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Search of human proteins with 16507200
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16507200 ubiquitin specific protease 28 [Homo sapiens]
(1077 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16507200 ubiquitin specific protease 28 [Homo sapiens] 2157 0.0
gi|50312666 ubiquitin specific peptidase 25 [Homo sapiens] 994 0.0
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 84 9e-16
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 84 9e-16
gi|110347427 ubiquitin specific protease 34 [Homo sapiens] 65 4e-10
gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [... 62 4e-09
gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [... 62 4e-09
gi|188497648 ubiquitin specific peptidase 37 [Homo sapiens] 60 1e-08
gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] 58 4e-08
gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens] 57 7e-08
gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] 57 9e-08
gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens] 57 9e-08
gi|149192845 ubiquitin specific protease 24 [Homo sapiens] 57 1e-07
gi|71774197 ubiquitin specific protease 47 [Homo sapiens] 55 3e-07
gi|148746183 ubiquitin specific protease 35 [Homo sapiens] 55 4e-07
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 50 9e-06
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 50 9e-06
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 50 1e-05
gi|32313610 ubiquitin specific protease 18 [Homo sapiens] 49 3e-05
gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens] 47 7e-05
gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo sap... 47 7e-05
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 47 7e-05
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 47 1e-04
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 47 1e-04
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 47 1e-04
gi|13994268 ubiquitin-specific protease 26 [Homo sapiens] 46 2e-04
gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 46 2e-04
gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 45 3e-04
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 45 3e-04
gi|10190742 ubiquitin specific peptidase 29 [Homo sapiens] 45 5e-04
>gi|16507200 ubiquitin specific protease 28 [Homo sapiens]
Length = 1077
Score = 2157 bits (5589), Expect = 0.0
Identities = 1077/1077 (100%), Positives = 1077/1077 (100%)
Query: 1 MTAELQQDDAAGAADGHGSSCQMLLNQLREITGIQDPSFLHEALKASNGDITQAVSLLTD 60
MTAELQQDDAAGAADGHGSSCQMLLNQLREITGIQDPSFLHEALKASNGDITQAVSLLTD
Sbjct: 1 MTAELQQDDAAGAADGHGSSCQMLLNQLREITGIQDPSFLHEALKASNGDITQAVSLLTD 60
Query: 61 ERVKEPSQDTVATEPSEVEGSAANKEVLAKVIDLTHDNKDDLQAAIALSLLESPKIQADG 120
ERVKEPSQDTVATEPSEVEGSAANKEVLAKVIDLTHDNKDDLQAAIALSLLESPKIQADG
Sbjct: 61 ERVKEPSQDTVATEPSEVEGSAANKEVLAKVIDLTHDNKDDLQAAIALSLLESPKIQADG 120
Query: 121 RDLNRMHEATSAETKRSKRKRCEVWGENPNPNDWRRVDGWPVGLKNVGNTCWFSAVIQSL 180
RDLNRMHEATSAETKRSKRKRCEVWGENPNPNDWRRVDGWPVGLKNVGNTCWFSAVIQSL
Sbjct: 121 RDLNRMHEATSAETKRSKRKRCEVWGENPNPNDWRRVDGWPVGLKNVGNTCWFSAVIQSL 180
Query: 181 FQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAALD 240
FQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAALD
Sbjct: 181 FQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAALD 240
Query: 241 LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEG 300
LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEG
Sbjct: 241 LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEG 300
Query: 301 VREGKPFCNNETFGQYPLQVNGYRNLDECLEGAMVEGDVELLPSDHSVKYGQERWFTKLP 360
VREGKPFCNNETFGQYPLQVNGYRNLDECLEGAMVEGDVELLPSDHSVKYGQERWFTKLP
Sbjct: 301 VREGKPFCNNETFGQYPLQVNGYRNLDECLEGAMVEGDVELLPSDHSVKYGQERWFTKLP 360
Query: 361 PVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRNKRECIRKLKEEIK 420
PVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRNKRECIRKLKEEIK
Sbjct: 361 PVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRNKRECIRKLKEEIK 420
Query: 421 ILQQKLERYVKYGSGPARFPLPDMLKYVIEFASTKPASESCPPESDTHMTLPLSSVHCSV 480
ILQQKLERYVKYGSGPARFPLPDMLKYVIEFASTKPASESCPPESDTHMTLPLSSVHCSV
Sbjct: 421 ILQQKLERYVKYGSGPARFPLPDMLKYVIEFASTKPASESCPPESDTHMTLPLSSVHCSV 480
Query: 481 SDQTSKESTSTESSSQDVESTFSSPEDSLPKSKPLTSSRSSMEMPSQPAPRTVTDEEINF 540
SDQTSKESTSTESSSQDVESTFSSPEDSLPKSKPLTSSRSSMEMPSQPAPRTVTDEEINF
Sbjct: 481 SDQTSKESTSTESSSQDVESTFSSPEDSLPKSKPLTSSRSSMEMPSQPAPRTVTDEEINF 540
Query: 541 VKTCLQRWRSEIEQDIQDLKTCIASTTQTIEQMYCDPLLRQVPYRLHAVLVHEGQANAGH 600
VKTCLQRWRSEIEQDIQDLKTCIASTTQTIEQMYCDPLLRQVPYRLHAVLVHEGQANAGH
Sbjct: 541 VKTCLQRWRSEIEQDIQDLKTCIASTTQTIEQMYCDPLLRQVPYRLHAVLVHEGQANAGH 600
Query: 601 YWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSAYCLMYINDKLPYFNAEAA 660
YWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSAYCLMYINDKLPYFNAEAA
Sbjct: 601 YWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSAYCLMYINDKLPYFNAEAA 660
Query: 661 PTESDQMSEVEALSVELKHYIQEDNWRFEQEVEEWEEEQSCKIPQMESSTNSSSQDYSTS 720
PTESDQMSEVEALSVELKHYIQEDNWRFEQEVEEWEEEQSCKIPQMESSTNSSSQDYSTS
Sbjct: 661 PTESDQMSEVEALSVELKHYIQEDNWRFEQEVEEWEEEQSCKIPQMESSTNSSSQDYSTS 720
Query: 721 QEPSVASSHGVRCLSSEHAVIVKEQTAQAIANTARAYEKSGVEAALSEVMLSPAMQGVIL 780
QEPSVASSHGVRCLSSEHAVIVKEQTAQAIANTARAYEKSGVEAALSEVMLSPAMQGVIL
Sbjct: 721 QEPSVASSHGVRCLSSEHAVIVKEQTAQAIANTARAYEKSGVEAALSEVMLSPAMQGVIL 780
Query: 781 AIAKARQTFDRDGSEAGLIKAFHEEYSRLYQLAKETPTSHSDPRLQHVLVYFFQNEAPKR 840
AIAKARQTFDRDGSEAGLIKAFHEEYSRLYQLAKETPTSHSDPRLQHVLVYFFQNEAPKR
Sbjct: 781 AIAKARQTFDRDGSEAGLIKAFHEEYSRLYQLAKETPTSHSDPRLQHVLVYFFQNEAPKR 840
Query: 841 VVERTLLEQFADKNLSYDERSISIMKVAQAKLKEIGPDDMNMEEYKKWHEDYSLFRKVSV 900
VVERTLLEQFADKNLSYDERSISIMKVAQAKLKEIGPDDMNMEEYKKWHEDYSLFRKVSV
Sbjct: 841 VVERTLLEQFADKNLSYDERSISIMKVAQAKLKEIGPDDMNMEEYKKWHEDYSLFRKVSV 900
Query: 901 YLLTGLELYQKGKYQEALSYLVYAYQSNAALLMKGPRRGVKESVIALYRRKCLLELNAKA 960
YLLTGLELYQKGKYQEALSYLVYAYQSNAALLMKGPRRGVKESVIALYRRKCLLELNAKA
Sbjct: 901 YLLTGLELYQKGKYQEALSYLVYAYQSNAALLMKGPRRGVKESVIALYRRKCLLELNAKA 960
Query: 961 ASLFETNDDHSVTEGINVMNELIIPCIHLIINNDISKDDLDAIEVMRNHWCSYLGQDIAE 1020
ASLFETNDDHSVTEGINVMNELIIPCIHLIINNDISKDDLDAIEVMRNHWCSYLGQDIAE
Sbjct: 961 ASLFETNDDHSVTEGINVMNELIIPCIHLIINNDISKDDLDAIEVMRNHWCSYLGQDIAE 1020
Query: 1021 NLQLCLGEFLPRLLDPSAEIIVLKEPPTIRPNSPYDLCSRFAAVMESIQGVSTVTVK 1077
NLQLCLGEFLPRLLDPSAEIIVLKEPPTIRPNSPYDLCSRFAAVMESIQGVSTVTVK
Sbjct: 1021 NLQLCLGEFLPRLLDPSAEIIVLKEPPTIRPNSPYDLCSRFAAVMESIQGVSTVTVK 1077
>gi|50312666 ubiquitin specific peptidase 25 [Homo sapiens]
Length = 1055
Score = 994 bits (2569), Expect = 0.0
Identities = 525/1067 (49%), Positives = 716/1067 (67%), Gaps = 57/1067 (5%)
Query: 22 QMLLNQLREITGIQDPSFLHEALKASNGDITQAVSLLTDERVKEPSQDTVATEPSEVEGS 81
Q LNQLREITGI D L +ALK SNG++ AV+ LT + K P Q+ + + G+
Sbjct: 18 QTFLNQLREITGINDTQILQQALKDSNGNLELAVAFLTAKNAKTPQQEETTYYQTALPGN 77
Query: 82 ----AANKEVLAKVIDLTHDNKDDLQAAIALSLLESPK------IQADGRDLNRMHEATS 131
+ + VIDLT D+KDDLQ AIALSL ES + I + + ++R+ EA+
Sbjct: 78 DRYISVGSQADTNVIDLTGDDKDDLQRAIALSLAESNRAFRETGITDEEQAISRVLEASI 137
Query: 132 AETKRS-KRKRCEVWGENPNPNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLV 190
AE K KR EVW ++ NP D +R D PVGLKNVGNTCWFSAVIQSLF L EFRRLV
Sbjct: 138 AENKACLKRTPTEVWRDSRNPYDRKRQDKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLV 197
Query: 191 LSYSLPQNVLENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRSSE 250
L+Y P N + R+ E RN+ FM+EL+YLFAL++G+ RK+VDPS A+++LK AF+S++
Sbjct: 198 LNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRAVEILKDAFKSND 257
Query: 251 EQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNN 310
QQQDVSEFTHKLLDWLEDAFQ+ + K +NPMV+LFYG FL GV EGK F N
Sbjct: 258 SQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAVGVLEGKKFENT 317
Query: 311 ETFGQYPLQVNGYRNLDECLEGAMVEGDVELLPSDHSVKYGQERWFTKLPPVLTFELSRF 370
E FGQYPLQVNG+++L ECLE AM+EG++E L S++S K GQE WFT+LPPVLTFELSRF
Sbjct: 318 EMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSENSGKSGQEHWFTELPPVLTFELSRF 377
Query: 371 EFNQSLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRNKRECIRKLKEEIKILQQKLERYV 430
EFNQ+LG+PEKIHNKLEFPQ++Y+DRYM+R++E+ R KRE I++LK+ + +LQQ+LERY+
Sbjct: 378 EFNQALGRPEKIHNKLEFPQVLYLDRYMHRNREITRIKREEIKRLKDYLTVLQQRLERYL 437
Query: 431 KYGSGPARFPLPDMLKYVIEFASTKPASESCPPESDTHMTLPLSSVHCSVSDQTSKESTS 490
YGSGP RFPL D+L+Y +EFAS+KP S P D + P S S+ QT +T
Sbjct: 438 SYGSGPKRFPLVDVLQYALEFASSKPVCTS--PVDDIDASSPPSG---SIPSQTLPSTTE 492
Query: 491 TESS-SQDVESTFSSPEDSLPKS----KPLTSSRSSMEMPSQPAPRTVTDEEINFVKTCL 545
+ + S ++ ST S ++ KP T SR ++P PAPR +T+EE++ +++CL
Sbjct: 493 QQGALSSELPSTSPSSVAAISSRSVIHKPFTQSRIPPDLPMHPAPRHITEEELSVLESCL 552
Query: 546 QRWRSEIEQDIQDLKTCIASTTQTIEQMYCDPLLRQVPYRLHAVLVHEGQANAGHYWAYI 605
RWR+EIE D +DL+ I+ +TIE MY D + QVPYRLHAVLVHEGQANAGHYWAYI
Sbjct: 553 HRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEGQANAGHYWAYI 612
Query: 606 YNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSAYCLMYINDKLPYFNAEAAPTESD 665
++ W+KYNDI+VT+SSWEE+ RDS+GG RN SAYCLMYINDK + E E+
Sbjct: 613 FDHRESRWMKYNDIAVTKSSWEELVRDSFGGYRNASAYCLMYINDKAQFLIQEEFNKETG 672
Query: 666 Q-MSEVEALSVELKHYIQEDNWRFEQEVEEWEEEQSCKIPQMESSTNSSSQDYSTSQEPS 724
Q + +E L +L+ +++EDN RFE+E+EEW+ + + K Q + + ++ TS +
Sbjct: 673 QPLVGIETLPPDLRDFVEEDNQRFEKELEEWDAQLAQKALQEKLLASQKLRESETSVTTA 732
Query: 725 VASS---HGVRCLSSEHAVIVKEQTAQAIANTARAYEKSGVEAALSEVMLSPAMQGVILA 781
A+ + + S+ + +KE+T Q I + +E E L
Sbjct: 733 QAAGDPEYLEQPSRSDFSKHLKEETIQIITKASHEHEDKSPETVLQS------------- 779
Query: 782 IAKARQTFDRDGSEAGLIKAFHEEYSRLYQLAKETPTSHSDPRLQHVLVYFFQNEAPKRV 841
A EY+RL +LA+E +D RL HV+VYF QN+APK++
Sbjct: 780 -------------------AIKLEYARLVKLAQEDTPPETDYRLHHVVVYFIQNQAPKKI 820
Query: 842 VERTLLEQFADKNLSYDERSISIMKVAQAKLKEIGPDDMNMEEYKKWHEDYSLFRKVSVY 901
+E+TLLEQF D+NLS+DER +IMKVAQAKL+ I P+++N+EEY++WH+DY FR+ ++Y
Sbjct: 821 IEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVNLEEYEEWHQDYRKFRETTMY 880
Query: 902 LLTGLELYQKGKYQEALSYLVYAYQSNAALLMKGPRRGVKESVIALYRRKCLLELNAKAA 961
L+ GLE +Q+ Y ++L +L+ AYQ+N LL KG RG E +I+ YRR+CLL+LN +AA
Sbjct: 881 LIIGLENFQRESYIDSLLFLICAYQNNKELLSKGLYRGHDEELISHYRRECLLKLNEQAA 940
Query: 962 SLFETNDDHSVTEGINVMNELIIPCIHLIINNDISKDDLDAIEVMRNHWCSYLGQDIAEN 1021
LFE+ +D V G+ +MNE I+P + L++ +++ + D+ A+E MRN WCSYLGQ++ +
Sbjct: 941 ELFESGEDREVNNGLIIMNEFIVPFLPLLLVDEMEEKDILAVEDMRNRWCSYLGQEMEPH 1000
Query: 1022 LQLCLGEFLPRLLDPSAEIIVLKEPPTIRPNSPYDLCSRFAAVMESI 1068
LQ L +FLP+LLD S EI EPP + S ++LC RFA +M S+
Sbjct: 1001 LQEKLTDFLPKLLDCSMEIKSFHEPPKLPSYSTHELCERFARIMLSL 1047
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 83.6 bits (205), Expect = 9e-16
Identities = 73/262 (27%), Positives = 113/262 (43%), Gaps = 24/262 (9%)
Query: 150 NPNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVL-------SYSLPQNVLEN 202
+PN RR VGL N+G TC+ + +Q F E R+ + Y L + E
Sbjct: 77 DPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEE 136
Query: 203 CRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHK 262
E + I + LQYLFAL+ SNR+++DPS + A QQQD EF+
Sbjct: 137 --KDYEPQTIC--EHLQYLFALLQNSNRRYIDPSGFVK----ALGLDTGQQQDAQEFSKL 188
Query: 263 LLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNG 322
+ LED N + + + Y T + RE K F + L + G
Sbjct: 189 FMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLL---SKFYELELNIQG 245
Query: 323 YRNLDEC----LEGAMVEGDVELLPSDHSVKYGQER--WFTKLPPVLTFELSRFEFNQSL 376
++ L +C L+ +EGD + K R LP L +L RF F++
Sbjct: 246 HKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQT 305
Query: 377 GQPEKIHNKLEFPQIIYMDRYM 398
G +K++ + F +I+ M+ Y+
Sbjct: 306 GHKKKLNTYIGFSEILDMEPYV 327
Score = 36.6 bits (83), Expect = 0.13
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 584 YRLHAVLVHEG-QANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVE 630
Y L AVL+H G A +GHY A++ + W K+ND + + ++++
Sbjct: 336 YELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQ 383
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 83.6 bits (205), Expect = 9e-16
Identities = 73/262 (27%), Positives = 113/262 (43%), Gaps = 24/262 (9%)
Query: 150 NPNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVL-------SYSLPQNVLEN 202
+PN RR VGL N+G TC+ + +Q F E R+ + Y L + E
Sbjct: 77 DPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEE 136
Query: 203 CRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHK 262
E + I + LQYLFAL+ SNR+++DPS + A QQQD EF+
Sbjct: 137 --KDYEPQTIC--EHLQYLFALLQNSNRRYIDPSGFVK----ALGLDTGQQQDAQEFSKL 188
Query: 263 LLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNG 322
+ LED N + + + Y T + RE K F + L + G
Sbjct: 189 FMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLL---SKFYELELNIQG 245
Query: 323 YRNLDEC----LEGAMVEGDVELLPSDHSVKYGQER--WFTKLPPVLTFELSRFEFNQSL 376
++ L +C L+ +EGD + K R LP L +L RF F++
Sbjct: 246 HKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQT 305
Query: 377 GQPEKIHNKLEFPQIIYMDRYM 398
G +K++ + F +I+ M+ Y+
Sbjct: 306 GHKKKLNTYIGFSEILDMEPYV 327
Score = 36.6 bits (83), Expect = 0.13
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 584 YRLHAVLVHEG-QANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVE 630
Y L AVL+H G A +GHY A++ + W K+ND + + ++++
Sbjct: 336 YELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQ 383
>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
Length = 3546
Score = 64.7 bits (156), Expect = 4e-10
Identities = 76/289 (26%), Positives = 118/289 (40%), Gaps = 51/289 (17%)
Query: 151 PNDWRRVDGWP----------VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVL 200
P W D WP VGL N+G TC+ ++ IQ L+ +PE R+ V + +++
Sbjct: 1876 PYKW---DYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDM- 1931
Query: 201 ENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDP---SAALDLLKGAFRSSEEQQQDVS 257
++ + ELQ +F +M S K +P + K + E Q+D++
Sbjct: 1932 ---------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGE--QKDMT 1980
Query: 258 EFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNN--ETFGQ 315
EF L+ +E+ SP K N + LF G V + E F
Sbjct: 1981 EFFTDLITKIEEM--------SPELK--NTVKSLFGGVITNNVVSLDCEHVSQTAEEFYT 2030
Query: 316 YPLQV----NGYRNLDECLEGAMVEGDVELLPSDH---SVKYGQERWFTKLPPVLTFELS 368
QV N Y +LDE +EGD + H V+ + F KLP +L+F
Sbjct: 2031 VRCQVADMKNIYESLDEVTIKDTLEGD-NMYTCSHCGKKVRAEKRACFKKLPRILSFNTM 2089
Query: 369 RFEFNQSLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRNKRECIRKLKE 417
R+ FN EK++ FP + M Y +++ + K E KE
Sbjct: 2090 RYTFNMVTMMKEKVNTHFSFPLRLDMTPY---TEDFLMGKSERKEGFKE 2135
Score = 40.8 bits (94), Expect = 0.007
Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 20/131 (15%)
Query: 584 YRLHAVLVHEGQANAGHYWAYI------YNQPRQSWLKYNDISVTESSWEEVERDSYGGL 637
Y L V VH G A+ GHY+++I + W +ND V ++ + +GG
Sbjct: 2148 YDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGE 2207
Query: 638 RNVSAYCLMYINDKLPYFNAEAA------------PTESDQMSEVEALSVELKHYIQEDN 685
Y + DK F+ E P E + +S EL +I DN
Sbjct: 2208 MTTKTY--DSVTDKFMDFSFEKTHSAYMLFYKRMEPEEENGREYKFDVSSELLEWIWHDN 2265
Query: 686 WRFEQEVEEWE 696
+F Q+ +E
Sbjct: 2266 MQFLQDKNIFE 2276
>gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [Homo
sapiens]
Length = 2554
Score = 61.6 bits (148), Expect = 4e-09
Identities = 69/280 (24%), Positives = 120/280 (42%), Gaps = 53/280 (18%)
Query: 162 VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLS----------------------------- 192
VGLKN G TC+ ++VIQ L+ +P R +L+
Sbjct: 1557 VGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDD 1616
Query: 193 -YSLPQNVLEN-CRSHTEKR---NIMFMQELQYLFALMMGSNRKFVDPSAALDLLK-GAF 246
+ PQ + S TE R NI ++ LQ +F + S ++ P +
Sbjct: 1617 VFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGE 1676
Query: 247 RSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKP 306
+ +Q D EF + L+D L++A + + P S+ + G+F + + +G P
Sbjct: 1677 PVNLREQHDALEFFNSLVDSLDEALKA---LGHPAMLSK-----VLGGSFADQKICQGCP 1728
Query: 307 --FCNNETFGQYPLQVNGYRNLDECLEGAMVEGDV-ELLPSDHSVKYGQE------RWFT 357
+ E+F + + ++NL + LE V+GD+ E + H K ++
Sbjct: 1729 HRYECEESFTTLNVDIRNHQNLLDSLE-QYVKGDLLEGANAYHCEKCNKKVDTVKRLLIK 1787
Query: 358 KLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRY 397
KLPPVL +L RF+++ K ++ EFP+ + M+ Y
Sbjct: 1788 KLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPY 1827
Score = 49.3 bits (116), Expect = 2e-05
Identities = 26/61 (42%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
Query: 584 YRLHAVLVHEGQANAGHYWAYIYNQ-----PRQSWLKYNDISVTESSW---EEVERDSYG 635
YRL VLVH GQA+ GHY++YI + R W K++D VTE EE++ +G
Sbjct: 1863 YRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKNQCFG 1922
Query: 636 G 636
G
Sbjct: 1923 G 1923
>gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [Homo
sapiens]
Length = 2570
Score = 61.6 bits (148), Expect = 4e-09
Identities = 69/280 (24%), Positives = 120/280 (42%), Gaps = 53/280 (18%)
Query: 162 VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLS----------------------------- 192
VGLKN G TC+ ++VIQ L+ +P R +L+
Sbjct: 1557 VGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDD 1616
Query: 193 -YSLPQNVLEN-CRSHTEKR---NIMFMQELQYLFALMMGSNRKFVDPSAALDLLK-GAF 246
+ PQ + S TE R NI ++ LQ +F + S ++ P +
Sbjct: 1617 VFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGE 1676
Query: 247 RSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKP 306
+ +Q D EF + L+D L++A + + P S+ + G+F + + +G P
Sbjct: 1677 PVNLREQHDALEFFNSLVDSLDEALKA---LGHPAMLSK-----VLGGSFADQKICQGCP 1728
Query: 307 --FCNNETFGQYPLQVNGYRNLDECLEGAMVEGDV-ELLPSDHSVKYGQE------RWFT 357
+ E+F + + ++NL + LE V+GD+ E + H K ++
Sbjct: 1729 HRYECEESFTTLNVDIRNHQNLLDSLE-QYVKGDLLEGANAYHCEKCNKKVDTVKRLLIK 1787
Query: 358 KLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRY 397
KLPPVL +L RF+++ K ++ EFP+ + M+ Y
Sbjct: 1788 KLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPY 1827
Score = 49.3 bits (116), Expect = 2e-05
Identities = 26/61 (42%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
Query: 584 YRLHAVLVHEGQANAGHYWAYIYNQ-----PRQSWLKYNDISVTESSW---EEVERDSYG 635
YRL VLVH GQA+ GHY++YI + R W K++D VTE EE++ +G
Sbjct: 1863 YRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKNQCFG 1922
Query: 636 G 636
G
Sbjct: 1923 G 1923
>gi|188497648 ubiquitin specific peptidase 37 [Homo sapiens]
Length = 979
Score = 60.1 bits (144), Expect = 1e-08
Identities = 129/642 (20%), Positives = 224/642 (34%), Gaps = 182/642 (28%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLF 222
G N+GNTC+ +A++QSLF L F +L +P + + L F
Sbjct: 342 GFSNLGNTCYMNAILQSLFSLQSFANDLLKQGIPWKKIP-------------LNALIRRF 388
Query: 223 ALMMGSNRKFVDPSAALDLLKG--------AFRSSEEQQQDVSEFTHKLLDWLEDAFQLA 274
A ++ + + DLLK A R S Q D EF + LD L++ +
Sbjct: 389 AHLL-VKKDICNSETKKDLLKKVKNAISATAERFSGYMQNDAHEFLSQCLDQLKEDMEKL 447
Query: 275 VN------VNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNGYRNLD- 327
V+ N + + + +T E + + G+ + + +L
Sbjct: 448 NKTWKTEPVSGEENSPDISATRAYTCPVITNLEFEVQHSIICKACGEIIPKREQFNDLSI 507
Query: 328 ------ECLEGAMVEGDVELLPSDHSVKYGQERW----------FTKLPPVLTFELSRFE 371
+ L ++ ++L ++Y E+ F +LP VL L R+
Sbjct: 508 DLPRRKKPLPPRSIQDSLDLFFRAEELEYSCEKCGGKCALVRHKFNRLPRVLILHLKRYS 567
Query: 372 FNQSLGQPEKIHNKLEFPQIIYMDRY------------------MYRSKELIRNKRECIR 413
FN +L KI ++ P+ + + + + R + + CI
Sbjct: 568 FNVALSLNNKIGQQVIIPRYLTLSSHCTENTKPPFTLGWSAHMAISRPLKASQMVNSCIT 627
Query: 414 -----------KLKEEIKIL-----QQKLERYVKYGSGPARFPLPDMLKYVIEFASTKPA 457
K K + + + +L+R V L +ML + +
Sbjct: 628 SPSTPSKKFTFKSKSSLALCLDSDSEDELKRSVALSQR-----LCEMLGNEQQQEDLEKD 682
Query: 458 SESCPPESDTHMTLPLSSVHCSVSDQTSKE---STSTESSSQDVESTFSSPEDSLPKSKP 514
S+ CP E D S + S D+ S+E + E S +D + S +D P S P
Sbjct: 683 SKLCPIEPDK------SELENSGFDRMSEEELLAAVLEISKRDASPSLSHEDDDKPTSSP 736
Query: 515 LTSSRSS--MEMPSQP------APRTVTDEE----INFVKTC------------------ 544
T EMP P P+T+T+ + K C
Sbjct: 737 DTGFAEDDIQEMPENPDTMETEKPKTITELDPASFTEITKDCDENKENKTPEGSQGEVDW 796
Query: 545 LQRWRSEIEQDIQDLKTCIASTTQ---TIEQMYCDPLLRQVP------------------ 583
LQ++ E E++ Q+L+ +A + Q EQ D L R
Sbjct: 797 LQQYDMEREREEQELQQALAQSLQEQEAWEQKEDDDLKRATELSLQEFNNSFVDALGSDE 856
Query: 584 --------------------------------YRLHAVLVHEGQ-ANAGHYWAYIYNQPR 610
YRL +V+ H G +++GHY + +Y+ +
Sbjct: 857 DSGNEDVFDMEYTEAEAEELKRNAETGNLPHSYRLISVVSHIGSTSSSGHYISDVYDIKK 916
Query: 611 QSWLKYNDISVTESSWEEVERDSYGGLRNVSAYCLMYINDKL 652
Q+W YND+ V++ V+ D R+ S Y Y++ ++
Sbjct: 917 QAWFTYNDLEVSKIQEAAVQSD-----RDRSGYIFFYMHKEI 953
>gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]
Length = 1247
Score = 58.2 bits (139), Expect = 4e-08
Identities = 63/262 (24%), Positives = 109/262 (41%), Gaps = 23/262 (8%)
Query: 122 DLNRMHEATSAETKRSKRKRCEVWG-ENPNPNDWRRVDGWPVGLKNVGNTCWFSAVIQSL 180
DL +T + + K K+ + E P P ++ + G ++N G TC+ ++++Q+L
Sbjct: 16 DLFEEEYSTVSNNQYGKGKKLKTKALEPPAPREFTNLSG----IRNQGGTCYLNSLLQTL 71
Query: 181 FQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAALD 240
PEFR + S + L + + + + +LQ LFA ++ +++ + D
Sbjct: 72 HFTPEFREALFSLGPEELGLFEDKDKPDAKVRIIPLQLQRLFAQLLLLDQEAASTADLTD 131
Query: 241 LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEG 300
G + E +Q DV E L LE + + + +L++GT + +
Sbjct: 132 SF-GWTSNEEMRQHDVQELNRILFSALETSL--------VGTSGHDLIYRLYHGTIVNQI 182
Query: 301 V-REGKPFC-NNETFGQYPLQVNGYRNLDECLEGAMVEGDV-------ELLPSDHSVKYG 351
V +E K E F + V L++ L VE +V D VK
Sbjct: 183 VCKECKNVSERQEDFLDLTVAVKNVSGLEDALWNMYVEEEVFDCDNLYHCGTCDRLVKAA 242
Query: 352 QERWFTKLPPVLTFELSRFEFN 373
+ KLPP LT L RF F+
Sbjct: 243 KSAKLRKLPPFLTVSLLRFNFD 264
>gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens]
Length = 1042
Score = 57.4 bits (137), Expect = 7e-08
Identities = 38/107 (35%), Positives = 57/107 (53%), Gaps = 14/107 (13%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLF 222
GL N+GNTC+ ++VIQ+LF +FRR VLS + L C S M++LQ+LF
Sbjct: 446 GLINLGNTCYMNSVIQALFMATDFRRQVLSLN-----LNGCNS--------LMKKLQHLF 492
Query: 223 ALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLED 269
A + + R+ P + + + + QQD SE+ LLD L +
Sbjct: 493 AFLAHTQREAYAPRIFFEASRPPW-FTPRSQQDCSEYLRFLLDRLHE 538
Score = 33.5 bits (75), Expect = 1.1
Identities = 46/221 (20%), Positives = 80/221 (36%), Gaps = 52/221 (23%)
Query: 519 RSSMEMPSQPAPRTVTDEEINFVKTCLQRWRSEIEQDIQDLKTCIASTTQT--IEQMYCD 576
R ++ S P + + I + + W ++ D DL +A + ++ C
Sbjct: 778 RKILDNVSLPLVLELPVKRITSFSSLSESW--SVDVDFTDLSENLAKKLKPSGTDEASCT 835
Query: 577 PLLRQVPYRLHAVLVHEG-QANAGHYWAYIYN---------------------------- 607
L VPY L +V+VH G + +GHY++Y N
Sbjct: 836 KL---VPYLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHLLG 892
Query: 608 ---------------QPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSAYCLMYINDKL 652
+ + W +ND VT +S++ V++ + +AY L+Y
Sbjct: 893 RDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKIT-SRFPKDTAYVLLYKKQHS 951
Query: 653 PYFNAEAAPTESDQMSEVEALSVELKHYIQEDNWRFEQEVE 693
+ PT ++ L EL I +DN + QE E
Sbjct: 952 TNGLSGNNPTSGLWINGDPPLQKELMDAITKDNKLYLQEQE 992
>gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]
Length = 1102
Score = 57.0 bits (136), Expect = 9e-08
Identities = 60/249 (24%), Positives = 113/249 (45%), Gaps = 31/249 (12%)
Query: 162 VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYL 221
VGLKN G TC+ ++++Q+LF + R+ V Y +P ++ +S LQ +
Sbjct: 214 VGLKNQGATCYMNSLLQTLFFTNQLRKAV--YMMPTEGDDSSKS--------VPLALQRV 263
Query: 222 FALMMGSNRKFVDPSAALDLLK--GAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNS 279
F + S++ P L K G Q DV E LLD +E+ +
Sbjct: 264 FYELQHSDK----PVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTC---- 315
Query: 280 PRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQ--VNGYRNLDECLEGAM--- 334
E + +LF G ++ + + ++ Y +Q + G +N+ E +
Sbjct: 316 ----VEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVE 371
Query: 335 -VEGDVELLPSDHSVKYGQERW-FTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQII 392
++GD + +H ++ ++ F LPPVL +L RF ++ Q KI+++ EFP+ +
Sbjct: 372 QLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQL 431
Query: 393 YMDRYMYRS 401
+D ++ ++
Sbjct: 432 PLDEFLQKT 440
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/148 (29%), Positives = 64/148 (43%), Gaps = 17/148 (11%)
Query: 571 EQMYCDPLLRQVP------YRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTES 624
EQ+ D L++ Y LHAVLVH G + GHY Y+ + W K++D V+
Sbjct: 429 EQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRC 488
Query: 625 SWEEVERDSYGGLRN-------VSAYCLMYINDKLPYFNAEAAPTESDQMSEVEALSVEL 677
+ EE +YGG + +AY L+YI + +A VE L E
Sbjct: 489 TKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEK 548
Query: 678 KHYIQEDNWRFE----QEVEEWEEEQSC 701
+ Q+ R E +V+ E+Q C
Sbjct: 549 RIEAQKRKERQEAHLYMQVQIVAEDQFC 576
>gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]
Length = 2555
Score = 57.0 bits (136), Expect = 9e-08
Identities = 66/279 (23%), Positives = 114/279 (40%), Gaps = 51/279 (18%)
Query: 162 VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLS----------------------------- 192
VGLKN G TC+ ++VIQ L+ +P R +L+
Sbjct: 1559 VGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDD 1618
Query: 193 -YSLPQNVLEN-CRSHTEKR---NIMFMQELQYLFALMMGSNRKFVDPSAALDLLK-GAF 246
+ P + S TE R NI ++ LQ +F + S ++ P +
Sbjct: 1619 VFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGE 1678
Query: 247 RSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKP 306
+ +Q D EF + L+D L++A + + P S+ + G+F + + +G P
Sbjct: 1679 PVNLREQHDALEFFNSLVDSLDEALKA---LGHPAILSK-----VLGGSFADQKICQGCP 1730
Query: 307 --FCNNETFGQYPLQVNGYRNLDECLE----GAMVEGD--VELLPSDHSVKYGQERWFTK 358
+ E+F + + ++NL + LE G ++EG D V + K
Sbjct: 1731 HRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKK 1790
Query: 359 LPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRY 397
LP VL +L RF+++ K ++ EFP+ + M Y
Sbjct: 1791 LPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPY 1829
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 8/61 (13%)
Query: 584 YRLHAVLVHEGQANAGHYWAYIY-----NQPRQSWLKYNDISVTESSW---EEVERDSYG 635
YRL VLVH GQA+ GHY++YI + W K++D VTE EE++ +G
Sbjct: 1865 YRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKNQCFG 1924
Query: 636 G 636
G
Sbjct: 1925 G 1925
>gi|149192845 ubiquitin specific protease 24 [Homo sapiens]
Length = 2460
Score = 56.6 bits (135), Expect = 1e-07
Identities = 65/263 (24%), Positives = 112/263 (42%), Gaps = 42/263 (15%)
Query: 151 PNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKR 210
P D R G+ VGL+N G TC+ +AV Q L+ P LP+++L + T+
Sbjct: 1519 PVDSRSSSGF-VGLRNGGATCYMNAVFQQLYMQP---------GLPESLL-SVDDDTDNP 1567
Query: 211 NIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRS-SEEQQQDVSEFTHKLLDWLED 269
+ ++Q LF +M S ++ P + K + +QQD EF L+D +++
Sbjct: 1568 DDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDE 1627
Query: 270 AFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNN--------ETFGQYPLQVN 321
+ + Q+F TF +G+ + C + E F L V
Sbjct: 1628 YLK------------KMGRDQIFKNTF--QGIYSDQKICKDCPHRYEREEAFMALNLGVT 1673
Query: 322 GYRNLDECLEGAMVEGDVELLPSDHSVKYGQERWFT-------KLPPVLTFELSRFEFNQ 374
++L+ L+ V G+V + + + +E+ T LP VL L RF F+
Sbjct: 1674 SCQSLEISLD-QFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDW 1732
Query: 375 SLGQPEKIHNKLEFPQIIYMDRY 397
G+ K ++ FP ++ M+ Y
Sbjct: 1733 ESGRSIKYDEQIRFPWMLNMEPY 1755
Score = 44.3 bits (103), Expect = 6e-04
Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 7/81 (8%)
Query: 584 YRLHAVLVHEGQANAGHYWAYIYNQ---PRQSWLKYNDISVTESSW--EEVERDSYGGLR 638
Y L V+VH GQA+AGHY+++I ++ + W K+ND + E E +E + +GG
Sbjct: 1794 YELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEY 1853
Query: 639 NVSAY--CLMYINDKLPYFNA 657
Y Y + + Y+NA
Sbjct: 1854 RPKVYDQTNPYTDVRRRYWNA 1874
Score = 38.1 bits (87), Expect = 0.045
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 33 GIQDPSFLHEALKASNGDITQAVSLLTDERVKEPSQDTVATEPSEVEGSAANKEVLAKVI 92
G DP+ + +AL+ + DI +AV+LLT+ER P D EP + G + + E + +
Sbjct: 8 GFSDPATIRKALRLAKNDINEAVALLTNER---PGLDYGGYEPMDSGGLSESDENCRRFM 64
Query: 93 D 93
D
Sbjct: 65 D 65
>gi|71774197 ubiquitin specific protease 47 [Homo sapiens]
Length = 1287
Score = 55.5 bits (132), Expect = 3e-07
Identities = 56/255 (21%), Positives = 113/255 (44%), Gaps = 39/255 (15%)
Query: 162 VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYL 221
VGL N TC+ ++++Q+LF PEFR + + ++ + S +LQ L
Sbjct: 100 VGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTS--------IPYQLQRL 151
Query: 222 FALMMGSNRKFVDPSAALDLLKGAFRSSEE--QQQDVSEFTHKLLDWLEDAFQLAVNVNS 279
F L+ S ++ ++ + D+ + S E QQ DV E + D LE +
Sbjct: 152 FVLLQTSKKRAIETT---DVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKW-------- 200
Query: 280 PRNKSENPMVQLFYGTFLTEGVR---EGKPFCNNETFGQYPLQVNGY------RNLDECL 330
+ + ++ Y L + VR G +T+ PL + Y +++E L
Sbjct: 201 -KQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEAL 259
Query: 331 EGAMVEGDVELLPSDHSVKYGQERW-------FTKLPPVLTFELSRFEFNQSLGQPEKIH 383
A ++ ++ P+ + + +++ F P +LT +L RF+F+ + K++
Sbjct: 260 H-AFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLN 318
Query: 384 NKLEFPQIIYMDRYM 398
+++ FP+ + M ++
Sbjct: 319 DRMTFPEELDMSTFI 333
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Query: 584 YRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSAY 643
Y L +V+VH G A GHY+A I + + W +ND V+ + E++++ G + Y
Sbjct: 399 YELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYY 458
Query: 644 CLMYINDKLPYFNAEAA--PTESDQMSEVEALSVELKHYIQEDNWRFEQEVEEWE-EEQS 700
+ + Y P + + EV+ +K+ +Q++ EQE + E E +
Sbjct: 459 SSAFASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNT 518
Query: 701 CKI 703
CKI
Sbjct: 519 CKI 521
>gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
Length = 1018
Score = 55.1 bits (131), Expect = 4e-07
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 14/137 (10%)
Query: 151 PNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKR 210
P + D +GL N+GNTC+ ++++Q+LF +FR VL TE
Sbjct: 430 PRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRL-------------TENN 476
Query: 211 NIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLEDA 270
+ M +LQ+LF + S R + P L + S QQD SE+ LLD L +
Sbjct: 477 SQPLMTKLQWLFGFLEHSQRPAISPENFLSASWTPW-FSPGTQQDCSEYLKYLLDRLHEE 535
Query: 271 FQLAVNVNSPRNKSENP 287
+ + +S +P
Sbjct: 536 EKTGTRICQKLKQSSSP 552
Score = 38.5 bits (88), Expect = 0.035
Identities = 42/157 (26%), Positives = 65/157 (41%), Gaps = 28/157 (17%)
Query: 577 PLLRQVP--------YRLHAVLVHEG-QANAGHYWAYIYN---------------QPRQS 612
PLL ++P Y L +V+VH G + +GHY+ Y +P
Sbjct: 830 PLLLRLPLAGGRGQAYDLCSVVVHSGVSSESGHYYCYAREGAARPAASLGTADRPEPENQ 889
Query: 613 WLKYNDISVTESSWEEVERDSYGGLRNVSAYCLMYINDKLPYFNAEAAPTESDQMSEVEA 672
W +ND V+ SS+E V + +AY L Y + P EA S +E
Sbjct: 890 WYLFNDTRVSFSSFESVSNVT-SFFPKDTAYVLFY--RQRPREGPEAELGSSRVRTE-PT 945
Query: 673 LSVELKHYIQEDNWRFEQEVEEWEEEQSCKIPQMESS 709
L +L I +DN + QE E+ ++ I + +S
Sbjct: 946 LHKDLMEAISKDNILYLQEQEKEARSRAAYISALPTS 982
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
sapiens]
Length = 359
Score = 50.4 bits (119), Expect = 9e-06
Identities = 67/256 (26%), Positives = 102/256 (39%), Gaps = 43/256 (16%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLF 222
GL N GNTC+ ++V+Q+L+ FR VL+Y Q EN + L LF
Sbjct: 29 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKEN-----------LLTCLADLF 77
Query: 223 ALMMGSNRK--FVDPSAALD-LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAV---- 275
+ +K + P + L K QQD EF + LL+ + D Q
Sbjct: 78 HSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEK 137
Query: 276 --------NVNSP--RNKSENPMV-QLFYGTFLTEG--VREGKPFCNNETFGQYPLQVNG 322
N+N P NK E V ++F GT E + +E F + V
Sbjct: 138 QNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQ 197
Query: 323 YRNLDECLEGAMVEGDVELLPSDH--------SVKYGQERW-FTKLPPVLTFELSRFEFN 373
++ CL + E L S+ S + Q+R KLP +L L RF++
Sbjct: 198 NTSITHCLRDF---SNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYM 254
Query: 374 QSLGQPEKIHNKLEFP 389
+ L + K+ ++ FP
Sbjct: 255 EQLHRYTKLSYRVVFP 270
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
Length = 366
Score = 50.4 bits (119), Expect = 9e-06
Identities = 67/256 (26%), Positives = 102/256 (39%), Gaps = 43/256 (16%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLF 222
GL N GNTC+ ++V+Q+L+ FR VL+Y Q EN + L LF
Sbjct: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKEN-----------LLTCLADLF 84
Query: 223 ALMMGSNRK--FVDPSAALD-LLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAV---- 275
+ +K + P + L K QQD EF + LL+ + D Q
Sbjct: 85 HSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEK 144
Query: 276 --------NVNSP--RNKSENPMV-QLFYGTFLTEG--VREGKPFCNNETFGQYPLQVNG 322
N+N P NK E V ++F GT E + +E F + V
Sbjct: 145 QNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQ 204
Query: 323 YRNLDECLEGAMVEGDVELLPSDH--------SVKYGQERW-FTKLPPVLTFELSRFEFN 373
++ CL + E L S+ S + Q+R KLP +L L RF++
Sbjct: 205 NTSITHCLRDF---SNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYM 261
Query: 374 QSLGQPEKIHNKLEFP 389
+ L + K+ ++ FP
Sbjct: 262 EQLHRYTKLSYRVVFP 277
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 49.7 bits (117), Expect = 1e-05
Identities = 76/278 (27%), Positives = 104/278 (37%), Gaps = 57/278 (20%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRS------HTEKR---NIM 213
GL+N+GNTC+ +A++QSL + +F LP L N ++ HT + N+
Sbjct: 160 GLRNLGNTCFMNAILQSLSNIEQF--CCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVS 217
Query: 214 FMQEL-QYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQ 272
++E + L AL GS F S + K QQQD EF LLD L Q
Sbjct: 218 LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
Query: 273 LAVN------------VNSPRNK----SENPMVQLFYGTFLTEGV---------REGKPF 307
N S NK + +V +G L V R+ PF
Sbjct: 278 GGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPF 337
Query: 308 CNNETFGQYPLQVNGYR----------NLDECLEG--AMVEGDVELLPSDHSVKYGQER- 354
+ P Q R +L +CL + E D L H K Q+
Sbjct: 338 LDLSL--DIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKST 395
Query: 355 ---WFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFP 389
W KLP VL L RF + L K+ +EFP
Sbjct: 396 KKFWIQKLPKVLCLHLKRFHWTAYL--RNKVDTYVEFP 431
>gi|32313610 ubiquitin specific protease 18 [Homo sapiens]
Length = 372
Score = 48.9 bits (115), Expect = 3e-05
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
Query: 584 YRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLR---NV 640
Y L AV+ H G A++GHY YI N W +ND ++ SWE+++ +YG
Sbjct: 302 YELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQ-CTYGNPNYHWQE 360
Query: 641 SAYCLMYI 648
+AY L+Y+
Sbjct: 361 TAYLLVYM 368
Score = 35.8 bits (81), Expect = 0.22
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 11/106 (10%)
Query: 132 AETKRSKRKRCEVWGENPN--PNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRL 189
A+ + K + + E P P W G VGL N+G TC +++IQ +F R+
Sbjct: 24 ADLEEKKEEDSNMKREQPRERPRAWDYPHGL-VGLHNIGQTCCLNSLIQVFVMNVDFTRI 82
Query: 190 VLSYSLPQNVLENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDP 235
+ ++P+ E ++R++ F ++ L M S +K V P
Sbjct: 83 LKRITVPRGADE------QRRSVPF--QMLLLLEKMQDSRQKAVRP 120
>gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens]
Length = 822
Score = 47.4 bits (111), Expect = 7e-05
Identities = 53/203 (26%), Positives = 90/203 (44%), Gaps = 28/203 (13%)
Query: 76 SEVEGSAANKEVLAKVIDLTHDNKDDLQAAIALSLLESPKIQADGRDLNRMHEATSAETK 135
+EV+ ++N+ L +V+D QA+I +PK + D ++ ++ E+K
Sbjct: 121 NEVQYCSSNQ--LGQVVDYVRK-----QASIT-----TPKPEKDNGNIELENKKLEKESK 168
Query: 136 --RSKRKRCEVWGENPNPNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSY 193
+ + K+ + ENP N ++ GL N+GNTC+F+AV+Q+L Q P R L+
Sbjct: 169 NEQEREKKENMAKENPPMNSPCQIT--VKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEV 226
Query: 194 SLPQNVL----------ENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAAL-DLL 242
+ ++ E + E + + Q+L M + + V P +
Sbjct: 227 KMSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNE-MQETKKGVVTPKELFSQVC 285
Query: 243 KGAFRSSEEQQQDVSEFTHKLLD 265
K A R QQQD E LLD
Sbjct: 286 KKAVRFKGYQQQDSQELLRYLLD 308
>gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo
sapiens]
Length = 347
Score = 47.4 bits (111), Expect = 7e-05
Identities = 19/47 (40%), Positives = 28/47 (59%)
Query: 584 YRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVE 630
Y L AV+ H G A++GHY YI N W +ND ++ SWE+++
Sbjct: 291 YELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQ 337
Score = 34.3 bits (77), Expect = 0.65
Identities = 57/261 (21%), Positives = 101/261 (38%), Gaps = 23/261 (8%)
Query: 151 PNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKR 210
P W G VGL N+G TC +++IQ +F R++ ++P+ E ++R
Sbjct: 34 PRSWDYRHGL-VGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADE------QRR 86
Query: 211 NIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLEDA 270
++ F ++ L M S +K V P L+ + Q D ++ KL + ++D
Sbjct: 87 SVPF--QMLLLLEKMQDSRQKAVWPLELAYCLQ-KYNVPLFVQHDAAQLYLKLWNLIKD- 142
Query: 271 FQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNET--FGQYPLQVNGYRNLDE 328
Q+A +V+ M+++ + E + T + + + L++
Sbjct: 143 -QIA-DVHLVERLQALYMIRMKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLED 200
Query: 329 CLEGAMVEGDVELLPSDHSVKYG------QERWFTKLPPVLTFELSRFEFNQSLGQPEKI 382
L ++ G Q T LP LT L RF S Q KI
Sbjct: 201 ALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS--QTRKI 258
Query: 383 HNKLEFPQIIYMDRYMYRSKE 403
+ L FPQ + + + +E
Sbjct: 259 CHSLYFPQSLDFSQILPMKRE 279
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 47.4 bits (111), Expect = 7e-05
Identities = 63/254 (24%), Positives = 97/254 (38%), Gaps = 21/254 (8%)
Query: 154 WRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIM 213
W RV GL N+GNTC+ +A IQ L P +LS E+ RS + M
Sbjct: 114 WERVFRVGAGLHNLGNTCFLNATIQCLTYTPPLANYLLS-------KEHARSCHQGSFCM 166
Query: 214 FMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQL 273
++ S S DL K A Q+D EF +D ++ A L
Sbjct: 167 LCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKAC-L 225
Query: 274 AVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQY---PLQVNGYRNLDECL 330
R +V +G +L V+ ++T+ Y L++ N+ L
Sbjct: 226 NGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRAL 285
Query: 331 E----GAMVEGDVELLPSDHSVKYGQERWFT--KLPPVLTFELSRFEFNQSLGQPEKIHN 384
E ++ G+ + + K + FT + VLT L RF N S G KI
Sbjct: 286 ELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFA-NFSGG---KITK 341
Query: 385 KLEFPQIIYMDRYM 398
+ +P+ + + YM
Sbjct: 342 DVGYPEFLNIRPYM 355
Score = 37.4 bits (85), Expect = 0.077
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 10/68 (14%)
Query: 582 VPYRLHAVLVHEG-QANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNV 640
V Y L+AVLVH G +AGHY+ Y+ Q W + ND V S+ + V N
Sbjct: 363 VMYGLYAVLVHSGYSCHAGHYYCYVKASNGQ-WYQMNDSLVHSSNVKVV--------LNQ 413
Query: 641 SAYCLMYI 648
AY L Y+
Sbjct: 414 QAYVLFYL 421
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 46.6 bits (109), Expect = 1e-04
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 8/66 (12%)
Query: 582 VPYRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVS 641
V Y L +V+ H G A++GHY AY N W +++D SVTE S V+ N
Sbjct: 647 VTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQ--------NAE 698
Query: 642 AYCLMY 647
AY L Y
Sbjct: 699 AYVLFY 704
Score = 38.1 bits (87), Expect = 0.045
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 13/110 (11%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLF 222
GLKN+GNTC+ +A +Q+L P + L + T+K+ + L+ +
Sbjct: 186 GLKNIGNTCYMNAALQALSNCPPLTQFFLDC--------GGLARTDKKPAICKSYLKLMT 237
Query: 223 ALMMGSNRKFVDPSAALDLLK---GAFRSSEEQQQDVSEFTHKLLDWLED 269
L S V P+ +K FR QQD EF L+D L +
Sbjct: 238 ELWHKSRPGSVVPTTLFQGIKTVNPTFRG--YSQQDAQEFLRCLMDLLHE 285
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 46.6 bits (109), Expect = 1e-04
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 8/66 (12%)
Query: 582 VPYRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVS 641
V Y L +V+ H G A++GHY AY N W +++D SVTE S V+ N
Sbjct: 655 VTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQ--------NAE 706
Query: 642 AYCLMY 647
AY L Y
Sbjct: 707 AYVLFY 712
Score = 38.1 bits (87), Expect = 0.045
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 13/110 (11%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLF 222
GLKN+GNTC+ +A +Q+L P + L + T+K+ + L+ +
Sbjct: 186 GLKNIGNTCYMNAALQALSNCPPLTQFFLDC--------GGLARTDKKPAICKSYLKLMT 237
Query: 223 ALMMGSNRKFVDPSAALDLLK---GAFRSSEEQQQDVSEFTHKLLDWLED 269
L S V P+ +K FR QQD EF L+D L +
Sbjct: 238 ELWHKSRPGSVVPTTLFQGIKTVNPTFRG--YSQQDAQEFLRCLMDLLHE 285
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 46.6 bits (109), Expect = 1e-04
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 8/66 (12%)
Query: 582 VPYRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVS 641
V Y L +V+ H G A++GHY AY N W +++D SVTE S V+ N
Sbjct: 624 VTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQ--------NAE 675
Query: 642 AYCLMY 647
AY L Y
Sbjct: 676 AYVLFY 681
Score = 38.1 bits (87), Expect = 0.045
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 13/110 (11%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLF 222
GLKN+GNTC+ +A +Q+L P + L + T+K+ + L+ +
Sbjct: 155 GLKNIGNTCYMNAALQALSNCPPLTQFFLDC--------GGLARTDKKPAICKSYLKLMT 206
Query: 223 ALMMGSNRKFVDPSAALDLLK---GAFRSSEEQQQDVSEFTHKLLDWLED 269
L S V P+ +K FR QQD EF L+D L +
Sbjct: 207 ELWHKSRPGSVVPTTLFQGIKTVNPTFRG--YSQQDAQEFLRCLMDLLHE 254
>gi|13994268 ubiquitin-specific protease 26 [Homo sapiens]
Length = 913
Score = 46.2 bits (108), Expect = 2e-04
Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 16/126 (12%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYS-----LPQNVLENCRSHTEKRNIMFMQE 217
GL N+GNTC+ +AV+QSL +P F +L+ S +P N L C + R + F
Sbjct: 296 GLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLA----RLLFFKDT 351
Query: 218 LQYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNV 277
M+ N K SAA ++ G Q D EF LD L+D + +
Sbjct: 352 YNIEIKEMLLLNLKKA-ISAAAEIFHG------NAQNDAHEFLAHCLDQLKDNMEKLNTI 404
Query: 278 NSPRNK 283
P+++
Sbjct: 405 WKPKSE 410
Score = 35.0 bits (79), Expect = 0.38
Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
Query: 584 YRLHAVLVHEGQA-NAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSA 642
YRL +V+ H G+ +GHY Y+ +Q W Y+D+ V +++ D R +
Sbjct: 824 YRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQED-----RRCTG 878
Query: 643 YCLMYINDKL 652
Y Y+++++
Sbjct: 879 YIFFYMHNEI 888
>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
Length = 1604
Score = 45.8 bits (107), Expect = 2e-04
Identities = 74/337 (21%), Positives = 128/337 (37%), Gaps = 31/337 (9%)
Query: 358 KLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQ--------IIYMDRYMYRSKELIRNKR 409
+LPP+L L RF+F G+ K ++FP+ ++ D + + K L
Sbjct: 1273 RLPPILIIHLKRFQFVN--GRWIKSQKIVKFPRESFDPSAFLVPRDPALCQHKPLTPQGD 1330
Query: 410 ECI--RKLKEEIKILQQKL---ERYVKYGSGPARFPLPDMLKYVIEFASTKPASESCPPE 464
E R L E+K + + E V P+ + +S++ + SCP
Sbjct: 1331 ELSEPRILAREVKKVDAQSSAGEEDVLLSKSPSSLSANIISSPKGSPSSSRKSGTSCPSS 1390
Query: 465 SDTHMTLPLSSVHCSVSDQTSKESTSTESSSQDVESTFSSPEDSLPKSKPLTS--SRSSM 522
++ ++ S + S S E+ +S E+ + L SR +
Sbjct: 1391 KNSSPNSSPRTLGRSKGRLRLPQIGSKNKLSSSKENLDASKENGAGQICELADALSRGHV 1450
Query: 523 EMPSQPAPRTVTDEEINFVKTCLQRWRSEIEQDIQDLKTCIASTTQTIEQMYCDPLLRQV 582
SQP T D E+ L + + + S + + D ++ +
Sbjct: 1451 LGGSQPELVTPQDHEVALANGFLYEHEA-CGNGYSNGQLGNHSEEDSTDDQREDTRIKPI 1509
Query: 583 PYRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSA 642
Y L+A+ H G GHY Y N P W YND S E +E++ D SA
Sbjct: 1510 -YNLYAISCHSGILGGGHYVTYAKN-PNCKWYCYNDSSCKELHPDEIDTD--------SA 1559
Query: 643 YCLMYINDKLPYFNAEAAP-TESDQMSEVEALSVELK 678
Y L Y + Y A+ P T+ +M++ ++ + +
Sbjct: 1560 YILFYEQQGIDY--AQFLPKTDGKKMADTSSMDEDFE 1594
Score = 32.0 bits (71), Expect = 3.2
Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 10/111 (9%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLS----YSLPQNVLENCRSHTEKRNIMFMQEL 218
GL N+GNTC+ ++ IQ + + +S Y L + + H K +QE
Sbjct: 735 GLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQE- 793
Query: 219 QYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLED 269
L G+ + + K A R + QQQD E LLD L +
Sbjct: 794 -----LWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGLHE 839
>gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 344
Score = 45.4 bits (106), Expect = 3e-04
Identities = 18/47 (38%), Positives = 28/47 (59%)
Query: 584 YRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVE 630
Y L AV+ H G A++GHY YI + W +ND ++ SWE+++
Sbjct: 268 YELFAVIAHVGMADSGHYCVYIRSAVDGKWFCFNDSNICLVSWEDIQ 314
Score = 33.1 bits (74), Expect = 1.4
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 162 VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYL 221
VGL N+G TC +++IQ +F R++ ++P+ E ++R++ F ++ L
Sbjct: 21 VGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADE------QRRSVPF--QMLLL 72
Query: 222 FALMMGSNRKFVDP 235
M S +K V P
Sbjct: 73 LEKMQDSRQKAVWP 86
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 24/121 (19%)
Query: 565 STTQTIEQMYCDPLLRQVPYRLHAVLVHEGQANAGHYWAYIYNQPRQSWLKYNDISVTES 624
ST E + P+ Y L+A+ H G + GHY Y N P W YND S E
Sbjct: 1298 STDDQREDTHIKPI-----YNLYAISCHSGILSGGHYITYAKN-PNCKWYCYNDSSCEEL 1351
Query: 625 SWEEVERDSYGGLRNVSAYCLMYINDKLPYFN----------AEAAPTESDQMSEVEALS 674
+E++ D SAY L Y + Y A+ + T+ D S+ E S
Sbjct: 1352 HPDEIDTD--------SAYILFYEQQGIDYAQFLPKIDGKKMADTSSTDEDSESDYEKYS 1403
Query: 675 V 675
+
Sbjct: 1404 M 1404
Score = 30.4 bits (67), Expect = 9.4
Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 10/111 (9%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLS----YSLPQNVLENCRSHTEKRNIMFMQEL 218
GL N+GNTC+ ++ IQ + + +S Y L + + H K +QE
Sbjct: 533 GLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQE- 591
Query: 219 QYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLED 269
L G+ + + K A + QQQD E LLD L +
Sbjct: 592 -----LWSGTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHE 637
>gi|10190742 ubiquitin specific peptidase 29 [Homo sapiens]
Length = 922
Score = 44.7 bits (104), Expect = 5e-04
Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 12/141 (8%)
Query: 163 GLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQEL--QY 220
G N+GNTC+ +AV+QSLF +P F +L+ +P + ++ +++
Sbjct: 286 GFPNLGNTCYMNAVLQSLFAIPSFADDLLTQGVPWEYIPFEALIMTLTQLLALKDFCSTK 345
Query: 221 LFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWL-EDAFQLAVNVNS 279
+ ++G+ +K + SA ++ G Q D EF + LD L ED +L +N+
Sbjct: 346 IKRELLGNVKKVI--SAVAEIFSG------NMQNDAHEFLGQCLDQLKEDMEKLNATLNT 397
Query: 280 PRN-KSENPMVQLFYGTFLTE 299
+ EN Q+ G+ T+
Sbjct: 398 GKECGDENSSPQMHVGSAATK 418
Score = 42.7 bits (99), Expect = 0.002
Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 6/68 (8%)
Query: 584 YRLHAVLVHEGQA-NAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSA 642
YRL +V+ H G + N+GHY + +Y+ +Q+W YND+ V+E S +++ R S
Sbjct: 823 YRLISVVSHIGSSPNSGHYISDVYDFQKQAWFTYNDLCVSEISETKMQE-----ARLHSG 877
Query: 643 YCLMYIND 650
Y Y+++
Sbjct: 878 YIFFYMHN 885
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,871,813
Number of Sequences: 37866
Number of extensions: 1775300
Number of successful extensions: 8739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 8145
Number of HSP's gapped (non-prelim): 654
length of query: 1077
length of database: 18,247,518
effective HSP length: 113
effective length of query: 964
effective length of database: 13,968,660
effective search space: 13465788240
effective search space used: 13465788240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.