BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|157412263 cyclin M1 [Homo sapiens] (951 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|157412263 cyclin M1 [Homo sapiens] 1909 0.0 gi|40068053 cyclin M2 isoform 1 [Homo sapiens] 731 0.0 gi|40068055 cyclin M2 isoform 2 [Homo sapiens] 727 0.0 gi|94681046 cyclin M4 [Homo sapiens] 640 0.0 gi|40068049 cyclin M3 isoform 1 [Homo sapiens] 513 e-145 gi|40068047 cyclin M3 isoform 2 [Homo sapiens] 416 e-116 gi|40068051 cyclin M2 isoform 3 [Homo sapiens] 365 e-100 gi|92859678 small nuclear RNA activating complex, polypeptide 4,... 37 0.088 gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 37 0.11 gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 37 0.11 gi|39812378 RAN binding protein 9 [Homo sapiens] 36 0.15 gi|239746493 PREDICTED: hypothetical protein XP_002343745 [Homo ... 35 0.25 gi|222352127 sidekick 2 [Homo sapiens] 35 0.33 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 35 0.33 gi|133922582 zinc finger protein 358 [Homo sapiens] 35 0.33 gi|62241036 hypothetical protein LOC541565 [Homo sapiens] 35 0.43 gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 34 0.57 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 34 0.57 gi|115511036 alpha-kinase 3 [Homo sapiens] 34 0.57 gi|118200352 hypothetical protein LOC642273 [Homo sapiens] 34 0.74 gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 34 0.74 gi|27734911 DAZ interacting protein 1-like [Homo sapiens] 34 0.74 gi|55741677 SET domain containing 1A [Homo sapiens] 33 0.97 gi|50511941 EMI domain containing 1 [Homo sapiens] 33 0.97 gi|163965366 nascent polypeptide-associated complex alpha subuni... 33 0.97 gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 33 0.97 gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 33 0.97 gi|239757128 PREDICTED: similar to mCG141871 [Homo sapiens] 33 1.3 gi|113428456 PREDICTED: similar to mCG141871 [Homo sapiens] 33 1.3 gi|113428072 PREDICTED: similar to mCG141871 [Homo sapiens] 33 1.3 >gi|157412263 cyclin M1 [Homo sapiens] Length = 951 Score = 1909 bits (4944), Expect = 0.0 Identities = 951/951 (100%), Positives = 951/951 (100%) Query: 1 MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGG 60 MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGG Sbjct: 1 MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGG 60 Query: 61 TLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAP 120 TLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAP Sbjct: 61 TLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAP 120 Query: 121 SAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGG 180 SAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGG Sbjct: 121 SAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGG 180 Query: 181 GKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFS 240 GKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFS Sbjct: 181 GKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFS 240 Query: 241 GLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGW 300 GLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGW Sbjct: 241 GLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGW 300 Query: 301 LYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVC 360 LYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVC Sbjct: 301 LYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVC 360 Query: 361 LTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQG 420 LTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQG Sbjct: 361 LTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQG 420 Query: 421 ALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILF 480 ALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILF Sbjct: 421 ALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILF 480 Query: 481 VKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGE 540 VKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGE Sbjct: 481 VKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGE 540 Query: 541 GDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTE 600 GDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTE Sbjct: 541 GDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTE 600 Query: 601 MRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHY 660 MRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHY Sbjct: 601 MRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHY 660 Query: 661 LYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLA 720 LYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLA Sbjct: 661 LYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLA 720 Query: 721 GSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVK 780 GSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVK Sbjct: 721 GSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVK 780 Query: 781 ITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRNSL 840 ITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRNSL Sbjct: 781 ITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRNSL 840 Query: 841 PCSRSDGLRSPSEVVYLRMEELAFTQEEMTDFEEHSTQQLTLSPAAVPTRAASDSECCNI 900 PCSRSDGLRSPSEVVYLRMEELAFTQEEMTDFEEHSTQQLTLSPAAVPTRAASDSECCNI Sbjct: 841 PCSRSDGLRSPSEVVYLRMEELAFTQEEMTDFEEHSTQQLTLSPAAVPTRAASDSECCNI 900 Query: 901 NLDTETSPCSSDFEENVGKKLLRTLSGQKRKRSPEGERTSEDNSNLTPLIT 951 NLDTETSPCSSDFEENVGKKLLRTLSGQKRKRSPEGERTSEDNSNLTPLIT Sbjct: 901 NLDTETSPCSSDFEENVGKKLLRTLSGQKRKRSPEGERTSEDNSNLTPLIT 951 >gi|40068053 cyclin M2 isoform 1 [Homo sapiens] Length = 875 Score = 731 bits (1888), Expect = 0.0 Identities = 433/848 (51%), Positives = 540/848 (63%), Gaps = 98/848 (11%) Query: 42 LLGLRPEDTAGGRVS-LEGGTLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTG 100 ++GLR EDT VS +EGG LR +E T LRVY G+N Sbjct: 74 IIGLRLEDT--NDVSFMEGGALRVSERTRVKLRVY-------------------GQNINN 112 Query: 101 DWAPRLVFIEEP-----PGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVA 155 + R+ F E PG G+ A P GPQRC ++ SD+ +L P Sbjct: 113 ETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRT---SDIIIL-PHIILNRR 168 Query: 156 GSALVQVRVRELRKGEAERG------------GAGG--------GGKLFSLCA------W 189 S ++++ ++ LRK E + GAGG GGK S A W Sbjct: 169 TSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPW 228 Query: 190 DGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSL 249 W +H ++ G L P WL+ + LLL LS +FSGL L L++L Sbjct: 229 AETTWIYHDGEDTKMI------VGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMAL 282 Query: 250 DPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYTSLPPGF 309 DP+ELR+++N G+ E+ A+R++ VR +G +LLC+LLLG N L T L Sbjct: 283 DPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTL-----TILLDDI 337 Query: 310 GGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAA 369 G+G + +V T + + EI P ++CSRHGLA+ ++++ LT+ M Sbjct: 338 AGSG-----------LVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMT 386 Query: 370 FPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVV 429 FP YP+ +LLD L QEI T Y REKLLE LR DPY+DLVKEELNIIQGALELRTK V Sbjct: 387 FPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTV 446 Query: 430 EEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDP 489 E+V+TPL DCFM+ +A+LDF T+SEI+ SGYTRIPV+EG+ R NIVD+LFVKDLAFVDP Sbjct: 447 EDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGE-RSNIVDLLFVKDLAFVDP 505 Query: 490 DDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMG 549 DDCTPL T+T+FYN PLH VFNDT+LD +LEEFKKGKSHLAIVQRVNNEGEGDPFYEV+G Sbjct: 506 DDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLG 565 Query: 550 IVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQL 609 IVTLED+IEEIIKSEILDETDLYTDNR K++V RERK+ DFS FK +D+EM+VKISPQL Sbjct: 566 IVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQ-DFSAFKQTDSEMKVKISPQL 624 Query: 610 LLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVD 669 LLA HRF+ATEVE F +SEKILLRLLKHPNVIQELK+DEKNKKAPE+YLYQRN+PVD Sbjct: 625 LLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVD 684 Query: 670 YFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACSDN-----DVRKVGSLAGSSV 724 YFVL+LQGKVEVE GKEG++FE AF+YYGV A+ + + V + LA S Sbjct: 685 YFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTELLAAGSP 744 Query: 725 FLNRSPSRCSGLNRSESPNR-ERSD-----FGGSNTQLYSSSNNLYMPDYSVHILSDVQF 778 N+SP R GLN S+S +R +R D G SN QL SS +Y+PDYSV LSD+QF Sbjct: 745 GENKSPPRPCGLNHSDSLSRSDRIDAVTPTLGSSNNQLNSSLLQVYIPDYSVRALSDLQF 804 Query: 779 VKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRN 838 VKI+RQQYQNAL A MD +PQS +D ++TK T D LLN +N Sbjct: 805 VKISRQQYQNALMASRMDKTPQS------SDSENTKIELTLTELHDGLPDETANLLNEQN 858 Query: 839 SLPCSRSD 846 + S+++ Sbjct: 859 CVTHSKAN 866 >gi|40068055 cyclin M2 isoform 2 [Homo sapiens] Length = 853 Score = 727 bits (1876), Expect = 0.0 Identities = 430/843 (51%), Positives = 535/843 (63%), Gaps = 110/843 (13%) Query: 42 LLGLRPEDTAGGRVS-LEGGTLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTG 100 ++GLR EDT VS +EGG LR +E T LRVY G+N Sbjct: 74 IIGLRLEDT--NDVSFMEGGALRVSERTRVKLRVY-------------------GQNINN 112 Query: 101 DWAPRLVFIEEP-----PGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVA 155 + R+ F E PG G+ A P GPQRC ++ SD+ +L P Sbjct: 113 ETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRT---SDIIIL-PHIILNRR 168 Query: 156 GSALVQVRVRELRKGEAERG------------GAGG--------GGKLFSLCA------W 189 S ++++ ++ LRK E + GAGG GGK S A W Sbjct: 169 TSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPW 228 Query: 190 DGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSL 249 W +H ++ G L P WL+ + LLL LS +FSGL L L++L Sbjct: 229 AETTWIYHDGEDTKMI------VGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMAL 282 Query: 250 DPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYTSLPPGF 309 DP+ELR+++N G+ E+ A+R++ VR +G +LLC+LLLG N L T L Sbjct: 283 DPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTL-----TILLDDI 337 Query: 310 GGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAA 369 G+G + +V T + + EI P ++CSRHGLA+ ++++ LT+ M Sbjct: 338 AGSG-----------LVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMT 386 Query: 370 FPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVV 429 FP YP+ +LLD L QEI T Y REKLLE LR DPY+DLVKEELNIIQGALELRTK V Sbjct: 387 FPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTV 446 Query: 430 EEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDP 489 E+V+TPL DCFM+ +A+LDF T+SEI+ SGYTRIPV+EG+ R NIVD+LFVKDLAFVDP Sbjct: 447 EDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGE-RSNIVDLLFVKDLAFVDP 505 Query: 490 DDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMG 549 DDCTPL T+T+FYN PLH VFNDT+LD +LEEFKKGKSHLAIVQRVNNEGEGDPFYEV+G Sbjct: 506 DDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLG 565 Query: 550 IVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQL 609 IVTLED+IEEIIKSEILDETDLYTDNR K++V RERK+ DFS FK +D+EM+VKISPQL Sbjct: 566 IVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQ-DFSAFKQTDSEMKVKISPQL 624 Query: 610 LLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVD 669 LLA HRF+ATEVE F +SEKILLRLLKHPNVIQELK+DEKNKKAPE+YLYQRN+PVD Sbjct: 625 LLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVD 684 Query: 670 YFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLAGSSVFLNRS 729 YFVL+LQGKVEVE GKEG++FE AF+YYGV A+ +S N+S Sbjct: 685 YFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALT-----------------ASPGENKS 727 Query: 730 PSRCSGLNRSESPNR-ERSD-----FGGSNTQLYSSSNNLYMPDYSVHILSDVQFVKITR 783 P R GLN S+S +R +R D G SN QL SS +Y+PDYSV LSD+QFVKI+R Sbjct: 728 PPRPCGLNHSDSLSRSDRIDAVTPTLGSSNNQLNSSLLQVYIPDYSVRALSDLQFVKISR 787 Query: 784 QQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRNSLPCS 843 QQYQNAL A MD +PQS +D ++TK T D LLN +N + S Sbjct: 788 QQYQNALMASRMDKTPQS------SDSENTKIELTLTELHDGLPDETANLLNEQNCVTHS 841 Query: 844 RSD 846 +++ Sbjct: 842 KAN 844 >gi|94681046 cyclin M4 [Homo sapiens] Length = 775 Score = 640 bits (1652), Expect = 0.0 Identities = 341/627 (54%), Positives = 438/627 (69%), Gaps = 49/627 (7%) Query: 221 PAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRGT 280 P WL L +LL LS +FSGL L L++LDP+ELR+++N G+ E+ AR+++ +R +G Sbjct: 181 PLWLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGN 240 Query: 281 HLLCTLLLGQAGANAALAGWLYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAE 340 +LLC+LLLG N +L T L G+G + T + + E Sbjct: 241 YLLCSLLLGNVLVNTSL-----TILLDNLIGSG-----------LMAVASSTIGIVIFGE 284 Query: 341 ICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLET 400 I P ++CSRHGLA+ ++++ LT+ M FP+ +P+ +LLD+ L QEI T Y REKL+E Sbjct: 285 ILPQALCSRHGLAVGANTILLTKFFMLLTFPLSFPISKLLDFFLGQEIRTVYNREKLMEM 344 Query: 401 LRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSG 460 L+ +PY+DLVKEELN+IQGALELRTK VE+++T L DCFM+RSDA+LDF T+SEI+ SG Sbjct: 345 LKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLQDCFMIRSDAILDFNTMSEIMESG 404 Query: 461 YTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLE 520 YTRIPV+E D++ NIVDIL+VKDLAFVDPDDCTPL T+TRFYN P+H VF+DT+LD +LE Sbjct: 405 YTRIPVFE-DEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLE 463 Query: 521 EFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQR 580 EFKKGKSHLAIVQ+VNNEGEGDPFYEV+G+VTLED+IEEIIKSEILDE+D+YTDNR ++R Sbjct: 464 EFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRSRKR 523 Query: 581 VPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKH 640 V E+ + DFS FK +D E++VKISPQLLLA HRF+ATEV F +SEKILLRLLK+ Sbjct: 524 V--SEKNKRDFSAFKDADNELKVKISPQLLLAAHRFLATEVSQFSPSLISEKILLRLLKY 581 Query: 641 PNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGV 700 P+VIQELKFDE NK HYLY RN+P DYF+L+LQGKVEVE GKE ++FE GAF+YYG Sbjct: 582 PDVIQELKFDEHNKYYARHYLYTRNKPADYFILILQGKVEVEAGKENMKFETGAFSYYGT 641 Query: 701 PAIMTTACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSES---PNR----ERSDFGGSN 753 A+ +SV +RSP+ + L+RS S P+R + GS+ Sbjct: 642 MAL------------------TSVPSDRSPAHPTPLSRSASLSYPDRTDVSTAATLAGSS 683 Query: 754 TQLYSSSNNLYMPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDST 813 Q SS Y+ D+SV L D+Q++KITRQQYQN L A M++SPQ P DG +T Sbjct: 684 NQFGSSVLGQYISDFSVRALVDLQYIKITRQQYQNGLLASRMENSPQFP-----IDGCTT 738 Query: 814 KAPTTRGTPQTPKDDPAITLLNNRNSL 840 + P D TLLN RNSL Sbjct: 739 HMENLAEKSELPVVDETTTLLNERNSL 765 >gi|40068049 cyclin M3 isoform 1 [Homo sapiens] Length = 707 Score = 513 bits (1322), Expect = e-145 Identities = 307/605 (50%), Positives = 389/605 (64%), Gaps = 62/605 (10%) Query: 204 LLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSA 263 LL VR G + P W LGA LLAL+AL GL+LS L+L P E++VLR SGS Sbjct: 116 LLAVRVEPGGGAAEEAAPPWALGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSE 175 Query: 264 AEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYTSLPPGFGGTGEDYSEEGIHF 323 AE+ ARR++ R L LLL + A AALA LY + G+ Sbjct: 176 AERAAARRLEPARRWAGCALGALLLLASLAQAALAVLLYRA-------AGQRA------- 221 Query: 324 PWLPALV-CTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDW 382 +PA++ G VFL E+ P +V R LA+A ++ L+RL + PV P+G+LL+ Sbjct: 222 --VPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRLAVLLTLPVALPVGQLLEL 279 Query: 383 ALRQEISTFYTREKLLETLRAA-DPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFM 441 A R RE++LE R DPYSDL K G L RT VE+VLTPL DCFM Sbjct: 280 AARPG----RLRERVLELARGGGDPYSDLSK-------GVLRCRT--VEDVLTPLEDCFM 326 Query: 442 LRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRF 501 L + VLDF ++ I++SG+TRIPVYE ++R NIVD+L++KDLAFVDP+DCTPL T+TRF Sbjct: 327 LDASTVLDFGVLASIMQSGHTRIPVYE-EERSNIVDMLYLKDLAFVDPEDCTPLSTITRF 385 Query: 502 YNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEII 561 YN PLH VFNDT+LD VLEEFK+GKSHLAIVQ+VNNEGEGDPFYEV+G+VTLED+IEEII Sbjct: 386 YNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEII 445 Query: 562 KSEILDETDLYTD---NRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMA 618 +SEILDE++ Y D RK + +++ +FSLFK+SD E +V ISPQLLLAT RF++ Sbjct: 446 RSEILDESEDYRDTVVKRKPASLMAPLKRKEEFSLFKVSDDEYKVTISPQLLLATQRFLS 505 Query: 619 TEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGK 678 EV+ F L +SEK+LL LLKHP+V QE++FDE N+ A HYLYQR++PVDYF+L+LQG+ Sbjct: 506 REVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLATHHYLYQRSQPVDYFILILQGR 565 Query: 679 VEVEVGKEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNR 738 VEVE+GKEGL+FENGAFTYYGV A+ T S V SL L P Sbjct: 566 VEVEIGKEGLKFENGAFTYYGVSAL--TVPSSVHQSPVSSLQPIRHDLQPDP-------- 615 Query: 739 SESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVKITRQQYQNALTACHMDSS 798 G T ++ Y PDY+V LSD+Q +K+TR QY NAL A + Sbjct: 616 ------------GDGTH-----SSAYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQNL 658 Query: 799 PQSPD 803 PQSP+ Sbjct: 659 PQSPE 663 Score = 34.3 bits (77), Expect = 0.57 Identities = 84/329 (25%), Positives = 112/329 (34%), Gaps = 81/329 (24%) Query: 1 MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGG 60 MAAA AAA +G C A +P P L ED A G + GG Sbjct: 1 MAAAVAAAGRLGWLFAALCLGNAA----GEAAPGPRVLGFCL----EEDGAAGAGWVRGG 52 Query: 61 TLRAAEGTSFLLRVY---FQPGPPATAAPVPSPTLNSGENGTGDWA-------------- 103 R +FLLR++ F + AP + + G+W Sbjct: 53 AARDTPDATFLLRLFGPGFANSSWSWVAPEGAGCREEAASPAGEWRALLRLRLRAEAVRP 112 Query: 104 -PRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVA------G 156 L+ + PGGG +A P WA + G L +A Sbjct: 113 HSALLAVRVEPGGGAAEEAAPP--------------WALGLGAAGLLALAALARGLQLSA 158 Query: 157 SALVQVRVRELRK--GEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLL-------RV 207 AL V+ LR+ EAER A +L W G A G LL + Sbjct: 159 LALAPAEVQVLRESGSEAERAAA---RRLEPARRWAG------CALGALLLLASLAQAAL 209 Query: 208 RPRLYGPGGDLLPPAWLRALGALLL--------------LALSALFSGL-RLSLLSLDPV 252 LY G PA L + G + L LAL+ GL RL++L PV Sbjct: 210 AVLLYRAAGQRAVPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRLAVLLTLPV 269 Query: 253 ELRVLRNSGSAAEQEQARR--VQAVRGRG 279 L V + AA + R ++ RG G Sbjct: 270 ALPVGQLLELAARPGRLRERVLELARGGG 298 >gi|40068047 cyclin M3 isoform 2 [Homo sapiens] Length = 659 Score = 416 bits (1068), Expect = e-116 Identities = 268/602 (44%), Positives = 346/602 (57%), Gaps = 104/602 (17%) Query: 204 LLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSA 263 LL VR G + P W LGA LLAL+AL GL+LS L+L P E++VLR SGS Sbjct: 116 LLAVRVEPGGGAAEEAAPPWALGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSE 175 Query: 264 AEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYTSLPPGFGGTGEDYSEEGIHF 323 AE+ ARR++ R L LLL + A AALA LY + G+ Sbjct: 176 AERAAARRLEPARRWAGCALGALLLLASLAQAALAVLLYRA-------AGQRA------- 221 Query: 324 PWLPALV-CTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDW 382 +PA++ G VFL E+ P +V R LA+A ++ L+RL + PV P+G+LL+ Sbjct: 222 --VPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRLAVLLTLPVALPVGQLLEL 279 Query: 383 ALRQEISTFYTREKLLETLRAA-DPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFM 441 A R RE++LE R DPYSDL K G L RT VE+VLTPL DCFM Sbjct: 280 AARPG----RLRERVLELARGGGDPYSDLSK-------GVLRCRT--VEDVLTPLEDCFM 326 Query: 442 LRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRF 501 L + VLDF ++ I++SG+TRIPVYE ++R NIVD+L++KDLAFVDP+DCTPL T+TRF Sbjct: 327 LDASTVLDFGVLASIMQSGHTRIPVYE-EERSNIVDMLYLKDLAFVDPEDCTPLSTITRF 385 Query: 502 YNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEII 561 YN PLH VFNDT+LD VLEEFK+G + ++ Sbjct: 386 YNHPLHFVFNDTKLDAVLEEFKRG--------------------------------DTVV 413 Query: 562 KSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMATEV 621 K RK + +++ +FSLFK+SD E +V ISPQLLLAT RF++ EV Sbjct: 414 K-------------RKPASLMAPLKRKEEFSLFKVSDDEYKVTISPQLLLATQRFLSREV 460 Query: 622 EPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGKVEV 681 + F L +SEK+LL LLKHP+V QE++FDE N+ A HYLYQR++PVDYF+L+LQG+VEV Sbjct: 461 DVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLATHHYLYQRSQPVDYFILILQGRVEV 520 Query: 682 EVGKEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSES 741 E+GKEGL+FENGAFTYYGV A+ T S V SL L P Sbjct: 521 EIGKEGLKFENGAFTYYGVSAL--TVPSSVHQSPVSSLQPIRHDLQPDP----------- 567 Query: 742 PNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQS 801 G T ++ Y PDY+V LSD+Q +K+TR QY NAL A + PQS Sbjct: 568 ---------GDGTH-----SSAYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQNLPQS 613 Query: 802 PD 803 P+ Sbjct: 614 PE 615 Score = 34.3 bits (77), Expect = 0.57 Identities = 84/329 (25%), Positives = 112/329 (34%), Gaps = 81/329 (24%) Query: 1 MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGG 60 MAAA AAA +G C A +P P L ED A G + GG Sbjct: 1 MAAAVAAAGRLGWLFAALCLGNAA----GEAAPGPRVLGFCL----EEDGAAGAGWVRGG 52 Query: 61 TLRAAEGTSFLLRVY---FQPGPPATAAPVPSPTLNSGENGTGDWA-------------- 103 R +FLLR++ F + AP + + G+W Sbjct: 53 AARDTPDATFLLRLFGPGFANSSWSWVAPEGAGCREEAASPAGEWRALLRLRLRAEAVRP 112 Query: 104 -PRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVA------G 156 L+ + PGGG +A P WA + G L +A Sbjct: 113 HSALLAVRVEPGGGAAEEAAPP--------------WALGLGAAGLLALAALARGLQLSA 158 Query: 157 SALVQVRVRELRK--GEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLL-------RV 207 AL V+ LR+ EAER A +L W G A G LL + Sbjct: 159 LALAPAEVQVLRESGSEAERAAA---RRLEPARRWAG------CALGALLLLASLAQAAL 209 Query: 208 RPRLYGPGGDLLPPAWLRALGALLL--------------LALSALFSGL-RLSLLSLDPV 252 LY G PA L + G + L LAL+ GL RL++L PV Sbjct: 210 AVLLYRAAGQRAVPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRLAVLLTLPV 269 Query: 253 ELRVLRNSGSAAEQEQARR--VQAVRGRG 279 L V + AA + R ++ RG G Sbjct: 270 ALPVGQLLELAARPGRLRERVLELARGGG 298 >gi|40068051 cyclin M2 isoform 3 [Homo sapiens] Length = 552 Score = 365 bits (937), Expect = e-100 Identities = 227/515 (44%), Positives = 296/515 (57%), Gaps = 80/515 (15%) Query: 42 LLGLRPEDTAGGRVS-LEGGTLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTG 100 ++GLR EDT VS +EGG LR +E T LRVY G+N Sbjct: 74 IIGLRLEDT--NDVSFMEGGALRVSERTRVKLRVY-------------------GQNINN 112 Query: 101 DWAPRLVFIEEP-----PGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVA 155 + R+ F E PG G+ A P GPQRC ++ SD+ +L P Sbjct: 113 ETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRT---SDIIIL-PHIILNRR 168 Query: 156 GSALVQVRVRELRKGEAERG------------GAGG--------GGKLFSLCA------W 189 S ++++ ++ LRK E + GAGG GGK S A W Sbjct: 169 TSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPW 228 Query: 190 DGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSL 249 W +H ++ G L P WL+ + LLL LS +FSGL L L++L Sbjct: 229 AETTWIYHDGEDTKMI------VGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMAL 282 Query: 250 DPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYTSLPPGF 309 DP+ELR+++N G+ E+ A+R++ VR +G +LLC+LLLG N L T L Sbjct: 283 DPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTL-----TILLDDI 337 Query: 310 GGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAA 369 G+G + +V T + + EI P ++CSRHGLA+ ++++ LT+ M Sbjct: 338 AGSG-----------LVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMT 386 Query: 370 FPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVV 429 FP YP+ +LLD L QEI T Y REKLLE LR DPY+DLVKEELNIIQGALELRTK V Sbjct: 387 FPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTV 446 Query: 430 EEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDP 489 E+V+TPL DCFM+ +A+LDF T+SEI+ SGYTRIPV+EG +R NIVD+LFVKDLAFVDP Sbjct: 447 EDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEG-ERSNIVDLLFVKDLAFVDP 505 Query: 490 DDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKK 524 DDCTPL T+T+FYN PLH VFNDT+LD +LEEFKK Sbjct: 506 DDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK 540 >gi|92859678 small nuclear RNA activating complex, polypeptide 4, 190kDa [Homo sapiens] Length = 1469 Score = 37.0 bits (84), Expect = 0.088 Identities = 49/164 (29%), Positives = 61/164 (37%), Gaps = 20/164 (12%) Query: 74 VYFQPGPPATAAPVPSPTLNSGEN---GTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGP 130 V F PG A +P P +S + W+ RL P GGV P+ P PG Sbjct: 1171 VAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRL------PAFGGVIPATEPRGTPGS 1224 Query: 131 QRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWD 190 ++ +E L PLR G AL +L K + G G L + + Sbjct: 1225 PSGTQEPRGPLGLEKL-PLRQPGPEKGAL------DLEKPPLPQPGPEKGALDLGLLSQE 1277 Query: 191 GRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAW--LRALGALLL 232 G A G VR L G PPA LRAL LLL Sbjct: 1278 GEAATQQWLGG--QRGVRVPLLGSRLPYQPPALCSLRALSGLLL 1319 >gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] Length = 2778 Score = 36.6 bits (83), Expect = 0.11 Identities = 39/115 (33%), Positives = 46/115 (40%), Gaps = 25/115 (21%) Query: 80 PPA--TAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRP----PGPQRC 133 PPA + P +P L +G G W P GGG P A+P GP Sbjct: 2655 PPAFRRSEPFLAPLLLTGAGGP--WGPM---------GGGCCPPAIPATTAGLRAGPITL 2703 Query: 134 REQSDWASDVEVL------GPLRPGGVA-GSALVQVRVRELRKGEAERGGAGGGG 181 D + V L GP P G GSALV +R R L + GGAGG G Sbjct: 2704 EPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHR-LHEYCGGGGGAGGSG 2757 >gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens] Length = 2161 Score = 36.6 bits (83), Expect = 0.11 Identities = 34/104 (32%), Positives = 44/104 (42%), Gaps = 6/104 (5%) Query: 30 SLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSF--LLRVYFQPGPPATAAPV 87 +L P+P + W G P T G G+ G+S LR YFQ P A +A + Sbjct: 1040 ALGPQP-SLRGWRGG-GPSPTPGAPSPSHHGSAGGGGGSSQGPALR-YFQLPPRAASAAM 1096 Query: 88 PSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQ 131 P SG G + EP GGG+ P+ PT P PQ Sbjct: 1097 YVPA-RSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQ 1139 Score = 31.6 bits (70), Expect = 3.7 Identities = 52/180 (28%), Positives = 62/180 (34%), Gaps = 57/180 (31%) Query: 26 LLFFSLSPRPPAAAAWLLGLRPEDTAG---------GRVSLEGGTLRAAEGTSFLLRVYF 76 L +F L PR +AA ++ G G GG A TS Sbjct: 1082 LRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTS---PASP 1138 Query: 77 QPGPPATAAP-----VPSPTL--------NSGENGTGDWAPRLVFIEEPP---------G 114 QP PPA AAP +P PT+ +SG + G EPP G Sbjct: 1139 QP-PPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEA-----EPPTQPEPTGGGG 1192 Query: 115 GGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVA--------GSALVQVRVRE 166 GGG +PS P P P S V P P G A G+ALV RE Sbjct: 1193 GGGSSPSPAPAMSPVP---------PSPSPVPTPASPSGPATLDFTSQFGAALVGAARRE 1243 >gi|39812378 RAN binding protein 9 [Homo sapiens] Length = 729 Score = 36.2 bits (82), Expect = 0.15 Identities = 33/96 (34%), Positives = 40/96 (41%), Gaps = 12/96 (12%) Query: 33 PRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAAPVPSPT- 91 P PPA +A G P + GG EG AA LL P PPATAAP P P Sbjct: 36 PAPPAVSA---GSSPAGSPGGGAGGEGLGAAAAA----LLLHPPPPPPPATAAPPPPPPP 88 Query: 92 ----LNSGENGTGDWAPRLVFIEEPPGGGGVAPSAV 123 ++ +G AP + P GG P+ V Sbjct: 89 PPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALV 124 Score = 32.0 bits (71), Expect = 2.8 Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 10/81 (12%) Query: 78 PGPPATAA---PVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCR 134 P PPA +A P SP +G G G A L+ PP A P PP P Sbjct: 36 PAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPA-- 93 Query: 135 EQSDWASDVEVLGPLRPGGVA 155 ++ GP P G+A Sbjct: 94 -----SAAAPASGPPAPPGLA 109 >gi|239746493 PREDICTED: hypothetical protein XP_002343745 [Homo sapiens] Length = 529 Score = 35.4 bits (80), Expect = 0.25 Identities = 44/149 (29%), Positives = 53/149 (35%), Gaps = 28/149 (18%) Query: 1 MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLR------------PE 48 + A+A AA R R+ A L F PPA+ W R PE Sbjct: 29 LGASAPPLAAAASRTRE--GTEAALSAGFQDRDPPPASRDWYRQRRAGRSLIRQFRRTPE 86 Query: 49 DTAGGRVSLEGGTLRAA---EGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPR 105 T GR+ LE T A F R P PP AP + G D +PR Sbjct: 87 ATPQGRLGLESRTRLAPCALRPDRFPRRF---PEPPPQPAPPAGGARKERDAGAADLSPR 143 Query: 106 LVFIEEPPGGGGVA--PSAVPTRPPGPQR 132 PG GVA P T+ GP+R Sbjct: 144 ------RPGRSGVARRPGDARTQSAGPER 166 >gi|222352127 sidekick 2 [Homo sapiens] Length = 2172 Score = 35.0 bits (79), Expect = 0.33 Identities = 43/154 (27%), Positives = 60/154 (38%), Gaps = 26/154 (16%) Query: 709 SDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDY 768 SD DV K L P+ S L S E SD GS+++ SN+ + Sbjct: 2026 SDEDVTKYNDLI---------PAESSSLTEKPS---EISDSQGSDSEYEVDSNHQKAHSF 2073 Query: 769 SVHILSDVQFVKITRQQYQ---NALTACHMDSSPQSPDMEAFTDGDST--------KAPT 817 H +SD + R+Q + A + +S PD T+ ST KA Sbjct: 2074 VNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTTVTNSTSTQQGSLFRPKASR 2133 Query: 818 TRGTPQTPKDDPAITLLNNRNSLPCSRSDGLRSP 851 T TPQ P + P+ R P S + G R+P Sbjct: 2134 T-PTPQNPPNPPSQQSTLYRP--PSSLAPGSRAP 2164 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 35.0 bits (79), Expect = 0.33 Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 13/90 (14%) Query: 78 PGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQS 137 P PP P P P +G +G + PP G G P P PP P Sbjct: 359 PPPPGRGGPPPPPPPATGRSGP---------LPPPPPGAGGPPMPPPPPPPPPPPSSGNG 409 Query: 138 DWASDVE----VLGPLRPGGVAGSALVQVR 163 + G L PGG G+ L Q+R Sbjct: 410 PAPPPLPPALVPAGGLAPGGGRGALLDQIR 439 >gi|133922582 zinc finger protein 358 [Homo sapiens] Length = 568 Score = 35.0 bits (79), Expect = 0.33 Identities = 39/137 (28%), Positives = 52/137 (37%), Gaps = 15/137 (10%) Query: 2 AAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGT 61 AAAAAAAAA G+ L S +++ RP + LLG G + L GT Sbjct: 407 AAAAAAAAAAGLGLGPGLSPASMM--------RPGQVS--LLGPDAVSVLGSGLGLSPGT 456 Query: 62 LRA-----AEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGG 116 G L +P P + + P P+P +S D P LV + Sbjct: 457 SSGRNPDPGSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDAGPDLVPSPDLDPVP 516 Query: 117 GVAPSAVPTRPPGPQRC 133 P VP+ P P C Sbjct: 517 SPDPDPVPSPDPNPVSC 533 >gi|62241036 hypothetical protein LOC541565 [Homo sapiens] Length = 365 Score = 34.7 bits (78), Expect = 0.43 Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 6/68 (8%) Query: 72 LRVYFQPGPP----ATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRP 127 LR+ PG P +T AP+PSP G G G W L+ E G +P V Sbjct: 212 LRIQRPPGDPGEEESTRAPLPSPLHTPGNRGQGPW--ELLSQTEHTGAKAASPPKVEVPS 269 Query: 128 PGPQRCRE 135 P R E Sbjct: 270 ANPPRLPE 277 >gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo sapiens] Length = 3969 Score = 34.3 bits (77), Expect = 0.57 Identities = 37/149 (24%), Positives = 50/149 (33%), Gaps = 18/149 (12%) Query: 41 WLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRV---YFQPGPPA----TAAPVPSPTLN 93 W RP T GG GG R G + RV PGPP AP P + Sbjct: 7 WRFPARPGTTGGG-----GGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVA 61 Query: 94 SGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGG 153 + G + PGG A +A + + + +GP Sbjct: 62 AAAAAAGSSGAGV------PGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAA 115 Query: 154 VAGSALVQVRVRELRKGEAERGGAGGGGK 182 + SA + +R R E GG GG G+ Sbjct: 116 LQVSAAIGTNLRRFRAVFGESGGGGGSGE 144 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 34.3 bits (77), Expect = 0.57 Identities = 44/151 (29%), Positives = 55/151 (36%), Gaps = 22/151 (14%) Query: 78 PGPPATAAP--VPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCRE 135 PGPP A P P NSGE G + + F PPG G PPGPQ + Sbjct: 1128 PGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGF-PGPPGPPGFPGKVGSPGPPGPQ-AEK 1185 Query: 136 QSDWASDVEVL----GPLRPGGVAGSA-LVQVRVRELRKGEAERGGAGGGGKLFSLCAWD 190 S+ L GP P G+ G A L + ++ + G G G L + Sbjct: 1186 GSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFK 1245 Query: 191 GRAWHHHGAAGGFLLRVRPRLYGPGGDLLPP 221 G+ H P L GP GD P Sbjct: 1246 GKTGH-------------PGLPGPKGDCGKP 1263 >gi|115511036 alpha-kinase 3 [Homo sapiens] Length = 1907 Score = 34.3 bits (77), Expect = 0.57 Identities = 37/130 (28%), Positives = 44/130 (33%), Gaps = 24/130 (18%) Query: 98 GTGDWAPRLVFIEEPPGGGGVAPS-----AVPTRPPGPQRCREQSDWASDVEVLGP---- 148 G G WAP + +P G P RPP R Q + GP Sbjct: 124 GAGTWAPAPPGVSKPRCPGRARPGEGQQQVTTARPPAINRGARQPRAGAAAAGRGPGAGA 183 Query: 149 LRPGGVA---------GSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGA 199 R G A G A+ R G R GAGG G+ DG W A Sbjct: 184 WRTGEAAASAGPAVGEGGAMGSRRAPSRGWGAGGRSGAGGDGED------DGPVWIPSPA 237 Query: 200 AGGFLLRVRP 209 + +LL VRP Sbjct: 238 SRSYLLSVRP 247 >gi|118200352 hypothetical protein LOC642273 [Homo sapiens] Length = 321 Score = 33.9 bits (76), Expect = 0.74 Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 46/179 (25%) Query: 33 PRPPAAAAWLLG--------LRPEDTAGGRVSLEGGTLRAAEGT-SFLLRVYFQPGPPAT 83 P PPA A + LRP+ R E A+G + L++ FQ GP Sbjct: 75 PGPPARAPAPVARRAIARKPLRPDSLIIYRQKCEFVRGSGADGPRASLVKKLFQ-GPGKD 133 Query: 84 AAPVPSPTLNSGENGTGDWAPRL-------VFIEEP-PGGGGVAPSAVPTRPPGPQ---- 131 APVP T + G+ G + P E P P APS+VP PPGP+ Sbjct: 134 KAPVPR-TGDEGKAGNPETVPTTPGPAADPATPETPAPAARSAAPSSVPAAPPGPEPRVV 192 Query: 132 ----RCREQSDWAS------------------DVEVLGPL-RPGGVAGSALVQVRVREL 167 R QSD +S D EV+ L R AGS V ++VR + Sbjct: 193 RRRGLQRSQSDLSSRYSAALAESDTFFQYCGLDPEVVEALGRENFTAGSDCVTLKVRSV 251 >gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo sapiens] Length = 425 Score = 33.9 bits (76), Expect = 0.74 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 12/100 (12%) Query: 114 GGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLR---PGGVAGSALVQVRV------ 164 G GG PSA+ P R R +S +S P R PGG G + Sbjct: 251 GSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLS 310 Query: 165 RELRKGEAERG--GAGGGGKLFSLCAWDGRAWHHHGAAGG 202 R+ KG G GAGGGG ++ A+ G A G GG Sbjct: 311 RDPSKGSVAAGLAGAGGGGG-GAVGAFGGAAGGAGGGGGG 349 >gi|27734911 DAZ interacting protein 1-like [Homo sapiens] Length = 767 Score = 33.9 bits (76), Expect = 0.74 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 13/106 (12%) Query: 80 PPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDW 139 PP++ + +P +S E+ GD R+ +PP PS + RP ++ DW Sbjct: 603 PPSSGPGMSTPPFSSEEDSEGDRVQRVSL--QPP----KVPSRMVPRP------KDDWDW 650 Query: 140 ASDVEVLGPLRPGGVAGSALVQVRVRELRKG-EAERGGAGGGGKLF 184 + +P G LVQ V+ L K EA GG LF Sbjct: 651 SDTETSEENAQPPGQGSGTLVQSMVKNLEKQLEAPAKKPAGGVSLF 696 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 33.5 bits (75), Expect = 0.97 Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 16/113 (14%) Query: 77 QPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQ 136 QP PP P P P L S G P + PP G P P PP P Sbjct: 603 QPPPPPPPPPPPPPYLASLPLGYPPHQPAYLL---PPRPDGPPPPEYPPPPPPPPHI--- 656 Query: 137 SDWASDVEVLGPL--RPGGVAGSALVQ----VRVRELRKGE----AERGGAGG 179 D+ + +E++ L + GG+ S +Q R+ +LR+G+ A G GG Sbjct: 657 YDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLIAASAGPPGG 709 >gi|50511941 EMI domain containing 1 [Homo sapiens] Length = 443 Score = 33.5 bits (75), Expect = 0.97 Identities = 36/133 (27%), Positives = 49/133 (36%), Gaps = 17/133 (12%) Query: 30 SLSPRPPAAAAWLLGLRPEDTAG----GRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAA 85 SL P + + LRP +G +VS L+ E +L V QP PP A Sbjct: 113 SLEPMWSGSTMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPAT 172 Query: 86 PV-PSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVE 144 P P+P W P + PG GG+ PGP + + + Sbjct: 173 PEDPAPL----------WGPPPA--QGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMG 220 Query: 145 VLGPLRPGGVAGS 157 + GP P G GS Sbjct: 221 MRGPPGPQGPPGS 233 Score = 32.3 bits (72), Expect = 2.2 Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 7/109 (6%) Query: 78 PGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEE----PPGGGGVAPSAVPTRPPGPQRC 133 PGPP APV P ++ GD F E P G G P PPGP Sbjct: 255 PGPPGPPAPVGPPHARISQH--GDPLLSNTFTETNNHWPQGPTGPPGPPGPMGPPGPPGP 312 Query: 134 REQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGK 182 + GP P G++G + R LR +G AG G+ Sbjct: 313 TGVPGSPGHIGPPGPTGPKGISGHP-GEKGERGLRGEPGPQGSAGQRGE 360 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 33.5 bits (75), Expect = 0.97 Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 11/127 (8%) Query: 32 SPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEG-TSFLLRVYFQPGPPATAAPVPSP 90 SP PP+ P +A +S +G TL E T ++ + F PAT AP +P Sbjct: 855 SPTPPSPKG-----APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909 Query: 91 TLN----SGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVL 146 L+ S + AP+ + P G P+A P P G WA Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP-ATPSPKWAPTPPAA 968 Query: 147 GPLRPGG 153 P P G Sbjct: 969 TPPSPKG 975 Score = 30.4 bits (67), Expect = 8.2 Identities = 15/48 (31%), Positives = 23/48 (47%) Query: 81 PATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPP 128 P ++P PT +SG + T L ++ + P GV+ S RPP Sbjct: 762 PVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809 >gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] Length = 993 Score = 33.5 bits (75), Expect = 0.97 Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 12/77 (15%) Query: 76 FQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCRE 135 FQP PPA P P P L + ++ R VF P A +AVPT+P + Sbjct: 94 FQPDPPAPFTPSPLPRLANQDS-------RPVFTSPTP-----AMAAVPTQPQSKEGPWS 141 Query: 136 QSDWASDVEVLGPLRPG 152 + + + PL PG Sbjct: 142 PESESPMLRITAPLPPG 158 >gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] Length = 994 Score = 33.5 bits (75), Expect = 0.97 Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 12/77 (15%) Query: 76 FQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCRE 135 FQP PPA P P P L + ++ R VF P A +AVPT+P + Sbjct: 94 FQPDPPAPFTPSPLPRLANQDS-------RPVFTSPTP-----AMAAVPTQPQSKEGPWS 141 Query: 136 QSDWASDVEVLGPLRPG 152 + + + PL PG Sbjct: 142 PESESPMLRITAPLPPG 158 >gi|239757128 PREDICTED: similar to mCG141871 [Homo sapiens] Length = 306 Score = 33.1 bits (74), Expect = 1.3 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 3/94 (3%) Query: 37 AAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAAPVP---SPTLN 93 AAA L R GGRV+ GG +A SF P PP AAP P P + Sbjct: 5 AAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFS 64 Query: 94 SGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRP 127 + T D PR E P V A RP Sbjct: 65 LKLSDTEDVFPRRAGPLEVPADSRVFVQAALARP 98 >gi|113428456 PREDICTED: similar to mCG141871 [Homo sapiens] Length = 358 Score = 33.1 bits (74), Expect = 1.3 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 3/94 (3%) Query: 37 AAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAAPVP---SPTLN 93 AAA L R GGRV+ GG +A SF P PP AAP P P + Sbjct: 57 AAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFS 116 Query: 94 SGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRP 127 + T D PR E P V A RP Sbjct: 117 LKLSDTEDVFPRRAGPLEVPADSRVFVQAALARP 150 >gi|113428072 PREDICTED: similar to mCG141871 [Homo sapiens] Length = 358 Score = 33.1 bits (74), Expect = 1.3 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 3/94 (3%) Query: 37 AAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAAPVP---SPTLN 93 AAA L R GGRV+ GG +A SF P PP AAP P P + Sbjct: 57 AAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFS 116 Query: 94 SGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRP 127 + T D PR E P V A RP Sbjct: 117 LKLSDTEDVFPRRAGPLEVPADSRVFVQAALARP 150 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.136 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 40,445,947 Number of Sequences: 37866 Number of extensions: 2192143 Number of successful extensions: 8442 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 103 Number of HSP's that attempted gapping in prelim test: 8204 Number of HSP's gapped (non-prelim): 299 length of query: 951 length of database: 18,247,518 effective HSP length: 112 effective length of query: 839 effective length of database: 14,006,526 effective search space: 11751475314 effective search space used: 11751475314 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.