BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|15812196 F-box only protein 24 isoform 1 [Homo sapiens] (580 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|15812196 F-box only protein 24 isoform 1 [Homo sapiens] 1197 0.0 gi|11024696 F-box only protein 24 isoform 2 [Homo sapiens] 607 e-173 gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens] 50 4e-06 gi|4557445 regulator of chromosome condensation and BTB domain c... 50 6e-06 gi|209969703 regulator of chromosome condensation 2 [Homo sapiens] 47 5e-05 gi|29789090 regulator of chromosome condensation 2 [Homo sapiens] 47 5e-05 gi|57242759 regulator of chromosome condensation (RCC1) and BTB ... 45 2e-04 gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 44 5e-04 gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 44 5e-04 gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 44 5e-04 gi|126116565 MYC binding protein 2 [Homo sapiens] 42 0.001 gi|42558258 F-box protein 33 [Homo sapiens] 42 0.001 gi|83035136 F-box protein 31 [Homo sapiens] 42 0.002 gi|37620181 hect domain and RLD 4 isoform b [Homo sapiens] 40 0.006 gi|63025188 hect domain and RLD 4 isoform a [Homo sapiens] 40 0.006 gi|126032348 hect domain and RLD 2 [Homo sapiens] 39 0.010 gi|114796646 regulator of chromosome condensation 1 isoform b [H... 39 0.010 gi|114796644 regulator of chromosome condensation 1 isoform a [H... 39 0.010 gi|4502801 regulator of chromosome condensation 1 isoform c [Hom... 39 0.010 gi|114796642 regulator of chromosome condensation 1 [Homo sapiens] 39 0.010 gi|114796640 regulator of chromosome condensation 1 [Homo sapiens] 39 0.010 gi|114796648 regulator of chromosome condensation 1 [Homo sapiens] 39 0.010 gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo... 39 0.017 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 39 0.017 gi|13540582 Williams-Beuren syndrome chromosome region 16 [Homo ... 39 0.017 gi|7657152 hect domain and RLD 3 [Homo sapiens] 38 0.029 gi|239750800 PREDICTED: hypothetical protein XP_002347563 [Homo ... 37 0.038 gi|30039692 NIMA-related kinase 8 [Homo sapiens] 36 0.085 gi|63054860 RCC1 domain containing 1 [Homo sapiens] 36 0.11 gi|63054858 RCC1 domain containing 1 [Homo sapiens] 36 0.11 >gi|15812196 F-box only protein 24 isoform 1 [Homo sapiens] Length = 580 Score = 1197 bits (3096), Expect = 0.0 Identities = 580/580 (100%), Positives = 580/580 (100%) Query: 1 MGEKAVPLLRRRRVKRSCPSCGSELGVEEKRGKGNPISIQLFPPELVEHIISFLPVRDLV 60 MGEKAVPLLRRRRVKRSCPSCGSELGVEEKRGKGNPISIQLFPPELVEHIISFLPVRDLV Sbjct: 1 MGEKAVPLLRRRRVKRSCPSCGSELGVEEKRGKGNPISIQLFPPELVEHIISFLPVRDLV 60 Query: 61 ALGQTCRYFHEVCDGEGVWRRICRRLSPRLQDQGSGVRPWKRAAILNYTKGLYFQAFGGR 120 ALGQTCRYFHEVCDGEGVWRRICRRLSPRLQDQGSGVRPWKRAAILNYTKGLYFQAFGGR Sbjct: 61 ALGQTCRYFHEVCDGEGVWRRICRRLSPRLQDQGSGVRPWKRAAILNYTKGLYFQAFGGR 120 Query: 121 RRCLSKSVAPLLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSTLGQMQWKRACRYVVL 180 RRCLSKSVAPLLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSTLGQMQWKRACRYVVL Sbjct: 121 RRCLSKSVAPLLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSTLGQMQWKRACRYVVL 180 Query: 181 CRGAKDFASDPRCDTVYRKYLYVLATREPQEVVGTTSSRACDCVEVYLQSSGQRVFKMTF 240 CRGAKDFASDPRCDTVYRKYLYVLATREPQEVVGTTSSRACDCVEVYLQSSGQRVFKMTF Sbjct: 181 CRGAKDFASDPRCDTVYRKYLYVLATREPQEVVGTTSSRACDCVEVYLQSSGQRVFKMTF 240 Query: 241 HHSMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPH 300 HHSMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPH Sbjct: 241 HHSMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPH 300 Query: 301 LRVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMPLALSLPAKIL 360 LRVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMPLALSLPAKIL Sbjct: 301 LRVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMPLALSLPAKIL 360 Query: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCGLNHSL 420 FCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCGLNHSL Sbjct: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCGLNHSL 420 Query: 421 VLSQSSEFSKELLGCGCGAGGRLPGWPKGSASFVKLQVKVPLCACALCATRECLYILSSH 480 VLSQSSEFSKELLGCGCGAGGRLPGWPKGSASFVKLQVKVPLCACALCATRECLYILSSH Sbjct: 421 VLSQSSEFSKELLGCGCGAGGRLPGWPKGSASFVKLQVKVPLCACALCATRECLYILSSH 480 Query: 481 DIEQHAPYRHLPASRVVGTPEPSLGARAPQDPGGMAQACEEYLSQIHSCQTLQDRTEKMK 540 DIEQHAPYRHLPASRVVGTPEPSLGARAPQDPGGMAQACEEYLSQIHSCQTLQDRTEKMK Sbjct: 481 DIEQHAPYRHLPASRVVGTPEPSLGARAPQDPGGMAQACEEYLSQIHSCQTLQDRTEKMK 540 Query: 541 EIVGWMPLMAAQKDFFWEALDMLQRAEGGGGGVGPPAPET 580 EIVGWMPLMAAQKDFFWEALDMLQRAEGGGGGVGPPAPET Sbjct: 541 EIVGWMPLMAAQKDFFWEALDMLQRAEGGGGGVGPPAPET 580 >gi|11024696 F-box only protein 24 isoform 2 [Homo sapiens] Length = 318 Score = 607 bits (1564), Expect = e-173 Identities = 303/318 (95%), Positives = 303/318 (95%), Gaps = 14/318 (4%) Query: 1 MGEKAVPLLRRRRVKRSCPSCGSELGVEEKRGKGNPISIQLFPPELVEHIISFLPVRDLV 60 MGEKAVPLLRRRRVKRSCPSCGSELGVEEKRGKGNPISIQLFPPELVEHIISFLPVRDLV Sbjct: 1 MGEKAVPLLRRRRVKRSCPSCGSELGVEEKRGKGNPISIQLFPPELVEHIISFLPVRDLV 60 Query: 61 ALGQTCRYFHEVCDGEGVWRRICRRLSPRLQDQGSGVRPWKRAAILNYTKGLYFQAFGGR 120 ALGQTCRYFHEVCDGEGVWRRICRRLSPRLQDQ TKGLYFQAFGGR Sbjct: 61 ALGQTCRYFHEVCDGEGVWRRICRRLSPRLQDQD--------------TKGLYFQAFGGR 106 Query: 121 RRCLSKSVAPLLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSTLGQMQWKRACRYVVL 180 RRCLSKSVAPLLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSTLGQMQWKRACRYVVL Sbjct: 107 RRCLSKSVAPLLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSTLGQMQWKRACRYVVL 166 Query: 181 CRGAKDFASDPRCDTVYRKYLYVLATREPQEVVGTTSSRACDCVEVYLQSSGQRVFKMTF 240 CRGAKDFASDPRCDTVYRKYLYVLATREPQEVVGTTSSRACDCVEVYLQSSGQRVFKMTF Sbjct: 167 CRGAKDFASDPRCDTVYRKYLYVLATREPQEVVGTTSSRACDCVEVYLQSSGQRVFKMTF 226 Query: 241 HHSMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPH 300 HHSMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPH Sbjct: 227 HHSMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPH 286 Query: 301 LRVACMTSNQSSTLYVTD 318 LRVACMTSNQSSTLYVTD Sbjct: 287 LRVACMTSNQSSTLYVTD 304 >gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens] Length = 4861 Score = 50.4 bits (119), Expect = 4e-06 Identities = 46/162 (28%), Positives = 76/162 (46%), Gaps = 16/162 (9%) Query: 288 QLALRKVSHYLPHLRVACMTSNQSS---TLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDP 344 Q L+K++ + PH + ++S++ S TL T +G V+ G Y G L + Sbjct: 443 QSTLKKLT-FEPHRSIKKVSSSKGSDGHTLAFTTEGEVFS--WGDGDY----GKLGHGNS 495 Query: 345 LDQQMPLALSLP--AKILFC-ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPT 401 Q+ P + P K++ C + GY H V E G ++ G +G+LG GD R PT Sbjct: 496 STQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPT 555 Query: 402 QVCYLQRPITLWCGLNHSLVLSQSSEFSKELLGCGCGAGGRL 443 V + + CG +H++ LS+ + + G G G+L Sbjct: 556 LVKDISNVGEVSCGSSHTIALSKD---GRTVWSFGGGDNGKL 594 Score = 43.1 bits (100), Expect = 7e-04 Identities = 22/68 (32%), Positives = 40/68 (58%), Gaps = 2/68 (2%) Query: 358 KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQ--RPITLWCG 415 +++ + G+ H +V G++F GN YG+LG G+ ++ P +V L+ + + CG Sbjct: 4135 EVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACG 4194 Query: 416 LNHSLVLS 423 LNH+L +S Sbjct: 4195 LNHTLAVS 4202 Score = 37.4 bits (85), Expect = 0.038 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Query: 368 HLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQ--RPITLWCGLNHSLVLSQS 425 H + E G +F G+ YG+LG G+ + P Q+ LQ + + CG HS V++ Sbjct: 4093 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSD 4152 Query: 426 SEFSKELLGCGCGAGGRL 443 +L G G GRL Sbjct: 4153 G----KLFTFGNGDYGRL 4166 >gi|4557445 regulator of chromosome condensation and BTB domain containing protein 2 [Homo sapiens] Length = 551 Score = 50.1 bits (118), Expect = 6e-06 Identities = 43/163 (26%), Positives = 77/163 (47%), Gaps = 9/163 (5%) Query: 243 SMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPHLR 302 +++ KQ++ V + +L+L T +G++++ N + S Q R+V+ L + Sbjct: 148 NLSNKQVIEVACGSYHSLVL-TSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKV 206 Query: 303 VACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMP--LALSLPAKIL 360 V + Q + V D G VY + G L + +Q P +A ++ Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGN------GQLGLGNSGNQPTPCRVAALQGIRVQ 260 Query: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQV 403 A GY H ++ + G+++ G N YGQLGTG+K ++ PT V Sbjct: 261 RVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPV 303 Score = 36.2 bits (82), Expect = 0.085 Identities = 48/216 (22%), Positives = 93/216 (43%), Gaps = 15/216 (6%) Query: 243 SMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPHLR 302 S+ K+I + + ++L T EG++++ N + L +S L + + Sbjct: 94 SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQ 153 Query: 303 VACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMPLALS--LPAKIL 360 V + +L +T G V+ + G + + ++Q +P ++ L K++ Sbjct: 154 VIEVACGSYHSLVLTSDGEVFAWGYNNS------GQVGSGSTVNQPIPRRVTGCLQNKVV 207 Query: 361 FC-ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQ--RPITLWCGLN 417 A G V + G +++ G N GQLG G+ ++ P +V LQ R + CG Sbjct: 208 VTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYA 267 Query: 418 HSLVLSQSSEFSKELLGCGCGAGGRLPGWPKGSASF 453 H+LVL+ ++ G + G+L K + S+ Sbjct: 268 HTLVLTDEG----QVYAWGANSYGQLGTGNKSNQSY 299 >gi|209969703 regulator of chromosome condensation 2 [Homo sapiens] Length = 522 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 6/87 (6%) Query: 359 ILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDR-GEPTQVCYLQRPIT-LWCGL 416 I+ A G NH + E G +F G N+ GQLG G++ D P Q+ Y +PIT + CG Sbjct: 204 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA 263 Query: 417 NHSLVLSQSSEFSKELLGCGCGAGGRL 443 S+++ + L GC G+L Sbjct: 264 EFSMIM----DCKGNLYSFGCPEYGQL 286 Score = 32.7 bits (73), Expect = 0.94 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 2/60 (3%) Query: 368 HLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRP--ITLWCGLNHSLVLSQS 425 H L+ G+++ G N GQLG GD P + L ++ CG NH+L L+++ Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220 Score = 32.0 bits (71), Expect = 1.6 Identities = 54/217 (24%), Positives = 86/217 (39%), Gaps = 51/217 (23%) Query: 261 LLLTEEGKIYSLVVNET-QLDQPRSYTVQLALRKVSHYLPHLRVACMTSNQSSTLYVTDQ 319 LL+T EGK++S NE QL T ++ ++ L H + ++ TL +T+ Sbjct: 163 LLITTEGKLWSWGRNEKGQLG--HGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220 Query: 320 GGVYFEVHTPGVYRDLFGTLQAFDPLDQQMPLALSLPAKILF-------CALGYNHLGLV 372 G V+ + G L + D A+ PA+I++ A G ++ Sbjct: 221 GSVF------AFGENKMGQLGLGNQTD-----AVPSPAQIMYNGQPITKMACGAEFSMIM 269 Query: 373 DEFGRIFMQGNNRYGQLG---TGDKMDRGEPTQV-CYL-QRPITLW-------------- 413 D G ++ G YGQLG G + R + + C L R + ++ Sbjct: 270 DCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPN 329 Query: 414 -------CGLNHSLVLSQSSEFSKELLGCGCGAGGRL 443 CG NH+LVL + K + G G GRL Sbjct: 330 VVVRDVACGANHTLVL----DSQKRVFSWGFGGYGRL 362 >gi|29789090 regulator of chromosome condensation 2 [Homo sapiens] Length = 522 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 6/87 (6%) Query: 359 ILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDR-GEPTQVCYLQRPIT-LWCGL 416 I+ A G NH + E G +F G N+ GQLG G++ D P Q+ Y +PIT + CG Sbjct: 204 IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA 263 Query: 417 NHSLVLSQSSEFSKELLGCGCGAGGRL 443 S+++ + L GC G+L Sbjct: 264 EFSMIM----DCKGNLYSFGCPEYGQL 286 Score = 32.7 bits (73), Expect = 0.94 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 2/60 (3%) Query: 368 HLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRP--ITLWCGLNHSLVLSQS 425 H L+ G+++ G N GQLG GD P + L ++ CG NH+L L+++ Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220 Score = 32.0 bits (71), Expect = 1.6 Identities = 54/217 (24%), Positives = 86/217 (39%), Gaps = 51/217 (23%) Query: 261 LLLTEEGKIYSLVVNET-QLDQPRSYTVQLALRKVSHYLPHLRVACMTSNQSSTLYVTDQ 319 LL+T EGK++S NE QL T ++ ++ L H + ++ TL +T+ Sbjct: 163 LLITTEGKLWSWGRNEKGQLG--HGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220 Query: 320 GGVYFEVHTPGVYRDLFGTLQAFDPLDQQMPLALSLPAKILF-------CALGYNHLGLV 372 G V+ + G L + D A+ PA+I++ A G ++ Sbjct: 221 GSVF------AFGENKMGQLGLGNQTD-----AVPSPAQIMYNGQPITKMACGAEFSMIM 269 Query: 373 DEFGRIFMQGNNRYGQLG---TGDKMDRGEPTQV-CYL-QRPITLW-------------- 413 D G ++ G YGQLG G + R + + C L R + ++ Sbjct: 270 DCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPN 329 Query: 414 -------CGLNHSLVLSQSSEFSKELLGCGCGAGGRL 443 CG NH+LVL + K + G G GRL Sbjct: 330 VVVRDVACGANHTLVL----DSQKRVFSWGFGGYGRL 362 >gi|57242759 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 [Homo sapiens] Length = 531 Score = 45.1 bits (105), Expect = 2e-04 Identities = 45/162 (27%), Positives = 73/162 (45%), Gaps = 7/162 (4%) Query: 243 SMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPHLR 302 ++ KQ+V V + ++ L + G++++ N S Q RKV++ L R Sbjct: 124 NLLIKQVVEVACGSHHSMALAAD-GEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKR 182 Query: 303 VACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMPLALSLPAKILFC 362 V + Q+S++ V D G VY + L P+ ++ S+ + C Sbjct: 183 VVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPV--RVAALHSVCVNQIVC 240 Query: 363 ALGYNH-LGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQV 403 GY H L L DE G ++ G N YGQLGTG+K + P + Sbjct: 241 --GYAHTLALTDE-GLLYAWGANTYGQLGTGNKNNLLSPAHI 279 Score = 43.9 bits (102), Expect = 4e-04 Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 16/156 (10%) Query: 301 LRVACMTSNQSS-TLYVTDQGGVY-FEVHTPGVYRDLFGTLQAFDPLDQQMPLALSLPAK 358 +R AC+ +S LYVTD V+ F ++ Y + GT D +P L Sbjct: 21 IRKACVFGTSASEALYVTDNDEVFVFGLN----YSNCLGT---GDNQSTLVPKKLEGLCG 73 Query: 359 ILFCALGYN---HLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVC---YLQRPITL 412 +L Y H+ L E G ++ G+N Y QLG G P QVC +++ + + Sbjct: 74 KKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEV 133 Query: 413 WCGLNHSLVLSQSSE-FSKELLGCGCGAGGRLPGWP 447 CG +HS+ L+ E F+ CG G P Sbjct: 134 ACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQP 169 >gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo sapiens] Length = 589 Score = 43.5 bits (101), Expect = 5e-04 Identities = 18/46 (39%), Positives = 28/46 (60%) Query: 39 IQLFPPELVEHIISFLPVRDLVALGQTCRYFHEVCDGEGVWRRICR 84 I L P EL +++SFL +DL+ QTCRY+ + + +WR C+ Sbjct: 163 ISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCK 208 >gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo sapiens] Length = 707 Score = 43.5 bits (101), Expect = 5e-04 Identities = 18/46 (39%), Positives = 28/46 (60%) Query: 39 IQLFPPELVEHIISFLPVRDLVALGQTCRYFHEVCDGEGVWRRICR 84 I L P EL +++SFL +DL+ QTCRY+ + + +WR C+ Sbjct: 281 ISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCK 326 >gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo sapiens] Length = 627 Score = 43.5 bits (101), Expect = 5e-04 Identities = 18/46 (39%), Positives = 28/46 (60%) Query: 39 IQLFPPELVEHIISFLPVRDLVALGQTCRYFHEVCDGEGVWRRICR 84 I L P EL +++SFL +DL+ QTCRY+ + + +WR C+ Sbjct: 201 ISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCK 246 >gi|126116565 MYC binding protein 2 [Homo sapiens] Length = 4640 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/77 (37%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Query: 365 GYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPIT-LWCGLNHSLVLS 423 G++H ++ E G ++ G ++GQLG GD RG PT V L P T + G NH+ VL Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAGSNHTAVLL 969 Query: 424 QSSE------FSKELLG 434 + FSK LG Sbjct: 970 MDGQVFTFGSFSKGQLG 986 >gi|42558258 F-box protein 33 [Homo sapiens] Length = 555 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 11/85 (12%) Query: 13 RVKRSCPSCGSELGVEEKRGK----GNPISIQLFPPELVEHIISFLPVRDLVALGQTCRY 68 RV R P GS +RG+ G P EL+ HI SFLP D + +C + Sbjct: 43 RVLRGRPGAGSR-----RRGRMALCGQAAGAASLPSELIVHIFSFLPAPDRLRASASCSH 97 Query: 69 FHEVCDGEGVW--RRICRRLSPRLQ 91 + E +W RIC R+SP Q Sbjct: 98 WRECLFYPALWPQLRICLRVSPAEQ 122 >gi|83035136 F-box protein 31 [Homo sapiens] Length = 539 Score = 42.0 bits (97), Expect = 0.002 Identities = 19/47 (40%), Positives = 26/47 (55%) Query: 38 SIQLFPPELVEHIISFLPVRDLVALGQTCRYFHEVCDGEGVWRRICR 84 S+ PPEL+ I + LP DL +L Q C F + + +WRR CR Sbjct: 66 SLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCR 112 >gi|37620181 hect domain and RLD 4 isoform b [Homo sapiens] Length = 1049 Score = 40.0 bits (92), Expect = 0.006 Identities = 41/150 (27%), Positives = 65/150 (43%), Gaps = 16/150 (10%) Query: 298 LPHLRVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMP-LALSLP 356 +P ++VA + + + +T G ++ G R+ FG L D D+ +P L SL Sbjct: 190 IPFMQVA---AGGAHSFVLTLSGAIF------GWGRNKFGQLGLNDENDRYVPNLLKSLR 240 Query: 357 A-KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPIT--LW 413 + KI++ G +H + + G +F G YGQLG P +V L I + Sbjct: 241 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA 300 Query: 414 CGLNHSLVLSQSSEFSKELLGCGCGAGGRL 443 CG H+ S S + G G G+L Sbjct: 301 CGRQHTSAFVPS---SGRIYSFGLGGNGQL 327 Score = 32.0 bits (71), Expect = 1.6 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 16/140 (11%) Query: 258 RALLLLTEEGKIYSLVVNET-QLDQPRSYTVQLALRKVSHYLPHL---RVACMTSNQSST 313 R + + ++G +Y+ N+ QL +S RK + L + ++ ++ T Sbjct: 44 RHTVFVLDDGTVYTCGCNDLGQLGHEKS-------RKKPEQVVALDAQNIVAVSCGEAHT 96 Query: 314 LYVTDQGGVYFEVHTPGVYRD-LFGTLQAFDPLDQQMPLALSLPAKILFCALGYNHLGLV 372 L + D+G VY G+ D G + + + + + +I+ A GY H + Sbjct: 97 LALNDKGQVY----AWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLAL 152 Query: 373 DEFGRIFMQGNNRYGQLGTG 392 + +F G N+YGQLG G Sbjct: 153 SKASEVFCWGQNKYGQLGLG 172 Score = 30.8 bits (68), Expect = 3.6 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 4/65 (6%) Query: 365 GYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCGLNHSLVL 422 G H V + G ++ G N GQLG + R +P QV L Q + + CG H+L L Sbjct: 42 GLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDAQNIVAVSCGEAHTLAL 99 Query: 423 SQSSE 427 + + Sbjct: 100 NDKGQ 104 >gi|63025188 hect domain and RLD 4 isoform a [Homo sapiens] Length = 1057 Score = 40.0 bits (92), Expect = 0.006 Identities = 41/150 (27%), Positives = 65/150 (43%), Gaps = 16/150 (10%) Query: 298 LPHLRVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMP-LALSLP 356 +P ++VA + + + +T G ++ G R+ FG L D D+ +P L SL Sbjct: 190 IPFMQVA---AGGAHSFVLTLSGAIF------GWGRNKFGQLGLNDENDRYVPNLLKSLR 240 Query: 357 A-KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPIT--LW 413 + KI++ G +H + + G +F G YGQLG P +V L I + Sbjct: 241 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA 300 Query: 414 CGLNHSLVLSQSSEFSKELLGCGCGAGGRL 443 CG H+ S S + G G G+L Sbjct: 301 CGRQHTSAFVPS---SGRIYSFGLGGNGQL 327 Score = 32.0 bits (71), Expect = 1.6 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 16/140 (11%) Query: 258 RALLLLTEEGKIYSLVVNET-QLDQPRSYTVQLALRKVSHYLPHL---RVACMTSNQSST 313 R + + ++G +Y+ N+ QL +S RK + L + ++ ++ T Sbjct: 44 RHTVFVLDDGTVYTCGCNDLGQLGHEKS-------RKKPEQVVALDAQNIVAVSCGEAHT 96 Query: 314 LYVTDQGGVYFEVHTPGVYRD-LFGTLQAFDPLDQQMPLALSLPAKILFCALGYNHLGLV 372 L + D+G VY G+ D G + + + + + +I+ A GY H + Sbjct: 97 LALNDKGQVY----AWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLAL 152 Query: 373 DEFGRIFMQGNNRYGQLGTG 392 + +F G N+YGQLG G Sbjct: 153 SKASEVFCWGQNKYGQLGLG 172 Score = 30.8 bits (68), Expect = 3.6 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 4/65 (6%) Query: 365 GYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCGLNHSLVL 422 G H V + G ++ G N GQLG + R +P QV L Q + + CG H+L L Sbjct: 42 GLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDAQNIVAVSCGEAHTLAL 99 Query: 423 SQSSE 427 + + Sbjct: 100 NDKGQ 104 >gi|126032348 hect domain and RLD 2 [Homo sapiens] Length = 4834 Score = 39.3 bits (90), Expect = 0.010 Identities = 49/221 (22%), Positives = 90/221 (40%), Gaps = 18/221 (8%) Query: 245 TFKQIVLVGQETQRALLLLTEEGKIYSL---VVNETQLDQPRSYTVQLALRKVSHYLPHL 301 T + + L+G E + L +T +GK+Y+ + S + L + H + Sbjct: 3984 TLRPVQLIGGE--QTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVF--I 4039 Query: 302 RVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQMPLALSLPAKILF 361 + + S L ++ +G EV++ G D P D+ + +++ Sbjct: 4040 KKVAVNSGGKHCLALSSEG----EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVD 4095 Query: 362 CALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQ--RPITLWCGLNHS 419 A G H V G ++ G RYG+LG D D+ +P V LQ R + + CG + Sbjct: 4096 VAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDA 4155 Query: 420 LVLSQSSEFSKELLGCGCGAGGRLPGWPKGSASFVKLQVKV 460 L + + + G G G+L +G + K+ +K+ Sbjct: 4156 QTLCLTDD--DTVWSWGDGDYGKL---GRGGSDGCKVPMKI 4191 Score = 36.2 bits (82), Expect = 0.085 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 2/65 (3%) Query: 358 KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCG 415 KI+ A+G H V + G+++ G+N +GQ G G +PT V L Q+ + CG Sbjct: 3258 KIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACG 3317 Query: 416 LNHSL 420 +HS+ Sbjct: 3318 SSHSV 3322 Score = 35.0 bits (79), Expect = 0.19 Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 29/210 (13%) Query: 232 GQRVFKMTFHHSMTFKQIVLVGQETQRALLLLTEEGKIYS----------LVVNETQLDQ 281 G ++ +F +++ +V V + ++L +T EGK+Y+ L ++ + Sbjct: 2977 GSKIKVPSFSETLSALNVVQVAGGS-KSLFAVTVEGKVYACGEATNGRLGLGISSGTVPI 3035 Query: 282 PRSYTVQLALRKVSHYLPHLRVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQA 341 PR T +S Y+ +VA + + +T D +V + G D G L Sbjct: 3036 PRQITA------LSSYVVK-KVAVHSGGRHATALTVDG-----KVFSWGEGDD--GKLGH 3081 Query: 342 FDPLDQQMPLALSL--PAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGE 399 F ++ P + +I A G +H + G ++ G YG+LG GD + + Sbjct: 3082 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLK 3141 Query: 400 PTQVCYL--QRPITLWCGLNHSLVLSQSSE 427 P V L R I + CG + L+ + E Sbjct: 3142 PKMVKVLLGHRVIQVACGSRDAQTLALTDE 3171 Score = 32.7 bits (73), Expect = 0.94 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Query: 358 KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQ--RPITLWCG 415 K++ A G H E G ++ G+N GQLG G P V LQ + + CG Sbjct: 4250 KVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACG 4309 Query: 416 LNHSLVLSQSSEFS 429 H+L S S S Sbjct: 4310 SAHTLAWSTSKPAS 4323 >gi|114796646 regulator of chromosome condensation 1 isoform b [Homo sapiens] Length = 438 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 5/90 (5%) Query: 302 RVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQM-PLALSLPAKIL 360 +V +++ S T +TD G V+ G +RD G + +P+ + M P+ + L ++ Sbjct: 137 KVVQVSAGDSHTAALTDDGRVFLW----GSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVV 192 Query: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLG 390 A G +HL ++ G ++ G GQLG Sbjct: 193 KVASGNDHLVMLTADGDLYTLGCGEQGQLG 222 >gi|114796644 regulator of chromosome condensation 1 isoform a [Homo sapiens] Length = 452 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 5/90 (5%) Query: 302 RVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQM-PLALSLPAKIL 360 +V +++ S T +TD G V+ G +RD G + +P+ + M P+ + L ++ Sbjct: 151 KVVQVSAGDSHTAALTDDGRVFLW----GSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVV 206 Query: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLG 390 A G +HL ++ G ++ G GQLG Sbjct: 207 KVASGNDHLVMLTADGDLYTLGCGEQGQLG 236 >gi|4502801 regulator of chromosome condensation 1 isoform c [Homo sapiens] Length = 421 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 5/90 (5%) Query: 302 RVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQM-PLALSLPAKIL 360 +V +++ S T +TD G V+ G +RD G + +P+ + M P+ + L ++ Sbjct: 120 KVVQVSAGDSHTAALTDDGRVFLW----GSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVV 175 Query: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLG 390 A G +HL ++ G ++ G GQLG Sbjct: 176 KVASGNDHLVMLTADGDLYTLGCGEQGQLG 205 >gi|114796642 regulator of chromosome condensation 1 [Homo sapiens] Length = 421 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 5/90 (5%) Query: 302 RVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQM-PLALSLPAKIL 360 +V +++ S T +TD G V+ G +RD G + +P+ + M P+ + L ++ Sbjct: 120 KVVQVSAGDSHTAALTDDGRVFLW----GSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVV 175 Query: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLG 390 A G +HL ++ G ++ G GQLG Sbjct: 176 KVASGNDHLVMLTADGDLYTLGCGEQGQLG 205 >gi|114796640 regulator of chromosome condensation 1 [Homo sapiens] Length = 421 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 5/90 (5%) Query: 302 RVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQM-PLALSLPAKIL 360 +V +++ S T +TD G V+ G +RD G + +P+ + M P+ + L ++ Sbjct: 120 KVVQVSAGDSHTAALTDDGRVFLW----GSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVV 175 Query: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLG 390 A G +HL ++ G ++ G GQLG Sbjct: 176 KVASGNDHLVMLTADGDLYTLGCGEQGQLG 205 >gi|114796648 regulator of chromosome condensation 1 [Homo sapiens] Length = 421 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 5/90 (5%) Query: 302 RVACMTSNQSSTLYVTDQGGVYFEVHTPGVYRDLFGTLQAFDPLDQQM-PLALSLPAKIL 360 +V +++ S T +TD G V+ G +RD G + +P+ + M P+ + L ++ Sbjct: 120 KVVQVSAGDSHTAALTDDGRVFLW----GSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVV 175 Query: 361 FCALGYNHLGLVDEFGRIFMQGNNRYGQLG 390 A G +HL ++ G ++ G GQLG Sbjct: 176 KVASGNDHLVMLTADGDLYTLGCGEQGQLG 205 >gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo sapiens] Length = 815 Score = 38.5 bits (88), Expect = 0.017 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Query: 365 GYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCGLNHSLVL 422 G H +V +++M G+N +GQLG G K +PT V L ++ CG NH+LV Sbjct: 43 GDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVS 102 Query: 423 SQ 424 ++ Sbjct: 103 TE 104 Score = 37.0 bits (84), Expect = 0.050 Identities = 17/42 (40%), Positives = 22/42 (52%) Query: 356 PAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDR 397 P K+ A G NH + E G ++ G N GQLG GD +R Sbjct: 86 PEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEER 127 Score = 35.0 bits (79), Expect = 0.19 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Query: 358 KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPIT-LWCGL 416 KI + G N + E GR+FM G+N GQ+G + + P QV + +P++ + CG Sbjct: 141 KIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVT-IGKPVSWISCGY 199 Query: 417 NHSLVLSQSSE 427 HS ++ E Sbjct: 200 YHSAFVTTDGE 210 Score = 31.6 bits (70), Expect = 2.1 Identities = 18/84 (21%), Positives = 45/84 (53%), Gaps = 3/84 (3%) Query: 349 MPLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKM--DRGEPTQVCYL 406 +P +++ + + + GY H V G +++ G G+LG +++ + P V + Sbjct: 182 VPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEI 241 Query: 407 -QRPITLWCGLNHSLVLSQSSEFS 429 ++ I + CG H++VL++++ ++ Sbjct: 242 PEKVIQVACGGEHTVVLTENAVYT 265 Score = 31.2 bits (69), Expect = 2.7 Identities = 12/34 (35%), Positives = 21/34 (61%) Query: 359 ILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTG 392 I + + G NH L+ + G ++ G+ R+G+LG G Sbjct: 297 ISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 38.5 bits (88), Expect = 0.017 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Query: 365 GYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCGLNHSLVL 422 G H +V +++M G+N +GQLG G K +PT V L ++ CG NH+LV Sbjct: 43 GDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVS 102 Query: 423 SQ 424 ++ Sbjct: 103 TE 104 Score = 37.0 bits (84), Expect = 0.050 Identities = 17/42 (40%), Positives = 22/42 (52%) Query: 356 PAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDR 397 P K+ A G NH + E G ++ G N GQLG GD +R Sbjct: 86 PEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEER 127 Score = 35.0 bits (79), Expect = 0.19 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Query: 358 KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPIT-LWCGL 416 KI + G N + E GR+FM G+N GQ+G + + P QV + +P++ + CG Sbjct: 141 KIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVT-IGKPVSWISCGY 199 Query: 417 NHSLVLSQSSE 427 HS ++ E Sbjct: 200 YHSAFVTTDGE 210 Score = 31.6 bits (70), Expect = 2.1 Identities = 18/84 (21%), Positives = 45/84 (53%), Gaps = 3/84 (3%) Query: 349 MPLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKM--DRGEPTQVCYL 406 +P +++ + + + GY H V G +++ G G+LG +++ + P V + Sbjct: 182 VPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEI 241 Query: 407 -QRPITLWCGLNHSLVLSQSSEFS 429 ++ I + CG H++VL++++ ++ Sbjct: 242 PEKVIQVACGGEHTVVLTENAVYT 265 Score = 31.2 bits (69), Expect = 2.7 Identities = 12/34 (35%), Positives = 21/34 (61%) Query: 359 ILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTG 392 I + + G NH L+ + G ++ G+ R+G+LG G Sbjct: 297 ISYISCGENHTALITDIGLMYTFGDGRHGKLGLG 330 >gi|13540582 Williams-Beuren syndrome chromosome region 16 [Homo sapiens] Length = 464 Score = 38.5 bits (88), Expect = 0.017 Identities = 19/61 (31%), Positives = 32/61 (52%) Query: 365 GYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCGLNHSLVLSQ 424 G +H + G +F+ G N G LG G D+ P +V P+ + CG++H + L++ Sbjct: 402 GLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAK 461 Query: 425 S 425 S Sbjct: 462 S 462 Score = 38.1 bits (87), Expect = 0.022 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 10/106 (9%) Query: 343 DPLDQQMPLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLG--TGDKMDRGEP 400 +P +PL ++L + G H ++ + +F GNN YGQ G + E Sbjct: 160 EPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSES 219 Query: 401 TQVCYLQ----RPITLWCGLNHSLVLSQSSEFSKELLGCGCGAGGR 442 +V +Q + + + CG +HSL L+ E+ CG GA G+ Sbjct: 220 HRVHRMQDFDGQVVQVACGQDHSLFLTDKG----EVYSCGWGADGQ 261 >gi|7657152 hect domain and RLD 3 [Homo sapiens] Length = 1050 Score = 37.7 bits (86), Expect = 0.029 Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Query: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCGLNHSLVL 422 A G NH + E G ++ G N GQLG + ++ E Q I + CG +HSL L Sbjct: 40 ACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLAL 99 Query: 423 SQSSEFSKELLGCGCGAGGRL 443 S +L G G+ G+L Sbjct: 100 SDRG----QLFSWGAGSDGQL 116 >gi|239750800 PREDICTED: hypothetical protein XP_002347563 [Homo sapiens] Length = 596 Score = 37.4 bits (85), Expect = 0.038 Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 2/65 (3%) Query: 358 KILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCG 415 KI+ A+G H V + G+++ G+N +GQ G G +PT V L Q+ + + CG Sbjct: 109 KIVHVAVGAQHCLAVMDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKIMCVACG 168 Query: 416 LNHSL 420 +HS+ Sbjct: 169 SSHSV 173 >gi|30039692 NIMA-related kinase 8 [Homo sapiens] Length = 692 Score = 36.2 bits (82), Expect = 0.085 Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 15/108 (13%) Query: 338 TLQAFDPLDQQMPLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDR 397 TL PLDQ+ L++ L G H V G + G+N++GQLGT + Sbjct: 551 TLLGSAPLDQEPLLSIDL---------GTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGS 601 Query: 398 GEPTQVCYLQ--RPITLWCGLNHSLVLSQSSEFSKELLGCGCGAGGRL 443 P +V L+ + + CG ++ + S E+ G GA GRL Sbjct: 602 RAPCKVQGLEGIKMAMVACGDAFTVAIGAES----EVYSWGKGARGRL 645 >gi|63054860 RCC1 domain containing 1 [Homo sapiens] Length = 376 Score = 35.8 bits (81), Expect = 0.11 Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 4/80 (5%) Query: 350 PLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRP 409 PLA L A+ L LG H L+D G++F G R+GQLG G EP + LQ Sbjct: 153 PLAPELRARQL--ELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGL 210 Query: 410 I--TLWCGLNHSLVLSQSSE 427 + + G HS+ +S++ + Sbjct: 211 VMAEVAAGGWHSVCVSETGD 230 Score = 32.3 bits (72), Expect = 1.2 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 347 QQMPLALSLP--AKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVC 404 Q P L LP + + + G H +V G ++ G +YGQLG D P +V Sbjct: 288 QPFPALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVE 347 Query: 405 Y 405 Y Sbjct: 348 Y 348 >gi|63054858 RCC1 domain containing 1 [Homo sapiens] Length = 376 Score = 35.8 bits (81), Expect = 0.11 Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 4/80 (5%) Query: 350 PLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRP 409 PLA L A+ L LG H L+D G++F G R+GQLG G EP + LQ Sbjct: 153 PLAPELRARQL--ELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGL 210 Query: 410 I--TLWCGLNHSLVLSQSSE 427 + + G HS+ +S++ + Sbjct: 211 VMAEVAAGGWHSVCVSETGD 230 Score = 32.3 bits (72), Expect = 1.2 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 347 QQMPLALSLP--AKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVC 404 Q P L LP + + + G H +V G ++ G +YGQLG D P +V Sbjct: 288 QPFPALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVE 347 Query: 405 Y 405 Y Sbjct: 348 Y 348 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.139 0.438 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,150,759 Number of Sequences: 37866 Number of extensions: 1131687 Number of successful extensions: 2993 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 2818 Number of HSP's gapped (non-prelim): 200 length of query: 580 length of database: 18,247,518 effective HSP length: 108 effective length of query: 472 effective length of database: 14,157,990 effective search space: 6682571280 effective search space used: 6682571280 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.