BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|157427659 coiled-coil domain containing 70 precursor [Homo sapiens] (233 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|157427659 coiled-coil domain containing 70 precursor [Homo sa... 496 e-141 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 91 1e-18 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 88 5e-18 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 85 5e-17 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 85 5e-17 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 85 5e-17 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 79 3e-15 gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 79 3e-15 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 77 1e-14 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 69 4e-12 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 64 1e-10 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 61 7e-10 gi|239748997 PREDICTED: hypothetical protein XP_002346878 [Homo ... 58 6e-09 gi|239743019 PREDICTED: hypothetical protein XP_002342720 [Homo ... 58 6e-09 gi|148746195 trichohyalin [Homo sapiens] 58 6e-09 gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 57 1e-08 gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 57 1e-08 gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 57 1e-08 gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 57 1e-08 gi|221219020 NYD-SP11 protein [Homo sapiens] 52 3e-07 gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 47 1e-05 gi|95147555 microtubule-associated protein 1A [Homo sapiens] 44 9e-05 gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 41 8e-04 gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 41 0.001 gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 40 0.002 gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 39 0.003 gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 39 0.003 gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 39 0.005 gi|150170670 piccolo isoform 2 [Homo sapiens] 39 0.005 gi|150378539 piccolo isoform 1 [Homo sapiens] 39 0.005 >gi|157427659 coiled-coil domain containing 70 precursor [Homo sapiens] Length = 233 Score = 496 bits (1276), Expect = e-141 Identities = 233/233 (100%), Positives = 233/233 (100%) Query: 1 MATPPFRLIRKMFSFKVSRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMKIFRE 60 MATPPFRLIRKMFSFKVSRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMKIFRE Sbjct: 1 MATPPFRLIRKMFSFKVSRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMKIFRE 60 Query: 61 KIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKT 120 KIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKT Sbjct: 61 KIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKT 120 Query: 121 FWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWED 180 FWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWED Sbjct: 121 FWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWED 180 Query: 181 KTSLWEEENALWEEERAFWMENNGHIAGEQMLEDGPHNANRGQRLLAFSRGRA 233 KTSLWEEENALWEEERAFWMENNGHIAGEQMLEDGPHNANRGQRLLAFSRGRA Sbjct: 181 KTSLWEEENALWEEERAFWMENNGHIAGEQMLEDGPHNANRGQRLLAFSRGRA 233 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 90.5 bits (223), Expect = 1e-18 Identities = 45/179 (25%), Positives = 98/179 (54%), Gaps = 22/179 (12%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEE 96 R+KK+ + + + E+M+ EK+++ E+MW K+ ++ WE+E WE+ Sbjct: 594 REKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM---WEQEEKMWEQ 650 Query: 97 EKTFWKEEK------SFWEMEK-----SFREEEKTFWKKYRTFWK---EDKAFW-----K 137 E+ W++++ WE EK +E+E+ W++ + K ++K W + Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710 Query: 138 EDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 E+ ++ ER++ + +E++ + E+E+ + +E + E E+ +WE + +WE+E +WE++R Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769 Score = 86.7 bits (213), Expect = 2e-17 Identities = 47/162 (29%), Positives = 88/162 (54%), Gaps = 15/162 (9%) Query: 46 QEEKAFREEMKIFR--EKIEDFREEMWTFRGKI---HAFRGQILGFWEEERPFWEEEKTF 100 ++EK +E KI+ EKI D +EEMW K+ R Q WE+E ++E+ Sbjct: 502 EQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560 Query: 101 WKEEKSFWEMEKSFREEEKTFWKKYRTFWKED------KAFWKEDNALWERDRNLLQEDK 154 W +E+ MEK +E+EK W + +E+ K +E+ + E++ + ++++ Sbjct: 561 WDQEE---RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617 Query: 155 ALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 + E+E+ +W +E + E E+ +WE + +WE+E +WE++R Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659 Score = 82.8 bits (203), Expect = 2e-16 Identities = 44/184 (23%), Positives = 92/184 (50%), Gaps = 26/184 (14%) Query: 38 QKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPF---- 93 Q++ M K +E +EE + ++++ + +E++W + + Q WE+E Sbjct: 469 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW----EQEKMQEQEEKIWEQEEKIRDQE 524 Query: 94 --WEEEKTFWKEEK------SFWEMEKSFREEEKTFWKKYRTFWK----EDKAFW----- 136 W +EK W++EK WE E+ R++E+ W + K ++K W Sbjct: 525 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK 584 Query: 137 -KEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 +E+ + ER++ + +E++ + E+E+ + +E + E E+ +WE + + E+E +WE+E Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644 Query: 196 RAFW 199 W Sbjct: 645 EKMW 648 Score = 77.4 bits (189), Expect = 1e-14 Identities = 43/189 (22%), Positives = 99/189 (52%), Gaps = 10/189 (5%) Query: 34 PSIRQKKLMHKL--QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEER 91 P ++ L ++ QEE+ +E KI +++ + +R+E R + R Q W +E+ Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE-RLREQEGKMREQEEKMWRQEK 321 Query: 92 PFWEEEKTF------WKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWER 145 E+EK +E+K E E+ +E+E+ W++ ++++ W+++ LWE+ Sbjct: 322 RLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381 Query: 146 DRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGH 205 ++ + ++++ + ++E+ +W ++ L E E+ + E + +WE+ + EE++ E Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQE-KMWEQVEKMREEKKMQEQEKKTR 440 Query: 206 IAGEQMLED 214 E+M E+ Sbjct: 441 DQEEKMQEE 449 Score = 77.4 bits (189), Expect = 1e-14 Identities = 45/163 (27%), Positives = 83/163 (50%), Gaps = 19/163 (11%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFW------EEEKT 99 QEEK EE RE+ + REE T R + + Q WE+E W E+++ Sbjct: 442 QEEKMQEEER--IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499 Query: 100 FWKEEK------SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQED 153 W++EK WE E+ R++E+ W + + W+++K +ED +WE++ + ++ Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEE-MWGQEKKMWRQEKMREQEDQ-MWEQEEKMRDQE 557 Query: 154 KALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 + +W++E+ + E+ E EK W+ + + EEE E++ Sbjct: 558 QKMWDQEERM---EKKTQEQEKKTWDQEEKMREEERMREREKK 597 Score = 73.6 bits (179), Expect = 1e-13 Identities = 41/173 (23%), Positives = 93/173 (53%), Gaps = 14/173 (8%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFRE--KIEDFREEMWTFRGKIHAFRGQILGFWEE---E 90 +R+++ + QEEK +R+E ++ + K+ + E+MW ++ ++ +E + Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340 Query: 91 RPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWK-------EDNALW 143 + E+E+ ++E+ WE E+ RE+E+ W++ W+++K + ++ +W Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400 Query: 144 ERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 E+D L ++++ + E+EK +W + + E EK + E + ++E + EEER Sbjct: 401 EQDERLREKEERMREQEK-MWEQVEKMRE-EKKMQEQEKKTRDQEEKMQEEER 451 Score = 72.8 bits (177), Expect = 2e-13 Identities = 54/205 (26%), Positives = 96/205 (46%), Gaps = 36/205 (17%) Query: 46 QEEKAFREEMKIFRE---------KIEDFREEMWT----FRGKIHAFRGQILGFWE---- 88 QEEK +R+E +++ + K+ D E MW R K R Q WE Sbjct: 367 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK-MWEQVEK 425 Query: 89 --EERPFWEEEKTF------WKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDN 140 EE+ E+EK +EE+ E EK REEE+T ++ K+++ W+++ Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485 Query: 141 ALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWM 200 W++ R L ++ + LWE+EK + E E+ +WE + + ++E +W +E+ W Sbjct: 486 KEWQQQR-LPEQKEKLWEQEK--------MQEQEEKIWEQEEKIRDQEE-MWGQEKKMWR 535 Query: 201 ENNGHIAGEQMLEDGPHNANRGQRL 225 + +QM E ++ Q++ Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKM 560 Score = 72.8 bits (177), Expect = 2e-13 Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 19/157 (12%) Query: 44 KLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKE 103 K++EE++ RE K RE+ E RE+ + + + Q WE+E WE+E+ W++ Sbjct: 708 KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767 Query: 104 EKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLL-QEDKALWEEEKA 162 ++ + EK W+ +K +E +WE++ + QE+K +EEK Sbjct: 768 QRLPEQKEK---------------LWEHEK--MQEQEKIWEQEEKMRDQEEKMRGQEEKM 810 Query: 163 LWVEERALLEGEKALWEDKTSLWEEENALWEEERAFW 199 EE+ + EK +W + +W +E +W +E W Sbjct: 811 RGQEEKMRGQEEK-MWGQEEKMWGQEEKMWGQEEKMW 846 Score = 72.0 bits (175), Expect = 4e-13 Identities = 45/193 (23%), Positives = 91/193 (47%), Gaps = 25/193 (12%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEE-----EKTF 100 Q+EK + E +EK+++ E++W + Q W++E+ EE EK Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM 722 Query: 101 WKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEE 160 +EE+ E E+ +E+E+ ++ W++++ W+++ +WE+ R Q++K LWE E Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK-LWEHE 781 Query: 161 KA-----LWVEERALLEGEKAL---------WEDKT-----SLWEEENALWEEERAFWME 201 K +W +E + + E+ + E+K +W +E +W +E W + Sbjct: 782 KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ 841 Query: 202 NNGHIAGEQMLED 214 E+ +E+ Sbjct: 842 EEKMWGQEEKMEE 854 Score = 70.1 bits (170), Expect = 2e-12 Identities = 37/177 (20%), Positives = 85/177 (48%), Gaps = 21/177 (11%) Query: 32 SSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEER 91 S + K+L KL+ K +++ +EEMW ++ E+E+ Sbjct: 242 SEIQLNVKELKRKLERAKFLLPQVQT-----NTLQEEMWRQEEELR----------EQEK 286 Query: 92 PFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAF------WKEDNALWER 145 ++E+ W++E+ E E RE+E+ W++ + +++K +E L E+ Sbjct: 287 KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346 Query: 146 DRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMEN 202 + + ++++ +WE+E+ + +E + E+ LWE + + E+E + ++E W ++ Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 403 Score = 54.3 bits (129), Expect = 9e-08 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 10/129 (7%) Query: 34 PSIRQKKLMH-KLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERP 92 P ++K H K+QE++ E+ + R++ E R + RG+ RGQ W +E Sbjct: 771 PEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830 Query: 93 FWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQE 152 W +E+ W +E+ W E+ E+ + +E+K +E+ + ++ QE Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQ---------GQEEKMREQEEKMRGQEEKMREQE 881 Query: 153 DKALWEEEK 161 +K +EEK Sbjct: 882 EKMRGQEEK 890 Score = 32.3 bits (72), Expect = 0.36 Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 7/78 (8%) Query: 46 QEEKAFREEMKIF--REKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKE 103 QEEK + +E K++ EK+ E+MW G+ ++ G +EE+ +EEK +E Sbjct: 820 QEEKMWGQEEKMWGQEEKMWGQEEKMW---GQEEKMEEKMQG--QEEKMREQEEKMRGQE 874 Query: 104 EKSFWEMEKSFREEEKTF 121 EK + EK +EEK + Sbjct: 875 EKMREQEEKMRGQEEKIY 892 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 88.2 bits (217), Expect = 5e-18 Identities = 50/181 (27%), Positives = 94/181 (51%), Gaps = 17/181 (9%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFW------EEEKT 99 QEEK EE RE+ + REE T R + + Q WE+E W E+++ Sbjct: 384 QEEKMQEEER--IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441 Query: 100 FWKEEK------SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQED 153 W++EK WE E+ R++E+ W + + W+++K +ED +WE++ + ++ Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEE-MWGQEKKMWRQEKMREQEDQ-MWEQEEKMRDQE 499 Query: 154 KALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLE 213 + +W++E+ +W ++ L E E+ + E K +W++E + EE++ E E+M E Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQK-KMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558 Query: 214 D 214 + Sbjct: 559 E 559 Score = 84.3 bits (207), Expect = 8e-17 Identities = 41/151 (27%), Positives = 89/151 (58%), Gaps = 3/151 (1%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 QE+K ++E K++R++ E RE+ R + R Q E+E+ E+EK +E+K Sbjct: 246 QEKKIRKQEEKMWRQE-ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL-REQK 303 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E+ +E+E+ W++ ++++ W+++ LWE+++ + ++++ + ++E+ +W Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 363 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEER 196 ++ L E E+ + E + +WE+E + EEER Sbjct: 364 QDERLREKEERMREQE-KMWEQEEKMQEEER 393 Score = 83.2 bits (204), Expect = 2e-16 Identities = 39/172 (22%), Positives = 88/172 (51%), Gaps = 2/172 (1%) Query: 44 KLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKE 103 K++EE+ RE K RE+ E RE+ + + R Q WE+E E+E+ W++ Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614 Query: 104 EKSFWEMEK--SFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEK 161 E+ WE E+ +E+E+ W++ ++++ W+++ + E++ + ++++ + +E+ Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674 Query: 162 ALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLE 213 + +E + E+ + E + + +E +W +E W + E+M E Sbjct: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE 726 Score = 81.6 bits (200), Expect = 5e-16 Identities = 42/154 (27%), Positives = 88/154 (57%), Gaps = 10/154 (6%) Query: 46 QEEKAFREEMKIFREKIEDFREE--MWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKE 103 QEE+ + ++ ++ REK E RE+ MW K+ + E+E+ W++E+ +E Sbjct: 505 QEERMWEQDERL-REKEERMREQKKMWQQEEKMREEKKT----QEQEKKTWDQEEKM-RE 558 Query: 104 EKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKAL 163 E+ E EK REEE+ ++ ++++ +++ +WE++ + ++++ +WE+E+ + Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618 Query: 164 W--VEERALLEGEKALWEDKTSLWEEENALWEEE 195 W EE + E E+ +WE + + E+E +WE+E Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652 Score = 81.3 bits (199), Expect = 7e-16 Identities = 46/176 (26%), Positives = 89/176 (50%), Gaps = 8/176 (4%) Query: 38 QKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEE 97 Q++ M K +E +EE + ++++ + +E++W + + Q WE+E ++E Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW----EQEKMQEQEEKIWEQEEKIRDQE 466 Query: 98 KTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALW 157 + W +EK W EK RE+E W++ +++ W ++ +WE+D L ++++ + Sbjct: 467 E-MWGQEKKMWRQEK-MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM- 523 Query: 158 EEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLE 213 E+K +W +E + E EK E + W++E + EEER E E M E Sbjct: 524 REQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578 Score = 80.5 bits (197), Expect = 1e-15 Identities = 48/189 (25%), Positives = 91/189 (48%), Gaps = 26/189 (13%) Query: 46 QEEKAFREEMKIFR--EKIEDFREEMWTFRGKI---HAFRGQILGFWEEERPFWEEEKTF 100 ++EK +E KI+ EKI D +EEMW K+ R Q WE+E ++E+ Sbjct: 444 EQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502 Query: 101 WKEEKSFWEMEKSFRE------EEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDK 154 W +E+ WE ++ RE E+K W++ +E+K +++ W+++ + +E++ Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKM-REEKKTQEQEKKTWDQEEKMREEER 561 Query: 155 -------------ALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWME 201 + E+E+ + +E + E E+ +WE + + E+E +WE+E W + Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621 Query: 202 NNGHIAGEQ 210 EQ Sbjct: 622 EEEDKMQEQ 630 Score = 77.0 bits (188), Expect = 1e-14 Identities = 47/189 (24%), Positives = 94/189 (49%), Gaps = 24/189 (12%) Query: 46 QEEKAFREEMKIFRE---------KIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEE 96 QEEK +R+E +++ + K+ D E MW ++ ++ E+ WE+ Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM----REQEKMWEQ 384 Query: 97 EKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKAL 156 E+ +EE+ E EK REEE+T ++ K+++ W+++ W++ R L ++ + L Sbjct: 385 EEKMQEEER-IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR-LPEQKEKL 442 Query: 157 WEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLEDGP 216 WE+EK + E E+ +WE + + ++E +W +E+ W + +QM E Sbjct: 443 WEQEK--------MQEQEEKIWEQEEKIRDQEE-MWGQEKKMWRQEKMREQEDQMWEQEE 493 Query: 217 HNANRGQRL 225 ++ Q++ Sbjct: 494 KMRDQEQKM 502 Score = 77.0 bits (188), Expect = 1e-14 Identities = 39/187 (20%), Positives = 92/187 (49%), Gaps = 5/187 (2%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWE- 95 R+KK+ + + + E+M+ EK+ + E+MW K+ ++ WE+E WE Sbjct: 565 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM---WEQEEKMWEQ 621 Query: 96 -EEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDK 154 EE ++E+ WE E+ +E+E+ W++ ++++ +++ + ++ + ++++ Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681 Query: 155 ALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLED 214 + +E+ + +E + E+ +W + +W +E +W +E E E+M E Sbjct: 682 KMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQER 741 Query: 215 GPHNANR 221 P + R Sbjct: 742 LPEHEER 748 Score = 74.7 bits (182), Expect = 6e-14 Identities = 39/181 (21%), Positives = 92/181 (50%), Gaps = 14/181 (7%) Query: 34 PSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPF 93 P ++ L ++ ++ EE++ +KI E+MW ++ E+E Sbjct: 225 PQVQTNTLQEEMWRQE---EELREQEKKIRKQEEKMWRQEERLR----------EQEGKM 271 Query: 94 WEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQED 153 E+E+ ++EK E EK RE+EK ++ + ++++ +++ +WE++ + +++ Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKEL-REQKKLREQEEQMQEQEEKMWEQEEKMREQE 330 Query: 154 KALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLE 213 + +W +E+ LW +E+ + E E+ + + + +WE++ L E+E + E+M E Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE 390 Query: 214 D 214 + Sbjct: 391 E 391 Score = 72.4 bits (176), Expect = 3e-13 Identities = 41/178 (23%), Positives = 91/178 (51%), Gaps = 21/178 (11%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWE 95 +R+++ + QEEK R+E ++ RE+ ++ RE+ R + E+E E Sbjct: 264 LREQEGKMREQEEKMRRQEKRL-REQEKELREQEKELREQKK--------LREQEEQMQE 314 Query: 96 EEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNL------ 149 +E+ W++E+ E E+ +E+ W++ + ++++ ++ +WE+D L Sbjct: 315 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374 Query: 150 LQEDKALWEEEKALWVEER------ALLEGEKALWEDKTSLWEEENALWEEERAFWME 201 ++E + +WE+E+ + EER + E E+ + E + + ++E +WE+E W + Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 85.1 bits (209), Expect = 5e-17 Identities = 50/191 (26%), Positives = 96/191 (50%), Gaps = 18/191 (9%) Query: 36 IRQKKLMHKLQEEKAFREEMKIF-REKIED-----FREEMWTFRGKIHAFRGQILGFWEE 89 IR+++ + QE+K +R+E KI +EKI + +EEMW KIH + W + Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH----EQEEIWRQ 494 Query: 90 ERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNL 149 + E+E+ K+E+ W E+ RE+E+ ++ W++++ +E +W R+ Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI-REQEEMW-REEEK 552 Query: 150 LQEDKALWEEEK------ALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENN 203 + E + +WEEEK +W +E + E E+ +W + + E+E E+E W + Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612 Query: 204 GHIAGEQMLED 214 E+ +++ Sbjct: 613 KIREQEEKIQE 623 Score = 78.6 bits (192), Expect = 4e-15 Identities = 47/181 (25%), Positives = 93/181 (51%), Gaps = 13/181 (7%) Query: 42 MHKLQEEKAFREEMKI--FREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKT 99 +++ QEEK +R+E KI + EKI++ E++ KI R Q +E WE+E+ Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI---REQEEKMRRQEEMMWEKEEK 350 Query: 100 FWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEE 159 ++E+ WE E+ R +E+ W+K ++++ W+++ + E + + +++K +E Sbjct: 351 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 410 Query: 160 EKALWVEERALLEGEK------ALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLE 213 EK EE + E EK +W + + E+E + E+E+ W + E++ E Sbjct: 411 EKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468 Query: 214 D 214 + Sbjct: 469 E 469 Score = 78.2 bits (191), Expect = 6e-15 Identities = 49/209 (23%), Positives = 101/209 (48%), Gaps = 32/209 (15%) Query: 37 RQKKLMH------KLQEEKAFREEMKIFREKIEDFRE----------------EMWTFRG 74 RQK+ MH + QEEK +R+E KI RE+ E RE EMW Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKI-REQEEKIREQEEKMWRQEEKIREQEEMWREEE 551 Query: 75 KIHAF---------RGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKY 125 K+H + Q W +E E+E+ W++E+ E E+ +E+E+ WK+ Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611 Query: 126 RTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLW 185 ++++ +++ + E++ + ++++ E+E+ + +E + E E+ + E + ++W Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671 Query: 186 EEENALWEEERAFWMENNGHIAGEQMLED 214 +E + E+E+ + E+M+++ Sbjct: 672 RQEEKIREQEKKIREQEEKIREQEEMMQE 700 Score = 78.2 bits (191), Expect = 6e-15 Identities = 43/166 (25%), Positives = 89/166 (53%), Gaps = 16/166 (9%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEER---- 91 IR+++ + QEEK +R+E KI RE +EEMW K+H + WEEE+ Sbjct: 519 IREQEEKIREQEEKMWRQEEKI-RE-----QEEMWREEEKMH----EQEKIWEEEKRQEQ 568 Query: 92 --PFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNL 149 W +E+ ++E+ W E+ RE+E+ ++ WK+++ +++ + E++ + Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628 Query: 150 LQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 ++++ + E+E+ +E + E E+ + E + + E+E +W +E Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674 Score = 78.2 bits (191), Expect = 6e-15 Identities = 43/191 (22%), Positives = 97/191 (50%), Gaps = 16/191 (8%) Query: 37 RQKKLMHKLQ----EEKAFREEMKIFR--EKIEDFREEMWTFRGKIHAFRGQILGFWEEE 90 R+++ MH+ + EEK +E K++R EKI + E++W KI E+E Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR----------EQE 597 Query: 91 RPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLL 150 E+E+ WK+E+ E E+ +E+E+ ++ ++++ +++ + E++ + Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657 Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQ 210 ++++ + E+E+ +W +E + E EK + E + + E+E + E+E W + E+ Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717 Query: 211 MLEDGPHNANR 221 +++ R Sbjct: 718 KMQEQEEKMRR 728 Score = 75.5 bits (184), Expect = 4e-14 Identities = 39/156 (25%), Positives = 84/156 (53%), Gaps = 6/156 (3%) Query: 46 QEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHAFRGQILG----FWEEERPFWEEEKT 99 QEEK +R+E KI EK ++ E+MW KI +I E+E E+E+ Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641 Query: 100 FWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEE 159 ++E+ E E+ E+E+ ++ T W++++ +++ + E++ + ++++ + E+ Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701 Query: 160 EKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 E+ +W +E + E E+ + E + + +E +WE+E Sbjct: 702 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737 Score = 74.3 bits (181), Expect = 8e-14 Identities = 39/160 (24%), Positives = 89/160 (55%), Gaps = 8/160 (5%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWE 95 IR+++ + QEEK +++E KI RE+ E +E+ R + R E+E E Sbjct: 593 IREQEEKRQEQEEKMWKQEEKI-REQEEKIQEQEEKIREQEEKIR-------EQEEMTQE 644 Query: 96 EEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKA 155 +E+ ++E+ E E+ +E+E+T W++ +++K +++ + E++ + ++++ Sbjct: 645 QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 704 Query: 156 LWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 +WE+E+ + +E + E E+ + + +WE+E L ++E Sbjct: 705 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744 Score = 72.0 bits (175), Expect = 4e-13 Identities = 41/160 (25%), Positives = 81/160 (50%), Gaps = 14/160 (8%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 QEEK EE +EK ++ +MW KI E+E E+EK W++E+ Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR----------EQEEKIREQEKKMWRQEE 458 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E EK REEEK ++ W++++ +++ +W + + ++++ + ++E+ +W Sbjct: 459 KIHEQEK-IREEEKR--QEQEEMWRQEEKIHEQEE-IWRQKEKMHEQEEKIRKQEEKVWR 514 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGH 205 +E + E E+ + E + +W +E + E+E + E H Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554 Score = 65.1 bits (157), Expect = 5e-11 Identities = 43/185 (23%), Positives = 89/185 (48%), Gaps = 15/185 (8%) Query: 37 RQKKLMHKLQEEKAFREEMKIFRE-KIEDFREEMWTFRGKIHAFRGQILGFWEEER---- 91 RQ+++M + +E+ +EEM +E KI + E+M + R Q EEE+ Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH----EQEKIREQEEKRQEEEKIREQ 422 Query: 92 -PFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKE----DNALWERD 146 E+E W++E+ E E+ RE+EK W++ +++K +E +W ++ Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 482 Query: 147 RNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHI 206 + E + +W +++ + +E + + E+ +W + + E+E + E+E W + Sbjct: 483 EKI-HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541 Query: 207 AGEQM 211 E+M Sbjct: 542 EQEEM 546 Score = 62.8 bits (151), Expect = 2e-10 Identities = 35/177 (19%), Positives = 87/177 (49%), Gaps = 21/177 (11%) Query: 32 SSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEER 91 S + K+L KL+ K + ++ E + +E+ + K+ A Q+ EE Sbjct: 238 SEIQLNVKELKRKLERAKLLLPQQQLQAEA-DHLGKELQSVSAKLQA---QV-----EEN 288 Query: 92 PFW-----EEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERD 146 W ++E+ W++E+ E E+ +E+E+ ++ ++++ +++ +WE++ Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348 Query: 147 RNLLQEDKALWE-------EEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 + ++++ +WE +E+ +W +E + E+ +WE + + E E + E+E+ Sbjct: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405 Score = 38.9 bits (89), Expect = 0.004 Identities = 16/101 (15%), Positives = 47/101 (46%), Gaps = 5/101 (4%) Query: 131 EDKAFW-----KEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLW 185 E+ W +++ +W ++ + + ++ + E+E+ + +E + E E+ + + +W Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345 Query: 186 EEENALWEEERAFWMENNGHIAGEQMLEDGPHNANRGQRLL 226 E+E + +E W + E+M+ + R + ++ Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 386 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 85.1 bits (209), Expect = 5e-17 Identities = 44/163 (26%), Positives = 90/163 (55%), Gaps = 4/163 (2%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHAFRGQILG-FWEEERP 92 IR+++ + QEEK +R+E KI EKI++ EEMW KI + W +E+ Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414 Query: 93 FWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQE 152 E+++ ++E+ W E+ RE E+ + + ++ +E+ + E++ + ++ Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474 Query: 153 DKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 ++ + E+E+ W +E+ LL+ E+ +WE + +W +E +WE+E Sbjct: 475 EEKIQEQEEKTWRQEK-LLKQEEKIWEQEEKMWRQEEKMWEQE 516 Score = 81.6 bits (200), Expect = 5e-16 Identities = 47/203 (23%), Positives = 98/203 (48%), Gaps = 17/203 (8%) Query: 41 LMHKLQEEKAFREEMKIFRE---------KIEDFREEMWTFRGKIH----AFRGQILGFW 87 L+++ QEEK +R+E KI + KI + E+MW K+H R Q W Sbjct: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349 Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAF----WKEDNALW 143 +E E+E+ ++E+ W E+ RE+++ ++ W++++ K +W Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409 Query: 144 ERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENN 203 +++ + ++D+ + E+E+ +W +E + E E+ + + + L E E + EEE + Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469 Query: 204 GHIAGEQMLEDGPHNANRGQRLL 226 E+ +++ R ++LL Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLL 492 Score = 79.3 bits (194), Expect = 3e-15 Identities = 50/201 (24%), Positives = 96/201 (47%), Gaps = 17/201 (8%) Query: 37 RQKKLMHKL------QEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHA----FRGQIL 84 RQ++ MH+ QE+K +R+E KI EKI + E+MW KI + Q Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 Query: 85 GFWEEERPFWEEEKT----FWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDN 140 W +E E+E+ W++EK E ++ RE+E+ W++ + ++ ++ Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448 Query: 141 ALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWM 200 L E + + +E++ + E+E+ + +E + E E+ W + L +EE +WE+E W Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK-IWEQEEKMWR 507 Query: 201 ENNGHIAGEQMLEDGPHNANR 221 + E+ +++ R Sbjct: 508 QEEKMWEQEEKMQEQEEKMQR 528 Score = 79.3 bits (194), Expect = 3e-15 Identities = 45/170 (26%), Positives = 90/170 (52%), Gaps = 6/170 (3%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHA----FRGQILGFWEEER 91 IR++ + QEE+ +R+E KI RE+ E +E+MW K+ R Q W +E Sbjct: 376 IREQDEKIQEQEEEMWRQEEKI-REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434 Query: 92 PFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQ 151 E E+ +E+ E+E+ +EEE+ ++ ++++ +++ W +++ L Q Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494 Query: 152 EDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWME 201 E+K +WE+E+ +W +E + E E+ + E + + +E + E+E W + Sbjct: 495 EEK-IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543 Score = 74.7 bits (182), Expect = 6e-14 Identities = 46/177 (25%), Positives = 89/177 (50%), Gaps = 8/177 (4%) Query: 46 QEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHAF----RGQILGFWEEERPFWEEEKT 99 ++EK +R+E K+ EKI + EEMW KI + Q E E EEE+ Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463 Query: 100 FWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEE 159 ++E+ E+ +E+E+ W++ + +E+K W+++ +W ++ + ++++ + E+ Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK-IWEQEEKMWRQEEKMWEQEEKMQEQ 522 Query: 160 EKALWVEERALLEGEKALWEDKTSLWEEENALWE-EERAFWMENNGHIAGEQMLEDG 215 E+ + +E + E E LW+ + + E+E L E EER + + G E G Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 85.1 bits (209), Expect = 5e-17 Identities = 44/163 (26%), Positives = 90/163 (55%), Gaps = 4/163 (2%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHAFRGQILG-FWEEERP 92 IR+++ + QEEK +R+E KI EKI++ EEMW KI + W +E+ Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414 Query: 93 FWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQE 152 E+++ ++E+ W E+ RE E+ + + ++ +E+ + E++ + ++ Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474 Query: 153 DKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 ++ + E+E+ W +E+ LL+ E+ +WE + +W +E +WE+E Sbjct: 475 EEKIQEQEEKTWRQEK-LLKQEEKIWEQEEKMWRQEEKMWEQE 516 Score = 81.6 bits (200), Expect = 5e-16 Identities = 47/203 (23%), Positives = 98/203 (48%), Gaps = 17/203 (8%) Query: 41 LMHKLQEEKAFREEMKIFRE---------KIEDFREEMWTFRGKIH----AFRGQILGFW 87 L+++ QEEK +R+E KI + KI + E+MW K+H R Q W Sbjct: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349 Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAF----WKEDNALW 143 +E E+E+ ++E+ W E+ RE+++ ++ W++++ K +W Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409 Query: 144 ERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENN 203 +++ + ++D+ + E+E+ +W +E + E E+ + + + L E E + EEE + Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469 Query: 204 GHIAGEQMLEDGPHNANRGQRLL 226 E+ +++ R ++LL Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLL 492 Score = 79.3 bits (194), Expect = 3e-15 Identities = 50/201 (24%), Positives = 96/201 (47%), Gaps = 17/201 (8%) Query: 37 RQKKLMHKL------QEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHA----FRGQIL 84 RQ++ MH+ QE+K +R+E KI EKI + E+MW KI + Q Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 Query: 85 GFWEEERPFWEEEKT----FWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDN 140 W +E E+E+ W++EK E ++ RE+E+ W++ + ++ ++ Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448 Query: 141 ALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWM 200 L E + + +E++ + E+E+ + +E + E E+ W + L +EE +WE+E W Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK-IWEQEEKMWR 507 Query: 201 ENNGHIAGEQMLEDGPHNANR 221 + E+ +++ R Sbjct: 508 QEEKMWEQEEKMQEQEEKMQR 528 Score = 79.3 bits (194), Expect = 3e-15 Identities = 45/170 (26%), Positives = 90/170 (52%), Gaps = 6/170 (3%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHA----FRGQILGFWEEER 91 IR++ + QEE+ +R+E KI RE+ E +E+MW K+ R Q W +E Sbjct: 376 IREQDEKIQEQEEEMWRQEEKI-REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434 Query: 92 PFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQ 151 E E+ +E+ E+E+ +EEE+ ++ ++++ +++ W +++ L Q Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494 Query: 152 EDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWME 201 E+K +WE+E+ +W +E + E E+ + E + + +E + E+E W + Sbjct: 495 EEK-IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543 Score = 74.7 bits (182), Expect = 6e-14 Identities = 46/177 (25%), Positives = 89/177 (50%), Gaps = 8/177 (4%) Query: 46 QEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHAF----RGQILGFWEEERPFWEEEKT 99 ++EK +R+E K+ EKI + EEMW KI + Q E E EEE+ Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463 Query: 100 FWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEE 159 ++E+ E+ +E+E+ W++ + +E+K W+++ +W ++ + ++++ + E+ Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK-IWEQEEKMWRQEEKMWEQEEKMQEQ 522 Query: 160 EKALWVEERALLEGEKALWEDKTSLWEEENALWE-EERAFWMENNGHIAGEQMLEDG 215 E+ + +E + E E LW+ + + E+E L E EER + + G E G Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 79.0 bits (193), Expect = 3e-15 Identities = 46/172 (26%), Positives = 92/172 (53%), Gaps = 16/172 (9%) Query: 37 RQKKLMH-----KLQEEKAFREEMKIF--REKIEDFREEMWTFRGKIHAFRGQILGFWEE 89 RQK+ MH + QEEK +R+E K+ EKI + E+MW KI +I E+ Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR---EQ 535 Query: 90 ERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDK------AFWKEDNALW 143 E E+E+ ++E+ E E+ +E+EK ++ + +E+K +++ +W Sbjct: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 595 Query: 144 ERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 E++ + ++++ + E+E+ +W +E + E E+ + E + + +E +WE+E Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 647 Score = 74.7 bits (182), Expect = 6e-14 Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 17/200 (8%) Query: 37 RQKKLMH---KLQEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHA---FRGQILGFW- 87 RQ++ +H K++EE+ +E+ +++R EKI + +EE+W + K+H R Q W Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE-QEEIWRQKEKMHEQEKIRKQEEKVWR 499 Query: 88 ------EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNA 141 ++E E+E+ W++E+ E E+ RE+E+ ++ ++++ +++ Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559 Query: 142 LWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWME 201 + E+++ QE+K +EEK +E+ + E E+ +WE + + E+E + E+E W + Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEK-IREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618 Query: 202 NNGHIAGEQMLEDGPHNANR 221 E+ +++ R Sbjct: 619 EEKMCEQEEKMQEQEEKMRR 638 Score = 68.6 bits (166), Expect = 4e-12 Identities = 46/192 (23%), Positives = 90/192 (46%), Gaps = 28/192 (14%) Query: 42 MHKLQEEKAFREEMKI------FREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWE 95 +++ QEEK +R+E KI +E+ E RE+ R + R Q WE+E Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353 Query: 96 EEKTFWKEEKSF-------WEMEKSFREEEKTFWKKYRTFWKEDKAFWKE---------- 138 +E+ W++E+ WE E+ RE E+ ++ + +E+K +E Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 413 Query: 139 -DNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDK----TSLWEEENALWE 193 + +W ++ + ++++ + E+EK +W +E + E EK E+K +W +E + E Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473 Query: 194 EERAFWMENNGH 205 +E + + H Sbjct: 474 QEEIWRQKEKMH 485 Score = 57.8 bits (138), Expect = 8e-09 Identities = 34/170 (20%), Positives = 85/170 (50%), Gaps = 14/170 (8%) Query: 32 SSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEER 91 S + K+L KL+ K + ++ E + +E+ + K+ A Q+ EE Sbjct: 238 SEIQLNVKELKRKLERAKLLLPQQQLQAEA-DHLGKELQSVSAKLQA---QV-----EEN 288 Query: 92 PFW-----EEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERD 146 W ++E+ W++E+ E E+ +E+E+ ++ ++++ +++ +WE++ Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348 Query: 147 RNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 + ++++ +WE+E+ + E + E E+ + E + + E+E +EE+ Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398 Score = 56.6 bits (135), Expect = 2e-08 Identities = 28/153 (18%), Positives = 68/153 (44%), Gaps = 25/153 (16%) Query: 87 WEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERD 146 W +E E E+ ++E+ E E+ RE+E+ ++ W++++ +++ +WE++ Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362 Query: 147 RNLLQEDKALWEEEKALWVEERALLEGEK-------------------------ALWEDK 181 + + ++ +WE+E+ + E + E EK +W + Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422 Query: 182 TSLWEEENALWEEERAFWMENNGHIAGEQMLED 214 + E+E + E+E+ W + E++ E+ Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 455 Score = 40.4 bits (93), Expect = 0.001 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 12/86 (13%) Query: 36 IRQKKLMHKLQEEKAFREEMKI--FREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPF 93 IR++K + QEEK + +E KI E +++ E+MW K+ E+E Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM----------CEQEEKM 629 Query: 94 WEEEKTFWKEEKSFWEMEKSFREEEK 119 E+E+ ++E+ WE E R++E+ Sbjct: 630 QEQEEKMRRQEEKMWEQEVRLRQQEE 655 Score = 38.1 bits (87), Expect = 0.007 Identities = 22/89 (24%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Query: 138 EDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERA 197 E+N LW R N QE+K +W +E+ + E + E E+ + E + + E+E + +E Sbjct: 286 EENELWNR-LNQQQEEK-MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343 Query: 198 FWMENNGHIAGEQMLEDGPHNANRGQRLL 226 W + E+M+ + R + ++ Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372 Score = 36.6 bits (83), Expect = 0.019 Identities = 15/87 (17%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Query: 131 EDKAFW-----KEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLW 185 E+ W +++ +W ++ + + ++ + E+E+ + +E + E E+ + + +W Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345 Query: 186 EEENALWEEERAFWMENNGHIAGEQML 212 E+E + +E W + E+M+ Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMM 372 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 79.0 bits (193), Expect = 3e-15 Identities = 51/195 (26%), Positives = 96/195 (49%), Gaps = 23/195 (11%) Query: 45 LQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEE 104 ++EE+ RE K RE+ E RE+ + + R Q WE+E E+E+ W++E Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 Query: 105 KSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKE----DNALWE-----RDRNLLQEDK- 154 + WE E+ E+++ +K + + ++++ KE + +W+ R++ QE+K Sbjct: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 Query: 155 -----ALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWE--------EERAFWME 201 + E+E+ +W +E + E E+ +WE + + E+E + E EE+ +E Sbjct: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 Query: 202 NNGHIAGEQMLEDGP 216 G AGE +D P Sbjct: 181 PAGGEAGEGSPQDNP 195 Score = 54.7 bits (130), Expect = 7e-08 Identities = 36/144 (25%), Positives = 77/144 (53%), Gaps = 11/144 (7%) Query: 46 QEEKAFREEMKIF-REKIEDFREEMWT----FRGKIHAFRGQILGFWEEERPFWEEEKTF 100 QEEK + +E K++ ++++ + +E+MW R K R Q + W++ E++KT Sbjct: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKM--WQQVEKMREKKKT- 115 Query: 101 WKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLL-QEDKALWEE 159 +E+ E E+ +E+E+ W++ ++++ W+++ + E++ + QE+K +E Sbjct: 116 --QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173 Query: 160 EKALWVEERALLEGEKALWEDKTS 183 EK VE GE + ++ T+ Sbjct: 174 EKMRDVEPAGGEAGEGSPQDNPTA 197 Score = 49.7 bits (117), Expect = 2e-06 Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 7/96 (7%) Query: 137 KEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSL-------WEEEN 189 +E+ + ER++ + +E++ + E+E+ + +E + E E+ +WE + + WE+E Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 Query: 190 ALWEEERAFWMENNGHIAGEQMLEDGPHNANRGQRL 225 +WE+E W + E+M E + +R+ Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM 97 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 77.0 bits (188), Expect = 1e-14 Identities = 43/194 (22%), Positives = 102/194 (52%), Gaps = 10/194 (5%) Query: 37 RQKKLMH---KLQEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHA----FRGQILGFW 87 RQ++ +H K++EE+ +E+ +++R EKI + +EE+W + KIH R Q W Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE-QEEIWRQKEKIHEQEEKIRKQEEKMW 560 Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 +E ++E+ ++E+ W E+ RE+E+ ++ ++++ +++ + E++ Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIA 207 + ++++ + E+E+ + +E + E EK + E + + E+E + E+E W + Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680 Query: 208 GEQMLEDGPHNANR 221 E+ +++ R Sbjct: 681 QEEKMQEQEEKMRR 694 Score = 71.2 bits (173), Expect = 7e-13 Identities = 43/179 (24%), Positives = 88/179 (49%), Gaps = 23/179 (12%) Query: 42 MHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFW 101 +++ QEEK +R+E EKI+++ E++ KI E+E E+E+ Sbjct: 355 LNQQQEEKMWRQE-----EKIQEWEEKIQEQEEKIR----------EQEEKIREQEEKMR 399 Query: 102 KEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEK 161 ++E+ WE E+ R +E+ W+K ++++ W+++ + E + + +++K +EEK Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459 Query: 162 ALWVEERALLEGEKA------LWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLED 214 EE + E EK +W + + E+E + E+E W + E++ E+ Sbjct: 460 RQ--EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE 516 Score = 71.2 bits (173), Expect = 7e-13 Identities = 44/182 (24%), Positives = 94/182 (51%), Gaps = 13/182 (7%) Query: 37 RQKKLMH------KLQEEKAFREEMKIF--REKIEDFREEMWTFRGKIHA----FRGQIL 84 RQK+ +H + QEEK +R+E K+ EKI + E++W KI R Q Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599 Query: 85 GFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWE 144 E+E E+E+ ++E+ E E+ +E+E+ ++ +++K +++ + E Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 659 Query: 145 RDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNG 204 ++ + ++++ +WE+E+ + +E + E E+ + + +WE+E L ++E E+ Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM-QEHQE 718 Query: 205 HI 206 H+ Sbjct: 719 HL 720 Score = 59.7 bits (143), Expect = 2e-09 Identities = 34/170 (20%), Positives = 86/170 (50%), Gaps = 14/170 (8%) Query: 32 SSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEER 91 S + K+L KL+ K + ++ E + +E+ + K+ A Q+ EE Sbjct: 299 SEIQLNVKELKRKLERAKLLLPQQQLQAEA-DHLGKELQSVSAKLQA---QV-----EEN 349 Query: 92 PFW-----EEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERD 146 W ++E+ W++E+ E E+ +E+E+ ++ ++++ +++ +WE++ Sbjct: 350 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 409 Query: 147 RNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 + ++++ +WE+E+ + +E + E E+ + E + + E+E +EE+ Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459 Score = 40.4 bits (93), Expect = 0.001 Identities = 16/90 (17%), Positives = 44/90 (48%), Gaps = 9/90 (10%) Query: 117 EEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKA 176 EE W + ++++ W+++ + E + + ++++ + E+E+ + +E + E+ Sbjct: 347 EENELWNRLNQ--QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 404 Query: 177 LWEDKTSL-------WEEENALWEEERAFW 199 +WE + + WE+E + +E W Sbjct: 405 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434 Score = 38.9 bits (89), Expect = 0.004 Identities = 22/89 (24%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Query: 138 EDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERA 197 E+N LW R N QE+K +W +E+ + E + E E+ + E + + E+E + +E Sbjct: 347 EENELWNR-LNQQQEEK-MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 404 Query: 198 FWMENNGHIAGEQMLEDGPHNANRGQRLL 226 W + E+M+ + R + ++ Sbjct: 405 MWEKEEKMRRQEEMMWEKEEKMRRQEEMM 433 Score = 37.4 bits (85), Expect = 0.011 Identities = 15/87 (17%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Query: 131 EDKAFW-----KEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLW 185 E+ W +++ +W ++ + + ++ + E+E+ + +E + E E+ + + +W Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 406 Query: 186 EEENALWEEERAFWMENNGHIAGEQML 212 E+E + +E W + E+M+ Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMM 433 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 68.6 bits (166), Expect = 4e-12 Identities = 36/176 (20%), Positives = 87/176 (49%), Gaps = 1/176 (0%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++EK +E K++R++ E RE+ R + + Q E+E WE+E+ ++E+ Sbjct: 374 EQEKRQEQEAKMWRQE-EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E+ RE+EK ++ ++++ +++ + E++ + +++ + E+E+ + Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLEDGPHNANR 221 +E + E EK + E + + E+E + E+E W + E+ +++ R Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548 Score = 66.6 bits (161), Expect = 2e-11 Identities = 39/184 (21%), Positives = 93/184 (50%), Gaps = 12/184 (6%) Query: 42 MHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFW 101 +++ QEEK +R+E KI +E+ E +E+ R + R Q WE+E +E+ W Sbjct: 282 LNQQQEEKMWRQEEKI-QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 340 Query: 102 KEEKSFWEMEKSFREEEKTFWKKYRTFWKE-----------DKAFWKEDNALWERDRNLL 150 ++E+ E+E+ E+EK ++ + +E + W+++ + E++ + Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400 Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQ 210 ++++ + E+E+ + +E + E E+ + E + + +E + E+E+ + E+ Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460 Query: 211 MLED 214 M+++ Sbjct: 461 MMQE 464 Score = 62.4 bits (150), Expect = 3e-10 Identities = 34/160 (21%), Positives = 84/160 (52%), Gaps = 1/160 (0%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWE 95 IR+++ M + QEEK +E K++ ++ E+ +E+ R + R Q E+E E Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQE-EEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457 Query: 96 EEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKA 155 +E+ ++E+ E E E+E ++ ++++ +++ + E++ + ++++ Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517 Query: 156 LWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 + E+E+ +W +E + E E+ + E + + +E + E+E Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557 Score = 57.8 bits (138), Expect = 8e-09 Identities = 36/198 (18%), Positives = 86/198 (43%), Gaps = 32/198 (16%) Query: 32 SSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFW---- 87 S + K+L KL+ K + ++ E + +E+ + K+ A + + W Sbjct: 226 SEIQLNVKELKRKLERAKLLLPQQQLQAEA-DHLGKELQSVSAKLQA-QVEENELWNRLN 283 Query: 88 -EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERD 146 ++E W +E+ + E+ E E+ RE+E+ ++ W++++ +++ +WE++ Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 343 Query: 147 RNLLQEDKALWEEEK-------------------------ALWVEERALLEGEKALWEDK 181 + + ++ + E+EK +W +E + E E+ + E + Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403 Query: 182 TSLWEEENALWEEERAFW 199 + E+E + E+E W Sbjct: 404 EMMQEQEEKMGEQEEKMW 421 Score = 56.2 bits (134), Expect = 2e-08 Identities = 33/141 (23%), Positives = 72/141 (51%), Gaps = 1/141 (0%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 QEEK R+E KI RE+ + RE+ R + + Q E+E E+E ++E+ Sbjct: 430 QEEKMRRQEEKI-REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E+ RE+EK ++ ++++ +++ +WE++ + ++++ + E+E+ + Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548 Query: 166 EERALLEGEKALWEDKTSLWE 186 +E + E E L + + + E Sbjct: 549 QEEKMREQEVRLRQQEEKMQE 569 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 63.9 bits (154), Expect = 1e-10 Identities = 29/156 (18%), Positives = 82/156 (52%) Query: 40 KLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKT 99 K + ++E+ E+ + RE+ E RE+ R + R Q ++E WE+++ Sbjct: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339 Query: 100 FWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEE 159 W++++ W+ E+ E+E+ K+ K+++ K++ + +++ + ++++ + E+ Sbjct: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ 399 Query: 160 EKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 ++ + ++ + E E+ + E K + ++E + E++ Sbjct: 400 KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435 Score = 58.2 bits (139), Expect = 6e-09 Identities = 35/180 (19%), Positives = 90/180 (50%), Gaps = 7/180 (3%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMW-----TFRGKIHAFRGQILGFWEEE 90 +R+++ + QEE+ +E ++ ++K + +EE R + R Q E+E Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316 Query: 91 RPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLL 150 E+E+ K+E+ WE ++ E+++ WK+ ++++ K++ + +++ + Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376 Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQ 210 ++++ + ++E+ + +E + E ++ + E K + E+E + E++ M GEQ Sbjct: 377 KQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQ--MRKQEEHMGEQ 434 Score = 57.8 bits (138), Expect = 8e-09 Identities = 29/150 (19%), Positives = 79/150 (52%), Gaps = 1/150 (0%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++E+ E+ + +++ E E+ R + Q ++E ++E+ K+E+ Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE 262 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E+ RE+E+ K+ +E++ +++ + E++ + ++++ + E+E+ + Sbjct: 263 QMREQEEQMREQEEQMLKQKEQTEQEEQT-GEQEEQMREQEEQMREQEEQMREQEEQMRE 321 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEE 195 +E + + E+ +WE K +WE++ +W++E Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351 Score = 53.1 bits (126), Expect = 2e-07 Identities = 37/173 (21%), Positives = 83/173 (47%), Gaps = 17/173 (9%) Query: 38 QKKLMHKLQEEKAFREEMKIFREKIEDFRE-EMWTFRGKIHAFRGQILGFWEEERPFWEE 96 QK+ ++E+ R++ + RE+ E RE E + K + + G E+E E+ Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG--EQEEQMREQ 301 Query: 97 EKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNL------- 149 E+ ++E+ E E+ RE+E+ K+ W++ + W++ +W+++ + Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361 Query: 150 -LQEDKALWEE------EKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 QE++ +E E+ + +E + + E+ + E K + E++ + E+E Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE 414 Score = 51.6 bits (122), Expect = 6e-07 Identities = 32/170 (18%), Positives = 87/170 (51%), Gaps = 4/170 (2%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 QEE+ ++E ++ +++ E R++ R + R Q +++ +EE+T ++E+ Sbjct: 239 QEEQVQKQEEQVQKQE-EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG-EQEE 296 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E+ RE+E+ ++ ++++ K++ +WE+ + ++ + +W++E+ + Sbjct: 297 QMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE 356 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLEDG 215 +E + + E+ + + + + ++E + ++E M GEQ + G Sbjct: 357 QEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ--MRKQEEQMGEQKEQMG 404 Score = 49.7 bits (117), Expect = 2e-06 Identities = 20/120 (16%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWK------EDNA 141 ++E E+E+ K+E+ + E+ R++E+ ++ ++++ K ++ Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290 Query: 142 LWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWME 201 E++ + ++++ + E+E+ + +E + E E+ + + + +WE++ +WE++ W + Sbjct: 291 TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ 350 Score = 48.9 bits (115), Expect = 4e-06 Identities = 34/168 (20%), Positives = 80/168 (47%), Gaps = 7/168 (4%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++E RE+ RE+ RE+ G++ GQ+ E+E E+E ++E Sbjct: 147 EQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVR---EQEGQVREQEGQMGEQEG 199 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E+ E+E+ K+ ++++ K++ + E++ + ++++ + ++E+ + Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLE 213 +E + E E+ + E + + +++ +EE+ E EQM E Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE 307 Score = 47.8 bits (112), Expect = 8e-06 Identities = 33/168 (19%), Positives = 81/168 (48%), Gaps = 7/168 (4%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++E RE+ RE+ RE+ G++ GQ+ E+E E+E ++E+ Sbjct: 154 EQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVR---EQEGQMGEQEGQMGEQEE 206 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E+ +++E+ ++ K+++ +++ + +++ + ++++ + ++E+ + Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE 266 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLE 213 +E + E E+ + + K +EE +EE+ E EQM E Sbjct: 267 QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314 Score = 47.0 bits (110), Expect = 1e-05 Identities = 27/164 (16%), Positives = 82/164 (50%), Gaps = 6/164 (3%) Query: 38 QKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEE 97 QK+ ++E+ R++ + E+ E +++ + + R Q E+E E+E Sbjct: 216 QKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE 275 Query: 98 KTFWK------EEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQ 151 + K +E+ E E+ RE+E+ ++ ++++ +++ + +++ + + Sbjct: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335 Query: 152 EDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 + + +WE+++ +W +E + E E+ + + + + ++E + ++E Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379 Score = 43.1 bits (100), Expect = 2e-04 Identities = 29/150 (19%), Positives = 73/150 (48%), Gaps = 7/150 (4%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++E RE+ RE+ RE+ G++ GQ+ E+E E+E ++E Sbjct: 133 EQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVR---EQEGQVREQEGQVREQEG 185 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E E+E ++ ++++ K++ + E++ + ++++ + E+E+ + Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEE 195 +E + + E+ + + + + E+E + E+E Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQE 275 Score = 42.7 bits (99), Expect = 3e-04 Identities = 31/168 (18%), Positives = 79/168 (47%), Gaps = 7/168 (4%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++E RE+ RE+ RE+ G++ GQ+ E+E E+E ++E Sbjct: 140 EQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVR---EQEGQVREQEGQVREQEG 192 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E E+E+ ++ K+++ +++ + +++ + ++++ + ++E+ + Sbjct: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK 252 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLE 213 +E + + E+ + E + + E+E + +++ E EQM E Sbjct: 253 QEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300 Score = 40.0 bits (92), Expect = 0.002 Identities = 35/169 (20%), Positives = 79/169 (46%), Gaps = 8/169 (4%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++E RE+ RE+ RE+ G++ GQ+ E+E E+E ++E Sbjct: 119 EQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVR---EQEGQVREQEGQVREQEG 171 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E RE+E ++ +++ +++ + E++ + ++++ + E+E+ + Sbjct: 172 QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK 231 Query: 166 EERALLEGEKALWEDKTSLW-EEENALWEEERAFWMENNGHIAGEQMLE 213 +E + E E+ + + + + +EE +EE+ E EQML+ Sbjct: 232 QEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280 Score = 38.5 bits (88), Expect = 0.005 Identities = 34/169 (20%), Positives = 78/169 (46%), Gaps = 8/169 (4%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++E RE+ RE+ RE+ G++ GQ+ E+E E+E ++E Sbjct: 112 EQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVR---EQEGQVREQEGQVREQEG 164 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 E E RE+E ++ +++ +++ + E++ + ++++ + ++E+ + Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE 224 Query: 166 EERALLEGEKALWEDKTSLW-EEENALWEEERAFWMENNGHIAGEQMLE 213 +E + + E+ + E + + +EE +EE+ E EQM E Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE 273 Score = 37.0 bits (84), Expect = 0.014 Identities = 40/186 (21%), Positives = 84/186 (45%), Gaps = 9/186 (4%) Query: 39 KKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEK 98 K+L KL+ +K + RE+ RE+ G++ GQ+ E+E E+E Sbjct: 35 KELKRKLETDKIPLPQEGQVREQEGQVREQ----EGQVREQEGQVR---EQEGQVREQEG 87 Query: 99 TFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWE 158 ++E E E RE+E ++ +++ +++ + E++ + +++ + E Sbjct: 88 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147 Query: 159 EEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLEDGPHN 218 +E + +E + E E + E + + E+E + E+E E G + GEQ + G Sbjct: 148 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV-REQEGQM-GEQEGQMGEQE 205 Query: 219 ANRGQR 224 G++ Sbjct: 206 EQMGEQ 211 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 61.2 bits (147), Expect = 7e-10 Identities = 44/170 (25%), Positives = 84/170 (49%), Gaps = 15/170 (8%) Query: 27 RSLAASSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGF 86 R L A + + L+++ QEE+ RE+ + RE+ E RE Q Sbjct: 178 RQLQAEVENNQMLSLLNRRQEER-LREQEERLREQEERLRE--------------QEERL 222 Query: 87 WEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERD 146 E+E E+E+ ++E+ E E+ RE E+ ++ ++++ +++ L E++ Sbjct: 223 CEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQE 282 Query: 147 RNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 L ++++ L E+E+ L +E L E E+ L E + L E+E L E+E+ Sbjct: 283 ERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEK 332 Score = 51.2 bits (121), Expect = 7e-07 Identities = 33/127 (25%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 E+E E+E+ ++E+ E E+ RE+E+ ++ ++++ + + L E++ Sbjct: 203 EQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEE 262 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENAL-WEEERAFWMENNGHI 206 L ++++ L E+E+ L +E L E E+ L E + L E+E L +EER E Sbjct: 263 RLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLRE 322 Query: 207 AGEQMLE 213 E++ E Sbjct: 323 QEERLCE 329 Score = 50.1 bits (118), Expect = 2e-06 Identities = 45/186 (24%), Positives = 88/186 (47%), Gaps = 18/186 (9%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 ++E+ RE+ + RE+ E E+ R Q E+E E+E+ ++E+ Sbjct: 224 EQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEE 283 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDK-----ALWEEE 160 E E+ RE+E+ ++ ++++ +++ L E++ L +++K L EE Sbjct: 284 RLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEV 343 Query: 161 KALWVEER------ALLEGEKALWE-----DKTSLWEEENALWEEERAFWMENNGHIAGE 209 + L +ER LLE E+ L E ++ L +++ LW++E +E + E Sbjct: 344 EKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLREL--E 401 Query: 210 QMLEDG 215 +MLE G Sbjct: 402 RMLELG 407 Score = 47.8 bits (112), Expect = 8e-06 Identities = 38/170 (22%), Positives = 79/170 (46%), Gaps = 5/170 (2%) Query: 61 KIEDFREEMWTFRGKIHAFRGQILGFWEEERPFW----EEEKTFWKEEKSFWEMEKSFRE 116 K+E ++E R ++ + Q+ E + +E+ ++E+ E E+ RE Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLRE 217 Query: 117 EEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKA 176 +E+ ++ ++++ +++ L E++ L + ++ L E+E+ L +E L E E+ Sbjct: 218 QEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEER 277 Query: 177 LWEDKTSLWEEENAL-WEEERAFWMENNGHIAGEQMLEDGPHNANRGQRL 225 L E + L E+E L +EER E E++ E + +RL Sbjct: 278 LHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 327 >gi|239748997 PREDICTED: hypothetical protein XP_002346878 [Homo sapiens] Length = 297 Score = 58.2 bits (139), Expect = 6e-09 Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 5/132 (3%) Query: 91 RPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLL 150 +P EEE++ EE S E S + EEK+ + + E K+ E+ +L +R+L Sbjct: 67 KPQMEEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEERSLQVEERSLQ 126 Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQ 210 E+K+L EE++L VEER+L E +L ++ SL EE L EE +E G Sbjct: 127 VEEKSLQVEERSLQVEERSLQVEEGSLQVEEGSLQVEEGDLQVEEGGLQVEE-----GSL 181 Query: 211 MLEDGPHNANRG 222 +E+G + G Sbjct: 182 QVEEGSLHVEEG 193 Score = 54.7 bits (130), Expect = 7e-08 Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 2/137 (1%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 EEER EE + EE S EKS + EE + + ++ E+++ E+ +L ++ Sbjct: 71 EEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEERSLQVEERSLQVEEK 130 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNG-HI 206 +L E+++L EE++L VEE +L E +L ++ L EE L EE + +E H+ Sbjct: 131 SLQVEERSLQVEERSLQVEEGSLQVEEGSLQVEEGDLQVEEGGLQVEEGSLQVEEGSLHV 190 Query: 207 -AGEQMLEDGPHNANRG 222 G+ +E+G G Sbjct: 191 EEGDLHVEEGGLQVEEG 207 Score = 49.3 bits (116), Expect = 3e-06 Identities = 36/116 (31%), Positives = 57/116 (49%) Query: 89 EERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRN 148 EE E+K+ EE+S E+S + EEK+ + R+ E+++ E+ +L + + Sbjct: 100 EEGSLQVEKKSLQVEERSLQVEERSLQVEEKSLQVEERSLQVEERSLQVEEGSLQVEEGS 159 Query: 149 LLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNG 204 L E+ L EE L VEE +L E +L ++ L EE L EE +E G Sbjct: 160 LQVEEGDLQVEEGGLQVEEGSLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVEEGG 215 Score = 48.5 bits (114), Expect = 5e-06 Identities = 50/206 (24%), Positives = 90/206 (43%), Gaps = 6/206 (2%) Query: 18 SRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIH 77 SR+ GL+ S + S + + + ++EE++ + E + + + E + + + Sbjct: 48 SRFQGLSLLPSCDSKSSASKPQ-----MEEERSLQVEEGSLQVEEGSLQVEEKSLQVEEG 102 Query: 78 AFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWK 137 + + + EER EE++ EEKS E+S + EE++ + + E+ + Sbjct: 103 SLQVEKKSLQVEERSLQVEERSLQVEEKSLQVEERSLQVEERSLQVEEGSLQVEEGSLQV 162 Query: 138 EDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERA 197 E+ L + L E+ +L EE +L VEE L E L ++ +L EE L EE A Sbjct: 163 EEGDLQVEEGGLQVEEGSLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEEGA 222 Query: 198 F-WMENNGHIAGEQMLEDGPHNANRG 222 W G +E+G G Sbjct: 223 CRWRRGAADGGGGLQMEEGGLQVEEG 248 Score = 37.0 bits (84), Expect = 0.014 Identities = 25/82 (30%), Positives = 43/82 (52%) Query: 150 LQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGE 209 ++E+++L EE +L VEE +L EK+L ++ SL E+ +L EER+ +E E Sbjct: 70 MEEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEERSLQVEERSLQVEE 129 Query: 210 QMLEDGPHNANRGQRLLAFSRG 231 + L+ + +R L G Sbjct: 130 KSLQVEERSLQVEERSLQVEEG 151 >gi|239743019 PREDICTED: hypothetical protein XP_002342720 [Homo sapiens] Length = 487 Score = 58.2 bits (139), Expect = 6e-09 Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 5/132 (3%) Query: 91 RPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLL 150 +P EEE++ EE S E S + EEK+ + + E K+ E+ +L +R+L Sbjct: 257 KPQMEEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEERSLQVEERSLQ 316 Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQ 210 E+K+L EE++L VEER+L E +L ++ SL EE L EE +E G Sbjct: 317 VEEKSLQVEERSLQVEERSLQVEEGSLQVEEGSLQVEEGDLQVEEGGLQVEE-----GSL 371 Query: 211 MLEDGPHNANRG 222 +E+G + G Sbjct: 372 QVEEGSLHVEEG 383 Score = 54.7 bits (130), Expect = 7e-08 Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 2/137 (1%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 EEER EE + EE S EKS + EE + + ++ E+++ E+ +L ++ Sbjct: 261 EEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEERSLQVEERSLQVEEK 320 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNG-HI 206 +L E+++L EE++L VEE +L E +L ++ L EE L EE + +E H+ Sbjct: 321 SLQVEERSLQVEERSLQVEEGSLQVEEGSLQVEEGDLQVEEGGLQVEEGSLQVEEGSLHV 380 Query: 207 -AGEQMLEDGPHNANRG 222 G+ +E+G G Sbjct: 381 EEGDLHVEEGGLQVEEG 397 Score = 49.3 bits (116), Expect = 3e-06 Identities = 36/116 (31%), Positives = 57/116 (49%) Query: 89 EERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRN 148 EE E+K+ EE+S E+S + EEK+ + R+ E+++ E+ +L + + Sbjct: 290 EEGSLQVEKKSLQVEERSLQVEERSLQVEEKSLQVEERSLQVEERSLQVEEGSLQVEEGS 349 Query: 149 LLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNG 204 L E+ L EE L VEE +L E +L ++ L EE L EE +E G Sbjct: 350 LQVEEGDLQVEEGGLQVEEGSLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVEEGG 405 Score = 48.5 bits (114), Expect = 5e-06 Identities = 50/206 (24%), Positives = 90/206 (43%), Gaps = 6/206 (2%) Query: 18 SRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIH 77 SR+ GL+ S + S + + + ++EE++ + E + + + E + + + Sbjct: 238 SRFQGLSLLPSCDSKSSASKPQ-----MEEERSLQVEEGSLQVEEGSLQVEEKSLQVEEG 292 Query: 78 AFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWK 137 + + + EER EE++ EEKS E+S + EE++ + + E+ + Sbjct: 293 SLQVEKKSLQVEERSLQVEERSLQVEEKSLQVEERSLQVEERSLQVEEGSLQVEEGSLQV 352 Query: 138 EDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERA 197 E+ L + L E+ +L EE +L VEE L E L ++ +L EE L EE A Sbjct: 353 EEGDLQVEEGGLQVEEGSLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEEGA 412 Query: 198 F-WMENNGHIAGEQMLEDGPHNANRG 222 W G +E+G G Sbjct: 413 CRWRRGAADGGGGLQMEEGGLQVEEG 438 Score = 37.0 bits (84), Expect = 0.014 Identities = 25/82 (30%), Positives = 43/82 (52%) Query: 150 LQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGE 209 ++E+++L EE +L VEE +L EK+L ++ SL E+ +L EER+ +E E Sbjct: 260 MEEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEERSLQVEERSLQVEE 319 Query: 210 QMLEDGPHNANRGQRLLAFSRG 231 + L+ + +R L G Sbjct: 320 KSLQVEERSLQVEERSLQVEEG 341 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 58.2 bits (139), Expect = 6e-09 Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 24/198 (12%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIE----DFREEMWTFRGKIHAFRGQILGFWEEERP 92 RQ++ +EE+ +EE ++ RE+ E RE + K+ Q+LG E+R Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982 Query: 93 FWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFW-----KEDKAFWKEDNAL-WERD 146 E EK + +EE+ E E+ REE + K+ R W K+D+ +E+ L ER+ Sbjct: 983 RQEREKKYREEEELQQEEEQLLREERE---KRRRQEWERQYRKKDELQQEEEQLLREERE 1039 Query: 147 RNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHI 206 + LQE + + EE+ L EE LL E+ E E ER + E Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEER-----------ETRRRQELERQYRKEEELQQ 1088 Query: 207 AGEQMLEDGPHNANRGQR 224 EQ+L + P R +R Sbjct: 1089 EEEQLLREEPEKRRRQER 1106 Score = 49.3 bits (116), Expect = 3e-06 Identities = 53/191 (27%), Positives = 89/191 (46%), Gaps = 34/191 (17%) Query: 35 SIRQKKLMHKLQEEKAFREEM-KIFREK---IEDFREEMWTFRGKIHAFRGQILGFWEEE 90 S +K+L+ + +EEK R+E + FRE+ +++ E+ + + FR + L E+ Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373 Query: 91 RPFWEEE---------KTFWKEEKSF----------WEMEKSFREEEKTFWKKYRTFWKE 131 R F EEE + F KEE+ + ++ FREEE+ ++ R Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER----- 1428 Query: 132 DKAFWKEDNAL--WERDRNLLQEDKALWEEEKALWVEERALL----EGEKALWEDKTSLW 185 D+ F +E+ + ER+R L+E++ L +E + EE LL E + E Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL 1488 Query: 186 EEENALWEEER 196 EEE L +ER Sbjct: 1489 EEEQQLRRQER 1499 Score = 48.5 bits (114), Expect = 5e-06 Identities = 44/164 (26%), Positives = 79/164 (48%), Gaps = 26/164 (15%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEE 96 R++K + + Q+ + E ++ +++ FREE Q L E +R F EE Sbjct: 1388 RERKFLKEEQQLRCQEREQQLRQDRDRKFREEE------------QQLSRQERDRKFREE 1435 Query: 97 EKTFWKEEKSFWEMEKSFREEEKTF-WKKYRTFWKEDKAFW-KEDNALW--ERDRNLLQE 152 E+ ++E+ E+ F EEE+ +++R F +E++ +E+ L ERDR L+E Sbjct: 1436 EQQVRRQER-----ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490 Query: 153 DKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 ++ L +E+ +R E E E + EEE L ++R Sbjct: 1491 EQQLRRQER-----DRKFREQELRSQEPERKFLEEEQQLHRQQR 1529 Score = 47.0 bits (110), Expect = 1e-05 Identities = 47/198 (23%), Positives = 86/198 (43%), Gaps = 21/198 (10%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFR----EEMWTFRGKIHAFRGQILGFWEEERP 92 RQ++ +EE+ +EE ++ RE+ E R E + ++ Q+L E+R Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162 Query: 93 FWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQE 152 E E+ + +EE+ E E+ REE++ ++ ++E++ ++ RD + + Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222 Query: 153 DKALWEEEKALWV----------EERALLEGEKALWEDKTS-------LWEEENALWEEE 195 K WE EK V E + E + D+ S L E++ E+E Sbjct: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE 1282 Query: 196 RAFWMENNGHIAGEQMLE 213 R W + + H E+ LE Sbjct: 1283 RRRWQQRDRHFPEEEQLE 1300 Score = 46.2 bits (108), Expect = 2e-05 Identities = 49/205 (23%), Positives = 86/205 (41%), Gaps = 21/205 (10%) Query: 27 RSLAASSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDF--REEMWTFRGKIHAFRGQIL 84 R L A R+++ + + +EEK R + REK F EE R + + + Sbjct: 796 RQLRAEERQQREQRFLPE-EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854 Query: 85 GFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKK---YRTFWKEDKAFWKEDNA 141 G E++ +E+ +++K W++E+ + T + K KE + +E+ Sbjct: 855 GLQEDQERRRSQEQR--RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912 Query: 142 LW--ERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFW 199 L ER++ QE + + EE+ L EE LL E+ E+ E ER + Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREER-----------EKRRRQERERQYR 961 Query: 200 MENNGHIAGEQMLEDGPHNANRGQR 224 + EQ+L + P R +R Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQER 986 Score = 42.7 bits (99), Expect = 3e-04 Identities = 46/179 (25%), Positives = 82/179 (45%), Gaps = 25/179 (13%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWT--FRGK--IHAFRGQILGFWEEERP 92 RQ++ +EE+ +EE ++ RE+ E R + W +R K + Q+L E+R Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042 Query: 93 FWEEEKTFWKEE----------------KSFWEMEKSFREEEKTFWKKYRTFWKE-DKAF 135 E E+ + +EE + E+E+ +R+EE+ ++ + +E +K Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102 Query: 136 WKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEE 194 +E + L QE++ L EE+ E+R E E+ E++ EEE L EE Sbjct: 1103 RQERERQCREEEELQQEEEQLLREER----EKRRRQELERQYREEEEVQQEEEQLLREE 1157 Score = 42.7 bits (99), Expect = 3e-04 Identities = 48/195 (24%), Positives = 88/195 (45%), Gaps = 17/195 (8%) Query: 27 RSLAASSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGF 86 R +R+++L K +EE+ R+E + + + ++ ++ Q L Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766 Query: 87 WEEERPFWEEEKTFWKEEKS---FWEMEKSFREEEKTFWKK----YRTFWKEDKAFWKED 139 E +R F EEE+ + E+ E ++ FREEE+ ++ R ++ K W+E+ Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826 Query: 140 N-ALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAF 198 L E+++ L QE + E+ +E++ E E+ LW++ EE+ E ER Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE-EQELWQE-----EEQKRRQERERKL 1880 Query: 199 WMENNGHIAGEQMLE 213 E HI +Q E Sbjct: 1881 REE---HIRRQQKEE 1892 Score = 40.0 bits (92), Expect = 0.002 Identities = 48/180 (26%), Positives = 84/180 (46%), Gaps = 36/180 (20%) Query: 37 RQKKLMHKLQE-EKAFREEMKIFREKIEDF---REEMWTFRGKIHAFRGQILGFWEEERP 92 RQ++ + Q+ ++ FREE ++ +E+ E +E FR + R Q E+ER Sbjct: 1542 RQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ-----EQERK 1596 Query: 93 FWEEEKTFWKEE---KSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNL 149 F E+E+ ++E + E ++ FRE+E+ ++ E++ ++ ERDR Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER------EEQQLHRQ-----ERDRKF 1645 Query: 150 LQEDKALWEEEKALWV----------EERALLEGEK---ALWEDKTSLWEEENALWEEER 196 L+E+ L +E+ + EE+ L EGE+ E EEE L +ER Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705 Score = 39.3 bits (90), Expect = 0.003 Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 20/178 (11%) Query: 36 IRQKKLMHKLQEEKAFREEMKIFREKI------EDFREEM-WTFRG-KIHAFR-GQILGF 86 +R+++ + + E+ +REE ++ R+K ED R ++ W + K +A R ++ Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCK 1243 Query: 87 WEEERPFWEEEKTFWKEEKS-------FWEMEKSFREEEKTFWKKYRTFWKEDKAFWKED 139 E F + E + ++ +S E ++ RE+E+ W++ + E++ +E+ Sbjct: 1244 GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREE 1303 Query: 140 NALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWE-EENALWEEER 196 +R QE+K L EE+ E+R E ++ E++ L E EE L +ER Sbjct: 1304 QKEAKRRDRKSQEEKQLLREERE---EKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358 Score = 38.9 bits (89), Expect = 0.004 Identities = 44/181 (24%), Positives = 78/181 (43%), Gaps = 25/181 (13%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEE 96 +++K M Q+ + + ++ +E+ FRE+ + + Q L E +R F EE Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER----EEQQLHRQERDRKFLEE 1648 Query: 97 EKTFWKEEKSFW---EMEKSFREEEKTFWK---KYRTFWKEDKAFWKEDNAL--WERDRN 148 E ++E+ + ++ FREEE+ + + + D+ F +E+ L ER+R Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708 Query: 149 LLQEDKALWEEEKALWVEERALLEGE-------------KALWEDKTSLWEEENALWEEE 195 LQE++ L +E E L E K L E++ EE L +E Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768 Query: 196 R 196 R Sbjct: 1769 R 1769 Score = 37.0 bits (84), Expect = 0.014 Identities = 45/193 (23%), Positives = 81/193 (41%), Gaps = 11/193 (5%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFW-- 94 +Q + +L+ E+ R E ++ RE+ E+ E+ R Q L +EER W Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHE-----QERREQRLKREQEERRDWLK 459 Query: 95 -EEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQED 153 EEE ++E+ ++++ EE + W K + ++ +E E++ Q Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519 Query: 154 KALWEEEKALW-VEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQML 212 K EEE+ + L E+ ++ EEE L +E R ++ +Q+L Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579 Query: 213 EDGPHNANRGQRL 225 + R QRL Sbjct: 580 K--REEERRQQRL 590 Score = 35.8 bits (81), Expect = 0.032 Identities = 39/170 (22%), Positives = 77/170 (45%), Gaps = 13/170 (7%) Query: 38 QKKLMHKLQEEKAFREEMKIFREKIE-DFREEMWTFRGKIHAFRGQILGFWEEERPFWEE 96 Q + +L++ R + +++R++ E REE ++ + +G + +E Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213 Query: 97 E----KTFWKEEKSFWEMEKS---FREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNL 149 E + +EEK E+ F+EEE+ W+K T ++++ +E+ +R R L Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP--QRQREL 271 Query: 150 LQEDKALWEEEKALWVEERALLEGEKALWEDKTSL---WEEENALWEEER 196 +E++ L + E+ ER E ++ + L EEE +EER Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321 Score = 35.4 bits (80), Expect = 0.042 Identities = 31/139 (22%), Positives = 68/139 (48%), Gaps = 15/139 (10%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIED-FREEMWTFRGKIHAFRGQILGFWEEERPFWE 95 R+++ + + ++ FREE ++ +E+ E R + R + + + L E+E+ + Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQ---RDGKYRWEEEQLQLEEQEQRLRQ 1839 Query: 96 EEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKA 155 E ++ E+ F EKS REE++ W+E++ +++ R+ ++ ++ K Sbjct: 1840 ERDRQYRAEEQFATQEKSRREEQE--------LWQEEEQKRRQERERKLREEHIRRQQK- 1890 Query: 156 LWEEEKALWVEERALLEGE 174 EE++ V E EG+ Sbjct: 1891 --EEQRHRQVGEIKSQEGK 1907 Score = 27.7 bits (60), Expect = 8.8 Identities = 35/166 (21%), Positives = 73/166 (43%), Gaps = 14/166 (8%) Query: 46 QEEKAFREEMKIFREKIED-FREEMWTFRGKIHAFRGQILGFWEEE----RPFWEEEKTF 100 +E++ EE + RE+I+ + W + A + ++ ++ R +EEK Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR 740 Query: 101 WKEEKSFW-EMEKSFREEEKTFWKKYRTF-WKEDKAFWKEDNALW-------ERDRNLLQ 151 +E + W E E++ R++++ ++ T+ W+ ++ + L +R+R L Sbjct: 741 RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA 800 Query: 152 EDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERA 197 E++ E+ EE+ ++ E + EEE L ERA Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846 >gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapiens] Length = 693 Score = 57.4 bits (137), Expect = 1e-08 Identities = 44/208 (21%), Positives = 94/208 (45%), Gaps = 16/208 (7%) Query: 18 SRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMKIFREK------------IEDF 65 +RW S+ A + +K+ +H++QE + E+K K +E Sbjct: 241 ARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQL 300 Query: 66 REEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKY 125 ++E R ++ G++ E + K ++++ E E+ RE+E ++ Sbjct: 301 QDEAKHLRQEVEGLEGKLQSQVENNQALSLLSK---EQKQRLQEQEEMLREQEVQRVREQ 357 Query: 126 RTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLW 185 ++++ ++ L E+ L ++++ L ++E+ L EE L + EK LW+ + LW Sbjct: 358 ERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLW 417 Query: 186 EEENALWEEERAFWMENNGHIAGEQMLE 213 ++E L ++E + N H +Q+ E Sbjct: 418 KKEERLQKQEERLALSQN-HKLDKQLAE 444 >gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sapiens] Length = 693 Score = 57.0 bits (136), Expect = 1e-08 Identities = 43/208 (20%), Positives = 93/208 (44%), Gaps = 16/208 (7%) Query: 18 SRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMK------------IFREKIEDF 65 +RW S+ A + +K+ +H++QE + E+K +E Sbjct: 241 ARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQL 300 Query: 66 REEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKY 125 ++E R ++ G++ E + K ++++ E E+ RE+E ++ Sbjct: 301 QDEAKHLRQEVEGLEGKLQSQVENNQALSLLSK---EQKQRLQEQEEMLREQEAQRVREQ 357 Query: 126 RTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLW 185 ++++ ++ L E+ L ++++ L ++E+ L EE L + EK LW+ + LW Sbjct: 358 ERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLW 417 Query: 186 EEENALWEEERAFWMENNGHIAGEQMLE 213 ++E L ++E + N H +Q+ E Sbjct: 418 KKEERLQKQEERLALSQN-HKLDKQLAE 444 >gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C isoform 1 [Homo sapiens] Length = 693 Score = 57.0 bits (136), Expect = 1e-08 Identities = 43/208 (20%), Positives = 93/208 (44%), Gaps = 16/208 (7%) Query: 18 SRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMK------------IFREKIEDF 65 +RW S+ A + +K+ +H++QE + E+K +E Sbjct: 241 ARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQL 300 Query: 66 REEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKY 125 ++E R ++ G++ E + K ++++ E E+ RE+E ++ Sbjct: 301 QDEAKHLRQEVEGLEGKLQSQVENNQALSLLSK---EQKQRLQEQEEMLREQEAQRVREQ 357 Query: 126 RTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLW 185 ++++ ++ L E+ L ++++ L ++E+ L EE L + EK LW+ + LW Sbjct: 358 ERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLW 417 Query: 186 EEENALWEEERAFWMENNGHIAGEQMLE 213 ++E L ++E + N H +Q+ E Sbjct: 418 KKEERLQKQEERLALSQN-HKLDKQLAE 444 >gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapiens] Length = 693 Score = 57.0 bits (136), Expect = 1e-08 Identities = 43/208 (20%), Positives = 93/208 (44%), Gaps = 16/208 (7%) Query: 18 SRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMK------------IFREKIEDF 65 +RW S+ A + +K+ +H++QE + E+K +E Sbjct: 241 ARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQL 300 Query: 66 REEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKY 125 ++E R ++ G++ E + K ++++ E E+ RE+E ++ Sbjct: 301 QDEAKHLRQEVEGLEGKLQSQVENNQALSLLSK---EQKQRLQEQEEMLREQEAQRVREQ 357 Query: 126 RTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLW 185 ++++ ++ L E+ L ++++ L ++E+ L EE L + EK LW+ + LW Sbjct: 358 ERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLW 417 Query: 186 EEENALWEEERAFWMENNGHIAGEQMLE 213 ++E L ++E + N H +Q+ E Sbjct: 418 KKEERLQKQEERLALSQN-HKLDKQLAE 444 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 52.4 bits (124), Expect = 3e-07 Identities = 55/199 (27%), Positives = 81/199 (40%), Gaps = 44/199 (22%) Query: 33 SPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERP 92 SP +K + + + K RE K R+ E+ EEM T K+ G+++ E P Sbjct: 1399 SPKQGRKAVQKERKVGKIKREMTKEERDMSEEV-EEMATLEEKVVKQEGKLVMI--ERTP 1455 Query: 93 FWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQE 152 W++ K W E W K E + WK WKE+ WE+ LLQE Sbjct: 1456 SWQDWKKAWDE----W---KQVHGETRKSWKA-----------WKEE---WEK--RLLQE 1492 Query: 153 DKALWEEEKALWVEERALLEGEKALWEDKTSLWE--------------EENALWEEERAF 198 ++ L + + L EE L E +K WE+ +WE EE EEE Sbjct: 1493 EEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEE--- 1549 Query: 199 WMENNGHIAGEQMLEDGPH 217 + G +Q+ E+ H Sbjct: 1550 -VSREGEEKEQQVTEEQRH 1567 Score = 47.0 bits (110), Expect = 1e-05 Identities = 48/189 (25%), Positives = 88/189 (46%), Gaps = 18/189 (9%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEE 96 R +KL + ++ R+++ EK+ E++ GK+ + IL EE P Sbjct: 1647 RGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKN-ILAQKVEELP---- 1701 Query: 97 EKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKAL 156 +E+ W+ ++ +E E+ W WKE++ +E+ L E + L +E++AL Sbjct: 1702 ----QREQNLDWQEKELAQELEELEWDMEELSWKEEELN-QEEGKLVEEKKKLAEEEEAL 1756 Query: 157 -WEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLEDG 215 W+ EK L EE L + E+ L ++K L + + + EEE + EQ++E Sbjct: 1757 AWQREK-LSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR------EQLIEKK 1809 Query: 216 PHNANRGQR 224 A + +R Sbjct: 1810 MKLAQKRER 1818 Score = 45.4 bits (106), Expect = 4e-05 Identities = 56/218 (25%), Positives = 99/218 (45%), Gaps = 32/218 (14%) Query: 37 RQKKLMHKLQEEKAFREEMKIF-REKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWE 95 ++KK + + +E+ A R+E ++ +E++ ++++ + K+ F +IL EE+ + Sbjct: 1841 QEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFN-KILAQVEEK--LTQ 1897 Query: 96 EEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR-----NLL 150 E++T K+++ E EK + E + KK +E E + + R ++ Sbjct: 1898 EKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIA 1957 Query: 151 QEDKALWEEEKALWVEERALLEG---------------------EKALWEDKTSLWEEEN 189 +E+KAL E K L E+ L+EG E+ L+E K SL EE Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSL--EEK 2015 Query: 190 ALWEEERAFWMENNGHIAGEQMLEDGPHNANRGQRLLA 227 L E+R ME + G+ G +GQR LA Sbjct: 2016 ILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLA 2053 Score = 41.2 bits (95), Expect = 8e-04 Identities = 49/214 (22%), Positives = 94/214 (43%), Gaps = 19/214 (8%) Query: 29 LAASSPSIRQKKLMHKLQEEKAFREEMK-------------IFREKIEDF--REEMWTFR 73 L+ + + QK+ + EK REE K I +K+E+ RE+ ++ Sbjct: 1651 LSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQ 1710 Query: 74 GKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTF-WKKYRTFWKED 132 K A + L W+ E W+EE+ +EE E +K EEE+ W++ + +E Sbjct: 1711 EKELAQELEELE-WDMEELSWKEEELN-QEEGKLVEEKKKLAEEEEALAWQREKLSEEET 1768 Query: 133 KAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALW 192 K +E+ + E+++ L Q + + EEE+ L + L+E + L + + L Sbjct: 1769 KLAQEEELLIQEKEK-LAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELT 1827 Query: 193 EEERAFWMENNGHIAGEQMLEDGPHNANRGQRLL 226 + + + + N + + ++ A R + LL Sbjct: 1828 KNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLL 1861 Score = 40.8 bits (94), Expect = 0.001 Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 25/174 (14%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 +E K +EE K+ +E+ + +EE + + + + E F ++E+T + + Sbjct: 1591 EERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDD-REMAQAEGKFAQKEETLAQRGE 1649 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWE--------------RDRNLLQ 151 + + ++ K KK+ +E++ K+ L E R++NL Sbjct: 1650 KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709 Query: 152 EDKAL--------WEEEKALWVEERALLEGEKALWEDKTSLWEEENAL-WEEER 196 ++K L W+ E+ W EE L + E L E+K L EEE AL W+ E+ Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEE-LNQEEGKLVEEKKKLAEEEEALAWQREK 1762 Score = 38.9 bits (89), Expect = 0.004 Identities = 44/155 (28%), Positives = 72/155 (46%), Gaps = 13/155 (8%) Query: 46 QEEKAFREEMKIFREKIEDFREE---MWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWK 102 +EE+ +EE K+ EK + EE W R K+ ++ EEE E+EK Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQ-REKLSEEETKLAQ--EEELLIQEKEKLAQH 1787 Query: 103 EEKSFWEMEKSFREEEKTFWKKYRTFWKEDK------AFWKEDNALWERDRNLLQEDKAL 156 +EK E E+ R+ E+ KK + K ++ K L+++ +NL QE K L Sbjct: 1788 KEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQK-KNLAQEKKNL 1846 Query: 157 WEEEKALWVEERALLEGEKALWEDKTSLWEEENAL 191 +E++ L + LL ++ L K L + +N L Sbjct: 1847 AQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKL 1881 Score = 36.2 bits (82), Expect = 0.025 Identities = 41/168 (24%), Positives = 77/168 (45%), Gaps = 12/168 (7%) Query: 37 RQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEE 96 R++ L + +E EE++ E++ EE+ GK+ + ++ EEE W+ Sbjct: 1703 REQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAE--EEEALAWQR 1760 Query: 97 EKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKAL 156 EK +E K E E +E+EK K + +E++ K + + E+ L Q+ + Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLI-EKKMKLAQK-RER 1818 Query: 157 WEEEKALWVEERALLEGEKALWEDKTSLWEE--------ENALWEEER 196 W + + +L +K L ++K +L +E EN L+ +ER Sbjct: 1819 WINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKER 1866 Score = 35.0 bits (79), Expect = 0.055 Identities = 45/203 (22%), Positives = 78/203 (38%), Gaps = 36/203 (17%) Query: 35 SIRQKKLMHKLQEEKAFREEM-KIFREKIEDFREEMWTFR-----GKIHAFRGQI-LGFW 87 S + K+ +K +EE EE+ + EK + EE + +IH R + Sbjct: 1530 SSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRA 1589 Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 +EER +EE+ +EE+ + E+ + + R + + F +++ L +R Sbjct: 1590 QEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGE 1649 Query: 148 NLLQEDKALWEEEKAL---W-----VEERALLEGEKAL---------------------W 178 L QE + L ++ K L W EE+ +G K W Sbjct: 1650 KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709 Query: 179 EDKTSLWEEENALWEEERAFWME 201 ++K E E W+ E W E Sbjct: 1710 QEKELAQELEELEWDMEELSWKE 1732 Score = 31.6 bits (70), Expect = 0.61 Identities = 46/201 (22%), Positives = 83/201 (41%), Gaps = 35/201 (17%) Query: 34 PSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPF 93 P + + +++ E+ F EEM+ +++E ++E + + + EEE Sbjct: 2209 PKEKFSSQVDEVESEEHFSEEMESLLDELE--KQESLSSEEEEEREEEEER---EEEEVR 2263 Query: 94 WEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQED 153 EEE+ KEE+ E + EEEK KK E+ + +QE Sbjct: 2264 EEEEER--KEEEEGEEKQVEKEEEEKKKKKK-------------------EKKKEEVQEK 2302 Query: 154 KALWEEEKALWVEERALLEGEKALWEDKTSLWEE---ENALWEEERAFWMEN------NG 204 + ++EE++ + EE ++ E+ SL EE E + ++E+ F ++ G Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRG 2362 Query: 205 HIAGEQMLEDGPHNANRGQRL 225 +L PH R RL Sbjct: 2363 RERVLSILRGVPHGKGRAIRL 2383 Score = 30.8 bits (68), Expect = 1.0 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 29/170 (17%) Query: 37 RQKKLMH---KLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPF 93 RQ+K+ +L E K EE + E EE +GK+ RGQ R F Sbjct: 1994 RQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQ--------RIF 2045 Query: 94 WEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQED 153 + ++ K + + +S +E K + K L +R L QE+ Sbjct: 2046 VQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQK-----------LTRDERKLTQEE 2094 Query: 154 KALWEEEKALWVEERALLEGEKAL----W---EDKTSLWEEENALWEEER 196 + + ++AL+V+ER L + L W E ++ L ++E L ++R Sbjct: 2095 IKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQR 2144 Score = 30.0 bits (66), Expect = 1.8 Identities = 35/171 (20%), Positives = 67/171 (39%), Gaps = 6/171 (3%) Query: 27 RSLAASSPSIRQKKLMHKLQEEKAFREEMKIFR--EKIEDFREEMWTFRGKIHAFRGQIL 84 R LA I + KL + + + K+ + K+ RE + K++ + Sbjct: 2022 RILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQ 2081 Query: 85 GFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWE 144 +ER +EE K +++ + E+ E+ K F ++ K++ L Sbjct: 2082 KLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLAR 2141 Query: 145 RDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 + R L + + + +E+ + EE L + D EEE + EEE Sbjct: 2142 KQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDD----EEEGGIEEEE 2188 >gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 479 Score = 47.0 bits (110), Expect = 1e-05 Identities = 30/109 (27%), Positives = 60/109 (55%), Gaps = 3/109 (2%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 E+E E+E+ ++E+ E E+ E+E+ ++ ++++ +++ L E++ Sbjct: 203 EQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEE 262 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 L ++++ L E+EK L +ER L E EK L +++ EE+ L E ER Sbjct: 263 RLCEQEERLCEQEK-LPGQERLLEEVEKLLEQERRQ--EEQERLLERER 308 Score = 46.2 bits (108), Expect = 2e-05 Identities = 26/108 (24%), Positives = 59/108 (54%), Gaps = 2/108 (1%) Query: 89 EERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRN 148 +E E+E+ ++E+ E E+ E+E+ ++ ++++ +++ L E++ Sbjct: 197 QEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEER 256 Query: 149 LLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 L ++++ L E+E+ L +E+ L G++ L E+ L E+E E+ER Sbjct: 257 LCEQEERLCEQEERLCEQEK--LPGQERLLEEVEKLLEQERRQEEQER 302 Score = 40.8 bits (94), Expect = 0.001 Identities = 25/82 (30%), Positives = 48/82 (58%), Gaps = 1/82 (1%) Query: 115 REEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGE 174 R+EE+ ++ R +E++ +E+ L E++ L ++++ L E+E+ L +E L E E Sbjct: 196 RQEERLREQEERLHEQEERLHEQEER-LCEQEERLCEQEERLREQEERLREQEERLHEQE 254 Query: 175 KALWEDKTSLWEEENALWEEER 196 + L E + L E+E L E+E+ Sbjct: 255 ERLCEQEERLCEQEERLCEQEK 276 Score = 36.6 bits (83), Expect = 0.019 Identities = 46/178 (25%), Positives = 80/178 (44%), Gaps = 18/178 (10%) Query: 38 QKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEE 97 Q++ +H+ QEE+ +E ++ ++ E E+ R + R Q E+E E+E Sbjct: 204 QEERLHE-QEERLHEQEERLCEQE-ERLCEQEERLREQEERLREQEERLHEQEERLCEQE 261 Query: 98 KTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALW 157 + ++E+ E EK +E R + +K E E LL+ ++ L Sbjct: 262 ERLCEQEERLCEQEKLPGQE--------RLLEEVEKLL--EQERRQEEQERLLERERLLD 311 Query: 158 EEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLEDG 215 E E+ L E+ L + ++ LW+ +T E L E ER +E + E+MLE G Sbjct: 312 EVEELL--EQERLRQQDERLWQQET--LRELERLRELERLRELERLREL--ERMLELG 363 Score = 31.6 bits (70), Expect = 0.61 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 1/76 (1%) Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENAL-WEEERAFWMENNGHIAGE 209 ++++ L E+E+ L +E L E E+ L E + L E+E L +EER E H E Sbjct: 196 RQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEE 255 Query: 210 QMLEDGPHNANRGQRL 225 ++ E + +RL Sbjct: 256 RLCEQEERLCEQEERL 271 >gi|95147555 microtubule-associated protein 1A [Homo sapiens] Length = 2803 Score = 44.3 bits (103), Expect = 9e-05 Identities = 25/108 (23%), Positives = 60/108 (55%) Query: 89 EERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRN 148 ++ +++++ + ++ + +K+ ++ + +K ++DKA +D L E+D+ Sbjct: 1383 KDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKA 1442 Query: 149 LLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 L Q+DK E++KAL ++ AL + +KAL L +++ L ++E+ Sbjct: 1443 LEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEK 1490 Score = 43.1 bits (100), Expect = 2e-04 Identities = 30/133 (22%), Positives = 66/133 (49%) Query: 45 LQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEE 104 LQ++ E ++ K ++ K A + Q ++ R +++ +++ Sbjct: 1367 LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKD 1426 Query: 105 KSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALW 164 K+ +K E++K +K + ++DKA ++D AL ++D+ L +DK L ++++ L Sbjct: 1427 KALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE 1486 Query: 165 VEERALLEGEKAL 177 +E+ E +KAL Sbjct: 1487 QKEKIPEEKDKAL 1499 Score = 41.2 bits (95), Expect = 8e-04 Identities = 31/120 (25%), Positives = 64/120 (53%), Gaps = 12/120 (10%) Query: 87 WEEERPFWEEEKTFWKEEKS-----FWEMEKSFREEE------KTFWKKYRTFWKEDKAF 135 WE++ P ++ + K+E + +K+ +E ++K +++A Sbjct: 1342 WEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAV 1401 Query: 136 WKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEE 195 ++D AL ++ R+L Q+D AL +++KAL +++ L E +KAL E K + EE++ E++ Sbjct: 1402 KQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKAL-EQKDKIPEEKDKALEQK 1460 Score = 41.2 bits (95), Expect = 8e-04 Identities = 23/103 (22%), Positives = 59/103 (57%) Query: 95 EEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDK 154 +++K ++ + + + + +++K K + ++DKA ++D E+D+ L Q+D Sbjct: 1403 QQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDT 1462 Query: 155 ALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERA 197 AL +++KAL +++ L + ++ L + + E++ AL ++ R+ Sbjct: 1463 ALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRS 1505 Score = 38.5 bits (88), Expect = 0.005 Identities = 21/102 (20%), Positives = 59/102 (57%) Query: 95 EEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDK 154 E ++ ++ + ++ +++ + + ++ + ++ + ++D AL ++D+ L +DK Sbjct: 1375 EHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDK 1434 Query: 155 ALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 L E++KAL +++ E +KAL + T+L +++ AL +++ Sbjct: 1435 DLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDK 1476 Score = 37.4 bits (85), Expect = 0.011 Identities = 22/82 (26%), Positives = 48/82 (58%) Query: 116 EEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEK 175 ++++ K ++DKA ++ L ++D L Q+DKAL ++K L +++AL + +K Sbjct: 1389 QKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDK 1448 Query: 176 ALWEDKTSLWEEENALWEEERA 197 E +L +++ AL ++++A Sbjct: 1449 IPEEKDKALEQKDTALEQKDKA 1470 Score = 36.2 bits (82), Expect = 0.025 Identities = 39/165 (23%), Positives = 80/165 (48%), Gaps = 7/165 (4%) Query: 46 QEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEK 105 Q++KA + K EK + ++ K A + ++++ ++K ++++ Sbjct: 1424 QKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDR 1483 Query: 106 SFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWV 165 + EK E++K +K R+ E KA ED +DR+L Q DKA ++ +A Sbjct: 1484 VLEQKEKIPEEKDKALDQKVRSV--EHKA--PEDTVAEMKDRDLEQTDKAPEQKHQAQEQ 1539 Query: 166 EERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQ 210 +++ + ++AL + +L +++ AL + +A +E N H EQ Sbjct: 1540 KDKVSEKKDQALEQKYWALGQKDEALEQNIQA--LEEN-HQTQEQ 1581 Score = 32.7 bits (73), Expect = 0.27 Identities = 31/125 (24%), Positives = 64/125 (51%), Gaps = 16/125 (12%) Query: 89 EERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWK-----EDNALW 143 ++R + +K ++ ++ + +K ++++ +KY ++D+A + E+N Sbjct: 1519 KDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQT 1578 Query: 144 ERDRNLLQEDKA----LWEE---EKALWVEER--ALLEGEKALWEDKTSLWEEENALWEE 194 + +L+QEDK + EE EK +EE+ ALLE KAL +++ + +E E+ Sbjct: 1579 QEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLV--QEGRAREQ 1636 Query: 195 ERAFW 199 E +W Sbjct: 1637 EEKYW 1641 Score = 32.0 bits (71), Expect = 0.47 Identities = 24/123 (19%), Positives = 59/123 (47%), Gaps = 9/123 (7%) Query: 47 EEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKS 106 + +A +++ K +K D ++ K A +++ E++K +++K Sbjct: 1397 KNEAVKQQDKALEQKGRDLEQKDTALEQKDKALE-------PKDKDLEEKDKALEQKDKI 1449 Query: 107 FWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVE 166 E +K+ +++ +K + +DK ++D L ++++ ++DKAL ++K VE Sbjct: 1450 PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKAL--DQKVRSVE 1507 Query: 167 ERA 169 +A Sbjct: 1508 HKA 1510 Score = 28.5 bits (62), Expect = 5.2 Identities = 20/94 (21%), Positives = 44/94 (46%), Gaps = 9/94 (9%) Query: 38 QKKLMHKLQEEKAFREEMKIFRE-KIEDFREEMWTFRGKIHAF------RGQILGFWEEE 90 ++KL L++ KA E + +E + + E+ W + + + R + G +E Sbjct: 1608 EEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKEL 1667 Query: 91 RPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKK 124 P WE+ T +++ +W + E+ T+W++ Sbjct: 1668 APAWED--TSPEQDNRYWRGREDVALEQDTYWRE 1699 >gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 isoform a [Homo sapiens] Length = 445 Score = 41.2 bits (95), Expect = 8e-04 Identities = 30/130 (23%), Positives = 64/130 (49%), Gaps = 8/130 (6%) Query: 50 AFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWE 109 A + E +EK+E+ +E + ++ I EE+ W ++K WK+++ F E Sbjct: 195 ALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEK---WSKQKAKWKKDEKF-E 250 Query: 110 MEKSFREEEKTFWKKYR-TFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEER 168 E +++K KK+ +EDK + +A++E N +QE + L ++ ++ ++ Sbjct: 251 RENILLQQKKKMTKKFEMESGEEDKKINESCSAVFE---NFIQEKEELLKQHQSDTLQLE 307 Query: 169 ALLEGEKALW 178 L + ++ W Sbjct: 308 ELRKTKEVPW 317 Score = 33.5 bits (75), Expect = 0.16 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Query: 105 KSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEE-EKAL 163 K + ++ FR + + + + W + KA WK+D +ER+ LLQ+ K + ++ E Sbjct: 212 KEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEK-FERENILLQQKKKMTKKFEMES 270 Query: 164 WVEERALLEGEKALWED 180 E++ + E A++E+ Sbjct: 271 GEEDKKINESCSAVFEN 287 Score = 28.9 bits (63), Expect = 3.9 Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 2/87 (2%) Query: 109 EMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEER 168 EM K ++ + F + + E + W + A W++D +E+ L +++K E Sbjct: 209 EMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEM 268 Query: 169 ALLEGEKALWEDKTSLWEEENALWEEE 195 E +K + E ++++ EN + E+E Sbjct: 269 ESGEEDKKINESCSAVF--ENFIQEKE 293 >gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 isoform b [Homo sapiens] Length = 422 Score = 40.8 bits (94), Expect = 0.001 Identities = 30/132 (22%), Positives = 66/132 (50%), Gaps = 8/132 (6%) Query: 50 AFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWE 109 A + E +EK+E+ +E + ++ I EE+ W ++K WK+++ F E Sbjct: 195 ALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEK---WSKQKAKWKKDEKF-E 250 Query: 110 MEKSFREEEKTFWKKYR-TFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEER 168 E +++K KK+ +EDK + +A++E N +QE + L ++ ++ ++ Sbjct: 251 RENILLQQKKKMTKKFEMESGEEDKKINESCSAVFE---NFIQEKEELLKQHQSDTLQLE 307 Query: 169 ALLEGEKALWED 180 L + ++ + E+ Sbjct: 308 ELRKTKEVMQEE 319 Score = 28.9 bits (63), Expect = 3.9 Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 2/87 (2%) Query: 109 EMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEER 168 EM K ++ + F + + E + W + A W++D +E+ L +++K E Sbjct: 209 EMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEM 268 Query: 169 ALLEGEKALWEDKTSLWEEENALWEEE 195 E +K + E ++++ EN + E+E Sbjct: 269 ESGEEDKKINESCSAVF--ENFIQEKE 293 >gi|56676397 ankyrin repeat domain 11 [Homo sapiens] Length = 2663 Score = 40.0 bits (92), Expect = 0.002 Identities = 34/154 (22%), Positives = 76/154 (49%), Gaps = 13/154 (8%) Query: 45 LQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEE 104 L+ + + ++K+ + + F++E + K+ EE+ +++EK+ + + Sbjct: 674 LENDLSTENKLKVLKHDRDHFKKEEKLSKMKL-----------EEKEWLFKDEKSLKRIK 722 Query: 105 KSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALW 164 + ++ +SFREE+ K + ++K+ +E L++ +R +D+ E+K Sbjct: 723 DTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDL 782 Query: 165 VEERALLEGEKALWEDKTSLWEEENALWEEERAF 198 E++ E EK EDK L +E+ ++ E+ AF Sbjct: 783 KEDKISKEKEKIFKEDKEKLKKEK--VYREDSAF 814 >gi|169208458 PREDICTED: similar to golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 432 Score = 39.3 bits (90), Expect = 0.003 Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 14/128 (10%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 E+E E+E+ ++E+ E E+ RE+E+ E + ++ L E ++ Sbjct: 203 EQEERLREQEERLCEQEERLCEQEERLREQEERLC--------EQEKLPGQERLLEEVEK 254 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIA 207 L QE + EE++ L ER L E E+ L +++ L +++ LW++E +E + Sbjct: 255 LLKQERRQ--EEQERLLERERLLDEVEELLEQER--LRQQDERLWQQETLRELERLREL- 309 Query: 208 GEQMLEDG 215 E+MLE G Sbjct: 310 -ERMLELG 316 Score = 30.8 bits (68), Expect = 1.0 Identities = 16/46 (34%), Positives = 28/46 (60%) Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 ++++ L E+E+ L +E L E E+ L E + L E+E L E+E+ Sbjct: 196 RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEK 241 Score = 28.1 bits (61), Expect = 6.7 Identities = 15/50 (30%), Positives = 28/50 (56%) Query: 145 RDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEE 194 ++ L ++++ L E+E+ L +E L E E+ L E + L E+E +E Sbjct: 197 QEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQE 246 >gi|154937324 hypothetical protein LOC440295 [Homo sapiens] Length = 432 Score = 39.3 bits (90), Expect = 0.003 Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 14/128 (10%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 E+E E+E+ ++E+ E E+ RE+E+ E + ++ L E ++ Sbjct: 203 EQEERLREQEERLCEQEERLCEQEERLREQEERLC--------EQEKLPGQERLLEEVEK 254 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIA 207 L QE + EE++ L ER L E E+ L +++ L +++ LW++E +E + Sbjct: 255 LLKQERRQ--EEQERLLERERLLDEVEELLEQER--LRQQDERLWQQETLRELERLREL- 309 Query: 208 GEQMLEDG 215 E+MLE G Sbjct: 310 -ERMLELG 316 Score = 30.8 bits (68), Expect = 1.0 Identities = 16/46 (34%), Positives = 28/46 (60%) Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 ++++ L E+E+ L +E L E E+ L E + L E+E L E+E+ Sbjct: 196 RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEK 241 Score = 28.1 bits (61), Expect = 6.7 Identities = 15/50 (30%), Positives = 28/50 (56%) Query: 145 RDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEE 194 ++ L ++++ L E+E+ L +E L E E+ L E + L E+E +E Sbjct: 197 QEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQE 246 >gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sapiens] Length = 432 Score = 38.5 bits (88), Expect = 0.005 Identities = 33/127 (25%), Positives = 66/127 (51%), Gaps = 7/127 (5%) Query: 89 EERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRN 148 +E E+E+ ++E+ E E+ E+E+ ++ +++K +E L E Sbjct: 197 QEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQE--RLLEEVEK 254 Query: 149 LLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAG 208 LL++++ EE++ L ER L E E+ L +++ L +++ LW++E +E + Sbjct: 255 LLEQERR-QEEQERLLERERLLDEVEELLEQER--LRQQDERLWQQETLRELERLREL-- 309 Query: 209 EQMLEDG 215 E+MLE G Sbjct: 310 ERMLELG 316 Score = 30.4 bits (67), Expect = 1.4 Identities = 16/46 (34%), Positives = 28/46 (60%) Query: 151 QEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEER 196 ++++ L E+E+ L +E L E E+ L E + L E+E L E+E+ Sbjct: 196 RQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEK 241 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 38.5 bits (88), Expect = 0.005 Identities = 38/124 (30%), Positives = 63/124 (50%), Gaps = 7/124 (5%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 +E+ E EK ++ K MEK T K+ + ++DKA +AL E+ + Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEK-IPPMVTTDQKQEESKLEKDKA-----SALQEK-K 1212 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIA 207 L +E K + EEEK E++ LLE +K EDK L E + + EE++ +++ IA Sbjct: 1213 PLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIA 1272 Query: 208 GEQM 211 E++ Sbjct: 1273 EEKL 1276 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 38.5 bits (88), Expect = 0.005 Identities = 38/124 (30%), Positives = 63/124 (50%), Gaps = 7/124 (5%) Query: 88 EEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDR 147 +E+ E EK ++ K MEK T K+ + ++DKA +AL E+ + Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEK-IPPMVTTDQKQEESKLEKDKA-----SALQEK-K 1212 Query: 148 NLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIA 207 L +E K + EEEK E++ LLE +K EDK L E + + EE++ +++ IA Sbjct: 1213 PLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIA 1272 Query: 208 GEQM 211 E++ Sbjct: 1273 EEKL 1276 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.133 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,578,162 Number of Sequences: 37866 Number of extensions: 551885 Number of successful extensions: 4696 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 56 Number of HSP's successfully gapped in prelim test: 141 Number of HSP's that attempted gapping in prelim test: 2275 Number of HSP's gapped (non-prelim): 746 length of query: 233 length of database: 18,247,518 effective HSP length: 99 effective length of query: 134 effective length of database: 14,498,784 effective search space: 1942837056 effective search space used: 1942837056 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.