Guide to the Human Genome
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Name: PLEK Sequence: fasta or formatted (350aa) NCBI GI: 156616273
Description:

pleckstrin

Referenced in:

Inositol Pathways
Additional Interaction Domain Families

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.7         20           2
 C cysteine            2.0          7           1
 D aspartate           6.3         22           3
 E glutamate           8.0         28           3
 F phenylalanine       5.7         20           2
 G glycine             6.9         24           2
 H histidine           1.7          6           1
 I isoleucine          6.3         22           2
 K lysine              9.4         33           3
 L leucine             7.7         27           2
 M methionine          2.3          8           1
 N asparagine          4.3         15           1
 P proline             4.0         14           1
 Q glutamine           3.4         12           2
 R arginine            6.0         21           2
 S serine              6.3         22           2
 T threonine           4.6         16           3
 V valine              4.9         17           2
 W tryptophan          1.7          6           1
 Y tyrosine            2.9         10           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pleckstrin 
PLEK2                 0.326   pleckstrin 2 
SWAP70                0.043   SWAP-70 protein 
ARHGAP24              0.043   Rho GTPase activating protein 24 isoform 1 
PLEKHA2               0.042   pleckstrin homology domain containing, family A (ph...
PLEKHA1               0.042   pleckstrin homology domain containing, family A (pho...
PLEKHA1               0.042   pleckstrin homology domain containing, family A (pho...
DEF6                  0.040   differentially expressed in FDCP 6 homolog 
CYTH4                 0.039   cytohesin 4 
ARHGAP25              0.039   Rho GTPase activating protein 25 isoform a 
ARHGAP25              0.039   Rho GTPase activating protein 25 isoform b 
CYTH2                 0.038   cytohesin 2 isoform 2 
RASA1                 0.038   RAS p21 protein activator 1 isoform 1 
RASA1                 0.038   RAS p21 protein activator 1 isoform 2 
CYTH1                 0.036   cytohesin 1 isoform 2 
ARHGAP22              0.036   Rho GTPase activating protein 2 
GAB4                  0.035   GRB2-associated binding protein family, member 4 [Ho...
FARP1                 0.035   FERM, RhoGEF, and pleckstrin domain protein 1 isoform...
GAB1                  0.033   GRB2-associated binding protein 1 isoform b 
GAB1                  0.033   GRB2-associated binding protein 1 isoform a 
GAB2                  0.032   GRB2-associated binding protein 2 isoform a 
CYTH2                 0.032   cytohesin 2 isoform 1 
PLEKHA6               0.032   phosphoinositol 3-phosphate-binding protein-3 
AKT2                  0.030   AKT2 kinase 
CYTH3                 0.030   cytohesin 3 
CYTH1                 0.029   cytohesin 1 isoform 1 
FARP2                 0.029   FERM, RhoGEF and pleckstrin domain protein 2 
PLEKHH1               0.029   pleckstrin homology domain containing, family H (wit...
OSBPL11               0.027   oxysterol binding protein-like 11 
OSBPL9                0.026   oxysterol binding protein-like 9 isoform e 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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