131), Expect = 1e-07
Identities = 77/331 (23%), Positives = 139/331 (41%), Gaps = 32/331 (9%)
Query: 119 LMTEVMKLQKKVQDLTA--------LLSSKDDFIKELRVKDS----LLRKHQERVQRLKE 166
L E+ L+ + DL + L+ ++D + + +KDS LL ++ + L+
Sbjct: 2508 LKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELEN 2567
Query: 167 ECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMK-AEDDCK 225
+ +LK +E N DL EEK +DL EI+ LK S+ +
Sbjct: 2568 KYAKLEEKLKESEEANEDLRRSFNALQEEK-------QDLSKEIESLKVSISQLTRQVTA 2620
Query: 226 VERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEE 285
++ + TL L HA + + +E + L + Q R+ ELE + + + + + +E+
Sbjct: 2621 LQEEGTLGLYHA-QLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKK-VGEIED 2678
Query: 286 DWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEA 345
++ L+ A +R + E R + E + L + K++K +I++
Sbjct: 2679 KLKKELKHLHHDAGI---MRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQS 2735
Query: 346 ILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQ---VRELGEKADELQLQVFQC 402
M + RD A +EL ++ L+E L++Q RE E +
Sbjct: 2736 FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNST 2795
Query: 403 EAQLLAVEGRLRRQQL----ETLVLSSDLED 429
E L+ +L +Q L + L LSS LED
Sbjct: 2796 EENSLSHLEKLNQQLLSKDEQLLHLSSQLED 2826
Score = 46.6 bits (109), Expect = 5e-05
Identities = 83/360 (23%), Positives = 148/360 (41%), Gaps = 55/360 (15%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRC 178
L E +LQKK+Q+ AL S K ++L+K QE+ + L+E ELK+
Sbjct: 1169 LEKEKEQLQKKLQE--ALTSRK-----------AILKKAQEKERHLRE-------ELKQQ 1208
Query: 179 KEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAED---DCKVERKHTLKLR 235
K++ L + QS+E + R LQ+++ + + + D C L
Sbjct: 1209 KDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLF 1268
Query: 236 HAMEQRPSQELL-------WELQQEK----------ALLQARVQELEASVQEGKLDRSSP 278
A EQ +Q +L W E A ++A+++E+EA E +L SS
Sbjct: 1269 KATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSST 1328
Query: 279 YIQVLE--EDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDS 336
++ + E+ Q +Q I SL+ + E ++ E +LQ L
Sbjct: 1329 TSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH-- 1386
Query: 337 KMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKD-ALRKQVRELGEKADEL 395
L +++ E + I+ +EE + + L EK+ AL K E+ E+ D +
Sbjct: 1387 ----------LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLI 1436
Query: 396 QLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCL 455
+ Q E Q + R+++ Q+E + E+ + + + L+ +S K L
Sbjct: 1437 KALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL 1496
Score = 43.1 bits (100), Expect = 6e-04
Identities = 74/371 (19%), Positives = 155/371 (41%), Gaps = 34/371 (9%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRC 178
L E+ ++++K +++ +K ++L+ ++ + + L+EE ++R
Sbjct: 1457 LQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERL 1516
Query: 179 KEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAM 238
+ D+ +++ Q++EK L R LQ E D+ L+ D +E
Sbjct: 1517 TKSLADVESQVSAQNKEKDTVLGRLALLQEERDK----LITEMDRSLLE----------- 1561
Query: 239 EQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQA 298
+Q L + K L+ ++ E V+E + +SS + E W++ ++ Q++
Sbjct: 1562 ----NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE--WQEKHKELQKEY 1615
Query: 299 NTIFSLRKDLRQGEARRLRCMEEKEMFELQCL-ALRKDSKMYKDRIEAILLQMEEVAIER 357
+ +++ EA R++ + E E Q L + ++ K E L + E+ E
Sbjct: 1616 EILLQSYENV-SNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEM 1674
Query: 358 DQAIATREELHAQHARGLQEK-DALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQ 416
+ + + Q L+E+ D LR +V G+ A E + A +++ L R
Sbjct: 1675 KEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNA---SMKEELERV 1731
Query: 417 QLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQPFAALHQEQVLRN 476
++E LS + S++ SL ++++D K + G S + A + N
Sbjct: 1732 KMEYETLSKKFQS---LMSEKDSLSEEVQDL----KHQIEGNVSKQANLEATEKHDNQTN 1784
Query: 477 PHDAGPAGLPG 487
+ G +PG
Sbjct: 1785 VTEEGTQSIPG 1795
Score = 42.0 bits (97), Expect = 0.001
Identities = 69/386 (17%), Positives = 160/386 (41%), Gaps = 47/386 (12%)
Query: 77 VAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTAL 136
++ + L QL + E R + ++ LT+ + + ++ + K + L
Sbjct: 756 LSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVL 815
Query: 137 LSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEK 196
+ DD + + +L+R Q ++Q + E G+ ++ + +L+ L+ +
Sbjct: 816 QNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQK---- 871
Query: 197 GAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQRPSQ---------ELL 247
+LEI ++ L++ + D + L+ +E++ Q E +
Sbjct: 872 ----------ELEITKMDQLLLEKKRDVET-------LQQTIEEKDQQVTEISFSMTEKM 914
Query: 248 WELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEE-DWRQALRDHQEQANTIFSLRK 306
+L +EK L ++ L+ + + QV E+ + L+ + ++ + + K
Sbjct: 915 VQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISK 974
Query: 307 DLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATREE 366
+ Q E L+ E+ +LQ + + K+ ++ + EE+A +D+ + +E
Sbjct: 975 EELQHEFDLLKKENEQRKRKLQAALINR-----KELLQRVSRLEEELANLKDE--SKKEI 1027
Query: 367 LHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSD 426
++ RG E+D K+ +E EK +C+ + ++ + +++E + D
Sbjct: 1028 PLSETERGEVEED---KENKEYSEKC-----VTSKCQEIEIYLKQTISEKEVELQHIRKD 1079
Query: 427 LEDGSPRRSQELSLPQDLEDTQLSDK 452
LE+ Q +L + + T L DK
Sbjct: 1080 LEEKLAAEEQFQALVKQMNQT-LQDK 1104
Score = 37.4 bits (85), Expect = 0.031
Identities = 56/283 (19%), Positives = 135/283 (47%), Gaps = 30/283 (10%)
Query: 123 VMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE- 181
V++L+ ++ L KD+ ++E R + ++++LK +A L + EE
Sbjct: 61 VVELKDIIRQKDVQLQQKDEALQEER------KAADNKIKKLKLHAKAKLTSLNKYIEEM 114
Query: 182 --NYDLAMRLAHQSEEKGAALMRNR-DLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAM 238
+ QSEE+ + ++ + ++EI+++KH L + E+ + +L A
Sbjct: 115 KAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQ---AQLTQAQ 171
Query: 239 EQRPSQEL--LWELQQEKALLQAR---VQELEASVQEGKLDRSSPYIQVLEEDWR--QAL 291
++P+Q + E K LQ + + L+A + + + ++++ + V E+D R +
Sbjct: 172 AEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQV-VREKDARFETQV 230
Query: 292 RDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQME 351
R H+++ + + + D+ ++LR ++ K L ++S + + ++ +L Q
Sbjct: 231 RLHEDELLQLVT-QADVETEMQQKLRVLQRK-------LEEHEESLVGRAQVVDLLQQEL 282
Query: 352 EVAIERDQAIATR-EELHAQHARGLQEKDALRKQVRELGEKAD 393
A +R+Q ++ + +++ A+H + R++ + L EK +
Sbjct: 283 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKME 325
Score = 37.4 bits (85), Expect = 0.031
Identities = 78/330 (23%), Positives = 135/330 (40%), Gaps = 60/330 (18%)
Query: 136 LLSSKDDFIKELRVKDSLLRKHQERVQRLKE---ECEAGSRELKRCKEENYDLA------ 186
L S+K D K L + + HQ+ ++RLK E E + + E+N D
Sbjct: 661 LKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISN 720
Query: 187 --------MRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAM 238
+ A + AL RD QL + Q+K M E +V++ + L A
Sbjct: 721 LNQLIEEFKKNADNNSSAFTALSEERD-QL-LSQVKELSMVTELRAQVKQLE-MNLAEAE 777
Query: 239 EQRPSQELLWELQ-QEKALLQARVQEL--EASVQEGKLDRSSPYIQVLEEDWRQALRDHQ 295
QR L +E Q LL ++ L EA ++ K I+VL+ +
Sbjct: 778 RQR---RLDYESQTAHDNLLTEQIHSLSIEAKSKDVK-------IEVLQNELDDVQLQFS 827
Query: 296 EQANTIFSLRKDLRQGE------ARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQ 349
EQ+ I SL+ L+ E A R+R + K Q L+ + E + +
Sbjct: 828 EQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQK----------ELEITK 877
Query: 350 MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAV 409
M+++ +E+ + + T ++ ++EKD +QV E+ E +Q+ + E L V
Sbjct: 878 MDQLLLEKKRDVETLQQT-------IEEKD---QQVTEISFSMTEKMVQLNE-EKFSLGV 926
Query: 410 EGRLRRQQLETLVLSSDLEDGSPRRSQELS 439
E + ++QL L + + + E+S
Sbjct: 927 EIKTLKEQLNLLSRAEEAKKEQVEEDNEVS 956
Score = 36.6 bits (83), Expect = 0.053
Identities = 74/353 (20%), Positives = 151/353 (42%), Gaps = 46/353 (13%)
Query: 121 TEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKE 180
T+V + ++ L + + ++LRV L +H+E + + + +EL ++
Sbjct: 228 TQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQ 287
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERK---HTL--KLR 235
N L+ +L E +RN ++ E ++ K L K E + ERK H L ++
Sbjct: 288 RNQILSQQLQQMEAEHNT--LRN-TVETEREESKILLEKMELEV-AERKLSFHNLQEEMH 343
Query: 236 HAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLE---EDWRQALR 292
H +EQ + Q +A L++R LE + +++ + +I L+ ++ + A
Sbjct: 344 HLLEQ------FEQAGQAQAELESRYSALEQK-HKAEMEEKTSHILSLQKTGQELQSACD 396
Query: 293 DHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEE 352
++Q + + + + A+ ++ +E++ L++ SK + + LQ E
Sbjct: 397 ALKDQNSKLLQDKNEQAVQSAQTIQQLEDQ---------LQQKSKEISQFLNRLPLQQHE 447
Query: 353 VAI---------ERDQAIATREELHAQHARGLQ---EKDALRKQVRELGEKADELQLQVF 400
A E QA+ T E + + R ++ EK AL EL +EL+ +
Sbjct: 448 TASQTSFPDVYNEGTQAV-TEENIASLQKRVVELENEKGALLLSSIEL----EELKAENE 502
Query: 401 QCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQEL-SLPQDLEDTQLSDK 452
+ +Q+ +E + R + + V + D + +RS QD+ + S K
Sbjct: 503 KLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQK 555
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 63.9 bits (154), Expect = 3e-10
Identities = 110/469 (23%), Positives = 206/469 (43%), Gaps = 64/469 (13%)
Query: 10 CWSVLEGFRVTLTSVIDPSRIT--PYLRQCKVLNPD-------DEEQVLS--------DP 52
C VLEG R+ P+RI + ++ ++L P+ D +Q DP
Sbjct: 701 CNGVLEGIRICRQGF--PNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDP 758
Query: 53 NLV-IRKRKV----GVLLDILQRTGHK--GYVAFLESLELYYPQLYKKVTGKEPARVFSM 105
NL I + K+ GVL + + K + F +++ Y L +K K+ ++ ++
Sbjct: 759 NLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGY--LARKAFAKKQQQLSAL 816
Query: 106 IIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLK 165
+ + +L + ++ KV+ L + ++ EL+ KD L K +E+ +++
Sbjct: 817 KVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEE----ELQAKDEELLKVKEKQTKVE 872
Query: 166 EECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCK 225
E E R+ ++ EE LA +L ++E L E ++++ L + + +
Sbjct: 873 GELEEMERKHQQLLEEKNILAEQLQAETE-----------LFAEAEEMRARLAAKKQELE 921
Query: 226 VERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEE 285
E H L+ R E+ +Q L Q EK +QA +Q+LE + E + R ++ +
Sbjct: 922 -EILHDLESRVEEEEERNQIL----QNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTA 976
Query: 286 DWRQALRDHQ----EQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKD 341
+ + + + E N+ F K L E R C + E + L K ++
Sbjct: 977 EAKIKKMEEEILLLEDQNSKFIKEKKLM--EDRIAECSSQLAEEEEKAKNLAK----IRN 1030
Query: 342 RIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQ 401
+ E ++ +EE + ++ TR+EL + E L+ Q+ EL + DEL+LQ+ +
Sbjct: 1031 KQEVMISDLEERLKKEEK---TRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAK 1087
Query: 402 CEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLS 450
E +L +G L R ETL ++ L+ ++Q L +D E + S
Sbjct: 1088 KEEEL---QGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
Score = 63.2 bits (152), Expect = 5e-10
Identities = 75/345 (21%), Positives = 158/345 (45%), Gaps = 38/345 (11%)
Query: 119 LMTEVMKLQKKVQD----LTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRE 174
++ ++ KLQ +++D L +S+D+ + + + L+ + + +L+EE + R
Sbjct: 1643 VIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERA 1702
Query: 175 LKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKV----ERKH 230
+ ++E +LA + + + K A L R L+ I QL+ L + + + ++ RK
Sbjct: 1703 RRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKT 1762
Query: 231 TLKL-----RHAMEQRPSQE---LLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQV 282
TL++ A E+ +Q+ +L+++ L+A++QELE +V+ + I
Sbjct: 1763 TLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVK----SKFKATISA 1818
Query: 283 LEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKD- 341
LE Q +++A + K +R+ E + KE+F +Q R+ + YK+
Sbjct: 1819 LEAKIGQLEEQLEQEAKERAAANKLVRRTEKKL------KEIF-MQVEDERRHADQYKEQ 1871
Query: 342 ------RIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELG---EKA 392
R++ + Q+EE E +A A+R +L + + + L ++V L +
Sbjct: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRG 1931
Query: 393 DELQLQVFQCEAQLLAVEG-RLRRQQLETLVLSSDLEDGSPRRSQ 436
+ + + L +EG L +T +SD+ + P +S+
Sbjct: 1932 GPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQSE 1976
Score = 56.6 bits (135), Expect = 5e-08
Identities = 69/333 (20%), Positives = 138/333 (41%), Gaps = 33/333 (9%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEECEAGSRELKRCKE 180
+LQ+++ DLT L + L K D LL + + R EE + E + +
Sbjct: 1424 RLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKET 1483
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
+ LA L E K +N+ L+ +++ L M ++DD K + A+EQ
Sbjct: 1484 KALSLARALEEALEAKEEFERQNKQLRADMEDL----MSSKDDVGKNVHELEKSKRALEQ 1539
Query: 241 RPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQ--- 297
++++ + L+ EL+A+ ++ KL R +Q ++ + + L+ EQ
Sbjct: 1540 --------QVEEMRTQLEELEDELQAT-EDAKL-RLEVNMQAMKAQFERDLQTRDEQNEE 1589
Query: 298 -----ANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEE 352
+ L +L +R + K+ E+ D K + +IEA +E
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKKKMEI-------DLKDLEAQIEAANKARDE 1642
Query: 353 VAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGR 412
V + + A ++ + +D + Q +E +K L+ ++ Q + +L + E
Sbjct: 1643 VIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERA 1702
Query: 413 LRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
R + E L+ ++ + + +S L + LE
Sbjct: 1703 RRHAEQERDELADEITNSASGKSALLDEKRRLE 1735
Score = 54.7 bits (130), Expect = 2e-07
Identities = 61/294 (20%), Positives = 140/294 (47%), Gaps = 23/294 (7%)
Query: 112 ESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEE 167
E Q+L E K+Q +QDL L ++ ++L+++ ++ ++K +E + L+++
Sbjct: 934 EEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQ 993
Query: 168 CEAGSRELKRCKEENYDLAMRLAHQSEE-KGAALMRNRDLQLEIDQLKHSLMKAEDDCKV 226
+E K ++ + + +LA + E+ K A +RN+ ++ I L+ L K E
Sbjct: 994 NSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQ-EVMISDLEERLKKEEK---- 1048
Query: 227 ERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEED 286
R+ K + ++ + +LQ + A LQA++ EL+ + + + + + +E
Sbjct: 1049 TRQELEKAKRKLDGETT-----DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDET 1103
Query: 287 WRQ--ALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIE 344
+ AL+ +E I L++D +A R + ++K + AL+ + +D ++
Sbjct: 1104 LHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE---LEDTLD 1160
Query: 345 AILLQMEEVAIERDQAIATREELHAQHARG--LQEKDALRKQVRELGEKADELQ 396
Q +E+ +R+Q +A ++ + + Q +D ++ L E +++L+
Sbjct: 1161 TTAAQ-QELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE 1213
Score = 51.2 bits (121), Expect = 2e-06
Identities = 96/420 (22%), Positives = 168/420 (40%), Gaps = 77/420 (18%)
Query: 89 QLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVM----KLQKKVQDLTALLSSKDDFI 144
Q+ + K A + + E G Q L E + K++K +++ L FI
Sbjct: 939 QILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFI 998
Query: 145 KELRVKD-------SLLRKHQERVQRL-----KEECEAGSRELKRCKEENYDLAMRLAHQ 192
KE ++ + S L + +E+ + L K+E E + KEE + A +
Sbjct: 999 KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058
Query: 193 SEEKGAALMRNR--DLQLEIDQLKHSLMKAE----------DDCKVERKHTLKLRHAMEQ 240
+ ++++ +LQ +ID+LK L K E DD + + + LK+ ++
Sbjct: 1059 KLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQA 1118
Query: 241 RPSQELLWELQQEKAL--------------LQARVQELE------ASVQEGKLDRSSPYI 280
+ + EL + + EKA L+A ELE A+ QE + R
Sbjct: 1119 QIA-ELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVA 1177
Query: 281 QVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEE--------KEMFELQCLAL 332
+ L++ + ++H+ Q +D+RQ A L + E K E L
Sbjct: 1178 E-LKKALEEETKNHEAQI-------QDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL 1229
Query: 333 RKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKA 392
D+K ++ + E +R + A +ELHA+ + E D LR EL EKA
Sbjct: 1230 ETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAK----VSEGDRLRV---ELAEKA 1282
Query: 393 DELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDK 452
+LQ ++ L E + + + L S L+D +QEL + + LS +
Sbjct: 1283 SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD-----TQELLQEETRQKLNLSSR 1337
Score = 51.2 bits (121), Expect = 2e-06
Identities = 67/289 (23%), Positives = 127/289 (43%), Gaps = 38/289 (13%)
Query: 131 QDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLA 190
++L AL + +D + + L K ++ V LK+ E E K + + D+ R A
Sbjct: 1146 EELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE---EETKNHEAQIQDMRQRHA 1202
Query: 191 HQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQRPSQELLWEL 250
EE L + + + +++ K L E D K A E + Q++ E
Sbjct: 1203 TALEELSEQLEQAKRFKANLEKNKQGL---ETDNK---------ELACEVKVLQQVKAES 1250
Query: 251 QQEKALLQARVQELEASVQEG-----KLDRSSPYIQ--------VLEEDWRQALRDHQEQ 297
+ ++ L A+VQEL A V EG +L + +Q +LEE ++ ++ ++
Sbjct: 1251 EHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDA 1310
Query: 298 ANTIFSLR--KDLRQGEAR-------RLRCM-EEKEMFELQCLALRKDSKMYKDRIEAIL 347
A+ L+ ++L Q E R R+R + EEK + Q + K + ++ A+
Sbjct: 1311 ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQ 1370
Query: 348 LQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQ 396
Q+ + + D + T E L + L++ +AL +++ E D+L+
Sbjct: 1371 SQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLE 1419
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 63.2 bits (152), Expect = 5e-10
Identities = 93/380 (24%), Positives = 173/380 (45%), Gaps = 62/380 (16%)
Query: 113 SGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQ------ERVQRLKE 166
+ LT L T +Q++ Q+L L + K+ ++ +L ++ Q +V++L
Sbjct: 501 ASLTSELTTLNATIQQQDQELAGLKQQAKE--KQAQLAQTLQQQEQASQGLRHQVEQLSS 558
Query: 167 ECEAGSRELKRCKEEN----YDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAED 222
+ ++LK E+ D A +LA +EE+ A+L R RD L+ QL+ ++ E
Sbjct: 559 SLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASL-RERDAALK--QLE--ALEKEK 613
Query: 223 DCKVERKHTLKLRHAMEQRPS-QELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQ 281
K+E +L+ A E R S Q + + Q+EKA L +V+EL+A V+ + ++ Q
Sbjct: 614 AAKLEILQQ-QLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQ 672
Query: 282 VLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKD 341
V E + + LR Q++A + R +EK+ + Q AL++ K+ K
Sbjct: 673 VAELELQ--LRSEQQKA--------------TEKERVAQEKDQLQEQLQALKESLKVTKG 716
Query: 342 RIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRE--LGEKADELQLQ- 398
+E + + E+ + I+ EL A+ +++ RK++ E G K E +LQ
Sbjct: 717 SLEEEKRRAADALEEQQRCIS---ELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQ 773
Query: 399 ---VFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQD-LEDTQLSDKGC 454
Q E ++ LRR+ E + E + +E++ ++ ED+Q
Sbjct: 774 LGEAHQAETEV------LRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQ------ 821
Query: 455 LAGGGSPKQPFAALHQEQVL 474
+ + A+ QEQ++
Sbjct: 822 -----QEEAQYGAMFQEQLM 836
Score = 45.4 bits (106), Expect = 1e-04
Identities = 78/361 (21%), Positives = 150/361 (41%), Gaps = 45/361 (12%)
Query: 117 QLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRK---HQERVQR--LKEECEAG 171
Q + + ++ QK DL+ L KE+ ++L+RK QE R +KE AG
Sbjct: 886 QQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAG 945
Query: 172 SRELKRCKEEN--YDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERK 229
R+ + +E+ + + A Q+ E+ A M N E+++L+ +LM+++ + ER
Sbjct: 946 DRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGN-----ELERLRAALMESQGQQQEER- 999
Query: 230 HTLKLRHAMEQRPSQELLWE---LQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEED 286
++R L E Q + AL +A ELE +Q L+ L+E
Sbjct: 1000 -------GQQEREVARLTQERGRAQADLALEKAARAELEMRLQNA-LNEQRVEFATLQEA 1051
Query: 287 WRQALRDHQEQANTIFSLR----------KDLRQGEARRLRCMEEKEMFELQCLALRKDS 336
AL + + + + LR ++LRQ + + +KE + ++
Sbjct: 1052 LAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEA 1111
Query: 337 KMYKD----RIEAILLQM----EEVAIERDQAIATREELHAQHARGLQEKDALRKQVREL 388
+ ++EA+ ++ ++ +++QA + L A+ A + AL +L
Sbjct: 1112 AGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQL 1171
Query: 389 GEKADEL---QLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
EKA EL Q + + +L A +++ + + G ++ SL LE
Sbjct: 1172 EEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLE 1231
Query: 446 D 446
+
Sbjct: 1232 E 1232
Score = 44.7 bits (104), Expect = 2e-04
Identities = 87/384 (22%), Positives = 153/384 (39%), Gaps = 41/384 (10%)
Query: 97 KEPARVFSMIIDASGESGLTQLLMTE--VMKLQKKVQDLTALLSSKDDFIKELRVKDSLL 154
KEPAR + E Q T+ + ++++ + + L + E + +
Sbjct: 939 KEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEE 998
Query: 155 RKHQER-VQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQL 213
R QER V RL +E +L K +L MRL + E+ ++E L
Sbjct: 999 RGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQ----------RVEFATL 1048
Query: 214 KHSLMKAEDDCKVERKHTLKLR--HAMEQRPSQELLWELQQEKALLQARVQELEA----- 266
+ +L A + + + + KLR A + + +EL ++Q K L + +E +
Sbjct: 1049 QEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQ 1108
Query: 267 SVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFE 326
S G+ + + P ++ L + + + Q+Q SL + L EA R E E
Sbjct: 1109 SEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSL---EAERASRAERDSALE 1165
Query: 327 LQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA---IATREELHAQHARGLQEKDALRK 383
L + ++ A+ E+A R + +E AQ ARG QE +
Sbjct: 1166 TLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNS 1225
Query: 384 QVRELGEKADELQLQVFQCEAQ-------LLA-------VEGRLRRQQLETLVLSS-DLE 428
+ L E+ L QV + E + ++A +E RLR Q ET S+ E
Sbjct: 1226 LISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAE 1285
Query: 429 DGSPRRSQELSLPQDLEDTQLSDK 452
S R + SL ++ E +++ +
Sbjct: 1286 RSSALREEVQSLREEAEKQRVASE 1309
Score = 43.9 bits (102), Expect = 3e-04
Identities = 78/351 (22%), Positives = 145/351 (41%), Gaps = 39/351 (11%)
Query: 110 SGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERV---Q 162
S ++ +TQ E +L +KV++L A + + E + + + LR Q++ +
Sbjct: 633 SAQTSVTQA-QREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKE 691
Query: 163 RLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAED 222
R+ +E + +L+ KE L + EEK A + Q I +LK +
Sbjct: 692 RVAQEKDQLQEQLQALKES---LKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVE 748
Query: 223 DCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDR---SSPY 279
K ERK + E+ + L LQQ QA + L + E + S
Sbjct: 749 QHKRERKELEE-----ERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESEC 803
Query: 280 IQVLEE--DWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSK 337
Q+++E WR+ D Q++ + + G + + M KE +C R++ +
Sbjct: 804 EQLVKEVAAWRERYEDSQQE---------EAQYGAMFQEQLMTLKE----ECEKARQELQ 850
Query: 338 MYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQL 397
K+++ I E + +A ELHA AR LQ+ + ++L + LQ
Sbjct: 851 EAKEKVAGIESHSELQISRQQNELA---ELHANLARALQQVQEKEVRAQKLADDLSTLQE 907
Query: 398 QVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQ 448
++ ++ +E +R+ + S +L P R+ + P+ LE+ Q
Sbjct: 908 KMAATSKEVARLETLVRKAGEQQETASRELVK-EPARAGDRQ-PEWLEEQQ 956
Score = 42.7 bits (99), Expect = 7e-04
Identities = 79/360 (21%), Positives = 144/360 (40%), Gaps = 63/360 (17%)
Query: 69 QRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQK 128
+R G KG A L+ L + Q +V +E A +M + ES QL
Sbjct: 760 ERAGRKGLEARLQQLGEAH-QAETEVLRRELAE--AMAAQHTAESECEQL---------- 806
Query: 129 KVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDL--- 185
V+++ A +D +E ++ QE++ LKEECE +EL+ KE+ +
Sbjct: 807 -VKEVAAWRERYEDSQQEEAQYGAMF---QEQLMTLKEECEKARQELQEAKEKVAGIESH 862
Query: 186 -AMRLAHQSEE-------KGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKL--- 234
++++ Q E AL + ++ ++ +L L ++ K +L
Sbjct: 863 SELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETL 922
Query: 235 -RHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRD 293
R A EQ+ + EL +E A R E Q + + +Q +E R+
Sbjct: 923 VRKAGEQQETASR--ELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAME-------RE 973
Query: 294 HQEQANTIFSLRKDL--RQGEARRLRCMEEKEMFELQC------------------LALR 333
++ N + LR L QG+ + R +E+E+ L L +R
Sbjct: 974 AEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMR 1033
Query: 334 KDSKMYKDRIEAILLQ--MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEK 391
+ + + R+E LQ + E++ +L A ++E + LR+ V++L E+
Sbjct: 1034 LQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQ 1093
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/344 (22%), Positives = 142/344 (41%), Gaps = 74/344 (21%)
Query: 107 IDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRV-------KDSLLRKHQE 159
+ S S + +L T ++++ + L S++D+ EL KD+ + Q+
Sbjct: 197 LSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQ 256
Query: 160 RVQRLK--EECEAGS----RELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQL 213
R+ RL E +A S +EL+ +++N L MRL H++ L + +DL+ E Q+
Sbjct: 257 RIDRLALLNEKQAASPLEPKELEELRDKNESLTMRL-HET------LKQCQDLKTEKSQM 309
Query: 214 KHSLMKAEDDCKVERKHTLKLRH-AMEQRPSQELLWELQQEKALLQARVQELEASVQEGK 272
+ + ++ + KLR A + Q+ L EL +E + +A + LE Q
Sbjct: 310 DRKINQLSEE---NGDLSFKLREFASHLQQLQDALNELTEEHS--KATQEWLEKQAQ--- 361
Query: 273 LDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLAL 332
LE++ AL+D + + ++ QG+ +L E+ + +LQ
Sbjct: 362 ----------LEKELSAALQDKK-----CLEEKNEILQGKLSQL----EEHLSQLQ---- 398
Query: 333 RKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKA 392
+ K + +LQ+E + E A +L A +
Sbjct: 399 -DNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQA---------------------RV 436
Query: 393 DELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQ 436
+ L+ + Q EA+LLA G ++ + L +DL+ SQ
Sbjct: 437 EMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ 480
Score = 39.7 bits (91), Expect = 0.006
Identities = 86/411 (20%), Positives = 165/411 (40%), Gaps = 69/411 (16%)
Query: 106 IIDASGESG-LTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRL 164
+++ GES L +L+M E K QK + L L + + S LR E VQ L
Sbjct: 1241 VLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALR---EEVQSL 1297
Query: 165 KEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMR--NRDLQLEIDQLKHS------ 216
+EE E + ++E A R +E A + ++ L QL+H+
Sbjct: 1298 REEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALV 1357
Query: 217 --LMKAEDDCK--------VERKHTLKLRHAM--------EQRPSQELLWEL-------- 250
L+ A+ C+ E++H +L + E +Q L EL
Sbjct: 1358 SELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVA 1417
Query: 251 QQEKALLQARVQE---------------LEASVQEGKLDRSSPYIQVLEEDWRQALRDHQ 295
+QE+ Q R ++ L A G +R++ Q LE + QA +
Sbjct: 1418 EQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYV 1477
Query: 296 EQ-------ANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILL 348
++ A T + + Q AR L M K +E + + ++ + +++ + +
Sbjct: 1478 QELAAVRADAETRLAEVQREAQSTARELEVMTAK--YEGAKVKVLEERQRFQEERQKLTA 1535
Query: 349 QMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLA 408
Q+E++ + + + EEL + A Q +++++ + + E Q + + +AQL
Sbjct: 1536 QVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNE 1595
Query: 409 VEGRLRRQQLETLVLSSDLE------DGSPRRSQELSLP-QDLEDTQLSDK 452
++ +L +++ +E D +++QEL + LE Q +K
Sbjct: 1596 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENK 1646
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 62.8 bits (151), Expect = 7e-10
Identities = 75/340 (22%), Positives = 149/340 (43%), Gaps = 41/340 (12%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
E+ LQ K++D AL IKEL Q R++ L+EE EA + +++
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKEL----------QARIEELEEEIEAERASRAKAEKQ 1141
Query: 182 NYDLAMRL---AHQSEEKGAA----LMRNRDLQLEIDQLKHSLMKA-----EDDCKVERK 229
DL+ L + + EE G A + N+ + E +++ L +A + +K
Sbjct: 1142 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201
Query: 230 HTLKLRHAMEQRPS-QELLWELQQEKALLQARVQELEASVQ-----EGKLDRSSPYIQVL 283
H + EQ + Q + +L++EK+ ++ + +L ++V+ +G L++ ++
Sbjct: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Query: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343
+ + + Q N + + R L+ R ++EKE Q L + + + +I
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQ---LSRGKQAFTQQI 1318
Query: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403
E + Q+EE I+ A+A HA + + D LR+Q E E ELQ + +
Sbjct: 1319 EELKRQLEE-EIKAKNALA-----HALQS-SRHDCDLLREQYEEEQESKAELQRALSKAN 1371
Query: 404 AQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQD 443
+ V + + + + + +LE+ + +Q L ++
Sbjct: 1372 TE---VAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
Score = 57.0 bits (136), Expect = 4e-08
Identities = 82/387 (21%), Positives = 157/387 (40%), Gaps = 51/387 (13%)
Query: 89 QLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDD----FI 144
Q K+ KE + + I D + + K+ + ++D + L SK++ I
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 145 KELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNR 204
+L + L+ R +E EA +L R K+ L Q EE+ A
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAK---- 1332
Query: 205 DLQLEIDQLKHSLMKAEDDCKV-------ERKHTLKLRHAMEQRPSQELLWELQQEKALL 257
+ L H+L + DC + E++ +L+ A+ + ++ W + E +
Sbjct: 1333 ------NALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAI 1386
Query: 258 QARVQELEASVQE--GKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEAR- 314
Q R +ELE + ++ +L + +++ + + Q N + L D+ + A
Sbjct: 1387 Q-RTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC 1445
Query: 315 -----------------RLRCME---EKEMFELQCLALRKDSKMYKDRIEAILLQMEEVA 354
+ +C E E E + + +L + K+ E L Q+E +
Sbjct: 1446 AALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLK 1505
Query: 355 IER---DQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEG 411
E Q I+ E A+ + + E + ++KQV + EK ELQ + + EA L EG
Sbjct: 1506 RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQ--EKC-ELQAALEEAEASLEHEEG 1562
Query: 412 RLRRQQLETLVLSSDLEDGSPRRSQEL 438
++ R QLE + S+++ + +E+
Sbjct: 1563 KILRIQLELNQVKSEVDRKIAEKDEEI 1589
Score = 44.7 bits (104), Expect = 2e-04
Identities = 72/338 (21%), Positives = 139/338 (41%), Gaps = 69/338 (20%)
Query: 109 ASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEEC 168
A E QL+ T++ +L+ K++++T +++ EL K ++L++EC
Sbjct: 905 ADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKK----------RKLEDEC 953
Query: 169 EAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCK-VE 227
K++ DL + LA +EK A + ++L E+ L ++ K + K ++
Sbjct: 954 S-------ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQ 1006
Query: 228 RKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDW 287
H L + + ++ + L + K L+ +V +LE S+++ K L D
Sbjct: 1007 EAHQQTLD---DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKK---------LRMDL 1054
Query: 288 RQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL 347
+A R L DL+ + + EK+ D K+ K E
Sbjct: 1055 ERAKR----------KLEGDLKLAQESIMDIENEKQQL---------DEKLKKKEFEISN 1095
Query: 348 LQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLL 407
LQ + IE +QA+ G+Q L+K+++EL + +EL+ ++ A
Sbjct: 1096 LQSK---IEDEQAL------------GIQ----LQKKIKELQARIEELEEEIEAERASRA 1136
Query: 408 AVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
E + E +S LE+ S ++ + + E
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1174
Score = 39.3 bits (90), Expect = 0.008
Identities = 60/303 (19%), Positives = 125/303 (41%), Gaps = 44/303 (14%)
Query: 124 MKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSREL-------K 176
++L + ++ ++ KD+ I D L R H V+ ++ +A R K
Sbjct: 1569 LELNQVKSEVDRKIAEKDEEI------DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 177 RCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRH 236
+ + + ++ ++L H + AL R+ Q ++K D ++ L+
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQ--------GILK---DTQIHLDDALR--- 1668
Query: 237 AMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQE 296
Q +E L +++ LLQA ++EL A++++ + R ++L+ R L Q
Sbjct: 1669 --SQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1726
Query: 297 QA--NTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVA 354
+ NT L D+ Q + ++E R + K I + EE+
Sbjct: 1727 TSLINTKKKLETDISQMQGEMEDILQE----------ARNAEEKAKKAITDAAMMAEELK 1776
Query: 355 IERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLR 414
E+D + A E + + +++ + +L K + Q+Q + EA++ +EG +
Sbjct: 1777 KEQDTS-AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ--KLEARVRELEGEVE 1833
Query: 415 RQQ 417
+Q
Sbjct: 1834 SEQ 1836
Score = 37.7 bits (86), Expect = 0.024
Identities = 65/344 (18%), Positives = 144/344 (41%), Gaps = 30/344 (8%)
Query: 109 ASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEEC 168
A + + QL + ++ L A + S++D I+ + + L + + ++
Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642
Query: 169 EAGSRELKRCK------EENYDLAMRLAHQSEEKGAALMRNRDL-QLEIDQLKHSLMKAE 221
R + + + + D A+R +E+ A + R +L Q EI++L+ +L + E
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702
Query: 222 DDCKVERKHTLKLRHAMEQRPSQELLW-----ELQQEKALLQARVQEL--EASVQEGKLD 274
K+ + L ++ +Q +L+ + + +Q ++++ EA E K
Sbjct: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAK 1762
Query: 275 RSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRK 334
++ ++ E+ L+ Q+ + + ++K++ Q ++E E L K
Sbjct: 1763 KAITDAAMMAEE----LKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLAL------K 1812
Query: 335 DSKMYKDRIEAILLQME-EVAIERDQAIATREELHAQHARGLQE----KDALRKQVRELG 389
K ++EA + ++E EV E+ + + L +H R ++E + RK + L
Sbjct: 1813 GGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR-KHERRVKELTYQTEEDRKNILRLQ 1871
Query: 390 EKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPR 433
+ D+LQ +V + Q E + + L +LE+ R
Sbjct: 1872 DLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEER 1915
Score = 34.7 bits (78), Expect = 0.20
Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 9/145 (6%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVKDSL--LRKHQERVQRLKEECEAGSR---ELKRCK 179
+++K ++ L + D ++L +K ++K + RV+ L+ E E+ + E +
Sbjct: 1787 RMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGL 1846
Query: 180 EENYDLAMRLAHQSEEKGAALMRNRDL----QLEIDQLKHSLMKAEDDCKVERKHTLKLR 235
++ L +Q+EE ++R +DL Q ++ K +AE+ KL+
Sbjct: 1847 RKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQ 1906
Query: 236 HAMEQRPSQELLWELQQEKALLQAR 260
H +E+ + + E Q K +++R
Sbjct: 1907 HELEEAEERADIAESQVNKLRVKSR 1931
Score = 30.0 bits (66), Expect = 5.0
Identities = 32/151 (21%), Positives = 69/151 (45%), Gaps = 10/151 (6%)
Query: 305 RKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL---LQMEEVAIERDQAI 361
RK+L E + + ++EK +LQ A + ++R + ++ +Q+E E +
Sbjct: 876 RKEL---EEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERA 932
Query: 362 ATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETL 421
EE++A+ +K L + EL + D+L+L + + E + A E +++ E
Sbjct: 933 EDEEEINAELTA---KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMA 989
Query: 422 VLSSDLED-GSPRRSQELSLPQDLEDTQLSD 451
L + +++ + + Q L+D Q +
Sbjct: 990 GLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Score = 29.3 bits (64), Expect = 8.5
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 17/114 (14%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
EV QK+ + L + +KEL + RK+ R+Q L ++ +A + KR EE
Sbjct: 1831 EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1890
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLR 235
E+ L + R LQ H L +AE+ + KLR
Sbjct: 1891 ----------AEEQSNTNLAKFRKLQ-------HELEEAEERADIAESQVNKLR 1927
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 62.8 bits (151), Expect = 7e-10
Identities = 75/340 (22%), Positives = 149/340 (43%), Gaps = 41/340 (12%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
E+ LQ K++D AL IKEL Q R++ L+EE EA + +++
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKEL----------QARIEELEEEIEAERASRAKAEKQ 1141
Query: 182 NYDLAMRL---AHQSEEKGAA----LMRNRDLQLEIDQLKHSLMKA-----EDDCKVERK 229
DL+ L + + EE G A + N+ + E +++ L +A + +K
Sbjct: 1142 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201
Query: 230 HTLKLRHAMEQRPS-QELLWELQQEKALLQARVQELEASVQ-----EGKLDRSSPYIQVL 283
H + EQ + Q + +L++EK+ ++ + +L ++V+ +G L++ ++
Sbjct: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Query: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343
+ + + Q N + + R L+ R ++EKE Q L + + + +I
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQ---LSRGKQAFTQQI 1318
Query: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403
E + Q+EE I+ A+A HA + + D LR+Q E E ELQ + +
Sbjct: 1319 EELKRQLEE-EIKAKNALA-----HALQS-SRHDCDLLREQYEEEQESKAELQRALSKAN 1371
Query: 404 AQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQD 443
+ V + + + + + +LE+ + +Q L ++
Sbjct: 1372 TE---VAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
Score = 57.0 bits (136), Expect = 4e-08
Identities = 82/387 (21%), Positives = 157/387 (40%), Gaps = 51/387 (13%)
Query: 89 QLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDD----FI 144
Q K+ KE + + I D + + K+ + ++D + L SK++ I
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 145 KELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNR 204
+L + L+ R +E EA +L R K+ L Q EE+ A
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAK---- 1332
Query: 205 DLQLEIDQLKHSLMKAEDDCKV-------ERKHTLKLRHAMEQRPSQELLWELQQEKALL 257
+ L H+L + DC + E++ +L+ A+ + ++ W + E +
Sbjct: 1333 ------NALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAI 1386
Query: 258 QARVQELEASVQE--GKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEAR- 314
Q R +ELE + ++ +L + +++ + + Q N + L D+ + A
Sbjct: 1387 Q-RTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC 1445
Query: 315 -----------------RLRCME---EKEMFELQCLALRKDSKMYKDRIEAILLQMEEVA 354
+ +C E E E + + +L + K+ E L Q+E +
Sbjct: 1446 AALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLK 1505
Query: 355 IER---DQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEG 411
E Q I+ E A+ + + E + ++KQV + EK ELQ + + EA L EG
Sbjct: 1506 RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQ--EKC-ELQAALEEAEASLEHEEG 1562
Query: 412 RLRRQQLETLVLSSDLEDGSPRRSQEL 438
++ R QLE + S+++ + +E+
Sbjct: 1563 KILRIQLELNQVKSEVDRKIAEKDEEI 1589
Score = 44.7 bits (104), Expect = 2e-04
Identities = 72/338 (21%), Positives = 139/338 (41%), Gaps = 69/338 (20%)
Query: 109 ASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEEC 168
A E QL+ T++ +L+ K++++T +++ EL K ++L++EC
Sbjct: 905 ADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKK----------RKLEDEC 953
Query: 169 EAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCK-VE 227
K++ DL + LA +EK A + ++L E+ L ++ K + K ++
Sbjct: 954 S-------ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQ 1006
Query: 228 RKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDW 287
H L + + ++ + L + K L+ +V +LE S+++ K L D
Sbjct: 1007 EAHQQTLD---DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKK---------LRMDL 1054
Query: 288 RQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL 347
+A R L DL+ + + EK+ D K+ K E
Sbjct: 1055 ERAKR----------KLEGDLKLAQESIMDIENEKQQL---------DEKLKKKEFEISN 1095
Query: 348 LQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLL 407
LQ + IE +QA+ G+Q L+K+++EL + +EL+ ++ A
Sbjct: 1096 LQSK---IEDEQAL------------GIQ----LQKKIKELQARIEELEEEIEAERASRA 1136
Query: 408 AVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
E + E +S LE+ S ++ + + E
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1174
Score = 39.3 bits (90), Expect = 0.008
Identities = 60/303 (19%), Positives = 125/303 (41%), Gaps = 44/303 (14%)
Query: 124 MKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSREL-------K 176
++L + ++ ++ KD+ I D L R H V+ ++ +A R K
Sbjct: 1569 LELNQVKSEVDRKIAEKDEEI------DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 177 RCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRH 236
+ + + ++ ++L H + AL R+ Q ++K D ++ L+
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQ--------GILK---DTQIHLDDALR--- 1668
Query: 237 AMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQE 296
Q +E L +++ LLQA ++EL A++++ + R ++L+ R L Q
Sbjct: 1669 --SQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1726
Query: 297 QA--NTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVA 354
+ NT L D+ Q + ++E R + K I + EE+
Sbjct: 1727 TSLINTKKKLETDISQMQGEMEDILQE----------ARNAEEKAKKAITDAAMMAEELK 1776
Query: 355 IERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLR 414
E+D + A E + + +++ + +L K + Q+Q + EA++ +EG +
Sbjct: 1777 KEQDTS-AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ--KLEARVRELEGEVE 1833
Query: 415 RQQ 417
+Q
Sbjct: 1834 SEQ 1836
Score = 37.7 bits (86), Expect = 0.024
Identities = 65/344 (18%), Positives = 144/344 (41%), Gaps = 30/344 (8%)
Query: 109 ASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEEC 168
A + + QL + ++ L A + S++D I+ + + L + + ++
Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642
Query: 169 EAGSRELKRCK------EENYDLAMRLAHQSEEKGAALMRNRDL-QLEIDQLKHSLMKAE 221
R + + + + D A+R +E+ A + R +L Q EI++L+ +L + E
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702
Query: 222 DDCKVERKHTLKLRHAMEQRPSQELLW-----ELQQEKALLQARVQEL--EASVQEGKLD 274
K+ + L ++ +Q +L+ + + +Q ++++ EA E K
Sbjct: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAK 1762
Query: 275 RSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRK 334
++ ++ E+ L+ Q+ + + ++K++ Q ++E E L K
Sbjct: 1763 KAITDAAMMAEE----LKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLAL------K 1812
Query: 335 DSKMYKDRIEAILLQME-EVAIERDQAIATREELHAQHARGLQE----KDALRKQVRELG 389
K ++EA + ++E EV E+ + + L +H R ++E + RK + L
Sbjct: 1813 GGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR-KHERRVKELTYQTEEDRKNILRLQ 1871
Query: 390 EKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPR 433
+ D+LQ +V + Q E + + L +LE+ R
Sbjct: 1872 DLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEER 1915
Score = 34.7 bits (78), Expect = 0.20
Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 9/145 (6%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVKDSL--LRKHQERVQRLKEECEAGSR---ELKRCK 179
+++K ++ L + D ++L +K ++K + RV+ L+ E E+ + E +
Sbjct: 1787 RMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGL 1846
Query: 180 EENYDLAMRLAHQSEEKGAALMRNRDL----QLEIDQLKHSLMKAEDDCKVERKHTLKLR 235
++ L +Q+EE ++R +DL Q ++ K +AE+ KL+
Sbjct: 1847 RKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQ 1906
Query: 236 HAMEQRPSQELLWELQQEKALLQAR 260
H +E+ + + E Q K +++R
Sbjct: 1907 HELEEAEERADIAESQVNKLRVKSR 1931
Score = 30.0 bits (66), Expect = 5.0
Identities = 32/151 (21%), Positives = 69/151 (45%), Gaps = 10/151 (6%)
Query: 305 RKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL---LQMEEVAIERDQAI 361
RK+L E + + ++EK +LQ A + ++R + ++ +Q+E E +
Sbjct: 876 RKEL---EEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERA 932
Query: 362 ATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETL 421
EE++A+ +K L + EL + D+L+L + + E + A E +++ E
Sbjct: 933 EDEEEINAELTA---KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMA 989
Query: 422 VLSSDLED-GSPRRSQELSLPQDLEDTQLSD 451
L + +++ + + Q L+D Q +
Sbjct: 990 GLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Score = 29.3 bits (64), Expect = 8.5
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 17/114 (14%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
EV QK+ + L + +KEL + RK+ R+Q L ++ +A + KR EE
Sbjct: 1831 EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1890
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLR 235
E+ L + R LQ H L +AE+ + KLR
Sbjct: 1891 ----------AEEQSNTNLAKFRKLQ-------HELEEAEERADIAESQVNKLR 1927
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 62.4 bits (150), Expect = 9e-10
Identities = 77/352 (21%), Positives = 155/352 (44%), Gaps = 52/352 (14%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRC 178
+ T++ ++ K+QD S + +KE + K L + E ++ ++ EA S E+K
Sbjct: 686 ITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKAS 745
Query: 179 KEE-----------NYDLAMRLAHQSE----EKGAALMRNRDLQLE---IDQLKHSLMKA 220
KE+ N DL +R S+ EK DLQ + ++ +K L K
Sbjct: 746 KEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQ 805
Query: 221 EDDCKVERK------HTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLD 274
E++ ++ ++ K++H Q + ELQ+ K +A + EL S + KL
Sbjct: 806 EEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTEL--STVKDKLS 863
Query: 275 RSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRK 334
+ S ++ + ++ +++Q+ I L K C E K ++Q K
Sbjct: 864 KVSDSLKNSKSEFE---KENQKGKAAILDLEK----------TCKELKHQLQVQMENTLK 910
Query: 335 DSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALR---KQVRELGEK 391
+ K K +E E++ + + EL++ + +Q ++ L+ K+ ++L
Sbjct: 911 EQKELKKSLEK----------EKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGN 960
Query: 392 ADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQD 443
+EL+ Q + Q+ A++G L+ L+ L + L+ + +QEL+ ++
Sbjct: 961 INELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKE 1012
Score = 57.0 bits (136), Expect = 4e-08
Identities = 67/347 (19%), Positives = 149/347 (42%), Gaps = 49/347 (14%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
E+ K+ ++ +TA L K + +L +S L++++E+ L+++ E ++K+ + +
Sbjct: 682 ELNKITTQLDQVTAKLQDKQEHCSQL---ESHLKEYKEKYLSLEQKTEELEGQIKKLEAD 738
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ ++ ++ N DL+L +L L ++ R K A+E
Sbjct: 739 SLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES- 797
Query: 242 PSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTI 301
++ L + ++EK +L+ Q+ E QE K+ H+E N I
Sbjct: 798 -IKQKLTKQEEEKQILK---QDFETLSQETKIQ-------------------HEELNNRI 834
Query: 302 FSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIE-------AILLQMEEVA 354
+ +L++ + + M E + + + K K E A +L +E+
Sbjct: 835 QTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTC 894
Query: 355 IERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLR 414
E + +L Q L+E+ L+K + + E + +L+L++ + QL+ + L+
Sbjct: 895 KE------LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLK 948
Query: 415 RQQLETLVLS---SDLEDGSPRRSQELSLPQD------LEDTQLSDK 452
+ + E L ++L+ S ++ +++ Q L+ T+L +K
Sbjct: 949 QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENK 995
Score = 55.1 bits (131), Expect = 1e-07
Identities = 92/330 (27%), Positives = 145/330 (43%), Gaps = 61/330 (18%)
Query: 131 QDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLA 190
Q L + LS+ + + + V+ L + E Q+LKEE + + K E +L
Sbjct: 347 QQLQSRLSASETSLHRIHVE---LSEKGEATQKLKEELSEVETKYQHLKAE----FKQLQ 399
Query: 191 HQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQRP-SQELLWE 249
Q EEK LQ EI+QL L++ E E LK EQR S E L +
Sbjct: 400 QQREEKE---QHGLQLQSEINQLHSKLLETERQLG-EAHGRLK-----EQRQLSSEKLMD 450
Query: 250 LQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLR 309
+Q+ A LQ ++ LE ++E K+ S+ L++ +Q HQEQ + L+
Sbjct: 451 KEQQVADLQLKLSRLEEQLKE-KVTNSTELQHQLDKTKQQ----HQEQ--------QALQ 497
Query: 310 QGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEE--VAIERDQAIATREEL 367
Q +LR E + E Q L D +EA+L + +E +E++ RE+L
Sbjct: 498 QSTTAKLR--EAQNDLE-QVLRQIGDKDQKIQNLEALLQKSKENISLLEKE-----REDL 549
Query: 368 HAQHARG---------LQEKD-ALRKQVRELGEK-----------ADELQLQVFQCEAQL 406
+A+ G LQEK+ L++QV +L EK + L QV + +A L
Sbjct: 550 YAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHL 609
Query: 407 LAVEGRLRRQQLETLVLSSDLEDGSPRRSQ 436
A + R+ + L+S L + + SQ
Sbjct: 610 RAAQDRVLSLETSVNELNSQLNESKEKVSQ 639
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/351 (18%), Positives = 150/351 (42%), Gaps = 53/351 (15%)
Query: 101 RVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQER 160
+V + + + E+ + Q L TE+++ + ++D+ L K + ++ + D++ + +
Sbjct: 192 KVTRLTEELNKEATVIQDLKTELLQ-RPGIEDVAVL---KKELVQVQTLMDNMTLERERE 247
Query: 161 VQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQL------- 213
++LK+EC+ + + L LA +E + + L+ +++L
Sbjct: 248 SEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTL 307
Query: 214 -KHSLMKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGK 272
++ L K +D K+E KH ++ ++ Q L + + LQ+R+ E S+
Sbjct: 308 TENLLKKEQDYTKLEEKHN---EESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIH 364
Query: 273 LDRSSPYIQVLEEDWRQALRDHQEQANTIFS-LRKDLRQGEARRLRCMEEKEMFELQCLA 331
++ S + + Q L++ + T + L+ + +Q + +R EEKE LQ
Sbjct: 365 VELSE------KGEATQKLKEELSEVETKYQHLKAEFKQLQQQR----EEKEQHGLQ--- 411
Query: 332 LRKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEK 391
+++ + Q+ +E T +L H R L++Q + EK
Sbjct: 412 -----------LQSEINQLHSKLLE------TERQLGEAHGR-------LKEQRQLSSEK 447
Query: 392 ADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQ 442
+ + QV + +L +E +L+ + + L L+ + ++ +L Q
Sbjct: 448 LMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQ 498
Score = 47.4 bits (111), Expect = 3e-05
Identities = 79/345 (22%), Positives = 155/345 (44%), Gaps = 57/345 (16%)
Query: 118 LLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECE-------A 170
L + KL++ DL +L D ++++ ++LL+K +E + L++E E A
Sbjct: 496 LQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQA 555
Query: 171 GSRE---LKRCKEENY-------DLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKA 220
G E L + +E+N+ L +L +QSE A +L ++ + K L A
Sbjct: 556 GEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQA---QENLHDQVQEQKAHLRAA 612
Query: 221 EDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQ---ELEASVQEGKLDRSS 277
+D L L ++ + SQ L E +++ + L +++ EL S + K + +
Sbjct: 613 QD-------RVLSLETSVNELNSQ--LNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRA 663
Query: 278 PYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSK 337
+Q + + AL+D Q++ N I + L Q A+ +++K+ C L K
Sbjct: 664 D-LQNHLDTAQNALQDKQQELNKITT---QLDQVTAK----LQDKQE---HCSQLESHLK 712
Query: 338 MYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQL 397
YK++ ++ + EE+ + + A E+ A + LQ+ R+ +L +A EL
Sbjct: 713 EYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSK 772
Query: 398 QV-------------FQCEAQLL-AVEGRLRRQQLETLVLSSDLE 428
Q+ Q +++ L +++ +L +Q+ E +L D E
Sbjct: 773 QLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFE 817
Score = 44.7 bits (104), Expect = 2e-04
Identities = 86/411 (20%), Positives = 167/411 (40%), Gaps = 81/411 (19%)
Query: 111 GESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVK--------------DSLLRK 156
GES L L +V L+++VQDL A L + + +EL+ + D L+
Sbjct: 74 GESNLA-LKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTD 132
Query: 157 HQERVQRLKEECEAGSRE---LKRCKE-----------------ENYDLAMRLAHQSEEK 196
+Q L+++ E E +K+ K+ YD L +E+K
Sbjct: 133 SSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQK 192
Query: 197 GAALMRN--------RDLQLEIDQ---------LKHSLMKAE---DDCKVERKH------ 230
L +DL+ E+ Q LK L++ + D+ +ER+
Sbjct: 193 VTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLK 252
Query: 231 ----TLKLRHAMEQRPSQELLWEL---QQEKALLQARVQELEASVQE--GKLDRSSPYIQ 281
L+ ++A + +L EL QE A+ +Q+L++SV E K + +
Sbjct: 253 DECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLL 312
Query: 282 VLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKD 341
E+D+ + H E++ + +++ L Q + L C + + +L + +
Sbjct: 313 KKEQDYTKLEEKHNEESVSKKNIQATLHQ---KDLDCQQLQSRLSASETSLHRIHVELSE 369
Query: 342 RIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQ 401
+ EA EE++ + + L A+ + Q+++ + +L + ++L ++ +
Sbjct: 370 KGEATQKLKEELS----EVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLE 425
Query: 402 CEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDK 452
E QL GRL+ Q+ LSS+ ++ +L L + QL +K
Sbjct: 426 TERQLGEAHGRLKEQR----QLSSEKLMDKEQQVADLQLKLSRLEEQLKEK 472
Score = 36.6 bits (83), Expect = 0.053
Identities = 53/240 (22%), Positives = 103/240 (42%), Gaps = 48/240 (20%)
Query: 36 QCKVLNPDDEEQVLSDPNLVIRKRKVGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVT 95
+CK L +E+ L + LV K K+ + +I R K E L+ + + K++T
Sbjct: 1101 RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQ-EKEITKLNEELKSHKLESIKEIT 1159
Query: 96 GKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLR 155
+ A+ QLL+ + ++LQ K L A + + + ++ ++
Sbjct: 1160 NLKDAK---------------QLLIQQKLELQGKADSLKAAVEQEK---RNQQILKDQVK 1201
Query: 156 KHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKH 215
K +E ++ KE E ++ KE+ ++ M+ ++E K L ++I L
Sbjct: 1202 KEEEELK--KEFIEKEAKLHSEIKEK--EVGMKKHEENEAK---------LTMQITALNE 1248
Query: 216 SLMKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDR 275
+L T+K E + SQ + EL+++ L+ + LEA+VQ + +R
Sbjct: 1249 NL------------GTVK----KEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDER 1292
Score = 33.1 bits (74), Expect = 0.59
Identities = 33/159 (20%), Positives = 70/159 (44%), Gaps = 9/159 (5%)
Query: 58 KRKVGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTG----KEPARVFSMIIDASGES 113
KR +L D +++ + F+E + ++ +K G +E +M I A E+
Sbjct: 1190 KRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNEN 1249
Query: 114 GLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSR 173
L T + Q + ++ L DD E+ V ++ ++ +Q+ + L E C G
Sbjct: 1250 -----LGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEG 1304
Query: 174 ELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQ 212
E+++ + + +L +L + + N+ LQ++ Q
Sbjct: 1305 EIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQ 1343
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 61.6 bits (148), Expect = 2e-09
Identities = 75/334 (22%), Positives = 157/334 (47%), Gaps = 34/334 (10%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYD 184
+L++KV +LT L ++ +KE D L K +++ L E+ E S E+K EEN
Sbjct: 640 ELEQKVNELTGGL---EETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNK 696
Query: 185 LAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQRPSQ 244
L+ SE+K +RDL++ + Q + ++K E ++E+K L + EQ
Sbjct: 697 LS------SEKK----QLSRDLEVFLSQKEDVILK-EHITQLEKKLQLMVE---EQDNLN 742
Query: 245 ELLWELQQEKALLQAR----VQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
+LL Q +K ++ + ++E+ + V E ++ + VL+ + ++E+ N
Sbjct: 743 KLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKD--VVNVLQAVGESLAKINEEKCNL 800
Query: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
F + + + E + ++C++E+ + +QC L+ + Y+ + ++EE+ E++
Sbjct: 801 AFQRDEKVLELE-KEIKCLQEESV--VQCEELKSLLRDYEQEKVLLRKELEEIQSEKEAL 857
Query: 361 IATREELHAQHARGLQEKDALRKQVRELGE--KADELQLQVFQC------EAQLLAVEGR 412
+ E+ + + E L QV E+ + E+ + +C + L +
Sbjct: 858 QSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKE 917
Query: 413 LRRQQLETLVLSSDLEDGSPRRSQELSLPQDLED 446
LR ++ E ++L L ++ LS ++LE+
Sbjct: 918 LRDRRAELILLKDSLAKSPSVKNDPLSSVKELEE 951
Score = 50.4 bits (119), Expect = 4e-06
Identities = 80/410 (19%), Positives = 170/410 (41%), Gaps = 31/410 (7%)
Query: 44 DEEQVLSDPNLVIRKRKVGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARVF 103
+E+ L + NL+I+ +V + K F++ E P L +K A +
Sbjct: 868 NEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEK-CFIKEHENLKPLLEQKELRDRRAELI 926
Query: 104 SMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKH----QE 159
+ + + ++ V +L++K+++L K++ I ++++ +K ++
Sbjct: 927 LLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRK 986
Query: 160 RVQRLKEECE----------AGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLE 209
Q +KEE E A R+L + E +L + QSE+ R + +
Sbjct: 987 ETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHR 1046
Query: 210 IDQLKHSLMKAEDDCKVERKHTLKLRHAMEQRPSQELL-----WELQQEKALLQARVQEL 264
I+ L L + C+ L +E S L E+Q+ KA++ + E
Sbjct: 1047 IEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKEL-EA 1105
Query: 265 EASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCME---- 320
E +E K+ + + LEE Q ++ ++ T+ L + + L ME
Sbjct: 1106 EKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADY 1165
Query: 321 EKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDA 380
E+ M EL K++K+ +D + I +Q ++ +++ + + + + + K
Sbjct: 1166 ERLMKELNQKLTNKNNKI-EDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQL 1224
Query: 381 LRKQVRELGE----KADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSD 426
L K +EL + + D L LQ + +L A + ++ +++ ++S+
Sbjct: 1225 LVKTKKELADSKQAETDHLILQA-SLKGELEASQQQVEVYKIQLAEITSE 1273
Score = 47.8 bits (112), Expect = 2e-05
Identities = 65/260 (25%), Positives = 109/260 (41%), Gaps = 41/260 (15%)
Query: 92 KKVTGKEPARVFSMIIDAS--GESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRV 149
K++ + A +I+ AS GE +Q EV K+Q L + S K + L+
Sbjct: 1230 KELADSKQAETDHLILQASLKGELEASQQ-QVEVYKIQ-----LAEITSEKHKIHEHLKT 1283
Query: 150 K----DSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAH-----------QSE 194
L +Q+RV L+EEC A E E +R+ + Q+E
Sbjct: 1284 SAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAE 1343
Query: 195 EKGAALMRNRDLQLEIDQLKHSLMKAEDDCK--VERKHTLKLRHAMEQRPSQELLWELQQ 252
+GA R L++ IDQLK L ++++ + V TL+ H ++L Q
Sbjct: 1344 TEGAKQEREH-LEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKML----Q 1398
Query: 253 EKALLQARVQELEASVQEGKLDRSSPYIQ----------VLEEDWRQALRDHQEQ-ANTI 301
E +A ++E S+Q + S + Q VL +R +R QE+ T+
Sbjct: 1399 ETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTV 1458
Query: 302 FSLRKDLRQGEARRLRCMEE 321
+L++ L + EA+ + E
Sbjct: 1459 ETLQQQLSKMEAQLFQLKNE 1478
Score = 45.8 bits (107), Expect = 9e-05
Identities = 79/350 (22%), Positives = 147/350 (42%), Gaps = 57/350 (16%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVK-DSLLRKHQERVQRLKEECEAGSRELKR 177
L + LQ+K LS +D +KEL K +SL + + + +LK E K+
Sbjct: 557 LENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKK 616
Query: 178 CKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHA 237
C+ E L + L + E+ + N +L+ ++++L L E+ K + ++ KL
Sbjct: 617 CEREE-RLILELGKKVEQ---TIQYNSELEQKVNELTGGL---EETLKEKDQNDQKLEKL 669
Query: 238 MEQRPSQELLWELQQEKALLQARVQEL-----EASVQEGKLDR------SSPYIQVLEED 286
M Q + L ++K +L A V+ L + S ++ +L R S +L+E
Sbjct: 670 MVQ------MKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEH 723
Query: 287 WRQALRDHQEQANTIFSLRKDLRQGEARRL------------------RCMEEKEMFEL- 327
Q + Q +L K L + ++L EEK++ +
Sbjct: 724 ITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVL 783
Query: 328 ----QCLALRKDSK--MYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDAL 381
+ LA + K + R E +L +E+ +++++ EEL + QEK L
Sbjct: 784 QAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLL 843
Query: 382 RKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGS 431
RK++ E+ + + LQ + LL ++ + +LE L +E+ S
Sbjct: 844 RKELEEIQSEKEALQ-------SDLLEMKNANEKTRLENQNLLIQVEEVS 886
Score = 37.0 bits (84), Expect = 0.041
Identities = 68/288 (23%), Positives = 129/288 (44%), Gaps = 61/288 (21%)
Query: 126 LQKKVQDLTALLSSKDDFIK-ELRVKDSLLR---KHQE----------RVQRLKEECEA- 170
L +K + LS K + IK + V+DS+ + H+E ++ LK E A
Sbjct: 82 LLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAV 141
Query: 171 ------GSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHS-------L 217
L++ EE + + L+ Q + + + + LQ EI++++ L
Sbjct: 142 RSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYL 201
Query: 218 MKAEDDCKVERKHTL-KLRHAME------QRPSQELLWELQQEKALLQARVQELEASVQE 270
K D E+K T+ +L++ +E Q+ L EL Q KA+ Q V+EL ++
Sbjct: 202 QKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIE- 260
Query: 271 GKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDL-RQGEARRLRCMEEKEMFELQC 329
+ ++H+ + N + L+++L +Q EA + +++K EL+
Sbjct: 261 ------------------ASAKEHEAEINKLNELKENLVKQCEASE-KNIQKKYECELEN 301
Query: 330 LALRKDSKMYKDRIEAILLQ----MEEVAIERDQAIA-TREELHAQHA 372
L + ++I +ILLQ +E+V E+ + + T +EL +QH+
Sbjct: 302 LRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHS 349
Score = 32.0 bits (71), Expect = 1.3
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 321 EKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIAT--------REELHAQHA 372
EK E QCL+L+K++ K +E + +M + E +Q+ + EL A +
Sbjct: 84 EKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRS 143
Query: 373 RGLQEKDALRKQVRELGEKADELQLQV 399
+ ++K L+KQ+ E EL Q+
Sbjct: 144 KYSEDKANLQKQLEEAMNTQLELSEQL 170
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 61.6 bits (148), Expect = 2e-09
Identities = 81/346 (23%), Positives = 159/346 (45%), Gaps = 31/346 (8%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGS----RE 174
L T + + ++K ++LT L + + I EL V+ K ++ +++LK + E + +
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 175 LKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAED------DCKVER 228
+ + + +L M+LA + EE AAL R D EI Q ++L K + D + +
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDD---EIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 229 KHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWR 288
R+ E++ ++L EL+ K L+ + A+ QE + R + VL++
Sbjct: 1128 DSERAARNKAEKQ-KRDLGEELEALKTELEDTLDST-ATQQELRAKREQE-VTVLKKALD 1184
Query: 289 QALRDHQEQANTIFSLRKDLRQGEARRLRCMEEK-EMFELQCLALRKDSKMYKDRIEAIL 347
+ R H+ Q +++RQ A+ + + E+ E F+ L K+ + + +
Sbjct: 1185 EETRSHEAQV-------QEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1237
Query: 348 LQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVR-ELGEKADELQLQVFQCEAQL 406
++ + + + +++L AQ + LQ K + ++ R EL +K +LQ +V L
Sbjct: 1238 GELRVLGQAKQEVEHKKKKLEAQ-VQELQSKCSDGERARAELNDKVHKLQNEVESVTGML 1296
Query: 407 LAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDK 452
EG+ + + LSS L+D +QEL + + +S K
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQD-----TQELLQEETRQKLNVSTK 1337
Score = 55.1 bits (131), Expect = 1e-07
Identities = 75/315 (23%), Positives = 132/315 (41%), Gaps = 33/315 (10%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEECEAGSRELKRCKE 180
+LQ+++ DL L ++ + L K D LL + + + +E + E + +
Sbjct: 1424 RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKET 1483
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
+ LA L E K N+ L+ E++ L S + K L ME+
Sbjct: 1484 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1543
Query: 241 RPSQELLWELQQEKALLQARVQELEASVQ--EGKLDRSSPYIQVLEEDWRQALRDHQEQA 298
+Q L EL+ E + LE ++Q +G+ +R +Q +E + R Q Q
Sbjct: 1544 MKTQ--LEELEDELQATEDAKLRLEVNMQALKGQFERD---LQARDEQNEEKRRQLQRQL 1598
Query: 299 NTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL------LQMEE 352
+ + +D R+ A ++ E +L+ L L+ DS + K R EAI QM++
Sbjct: 1599 HEYETELEDERKQRALAAAAKKKLEG-DLKDLELQADSAI-KGREEAIKQLRKLQAQMKD 1656
Query: 353 VAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGR 412
E + A A+R+E+ A +E +KA L+ + Q + L A E
Sbjct: 1657 FQRELEDARASRDEIFA--------------TAKENEKKAKSLEADLMQLQEDLAAAERA 1702
Query: 413 LRRQQLETLVLSSDL 427
++ LE L+ +L
Sbjct: 1703 RKQADLEKEELAEEL 1717
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/322 (21%), Positives = 134/322 (41%), Gaps = 32/322 (9%)
Query: 112 ESGLTQL--LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECE 169
E + QL L ++ Q++++D A S+D+ + + + + + +L+E+
Sbjct: 1641 EEAIKQLRKLQAQMKDFQRELEDARA---SRDEIFATAKENEKKAKSLEADLMQLQEDLA 1697
Query: 170 AGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERK 229
A R K+ E +LA LA + A R L+ I QL+ L + + + +
Sbjct: 1698 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757
Query: 230 HTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQ 289
K EQ L E A ++ Q+ E++ Q+ L+R + ++ +
Sbjct: 1758 RVRKATQQAEQ---------LSNELATERSTAQKNESARQQ--LERQNKELRSKLHEMEG 1806
Query: 290 ALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQ 349
A++ + +TI +L + Q E + + EK+ A K K +++ ILLQ
Sbjct: 1807 AVKSKFK--STIAALEAKIAQLEEQVEQEAREKQ-------AATKSLKQKDKKLKEILLQ 1857
Query: 350 MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAV 409
+E+ ER A +E+ +AR Q L++Q+ E E++ + + + +L
Sbjct: 1858 VED---ERKMAEQYKEQAEKGNARVKQ----LKRQLEEAEEESQRINANRRKLQRELDEA 1910
Query: 410 EGRLRRQQLETLVLSSDLEDGS 431
E L S L G+
Sbjct: 1911 TESNEAMGREVNALKSKLRRGN 1932
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/293 (22%), Positives = 136/293 (46%), Gaps = 28/293 (9%)
Query: 160 RVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMK 219
+V R +EE +A EL++ KE L + E+K + L ++L E ++
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQE-------QLQ 897
Query: 220 AEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPY 279
AE + E + +++R A +++ +E+L E++ AR++E E Q+ + +R
Sbjct: 898 AETELYAEAEE-MRVRLAAKKQELEEILHEME-------ARLEEEEDRGQQLQAERKKMA 949
Query: 280 IQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMY 339
Q+L D + L + +E A L K + + ++L +E + + Q L K+ K+
Sbjct: 950 QQML--DLEEQLEE-EEAARQKLQLEKVTAEAKIKKLE--DEILVMDDQNNKLSKERKLL 1004
Query: 340 KDRIEAI---LLQMEEVAIERDQAIATRE----ELHAQHARGLQEKDALRKQVRELGEKA 392
++RI + L + EE A + E EL + + + + L K R+L A
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1064
Query: 393 DELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
+ Q+ +AQ+ ++ +L +++ E + L+D +++ L ++LE
Sbjct: 1065 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1117
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/279 (23%), Positives = 132/279 (47%), Gaps = 34/279 (12%)
Query: 127 QKKVQDLTALLSSK-DDFIKELRVK-DSLLRKHQERVQRLKEECEAGSRELKRCKEE--- 181
++K + L A K + +K+L ++ DS ++ +E +++L++ +A ++ +R E+
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK-LQAQMKDFQRELEDARA 1666
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ D A ++E+K + L+ ++ QL+ L AE + ++ L+ E+
Sbjct: 1667 SRDEIFATAKENEKKA------KSLEADLMQLQEDLAAAE---RARKQADLEKEELAEEL 1717
Query: 242 PSQ-ELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
S LQ EK L+AR+ +LE ++E ++ + + R+A + ++ +N
Sbjct: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELEE-----EQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
+ + R ++ E+ R + E Q LR SK++ + A+ + + +
Sbjct: 1773 LATERSTAQKNESAR-------QQLERQNKELR--SKLH-EMEGAVKSKFKSTIAALEAK 1822
Query: 361 IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQV 399
IA EE Q AR EK A K +++ +K E+ LQV
Sbjct: 1823 IAQLEEQVEQEAR---EKQAATKSLKQKDKKLKEILLQV 1858
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/345 (21%), Positives = 147/345 (42%), Gaps = 45/345 (13%)
Query: 126 LQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDL 185
L+K+ DL L +E+ K +K + +VQ L+ +C G R ++ + L
Sbjct: 1229 LEKENADLAGELRVLGQAKQEVEHKK---KKLEAQVQELQSKCSDGERARAELNDKVHKL 1285
Query: 186 AMRLAHQS----EEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ + E +G A+ +D+ QL+ + +++ + + + KLR E+R
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 242 PS-QELLWELQQEKALLQARVQELEASVQEGK--LDRSSPYIQVLEEDWRQALRD----- 293
S Q+ L E + K L+ + L + + K L + ++ LEE ++ ++
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Query: 294 --HQEQANTIFSLRKDLRQ-------------GEARRLRCMEEKEMFELQCLALRKD-SK 337
++E+A L K + + + + +E+K+ Q LA K+ S
Sbjct: 1406 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISS 1465
Query: 338 MY---KDRIEAILLQMEEVAIER----DQAIATREELH-------AQHARGLQEKDALRK 383
Y +DR EA + E A+ ++A+ +EEL A+ + KD + K
Sbjct: 1466 KYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK 1525
Query: 384 QVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLE 428
V EL + L+ Q+ + + QL +E L+ + L L +++
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 61.6 bits (148), Expect = 2e-09
Identities = 81/346 (23%), Positives = 159/346 (45%), Gaps = 31/346 (8%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGS----RE 174
L T + + ++K ++LT L + + I EL V+ K ++ +++LK + E + +
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 175 LKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAED------DCKVER 228
+ + + +L M+LA + EE AAL R D EI Q ++L K + D + +
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDD---EIAQKNNALKKIRELEGHISDLQEDL 1134
Query: 229 KHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWR 288
R+ E++ ++L EL+ K L+ + A+ QE + R + VL++
Sbjct: 1135 DSERAARNKAEKQ-KRDLGEELEALKTELEDTLDST-ATQQELRAKREQE-VTVLKKALD 1191
Query: 289 QALRDHQEQANTIFSLRKDLRQGEARRLRCMEEK-EMFELQCLALRKDSKMYKDRIEAIL 347
+ R H+ Q +++RQ A+ + + E+ E F+ L K+ + + +
Sbjct: 1192 EETRSHEAQV-------QEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1244
Query: 348 LQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVR-ELGEKADELQLQVFQCEAQL 406
++ + + + +++L AQ + LQ K + ++ R EL +K +LQ +V L
Sbjct: 1245 GELRVLGQAKQEVEHKKKKLEAQ-VQELQSKCSDGERARAELNDKVHKLQNEVESVTGML 1303
Query: 407 LAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDK 452
EG+ + + LSS L+D +QEL + + +S K
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQD-----TQELLQEETRQKLNVSTK 1344
Score = 55.1 bits (131), Expect = 1e-07
Identities = 75/315 (23%), Positives = 132/315 (41%), Gaps = 33/315 (10%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEECEAGSRELKRCKE 180
+LQ+++ DL L ++ + L K D LL + + + +E + E + +
Sbjct: 1431 RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKET 1490
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
+ LA L E K N+ L+ E++ L S + K L ME+
Sbjct: 1491 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1550
Query: 241 RPSQELLWELQQEKALLQARVQELEASVQ--EGKLDRSSPYIQVLEEDWRQALRDHQEQA 298
+Q L EL+ E + LE ++Q +G+ +R +Q +E + R Q Q
Sbjct: 1551 MKTQ--LEELEDELQATEDAKLRLEVNMQALKGQFERD---LQARDEQNEEKRRQLQRQL 1605
Query: 299 NTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL------LQMEE 352
+ + +D R+ A ++ E +L+ L L+ DS + K R EAI QM++
Sbjct: 1606 HEYETELEDERKQRALAAAAKKKLEG-DLKDLELQADSAI-KGREEAIKQLRKLQAQMKD 1663
Query: 353 VAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGR 412
E + A A+R+E+ A +E +KA L+ + Q + L A E
Sbjct: 1664 FQRELEDARASRDEIFA--------------TAKENEKKAKSLEADLMQLQEDLAAAERA 1709
Query: 413 LRRQQLETLVLSSDL 427
++ LE L+ +L
Sbjct: 1710 RKQADLEKEELAEEL 1724
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/322 (21%), Positives = 134/322 (41%), Gaps = 32/322 (9%)
Query: 112 ESGLTQL--LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECE 169
E + QL L ++ Q++++D A S+D+ + + + + + +L+E+
Sbjct: 1648 EEAIKQLRKLQAQMKDFQRELEDARA---SRDEIFATAKENEKKAKSLEADLMQLQEDLA 1704
Query: 170 AGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERK 229
A R K+ E +LA LA + A R L+ I QL+ L + + + +
Sbjct: 1705 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764
Query: 230 HTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQ 289
K EQ L E A ++ Q+ E++ Q+ L+R + ++ +
Sbjct: 1765 RVRKATQQAEQ---------LSNELATERSTAQKNESARQQ--LERQNKELRSKLHEMEG 1813
Query: 290 ALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQ 349
A++ + +TI +L + Q E + + EK+ A K K +++ ILLQ
Sbjct: 1814 AVKSKFK--STIAALEAKIAQLEEQVEQEAREKQ-------AATKSLKQKDKKLKEILLQ 1864
Query: 350 MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAV 409
+E+ ER A +E+ +AR Q L++Q+ E E++ + + + +L
Sbjct: 1865 VED---ERKMAEQYKEQAEKGNARVKQ----LKRQLEEAEEESQRINANRRKLQRELDEA 1917
Query: 410 EGRLRRQQLETLVLSSDLEDGS 431
E L S L G+
Sbjct: 1918 TESNEAMGREVNALKSKLRRGN 1939
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/293 (22%), Positives = 136/293 (46%), Gaps = 28/293 (9%)
Query: 160 RVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMK 219
+V R +EE +A EL++ KE L + E+K + L ++L E ++
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQE-------QLQ 904
Query: 220 AEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPY 279
AE + E + +++R A +++ +E+L E++ AR++E E Q+ + +R
Sbjct: 905 AETELYAEAEE-MRVRLAAKKQELEEILHEME-------ARLEEEEDRGQQLQAERKKMA 956
Query: 280 IQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMY 339
Q+L D + L + +E A L K + + ++L +E + + Q L K+ K+
Sbjct: 957 QQML--DLEEQLEE-EEAARQKLQLEKVTAEAKIKKLE--DEILVMDDQNNKLSKERKLL 1011
Query: 340 KDRIEAI---LLQMEEVAIERDQAIATRE----ELHAQHARGLQEKDALRKQVRELGEKA 392
++RI + L + EE A + E EL + + + + L K R+L A
Sbjct: 1012 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1071
Query: 393 DELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
+ Q+ +AQ+ ++ +L +++ E + L+D +++ L ++LE
Sbjct: 1072 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1124
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/279 (23%), Positives = 132/279 (47%), Gaps = 34/279 (12%)
Query: 127 QKKVQDLTALLSSK-DDFIKELRVK-DSLLRKHQERVQRLKEECEAGSRELKRCKEE--- 181
++K + L A K + +K+L ++ DS ++ +E +++L++ +A ++ +R E+
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK-LQAQMKDFQRELEDARA 1673
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ D A ++E+K + L+ ++ QL+ L AE + ++ L+ E+
Sbjct: 1674 SRDEIFATAKENEKKA------KSLEADLMQLQEDLAAAE---RARKQADLEKEELAEEL 1724
Query: 242 PSQ-ELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
S LQ EK L+AR+ +LE ++E ++ + + R+A + ++ +N
Sbjct: 1725 ASSLSGRNALQDEKRRLEARIAQLEEELEE-----EQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
+ + R ++ E+ R + E Q LR SK++ + A+ + + +
Sbjct: 1780 LATERSTAQKNESAR-------QQLERQNKELR--SKLH-EMEGAVKSKFKSTIAALEAK 1829
Query: 361 IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQV 399
IA EE Q AR EK A K +++ +K E+ LQV
Sbjct: 1830 IAQLEEQVEQEAR---EKQAATKSLKQKDKKLKEILLQV 1865
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/345 (21%), Positives = 147/345 (42%), Gaps = 45/345 (13%)
Query: 126 LQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDL 185
L+K+ DL L +E+ K +K + +VQ L+ +C G R ++ + L
Sbjct: 1236 LEKENADLAGELRVLGQAKQEVEHKK---KKLEAQVQELQSKCSDGERARAELNDKVHKL 1292
Query: 186 AMRLAHQS----EEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ + E +G A+ +D+ QL+ + +++ + + + KLR E+R
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 242 PS-QELLWELQQEKALLQARVQELEASVQEGK--LDRSSPYIQVLEEDWRQALRD----- 293
S Q+ L E + K L+ + L + + K L + ++ LEE ++ ++
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412
Query: 294 --HQEQANTIFSLRKDLRQ-------------GEARRLRCMEEKEMFELQCLALRKD-SK 337
++E+A L K + + + + +E+K+ Q LA K+ S
Sbjct: 1413 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISS 1472
Query: 338 MY---KDRIEAILLQMEEVAIER----DQAIATREELH-------AQHARGLQEKDALRK 383
Y +DR EA + E A+ ++A+ +EEL A+ + KD + K
Sbjct: 1473 KYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK 1532
Query: 384 QVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLE 428
V EL + L+ Q+ + + QL +E L+ + L L +++
Sbjct: 1533 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1577
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 61.6 bits (148), Expect = 2e-09
Identities = 81/346 (23%), Positives = 159/346 (45%), Gaps = 31/346 (8%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGS----RE 174
L T + + ++K ++LT L + + I EL V+ K ++ +++LK + E + +
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 175 LKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAED------DCKVER 228
+ + + +L M+LA + EE AAL R D EI Q ++L K + D + +
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDD---EIAQKNNALKKIRELEGHISDLQEDL 1134
Query: 229 KHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWR 288
R+ E++ ++L EL+ K L+ + A+ QE + R + VL++
Sbjct: 1135 DSERAARNKAEKQ-KRDLGEELEALKTELEDTLDST-ATQQELRAKREQE-VTVLKKALD 1191
Query: 289 QALRDHQEQANTIFSLRKDLRQGEARRLRCMEEK-EMFELQCLALRKDSKMYKDRIEAIL 347
+ R H+ Q +++RQ A+ + + E+ E F+ L K+ + + +
Sbjct: 1192 EETRSHEAQV-------QEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1244
Query: 348 LQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVR-ELGEKADELQLQVFQCEAQL 406
++ + + + +++L AQ + LQ K + ++ R EL +K +LQ +V L
Sbjct: 1245 GELRVLGQAKQEVEHKKKKLEAQ-VQELQSKCSDGERARAELNDKVHKLQNEVESVTGML 1303
Query: 407 LAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDK 452
EG+ + + LSS L+D +QEL + + +S K
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQD-----TQELLQEETRQKLNVSTK 1344
Score = 55.1 bits (131), Expect = 1e-07
Identities = 75/315 (23%), Positives = 132/315 (41%), Gaps = 33/315 (10%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEECEAGSRELKRCKE 180
+LQ+++ DL L ++ + L K D LL + + + +E + E + +
Sbjct: 1431 RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKET 1490
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
+ LA L E K N+ L+ E++ L S + K L ME+
Sbjct: 1491 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1550
Query: 241 RPSQELLWELQQEKALLQARVQELEASVQ--EGKLDRSSPYIQVLEEDWRQALRDHQEQA 298
+Q L EL+ E + LE ++Q +G+ +R +Q +E + R Q Q
Sbjct: 1551 MKTQ--LEELEDELQATEDAKLRLEVNMQALKGQFERD---LQARDEQNEEKRRQLQRQL 1605
Query: 299 NTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL------LQMEE 352
+ + +D R+ A ++ E +L+ L L+ DS + K R EAI QM++
Sbjct: 1606 HEYETELEDERKQRALAAAAKKKLEG-DLKDLELQADSAI-KGREEAIKQLRKLQAQMKD 1663
Query: 353 VAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGR 412
E + A A+R+E+ A +E +KA L+ + Q + L A E
Sbjct: 1664 FQRELEDARASRDEIFA--------------TAKENEKKAKSLEADLMQLQEDLAAAERA 1709
Query: 413 LRRQQLETLVLSSDL 427
++ LE L+ +L
Sbjct: 1710 RKQADLEKEELAEEL 1724
Score = 52.8 bits (125), Expect = 7e-07
Identities = 70/328 (21%), Positives = 136/328 (41%), Gaps = 32/328 (9%)
Query: 112 ESGLTQL--LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECE 169
E + QL L ++ Q++++D A S+D+ + + + + + +L+E+
Sbjct: 1648 EEAIKQLRKLQAQMKDFQRELEDARA---SRDEIFATAKENEKKAKSLEADLMQLQEDLA 1704
Query: 170 AGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERK 229
A R K+ E +LA LA + A R L+ I QL+ L + + + +
Sbjct: 1705 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764
Query: 230 HTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQ 289
K EQ L E A ++ Q+ E++ Q+ L+R + ++ +
Sbjct: 1765 RVRKATQQAEQ---------LSNELATERSTAQKNESARQQ--LERQNKELRSKLHEMEG 1813
Query: 290 ALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQ 349
A++ + +TI +L + Q E + + EK+ A K K +++ ILLQ
Sbjct: 1814 AVKSKFK--STIAALEAKIAQLEEQVEQEAREKQ-------AATKSLKQKDKKLKEILLQ 1864
Query: 350 MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAV 409
+E+ ER A +E+ +AR Q L++Q+ E E++ + + + +L
Sbjct: 1865 VED---ERKMAEQYKEQAEKGNARVKQ----LKRQLEEAEEESQRINANRRKLQRELDEA 1917
Query: 410 EGRLRRQQLETLVLSSDLEDGSPRRSQE 437
E L S L P+ + +
Sbjct: 1918 TESNEAMGREVNALKSKLRGPPPQETSQ 1945
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/293 (22%), Positives = 136/293 (46%), Gaps = 28/293 (9%)
Query: 160 RVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMK 219
+V R +EE +A EL++ KE L + E+K + L ++L E ++
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQE-------QLQ 904
Query: 220 AEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPY 279
AE + E + +++R A +++ +E+L E++ AR++E E Q+ + +R
Sbjct: 905 AETELYAEAEE-MRVRLAAKKQELEEILHEME-------ARLEEEEDRGQQLQAERKKMA 956
Query: 280 IQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMY 339
Q+L D + L + +E A L K + + ++L +E + + Q L K+ K+
Sbjct: 957 QQML--DLEEQLEE-EEAARQKLQLEKVTAEAKIKKLE--DEILVMDDQNNKLSKERKLL 1011
Query: 340 KDRIEAI---LLQMEEVAIERDQAIATRE----ELHAQHARGLQEKDALRKQVRELGEKA 392
++RI + L + EE A + E EL + + + + L K R+L A
Sbjct: 1012 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1071
Query: 393 DELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
+ Q+ +AQ+ ++ +L +++ E + L+D +++ L ++LE
Sbjct: 1072 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1124
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/279 (23%), Positives = 132/279 (47%), Gaps = 34/279 (12%)
Query: 127 QKKVQDLTALLSSK-DDFIKELRVK-DSLLRKHQERVQRLKEECEAGSRELKRCKEE--- 181
++K + L A K + +K+L ++ DS ++ +E +++L++ +A ++ +R E+
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK-LQAQMKDFQRELEDARA 1673
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ D A ++E+K + L+ ++ QL+ L AE + ++ L+ E+
Sbjct: 1674 SRDEIFATAKENEKKA------KSLEADLMQLQEDLAAAE---RARKQADLEKEELAEEL 1724
Query: 242 PSQ-ELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
S LQ EK L+AR+ +LE ++E ++ + + R+A + ++ +N
Sbjct: 1725 ASSLSGRNALQDEKRRLEARIAQLEEELEE-----EQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
+ + R ++ E+ R + E Q LR SK++ + A+ + + +
Sbjct: 1780 LATERSTAQKNESAR-------QQLERQNKELR--SKLH-EMEGAVKSKFKSTIAALEAK 1829
Query: 361 IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQV 399
IA EE Q AR EK A K +++ +K E+ LQV
Sbjct: 1830 IAQLEEQVEQEAR---EKQAATKSLKQKDKKLKEILLQV 1865
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/345 (21%), Positives = 147/345 (42%), Gaps = 45/345 (13%)
Query: 126 LQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDL 185
L+K+ DL L +E+ K +K + +VQ L+ +C G R ++ + L
Sbjct: 1236 LEKENADLAGELRVLGQAKQEVEHKK---KKLEAQVQELQSKCSDGERARAELNDKVHKL 1292
Query: 186 AMRLAHQS----EEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ + E +G A+ +D+ QL+ + +++ + + + KLR E+R
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 242 PS-QELLWELQQEKALLQARVQELEASVQEGK--LDRSSPYIQVLEEDWRQALRD----- 293
S Q+ L E + K L+ + L + + K L + ++ LEE ++ ++
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412
Query: 294 --HQEQANTIFSLRKDLRQ-------------GEARRLRCMEEKEMFELQCLALRKD-SK 337
++E+A L K + + + + +E+K+ Q LA K+ S
Sbjct: 1413 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISS 1472
Query: 338 MY---KDRIEAILLQMEEVAIER----DQAIATREELH-------AQHARGLQEKDALRK 383
Y +DR EA + E A+ ++A+ +EEL A+ + KD + K
Sbjct: 1473 KYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK 1532
Query: 384 QVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLE 428
V EL + L+ Q+ + + QL +E L+ + L L +++
Sbjct: 1533 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1577
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 61.6 bits (148), Expect = 2e-09
Identities = 81/346 (23%), Positives = 159/346 (45%), Gaps = 31/346 (8%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGS----RE 174
L T + + ++K ++LT L + + I EL V+ K ++ +++LK + E + +
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 175 LKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAED------DCKVER 228
+ + + +L M+LA + EE AAL R D EI Q ++L K + D + +
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDD---EIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 229 KHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWR 288
R+ E++ ++L EL+ K L+ + A+ QE + R + VL++
Sbjct: 1128 DSERAARNKAEKQ-KRDLGEELEALKTELEDTLDST-ATQQELRAKREQE-VTVLKKALD 1184
Query: 289 QALRDHQEQANTIFSLRKDLRQGEARRLRCMEEK-EMFELQCLALRKDSKMYKDRIEAIL 347
+ R H+ Q +++RQ A+ + + E+ E F+ L K+ + + +
Sbjct: 1185 EETRSHEAQV-------QEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1237
Query: 348 LQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVR-ELGEKADELQLQVFQCEAQL 406
++ + + + +++L AQ + LQ K + ++ R EL +K +LQ +V L
Sbjct: 1238 GELRVLGQAKQEVEHKKKKLEAQ-VQELQSKCSDGERARAELNDKVHKLQNEVESVTGML 1296
Query: 407 LAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDK 452
EG+ + + LSS L+D +QEL + + +S K
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQD-----TQELLQEETRQKLNVSTK 1337
Score = 55.1 bits (131), Expect = 1e-07
Identities = 75/315 (23%), Positives = 132/315 (41%), Gaps = 33/315 (10%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVK----DSLLRKHQERVQRLKEECEAGSRELKRCKE 180
+LQ+++ DL L ++ + L K D LL + + + +E + E + +
Sbjct: 1424 RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKET 1483
Query: 181 ENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQ 240
+ LA L E K N+ L+ E++ L S + K L ME+
Sbjct: 1484 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1543
Query: 241 RPSQELLWELQQEKALLQARVQELEASVQ--EGKLDRSSPYIQVLEEDWRQALRDHQEQA 298
+Q L EL+ E + LE ++Q +G+ +R +Q +E + R Q Q
Sbjct: 1544 MKTQ--LEELEDELQATEDAKLRLEVNMQALKGQFERD---LQARDEQNEEKRRQLQRQL 1598
Query: 299 NTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL------LQMEE 352
+ + +D R+ A ++ E +L+ L L+ DS + K R EAI QM++
Sbjct: 1599 HEYETELEDERKQRALAAAAKKKLEG-DLKDLELQADSAI-KGREEAIKQLRKLQAQMKD 1656
Query: 353 VAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGR 412
E + A A+R+E+ A +E +KA L+ + Q + L A E
Sbjct: 1657 FQRELEDARASRDEIFA--------------TAKENEKKAKSLEADLMQLQEDLAAAERA 1702
Query: 413 LRRQQLETLVLSSDL 427
++ LE L+ +L
Sbjct: 1703 RKQADLEKEELAEEL 1717
Score = 52.8 bits (125), Expect = 7e-07
Identities = 70/328 (21%), Positives = 136/328 (41%), Gaps = 32/328 (9%)
Query: 112 ESGLTQL--LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECE 169
E + QL L ++ Q++++D A S+D+ + + + + + +L+E+
Sbjct: 1641 EEAIKQLRKLQAQMKDFQRELEDARA---SRDEIFATAKENEKKAKSLEADLMQLQEDLA 1697
Query: 170 AGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERK 229
A R K+ E +LA LA + A R L+ I QL+ L + + + +
Sbjct: 1698 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757
Query: 230 HTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQ 289
K EQ L E A ++ Q+ E++ Q+ L+R + ++ +
Sbjct: 1758 RVRKATQQAEQ---------LSNELATERSTAQKNESARQQ--LERQNKELRSKLHEMEG 1806
Query: 290 ALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQ 349
A++ + +TI +L + Q E + + EK+ A K K +++ ILLQ
Sbjct: 1807 AVKSKFK--STIAALEAKIAQLEEQVEQEAREKQ-------AATKSLKQKDKKLKEILLQ 1857
Query: 350 MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAV 409
+E+ ER A +E+ +AR Q L++Q+ E E++ + + + +L
Sbjct: 1858 VED---ERKMAEQYKEQAEKGNARVKQ----LKRQLEEAEEESQRINANRRKLQRELDEA 1910
Query: 410 EGRLRRQQLETLVLSSDLEDGSPRRSQE 437
E L S L P+ + +
Sbjct: 1911 TESNEAMGREVNALKSKLRGPPPQETSQ 1938
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/293 (22%), Positives = 136/293 (46%), Gaps = 28/293 (9%)
Query: 160 RVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMK 219
+V R +EE +A EL++ KE L + E+K + L ++L E ++
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQE-------QLQ 897
Query: 220 AEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPY 279
AE + E + +++R A +++ +E+L E++ AR++E E Q+ + +R
Sbjct: 898 AETELYAEAEE-MRVRLAAKKQELEEILHEME-------ARLEEEEDRGQQLQAERKKMA 949
Query: 280 IQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMY 339
Q+L D + L + +E A L K + + ++L +E + + Q L K+ K+
Sbjct: 950 QQML--DLEEQLEE-EEAARQKLQLEKVTAEAKIKKLE--DEILVMDDQNNKLSKERKLL 1004
Query: 340 KDRIEAI---LLQMEEVAIERDQAIATRE----ELHAQHARGLQEKDALRKQVRELGEKA 392
++RI + L + EE A + E EL + + + + L K R+L A
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1064
Query: 393 DELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLE 445
+ Q+ +AQ+ ++ +L +++ E + L+D +++ L ++LE
Sbjct: 1065 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1117
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/279 (23%), Positives = 132/279 (47%), Gaps = 34/279 (12%)
Query: 127 QKKVQDLTALLSSK-DDFIKELRVK-DSLLRKHQERVQRLKEECEAGSRELKRCKEE--- 181
++K + L A K + +K+L ++ DS ++ +E +++L++ +A ++ +R E+
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK-LQAQMKDFQRELEDARA 1666
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ D A ++E+K + L+ ++ QL+ L AE + ++ L+ E+
Sbjct: 1667 SRDEIFATAKENEKKA------KSLEADLMQLQEDLAAAE---RARKQADLEKEELAEEL 1717
Query: 242 PSQ-ELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANT 300
S LQ EK L+AR+ +LE ++E ++ + + R+A + ++ +N
Sbjct: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELEE-----EQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 301 IFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQA 360
+ + R ++ E+ R + E Q LR SK++ + A+ + + +
Sbjct: 1773 LATERSTAQKNESAR-------QQLERQNKELR--SKLH-EMEGAVKSKFKSTIAALEAK 1822
Query: 361 IATREELHAQHARGLQEKDALRKQVRELGEKADELQLQV 399
IA EE Q AR EK A K +++ +K E+ LQV
Sbjct: 1823 IAQLEEQVEQEAR---EKQAATKSLKQKDKKLKEILLQV 1858
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/345 (21%), Positives = 147/345 (42%), Gaps = 45/345 (13%)
Query: 126 LQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDL 185
L+K+ DL L +E+ K +K + +VQ L+ +C G R ++ + L
Sbjct: 1229 LEKENADLAGELRVLGQAKQEVEHKK---KKLEAQVQELQSKCSDGERARAELNDKVHKL 1285
Query: 186 AMRLAHQS----EEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQR 241
+ + E +G A+ +D+ QL+ + +++ + + + KLR E+R
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 242 PS-QELLWELQQEKALLQARVQELEASVQEGK--LDRSSPYIQVLEEDWRQALRD----- 293
S Q+ L E + K L+ + L + + K L + ++ LEE ++ ++
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Query: 294 --HQEQANTIFSLRKDLRQ-------------GEARRLRCMEEKEMFELQCLALRKD-SK 337
++E+A L K + + + + +E+K+ Q LA K+ S
Sbjct: 1406 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISS 1465
Query: 338 MY---KDRIEAILLQMEEVAIER----DQAIATREELH-------AQHARGLQEKDALRK 383
Y +DR EA + E A+ ++A+ +EEL A+ + KD + K
Sbjct: 1466 KYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK 1525
Query: 384 QVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLE 428
V EL + L+ Q+ + + QL +E L+ + L L +++
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 61.6 bits (148), Expect = 2e-09
Identities = 78/349 (22%), Positives = 146/349 (41%), Gaps = 32/349 (9%)
Query: 118 LLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKR 177
+L+ E LQ ++Q L L S +EL ++ ++H R+Q K E +EL R
Sbjct: 989 MLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVLEIQGQELHR 1048
Query: 178 CKEENYDLAMRLAHQSEEKG--------------AALMRNRDLQLEIDQLKHSLMKAEDD 223
K E + +R A QS+E+ A L R ++ +LE ++H +KA
Sbjct: 1049 -KLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAELEGLLVRHRDLKAN-- 1105
Query: 224 CKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVL 283
L+L H Q ++L + +A A + E E +Q+G R L
Sbjct: 1106 -----MRALELAHRELQGRHEQLQAQRASVEAQEVALLAERERLMQDGHRQRG------L 1154
Query: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343
EE+ R+ +H + L ++ + + R EL+ L S+ ++
Sbjct: 1155 EEELRRLQSEHDRAQMLLAELSRERGELQGERGELRGRLARLELERAQLEMQSQQLRESN 1214
Query: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403
+ + L + + + R ++ + L E AL ++ REL E++ E + + + +
Sbjct: 1215 QQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHREQ 1274
Query: 404 AQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSDK 452
+ L LRR++ + + D R + + LP+ + + L+DK
Sbjct: 1275 REYLDQLNALRREKQKLVEKIMD----QYRVLEPVPLPRTKKGSWLADK 1319
Score = 48.9 bits (115), Expect = 1e-05
Identities = 71/294 (24%), Positives = 135/294 (45%), Gaps = 29/294 (9%)
Query: 145 KELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAH-QSEEKGAALMRN 203
+ ++V +S R+H E +R + E EA EL++ +L RL H Q E + AAL R
Sbjct: 844 ERMQVLESEGRQHLEEAERERREKEALQAELEKAVVRGKELGARLEHLQRELEQAALERQ 903
Query: 204 RDL-QLEIDQLKHSLMKAEDDCKVERKHTLKLRHAMEQRPS----QELLWELQQEKALL- 257
L + E ++ ++ + +++ T K ME + +E L++L+Q A L
Sbjct: 904 EFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLG 963
Query: 258 ---QARVQELEA-SVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDL----R 309
+A Q +E +V+ +++RS+ + + + L+ + Q ++ ++L +
Sbjct: 964 PKKRAEPQLVETQNVRLIEVERSNAMLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQ 1023
Query: 310 QGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEV-----AIERD-QAIAT 363
+ + R EK + E+Q L + ++ ++ + A EE A+ RD +A+A
Sbjct: 1024 RAQEHSSRLQAEKSVLEIQGQELHRKLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQ 1083
Query: 364 REELHAQHARGL--QEKD------ALRKQVRELGEKADELQLQVFQCEAQLLAV 409
+ GL + +D AL REL + ++LQ Q EAQ +A+
Sbjct: 1084 LQRRQEAELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRASVEAQEVAL 1137
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/177 (24%), Positives = 83/177 (46%), Gaps = 11/177 (6%)
Query: 230 HTLKLRHAMEQRPSQELLWELQQEKALL---QARVQELEASVQEGKLDRSSPYIQVLEED 286
H L L+ A + + L EL+++ LL QA VQ LEA ++ + + + Q +
Sbjct: 254 HHLALQLANAKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLRQEAQALSGQAKRAE 313
Query: 287 -WRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCL---ALRKDSKMYKDR 342
+R+ +E+A + L+++LR+ R K E + + L + +++
Sbjct: 314 LYREEAEALRERAGRLPRLQEELRRCRERLQAAEAYKSQLEEERVLSGVLEASKALLEEQ 373
Query: 343 IEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQV 399
+EA + + + + + R L HA E D+LR QV +L E+ EL+L++
Sbjct: 374 LEAARERCARLHETQRENLLLRTRLGEAHA----ELDSLRHQVDQLAEENVELELEL 426
Score = 38.9 bits (89), Expect = 0.011
Identities = 51/229 (22%), Positives = 98/229 (42%), Gaps = 10/229 (4%)
Query: 226 VERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQE---LEASVQEGKLDRSSPYIQV 282
V + L+ A +R ++ L EL+ + L+A+ E L + + + + + +
Sbjct: 724 VAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREA 783
Query: 283 LEEDWRQA-LRDHQEQANTIFSLRKDLRQGEARRLRCM-EEKEMFELQCLALRKDSKMYK 340
+ W QA LR+ E A R+ L E+ +E + LR S+ +
Sbjct: 784 EAQAWEQARLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAE 843
Query: 341 DRIEAILLQ----MEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQ 396
+R++ + + +EE ER + A + EL RG + L REL + A E Q
Sbjct: 844 ERMQVLESEGRQHLEEAERERREKEALQAELEKAVVRGKELGARLEHLQRELEQAALERQ 903
Query: 397 LQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDG-SPRRSQELSLPQDL 444
+ + E+Q +G +R + E ++ E+ +++ L L ++L
Sbjct: 904 EFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEEL 952
Score = 30.0 bits (66), Expect = 5.0
Identities = 27/111 (24%), Positives = 45/111 (40%), Gaps = 1/111 (0%)
Query: 306 KDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERDQAIATRE 365
+ L G A + EE + AL + + ++EA + ++ E QA
Sbjct: 718 ESLASGVAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEA 777
Query: 366 ELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQ 416
E H + E+ LR+ V G++ + Q + + LA GR RRQ
Sbjct: 778 EAHREAEAQAWEQARLREAVEAAGQELESAS-QEREALVEALAAAGRERRQ 827
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 60.8 bits (146), Expect = 3e-09
Identities = 84/386 (21%), Positives = 158/386 (40%), Gaps = 49/386 (12%)
Query: 89 QLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDD----FI 144
Q K+ KE + + D S + + K+ + ++D + L +K++ I
Sbjct: 1214 QRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLI 1273
Query: 145 KELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNR 204
+L + + L+ R +E +A +L R K+ + L HQ EE+ A
Sbjct: 1274 NDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAK---- 1329
Query: 205 DLQLEIDQLKHSLMKAEDDCKV-------ERKHTLKLRHAMEQRPSQELLW--------- 248
+ L H+L + DC + E++ +L+ A+ + S+ W
Sbjct: 1330 ------NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1383
Query: 249 ----ELQQEKALLQARVQELEASVQ--EGKLDRSSPYIQVLEEDWRQALRDHQEQANTIF 302
EL++ K L R+QE E V+ K Q L+ + + D +
Sbjct: 1384 QRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACA 1443
Query: 303 SLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMY-------KDRIEAILLQMEEVAI 355
+L K R + ++ E + + A +K+S+ K+ E L Q+E +
Sbjct: 1444 ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR 1503
Query: 356 ER---DQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGR 412
E Q I+ E A+ + + E + ++KQV + EK E+Q + + EA L EG+
Sbjct: 1504 ENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQ--EKC-EIQAALEEAEASLEHEEGK 1560
Query: 413 LRRQQLETLVLSSDLEDGSPRRSQEL 438
+ R QLE + S+++ + +E+
Sbjct: 1561 ILRIQLELNQVKSEVDRKIAEKDEEI 1586
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/335 (21%), Positives = 140/335 (41%), Gaps = 41/335 (12%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
E+ L K++D A+ IKEL Q R++ L EE EA + +++
Sbjct: 1089 EISNLISKIEDEQAVEIQLQKKIKEL----------QARIEELGEEIEAERASRAKAEKQ 1138
Query: 182 NYDLAMRL---AHQSEEKGAA----LMRNRDLQLEIDQLKHSLMKAEDD-----CKVERK 229
DL+ L + + EE G A + N+ + E +L+ L +A + +K
Sbjct: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198
Query: 230 HTLKLRHAMEQRPS-QELLWELQQEKALLQARVQELEASVQ-----EGKLDRSSPYIQVL 283
H + EQ + Q + +L++EK+ L+ +L ++ + +G L++ ++
Sbjct: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQ 1258
Query: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343
+ + + Q N + + R L+ R ++EK+ Q L + + +I
Sbjct: 1259 VSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQ---LSRSKQASTQQI 1315
Query: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403
E + Q+EE + A HA + + D LR+Q E E ELQ + +
Sbjct: 1316 EELKHQLEE------ETKAKNALAHALQS-SRHDCDLLREQYEEEQEGKAELQRALSKAN 1368
Query: 404 AQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQEL 438
++ V + + + + + +LE+ + +Q L
Sbjct: 1369 SE---VAQWRTKYETDAIQRTEELEEAKKKLAQRL 1400
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/389 (23%), Positives = 159/389 (40%), Gaps = 71/389 (18%)
Query: 119 LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRC 178
L E +L+K + DL L+ + KE ++ ++ E + L E S+E K
Sbjct: 946 LEDECSELKKDIDDLELTLAKVE---KEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002
Query: 179 KEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSL--------------MKAEDDC 224
+E + L + ++ L+ ++D L+ SL K E D
Sbjct: 1003 QETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1062
Query: 225 KVERKHTLKLRHAMEQRPSQ---------ELLWELQQEKAL----------LQARVQELE 265
K+ ++ T+ + + +Q + L+ +++ E+A+ LQAR++EL
Sbjct: 1063 KLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELG 1122
Query: 266 ASVQEGKLDRS------SPYIQVLEEDWRQALRDHQEQANTIFSLRKDL---RQGEARRL 316
++ + R+ S + LEE + + E+A S + +L R+ E ++L
Sbjct: 1123 EEIEAERASRAKAEKQRSDLSRELEE-----ISERLEEAGGATSAQVELNKKREAEFQKL 1177
Query: 317 -RCMEEKEM-FELQCLALRK---DSKM----YKDRIEAILLQME----EVAIERDQAIAT 363
R +EE + E ALRK DS D ++ + ++E E+ +E D +
Sbjct: 1178 RRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSN 1237
Query: 364 REELHAQHARGLQEK--DALRKQVRELGEKADELQLQVFQCEAQ---LLAVEGRLRRQQL 418
E + A+G EK +L QV EL K +E Q + AQ L G RQ
Sbjct: 1238 AEAI--SKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLD 1295
Query: 419 ETLVLSSDLEDGSPRRSQEL-SLPQDLED 446
E L S L +Q++ L LE+
Sbjct: 1296 EKDALVSQLSRSKQASTQQIEELKHQLEE 1324
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/301 (20%), Positives = 128/301 (42%), Gaps = 44/301 (14%)
Query: 158 QERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNR-DLQLEIDQLKHS 216
++ + +KEE + EL + + + +L EEK L++ + DLQL++ S
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKEL--------EEKMVTLLKEKNDLQLQVQSEADS 900
Query: 217 LMKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQEL-EASVQEGKLDR 275
L AE+ C+ +L + K L+A+++E+ E + +E +++
Sbjct: 901 LADAEERCE-----------------------QLIKNKIQLEAKIKEVTERAEEEEEINA 937
Query: 276 S-SPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRK 334
+ + LE++ + +D + T+ + K+ E + EE + L K
Sbjct: 938 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSK 997
Query: 335 DSKMYKDRIEAIL--LQMEEVAIERDQAIATREELHAQHARG-LQEKDALRKQVRELGEK 391
+ K ++ + L LQ EE + T+ E G L+++ LR + K
Sbjct: 998 EKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRK 1057
Query: 392 AD-ELQL---QVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDT 447
+ +L+L E ++ +L +++ E L S +ED ++ E+ L + +++
Sbjct: 1058 LEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIED---EQAVEIQLQKKIKEL 1114
Query: 448 Q 448
Q
Sbjct: 1115 Q 1115
Score = 38.9 bits (89), Expect = 0.011
Identities = 79/359 (22%), Positives = 139/359 (38%), Gaps = 70/359 (19%)
Query: 112 ESGLTQL--LMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECE 169
E L QL L E LQ+++ DLT ++ I EL + + + +Q EE E
Sbjct: 1492 EESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAE 1551
Query: 170 AGSR-----------ELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQ--LKHS 216
A EL + K E + ++A + EE L RN +E Q L
Sbjct: 1552 ASLEHEEGKILRIQLELNQVKSE---VDRKIAEKDEEIDQ-LKRNHTRVVETMQSTLDAE 1607
Query: 217 LMKAEDDCKVERKHT-------LKLRHA--------MEQRPSQELLWELQ---------- 251
+ D +V++K ++L HA R +Q +L E Q
Sbjct: 1608 IRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQ 1667
Query: 252 -----------QEKALLQARVQELEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQA-- 298
+ LLQA ++EL A++++ + R ++L+ R L Q +
Sbjct: 1668 EDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLI 1727
Query: 299 NTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQMEEVAIERD 358
NT L D+ Q ++ ++E R + K I + EE+ E+D
Sbjct: 1728 NTKKKLENDVSQLQSEVEEVIQES----------RNAEEKAKKAITDAAMMAEELKKEQD 1777
Query: 359 QAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQ 417
+ A E + + +++ + +L K + Q+Q + EA++ +EG + +Q
Sbjct: 1778 TS-AHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ--KLEARVRELEGEVENEQ 1833
Score = 38.5 bits (88), Expect = 0.014
Identities = 69/343 (20%), Positives = 140/343 (40%), Gaps = 28/343 (8%)
Query: 109 ASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQ---ERVQRLK 165
A + + QL ++ L A + S++D ++ + + L + + RL
Sbjct: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639
Query: 166 EECEAGSRELKRCKEE---NYDLAMRLAHQSEEKGAALMRNRDL-QLEIDQLKHSLMKAE 221
E R + +E + D A+R +E+ A + R +L Q EI++L +L + E
Sbjct: 1640 AESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTE 1699
Query: 222 DDCKVERKHTLKLRHAMEQRPSQELLW-----ELQQEKALLQARVQEL--EASVQEGKLD 274
K+ + L ++ +Q +L+ + + LQ+ V+E+ E+ E K
Sbjct: 1700 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAK 1759
Query: 275 RSSPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRK 334
++ ++ E+ L+ Q+ + + ++K+L Q ++E E L K
Sbjct: 1760 KAITDAAMMAEE----LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL------K 1809
Query: 335 DSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQE----KDALRKQVRELGE 390
K ++EA + ++E + A + +H R ++E + RK V L +
Sbjct: 1810 GGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQD 1869
Query: 391 KADELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPR 433
D+LQ +V + Q E + + L +LE+ R
Sbjct: 1870 LVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEER 1912
Score = 34.7 bits (78), Expect = 0.20
Identities = 36/157 (22%), Positives = 69/157 (43%), Gaps = 15/157 (9%)
Query: 125 KLQKKVQDLTALLSSKDDFIKELRVKDSL--LRKHQERVQRLKEECEAGSRELKRCKEEN 182
+++K ++ L + D ++L +K ++K + RV+ L+ E E E KR E
Sbjct: 1784 RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE---NEQKRNAEAV 1840
Query: 183 YDL------AMRLAHQSEEKGAALMRNRDL----QLEIDQLKHSLMKAEDDCKVERKHTL 232
L L +Q+EE ++R +DL Q ++ K +AE+
Sbjct: 1841 KGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFR 1900
Query: 233 KLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQ 269
KL+H +E+ + + E Q K +++R + S +
Sbjct: 1901 KLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 31.2 bits (69), Expect = 2.2
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 17/114 (14%)
Query: 122 EVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEE 181
EV QK+ + L + +KEL + RK+ R+Q L ++ +A + KR EE
Sbjct: 1828 EVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEE 1887
Query: 182 NYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLMKAEDDCKVERKHTLKLR 235
E+ A L + R LQ H L +AE+ + KLR
Sbjct: 1888 ----------AEEQSNANLSKFRKLQ-------HELEEAEERADIAESQVNKLR 1924
Score = 30.4 bits (67), Expect = 3.8
Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 13/150 (8%)
Query: 305 RKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAIL---LQMEEVAIERDQAI 361
RK+L E + + ++EK +LQ + ++R E ++ +Q+E E +
Sbjct: 873 RKEL---EEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERA 929
Query: 362 ATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLETL 421
EE++A+ +K L + EL + D+L+L + + E + A E +++ E
Sbjct: 930 EEEEEINAELTA---KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE-- 984
Query: 422 VLSSDLEDGSPRRSQELSLPQDLEDTQLSD 451
+ L++ + S+E Q+ L D
Sbjct: 985 --MAGLDETIAKLSKEKKALQETHQQTLDD 1012
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,457,260
Number of Sequences: 37866
Number of extensions: 857227
Number of successful extensions: 7769
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 758
Number of HSP's that attempted gapping in prelim test: 4441
Number of HSP's gapped (non-prelim): 2623
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.