Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 16306576
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1
[Homo sapiens]
(539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H... 1096 0.0
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H... 1077 0.0
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 81 3e-15
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] 69 8e-12
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 65 2e-10
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 63 8e-10
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 62 1e-09
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 52 1e-06
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 52 2e-06
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 51 2e-06
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 51 2e-06
gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens] 48 2e-05
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 46 1e-04
gi|117938759 GNAS complex locus XLas [Homo sapiens] 45 2e-04
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi... 45 2e-04
gi|116268109 nucleotide-binding oligomerization domains 27 [Homo... 42 0.001
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c... 41 0.002
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca... 41 0.002
gi|24308207 leucine rich repeat containing 47 [Homo sapiens] 41 0.003
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 41 0.003
gi|239750101 PREDICTED: hypothetical protein [Homo sapiens] 40 0.004
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 40 0.004
gi|30520327 F-box protein 27 [Homo sapiens] 40 0.004
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens] 40 0.005
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 40 0.005
gi|110832843 TBP-associated factor 4 [Homo sapiens] 40 0.007
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 40 0.007
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 40 0.007
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 40 0.007
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 40 0.007
>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
sapiens]
Length = 539
Score = 1096 bits (2835), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ
Sbjct: 1 MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
Query: 61 RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL
Sbjct: 61 RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
Query: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK
Sbjct: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
Query: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM 240
LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM
Sbjct: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM 240
Query: 241 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 300
LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL
Sbjct: 241 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 300
Query: 301 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 360
QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE
Sbjct: 301 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 360
Query: 361 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 420
LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT
Sbjct: 361 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 420
Query: 421 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 480
SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL
Sbjct: 421 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 480
Query: 481 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 539
RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS
Sbjct: 481 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 539
>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
sapiens]
Length = 533
Score = 1077 bits (2786), Expect = 0.0
Identities = 533/539 (98%), Positives = 533/539 (98%), Gaps = 6/539 (1%)
Query: 1 MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ
Sbjct: 1 MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
Query: 61 RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL
Sbjct: 61 RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
Query: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK
Sbjct: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
Query: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM 240
LLASLEWLMPNRFSQLQRLTLIHWKSQ LVGECCPRLTFLKLSGCHGVTADALVM
Sbjct: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQ------LVGECCPRLTFLKLSGCHGVTADALVM 234
Query: 241 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 300
LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL
Sbjct: 235 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 294
Query: 301 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 360
QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE
Sbjct: 295 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 354
Query: 361 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 420
LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT
Sbjct: 355 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 414
Query: 421 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 480
SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL
Sbjct: 415 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 474
Query: 481 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 539
RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS
Sbjct: 475 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 533
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 80.9 bits (198), Expect = 3e-15
Identities = 106/418 (25%), Positives = 164/418 (39%), Gaps = 74/418 (17%)
Query: 113 DRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAK 172
DR+P +VQIF L P L R ARVCRRW A P LW T+ L+ +
Sbjct: 115 DRLPDHSMVQIFSFL-----PTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVD-- 167
Query: 173 GGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHG 232
+A K L L PN L+ +T+ + L + +CCP L L++SGC+
Sbjct: 168 ---RALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYN 224
Query: 233 VTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRM-----RKLWLTYSSQTTA 287
++ +A+ + C L LD+ S +S EA ++ +++ + Y T
Sbjct: 225 ISNEAVFDVVSLCPNLEHLDV--SGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDC 282
Query: 288 ILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGR 347
VLE G++ + C QL L L + L R
Sbjct: 283 F-------------VLE-DEGLH-----------TIAAHCTQLTHLYLRRCVRLTDEGLR 317
Query: 348 GVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP- 406
+ S++EL + S C FVS+ L + LR L + C R+T G++ +
Sbjct: 318 YLV--IYCASIKELSV--SDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAK 373
Query: 407 -CRELEQLHL-GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAF 464
C +L L+ G G +D G +L K C L+ LD+
Sbjct: 374 YCSKLRYLNARGCEGITD------HGVEYLA-KNCTKLKSLDI------------GKCPL 414
Query: 465 LSTPGGSHPALCSLNLRG------TRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLK 516
+S G AL NL+ +T + V ++C L LN++ C L+
Sbjct: 415 VSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALR 472
>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
Length = 621
Score = 69.3 bits (168), Expect = 8e-12
Identities = 84/353 (23%), Positives = 142/353 (40%), Gaps = 39/353 (11%)
Query: 105 EGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSS 164
EGP+ G+ D++P E++ I L +P L R A+ C+ + P + + L
Sbjct: 273 EGPNNGYFDKLPYELIQLILNHLT-----LPDLCRLAQTCKLLSQHCCDPLQYIHLNLQ- 326
Query: 165 PLVGRPAKGGVKAEKKLLASLEWLMPN--------------RF-----SQLQRLTLIHWK 205
P + ++ + ++WL + RF S+L RL L
Sbjct: 327 PYWAKLDDTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSH 386
Query: 206 SQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVS 265
L+++ E CP L L LS C + A +AK C L L L + VE TA++S
Sbjct: 387 FLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAK-LCSLKRLVLYRTKVEQTALLS 445
Query: 266 FLEEAGSRMR-KLWLTYSSQTTAILGALLGSCCPQLQVLEV--STGINRNSIPLQLPVEA 322
L L + ++ +++G+ C +L+ L++ I N I
Sbjct: 446 ILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGI------AE 499
Query: 323 LQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHG 382
L GCP L+ L L L G P+L++L L ++ V + + L
Sbjct: 500 LASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTAN--RSVCDTDIDELACN 557
Query: 383 SPNLRLLDLRGCARITPAGLQDL--PCRELEQLHLGLYGTSDRLTLAKEGSPF 433
L+ LD+ G ++PA L+ L C++L L + D + + + F
Sbjct: 558 CTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASF 610
Score = 38.9 bits (89), Expect = 0.012
Identities = 70/308 (22%), Positives = 122/308 (39%), Gaps = 43/308 (13%)
Query: 218 CCPRLTFLKLS---GCHGVTADALVMLAKACCQLHSLDLQ----HSMVESTAVVSFLEEA 270
CC L ++ L+ + +L L C + L+L + FL+
Sbjct: 314 CCDPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVC 373
Query: 271 GSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL 330
GS + +L L+ S ++ CP LQ L +S+ +LP +A
Sbjct: 374 GSELVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCD-------KLPPQAFNHIAKLC 426
Query: 331 QVLRLLNLMWLPKPPGRGVAPGPGFPS-LEELCLASSTCNFVSN-EVLGRLLHGS-PNLR 387
+ RL+ ++ K + F S L+ L L S C + + +V+ ++ LR
Sbjct: 427 SLKRLV--LYRTKVEQTALLSILNFCSELQHLSLGS--CVMIEDYDVIASMIGAKCKKLR 482
Query: 388 LLDLRGCARITPAGLQDLP--CRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLREL 445
LDL C IT G+ +L C LE+L LG T + S + H L L
Sbjct: 483 TLDLWRCKNITENGIAELASGCPLLEELDLGWCPTL-------QSSTGCFTRLAHQLPNL 535
Query: 446 D----LSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTR-VTPSTVSSVISSCPGL 500
+ + + D+++ + L L++ GTR V+P+++ ++ SC L
Sbjct: 536 QKLFLTANRSVCDTDIDELAC--------NCTRLQQLDILGTRMVSPASLRKLLESCKDL 587
Query: 501 LYLNLESC 508
L++ C
Sbjct: 588 SLLDVSFC 595
Score = 30.0 bits (66), Expect = 5.6
Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 7/107 (6%)
Query: 407 CRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLS 466
C L+ +HL L +L + S Q C ++ L+LS G + FL
Sbjct: 315 CDPLQYIHLNLQPYWAKLD---DTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLK 371
Query: 467 TPGGSHPALCSLNLRGTRVTPSTVSSVISS-CPGLLYLNLESCRCLP 512
G L L L + T VIS CP L LNL SC LP
Sbjct: 372 VCGSE---LVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLP 415
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 65.1 bits (157), Expect = 2e-10
Identities = 99/432 (22%), Positives = 163/432 (37%), Gaps = 43/432 (9%)
Query: 114 RIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
++P E+L++IF L L R A+V R W A + W + L R +G
Sbjct: 27 KLPKELLLRIFSFLDVVT-----LCRCAQVSRAWNVLALDGSNWQRIDLFD--FQRDIEG 79
Query: 174 GVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGV 233
V +E + L++L+L L+ + C + L L+GC
Sbjct: 80 RV---------VENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKT 130
Query: 234 TADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALL 293
T L+K C +L LDL + + L E + +L +++ Q T L
Sbjct: 131 TDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQAL 190
Query: 294 GSCCPQLQVLEVSTGINRNSIPLQLPVEALQ---KGCPQLQVLRLLNLMWLPKPPGRGVA 350
C L+ L + QL EAL+ CP+L L L + + +
Sbjct: 191 VRGCGGLKALFLKG-------CTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITIC 243
Query: 351 PGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CR 408
G L+ LC +S C+ +++ +L L P LR+L++ C+++T G L C
Sbjct: 244 --RGCHKLQSLC--ASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCH 299
Query: 409 ELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTP 468
ELE++ L + + + C L+ L LS D L
Sbjct: 300 ELEKMDL------EECVQITDSTLIQLSIHCPRLQVLSLSHCELITDD----GIRHLGNG 349
Query: 469 GGSHPALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESCRCLPR-GLKRAYRGLEEVQW 527
+H L + L + + SC L + L C+ + R G+KR L ++
Sbjct: 350 ACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKV 409
Query: 528 CLEQLLTSPSPS 539
+P PS
Sbjct: 410 HAYFAPVTPPPS 421
>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
Length = 418
Score = 62.8 bits (151), Expect = 8e-10
Identities = 101/404 (25%), Positives = 165/404 (40%), Gaps = 70/404 (17%)
Query: 118 EILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKA 177
E+L IFG L D GRAA+VC W++AA ++W GV+A
Sbjct: 11 ELLAMIFGYLDVRDK-----GRAAQVCTAWRDAAYHKSVWR---------------GVEA 50
Query: 178 EKKLLASLEWLMPNRFSQ-LQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTAD 236
+ L + L P+ ++ ++R+ ++ + + V++ + + L LSGC+ +T +
Sbjct: 51 KLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMA----NIESLNLSGCYNLTDN 106
Query: 237 ALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC 296
L +F++E GS +R L L+ Q T +
Sbjct: 107 GLGH------------------------AFVQEIGS-LRALNLSLCKQITDSSLGRIAQY 141
Query: 297 CPQLQVLEVSTGINRNSIPLQLPVEALQK-GCPQLQVLRLLNLMWLPKPPGRGVAPGPGF 355
L+VLE+ N + L L LQ+ L+ R L+ + + G + G
Sbjct: 142 LKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGC 201
Query: 356 PSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHL 415
LE+L L C +++ L + G LRLL+L C I+ AGL LHL
Sbjct: 202 LGLEQLTL--QDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGL----------LHL 249
Query: 416 GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSG--QGFSEKDLEQALAAFLSTPGGSHP 473
G+ L L + T + L LSG F +K +Q+LA G
Sbjct: 250 SHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDG--- 306
Query: 474 ALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESC-RCLPRGLK 516
L SL+L ++ ++ ++ GL LN+ C R +GL+
Sbjct: 307 -LKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLE 349
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 62.0 bits (149), Expect = 1e-09
Identities = 101/417 (24%), Positives = 162/417 (38%), Gaps = 39/417 (9%)
Query: 114 RIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
++P E+L++IF L + L R A++ + W A + W + L + + +G
Sbjct: 14 KLPKELLLRIFSFL-----DIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQID--VEG 66
Query: 174 GVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGV 233
V +E + L++L+L LK + C + L L+GC +
Sbjct: 67 RV---------VENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKI 117
Query: 234 TADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALL 293
T L++ C +L LDL + + + + + E + L L++ Q T L
Sbjct: 118 TDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEAL 177
Query: 294 GSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAP-G 352
C L+ L + G QL EAL+ L LNL + GV
Sbjct: 178 VRGCRGLKAL-LLRGCT------QLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQIC 230
Query: 353 PGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CREL 410
G L+ LCL S C+ +++ L L P L++L+ C+ +T AG L C EL
Sbjct: 231 RGCHRLQALCL--SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHEL 288
Query: 411 EQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGG 470
E++ L + L + + C L+ L LS D LS
Sbjct: 289 EKMDL------EECILITDSTLIQLSIHCPKLQALSLSHCELITDD----GILHLSNSTC 338
Query: 471 SHPALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESCRCLPR-GLKRAYRGLEEVQ 526
H L L L + + +C GL L L C+ + R G+KR L V+
Sbjct: 339 GHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
[Homo sapiens]
Length = 690
Score = 52.0 bits (123), Expect = 1e-06
Identities = 72/317 (22%), Positives = 115/317 (36%), Gaps = 65/317 (20%)
Query: 188 LMPNRFSQLQRLTLIHWKSQVHPVLKLV--GECCPRLTFLKLSGCHGVTADALVMLAKAC 245
L+P F LQ L+L + + L+ + G C +L +L LSGC ++ +A +C
Sbjct: 290 LLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSC 349
Query: 246 CQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC--------- 296
+ L + + V L E SR+ L T + + L +C
Sbjct: 350 TGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEG 409
Query: 297 ---------------CPQLQVLEVST--GINRNSIPLQLPVEALQKGCPQLQVLRLLNLM 339
P L + ++ GI +S+ P++ QL VL L N +
Sbjct: 410 NKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLK-------QLTVLNLANCV 462
Query: 340 WLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 399
+ + GP + EL L S C +S+ + +L PNL L LR C +T
Sbjct: 463 RIGDMGLKQFLDGPASMRIRELNL--SNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTA 520
Query: 400 AGLQ-----------DLPCRELEQLHLGLYG----------------TSDRLTLAKEGSP 432
G+ DL ++ L + T D + +
Sbjct: 521 QGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQITDSAME 580
Query: 433 FLTQKWCHTLRELDLSG 449
L+ K CH L LD+SG
Sbjct: 581 MLSAK-CHYLHILDISG 596
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
[Homo sapiens]
Length = 735
Score = 51.6 bits (122), Expect = 2e-06
Identities = 58/243 (23%), Positives = 94/243 (38%), Gaps = 37/243 (15%)
Query: 188 LMPNRFSQLQRLTLIHWKSQVHPVLKLV--GECCPRLTFLKLSGCHGVTADALVMLAKAC 245
L+P F LQ L+L + + L+ + G C +L +L LSGC ++ +A +C
Sbjct: 290 LLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSC 349
Query: 246 CQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC--------- 296
+ L + + V L E SR+ L T + + L +C
Sbjct: 350 TGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEG 409
Query: 297 ---------------CPQLQVLEVST--GINRNSIPLQLPVEALQKGCPQLQVLRLLNLM 339
P L + ++ GI +S+ P++ QL VL L N +
Sbjct: 410 NKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLK-------QLTVLNLANCV 462
Query: 340 WLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 399
+ + GP + EL L S C +S+ + +L PNL L LR C +T
Sbjct: 463 RIGDMGLKQFLDGPASMRIRELNL--SNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTA 520
Query: 400 AGL 402
G+
Sbjct: 521 QGI 523
Score = 40.0 bits (92), Expect = 0.005
Identities = 22/86 (25%), Positives = 43/86 (50%)
Query: 196 LQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQH 255
L+ L + + ++K + C LT L ++GC +T A+ ML+ C LH LD+
Sbjct: 582 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 641
Query: 256 SMVESTAVVSFLEEAGSRMRKLWLTY 281
++ + ++ L+ ++R L + Y
Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQY 667
Score = 31.6 bits (70), Expect = 1.9
Identities = 51/217 (23%), Positives = 85/217 (39%), Gaps = 26/217 (11%)
Query: 211 VLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEA 270
V+KL E CP L +L L C +TA + + L S+DL + + + +
Sbjct: 497 VMKL-SERCPNLNYLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTDISNEGL-----NV 549
Query: 271 GSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL 330
SR +KL S+ I + + C +LE ++ S + ++AL C L
Sbjct: 550 LSRHKKLKELSVSECYRITDDGIQAFCKSSLILE-HLDVSYCSQLSDMIIKALAIYCINL 608
Query: 331 QVLRLLNLMWLPKPPGRGVAPGPGFPSLEELC-----LASSTCNFVSNEVLGRLLHGSPN 385
L + PK L C L S C +++++L L G
Sbjct: 609 TSLSIAGC---PK------ITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQ 659
Query: 386 LRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGTSD 422
LR+L ++ C I+ Q + + +Q Y T+D
Sbjct: 660 LRILKMQYCTNISKKAAQRMSSKVQQQ----EYNTND 692
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/185 (25%), Positives = 77/185 (41%), Gaps = 36/185 (19%)
Query: 99 PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158
P E P W D +P E+L+ IF L +P L + + VC+RW AS +LW
Sbjct: 85 PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138
Query: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRFS--QLQRLTLIHWKSQVHPV 211
T+ L+ + GR GV A + + ++ + FS ++Q + L + +V +
Sbjct: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198
Query: 212 LKLVGECC-----------------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248
++ +C L L LSGC G + AL L +C +L
Sbjct: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258
Query: 249 HSLDL 253
L+L
Sbjct: 259 DELNL 263
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/185 (25%), Positives = 77/185 (41%), Gaps = 36/185 (19%)
Query: 99 PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158
P E P W D +P E+L+ IF L +P L + + VC+RW AS +LW
Sbjct: 85 PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138
Query: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRFS--QLQRLTLIHWKSQVHPV 211
T+ L+ + GR GV A + + ++ + FS ++Q + L + +V +
Sbjct: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198
Query: 212 LKLVGECC-----------------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248
++ +C L L LSGC G + AL L +C +L
Sbjct: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258
Query: 249 HSLDL 253
L+L
Sbjct: 259 DELNL 263
>gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens]
Length = 374
Score = 48.1 bits (113), Expect = 2e-05
Identities = 70/245 (28%), Positives = 99/245 (40%), Gaps = 42/245 (17%)
Query: 112 GDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSP------ 165
G+ +P E+L IF L D AARVCR W AA+ A+WH +S
Sbjct: 5 GEGLPEEVLALIFRHLSLRDR-----AAAARVCRAWAAAATCSAVWHDTKISCECELEGM 59
Query: 166 ----------------LVGRPAKGGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQV- 208
L P++ K ++ L ++ R L+ L L +
Sbjct: 60 LPPYLSACLDHIHNLRLEFEPSR---KPSRRAAIELLMVLAGRAPGLRGLRLECRGEKPL 116
Query: 209 ----HPVLKLVGECC---PRLTFLKLSGCHGVTADALVM-LAKACCQLHSLDLQHS-MVE 259
VL+ V C +L L L DALV+ A++C +LHSL L +S +V
Sbjct: 117 FDAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELHSLFLDNSTLVG 176
Query: 260 STAVVSFLE--EAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQ 317
S S LE EA R+R L L +S + AIL AL +L + ++
Sbjct: 177 SVGPGSVLELLEACPRLRALGLHLASLSHAILEALAAPDRAPFALLALRCACPEDARASP 236
Query: 318 LPVEA 322
LP EA
Sbjct: 237 LPNEA 241
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 45.8 bits (107), Expect = 1e-04
Identities = 97/398 (24%), Positives = 140/398 (35%), Gaps = 75/398 (18%)
Query: 63 ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLE---- 118
A++ P QPP P+ A S AA A P TP GP + P E
Sbjct: 41 ATKNRPCQPPPPPTLPPPSLAAPLSRAALAGGPC-----TPAGGPASALAPGHPAERPPL 95
Query: 119 -----ILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH--TVTLSSPLVGRPA 171
IL +F A + + A+VC+ W+ QP W T L + +
Sbjct: 96 ATDEKILNGLFWYFSACEKCV-----LAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVL 150
Query: 172 KGGVKAEKKL------------------LASLEWLMPNRFSQ-------LQRLTLIH--- 203
GG K L L E++ S+ L+R T+
Sbjct: 151 PGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGL 210
Query: 204 --WKSQVHPVLKLVGECC-------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248
Q+ V++L C R+T L +S C V DA+ +++ L
Sbjct: 211 EVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNL 270
Query: 249 HSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTG 308
L LQ V TA+ F G L L + T + P L L +S
Sbjct: 271 AELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGC 330
Query: 309 INRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVA-PGPGFPSLEELCLASST 367
++L E L+K LR L+L W P+ + LEEL L
Sbjct: 331 SKVTDDGVELVAENLRK-------LRSLDLSWCPRITDMALEYVACDLHRLEELVL--DR 381
Query: 368 CNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDL 405
C +++ L L S +LR L LR C ++ GL+ L
Sbjct: 382 CVRITDTGLSYLSTMS-SLRSLYLRWCCQVQDFGLKHL 418
Score = 40.0 bits (92), Expect = 0.005
Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 18/149 (12%)
Query: 204 WKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLD----------- 252
W+ H V+ +V P LT L LSGC VT D + ++A+ +L SLD
Sbjct: 305 WEITNHGVVNVV-HSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363
Query: 253 LQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRN 312
L++ + + + + R+ L+Y S +++ L CC Q+Q + +
Sbjct: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCC-QVQDFGLKHLLALG 422
Query: 313 SIPLQLPVEALQKGCPQLQVLRLLNLMWL 341
S+ L P GCP L L L+ L
Sbjct: 423 SLRLLSPA-----GCPLLTTTGLSGLVQL 446
Score = 35.0 bits (79), Expect = 0.17
Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)
Query: 356 PSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPC--RELEQL 413
P+L L L S C+ V+++ + + LR LDL C RIT L+ + C LE+L
Sbjct: 320 PNLTALSL--SGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEEL 377
Query: 414 HLGL------YGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLST 467
L G S T++ S +L +WC + Q F K L + L +
Sbjct: 378 VLDRCVRITDTGLSYLSTMSSLRSLYL--RWCCQV-------QDFGLKHLLALGSLRLLS 428
Query: 468 PGGSHPALCSLNLRGTRVTPSTVSSVISSCPG-----LLYLNLESCRCL 511
P G P L + L G +++CPG Y + RCL
Sbjct: 429 PAGC-PLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCL 476
>gi|117938759 GNAS complex locus XLas [Homo sapiens]
Length = 1037
Score = 44.7 bits (104), Expect = 2e-04
Identities = 48/173 (27%), Positives = 64/173 (36%), Gaps = 25/173 (14%)
Query: 16 APRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQRRASRRTPRQPPRGP 75
+P P A + +D+ A RG LLQ + P P A P PP P
Sbjct: 155 SPPPEEAMPFEFDQPAQRGCSQLLLQVPDL-------APGGPGAAG-----VPGAPPEEP 202
Query: 76 SAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMP 135
A KAG R +P P T P E G+GD P L ++ + DG
Sbjct: 203 QALRPAKAGSRG----GYSPPPEET-MPFELDGEGFGDDSPPPGLSRV---IAQVDGSSQ 254
Query: 136 FLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKKLLASLEWL 188
F AA R AA+ P LW +G P++ V+ S W+
Sbjct: 255 FAAVAASSAVRLTPAANAPPLW-----VPGAIGSPSQEAVRPPSNFTGSSPWM 302
Score = 30.0 bits (66), Expect = 5.6
Identities = 25/65 (38%), Positives = 26/65 (40%), Gaps = 4/65 (6%)
Query: 50 SEPGPARPR-AQRRASRRTPRQPPRG--PSAAAKPKAGLRSEAAAAPAPAPA-PTPTPEE 105
S PA P A+ P P G P A A P AG EA AAPA A
Sbjct: 431 SGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPA 490
Query: 106 GPDAG 110
PDAG
Sbjct: 491 APDAG 495
Score = 30.0 bits (66), Expect = 5.6
Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 20/78 (25%)
Query: 54 PARPRA-QRRASRRTPRQP----PRGPSAAAKPKAGLRSEAAAAPA-----------PAP 97
PA P A + RA+ P P P P+A+A A +R A+AAPA P+P
Sbjct: 474 PAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSP 533
Query: 98 ----APTPTPEEGPDAGW 111
A PTP + W
Sbjct: 534 EIQAADPPTPRPTRASAW 551
>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
sapiens]
Length = 300
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 5/125 (4%)
Query: 212 LKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQH-SMVESTAVVSFLEEA 270
L + E CPRL L L+ C V AL LA C L LDL ++ A+V +
Sbjct: 132 LGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRR 191
Query: 271 GSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL 330
G+ +R L L ++ L CP+L L+++ + S V L + CP L
Sbjct: 192 GAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD----GVRTLAEYCPVL 247
Query: 331 QVLRL 335
+ LR+
Sbjct: 248 RSLRV 252
Score = 42.7 bits (99), Expect = 8e-04
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 12/135 (8%)
Query: 322 ALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLL- 380
AL +GCP+LQ L L + W+ RG+A P+LEEL L + C + +E + L
Sbjct: 134 ALAEGCPRLQRLSLAHCDWVDGLALRGLA--DRCPALEELDL--TACRQLKDEAIVYLAQ 189
Query: 381 HGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT----SDRLTLAKEGSPFLTQ 436
LR L L A + A +Q+L E HL L G SD + E P L
Sbjct: 190 RRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249
Query: 437 ---KWCHTLRELDLS 448
+ CH + E LS
Sbjct: 250 LRVRHCHHVAESSLS 264
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 358 LEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CRELEQLHL 415
L+EL LA ++S+E L +L +P LR + L GC +++ L L C L++L L
Sbjct: 89 LQELALAPCH-EWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSL 147
Query: 416 GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPAL 475
D L L C L ELDL+ + + L+ +L+ G+ L
Sbjct: 148 AHCDWVDGLALRGLADR------CPALEELDLT----ACRQLKDEAIVYLAQRRGA--GL 195
Query: 476 CSLNLR-GTRVTPSTVSSVISSCPGLLYLNLESC 508
SL+L V + V + +CP L +L+L C
Sbjct: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGC 229
Score = 33.9 bits (76), Expect = 0.39
Identities = 24/88 (27%), Positives = 44/88 (50%)
Query: 184 SLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAK 243
++ +L R + L+ L+L + ++ + CP L L L+GC V +D + LA+
Sbjct: 183 AIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAE 242
Query: 244 ACCQLHSLDLQHSMVESTAVVSFLEEAG 271
C L SL ++H + + +S L + G
Sbjct: 243 YCPVLRSLRVRHCHHVAESSLSRLRKRG 270
>gi|116268109 nucleotide-binding oligomerization domains 27 [Homo
sapiens]
Length = 1866
Score = 42.4 bits (98), Expect = 0.001
Identities = 82/300 (27%), Positives = 116/300 (38%), Gaps = 59/300 (19%)
Query: 223 TFLKLSGCHGVTADALVMLAKA---CCQLHSLDLQHSMVESTAVVSFLE--EAGSRMRKL 277
TF S C V+ + L LA C L LDL ++ + + + E +++L
Sbjct: 1498 TFRLTSSC--VSTEGLAHLASGLGHCHHLEELDLSNNQFDEEGTKALMRALEGKWMLKRL 1555
Query: 278 WLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL-QVLRLL 336
L++ ++ L ALL Q+ L+ S +NRNSI GC L + LR
Sbjct: 1556 DLSHLLLNSSTL-ALLTHRLSQMTCLQ-SLRLNRNSIG--------DVGCCHLSEALRAA 1605
Query: 337 NLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCAR 396
SLEEL L+ + + L +L G P LR +DL G +
Sbjct: 1606 T-------------------SLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSI 1646
Query: 397 ITPAGLQ----DLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGF 452
+ G+Q + CR LE+L LG D L L Q+ LR L L F
Sbjct: 1647 SSAGGVQLAESLVLCRRLEELMLGCNALGDPTALG------LAQELPQHLRVLHLP---F 1697
Query: 453 SEKDLEQALAAFLSTPGGSHPALCSL---NLRGTRVTPSTVSSVISSCPGLLYLNLESCR 509
S AL+ + G H SL NL G V P L ++L SC+
Sbjct: 1698 SHLGPGGALSLAQALDGSPHLEEISLAENNLAG------GVLRFCMELPLLRQIDLVSCK 1751
>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 1 [Homo sapiens]
Length = 964
Score = 41.2 bits (95), Expect = 0.002
Identities = 73/280 (26%), Positives = 109/280 (38%), Gaps = 53/280 (18%)
Query: 14 RAAPRPRSAED-WWWDRLAPRGSGYHLLQSDSMLLVLSEPGPA----RPRAQRRASRRTP 68
RA+PRP + ED W +P G G DS LL LS PGP RP + R +
Sbjct: 282 RASPRPWTPEDPWSLYGPSPGGRG----PEDSWLL-LSAPGPTPASPRPASPCGKRRYSS 336
Query: 69 RQPPRGPSAAAKPKAGLRSEAAAAPAPAPAP------TPTPEEGPDAGWGDRIPLEILVQ 122
P S A + L E + P P P P +P P + A + IP +
Sbjct: 337 SGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRT 396
Query: 123 IFGLLVA---------ADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
VA +G +P LG V + + A + + SPL A+
Sbjct: 397 SSEQAVALPRSEEPASCNGKLP-LGAEESVAPP-GGSRKEVAGMDYLAVPSPLAWSKARI 454
Query: 174 GVKA---EKKLLASLEWLMPNRFSQLQ-RLTL-------IHWKSQ-----------VHPV 211
G + L L+W +P+++ QL+ R+ + H++++ HPV
Sbjct: 455 GGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPV 514
Query: 212 LKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSL 251
+KL+G LT G TAD + A Q+H +
Sbjct: 515 VKLLGYSEKPLTLQMFIG----TADERNLRPHAFYQVHRI 550
>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 2 [Homo sapiens]
Length = 902
Score = 41.2 bits (95), Expect = 0.002
Identities = 73/280 (26%), Positives = 109/280 (38%), Gaps = 53/280 (18%)
Query: 14 RAAPRPRSAED-WWWDRLAPRGSGYHLLQSDSMLLVLSEPGPA----RPRAQRRASRRTP 68
RA+PRP + ED W +P G G DS LL LS PGP RP + R +
Sbjct: 219 RASPRPWTPEDPWSLYGPSPGGRG----PEDSWLL-LSAPGPTPASPRPASPCGKRRYSS 273
Query: 69 RQPPRGPSAAAKPKAGLRSEAAAAPAPAPAP------TPTPEEGPDAGWGDRIPLEILVQ 122
P S A + L E + P P P P +P P + A + IP +
Sbjct: 274 SGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRT 333
Query: 123 IFGLLVA---------ADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
VA +G +P LG V + + A + + SPL A+
Sbjct: 334 SSEQAVALPRSEEPASCNGKLP-LGAEESVAPP-GGSRKEVAGMDYLAVPSPLAWSKARI 391
Query: 174 GVKA---EKKLLASLEWLMPNRFSQLQ-RLTL-------IHWKSQ-----------VHPV 211
G + L L+W +P+++ QL+ R+ + H++++ HPV
Sbjct: 392 GGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPV 451
Query: 212 LKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSL 251
+KL+G LT G TAD + A Q+H +
Sbjct: 452 VKLLGYSEKPLTLQMFIG----TADERNLRPHAFYQVHRI 487
>gi|24308207 leucine rich repeat containing 47 [Homo sapiens]
Length = 583
Score = 40.8 bits (94), Expect = 0.003
Identities = 48/175 (27%), Positives = 67/175 (38%), Gaps = 29/175 (16%)
Query: 328 PQLQVLRLLNLMWLPKPPGRGVAPG--PGFPSLEELCLASSTCNFVSNEVLGRLLHGSPN 385
P L+VL L PPG+G+ P PG P L+ L L+ + E+ L +P
Sbjct: 99 PALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRL----RELPADLARCAPR 154
Query: 386 LRLLDLRG-CARITPAGLQDLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCH--TL 442
L+ L+L G C PA E G L A L+ H +L
Sbjct: 155 LQSLNLTGNCLDSFPA----------ELFRPGALPLLSELAAADNCLRELSPDIAHLASL 204
Query: 443 RELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTRVTPSTVSSVISSC 497
+ LDLS SE E A P L +N RG ++ + ++S C
Sbjct: 205 KTLDLSNNQLSEIPAELA----------DCPKLKEINFRGNKLRDKRLEKMVSGC 249
>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
sapiens]
Length = 694
Score = 40.8 bits (94), Expect = 0.003
Identities = 94/360 (26%), Positives = 135/360 (37%), Gaps = 81/360 (22%)
Query: 48 VLSEP-GPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEG 106
+LS P GPA P + R R PPR P E P A + P P
Sbjct: 381 LLSWPLGPAPPPRPPQLERHVVRPPPRSP------------EPDTLPLAAGSDHPLPR-- 426
Query: 107 PDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLS-SP 165
A W +++F L GP L RVCR W LW + LS
Sbjct: 427 --AAW---------LRVFQHL----GPRE-LCICMRVCRTWSRWCYDKRLWPRMDLSRRK 470
Query: 166 LVGRPAKGGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFL 225
+ P GV + L W S+ Q + L++ +L G L L
Sbjct: 471 SLTPPMLSGVVRRQPRALDLSW---TGVSKKQLMWLLN---------RLQG-----LQEL 513
Query: 226 KLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEA-GSRMRKLWL----T 280
LSGC ++ AL +L LDL+ ++E+ S++R+L L T
Sbjct: 514 VLSGCSWLSVSALGSAPLPALRL--LDLR-----------WIEDVKDSQLRELLLPPPDT 560
Query: 281 YSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMW 340
QT + G L G +L LE++ + L + PQL L L +
Sbjct: 561 KPGQTES-RGRLQGVAELRLAGLELT----------DASLRLLLRHAPQLSALDLSHCAH 609
Query: 341 LPKPPGRGVAPGPGFPSLEELC-LASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 399
+ P + P P E L L + C+ +++ L L P LR LDLR C +++P
Sbjct: 610 VGDPSVH-LLTAPTSPLRETLVHLNLAGCHRLTDHCL-PLFRRCPRLRRLDLRSCRQLSP 667
>gi|239750101 PREDICTED: hypothetical protein [Homo sapiens]
Length = 365
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/60 (45%), Positives = 29/60 (48%), Gaps = 8/60 (13%)
Query: 51 EPGPARPRAQRR---ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGP 107
EP PA PRA R A+RR P PP P A A+P G RS PA P PT P
Sbjct: 306 EPRPAEPRAPPRPPPAARRPP--PPPAPGAPARPLRGRRSH---GPAARPRAVPTTSLAP 360
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 45 MLLVLSEPGPAR--PRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPT 102
M+L EP AR AQ T PP GP + P+A + PA A
Sbjct: 1 MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE 60
Query: 103 PEEGPDAGWG 112
P E P+ GWG
Sbjct: 61 PPEPPEGGWG 70
>gi|30520327 F-box protein 27 [Homo sapiens]
Length = 283
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 7/64 (10%)
Query: 94 APAPAPTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQ 153
A PAP P PEE D ++P E+L+ + + P LGR +VCR W+
Sbjct: 11 ARVPAPEPEPEEALDLS---QLPPELLLVVLSHVP----PRTLLGRCRQVCRGWRALVDG 63
Query: 154 PALW 157
ALW
Sbjct: 64 QALW 67
>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
Length = 175
Score = 40.0 bits (92), Expect = 0.005
Identities = 22/59 (37%), Positives = 25/59 (42%)
Query: 52 PGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAG 110
PG A A R + R P PP P P AGL A + P+PAP P P G
Sbjct: 114 PGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 66 RTPRQPPRGPSAAAKPKAGLRSEA-AAAPAPAPAPTPTPEEGPDA 109
RTP +P GP+A A A + A A+APAPAP PTP P +
Sbjct: 415 RTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSS 459
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 39.7 bits (91), Expect = 0.007
Identities = 37/115 (32%), Positives = 40/115 (34%), Gaps = 23/115 (20%)
Query: 15 AAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQRR------------ 62
AAP P A R P G G S L GPA P A+ R
Sbjct: 85 AAPEPPPA-----GRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP 139
Query: 63 -----ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWG 112
A P P GP+ A P A L + A P P P P P P G AG G
Sbjct: 140 VPAAAAVAAGPEPAPAGPAKPAGP-AALAARAGPGPGPGPGPGPGPGPGKPAGPG 193
Score = 30.4 bits (67), Expect = 4.3
Identities = 36/124 (29%), Positives = 44/124 (35%), Gaps = 7/124 (5%)
Query: 48 VLSEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAP---APAPTPTP- 103
+L P PA P + P P+A + P A + AAAP P APA P
Sbjct: 225 LLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP 284
Query: 104 --EEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVT 161
GP +P Q G AA P P G A V + A+ A V
Sbjct: 285 GHPAGPPTA-APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343
Query: 162 LSSP 165
SP
Sbjct: 344 AESP 347
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 39.7 bits (91), Expect = 0.007
Identities = 20/41 (48%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 68 PRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPD 108
P PP PS A P A + E A PAP PA PTPE P+
Sbjct: 508 PAAPPAAPSTPAPPPA-VPKELPAPPAPPPASAPTPETEPE 547
Score = 32.0 bits (71), Expect = 1.5
Identities = 19/63 (30%), Positives = 21/63 (33%), Gaps = 1/63 (1%)
Query: 50 SEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDA 109
S G RP +P P P A + PAP P P P P GP
Sbjct: 363 SASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKP-PLPPPHRGPAG 421
Query: 110 GWG 112
WG
Sbjct: 422 NWG 424
Score = 29.6 bits (65), Expect = 7.3
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 15/85 (17%)
Query: 49 LSEPGPAR----PRAQRRASRRTP---RQPPR-------GPSAAAKPKAGLRSEAAAAPA 94
L EPGP P + A +TP ++PP+ GP A KP G+ S P
Sbjct: 856 LEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPP 915
Query: 95 PAPAPTPTPEEGPDAGWGDR-IPLE 118
P GP G R IP E
Sbjct: 916 PRRESRTETRWGPRPGSSRRGIPPE 940
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 39.7 bits (91), Expect = 0.007
Identities = 23/68 (33%), Positives = 28/68 (41%)
Query: 40 LQSDSMLLVLSEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAP 99
L + S L PGP +P A P P GP AA G S + P+P P
Sbjct: 1027 LPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVP 1086
Query: 100 TPTPEEGP 107
+P P GP
Sbjct: 1087 SPAPSPGP 1094
>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
Length = 843
Score = 39.7 bits (91), Expect = 0.007
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 47 LVLSEPGPARPRAQRRASRRT---------PRQPPRGPSAAAKPKAGLRSEAAAAPAPAP 97
+V E GP + + R+T + G S + G R++ A +
Sbjct: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
Query: 98 APTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW 157
+ P E +++P E++++IF L+ D L RAA VC+R+ E A+ P LW
Sbjct: 61 DLSAAPAE---QYLQEKLPDEVVLKIFSYLLEQD-----LCRAACVCKRFSELANDPILW 112
>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
Length = 686
Score = 39.7 bits (91), Expect = 0.007
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 47 LVLSEPGPARPRAQRRASRRT---------PRQPPRGPSAAAKPKAGLRSEAAAAPAPAP 97
+V E GP + + R+T + G S + G R++ A +
Sbjct: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
Query: 98 APTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW 157
+ P E +++P E++++IF L+ D L RAA VC+R+ E A+ P LW
Sbjct: 61 DLSAAPAE---QYLQEKLPDEVVLKIFSYLLEQD-----LCRAACVCKRFSELANDPILW 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,743,815
Number of Sequences: 37866
Number of extensions: 1414369
Number of successful extensions: 15218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 534
Number of HSP's that attempted gapping in prelim test: 11601
Number of HSP's gapped (non-prelim): 3301
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.